LOCUS       c00007_3300014..       10848 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300014970.a:Ga0169826_100630.
ACCESSION   c00007_3300014..
VERSION     c00007_3300014..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 12:15:18
            Original ID  :: 3300014970.a:Ga0169826_100630
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10848
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10848
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[8591:10781](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      8592..10781
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..10848
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10848
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             831..2129
                     /locus_tag="ctg7_1"
                     /transl_table=11
                     /translation="METKLARISQLSKENPDMVFTSLGHLINKEMLENCHVQMDGTKAV
                     GIDGVTKEEYGRNLEENLEALIESLKKKSYKPKPARLVEIPKDNGKMRPLSIYCYEDKL
                     VQEALRRILEAVFEPMFYDEMMGFRPNRGCHKAIRKLNIMLERKPTNYVLDADIKGFFQ
                     HLDHEWIVRFIESRIKDPNIIRLVRRMLKAGIMNNYEFEATEEGSGQGSVCSPIISCIY
                     MHYVLIWWFREVVTPMLKGYAGLVVYADDFVVTFQYKSDAVWFYEHLKHRMGHFGLSLE
                     EEKSRLIEFGRYAKERCSKSGTKPGTFTFLGFTHYCSKSKNGRFRVKRKTSKKKFAKKC
                     REINQLMGHMKTWKLKEITAKLNQILTGYYHYYGITDNTERITAFRYHVMKSLFYCLNR
                     RSQKKSYNWVEFLNMIDNSYPLVRPRIYVSVYN"
     CDS             2486..3046
                     /locus_tag="ctg7_2"
                     /transl_table=11
                     /translation="VDIYQIIITHNRSWTIREIIAFAVVFLMAVFLAAVLLRLHKIVII
                     QAVCGLLLLTFLSIVFGSTVFTRTPGIRQYQPEVFWSWKEILGIGTCGRLGSTTGDGLL
                     QENLLNILLLFPAGILLPGVTGRKLKWWMGLLVGIAVSSAIEISQLLLCRGLFEFDDII
                     HNSLGCMLGSLLGNRMLRLVHGK"
     CDS             complement(2970..3176)
                     /locus_tag="ctg7_3"
                     /transl_table=11
                     /translation="MKAAPADSRDGFQNASQKLLSFERDLPEIAIQDDLSVFHLVLPFT
                     FHVPTLTSYSPTKTPAYIPNYYE"
     CDS             3436..4272
                     /locus_tag="ctg7_4"
                     /transl_table=11
                     /translation="MLYIGNHTSSSRGYLAMGKQMLANGGNTFAFFTRNPRGGKAKDID
                     PQDVQAFGQLAEENHFGKLVAHAPYTMNCCTAKENLRDFAREIMADDLRRLEMTPGNYY
                     NFHPGSHVGQGAEVGISKIAEILNEVLTKDQSTIVLLETMSGKGTEVGRNFEELRQIID
                     KVELKDKLGVCLDTCHVWDGGYDIVNDLDSVFEEFDRIIGLDRLKAIHLNDSMNPLGSH
                     KDRHARIGEGEIGLETLVRVINHPATEGIPFILETPNDDEGWTHEIALLRNEYKQK"
     CDS             4426..4836
                     /locus_tag="ctg7_5"
                     /transl_table=11
                     /translation="MQQRSEMQQRQGYQAVEKLRETLDEKYLWEVILLYAGESFKTYTG
                     LPFTYEVRKGRNGDYTRELWIDRRENSKSLALSSVLLALRNIKKVGAVVDRPKALGDIR
                     GVSYIYGMFYRFGLIDVPDTARQKMKFTGYIF"
     CDS             4847..6700
                     /locus_tag="ctg7_6"
                     /transl_table=11
                     /translation="MNKKRNVDSGRKSARPDYIQKTISQKSSGKRSGKVFFPKTLIKTG
                     GIIIFVLLLGFAGNKFFLSVSKTDSGKVKAVSASGADEEKGGWIIGKTKETKDVVEMKK
                     TKEINFQPHCVDSTKPENLISYTNIEVDGNVLENIGDYKADGDISFNIGQDYTDVDGIV
                     TFRGNSFRDAPSHGYADMTDFRLDKLWSADTGSLSSGSAVWTGSGWTGQPLMMKWPKEV
                     KAHMNMTEKAKADDELVEVIYACMDGYVYFLDLRTGEKTRDPLYLGYTFKGAGALDPRG
                     YPIMYVGAGYNSNEGTAKVFVVNLLDCSVMYTFGDNDEFSLRGSLSFFDGSALVDAETD
                     TLIYPGENGILYLIRLNTKYDLNSGTLSIDPGRTVKWRYYGTRSSTESFWLGMEDSAAI
                     YKGYIFMTDNGGNLMCLDLNTLQLVWVQDTLDDSNSTPVLEIEKGHLYLYVSTSFRLGW
                     RSYDTATVPVWKIDAETGEIVWHTDYECTTDDGVSGGVQSTIACGKNSLADYIYVTVAK
                     TSDNASGVLACLRKSDGSKAWEDSSSYAWSSPVCVYNKDGSGKVLYCNSTGDIRLLDGK
                     TGKQEDVLSVSEGVIEASPAVYDNYAVVGTRDCKIWGIRLQ"
     CDS             6833..8578
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 265.4; E-value: 1.4e-80)"
                     /gene_kind="transport"
                     /locus_tag="ctg7_7"
                     /transl_table=11
                     /translation="MEERNNRLLNAKLNKYIVPGIMMSLALQLGNIVDTIFVSNLIGVE
                     AMSAVTLSLPVETIVQLTGYCLGIGGSIAVGNMLGKRDKEGASKLFSATFIVTLVVGII
                     FSICALPAAEPVARLLVSGDGVLTGYTRDYIRVSMLGAPVIGIGLMMVNYLGVENHPEL
                     ASAYLIAANVINLVLDYIFLRYTPLGITGASLSTVLGFLFAMGIFVLYIRSDKRNLHLI
                     LLKPGELGITKEAIITGVPMLIFMAANFVKALGLNTIIMNQLGEEGMAVFTVCDNVLLI
                     VEMLTGGIIGVIPNVAGILFGEKDYVGIRVLCKKMLKYSYILLAVIFVLIMLFTEEITV
                     MFGSGGGELGSHMVQALRIFALCVAPYLWNKFIISYYESIEETAIASFATFLENAVVVL
                     PATLVGILVWKQIDGIGIDGIAAGFVATEIITAVAACIFRKIRHKNTSFYIVPDKNPGI
                     NLDFSIKSTMEEAQTVHKRIIEFCQEQGASKSKANLAAVCAEEMTVNIIRFGGKTSNWI
                     DINLCLEDDLCRLRIRDNGVNFNPLEYQYDSEDFDIHGIELVKKVSKSMDYIRAIDMNN
                     TIISF"
     CDS             8592..10781
                     /NRPS_PKS="Domain: AMP-binding (20-419). E-value: 7.5e-105.
                     Score: 342.5. Matches aSDomain:
                     nrpspksdomains_ctg7_8_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (521-585). E-value: 2.2e-12.
                     Score: 39.1. Matches aSDomain:
                     nrpspksdomains_ctg7_8_PP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     308.8; E-value: 9.1e-94)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_8"
                     /sec_met_domain="Condensation (E-value: 1.5e-22, bitscore:
                     69.1, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-108, bitscore:
                     352.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.5e-13, bitscore:
                     39.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNINERNNFAFEFRPVTELFEEQVKLHPEKCAVVSGKESFTYAQ
                     LNERANRIANALVEKGVRRETIVGVVLERCCDFYAVRQGILKAGGAFAVATSDYPDDRI
                     RYIFEDSGAPFIITTKEIAEERRELFAKLPCTVLLIEELLENENIENPQVKIGEHDLCY
                     CIYTSGSTGKPKGVLIEHINLSNFVNPDPKNAETYGYVSRGSVSLSMAAMTFDVSVLEE
                     FLPLTNGMTAVIASDEEILNPLMLGELIVRNKVDIMTTTPTYLSNMIDLPQLEKAVSQI
                     KVFDVGAEAFPPALYDKIRRVNPDAYIMNGYGPTETTISCTMKVITDSRNITIGTPNGN
                     VKVYIVDKENKILPDGETGELVIAGLGVGRGYMNLPDKTEAVFIDLNGERAYKTGDLAR
                     ISPEGEIEFFGRIDNQIKLRGLRIELGEIEEVINSYEGIITSITLPVDNKFLCCYFMAD
                     RQINTEELSAYASESLAHYMVPEVFVQLEKMPVTQNGKIDKKALPKPVAQPKNLKEPQT
                     PMQKKIFEIVADVVENDFFGTDTSFYRAGLSSISAMKLCILISEEFGVTVKTSDIHENN
                     TVEKLEKYVMLAPKIRTYEKREVYPLTGSQKGIFAECMKNPESTVYNIPFLFELESSVD
                     VQKLSDAISQMIAAHPYLLTKVYLSDSGEMVQKPCEEAFVPEVVRTTNEQFEKMKDELV
                     RPFKLEKGRLFRAGIYVTEDRKYLFTDFHHILERV"
     aSDomain        8652..9848
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg7_8_AMP-binding.1"
                     /evalue="7.50E-105"
                     /label="ctg7_8_AMP-binding.1"
                     /locus_tag="ctg7_8"
                     /protein_end="419"
                     /protein_start="20"
                     /score="342.5"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FEEQVKLHPEKCAVVSGKESFTYAQLNERANRIANALVEKGVRRE
                     TIVGVVLERCCDFYAVRQGILKAGGAFAVATSDYPDDRIRYIFEDSGAPFIITTKEIAE
                     ERRELFAKLPCTVLLIEELLENENIENPQVKIGEHDLCYCIYTSGSTGKPKGVLIEHIN
                     LSNFVNPDPKNAETYGYVSRGSVSLSMAAMTFDVSVLEEFLPLTNGMTAVIASDEEILN
                     PLMLGELIVRNKVDIMTTTPTYLSNMIDLPQLEKAVSQIKVFDVGAEAFPPALYDKIRR
                     VNPDAYIMNGYGPTETTISCTMKVITDSRNITIGTPNGNVKVYIVDKENKILPDGETGE
                     LVIAGLGVGRGYMNLPDKTEAVFIDLNGERAYKTGDLARISPEGEIEFFGRIDNQIKLR
                     G"
     aSModule        8652..10346
                     /complete
                     /domains="nrpspksdomains_ctg7_8_AMP-binding.1"
                     /domains="nrpspksdomains_ctg7_8_PP-binding.1"
                     /locus_tags="ctg7_8"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       9075..9134
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg7_8_0001"
                     /evalue="3.40E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg7_8"
                     /protein_end="181"
                     /protein_start="161"
                     /score="31.8"
                     /tool="antismash"
                     /translation="CYCIYTSGSTGKPKGVLIEHI"
     CDS_motif       9525..9554
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg7_8_0002"
                     /evalue="5.60E-03"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg7_8"
                     /protein_end="321"
                     /protein_start="311"
                     /score="9.4"
                     /tool="antismash"
                     /translation="YGPTETTISCT"
     CDS_motif       9651..9740
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg7_8_0003"
                     /evalue="6.00E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg7_8"
                     /protein_end="383"
                     /protein_start="353"
                     /score="37.8"
                     /tool="antismash"
                     /translation="PDGETGELVIAGLGVGRGYMNLPDKTEAVFI"
     CDS_motif       9813..9878
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg7_8_0004"
                     /evalue="1.20E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg7_8"
                     /protein_end="429"
                     /protein_start="407"
                     /score="33.4"
                     /tool="antismash"
                     /translation="FFGRIDNQIKLRGLRIELGEIEE"
     aSDomain        10155..10346
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg7_8_PP-binding.1"
                     /evalue="2.20E-12"
                     /label="ctg7_8_PP-binding.1"
                     /locus_tag="ctg7_8"
                     /protein_end="585"
                     /protein_start="521"
                     /score="39.1"
                     /tool="antismash"
                     /translation="KIFEIVADVVENDFFGTDTSFYRAGLSSISAMKLCILISEEFGVT
                     VKTSDIHENNTVEKLEKYVM"
     CDS_motif       10449..10544
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg7_8_0005"
                     /evalue="1.90E-06"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg7_8"
                     /protein_end="651"
                     /protein_start="619"
                     /score="20.3"
                     /tool="antismash"
                     /translation="TVYNIPFLFELESSVDVQKLSDAISQMIAAHPY"
ORIGIN
        1 caattattga acagttatat acagatgctg tacgctgcag atcacagctc ctgcccggca
       61 ggtcgtttcc aaggaagaaa ttgaaatcca agggacgttc acatttccga aataaaaaag
      121 cttcttttta aaatagagcc agcattcatc aataggctta tttaagtgcg gcaattttta
      181 tgaatcttct ggtttccaac aaaacagcaa ctgttttctg tcataaaccg attaattttg
      241 tagtttgcat tagaggatat tcgctaatat gcccctaagt tgacgctaga ttgaccacat
      301 tggggtctga ccgtgcgtcc agcaaagggt atatagtccg gtgggtggaa gccccatcaa
      361 ataagctgtt aaccacagca tttgaagcga gtcttgagtc tgttacggta acgtgcaggc
      421 taagcgtaga cagcaagata gcagggatag ctatggagca ccgaaatccc aaagtatcag
      481 agggtcgaca ccgtggtcag ggtggaagac aatatatgca cttatcgtta tggtgagatt
      541 ttgcatgcct ctgcggtgtt gttgaaacta ttcatgtcag acagggacta tatgtcaact
      601 ggagaggacc tgcattttct tttcagagtg tgtaaatgaa aagtatgtcc gccaaccaaa
      661 agaagaaaga caaacgaagt gcaggtagtc ggaggcccga acagtaccgg tgaaggtatg
      721 aacaaaataa atactggagg gaagtcgaga gagaactgtg cctcgcagtt ctggcctgcg
      781 aaactatatc aaagaggaaa cattagctat acacagagat aggggaacta atggaaacga
      841 aattggcgag aatatcacaa ttatcaaaag aaaacccaga tatggtcttt acatcactgg
      901 ggcatcttat caataaggag atgcttgaga actgtcatgt ccagatggat ggaacgaaag
      961 ccgtaggaat agatggagtt accaaagaag aatacggaag aaatctggaa gaaaatctag
     1021 aagcccttat agaaagtctg aagaagaaat cctataagcc taaaccagca agactggtag
     1081 aaataccaaa ggacaatggg aagatgcggc cacttagtat ctactgttat gaagacaagc
     1141 tggtacagga agcactgcgc aggatactgg aagcagtatt cgagccaatg ttttatgatg
     1201 agatgatggg attcagaccc aacaggggct gccataaagc aatccgcaaa ctaaacataa
     1261 tgctggaaag gaaaccgacg aattatgttc tggatgcgga tataaaagga ttcttccagc
     1321 atcttgacca tgaatggatt gtgcgtttta tagaatcaag gattaaagac ccgaatatca
     1381 tccgccttgt cagacgaatg ctgaaagcag gaattatgaa taactatgaa tttgaagcaa
     1441 cagaggaagg aagtggacaa ggttccgtct gctctccgat aatttcctgt atctatatgc
     1501 actatgtgct gatatggtgg ttcagagagg tggtaacgcc gatgttaaag ggatatgcag
     1561 gtctggtggt ctatgctgat gattttgtgg tgacattcca atacaaatca gatgcagtat
     1621 ggttctatga acacttaaaa catagaatgg gacactttgg attaagcctt gaagaagaaa
     1681 agagcaggct gatagagttc ggacgatacg caaaggaaag atgcagtaaa agtggaacga
     1741 agccaggtac ctttactttc ctaggtttta cacactactg ttccaaaagc aagaatggta
     1801 gattcagagt gaagaggaaa accagtaaga aaaagtttgc gaagaaatgc agagaaataa
     1861 atcaactgat gggacacatg aaaacatgga aactgaaaga gattactgct aaactcaatc
     1921 agatactgac tggttattac cattactatg gaatcacaga caatacagaa agaataacag
     1981 catttcgata ccacgtaatg aaaagtttat tctactgtct aaatcggagg agtcaaaaga
     2041 aaagctacaa ctgggtagaa tttctgaata tgatagataa cagctatcca ctggtaagac
     2101 cccgaatata tgtcagtgta tataattgat aaatgtgaac gattcgtttc gcaaagagcc
     2161 ggatgcggga aagccgcaag tccggattct gtgaggggcg tacgaccgca aggggtgcgt
     2221 ctactcgacc catgaaatac ccggggattt atatgaagga tattgataaa agtgctttgt
     2281 aagaatcagg tagttttggt ataattcatt gtaaatgaaa atataaccga atcaggtaag
     2341 tcctctgcgg aggttgcaaa aagcgataag cagtgggtgg gaacttgctt gtatcaggag
     2401 gattgtaagc tccttctgat aaactgcgaa tatccgattg acaggcagtt aaaatcagga
     2461 ttcatgagat ggggagagat agatagtgga catttatcag attattatta cacataatcg
     2521 aagctggacg atcagggaaa ttattgcttt tgcagtggtt ttcctgatgg ccgtttttct
     2581 ggcagcagta ttattaaggc tgcataaaat agtgatcatt caggcagtct gtggactgtt
     2641 gcttctgacg tttctttcaa ttgtatttgg ttctactgtt tttacgagga ctccggggat
     2701 caggcagtat cagccggagg tattctggtc atggaaggaa atcctgggga ttggtacatg
     2761 tggcagactg ggaagtacta cgggagatgg tttactgcag gagaatctgt tgaatattct
     2821 gctacttttt ccggcaggga ttttattgcc gggggtgaca ggcagaaaac tgaaatggtg
     2881 gatgggattg cttgtgggaa ttgcggtatc atctgctatc gagattagtc agctgctgct
     2941 ttgcagaggg ttgtttgagt ttgacgatat tattcataat agtttgggat gtatgctggg
     3001 gtctttgttg gggaatagga tgttaaggtt ggtacatgga aagtaaaggg caggaccaga
     3061 tgaaaaactg acaagtcatc ttgaattgcg atttcaggaa ggtcacgttc aaaacttaac
     3121 agtttttgtg aagcattttg aaaaccgtcc ctgctatcag caggggcggc tttcatttgt
     3181 gcgcctattt attgttttcg ctgacatgaa gatagttcat aagcgcaacc tgaaaaattt
     3241 tggaacaatt gactccgttc acagcaatgt ctttttgacg taaaattgtt tataacagta
     3301 aaaatgttta acaaaatctg ttaaaatgct ataatgcaga tatgaaaaag ataatcttga
     3361 gaaaatccat aatgtatgat aaaaggatta ctataaactg gtactgtgaa aatacgacag
     3421 aagaggagta aaaagatgtt atatatagga aatcacacaa gctcatcccg gggatatctt
     3481 gcaatgggga agcagatgct ggcaaatggt ggtaacacat ttgcattttt taccagaaat
     3541 ccaagaggag ggaaagccaa agacattgat ccgcaggatg tgcaggcatt tgggcagctg
     3601 gcagaggaga atcattttgg aaagctggtg gctcatgcgc cttacactat gaactgctgc
     3661 actgccaaag aaaacctcag ggattttgcc agagaaatca tggcagatga tctgagacgt
     3721 ctggaaatga caccgggaaa ttattacaat tttcatccgg gcagtcacgt aggacagggt
     3781 gcagaagtag gaatcagtaa aattgcagaa attctcaatg aagtgctgac aaaagatcag
     3841 agtacgattg tacttctgga aactatgtca ggaaagggca cagaagtagg aagaaatttc
     3901 gaagaacttc gtcagatcat tgacaaggtg gagttaaaag ataaattagg tgtttgtctg
     3961 gatacctgtc atgtctggga tggtggatat gatattgtaa acgatcttga cagcgtattt
     4021 gaagaatttg accggataat aggtctggac agactaaaag ccatccattt aaatgacagc
     4081 atgaatcccc ttggcagcca taaggaccgc catgccagaa tcggagaagg tgaaatagga
     4141 ctggagacac ttgtccgcgt tatcaatcat cctgccacag agggaattcc gtttattctg
     4201 gagacaccaa atgacgatga gggatggact catgaaattg cgttgctcag aaatgagtat
     4261 aaacagaaat gagtataaac agaaatgagt ataaatatat ctgtccgaat cagaaagata
     4321 aattggggcg tgcagattat ggaaatgatt tttcaaacgc gctttagcgt gctgacaagt
     4381 tgtaagtgca aatcgaaaga gtaggagtga gatcaaaagg aaggaatgca gcaaagatca
     4441 gagatgcagc aaagacaagg atatcaggca gtagagaagc tgagagaaac actggacgag
     4501 aagtatctgt gggaggttat tttactctat gcaggtgaga gtttcaaaac ctatacaggg
     4561 cttccgttca cttatgaagt aagaaagggt cggaatggag actacacaag ggaattgtgg
     4621 atcgaccgta gggagaacag taagagtctg gcgttaagtt cagtgctgct ggcattgaga
     4681 aacataaaga aggtgggagc tgtggttgac agacccaaag ctctgggcga catccgcgga
     4741 gtgagttata tatatggaat gttctaccgc tttgggctga tcgatgtgcc ggatacagcc
     4801 aggcagaaga tgaagttcac aggatatatt ttttaggagg aaaggtatga acaagaagag
     4861 aaacgtggat tctgggagaa agtctgcaag accggattac attcagaaaa caatatcaca
     4921 gaaaagttca ggaaaacgca gtggaaaagt tttcttcccc aaaaccctca taaagactgg
     4981 ggggattata atttttgtac ttctgcttgg gtttgcagga aacaagtttt tcctgtctgt
     5041 cagcaaaaca gacagcggga aggtgaaggc cgtatcagct tcaggtgcag atgaggaaaa
     5101 aggaggctgg ataatcggaa aaactaaaga aaccaaagat gtggttgaaa tgaaaaagac
     5161 taaagagatt aattttcagc ctcattgtgt ggattctaca aaaccggaaa atctgatcag
     5221 ctatactaat attgaggtgg atggaaacgt acttgaaaat attggagatt ataaggctga
     5281 tggtgatatt tcctttaata taggacagga ttatacagat gtggatggga tcgtcacatt
     5341 ccgcggaaac agttttcgcg atgctccttc ccatggttat gcagatatga ctgatttcag
     5401 gctggacaaa ctgtggtctg cagatacagg ttctctttct tcgggcagtg cagtctggac
     5461 aggaagtggc tggacaggac agccgcttat gatgaaatgg cccaaagaag ttaaagcaca
     5521 tatgaatatg acagagaaag caaaggcaga tgatgaactg gttgaggtga tttatgcctg
     5581 tatggatgga tatgtgtatt ttctggatct gagaacggga gaaaagacac gtgacccatt
     5641 atatctggga tatactttta agggtgcggg tgcccttgat ccgagaggat atccgattat
     5701 gtatgttggc gccggatata acagcaacga aggaactgca aaggtatttg tagtaaactt
     5761 gctggattgt agtgttatgt atacttttgg agacaatgat gagttttcac tcagaggaag
     5821 tctgagcttt tttgacggat cagcacttgt ggatgcagag acagataccc tgatctatcc
     5881 gggagagaac ggaatcctgt atctgatcag gctgaataca aaatatgatc tgaacagtgg
     5941 gactttatcc attgatccgg gcagaactgt aaaatggcgc tactatggaa caagaagcag
     6001 tacagagtct ttctggcttg gaatggaaga cagtgcggca atctataaag gctatatatt
     6061 tatgaccgat aatgggggaa atcttatgtg tctggatctg aacactcttc agctggtatg
     6121 ggttcaggat acattggatg attctaattc aacgcctgtt ctggaaatcg aaaaaggaca
     6181 tctgtatctg tatgtaagta cttccttccg ccttggatgg agaagttatg acacagccac
     6241 tgtccctgtc tggaagattg atgcagaaac cggtgagatc gtgtggcata cagattatga
     6301 atgtactact gatgacggtg tttccggtgg agttcagtct acgattgcct gtggaaagaa
     6361 cagccttgcc gattatatat atgtgacagt ggcaaagacc tctgacaatg catccggagt
     6421 tcttgcctgt ctgagaaaat ctgacggatc taaagcatgg gaggattctt cctcatatgc
     6481 ctggtcttct ccggtgtgcg tttataacaa agacggatca ggaaaggttc tttattgcaa
     6541 cagtacaggt gatatccgcc ttcttgatgg taaaacaggt aaacaggaag atgtattatc
     6601 tgtcagcgag ggcgtgatag aggcttcccc ggctgtctac gataactatg cggttgtagg
     6661 caccagagac tgtaaaatat ggggaatcag gttacagtaa atagcaatat ttatttgctt
     6721 tctcccattc tttattaact tgccatttat cgcactaaat ggtaaaattt aaatatctta
     6781 cagttttacg gcacaatatt ttgaaaaaac tgaaaacaaa ggagaggaag cgatggaaga
     6841 gagaaataac agactgctga atgcgaagct gaacaagtat attgttccgg ggattatgat
     6901 gtctctggcg cttcagttgg gaaatatcgt agatacgata tttgtaagta acctgatcgg
     6961 ggtggaggca atgtctgcag ttaccctgag cctgcctgtg gagacgatcg ttcagctgac
     7021 aggatactgc cttggtatcg gcggttccat agcagtggga aacatgcttg gcaaacgaga
     7081 caaagaaggg gcatcgaaat tgttttctgc cacatttata gtaacacttg tggtgggaat
     7141 cattttttca atctgcgccc ttcctgcagc agaacctgtt gccagacttc tggtatcagg
     7201 tgacggtgtc ctgaccggtt ataccagaga ttacatacgt gtaagtatgc tgggggcacc
     7261 ggtgatcgga attggactga tgatggtcaa ttaccttggt gtggagaatc atccggagct
     7321 ggcatcagcc taccttatcg cagccaatgt gatcaatctt gtgctggact atatattcct
     7381 cagatatact ccgctgggga ttacaggtgc atccttatca actgttcttg gtttcctgtt
     7441 tgcaatggga atttttgtgc tttatatccg ctctgataag cgaaatctcc acctgatcct
     7501 gctaaagccg ggcgaacttg gaatcacaaa ggaagcaatc atcacaggcg tgccaatgct
     7561 gatctttatg gcagctaatt ttgtaaaggc gcttggactg aataccatta tcatgaacca
     7621 gctgggcgag gaaggtatgg cagtatttac tgtctgtgac aatgtgctgc tgatcgtcga
     7681 gatgcttaca ggcggaatca tcggtgtgat ccccaatgtg gcaggaatcc tttttggaga
     7741 gaaggactac gtgggaatcc gggttctctg taaaaagatg ctgaaataca gttacatcct
     7801 gctggctgtg atctttgtcc ttattatgct gtttaccgag gaaatcactg ttatgttcgg
     7861 aagcggcggg ggcgaactgg gtagccatat ggtccaggcg ctgcgaatct ttgctttgtg
     7921 tgtggcacct tatctgtgga ataagtttat tatcagctat tacgagtcca ttgaggagac
     7981 agccattgca agctttgcca catttctgga gaatgcggtg gtagttctgc ctgcaaccct
     8041 ggtgggaatc cttgtatgga aacagattga cgggatcggt atcgacggaa ttgcagcagg
     8101 atttgttgcc actgagatca taactgcagt tgcagcctgt attttcagaa aaatcaggca
     8161 taagaataca agcttttata ttgttcctga caaaaatccg gggattaatc tggatttttc
     8221 cattaagagt accatggagg aagcacaaac ggttcataag aggatcatag agttctgcca
     8281 ggaacaggga gcttctaaaa gcaaggcaaa tcttgccgca gtgtgtgcgg aggaaatgac
     8341 tgtaaatatt atacgattcg ggggaaaaac ctccaactgg atcgacatta acctctgtct
     8401 ggaggatgat ctctgcagac tgaggatcag agataacggt gtaaatttca accctctgga
     8461 atatcagtat gacagtgaag actttgatat acatgggatt gaacttgtca agaaggtatc
     8521 aaaatccatg gattatattc gtgcgattga tatgaataat accataatat ctttttagga
     8581 ggtacatgaa aatgaaaaat attaatgaaa ggaacaattt tgcttttgag tttcggccgg
     8641 taacagaatt gttcgaggaa caggtgaagc ttcatccaga gaaatgtgca gttgtctccg
     8701 gcaaagagag ctttacctat gcacagctca atgaacgggc caacaggatt gccaatgcac
     8761 ttgtggaaaa aggtgtcaga cgggagacca tcgtaggtgt ggttcttgag agatgctgtg
     8821 atttctatgc agtgcgacag ggtatcctga aggcaggagg tgcatttgca gttgccacat
     8881 cggattatcc tgatgacagg atccggtata tttttgagga ttcaggagct ccttttatta
     8941 tcacaacaaa ggagatcgca gaggaacgaa gggaactgtt tgctaagctt ccctgtacag
     9001 tacttctgat cgaggaactt ctggagaatg agaatataga gaatcctcag gtaaagatcg
     9061 gggagcatga tctttgttat tgtatctata cttccggttc cacaggcaag cccaagggtg
     9121 tgctgatcga acatatcaac ctttccaatt ttgtaaatcc ggatccgaaa aatgcggaaa
     9181 cttatggtta tgtaagcaga ggaagtgtat ctctttccat ggcagccatg acctttgatg
     9241 tgtctgttct ggaggaattt ctgccactta ccaacgggat gactgcggtg atcgcctctg
     9301 atgaggagat tttgaatcct cttatgctgg gtgagctgat cgtcagaaat aaagtggata
     9361 ttatgaccac aactcctact tacctgtcca atatgatcga tctgccccag cttgaaaaag
     9421 cagtttctca gattaaggtg tttgatgtag gtgcagaggc ttttcctccg gctctgtatg
     9481 acaagattcg cagagtaaac ccggatgctt acattatgaa tggttatgga cctacggaaa
     9541 ctactatcag ctgtaccatg aaggtaatta cggacagcag aaacattacc attggtacgc
     9601 ctaacggtaa tgtgaaggta tatattgtag ataaagagaa taagatcctt ccggacggag
     9661 agaccggaga gcttgtgatc gcaggactgg gcgttggcag aggttatatg aatctgccgg
     9721 ataaaacaga ggctgtattc attgatctta acggagagag agcttataag accggtgacc
     9781 ttgcaaggat cagccctgag ggtgagattg aatttttcgg aagaatagac aatcagatca
     9841 agcttcgcgg tctgaggatt gagcttggtg agatcgagga ggtgatcaat tcctatgagg
     9901 gaatcattac cagcattact ctgcctgtag ataacaaatt cctctgctgc tattttatgg
     9961 ctgaccgcca gatcaataca gaggagcttt ctgcctatgc atcagagtcc ctggctcatt
    10021 atatggttcc tgaggttttt gtccaactgg aaaagatgcc tgtgacacag aatggcaaaa
    10081 ttgataagaa agcactgcca aagccggttg cacagccaaa gaatctgaaa gaaccccaga
    10141 ctcctatgca gaagaagatt tttgaaatcg ttgcagacgt tgtggagaat gatttttttg
    10201 gaactgacac aagtttttac agggcggggc tgtcttctat cagtgccatg aagctttgta
    10261 ttctgatctc agaggaattc ggagtgactg tgaaaaccag tgatatccac gaaaacaata
    10321 cggtggagaa gctggaaaaa tatgtgatgc ttgcaccgaa gatcagaacc tatgaaaaga
    10381 gagaagttta ccctcttacc ggctcccaga agggtatttt tgcagagtgc atgaagaatc
    10441 ctgagagtac ggtatacaat attccgttcc tgtttgaact ggaaagctct gttgacgttc
    10501 agaagctgtc agatgccatt tctcagatga tcgctgcaca tccgtatctg ctgacaaagg
    10561 tttatttaag tgacagcgga gagatggtgc agaagccttg tgaggaagcc tttgtaccag
    10621 aggtggtccg gaccacaaat gagcagtttg aaaagatgaa agatgagctg gtgcgtccct
    10681 ttaagctgga aaagggacgg ctgttccggg cggggattta tgtgacagaa gacaggaaat
    10741 atctttttac agatttccac catatcctag agcgtgtctg aaaaataaaa attgcacaaa
    10801 acgcatgttt tatttccctt tttcatgata aaataaagaa aaaggggt
//
