LOCUS       c00717_3300014..       11923 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300014869.a:Ga0180298_1000097.
ACCESSION   c00717_3300014..
VERSION     c00717_3300014..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 06:54:14
            Original ID  :: 3300014869.a:Ga0180298_1000097
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 4467
            Orig. end    :: 16390
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11923
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[9467:11390](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or
                     TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or
                     TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692
                     or TIGR01193)"
                     /neighbourhood="5000"
                     /product="bacteriocin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..6923
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or
                     TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or
                     TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692
                     or TIGR01193)"
                     /neighbourhood="5000"
                     /product="bacteriocin"
                     /protocluster_number="1"
     cand_cluster    1..11923
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or
                     TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or
                     TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692
                     or TIGR01193)"
                     /kind="single"
                     /product="bacteriocin"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11923
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="bacteriocin"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or
                     TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or
                     TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or
                     TIGR01193)"
                     /tool="antismash"
     CDS             1174..3426
                     /NRPS_PKS="Domain: AMP-binding (14-416). E-value: 1.4e-91.
                     Score: 298.9. Matches aSDomain:
                     nrpspksdomains_ctg717_5_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     313.2; E-value: 4.2e-95)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg717_5"
                     /sec_met_domain="AMP-binding (E-value: 5.9e-93, bitscore:
                     301.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLLYSMLTNAKAKAASKAFLTDIQNNEQYSYETLYDLTQSIRHL
                     LSDYKVVKGDRVAFVTRNEAMFYPLFFACSAVGAVLVPISPENHPSEIKSMLMDAKPKL
                     TFYGEGMEDLSILGKQRIALKKSNLPAITGEETLKCLPLSDEECYKDDDALIIYTSGTT
                     GNCKGIVLSQNNLYSMANAFATMYKYQENQRFLCILPFYHINAIMVTGLACVLSRAHIV
                     LSSLFGPLVGKFFWKIVSDNKIDVLSLTPSIMAMLLKLFPSGADHDISHVSHALVGTAP
                     LSKTLWKHFEDIFGIPCYQGYGLTETTTWATMTPMKEPRHFESVGLPISCCEIKIMEYD
                     SVGEVAYTQHQEMDNRDKKVGEILIRGDIVMKGYYNRKTFTKKNFFKGWFKTGDIGYFG
                     KDGHLYIVGRIKNIIKRKGITLFPEEVNDALREHENIVDCCAFGVEDELLGEKVILACL
                     VKDKEQEDVSEFRSYLRSRLSSHKLPDQYVIMREFPRTSMGKININELKSIVGGKRASE
                     VIKLLNIPKFRRANCENDSEINRLVQKSILSGEKLGMIAYWGGGKRSKLNKFDIGALDN
                     IEMIKVSINELMGRKSIDFTLILTDIHVKVNRVPTEIMEAYFAAIQSEAESREIKTIQL
                     SHIWEKSGLDFDAVVNSVNQPGFTEKWKRFGHQELFILQAEKRCSTSELAMVLAKQYFA
                     IVEAENTVIARLFADHIFFTYNDLSYKKFLPKLPTVHWYSHVDGNTKKSDKPWFTN"
     aSDomain        1216..2421
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg717_5_AMP-binding.1"
                     /evalue="1.40E-91"
                     /label="ctg717_5_AMP-binding.1"
                     /locus_tag="ctg717_5"
                     /protein_end="416"
                     /protein_start="14"
                     /score="298.9"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="AASKAFLTDIQNNEQYSYETLYDLTQSIRHLLSDYKVVKGDRVAF
                     VTRNEAMFYPLFFACSAVGAVLVPISPENHPSEIKSMLMDAKPKLTFYGEGMEDLSILG
                     KQRIALKKSNLPAITGEETLKCLPLSDEECYKDDDALIIYTSGTTGNCKGIVLSQNNLY
                     SMANAFATMYKYQENQRFLCILPFYHINAIMVTGLACVLSRAHIVLSSLFGPLVGKFFW
                     KIVSDNKIDVLSLTPSIMAMLLKLFPSGADHDISHVSHALVGTAPLSKTLWKHFEDIFG
                     IPCYQGYGLTETTTWATMTPMKEPRHFESVGLPISCCEIKIMEYDSVGEVAYTQHQEMD
                     NRDKKVGEILIRGDIVMKGYYNRKTFTKKNFFKGWFKTGDIGYFGKDGHLYIVGRIKNI
                     IKRK"
     aSModule        1216..2421
                     /domains="nrpspksdomains_ctg717_5_AMP-binding.1"
                     /incomplete
                     /locus_tags="ctg717_5"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       1633..1689
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg717_5_0001"
                     /evalue="7.60E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg717_5"
                     /protein_end="172"
                     /protein_start="153"
                     /score="18.6"
                     /tool="antismash"
                     /translation="ALIIYTSGTTGNCKGIVLSQ"
     CDS_motif       2251..2328
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg717_5_0002"
                     /evalue="1.00E-05"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg717_5"
                     /protein_end="385"
                     /protein_start="359"
                     /score="17.9"
                     /tool="antismash"
                     /translation="VGEILIRGDIVMKGYYNRKTFTKKNFF"
     CDS             3576..3860
                     /NRPS_PKS="Domain: PP-binding (17-86). E-value: 1.4e-07.
                     Score: 23.7. Matches aSDomain:
                     nrpspksdomains_ctg717_6_PP-binding.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg717_6"
                     /sec_met_domain="PP-binding (E-value: 3.3e-08, bitscore:
                     23.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNNVTLVELLLAKDIENKLIKIAADLSPMIEINDTKIIDVDFQDE
                     GYFDSFQLIEFIRRLEVSFGINLSADIILSNEFRTFRGIAGIIEKWQYD"
     aSDomain        3627..3833
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg717_6_PP-binding.1"
                     /evalue="1.40E-07"
                     /label="ctg717_6_PP-binding.1"
                     /locus_tag="ctg717_6"
                     /protein_end="86"
                     /protein_start="17"
                     /score="23.7"
                     /tool="antismash"
                     /translation="KLIKIAADLSPMIEINDTKIIDVDFQDEGYFDSFQLIEFIRRLEV
                     SFGINLSADIILSNEFRTFRGIAGI"
     aSModule        3627..3833
                     /domains="nrpspksdomains_ctg717_6_PP-binding.1"
                     /incomplete
                     /locus_tags="ctg717_6"
                     /tool="antismash"
                     /type="unknown"
     CDS             3906..4964
                     /locus_tag="ctg717_7"
                     /transl_table=11
                     /translation="MYRICNVKKDDYHGISSLLTQHYGKLPEFWKNRFKVWWDENPAFF
                     SFSDQVRGWALKKGDDIVGFLGNIPTKFQFCGEIVEACNGTSWFVASEHRNHGIKLFFH
                     LLRTPNSPVFITTPNETTLNIIKQLKIPLIPRGSDDGKKTVSGLPLVPMHQLSKDGWNI
                     READIEGLSREFLDKLSMGYHANKNQLSGIEQVTEAGVCFDDLWTRTKEIYQATNSRDA
                     DTINWLLANGNHKMTVFGYFKNKRLLGYIVVHENQKKGIIQCNDIWIYPEAGDIVDYFV
                     NFLFYYGKEKGFKLLLFPHFNEKLGFYLKNLGLFTVDLGDRVDYLYMPKSLMAVTHENS
                     YFCDLQGDYRIW"
     CDS             5001..6923
                     /gene_functions="biosynthetic (rule-based-clusters)
                     bacteriocin: TIGR03975"
                     /gene_functions="other (smcogs) SMCOG1277:Radical SAM
                     domain protein (Score: 119.6; E-value: 2.5e-36)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg717_8"
                     /sec_met_domain="TIGR03975 (E-value: 9.3e-155, bitscore:
                     505.9, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIFSKLESWNDSKARESLIAMFESYQTEEVILIVPPVAHLDRPS
                     LALHILQACAAKYAGTGVSVFYGNIAFGAWIGEEINNMFSYLSPSYLLSERLFAETAYG
                     NSLLGKNAEVAFNAMLRDYSKSEDNCVLSFSDLQTLALEAKHWVSDIAKLVVSKAPKVV
                     GCSTSFEQTAASVALLNAIKDLSPETITIIGGPNCAADMAEGVASLSASIDYIFSGDGE
                     IVFPTFLKQMKAGNLSKDRIIRSLPCLDMDLIPTPNYKEFYDQLSYLIEPLPRDLCIPF
                     ESSRGCWWGEKHQCTFCGLNSNNLKYRKKSPIRVVEELEELVTSYPAKILAAYDSIMPQ
                     SYYTEFLPLIKDRFNEFGIFYEQRSNINLKQMGQLKEAKVDIIQPGIEAISTSLLKRMN
                     KGIRTFQNIATMRYARIFDVAINWNLLYGFPGDQKEDYEETLRYLPLLHHLTPPILFSV
                     KIERFSLYFYKPSEFGIKNLRPLDSYSEVLPEHVDPRKIAYRFTCEYDSGSLENPEIID
                     KLKNEITLWRSKWLPKEEINDPRVISPPEKEETLPALKVTKVANDKYTLVDTRGIAENM
                     NTQTISHEQAYAALVTMSLKKLAISREVHQWAIANKVAIEIDGMHVALATANPDLLGVF
                     EAQNT"
     CDS             7154..8092
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     255; E-value: 1.5e-77)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg717_9"
                     /transl_table=11
                     /translation="MVKKTLGNNNELEVSTLCHGTDHFGSRVDYETSTAILDRYVAAGE
                     NFLDTSNFYAAWIEGFKGGESETLIGKWIKERKNRDQLIIATKVGVPYQDVPMGAKAKI
                     IEMEAEKSLKRLGIDTIDMYYTHLDDRSTPFEEQLEAMDKLVKAGKVRCIGACNILAWR
                     LEEARNVSLSNGFPLHSCVEQRYTYLRPKVNANFGGQVSTNSDLLDYCRSRNLQLIAYS
                     PLLHGAYMRNDRPLPPQYQHADSDVRMEALKAVAEELNATLNQIVIAWLMHQNIIPIIG
                     ASRVEQIEQNLGCLDINLTEAQMKTLNRAGI"
     CDS             8361..8918
                     /locus_tag="ctg717_10"
                     /transl_table=11
                     /translation="MKRITFFGSGTEIESIEGAIPDFENVVDVIKDYYHTLVYGGTNIG
                     YMNFFAEQCRTQGMEIESVIPVWFAEKYPNIVCNKSDTQILVDSLSKRKLRLMETDAII
                     CYPGGVGTFDEMFDVLARISLGELKQTPMFIYNFERFYSPLLLQMEYGIKTKYIKEAAL
                     ESVYTFEHSNQLRSVLKNLNDK"
     CDS             9018..11117
                     /gene_functions="other (smcogs) SMCOG1037:heavy metal
                     translocating P-type ATPase (Score: 406.5; E-value:
                     3.7e-123)"
                     /gene_kind="other"
                     /locus_tag="ctg717_11"
                     /transl_table=11
                     /translation="MLIQLLLVSTGGYWYLQRRKQRTIQHKLEPIARKEESTRRSATSF
                     STVHLLEDIKNALLVDGRQQLQMSLDPKLRESIEEEHRKKRRIFLFSSGAIGLALLSSV
                     YPSFFVLGSMGAIYLSRHLLQLLREDFKGGRYLTVPLIATVSMAGLIITGHLVLATAMG
                     LLGSFFAAILARVENKSNEQLTQVFTGHADNVWVLKDDVEIQISFHDIQPNDIIVVNSG
                     EVIPVDGVVHSGMGEVDQHILTGESQPIEKLVGAPVFASTLLLSGSLLIQVETSGELTV
                     AAKIGQILNQTQSYSKTLMVRGRELANRYVPVTLGISAFTFFVLGSQPALAVTWAALGA
                     TMEGLGPLSILSYLQILSQNAILVKDGRIFESLRQVDTVVFDKTGTLTLEQPTVGNIHV
                     IDGFDTISVLRYAAAAEYRQPHPTAKAIQAKAIEEQLDLPGLDDASYEVGYGIKAKIDK
                     KVIRVGSARFLEREGIELPETVRTIQLQAERDSYSLIYVAIGQQLAGILEMQPTLRPEA
                     KRVVRYLKQRGIELYIISGDHEAPTRNMAKILDIEHYVAETLPENKATLVKQLREEGRF
                     VCFIGDGINDAIALKSAQVSVSLKGASSAATDTAQIIFMDGTLSRLEQLFQLVDEFEGT
                     MEKNMAISMIPGIITISGVYLLRFCVATGMGLFYSGMIAGVGNALWPLVKHQNTTANQQ
                     GERHD"
ORIGIN
        1 agaattctgg ttgacagaat tatttgaaga ggcttgtggt ccgtctcgcc gaccacagga
       61 caagttggag caacgccata tggatattgc agctggagtg cagcgggtaa cagagatagc
      121 gatgcttcac actgtgaacc atttgcgtga aatatcaaat agtcctaacc tttgcatggc
      181 cggcggtgtc gccctgaact gtgtggcaaa tggcaaggtt caaagaggat gtgattttaa
      241 gaaagtattt gtccaacctg gggctaatga cgcagggact gccatcgggg cggcattgcg
      301 ttattattat cttcatgcag acaacttgcc caagaaaagg ccaggtggaa cttatacggg
      361 cactttttac agtgacaaag agattgagac ttgtctaaag gaaatgggtt tgccctatca
      421 aacccatcct gacatttttc aaaaaattgc tcgggaattg gctgatggtc gtattattgg
      481 ctggtttaac ggacgcatgg aatttggtcc tagggcattg ggaaatcgat ccatattgac
      541 ttcgccattt cccgcagaga tgaaggatat tattaatgac cgagtgaaac atagggaaga
      601 ttttaggccc ttcgcgccgg cagtgttact agaagacctt cagctttatt ttgagggtga
      661 tcaagaatcc ccctatatgc tgatgactta taaaacaagg aaagaacaag ttgattctat
      721 acctgctgtg acgcatgtgg atagaatggc gagagttcaa acggttacgg aagaaagtaa
      781 tccagtctta cgtcacttga ttgaggcgtt taagtccgtt actggtgtga gtgttttact
      841 gaatacgtcg ttcaatgtga tggggcagcc catagtagaa acgccacggc aagccgttga
      901 atgctttttg ggagtgcaga tggattttct cgtattcaac gcaaaattcg tcattgacgc
      961 aagtctggtt cctgatgagt ataaaaagtt aagaacgtga gtcatactca gtgcaatagt
     1021 ttgaggataa ggcgagtatg aaacatcttg tgtaatgcta tcttttatag gtgtggaact
     1081 cctcatacaa cctataatta agtttaagtc ataagaggcg agttttttta ccgtgtctct
     1141 cataacaaat ttacctgtaa tgtatgaatt aaaatgaatt tactttatag catgttaaca
     1201 aacgcaaagg ccaaggcagc tagtaaggcc tttctaaccg atattcaaaa taacgaacaa
     1261 tactcttatg agactcttta tgacttgact caatcaatac ggcatttgtt gagcgattat
     1321 aaggtggtta aaggagatcg ggtggctttc gtgacaagaa atgaagccat gttttatccg
     1381 ctgttttttg cttgttcagc ggtgggcgca gttcttgttc ccatcagccc agagaaccac
     1441 ccatcagaaa taaagtcaat gctgatggat gccaaaccga aacttacctt ctatggagaa
     1501 ggtatggagg atttgtcgat tttaggaaaa caacgaattg ctttgaagaa aagtaacctt
     1561 cctgcaatca ctggagagga aacattgaaa tgtcttcctt tgtccgatga agagtgctat
     1621 aaagatgatg atgctttaat tatttatacg tctggtacga cagggaattg taaagggatt
     1681 gtgctatctc aaaacaattt gtattctatg gcaaatgcat ttgcaacaat gtataagtat
     1741 caggagaatc aacgtttctt gtgcattctg cccttttatc atattaacgc aataatggtg
     1801 acgggtcttg cctgtgttct aagtcgagct catattgtat tgtcttctct tttcggacca
     1861 ttagttggta aatttttctg gaaaattgtc tctgataaca agatagatgt tcttagtctt
     1921 actccatcta ttatggcaat gttgctaaag ctttttccgt ctggagcaga tcatgatatc
     1981 tctcatgtga gtcatgcttt ggtgggcaca gctcccttaa gtaagacgtt atggaaacac
     2041 tttgaggata tttttggtat tccctgttac caggggtatg ggcttacgga aacgaccact
     2101 tgggcaacaa tgactcctat gaaagagccg agacattttg aaagtgttgg attgccaata
     2161 agttgttgcg aaataaaaat tatggagtac gattccgtag gagaggttgc ttatacacaa
     2221 catcaagaaa tggataaccg agataaaaaa gtgggggaaa ttcttattcg cggagacata
     2281 gtaatgaaag ggtactataa ccgaaaaacg ttcacgaaaa agaatttctt taaaggttgg
     2341 tttaagacag gagatatcgg ttattttggt aaagatgggc atttgtatat agttggcaga
     2401 atcaaaaata tcattaaacg caagggaata accctatttc ctgaagaggt caatgatgct
     2461 ttgagagaac atgagaatat tgtggactgt tgtgcttttg gtgtagaaga cgagctgctc
     2521 ggtgaaaaag taatattagc ttgcctagtt aaggacaagg aacaggaaga tgtgtcggaa
     2581 tttcgcagtt atcttcgcag tcggttatct tcgcataagc taccagatca atatgttatc
     2641 atgcgagagt ttcctagaac ttcaatgggt aagattaata tcaatgaact aaaaagtatt
     2701 gttggaggaa aacgagcttc cgaagtaatc aagttactta acatccctaa attcagaaga
     2761 gccaattgtg agaacgacag tgagattaat cgtttggttc aaaaatccat tctgtcaggt
     2821 gaaaaacttg gaatgattgc ttattggggg ggggggaaaa ggtcaaagct taacaagttc
     2881 gatattggag ccttggataa tatagaaatg atcaaagtgt ctataaatga gcttatggga
     2941 agaaagtcca ttgattttac gctaatactt acggatatcc atgtgaaagt aaatagggtg
     3001 ccaacggaaa tcatggaagc atattttgct gcaattcagt cagaagctga aagcagagaa
     3061 attaaaacga tccaattaag tcatatatgg gaaaaaagtg ggcttgattt tgatgctgtc
     3121 gtgaattctg tgaatcaacc tggatttaca gaaaagtgga aacgattcgg gcatcaagaa
     3181 ttatttatcc tacaagctga aaaaagatgc tctacgagtg aattagctat ggtccttgca
     3241 aaacaatatt ttgcaattgt tgaggctgag aatactgtaa ttgcaaggtt attcgcagat
     3301 catatatttt tcacttataa tgatttatca tataaaaagt ttttgcctaa attaccgacg
     3361 gttcattggt attcccatgt ggatgggaat accaagaaaa gtgataaacc ttggttcacc
     3421 aattaggaga taagcttttt ttctatttgg ggtgttatat gagaaaacac accttagggt
     3481 gaaatacgaa attggcacta tgttcataat ttttaaggat aaaatagaaa tacctatatt
     3541 cacccgaagg tgtcttttgt caaataacac cccatttgaa caatgtcaca ttagtggagt
     3601 tacttttggc caaagacata gaaaataaat tgataaaaat cgccgcagat ttgtctccta
     3661 tgatcgaaat taatgatact aagataatag atgtagattt tcaagatgag ggttattttg
     3721 attcatttca attgattgaa tttattcgca gactggaagt ttcttttggt atcaatttgt
     3781 ctgcggatat tatactgtct aatgagttcc gtactttcag agggattgct ggcattatcg
     3841 aaaaatggca atatgattga cttagccact cattgtggca tacataaata cttaggacat
     3901 gaaagatgta tcgtatttgc aatgtaaaaa aggacgatta tcatggaatc tcttcgttgc
     3961 tgactcaaca ttacggaaag ttgcctgaat tctggaaaaa taggttcaag gtgtggtggg
     4021 acgagaatcc agcctttttc tccttttctg atcaggtacg agggtgggca ctgaagaaag
     4081 gtgacgatat cgtaggtttt ttgggtaata ttcccacgaa attccaattt tgtggagaaa
     4141 tagtggaagc gtgtaatggg acatcatggt ttgtagcgtc tgagcataga aaccatggga
     4201 tcaaactgtt tttccattta ttgcgaactc ccaattcccc tgttttcatt accacgccaa
     4261 atgaaaccac tttaaacata atcaaacagt taaaaattcc gttgataccg aggggaagtg
     4321 atgatggaaa gaaaactgta tcgggtttgc ctctggtgcc gatgcaccaa ctttcaaagg
     4381 atggttggaa catccgtgaa gctgatatag aagggctctc acgagagttt ttggataagt
     4441 tgagtatggg ataccacgcc aataaaaacc aattgtctgg aattgaacaa gtcacagagg
     4501 cgggtgtttg cttcgatgat ctgtggacac gaactaaaga aatataccaa gccaccaact
     4561 cacgcgatgc agataccatc aactggcttc ttgctaatgg aaatcataag atgacagttt
     4621 ttggttattt caagaacaaa agactattag gctatattgt cgttcatgaa aaccagaaga
     4681 agggcatcat tcagtgcaat gatatttgga tatatcccga agctggcgat attgtagatt
     4741 attttgtgaa cttcttgttt tattatggca aagagaaggg ctttaagctc cttttgtttc
     4801 cccattttaa tgaaaaactc ggtttctatc ttaaaaactt gggcctattt acggtcgatt
     4861 tgggagaccg tgttgattat ctttatatgc ccaagtctct aatggctgtt acccacgaaa
     4921 actcctattt ttgtgattta cagggagact atcgtatttg gtaatgaata aaattaacaa
     4981 ggaaaaaccg taatattaga atgaacatat tttctaaatt agaatcttgg aatgactcta
     5041 aagccagaga aagtttgatt gctatgtttg agtcttacca aacagaagag gtcattctta
     5101 ttgtaccacc tgttgcacac cttgacagac cctctttggc tctccatatt ttacaggctt
     5161 gtgctgcaaa gtacgccggt accggagtga gtgtctttta tggtaatatc gcctttggtg
     5221 cttggattgg tgaagaaatc aataatatgt tttcttatct aagcccaagt tatttattgt
     5281 ctgaacgtct gtttgctgaa actgcatacg gaaattcact gctgggcaaa aatgctgaag
     5341 ttgctttcaa tgcaatgtta agagactatt ccaagagtga agacaattgt gtactgagtt
     5401 tttctgatct tcaaacattg gctctggaag ctaaacattg ggttagtgat atagcaaaac
     5461 tggtggtcag taaagctcca aaggttgtag gatgtagcac tagttttgaa cagacagctg
     5521 caagtgttgc gctcctcaat gctattaaag atttgtctcc tgagacaata actattatag
     5581 ggggaccaaa ctgtgcagca gatatggctg agggtgtggc atcactgagt gcttctattg
     5641 attacatttt ttccggtgac ggtgagattg tatttccaac tttccttaaa caaatgaagg
     5701 ctggtaattt atcaaaagat agaattatca gaagtttacc atgccttgat atggatttga
     5761 ttccaacacc aaactataaa gaattttatg atcagttatc gtatttaatt gaacctttac
     5821 ctcgtgatct ttgcatacca tttgagagca gtcgaggttg ctggtgggga gagaagcacc
     5881 aatgtacctt ctgcggtctt aatagtaata atttgaaata tagaaaaaaa tcaccaatcc
     5941 gtgttgtaga ggaattagaa gaactggtca cgtcttatcc cgcgaaaata ctagcggcgt
     6001 atgatagtat catgcctcaa tcttattaca cggaattttt gcctctcata aaagataggt
     6061 ttaatgagtt tgggatattt tatgaacaga ggtctaacat caatctaaag cagatggggc
     6121 aactcaaaga ggcaaaggta gatataatac aaccgggtat agaagctatc tcaacatctt
     6181 tattaaagcg tatgaataaa ggtattagaa cctttcagaa tatagccacc atgcgttatg
     6241 cacgcatatt tgatgttgcg atcaattgga atctattgta cggttttcca ggagatcaga
     6301 aagaggacta tgaagaaaca ttacgttatc ttcctctgtt gcatcacctt acaccgccta
     6361 tattatttag tgttaaaatt gaacgattca gcctgtattt ttacaaacct tctgaatttg
     6421 gcatcaaaaa tctaaggcca ttagattctt attctgaggt tttaccagaa catgtggacc
     6481 caagaaaaat agcttatcgc tttacctgtg agtatgatag tggttctctg gaaaatccgg
     6541 agattattga taagcttaaa aatgagataa cgttatggcg atctaaatgg ttaccaaagg
     6601 aagagattaa tgatcccaga gttatttctc ctcctgaaaa ggaggaaact cttccagcac
     6661 taaaggtaac caaagtggca aatgacaaat atactcttgt ggacactcgt ggtattgcag
     6721 aaaatatgaa tacgcagact atcagtcacg aacaggccta cgcagcatta gttaccatgt
     6781 cgttaaaaaa attagcgatt tctagggaag tgcatcagtg ggctattgct aataaagttg
     6841 ccattgaaat agatggtatg catgtggcat tggcaacagc taatcctgat ttattgggcg
     6901 tttttgaggc gcaaaatact taaaacctga gttacgcaca atttaaaatg aacgatgcgg
     6961 gaacaagttt gcaaccagtt cctgaacgtt ttttccggct tgtcttaaaa tgttgcgagc
     7021 gggtttacaa aacccgccca gcaaggagat actggaactc aaatatctct atataccaaa
     7081 aaattctatt tttactaaaa tttcgtgaag gatgcccaaa tgttaaattt gcttaggata
     7141 aaaaggagaa gcaatggtaa agaagacgct tggaaacaac aatgaacttg aagtgagtac
     7201 cctgtgtcac ggaacggatc acttcggcag ccgggtcgat tatgaaacct ctacggccat
     7261 actcgatcgg tatgtcgcag cgggggaaaa ttttctggac acctcgaatt tttatgcagc
     7321 gtggattgaa ggatttaaag gcggagaatc agaaacgctg atcggcaagt ggataaaaga
     7381 gcgaaaaaac cgcgatcagc ttattattgc tacgaaagtg ggtgttccct atcaggatgt
     7441 gccgatgggc gcaaaagcaa agatcattga aatggaagcc gaaaaaagcc taaaacggct
     7501 gggtattgat acgatcgata tgtattatac ccatttggat gaccggtcta cgccttttga
     7561 agagcaactc gaagcgatgg ataagctggt gaaagccggt aaggtcagat gcatcggtgc
     7621 gtgcaatatt ctggcatggc gtctggaaga agcccggaat gtcagtttga gcaatggttt
     7681 tccgcttcat tcctgcgtag aacagcgata tacctattta agaccgaagg taaatgccaa
     7741 tttcggtggc caagtctcca ctaatagcga tctgcttgat tactgccgaa gccgaaactt
     7801 gcagttgatt gcctactcac cgctgcttca cggcgcgtat atgcggaatg atcgtccctt
     7861 gccgccccaa taccagcatg ctgattcgga tgtccgaatg gaagcactta aagcagttgc
     7921 tgaagagcta aatgccacac tcaatcagat tgttatcgct tggctgatgc accaaaatat
     7981 catacctatc attggcgcaa gtcgcgttga gcaaattgag cagaatttgg gttgtctgga
     8041 cataaatctg actgaagcgc aaatgaagac gttaaatcgg gcaggcattt aacggctcta
     8101 tctaatttcc ttatatggca ttggcaaaat agctagctga ccctgattta ttgagcgttt
     8161 ttgaggcgca aaataaatac ttaaaatttt atattcaaac gtttatttta cttataacgt
     8221 aaatgcccgt taggagatga aaagtgtatt gtatttgcaa tgtaaaaacg gacgattatc
     8281 ctgggatata aacaaacccc aagtatttaa atacaatatt atactttttg tgctttttgt
     8341 gaaatacaaa ggaaattgat atgaaaagaa taactttttt tggttctgga accgaaattg
     8401 aatctataga gggagctatt cctgattttg agaatgtcgt tgatgtaatt aaggattact
     8461 accacacgct agtctatgga ggaaccaata ttggatacat gaattttttt gccgagcaat
     8521 gcagaacaca gggcatggaa attgaatctg tgattccagt ttggttcgct gaaaagtatc
     8581 caaatatagt gtgcaacaaa tctgatacac aaatattggt agattccttg tcaaagcgaa
     8641 aactacgact gatggaaaca gatgcgatta tttgttaccc cggaggtgtt ggtacttttg
     8701 atgaaatgtt tgatgtgctt gcaaggatat cactcggtga attaaaacaa acgcccatgt
     8761 ttatctataa ttttgaacga ttctactctc ctcttctttt gcaaatggaa tatggtatta
     8821 agacaaaata tataaaggaa gcagcgctgg aatccgtgta tacttttgaa catagcaacc
     8881 agttgcgttc ggttctgaag aatctaaacg ataaatgaaa attggagctt ggaacttgat
     8941 ttatttgact tcataaagtc atcaaaggat ggttgcttac gattcatgaa aataattact
     9001 attgaggagc aagaatcatg ctgatccaac tcttgttggt gagtactgga ggatattggt
     9061 acttacagcg acggaagcaa agaacaatac aacataaatt agaacccatt gctaggaagg
     9121 aagagtcaac cagaagatca gcaacttcct ttagtactgt ccatttactg gaggatatca
     9181 agaatgcgct gttggtagat ggtcgccagc aattacagat gagtcttgat cctaaattac
     9241 gtgaatctat tgaagaagaa catcgaaaga aaaggcgaat ttttctattt tcgtctggtg
     9301 ccataggact ggctctcttg agtagtgttt acccatcctt ttttgtcctt ggtagcatgg
     9361 gggctattta tctgtcacgc catctccttc aacttctcag ggaggatttc aagggaggac
     9421 gttacttgac ggttcctctg attgccaccg tctcaatggc tggcttgatt atcaccggac
     9481 acttggtttt ggcgactgcc atgggactcc ttggtagttt ttttgcagca atcttagctc
     9541 gggtggaaaa caagtcaaat gaacagttaa cccaggtatt tactggacat gctgacaatg
     9601 tttgggtact gaaggatgat gtcgagatcc aaatcagttt ccatgacatc caacccaatg
     9661 atatcatagt tgtcaactct ggagaagtca ttcctgtgga tggagtagtt cattctggaa
     9721 tgggtgaggt tgaccagcac atcctgacgg gtgaaagtca gccaatcgaa aaattagttg
     9781 gtgctccagt gttcgcttca actctgctgc tgtctggctc ccttctcatt caagtggaaa
     9841 ctagcggtga actcacggta gccgccaaga ttggccagat acttaaccag actcaaagtt
     9901 acagtaaaac tttgatggtt cgtgggcgtg aactagccaa tcgctatgtg ccagtcactt
     9961 tgggaatcag tgcttttacc ttttttgtgt tgggatccca gcctgcgtta gctgtcacat
    10021 gggctgcact aggggcaacc atggaaggct tgggaccgct tagtatattg agttatctgc
    10081 aaatcctatc acaaaatgct atcctagtta aggatgggcg aatatttgaa tccttgcggc
    10141 aagtggatac cgtcgtcttt gataagactg gtaccttaac cttggaacag ccaactgtag
    10201 gcaatattca tgtgatagat ggtttcgata caataagtgt gttgcgttat gctgctgctg
    10261 ccgaatatcg tcagccacat cccactgcta aagccataca agccaaagcg atagaagaac
    10321 aactagattt acctggacta gacgatgcca gttatgaagt tggttatggc attaaagcaa
    10381 agattgataa aaaagtcata cgggttggca gtgcccgttt cctagaacgc gaaggtattg
    10441 agttgcctga aaccgttcgt accatccaac tgcaggcgga acgggacagt tattccctca
    10501 tctatgtcgc gataggtcag cagcttgcag gtatcctgga aatgcagcct actcttcgtc
    10561 cagaagccaa acgtgttgtt cgctacctga aacagcgtgg tatagaactg tatattatct
    10621 caggggacca tgaagccccg actcgaaata tggctaaaat actggatatc gagcattacg
    10681 ttgccgaaac tctgccggaa aataaggcta cgttagtgaa gcaattacgt gaagaaggcc
    10741 gttttgtttg ttttattggt gatggcatta atgatgccat tgccctgaaa tcggcgcaag
    10801 tatctgtttc ccttaaaggt gcttcaagtg ccgctactga taccgcacag atcattttta
    10861 tggatggaac cttgagtcga ttggagcaac tcttccagtt agtggatgag tttgaaggca
    10921 ctatggagaa aaacatggcc attagtatga tacctggcat aattactatc agcggagttt
    10981 atttactgcg tttttgtgtt gctacaggaa tggggctttt ttattctggg atgattgctg
    11041 gagtggggaa tgcgctttgg cctttagtta aacatcaaaa cacaacagca aatcaacaag
    11101 gtgaaaggca tgactaataa tataatagcg ggctccatcc ccaatggcat tcgttcctcc
    11161 tcaaccgggt aaggtgcgtt agccctccga gctcacgcac tgtaagatac gcgaaacttt
    11221 gttcttggag caggcagttt cttctgcatc actcaggcat ttgcagaaga caaatggatg
    11281 ctaactttag aaaacggttc atcgcatgtt caacaatgga gtgtgcggaa tatgcatgag
    11341 gtagatgtgt aattatccgg gcgaaggctc taaatgacct gacaaacctc accaattaaa
    11401 gtagggcacc ctacatgaga attcaaattg aattcgattt acatcaaatg gataaaactg
    11461 tcgtatacaa tttgacggat tgtagcccgt aggttggact aagcttgcga agtccaacaa
    11521 tcatgttaaa aactcaattt atttttgggt tttgttggac ttccttcgtc agtccaacct
    11581 actacgagct actcacggga acctttgcga tagtcctcgt tgagtttggc catttggtta
    11641 atttgattga atttatcgct aagtggccac tccaaaggcc tacgcgaaat gattttgtaa
    11701 caaacaatta aacttcattc aatcgggaaa ggctatagag ggtgcgaaac gagaatcaag
    11761 tttaatgaaa ttaatgttca aagcaactag tgcagtaaag cggaaatgat cataccaccc
    11821 agccaactaa agccaacagc taaagcagtt gtctaaaagc taaagtcaca taaaggtgac
    11881 tacatccaca caattattat tgttagcatc atttttgtca aaa
//
