LOCUS       c00263_3300014..        7263 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300014869.a:Ga0180298_1000916.
ACCESSION   c00263_3300014..
VERSION     c00263_3300014..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 06:54:14
            Original ID  :: 3300014869.a:Ga0180298_1000916
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7263
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..7263
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[388:7261](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(389..7261)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..7263
                     /SMILES="NC(C(O)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..7263
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             complement(389..7261)
                     /NRPS_PKS="Domain: PCP (223-290). E-value: 5.6e-22. Score:
                     69.5. Matches aSDomain: nrpspksdomains_ctg263_1_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (310-613). E-value:
                     2.4e-115. Score: 376.4. Matches aSDomain:
                     nrpspksdomains_ctg263_1_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (777-1185). E-value:
                     1.1e-115. Score: 378.3. Matches aSDomain:
                     nrpspksdomains_ctg263_1_AMP-binding.1"
                     /NRPS_PKS="Domain: nMT (1280-1503). E-value: 8.1e-117.
                     Score: 381.8. Matches aSDomain:
                     nrpspksdomains_ctg263_1_nMT.1"
                     /NRPS_PKS="Domain: PCP (1730-1797). E-value: 1.3e-26.
                     Score: 84.4. Matches aSDomain:
                     nrpspksdomains_ctg263_1_PCP.2"
                     /NRPS_PKS="Domain: Epimerization (1807-2120). E-value:
                     6.7e-137. Score: 449.0. Matches aSDomain:
                     nrpspksdomains_ctg263_1_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (2126-2279). E-value: 1.7e-51.
                     Score: 165.8. Matches aSDomain:
                     nrpspksdomains_ctg263_1_TIGR01720.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     352.9; E-value: 3.8e-107)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg263_1"
                     /sec_met_domain="Condensation (E-value: 9.1e-83, bitscore:
                     263.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 9.8e-129, bitscore:
                     415.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7.3e-19, bitscore:
                     54.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="NKEGDNKEGDNKEGEHVGGKHVEGEHVGSPLHQSLVVNVKDRFGD
                     YGLVGLMLFEYDADALIVDTFLLSCRALGRGVEHNMLAQLGKIATERQISQIKIRYNPT
                     SKNQPVRDFLESVTSPLQQSVKPGWHALPAEYVAKLTYRPASIEKPSSPKSLLIPTANE
                     KASQTTRIGYNKGLDRGISLFYKIATECFDAEQILKTIESQKTHQRPKLVTAYVAPRNP
                     VEDMLVGIFKTLLNIEQVGIHDNFFQLGGHSLLGVQVMSRIRDIFSVELPLHYLFEYPN
                     VIGLSEQIQLAQRDNTKSLCPPIQPIERQGPLPLSFPQERLWFLDQLTPDNPFYNTPAA
                     VRLDGHLDITALEQSIRAIAQRHETLRTCFKTINGKPVLVIHPLSVNHYQFSIINLQKL
                     PEEKQSEQVQHLTDIEAQRPFDIQQGPLFRTTLIQLNAEQHVFLMTIHHIITDGWSMGI
                     LVQELSALSEAFSTGSPSPLPELPIQYVDFAQWQRQWLTGEVLATHLNYWQQQLADAPP
                     VLEIPSDHPRPPVHTFRGRSQYFEIPPELTQQLKTLSQQSGVTLFMISLAAFAILLERY
                     SGQEDILIGSPIANRTRQEIEPLIGLFVNILVLRLDLSGEPTFIDLLTQVREVTLGAYA
                     HQDLPFEKLVEALQPERDMSRNALVQVALAFQNVPQPPIKLIDFTITPVEFEAGTVRFD
                     LEFHLWETADQLVGRFFYYQDMFEAATIARLLKHFHTLLTEIVAQPDKPISELSLLSQA
                     ERHQLLLDWHHSTSYPAEPCIHQGFENQAARTPNHIALVFEEQSVTYQALNTRANQLAH
                     YLQTQGIQPDRLVGLCVERSLEMVIGLLGILKAGGAYLPLDPSSPPERLLFILEDAKIT
                     LLLTQEALVTELPTTPIALICLDSQWDMIAQGASENPLSAVKPDNVAYVIYTSGSTGKP
                     KGVEVCHANVARLLTATQAWFHFNEQDIWTLFHSYAFDFSVWELWGSLLYGGRLVIVPY
                     WISRSPDSFYELLVSQQVTILNQTPSAFRQLIQAEERVGKPNDNLTLRQIIFGGEALDF
                     QTLKPWFERHGDQTPQLVNMYGITETTVHVTYRPLTQADLNSPGSLIGIPIPDLHIYIL
                     DRHRQPTPIGIPGELYVGGAGVARGYLNRPQLTTERFIKNPFSDEPNARLYKTGDLARY
                     LADGSLEYLGRIDLQVKIRGFRIELGEIETVLLQHTAVREAVITSSTVSNEEENKRLMA
                     YVVPDFDDPSQMADDVADQSELINQWEDVFDENYGQPDTVADPSFNIAGWNSSYTGLPI
                     PPAEMREWVDAAVNAILSLKPKRVLEIGCGTGLLLSRIAPHSQQYWGTDFSPVVLQQVE
                     QLKHQIKPLEHVKLFQRPADDFNDIAPGTFDTIILNSVIQYFPSIDYLIKVLDQAIQVV
                     QPGGAIFLGDIRSLPLLKAYHASVQGYQAPDSLNQSALRQQVQQHIAQEVELVIDPAFF
                     IALKQHYPQLSTVQIQLKRGCYHNELSRFRYEVILQVGDTAPTVEIAWQEWQNQPFTLD
                     SILQRLQGNQGNSETPEASRETLQAETQSPQGQSFGVRGVPNARLETEIKTLEWLANAA
                     PTETVGELQETLSTHQPIGIDPEDLWQLTDNSPYEVIITWSDTIGCYDVLFRHHHDPLA
                     ITPYPISPEPFKKPWHQYANNPLQQKLNRKLVPQLRQYLQDQLPDYMVPAAFVMLEVIP
                     LTANGKIDYRALQTLDISTNKADKEQVAPRTSTENLLATIWAEVLGLEQVGIHDNFFES
                     GGDSILSIQIVARANQAGLQLTPRLLFQHQTIAELAEVASTALIQAEQGIVTGPVLFTP
                     IHHWFLEQNGQAAHHFNQAVLLAGPTEPNRAWLAEIVQQWLSHHDIFRLRLTRNESDWQ
                     ATQIDLNSEDSLPFQVINLSELATHQQFQALETAANQQQASLNLSKGPLLRVILFELGP
                     TTPSRLLIVIHHMAIDGVSWRILLEELQTAYQQLSQDEAIQWPAKTTSFKAWSERLSEY
                     AQSVTVTAELNHWLSFSEITPLPVDFSPELTSSTEYSTSNTVASSAQITVSLTVEETHA
                     LLNEVPSVYNTQINDILLTALVQSLSRWTTNHELVIDLEGHGREDLFENSDLSRTVGWF
                     TSIYPVLLTLDNANSPSDTLKSIKEQLRHIPNRGIGYGLLRYLNPKTAWQLKMLPQPEI
                     SFNYLGQFDNQLSDDILFKMAQENSGKTHSPSEQRRYLIEINGLITENQLQLEWTYSQN
                     RHHRATIEQLAHDFIAALQTLITHCKSQKTGDYTPSDFLSSKLSQNSLDKLMKKLGAKS
                     NKK"
     aSDomain        complement(425..883)
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg263_1_TIGR01720.1"
                     /evalue="1.70E-51"
                     /label="ctg263_1_TIGR01720.1"
                     /locus_tag="ctg263_1"
                     /protein_end="2279"
                     /protein_start="2126"
                     /score="165.8"
                     /tool="antismash"
                     /translation="SDTLKSIKEQLRHIPNRGIGYGLLRYLNPKTAWQLKMLPQPEISF
                     NYLGQFDNQLSDDILFKMAQENSGKTHSPSEQRRYLIEINGLITENQLQLEWTYSQNRH
                     HRATIEQLAHDFIAALQTLITHCKSQKTGDYTPSDFLSSKLSQNSLDKLM"
     CDS_motif       complement(803..865)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg263_1_0012"
                     /evalue="2.40E-11"
                     /label="NRPS-E6"
                     /locus_tag="ctg263_1"
                     /protein_end="2153"
                     /protein_start="2132"
                     /score="35.6"
                     /tool="antismash"
                     /translation="IKEQLRHIPNRGIGYGLLRYLN"
     aSDomain        complement(902..1840)
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg263_1_Epimerization.1"
                     /evalue="6.70E-137"
                     /label="ctg263_1_Epimerization.1"
                     /locus_tag="ctg263_1"
                     /protein_end="2120"
                     /protein_start="1807"
                     /score="449.0"
                     /tool="antismash"
                     /translation="TGPVLFTPIHHWFLEQNGQAAHHFNQAVLLAGPTEPNRAWLAEIV
                     QQWLSHHDIFRLRLTRNESDWQATQIDLNSEDSLPFQVINLSELATHQQFQALETAANQ
                     QQASLNLSKGPLLRVILFELGPTTPSRLLIVIHHMAIDGVSWRILLEELQTAYQQLSQD
                     EAIQWPAKTTSFKAWSERLSEYAQSVTVTAELNHWLSFSEITPLPVDFSPELTSSTEYS
                     TSNTVASSAQITVSLTVEETHALLNEVPSVYNTQINDILLTALVQSLSRWTTNHELVID
                     LEGHGREDLFENSDLSRTVGWFTSIYPVLLTLD"
     aSModule        902..6331
                     /complete
                     /domains="nrpspksdomains_ctg263_1_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg263_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg263_1_nMT.1"
                     /domains="nrpspksdomains_ctg263_1_PCP.2"
                     /domains="nrpspksdomains_ctg263_1_Epimerization.1"
                     /locus_tags="ctg263_1"
                     /monomer_pairings="thr -> D-NMe-thr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(908..958)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg263_1_0011"
                     /evalue="3.20E-09"
                     /label="NRPS-E5"
                     /locus_tag="ctg263_1"
                     /protein_end="2118"
                     /protein_start="2101"
                     /score="28.7"
                     /tool="antismash"
                     /translation="DLSRTVGWFTSIYPVLLT"
     CDS_motif       complement(1382..1447)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg263_1_0010"
                     /evalue="1.10E-10"
                     /label="NRPS-E2"
                     /locus_tag="ctg263_1"
                     /protein_end="1960"
                     /protein_start="1938"
                     /score="33.7"
                     /tool="antismash"
                     /translation="LLIVIHHMAIDGVSWRILLEELQ"
     aSDomain        complement(1871..2071)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg263_1_PCP.2"
                     /evalue="1.30E-26"
                     /label="ctg263_1_PCP.2"
                     /locus_tag="ctg263_1"
                     /protein_end="1797"
                     /protein_start="1730"
                     /score="84.4"
                     /tool="antismash"
                     /translation="ENLLATIWAEVLGLEQVGIHDNFFESGGDSILSIQIVARANQAGL
                     QLTPRLLFQHQTIAELAEVASTA"
     aSDomain        complement(2753..3421)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg263_1_nMT.1"
                     /domain_subtype="nMT"
                     /evalue="8.10E-117"
                     /label="ctg263_1_nMT.1"
                     /locus_tag="ctg263_1"
                     /protein_end="1503"
                     /protein_start="1280"
                     /score="381.8"
                     /tool="antismash"
                     /translation="GLPIPPAEMREWVDAAVNAILSLKPKRVLEIGCGTGLLLSRIAPH
                     SQQYWGTDFSPVVLQQVEQLKHQIKPLEHVKLFQRPADDFNDIAPGTFDTIILNSVIQY
                     FPSIDYLIKVLDQAIQVVQPGGAIFLGDIRSLPLLKAYHASVQGYQAPDSLNQSALRQQ
                     VQQHIAQEVELVIDPAFFIALKQHYPQLSTVQIQLKRGCYHNELSRFRYEVILQVGDTA
                     PT"
     CDS_motif       complement(3293..3328)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg263_1_0009"
                     /evalue="1.50E+01"
                     /label="C3_starter_134-155"
                     /locus_tag="ctg263_1"
                     /protein_end="1323"
                     /protein_start="1311"
                     /score="-1.0"
                     /tool="antismash"
                     /translation="GCGTGLLLSRIAP"
     CDS_motif       complement(3677..3742)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg263_1_0008"
                     /evalue="2.10E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg263_1"
                     /protein_end="1195"
                     /protein_start="1173"
                     /score="35.8"
                     /tool="antismash"
                     /translation="YLGRIDLQVKIRGFRIELGEIET"
     aSDomain        complement(3707..4930)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg263_1_AMP-binding.1"
                     /evalue="1.10E-115"
                     /label="ctg263_1_AMP-binding.1"
                     /locus_tag="ctg263_1"
                     /protein_end="1185"
                     /protein_start="777"
                     /score="378.3"
                     /specificity="consensus: thr"
                     /tool="antismash"
                     /translation="FENQAARTPNHIALVFEEQSVTYQALNTRANQLAHYLQTQGIQPD
                     RLVGLCVERSLEMVIGLLGILKAGGAYLPLDPSSPPERLLFILEDAKITLLLTQEALVT
                     ELPTTPIALICLDSQWDMIAQGASENPLSAVKPDNVAYVIYTSGSTGKPKGVEVCHANV
                     ARLLTATQAWFHFNEQDIWTLFHSYAFDFSVWELWGSLLYGGRLVIVPYWISRSPDSFY
                     ELLVSQQVTILNQTPSAFRQLIQAEERVGKPNDNLTLRQIIFGGEALDFQTLKPWFERH
                     GDQTPQLVNMYGITETTVHVTYRPLTQADLNSPGSLIGIPIPDLHIYILDRHRQPTPIG
                     IPGELYVGGAGVARGYLNRPQLTTERFIKNPFSDEPNARLYKTGDLARYLADGSLEYLG
                     RIDLQVKIRG"
     CDS_motif       complement(3830..3919)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg263_1_0007"
                     /evalue="2.50E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg263_1"
                     /protein_end="1144"
                     /protein_start="1114"
                     /score="54.9"
                     /tool="antismash"
                     /translation="PIGIPGELYVGGAGVARGYLNRPQLTTERFI"
     CDS_motif       complement(4451..4510)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg263_1_0006"
                     /evalue="2.00E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg263_1"
                     /protein_end="937"
                     /protein_start="917"
                     /score="29.5"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGKPKGVEVCHA"
     CDS_motif       complement(4703..4744)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg263_1_0005"
                     /evalue="2.50E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg263_1"
                     /protein_end="853"
                     /protein_start="839"
                     /score="17.5"
                     /tool="antismash"
                     /translation="LGILKAGGAYLPLDP"
     CDS_motif       complement(5264..5383)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg263_1_0004"
                     /evalue="3.10E-23"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg263_1"
                     /protein_end="666"
                     /protein_start="626"
                     /score="74.3"
                     /tool="antismash"
                     /translation="REVTLGAYAHQDLPFEKLVEALQPERDMSRNALVQVALAFQ"
     aSDomain        complement(5423..6331)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg263_1_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="2.40E-115"
                     /label="ctg263_1_Condensation_LCL.1"
                     /locus_tag="ctg263_1"
                     /protein_end="613"
                     /protein_start="310"
                     /score="376.4"
                     /tool="antismash"
                     /translation="GPLPLSFPQERLWFLDQLTPDNPFYNTPAAVRLDGHLDITALEQS
                     IRAIAQRHETLRTCFKTINGKPVLVIHPLSVNHYQFSIINLQKLPEEKQSEQVQHLTDI
                     EAQRPFDIQQGPLFRTTLIQLNAEQHVFLMTIHHIITDGWSMGILVQELSALSEAFSTG
                     SPSPLPELPIQYVDFAQWQRQWLTGEVLATHLNYWQQQLADAPPVLEIPSDHPRPPVHT
                     FRGRSQYFEIPPELTQQLKTLSQQSGVTLFMISLAAFAILLERYSGQEDILIGSPIANR
                     TRQEIEPLIGLFVNILVLRLDLS"
     CDS_motif       complement(5432..5521)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg263_1_0003"
                     /evalue="3.30E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg263_1"
                     /protein_end="610"
                     /protein_start="580"
                     /score="51.6"
                     /tool="antismash"
                     /translation="DILIGSPIANRTRQEIEPLIGLFVNILVLRL"
     CDS_motif       complement(5864..5926)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg263_1_0002"
                     /evalue="1.50E-11"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg263_1"
                     /protein_end="466"
                     /protein_start="445"
                     /score="36.6"
                     /tool="antismash"
                     /translation="IHHIITDGWSMGILVQELSALS"
     CDS_motif       complement(6152..6265)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg263_1_0001"
                     /evalue="1.40E-18"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg263_1"
                     /protein_end="370"
                     /protein_start="332"
                     /score="59.3"
                     /tool="antismash"
                     /translation="PFYNTPAAVRLDGHLDITALEQSIRAIAQRHETLRTCFK"
     aSDomain        complement(6392..6592)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg263_1_PCP.1"
                     /evalue="5.60E-22"
                     /label="ctg263_1_PCP.1"
                     /locus_tag="ctg263_1"
                     /protein_end="290"
                     /protein_start="223"
                     /score="69.5"
                     /tool="antismash"
                     /translation="EDMLVGIFKTLLNIEQVGIHDNFFQLGGHSLLGVQVMSRIRDIFS
                     VELPLHYLFEYPNVIGLSEQIQL"
     aSModule        6392..6592
                     /domains="nrpspksdomains_ctg263_1_PCP.1"
                     /incomplete
                     /locus_tags="ctg263_1"
                     /tool="antismash"
                     /type="unknown"
ORIGIN
        1 agcagagccg acaaaaaacc cgagacgtga agcatcgcgt ctcgggtttt ttgtagaggg
       61 tttttttgta gatttgctct gcttcgcgtc tcgggttttt tgtcggctct gcttcgcgtc
      121 tcgggttttt tgtagagggt ttttttgtag atttgctctg cttcgcgtct cggttttttt
      181 gtagagacgt gatgcttcac gtctctcgtt ttttgtagag acgcgatgct tcgcgtctct
      241 cgttttttgt aggctctgcg aagcgtctct cgttttttgc agagacgcga agcatcgcgt
      301 ctctacaggc agcttctatt aaaatacctg aaaatttatg gttcagtact taacgatggc
      361 aaactaaagt tggaaggctg gctttgagtt attttttatt tgatttcgcg cctaatttct
      421 tcatcagttt gtcgagactg ttttggctta attttgaact gaggaagtcg gaaggggtgt
      481 agtcccccgt tttttgtgat ttacagtggg taatcagggt ttgtaaggcc gctatgaaat
      541 cgtgtgctaa ttgttcaatg gtggcacgat gatggcggtt ttggctgtaa gtccattcga
      601 gttgtaattg attttcggtt attaagccat tgatttctat taaataacga cgttgttctg
      661 atgggctatg tgttttacca ctgttttctt gagccatttt aaagagtatg tcatctgata
      721 attgattatc aaattgaccc agatagttaa aagagatttc tggttgaggg agcattttta
      781 gctgccaagc ggtttttggg tttaagtaac gtaatagccc ataaccgata ccgcggttag
      841 gtatgtgacg caattgttct ttgatggatt ttagggtgtc gctgggtgag tttgcgttat
      901 ccagtgttaa cagtacgggg taaatactgg taaaccaacc gactgtgcgt gataaatcac
      961 tgttttcaaa taagtcttcg cgcccatgcc cttctaaatc aatgactagc tcgtggtttg
     1021 tcgtccagcg gctcaaactc tgtactaaag cggttagcag tatatcgttg atttgtgtat
     1081 tgtagacgga gggaacttcg ttcaataagg cgtgggtttc ttcaaccgtt aaagaaacgg
     1141 tgatttgtgc gctggaggcg acggtattgc tcgttgaata ctcggtggat gatgttaact
     1201 ctggggagaa gtcaactggc aaaggggtga tctcgctaaa tgaaagccag tggtttaatt
     1261 cggctgtgac tgtcaccgat tgggcatatt cgctgagccg ttctgaccaa gctttaaaag
     1321 aggtggtttt ggctggccat tgaatggctt catcttggct gagttgttgg taggcggttt
     1381 gcaactcttc taacaaaatg cgccaagata cgccgtcaat tgccatatga tggatgacga
     1441 tgagcaaacg gctgggggtt gtggggccga gttcaaataa aatgacgcgc aataaggggc
     1501 ctttggagag attgagactg gcttgttgtt gattggcggc cgtttctagg gcctggaact
     1561 gttgatgggt tgccaattcg gataaattga tgacttgaaa gggcaagctg tcttctgagt
     1621 ttaagtctat ctgtgtggct tgccaatctg attcattgcg cgtcaatcgt agacgaaaga
     1681 tatcgtgatg gctaagccac tgttgcacga tttccgctaa ccaggcccga ttgggttcgg
     1741 ttgggccggc aagcagtacg gcttgattga agtggtgagc ggcttgcccg ttttgttcta
     1801 aaaaccaatg gtgtatgggt gtgaagagta ctgggcccgt gactatgcct tgttctgctt
     1861 gaatcaaggc tgtgctggcg acttcagcca attctgcaat cgtttgatgt tgaaagagta
     1921 atcggggtgt gagttgcaat ccggcttgat tggctctggc aacgatttga atactgagga
     1981 tcgagtcgcc accgctttca aagaaattgt cgtgaatacc gacttgttct aaacccagta
     2041 cctcggccca aatcgtggct aataggtttt cagttgaggt gcgcggtgct acttgttctt
     2101 tatcggcttt gttggtggag atatctaagg tttgaagcgc acggtagtca attttgccat
     2161 tggcggttaa ggggatgact tctaacatca caaaggcggc cggtaccatg taatcaggta
     2221 gctgatcttg tagatattgc cgtagttgag gcactaattt gcgattcagt ttctgttgta
     2281 atgggttatt ggcgtactga tgccaaggtt ttttaaaggg ttcagggcta atgggataag
     2341 gggtgatggc taatggatcg tgatgatgtc tgaataagac atcatagcag ccaatggtat
     2401 cgctccaagt gataatgact tcataaggtg agttgtctgt gagttgccat aagtcttcag
     2461 gatcgatgcc gatgggctga tgtgtggaaa gggtttcctg tagttcacct accgtttcag
     2521 tgggcgcggc gttggcaagc cattctaagg ttttgatttc tgtttccaga cgcgcattgg
     2581 gtacccctcg cacgccaaaa ctttggccct gaggggactg cgtttccgct tgaagcgttt
     2641 ctcttgaagc ttcgggcgtt tcactatttc cttgatttcc ttgtaatcgt tgcagaatac
     2701 tgtctaatgt aaagggttgg ttttgccact cttgccaggc gatttctaca gtcggcgcgg
     2761 tgtcacccac ttgcaaaatc acttcataac gaaatcggct cagttcatta tgataacaac
     2821 ctcgtttcaa ttgaatttgt acagtgctca actgaggata atgttgtttt aaggctatga
     2881 aaaaagcggg atcaatgact aattcaactt cttgggctat atgttgttgc acttgttgcc
     2941 gtaaggcgga ttgattgagc gaatcgggtg cttgatagcc ttgaacagaa gcatgataag
     3001 ctttgagcag cggtaaacta cgaatgtcac cgaggaaaat agcgccaccg ggttgcacta
     3061 cttggatggc ctgatctaat accttgatca ggtagtcaat gctgggaaaa tactgaatga
     3121 ctgaattgag aataatggtg tcaaaagtgc cgggtgcgat atcgttaaaa tcatcggccg
     3181 ggcgttgaaa cagcttgaca tgttctagcg gtttgatttg atgcttgagt tgctcaactt
     3241 gttgcaagac gacgggggaa aaatcggttc cccaatattg ttggctatgc ggtgcaatac
     3301 gggataacaa taagcctgtg ccgcaaccga tttccaaaac acgcttgggt tttaaagaca
     3361 gaatggcatt gacggcggcg tcaacccatt cgcgcatttc tgctggcggg atgggtaaac
     3421 cggtatagct actattccag ccggcaatat taaagctggg atcggctacg gtatcgggtt
     3481 ggccatagtt ttcatcgaaa acgtcttccc attggttaat gagttcactt tgatcagcga
     3541 catcatcagc catttggctg ggatcatcaa aatcaggcac cacataagcc attaaccgct
     3601 tattttcttc ttcgtttgaa actgtggagc tggtgattac tgcttctcgt actgcggtgt
     3661 gttgcaacaa tacggtttca atttctccta attcaatacg aaaaccccgt attttgactt
     3721 gtagatcgat gcggcctaaa tattcaagac tgccatcggc taaataacgc gccaagtctc
     3781 ccgttttata gagacgtgca ttgggttcat cactaaacgg gtttttgata aatcgctctg
     3841 ttgtgagttg aggccggttg aggtagccgc gagccacgcc ggcaccgccg acgtataatt
     3901 ctcctggaat cccgataggg gttggttggc gatgacgatc cagtatgtaa atgtgtaaat
     3961 cgggaatcgg tatgccaatc agactgcctg gagaattgag atcggcttgc gtgagtggac
     4021 gataagtgac atgtacggtg gtttcggtga taccgtacat attcactaat tggggcgttt
     4081 gatcaccatg tcgttcaaac caaggtttta aggtttgaaa gtctagggct tctccaccaa
     4141 agatgatttg tcgtaacgtt aaattgtcat tgggttttcc aacacgttct tcggcctgaa
     4201 tcagttgacg aaaggctgat ggggtttggt tgagaatcgt cacctgttgg ctgacaagca
     4261 attcgtagaa gctgtcaggt gagcggctta tccagtaggg aacgatgact aagcgaccgc
     4321 catagagcag ggagccccac agttcccaaa cggaaaaatc aaaggcataa gaatgaaata
     4381 gggtccaaat atcttgttca ttaaagtgaa accaagcttg agtggctgtc aataaacgcg
     4441 ccacattcgc atgacacact tcaacgccct tgggtttgcc ggttgaacct gaggtataaa
     4501 tcacgtaggc gacattgtca ggtttgacag cactcaaggg attctctgaa gcgccctgag
     4561 caatcatgtc ccactggcta tcgagacaaa tcagcgcaat gggtgttgtt ggcagttctg
     4621 tgactaacgc ttcttgcgtg agcaatagcg tgattttcgc atcttctaat ataaaaagca
     4681 gccgttcagg aggagaactg ggatctaaag gcagataggc tccgcccgct ttgagaatac
     4741 ccagtagccc gatcaccatt tccaaagaac gttcgacaca taagccaacc agcctatcgg
     4801 gttgaatccc ttgtgtttgc aaatagtggg caagttgatt ggctctggtg ttcaatgcct
     4861 gataagtcac agactgttct tcaaacacta gggcaatgtg attgggtgta cgggcggctt
     4921 ggttttcaaa cccttgatga atgcagggtt cggctgggta gcttgtgctg tgatgccaat
     4981 ctagcaatag ttgatgtcgt tctgcttggc tgagcaatga taattctgaa ataggcttgt
     5041 caggctgtgc aacaatctct gtcaataagg tgtgaaaatg ttttaataac cgcgcaatgg
     5101 tggcggcctc aaacatgtct tgataataga aaaaacgccc gacaagttga tcagcggttt
     5161 cccacaagtg aaattctaaa tcaaatctga ctgtgccggc ttcaaattcc acaggggtta
     5221 tagtgaaatc gatcagtttg ataggcggtt gagggacatt ttgaaaagct aaggcgactt
     5281 gtactaaggc attgcgactc atatcccgtt caggctgcaa agcttctacc agtttttcaa
     5341 aaggcaaatc ttggtgagca taagcgccta gtgtcacctc tcgtacctga gtcagtaagt
     5401 caataaaagt gggttcccct gataaatcaa ggcgtaaaac gagtatattc acaaacaaac
     5461 ctatcagggg ttcaatttct tgtcgcgtcc ggttggcgat aggcgaacca atgagaatat
     5521 cttcctggcc gctatagcgt tccagtaaaa tagcgaaagc ggccagtgag atcataaaca
     5581 gtgtcacgcc agattgctga ctcaaggttt tgagttgctg ggttaattcg gggggaattt
     5641 caaaatattg gctgcgcccc cggaaagtat ggactggcgg acgtggatga tcactgggta
     5701 tttccaacac cggtggcgcg tctgctaact gttgttgcca ataattcagg tgtgtagcca
     5761 gcacttctcc tgtcaaccat tgacgttgcc actgtgcaaa atcgacatac tgaatcggta
     5821 attcgggtag aggagaaggg ctgccagttg aaaatgcctc cgacagggca gataattctt
     5881 ggactaaaat gcccattgac cacccatcag taataatatg atgaatcgtc atcaaaaaaa
     5941 catgttgttc agcgttcagt tgtatcaggg tggtacggaa taatggccct tgctggatat
     6001 caaagggacg ttgcgcctca atatcagtca agtgttgtac ttgttcagat tgtttctctt
     6061 ctggtagctt ttgtaaattg ataattgaaa attgataatg attgacagat agcggatgaa
     6121 tcactagcac cggtttaccg ttaatcgttt taaagcaggt tcgcaaggtt tcatgacgtt
     6181 gggcgattgc cctgatgctc tgttcaaggg cggttatatc taaatgccca tctaaacgca
     6241 cggccgctgg tgtattatag aaggggttat caggtgtcaa ttgatcgaga aaccataagc
     6301 gttcttgagg aaaagacagc ggtaatgggc cctgtcgttc aatcggttga attggggggc
     6361 ataatgattt tgtgttgtcg cgttgtgcca attgaatctg ttcgcttaac ccaatcacgt
     6421 taggatattc aaatagatag tgtaggggta attctaccga aaagatatca cgtattcgtg
     6481 acatcacttg aacccccaat aaggaatggc cgcctaattg gaagaaatta tcatgaatac
     6541 ccacctgctc aatattgagg agggttttaa aaataccgac taacatgtct tcaacagggt
     6601 tacgcggcgc gacataagcg gtcaccaatt taggcctctg atgagttttc tgagactcaa
     6661 tggtttttaa aatctgttca gcgtcaaagc actctgttgc aattttgtaa aatagggata
     6721 tcccacgatc caatccttta ttataaccaa tccttgtagt ttgactggcc ttttcattgg
     6781 cagtcggtat caaaagggat tttggtgaag acggtttttc tatactggca ggccgataag
     6841 ttaatttggc cacgtattcg gctggcaatg cgtgccagcc tggcttaacc gattgttgca
     6901 aggggctagt gacactttcc aagaaatcgc gtaccggttg atttttggaa gtcgggttat
     6961 agcgtatctt aatctggctg atctgtcgtt ctgtggcgat tttgcctaac tgagcgagca
     7021 tgttatgctc aacgcctcta cccaaggcgc ggcaactgag tagaaaggta tcgacgataa
     7081 gggcatccgc gtcatattca aataacatga ggccgactaa accataatcc ccaaaacgat
     7141 ctttcacgtt cacaaccaga gattgatgta ggggcgaacc tacgtgttcg ccctcaacgt
     7201 gtttgccccc gacgtgttcg ccctctttgt tatcgccctc tttgttatcg ccctctttgt
     7261 tat
//
