LOCUS       c00060_3300014..        6441 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300014869.a:Ga0180298_1001178.
ACCESSION   c00060_3300014..
VERSION     c00060_3300014..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 06:54:14
            Original ID  :: 3300014869.a:Ga0180298_1001178
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6441
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6441
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1364:5366](+)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1365..5366
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..6441
                     /SMILES="NC(C(O)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6441
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             347..490
                     /locus_tag="ctg60_1"
                     /transl_table=11
                     /translation="MSNDYEIEPTRSVLFKSAACLALDFENYREAERMIALELLGNPPQ
                     KI"
     CDS             1365..5366
                     /NRPS_PKS="Domain: AMP-binding (609-1015). E-value:
                     1.3e-117. Score: 384.6. Matches aSDomain:
                     nrpspksdomains_ctg60_2_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1233-1302). E-value: 6.4e-22.
                     Score: 69.3. Matches aSDomain:
                     nrpspksdomains_ctg60_2_PCP.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1228:methionyl-tRNA formyltransferase (Score: 125.1;
                     E-value: 4.5e-38)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg60_2"
                     /sec_met_domain="AMP-binding (E-value: 3.1e-126, bitscore:
                     408.9, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6.8e-16, bitscore:
                     46.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCTKCIYQLFEAQVELDACEANKMMPQKKQFTCFMIGEGTLVIQC
                     AKHILEQAHQILGMISHDEAVTHWANRKGIPCIQATDKLIDFLSQQPFDYLFSIINFSV
                     LPKDILLLPRQYAINYHDAPLPKYAGINATSWGIINQEKTWGVTWHIMSERIDGGDILK
                     QTPIEIAQNETAFTLNLKCYEAAIHSFKQLSDELSCDQVVARPQKVEERSYFSRFNKSS
                     KGCLLSWNRKAHEIDAWVRALDFGSSPNPLGLAKFWLGSDFVIMNKIDVLDALSTSPPG
                     TITAIDDNGIKVATASDDVTLRQVKTIEGQTLSIPDFVTKFGLHEGYQFKEINPNLAKR
                     IEHFDALLAKHEAFWVERLATLQPITIPYITQSASPLKRQRTFKTIEIPMPTEVTNFLN
                     ECHTTWHKSDFMLVAFVAYLSRIGDKPSFDIGFKDVELQTELAGIEGLLASYKPCRITV
                     EPENRFDKIFDAVQEQIALVKRHKTYIRDIVIRYPVLASKAELRNEPLYPVIIERVEKR
                     ENHKIGLGYDLSLIIQENDQKCYWFYDTAVLDDDSITRMLGQLTAFMQGIVTHSAKRIS
                     EFPLLSEQERHQILVEWNNTQVDYPKDVCLHQLFEAQVERTPDAVALVFENKQLSYREL
                     NQRANQLAHHLINLGVKPETLVGICIERSLEMVVGLLGILKAGGAYLPLEPTYPNVRLA
                     FMLEDAQVSVLLTQEKLIKKLPDHIEHIICLDTDWKIISLLSWENPISGVSPKNLVYVI
                     YTSGSTGKPKGVLLNHYNVVRLFKATNSWFHFSEQDVWTLFHSLAFDFSVWELWGAFFY
                     GGCLVIVPYWVSRSPQQFYELLYTEQVTILNQTPAAFQQLIRIKDSSKIFQALNLRFII
                     FGGESLDFNTLKHWFEQHGDEYPQLINMYGITETTVHVTYHPIKMAEIGKGSIIGCPIH
                     DLQVYILENNLQPVPIGIVGEMYIGGAGLARGYLNRPELTAEKFIPNPFNNDPKARLYK
                     TGDLARYLPDGNIEYLGRIDNQVKMRGFRIELGEIETLLNQDSTVLEAVVIARDDESGH
                     QRLIAYIVSKLILERLPLKTSCLVELDHQSPITLTTEDISCEGVCLVGVPQTLETGQHV
                     RIRRLQLPDISDDQLGLEGHIAWCQGQRAGIQFAFTNLSTRVHFCQIIDNLFETQGIIK
                     VMQRTSSAHLRDVLRQKLPDYMIPSSFIFLKAIPLTPNGKVDRKALPQLDGQRADLETA
                     YLAPETEIEQKIARILQTVLQVNQVGIHDNFFDLGGNSLLLVQVQEKLVEVLNREVPVL
                     TLFQYPTINALLHYLEEDSPSEQMALKKSYDRAHKAKSAVHQFRKHHKA"
     aSDomain        3192..4409
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg60_2_AMP-binding.1"
                     /evalue="1.30E-117"
                     /label="ctg60_2_AMP-binding.1"
                     /locus_tag="ctg60_2"
                     /protein_end="1015"
                     /protein_start="609"
                     /score="384.6"
                     /specificity="consensus: thr"
                     /tool="antismash"
                     /translation="FEAQVERTPDAVALVFENKQLSYRELNQRANQLAHHLINLGVKPE
                     TLVGICIERSLEMVVGLLGILKAGGAYLPLEPTYPNVRLAFMLEDAQVSVLLTQEKLIK
                     KLPDHIEHIICLDTDWKIISLLSWENPISGVSPKNLVYVIYTSGSTGKPKGVLLNHYNV
                     VRLFKATNSWFHFSEQDVWTLFHSLAFDFSVWELWGAFFYGGCLVIVPYWVSRSPQQFY
                     ELLYTEQVTILNQTPAAFQQLIRIKDSSKIFQALNLRFIIFGGESLDFNTLKHWFEQHG
                     DEYPQLINMYGITETTVHVTYHPIKMAEIGKGSIIGCPIHDLQVYILENNLQPVPIGIV
                     GEMYIGGAGLARGYLNRPELTAEKFIPNPFNNDPKARLYKTGDLARYLPDGNIEYLGRI
                     DNQVKMRG"
     aSModule        3192..5270
                     /complete
                     /domains="nrpspksdomains_ctg60_2_AMP-binding.1"
                     /domains="nrpspksdomains_ctg60_2_PCP.1"
                     /locus_tags="ctg60_2"
                     /monomer_pairings="thr -> thr"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       3378..3416
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg60_2_0001"
                     /evalue="8.30E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg60_2"
                     /protein_end="684"
                     /protein_start="671"
                     /score="15.9"
                     /tool="antismash"
                     /translation="LGILKAGGAYLPLE"
     CDS_motif       3615..3671
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg60_2_0002"
                     /evalue="1.30E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg60_2"
                     /protein_end="769"
                     /protein_start="750"
                     /score="30.0"
                     /tool="antismash"
                     /translation="YVIYTSGSTGKPKGVLLNHY"
     CDS_motif       4197..4286
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg60_2_0003"
                     /evalue="2.10E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg60_2"
                     /protein_end="974"
                     /protein_start="944"
                     /score="58.4"
                     /tool="antismash"
                     /translation="PIGIVGEMYIGGAGLARGYLNRPELTAEKFI"
     CDS_motif       4374..4439
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg60_2_0004"
                     /evalue="4.40E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg60_2"
                     /protein_end="1025"
                     /protein_start="1003"
                     /score="37.9"
                     /tool="antismash"
                     /translation="YLGRIDNQVKMRGFRIELGEIET"
     aSDomain        5064..5270
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg60_2_PCP.1"
                     /evalue="6.40E-22"
                     /label="ctg60_2_PCP.1"
                     /locus_tag="ctg60_2"
                     /protein_end="1302"
                     /protein_start="1233"
                     /score="69.3"
                     /tool="antismash"
                     /translation="EQKIARILQTVLQVNQVGIHDNFFDLGGNSLLLVQVQEKLVEVLN
                     REVPVLTLFQYPTINALLHYLEEDS"
     CDS             5665..6300
                     /locus_tag="ctg60_3"
                     /transl_table=11
                     /translation="MKTATFKEWTLTTLDKAFGLCQIWECALMDNWENQEIEIDDFEKK
                     TLLNLQKHQIRGGRAWNEVELENKFISPVIMTANIDDEQIGYFLERRLSGIVGDYELSG
                     IVDGMIATGFRDPDIPLFCLHEYKHRCDNQGSPDAQALAAMLVAREQNDNQKAIYDVFV
                     VGLVWNFMILNGNEYFISKTYHADEEEIFAIFKMLKVLKKIIKDNLIN"
ORIGIN
        1 atattttaaa attgaacaat tgaacactca ttggcctctc gttgatattt taaaatggaa
       61 caattgaaca ctcatttcac ccatattgac ctctaaaact gaacaacggg acattcaaaa
      121 atagttaaca aaatcaacta cttattttta ttcttttttc tgacataaca gacattatac
      181 cgattaaatt taagtttcgc gccaaaagtt gaggcaaaca aaactttttt tgctctttga
      241 tttcattact tttcccaaaa tgggaatatt aataaaatca atttttcacg caaaagtttt
      301 tgtttgcctc aacttattaa gtgaaaagtt gtgttaaatc ggtataatgt ctaatgacta
      361 cgagattgaa ccaacccgtt ccgttttatt caaaagtgcg gcctgtcttg ctttagactt
      421 tgaaaattat agagaagctg aacgcatgat tgctcttgaa ctgctaggca atccaccaca
      481 gaaaatttga gtaagaatta agggcattat ttattgccaa tattccggta caaacaaagc
      541 ccatctcaat ctcattaagc caatcccctt cacgggccta tcccacaatg agaacaaatg
      601 taaagtatgt tacaccatag ccaaataggg tggacaaacg ttgtttgcat cggcataata
      661 tatttatacc cattctggat tgaaacccat tttatgaatg gctcccaatg cccattagat
      721 ggtgaaccat aacatggatt tcgattaaga attggtatta ttaggtaaac tatagatgtt
      781 cagaagttgt ttggtacaca ttattgaatg atagcatttc aatcaatagg agaaaaaata
      841 gatgactcaa atcatgacag aaatcgtgag cggtgaaccc tatcaatatt atcccctcag
      901 tgacaatatt gtacgatcaa tcggagtttg tggaaaaaga agtccaacct gaatttttaa
      961 aactaaaatt tttggggcgc ttatggtttg gtacggatga aatcatggat aaatgaattg
     1021 aaaattgaac agattgattt ctattactct caaagaaatg gattcttatt ttgccatcgt
     1081 gcccaaaagc gtcgtaaaaa ataaaattta tctaaatttc tgaactcatg aactcatgaa
     1141 cacctaacca ctgtatcaaa tcgaaaaagt cacggggaaa agcccgatgt agggtgggta
     1201 acgtgttttt gttgcccacc aaatctattt cacatttcac ttaacaagtt tacttataac
     1261 gtgaaataat gtttttgtgt gcaaaaacag aagcgtgaaa tatcaaaaag tttaagctat
     1321 gctcatgtgc agtataatag tctaatagac atgttaaaat attaatgtgt accaagtgta
     1381 tctatcaact atttgaagcg caggtagaac tagatgcgtg cgaggctaat aaaatgatgc
     1441 cacaaaaaaa acaattcact tgctttatga ttggagaagg cactttagtt attcaatgtg
     1501 ctaaacacat tttagaacaa gcgcatcaga tattgggtat gatttctcat gatgaagcgg
     1561 taacacactg ggcgaacagg aagggcatac cgtgcatcca agcaactgat aagctcatag
     1621 actttttaag tcagcagcct tttgattacc tatttagtat tattaacttt tctgtcttac
     1681 ccaaagatat tttgctatta ccgcgccagt atgccattaa ttatcatgat gcacctttgc
     1741 caaaatatgc gggtattaac gcgacttctt ggggtatcat taatcaggaa aaaacatggg
     1801 gtgtgacttg gcatatcatg agtgaacgaa ttgatggggg ggatatattg aagcaaaccc
     1861 ctatcgaaat agctcagaac gagactgctt ttacccttaa tctcaagtgc tatgaagcgg
     1921 ctattcattc atttaagcaa ctcagtgatg aactttcttg tgatcaagtc gtcgcaaggc
     1981 cacaaaaagt agaagaacgt agttattttt cgcgttttaa taaatccagt aaaggatgct
     2041 tactttcatg gaaccgtaaa gcccatgaga tagatgcctg ggttcgggct ttggactttg
     2101 gttcttctcc taatccactc gggttggcga aattttggct cggaagtgat tttgtcatca
     2161 tgaataaaat agatgttctt gatgccttat caacatcacc tcctggaacc ataacagcta
     2221 ttgatgataa cggtataaag gttgctaccg cgagtgacga tgtcacactg cgtcaagtga
     2281 aaactattga agggcaaaca ctctcaatcc ctgatttcgt gacgaaattt ggcctacatg
     2341 aaggatatca atttaaggag attaatccaa atctagcaaa acgtattgag cattttgatg
     2401 ccttgctcgc caaacacgag gcattttggg tagaacggct ggcaacatta cagcccatta
     2461 cgatccctta tatcactcaa agtgcctcgc cgttgaagcg gcaaagaacc tttaaaacga
     2521 tagaaatacc aatgccaact gaggtgacaa atttcctcaa tgaatgtcat accacttggc
     2581 ataaaagcga ttttatgttg gttgcttttg ttgcttatct ttcccgtatt ggagacaagc
     2641 ccagttttga tattggattt aaagatgtgg aattgcaaac tgaactggca ggaattgaag
     2701 gtttattggc ctcgtataaa ccttgtcgta tcacagtgga accggaaaac cgttttgata
     2761 aaatttttga tgccgtacaa gagcagatag cgttggttaa acgccacaag acttatatac
     2821 gcgatatagt cattcggtat ccggtacttg cttccaaagc agaattgcga aacgagcctt
     2881 tatatcctgt catcatagaa cgagtcgaaa aacgggaaaa ccacaaaata ggattgggtt
     2941 atgacttgag cttaatcatt caagaaaatg accaaaaatg ctattggttt tatgatacag
     3001 cagtattaga tgatgacagc ataacaagga tgttagggca attgacggct tttatgcaag
     3061 gcattgtcac ccatagtgct aaacgcatca gtgaatttcc cctgttatct gaacaagagc
     3121 gtcatcaaat cttagtagaa tggaataata cccaagtaga ttacccaaag gatgtctgtc
     3181 tccaccaatt gtttgaagct caagtagaac gaacaccaga cgctgtagca ctcgtttttg
     3241 aaaataaaca attgagttat cgtgaattga atcaacgcgc caatcaattg gcacatcatt
     3301 taatcaactt gggtgtgaaa ccggaaacat tggtaggtat ttgtatagaa cgttccttag
     3361 agatggttgt aggattgtta ggtatcctca aggcgggggg ggcatattta ccgctagagc
     3421 ccacctatcc gaacgttcgt ttagcattta tgttagaaga tgctcaagtg tctgtgttat
     3481 taactcaaga aaaattaatt aagaaattac ctgatcatat agaacatatt atttgcttag
     3541 ataccgattg gaaaattatc tctctattga gttgggaaaa tccaattagt ggtgtttcac
     3601 ccaagaactt ggtttatgtg atttatacat cgggttctac tggaaaacct aaaggggttt
     3661 tgctcaatca ttataatgtc gtgcgtcttt ttaaagccac taactcttgg tttcacttta
     3721 gtgaacaaga tgtgtggacg ttatttcatt cattagcttt cgatttttca gtatgggaac
     3781 tatggggggc ctttttctac ggtggatgtc ttgtaatcgt tccctattgg gtgagtcgtt
     3841 caccgcaaca attttacgag ctactatata cagagcaggt gactatcctc aatcagacac
     3901 cagcggcctt ccagcaactg attcggataa aagactcttc aaaaatattt caagcattaa
     3961 accttcgttt tatcatattc ggtggcgaaa gccttgattt caacacttta aaacattggt
     4021 ttgaacaaca tggtgatgag tatcctcagt taatcaacat gtatggtatt acagaaacaa
     4081 cggtacatgt cacttatcat cctataaaaa tggcagagat tggaaaagga agtataattg
     4141 gttgtccgat tcatgatcta caggtttata ttttggagaa taatttacaa ccagtaccta
     4201 ttgggattgt cggtgaaatg tatattggtg gggctggttt ggctagaggc tatcttaacc
     4261 gtcctgaact gacggctgaa aaattcattc ccaatccttt caataacgat ccaaaagcac
     4321 gtctttacaa aactggcgac ttagcccgct atttacccga tggcaatatt gaatatttgg
     4381 gcagaattga taatcaagtc aaaatgcgtg gttttcgcat tgagttggga gaaattgaaa
     4441 ccctactgaa tcaagattcg actgtgctgg aggctgtggt gattgcgcgt gatgatgaat
     4501 ctggtcatca gcgtttgatt gcttatattg tttctaaatt gattcttgaa cgtttacccc
     4561 taaaaaccag ttgcctcgtt gaattggatc atcaatctcc gataacgtta acgacagaag
     4621 acatttcttg tgagggggtt tgcttagtag gtgttcccca aactttggaa acgggtcaac
     4681 acgtccgtat acgtcgtcta caattgcccg atatatctga tgatcaactc gggttagaag
     4741 gccatattgc ttggtgccaa ggacaacggg ccggtatcca atttgccttc acgaatctta
     4801 gcacacgagt gcatttttgc caaatcatag ataatctctt tgaaactcaa ggtattataa
     4861 aggtcatgca acgcacctct agcgcacatc ttcgtgacgt tttacgccag aaattgcccg
     4921 actatatgat accgtctagt tttatttttt tgaaagctat tccattaacc cctaacggca
     4981 aagtagatcg taaagcactg cctcaacttg atgggcaacg tgcagattta gaaaccgcat
     5041 accttgctcc cgaaactgag attgaacaga aaatagcgcg tatattgcaa acggtgttgc
     5101 aggtaaacca agttggaata catgataact tctttgactt gggaggcaat tccttactgt
     5161 tggtacaagt gcaagaaaaa ttggtcgagg tattaaaccg agaggtgccc gttctcacac
     5221 tttttcagta ccccaccatc aatgccttgc ttcattattt agaagaagac tctcctagtg
     5281 agcagatggc tcttaaaaag agttatgatc gtgcccacaa ggcaaaatct gctgtacatc
     5341 aatttcgtaa acatcacaaa gcctgagtac tataaaacta taaaaaaatg aacatctggt
     5401 gaaaaagaaa gagtttttct aacgcttcgc gttgttcact tgggatgaaa ataccaaatt
     5461 aacgtagggt gggtaacgtc tttttgttgc ccaccttaaa tttaatcatc gaaggaaaaa
     5521 tccattatcc tcggtataaa tggggctgca aaaacacgct acccacccta cgttgaacat
     5581 tgaagtaata ttaacaatat ctaatatata ataaattcaa gaacttatct atcatctttt
     5641 ttactgacat aacaggaaaa agatatgaaa acagccactt ttaaagaatg gactttgacc
     5701 acacttgata aggcctttgg gctttgtcaa atttgggaat gcgccttaat ggacaactgg
     5761 gaaaatcaag agattgaaat agacgatttc gagaaaaaaa ccctgctcaa cctacaaaaa
     5821 catcagatta gagggggtag ggcttggaac gaggttgaac ttgaaaataa gtttattagt
     5881 ccggttatca tgacagccaa tatcgacgat gagcagattg gctatttttt agaacgtcgt
     5941 ttatcaggta tcgtgggtga ttatgaactg tccggcatcg tagatggcat gattgcgaca
     6001 ggttttcgtg atcctgatat ccccctgttt tgtctgcacg aatacaaaca tcgctgcgat
     6061 aatcaaggtt cacccgacgc acaagcgctt gctgctatgt tagtcgccag agaacagaat
     6121 gataatcaaa aagcaatcta tgatgtattt gtggttggct tggtttggaa ttttatgatt
     6181 ttaaatggca atgagtattt tattagcaaa acctatcatg ccgatgaaga agaaattttt
     6241 gcgattttca aaatgctcaa agtcttaaaa aagattatta aagataactt gattaactag
     6301 tgcaagagag cgaaaatatc gagaaccttc agccaacagc ttttcacgcc aaagattttg
     6361 cgcgcaaaat ctttggcgtg aaccggaggt cagcgaagct aaagcagttg tctaaaagct
     6421 taagtcacct aaaggtgact a
//
