3300014916_2 - 6 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

c00021_3300014.. (original name was: 3300014916.a:Ga0169762_100205)

Region	Type	From	To	Most similar known cluster		Similarity
Region 21.1	sactipeptide	712	20,852

c00029_3300014.. (original name was: 3300014916.a:Ga0169762_100070)

Region	Type	From	To	Most similar known cluster		Similarity
Region 29.1	NRPS	17,417	60,710

c00035_3300014.. (original name was: 3300014916.a:Ga0169762_100250)

Region	Type	From	To	Most similar known cluster		Similarity
Region 35.1	lanthipeptide	13,799	36,429

c00062_3300014.. (original name was: 3300014916.a:Ga0169762_100133)

Region	Type	From	To	Most similar known cluster		Similarity
Region 62.1	lanthipeptide	38,452	61,397

c00066_3300014.. (original name was: 3300014916.a:Ga0169762_100081)

Region	Type	From	To	Most similar known cluster		Similarity
Region 66.1	NRPS	1	54,611

c00086_3300014.. (original name was: 3300014916.a:Ga0169762_100206)

Region	Type	From	To	Most similar known cluster		Similarity
Region 86.1	NRPS	10,823	50,504

Region	Type	From	To	Similarity
Region 21.1	sactipeptide	712	20,852
Region 29.1	NRPS	17,417	60,710
Region 35.1	lanthipeptide	13,799	36,429
Region 62.1	lanthipeptide	38,452	61,397
Region 66.1	NRPS	1	54,611
Region 86.1	NRPS	10,823	50,504

No secondary metabolite regions were found in these records:: c00001_3300014.. (original name was: 3300014916.a:Ga0169762_101523); c00002_3300014.. (original name was: 3300014916.a:Ga0169762_101407); c00003_3300014.. (original name was: 3300014916.a:Ga0169762_101338); c00004_3300014.. (original name was: 3300014916.a:Ga0169762_101250); c00005_3300014.. (original name was: 3300014916.a:Ga0169762_101231); c00006_3300014.. (original name was: 3300014916.a:Ga0169762_101199); c00007_3300014.. (original name was: 3300014916.a:Ga0169762_101179); c00008_3300014.. (original name was: 3300014916.a:Ga0169762_101484); c00009_3300014.. (original name was: 3300014916.a:Ga0169762_101086); c00010_3300014.. (original name was: 3300014916.a:Ga0169762_101007); c00011_3300014.. (original name was: 3300014916.a:Ga0169762_101394); c00012_3300014.. (original name was: 3300014916.a:Ga0169762_100996); c00013_3300014.. (original name was: 3300014916.a:Ga0169762_100958); c00014_3300014.. (original name was: 3300014916.a:Ga0169762_100875); c00015_3300014.. (original name was: 3300014916.a:Ga0169762_100368); c00016_3300014.. (original name was: 3300014916.a:Ga0169762_100562); c00017_3300014.. (original name was: 3300014916.a:Ga0169762_100030); c00018_3300014.. (original name was: 3300014916.a:Ga0169762_100257); c00019_3300014.. (original name was: 3300014916.a:Ga0169762_100210); c00020_3300014.. (original name was: 3300014916.a:Ga0169762_100252); c00022_3300014.. (original name was: 3300014916.a:Ga0169762_100108); c00023_3300014.. (original name was: 3300014916.a:Ga0169762_100302); c00024_3300014.. (original name was: 3300014916.a:Ga0169762_100235); c00025_3300014.. (original name was: 3300014916.a:Ga0169762_100186); c00026_3300014.. (original name was: 3300014916.a:Ga0169762_100199); c00027_3300014.. (original name was: 3300014916.a:Ga0169762_100152); c00028_3300014.. (original name was: 3300014916.a:Ga0169762_100258); c00030_3300014.. (original name was: 3300014916.a:Ga0169762_101642); c00031_3300014.. (original name was: 3300014916.a:Ga0169762_101244); c00032_3300014.. (original name was: 3300014916.a:Ga0169762_100846); c00033_3300014.. (original name was: 3300014916.a:Ga0169762_100239); c00034_3300014.. (original name was: 3300014916.a:Ga0169762_101046); c00036_3300014.. (original name was: 3300014916.a:Ga0169762_100051); c00037_3300014.. (original name was: 3300014916.a:Ga0169762_100148); c00038_3300014.. (original name was: 3300014916.a:Ga0169762_100044); c00039_3300014.. (original name was: 3300014916.a:Ga0169762_100123); c00040_3300014.. (original name was: 3300014916.a:Ga0169762_100817); c00041_3300014.. (original name was: 3300014916.a:Ga0169762_100220); c00042_3300014.. (original name was: 3300014916.a:Ga0169762_100032); c00043_3300014.. (original name was: 3300014916.a:Ga0169762_100862); c00044_3300014.. (original name was: 3300014916.a:Ga0169762_100265); c00045_3300014.. (original name was: 3300014916.a:Ga0169762_100193); c00046_3300014.. (original name was: 3300014916.a:Ga0169762_100188); c00047_3300014.. (original name was: 3300014916.a:Ga0169762_100387); c00048_3300014.. (original name was: 3300014916.a:Ga0169762_100099); c00049_3300014.. (original name was: 3300014916.a:Ga0169762_100788); c00050_3300014.. (original name was: 3300014916.a:Ga0169762_100159); c00051_3300014.. (original name was: 3300014916.a:Ga0169762_100251); c00052_3300014.. (original name was: 3300014916.a:Ga0169762_100450); c00053_3300014.. (original name was: 3300014916.a:Ga0169762_100121); c00054_3300014.. (original name was: 3300014916.a:Ga0169762_100219); c00055_3300014.. (original name was: 3300014916.a:Ga0169762_100913); c00056_3300014.. (original name was: 3300014916.a:Ga0169762_100515); c00057_3300014.. (original name was: 3300014916.a:Ga0169762_100316); c00058_3300014.. (original name was: 3300014916.a:Ga0169762_100031); c00059_3300014.. (original name was: 3300014916.a:Ga0169762_100054); c00060_3300014.. (original name was: 3300014916.a:Ga0169762_100224); c00061_3300014.. (original name was: 3300014916.a:Ga0169762_100423); c00063_3300014.. (original name was: 3300014916.a:Ga0169762_100046); c00064_3300014.. (original name was: 3300014916.a:Ga0169762_100725); c00065_3300014.. (original name was: 3300014916.a:Ga0169762_100095); c00067_3300014.. (original name was: 3300014916.a:Ga0169762_100280); c00068_3300014.. (original name was: 3300014916.a:Ga0169762_100178); c00069_3300014.. (original name was: 3300014916.a:Ga0169762_100377); c00070_3300014.. (original name was: 3300014916.a:Ga0169762_101080); c00071_3300014.. (original name was: 3300014916.a:Ga0169762_100284); c00072_3300014.. (original name was: 3300014916.a:Ga0169762_100309); c00073_3300014.. (original name was: 3300014916.a:Ga0169762_100709); c00074_3300014.. (original name was: 3300014916.a:Ga0169762_100112); c00075_3300014.. (original name was: 3300014916.a:Ga0169762_100311); c00076_3300014.. (original name was: 3300014916.a:Ga0169762_100132); c00077_3300014.. (original name was: 3300014916.a:Ga0169762_100331); c00078_3300014.. (original name was: 3300014916.a:Ga0169762_100142); c00079_3300014.. (original name was: 3300014916.a:Ga0169762_100341); c00080_3300014.. (original name was: 3300014916.a:Ga0169762_100544); c00081_3300014.. (original name was: 3300014916.a:Ga0169762_100238); c00082_3300014.. (original name was: 3300014916.a:Ga0169762_100835); c00083_3300014.. (original name was: 3300014916.a:Ga0169762_100352); c00084_3300014.. (original name was: 3300014916.a:Ga0169762_100367); c00085_3300014.. (original name was: 3300014916.a:Ga0169762_100561); c00087_3300014.. (original name was: 3300014916.a:Ga0169762_100405); c00088_3300014.. (original name was: 3300014916.a:Ga0169762_100453); c00089_3300014.. (original name was: 3300014916.a:Ga0169762_100488); c00090_3300014.. (original name was: 3300014916.a:Ga0169762_100494); c00091_3300014.. (original name was: 3300014916.a:Ga0169762_100097); c00092_3300014.. (original name was: 3300014916.a:Ga0169762_100495); c00093_3300014.. (original name was: 3300014916.a:Ga0169762_100490); c00094_3300014.. (original name was: 3300014916.a:Ga0169762_100689); c00095_3300014.. (original name was: 3300014916.a:Ga0169762_100125); c00096_3300014.. (original name was: 3300014916.a:Ga0169762_100523); c00097_3300014.. (original name was: 3300014916.a:Ga0169762_100334); c00098_3300014.. (original name was: 3300014916.a:Ga0169762_100533); c00099_3300014.. (original name was: 3300014916.a:Ga0169762_100824); c00100_3300014.. (original name was: 3300014916.a:Ga0169762_100140); c00101_3300014.. (original name was: 3300014916.a:Ga0169762_100538); c00102_3300014.. (original name was: 3300014916.a:Ga0169762_100572); c00103_3300014.. (original name was: 3300014916.a:Ga0169762_100271); c00104_3300014.. (original name was: 3300014916.a:Ga0169762_100669); c00105_3300014.. (original name was: 3300014916.a:Ga0169762_100605); c00106_3300014.. (original name was: 3300014916.a:Ga0169762_100202); c00107_3300014.. (original name was: 3300014916.a:Ga0169762_100799); c00108_3300014.. (original name was: 3300014916.a:Ga0169762_101417); c00109_3300014.. (original name was: 3300014916.a:Ga0169762_100820); c00110_3300014.. (original name was: 3300014916.a:Ga0169762_100621); c00111_3300014.. (original name was: 3300014916.a:Ga0169762_100815); c00112_3300014.. (original name was: 3300014916.a:Ga0169762_100328); c00113_3300014.. (original name was: 3300014916.a:Ga0169762_100726); c00114_3300014.. (original name was: 3300014916.a:Ga0169762_100549); c00115_3300014.. (original name was: 3300014916.a:Ga0169762_100350); c00116_3300014.. (original name was: 3300014916.a:Ga0169762_100748); c00117_3300014.. (original name was: 3300014916.a:Ga0169762_100856)

Compact view

c00021_3300014.. - Region 1 - sactipeptide

Download region GenBank file

Location: 712 - 20,852 nt. (total: 20,141 nt) Show pHMM detection rules used

sactipeptide: (subtilosin or thuricin or TIGR04404 or TIGR03973)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Sactipeptides

Sactipeptide predictions

Sactipeptides - No core peptides found.

Sactipeptides

Core peptide predictions

No core peptides found.

c00029_3300014.. - Region 1 - NRPS

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Location: 17,417 - 60,710 nt. (total: 43,294 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

c00035_3300014.. - Region 1 - lanthipeptide

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Location: 13,799 - 36,429 nt. (total: 22,631 nt) Show pHMM detection rules used

lanthipeptide: ((LANC_like and (Lant_dehydr_N or Lant_dehydr_C) or cds(LANC_like and (Pkinase or DUF4135))) and not (YcaO or TIGR03882))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Lanthipeptides

Lanthipeptide predictions

Lanthipeptide(s) for ctg35_22 - Putative Class II

allorf_34787_34972 leader / core peptide: MSLNFSTYAYITKSPVRYSDAAVFSA - AAPDYHHPELFPVLLLFHDhbRELYPHMDhbEVDhbCFQDhbL

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lanthipeptides

Core peptide predictions

allorf_34787_34972 - Class II

Cleavage pHMM score: -6.80

RODEO score: 0

Monoisotopic mass: 4093.1 Da

Molecular weight: 4095.7 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 4113.7 Da N = 1; 4131.7 Da N = 2; 4149.7 Da N = 3

c00062_3300014.. - Region 1 - lanthipeptide

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Location: 38,452 - 61,397 nt. (total: 22,946 nt) Show pHMM detection rules used

lanthipeptide: ((LANC_like and (Lant_dehydr_N or Lant_dehydr_C) or cds(LANC_like and (Pkinase or DUF4135))) and not (YcaO or TIGR03882))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

Lanthipeptides

Lanthipeptide predictions

Lanthipeptide(s) for ctg62_48 - Putative Class II

ctg62_49 leader / core peptide: MFAEFEKEEMLNDEDLYINAM - NNDDhaADhaDhaYADhaNVDhaDDhaCCC

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lanthipeptides

Core peptide predictions

ctg62_49 - Class II

Cleavage pHMM score: -4.00

RODEO score: 0

Monoisotopic mass: 1717.6 Da

Molecular weight: 1718.7 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 1736.8 Da N = 1; 1754.8 Da N = 2; 1772.8 Da N = 3

c00066_3300014.. - Region 1 - NRPS

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Location: 1 - 54,611 nt. (total: 54,611 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 54611:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (cys - cys) + (cys)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg66_21

Search NORINE for peptide: strict or relaxed

AMP-binding (537..917): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLFNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

ctg66_22

Search NORINE for peptide: strict or relaxed

AMP-binding (20..397): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLFNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

ctg66_25

Search NORINE for peptide: strict or relaxed

AMP-binding (553..948): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNMSMIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

AMP-binding (1974..2374): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNMSLiWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 90% (moderate)

ctg66_26

Search NORINE for peptide: strict or relaxed

AMP-binding (25..431): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: PLPAQGVLsK
Nearest Stachelhaus code:: sal
Stachelhaus code match:: 90% (moderate)

c00086_3300014.. - Region 1 - NRPS

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Location: 10,823 - 50,504 nt. (total: 39,682 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 10822 - 50504:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg86_30

Search NORINE for peptide: strict or relaxed

AMP-binding (22..421): X

NRPSPredictor2: gly, ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: gly, ala
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVLtdgGIsK
Nearest Stachelhaus code:: aeo
Stachelhaus code match:: 60% (weak)

AMP-binding (1035..1423): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAmfsGAIfK
Nearest Stachelhaus code:: bht
Stachelhaus code match:: 60% (weak)

AMP-binding (2029..2420): X

NRPSPredictor2: phe, trp, phg, tyr, bht

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAiTTGgVsK
Nearest Stachelhaus code:: tyr
Stachelhaus code match:: 70% (weak)