LOCUS       c00015_3300017..        8591 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300017473.a:Ga0185331_1002736.
ACCESSION   c00015_3300017..
VERSION     c00015_3300017..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-24 04:09:12
            Original ID  :: 3300017473.a:Ga0185331_1002736
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8591
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..8591
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:4750](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(2..4750)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..8591
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..8591
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             complement(2..4750)
                     /NRPS_PKS="Domain: PP-binding (12-78). E-value: 8.6e-11.
                     Score: 34.0. Matches aSDomain:
                     nrpspksdomains_ctg15_1_PP-binding.1"
                     /NRPS_PKS="Domain: Aminotran_3 (246-577). E-value: 1.5e-55.
                     Score: 180.3. Matches aSDomain:
                     nrpspksdomains_ctg15_1_Aminotran_3.1"
                     /NRPS_PKS="Domain: Condensation_LCL (644-934). E-value:
                     2.5e-73. Score: 238.4. Matches aSDomain:
                     nrpspksdomains_ctg15_1_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1097-1511). E-value:
                     1.1e-103. Score: 338.7. Matches aSDomain:
                     nrpspksdomains_ctg15_1_AMP-binding.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013:aminotransferase class-III (Score: 281.8;
                     E-value: 1.5e-85)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_1"
                     /sec_met_domain="Condensation (E-value: 7.2e-61, bitscore:
                     194.5, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 8.9e-110, bitscore:
                     355.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1e-11, bitscore:
                     34.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKASRVDIDAFLLSFLVRALPSAPTTADLQVPFLEMGANSLVLM
                     EVQRAVEARFGITIAIPQFFQELTHAEALAEYIERNQTGNVVAADSVAPASTFAIPAMP
                     ALPAGNELEALFARQLESAAQLMQQVIAQQLAALGGAAGAGGQSAPAAAAAVQAAPAAT
                     AAAPDKPSSAAVMHKLLSPLEIRARGLTEQQSRHLEALIQRFTARTRQSKELAARYRPV
                     LADSRAAVGFRFTTKEMLYPITGRKGKGARIWDVDGNEYIDITMGQGVTLFGHHPDFID
                     AALADPENDILLLGPRPPQVGEAAELICEMTGMERVTFTNTGTEAVMAALRLARAATKR
                     NKIVMFENAYHGHADNVMGRAVWQDGKLSSVPVAPGITQGSVDDLLLLDYGSDAALDYI
                     RAHAQELAAVVIEPVQSRRPDLQPRAFLHELRRITAESGTLLVFDEMITGFRIHQGGAQ
                     AWFGVKADLATYGKVLAGGMPIGVVAGAARIMDAIDGGPWQYGDDSYPKVDRTIFGGTF
                     CQHPTAMIALLATLRHLKAAGPQLQETLNRRTHRLAAELNDYFEREEVPIKVVHFGSLF
                     RFAFSANFELLFYHLMEQGIFIWEWRNYFLSTAHIDADVDAIVAAVKASVAALRSGGFL
                     PEKAATAQAAPVPLIAAQKQLAVLAEINPQGSLAYHVSPLLKLSGDLEVAALRSAVRLL
                     MERHEALRSVIVGEAQQALPLSALPGVGELSLTELATEDALLDALAQHADRAFDLARGP
                     LFEAHLFKLGAQDYRLLLKAHHLVVDGLSMNQMVQEIAALYSAALQGTPHALPACLQAR
                     DYAAWRAAQHFPAQRDYWLDQLAGELPVLELPADRPAPPLRSFRGGRHRAEVPAELFAQ
                     IRTLSRAQGCTHFMTLFAAYALWLHRLCQQDDLIVGMPVAGRGLKGGELLVAYCTHLLP
                     IRSRLAGEQPFTAYLRSMRDTLLAAYQNQDYPFAELLDQPQLRGRRANLVSTVFNLDRP
                     GVAPPMAGLEVEWLSQPVRHTAFDLTLNLTELGERLVLECDYDLDRFDAASMARHVDSF
                     LALLAGIAAAPESSVFRLPMLAAAAQQAWLVDWNATAADYPKDRCAQELFAAQAARTPD
                     AVAIAADTATLSYAALDAAANRLAHWLQAQGVGPETVVGVCAGRTPELSVALLAVWKAG
                     GAYLPLDPSYPPQRLRFMLEDAGVKVVLTQTAHVAQVTADGVRSLALDGERALYADLPA
                     TAPPCAATADSLAYLIYTSGSTGRPKGTLIPHRGLTNYLAWALRRYEMEQGVGAPLHSS
                     ISFDATITSLFCPLLAGRTLRMLPEGGAEIDHIRAALEAGRSQPWSFVKLTPAHLELLN
                     AMLPEDALAGLTRFVVLGGEALLGRQVAPWRRGAPATRLINEYGPTETVVGCCVHEVTD
                     DDAAGSAIPIGKPIANTQLYVLDRHLQPLPPGAKGELFIGGDGVARGYHNRPELTAERF
                     IDVAQTGLAASTTIAGIPPGRLYRTGDLVRHLADGTLVYLGRIDHQIKLRGFRIELGEI
                     EAALGRQANVREALVIVQQRSAQDQRLIAYVSPMAGATLEEGALRTALANELPLHMLPA
                     RIVV"
     CDS_motif       complement(188..253)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg15_1_0007"
                     /evalue="6.00E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg15_1"
                     /protein_end="1521"
                     /protein_start="1499"
                     /score="37.5"
                     /tool="antismash"
                     /translation="YLGRIDHQIKLRGFRIELGEIEA"
     aSDomain        complement(218..1459)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg15_1_AMP-binding.1"
                     /evalue="1.10E-103"
                     /label="ctg15_1_AMP-binding.1"
                     /locus_tag="ctg15_1"
                     /protein_end="1511"
                     /protein_start="1097"
                     /score="338.7"
                     /specificity="consensus: asn"
                     /tool="antismash"
                     /translation="FAAQAARTPDAVAIAADTATLSYAALDAAANRLAHWLQAQGVGPE
                     TVVGVCAGRTPELSVALLAVWKAGGAYLPLDPSYPPQRLRFMLEDAGVKVVLTQTAHVA
                     QVTADGVRSLALDGERALYADLPATAPPCAATADSLAYLIYTSGSTGRPKGTLIPHRGL
                     TNYLAWALRRYEMEQGVGAPLHSSISFDATITSLFCPLLAGRTLRMLPEGGAEIDHIRA
                     ALEAGRSQPWSFVKLTPAHLELLNAMLPEDALAGLTRFVVLGGEALLGRQVAPWRRGAP
                     ATRLINEYGPTETVVGCCVHEVTDDDAAGSAIPIGKPIANTQLYVLDRHLQPLPPGAKG
                     ELFIGGDGVARGYHNRPELTAERFIDVAQTGLAASTTIAGIPPGRLYRTGDLVRHLADG
                     TLVYLGRIDHQIKLRG"
     aSModule        218..2818
                     /domains="nrpspksdomains_ctg15_1_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg15_1_AMP-binding.1"
                     /incomplete
                     /locus_tags="ctg15_1"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(368..457)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg15_1_0006"
                     /evalue="5.40E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg15_1"
                     /protein_end="1461"
                     /protein_start="1431"
                     /score="57.0"
                     /tool="antismash"
                     /translation="PPGAKGELFIGGDGVARGYHNRPELTAERFI"
     CDS_motif       complement(980..1039)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg15_1_0005"
                     /evalue="3.00E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg15_1"
                     /protein_end="1257"
                     /protein_start="1237"
                     /score="28.9"
                     /tool="antismash"
                     /translation="AYLIYTSGSTGRPKGTLIPHR"
     CDS_motif       complement(1232..1273)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg15_1_0004"
                     /evalue="8.20E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg15_1"
                     /protein_end="1173"
                     /protein_start="1159"
                     /score="18.9"
                     /tool="antismash"
                     /translation="LAVWKAGGAYLPLDP"
     aSDomain        complement(1949..2818)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg15_1_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="2.50E-73"
                     /label="ctg15_1_Condensation_LCL.1"
                     /locus_tag="ctg15_1"
                     /protein_end="934"
                     /protein_start="644"
                     /score="238.4"
                     /tool="antismash"
                     /translation="APVPLIAAQKQLAVLAEINPQGSLAYHVSPLLKLSGDLEVAALRS
                     AVRLLMERHEALRSVIVGEAQQALPLSALPGVGELSLTELATEDALLDALAQHADRAFD
                     LARGPLFEAHLFKLGAQDYRLLLKAHHLVVDGLSMNQMVQEIAALYSAALQGTPHALPA
                     CLQARDYAAWRAAQHFPAQRDYWLDQLAGELPVLELPADRPAPPLRSFRGGRHRAEVPA
                     ELFAQIRTLSRAQGCTHFMTLFAAYALWLHRLCQQDDLIVGMPVAGRGLKGGELLVAYC
                     THLLPIRSRL"
     CDS_motif       complement(1955..2044)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg15_1_0003"
                     /evalue="7.90E-04"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg15_1"
                     /protein_end="932"
                     /protein_start="902"
                     /score="12.0"
                     /tool="antismash"
                     /translation="DLIVGMPVAGRGLKGGELLVAYCTHLLPIRS"
     CDS_motif       complement(2369..2434)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg15_1_0002"
                     /evalue="3.70E-08"
                     /label="C3_starter_134-155"
                     /locus_tag="ctg15_1"
                     /protein_end="794"
                     /protein_start="772"
                     /score="26.2"
                     /tool="antismash"
                     /translation="AHHLVVDGLSMNQMVQEIAALYS"
     CDS_motif       complement(2636..2746)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg15_1_0001"
                     /evalue="4.10E-12"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg15_1"
                     /protein_end="705"
                     /protein_start="668"
                     /score="38.5"
                     /tool="antismash"
                     /translation="AYHVSPLLKLSGDLEVAALRSAVRLLMERHEALRSVIV"
     aSDomain        complement(3020..4012)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg15_1_Aminotran_3.1"
                     /evalue="1.50E-55"
                     /label="ctg15_1_Aminotran_3.1"
                     /locus_tag="ctg15_1"
                     /protein_end="577"
                     /protein_start="246"
                     /score="180.3"
                     /tool="antismash"
                     /translation="KGKGARIWDVDGNEYIDITMGQGVTLFGHHPDFIDAALADPENDI
                     LLLGPRPPQVGEAAELICEMTGMERVTFTNTGTEAVMAALRLARAATKRNKIVMFENAY
                     HGHADNVMGRAVWQDGKLSSVPVAPGITQGSVDDLLLLDYGSDAALDYIRAHAQELAAV
                     VIEPVQSRRPDLQPRAFLHELRRITAESGTLLVFDEMITGFRIHQGGAQAWFGVKADLA
                     TYGKVLAGGMPIGVVAGAARIMDAIDGGPWQYGDDSYPKVDRTIFGGTFCQHPTAMIAL
                     LATLRHLKAAGPQLQETLNRRTHRLAAELNDYFEREEVPIKVVHFGSLFRF"
     misc_feature    complement(4433..4435)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        complement(4517..4714)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg15_1_PP-binding.1"
                     /evalue="8.60E-11"
                     /label="ctg15_1_PP-binding.1"
                     /locus_tag="ctg15_1"
                     /protein_end="78"
                     /protein_start="12"
                     /score="34.0"
                     /tool="antismash"
                     /translation="LLSFLVRALPSAPTTADLQVPFLEMGANSLVLMEVQRAVEARFGI
                     TIAIPQFFQELTHAEALAEYIE"
     aSModule        4517..4714
                     /domains="nrpspksdomains_ctg15_1_PP-binding.1"
                     /incomplete
                     /locus_tags="ctg15_1"
                     /tool="antismash"
                     /type="unknown"
     CDS             complement(4747..5934)
                     /locus_tag="ctg15_2"
                     /transl_table=11
                     /translation="MTAAAADIVFFDATRIDAGCRGFSGVAAVGRHLYFAPLNNGDFHG
                     RVLRHDTAGDFSDPAAWSVFDCAALDPAARGFVDVLSDGRHLYFVPFCNGRHHGRIVRH
                     DTQGGFHDPASWQVFDVQALNSSARGFVSGCFDGRHVYFAPYQLDHVTTNGLIARFDTQ
                     GDFADPAGWQCFDATQIHPDCRGFHSAIRDDAGYVHFVPYLREGKSYNGRLLRHDTRKD
                     FAAPAAWESFDLTLLDPGCQGYVGGCARDGLLYLAPYFDGADRHGRVLRFDTRAALADR
                     TAWTLFDCATLDPGSRGFFGAVADADHLYLVPHCRGVGQYHGQLTRYRRAMDFAAPAAW
                     SFHDLGRDHPLARGFIGGVRHGEHLYLAPFETDAGCHSGLVARLRTDAEHLWSST"
     CDS             complement(5938..7011)
                     /NRPS_PKS="Domain: FkbH (19-138). E-value: 1.6e-19. Score:
                     61.9. Matches aSDomain: nrpspksdomains_ctg15_3_FkbH.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1256:FkbH like protein (Score: 449.1; E-value:
                     1.4e-136)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg15_3"
                     /transl_table=11
                     /translation="MTVTSQAEVLREEKKKRSIKCVVWDLDNTVWQGTLLEGGVTGLRP
                     GVVDAMRALDERGILQSVASKNDHAAAWAQLEAYGLADYFLYPQIGWGAKSGSVERIAK
                     DLNIGIDSFAFIDDQAFEREEVAFAQPAVLCLDAEEIDAMLARPEFNPRFVTEDSRRRR
                     AMYQADIARKQVEEHFDGPQEAFLASLEMRLRIAPAQEEDLKRAEELTLRTNQLNTTGY
                     TYSYDELDFFRGSPDHRLLIAGLDDRHGPYGKIGLVLIECRDGEWMVKLLLMSCRVMAR
                     GVGTVLINHLRNEARRHGVRLLAEMLPNERNRMMYMTYKFNHFRELEKREDGLVIFEND
                     LSTVHAFPGYMQIEIGE"
     aSDomain        complement(6598..6954)
                     /aSDomain="FkbH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg15_3_FkbH.1"
                     /evalue="1.60E-19"
                     /label="ctg15_3_FkbH.1"
                     /locus_tag="ctg15_3"
                     /protein_end="138"
                     /protein_start="19"
                     /score="61.9"
                     /tool="antismash"
                     /translation="KCVVWDLDNTVWQGTLLEGGVTGLRPGVVDAMRALDERGILQSVA
                     SKNDHAAAWAQLEAYGLADYFLYPQIGWGAKSGSVERIAKDLNIGIDSFAFIDDQAFER
                     EEVAFAQPAVLCLDAE"
     CDS             complement(7008..8177)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 408.6; E-value:
                     4.2e-124)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg15_4"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 3.5e-33, bitscore:
                     103.4, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 4.6e-22, bitscore:
                     66.9, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.3e-47, bitscore:
                     150.4, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDQFLSEAQRQAREGFRAFVDEFVMPVADEHDRQQAMPDELIQCI
                     AKMGYLGGIVPTQYGGGGMDALTWGLLCEEVGRGSASLLSLLTVHGMVCQALIKWGTDA
                     QRQRWLPLLATGERIGAFALTEPNVGSDAASIESMATAEGTDWVIDGRKRWISFGQAAN
                     LLLVIAKVEGKAAAFLVERGTEGFATEPITGMLGFRAAMLADVFLDCCRVPGDHLVGRV
                     GFGFSHVAGAALDHGRFCVAWGCLGLARGALEASLAYTSERKQFGAPLKNHQLIQELVA
                     DMITQVGAARALCRQAAALKQAGDPALIMETSIAKYFTSRVAVKAASDAVQIHGANGCS
                     DRYPVQRYLRDAKIMEIIEGSNQMQQIIIAKHGYHAFRFNKQATRGEGT"
     CDS             complement(8188..8445)
                     /NRPS_PKS="Domain: PP-binding (11-75). E-value: 9.8e-10.
                     Score: 30.6. Matches aSDomain:
                     nrpspksdomains_ctg15_5_PP-binding.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1147:putative acyl carrier protein (Score: 86.1;
                     E-value: 2e-26)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg15_5"
                     /sec_met_domain="PP-binding (E-value: 1.2e-10, bitscore:
                     30.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDAASAKAKVGQFVSEYLSNAEVDPELDLFASGMVNSLFAMQLVL
                     FVEKDFGIAVANEDLDYQNFRSIAAICDFVGRKLGFATAA"
     aSDomain        complement(8221..8412)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg15_5_PP-binding.1"
                     /evalue="9.80E-10"
                     /label="ctg15_5_PP-binding.1"
                     /locus_tag="ctg15_5"
                     /protein_end="75"
                     /protein_start="11"
                     /score="30.6"
                     /tool="antismash"
                     /translation="QFVSEYLSNAEVDPELDLFASGMVNSLFAMQLVLFVEKDFGIAVA
                     NEDLDYQNFRSIAAICDFVG"
     aSModule        8221..8412
                     /domains="nrpspksdomains_ctg15_5_PP-binding.1"
                     /incomplete
                     /locus_tags="ctg15_5"
                     /tool="antismash"
                     /type="unknown"
     CDS             complement(8459..8590)
                     /locus_tag="ctg15_6"
                     /transl_table=11
                     /translation="LYSIEVLHESYNDSKYRPCPLLKKMVDAGLLGRKSGQGFYKYR"
ORIGIN
        1 gcacgacgat gcgcgccggc agcatgtgca gcggcagctc attggccagc gcggtacgca
       61 gggcgccctc ctccaatgtc gcgcccgcca tcggcgaaac gtaggcaatc agccgctggt
      121 cctgcgcgct gcgctgctgc acgatgacca gcgcctcgcg cacgttcgcc tgtcggccca
      181 gcgcggcctc gatctcgccg agctcgatgc ggaagccgcg cagcttgatc tggtggtcga
      241 tgcggccgag atagacgagc gtgccatcgg ccaggtggcg caccaggtcg ccggtgcggt
      301 agagccggcc ggggggaatg ccggcaatag tagtcgatgc cgccagcccg gtctgcgcca
      361 cgtcgatgaa gcgctcggcc gtgagttcgg gacgattgtg atagccgcgc gccacgccgt
      421 cgccgccgat gaacagttcg cccttggcgc cgggtggcag cggctgcaga tgacggtcga
      481 gcacgtaaag ctgcgtgttg gcgatgggtt tgccgatggg gatggcgctg cccgcggcat
      541 cgtcatccgt cacctcatgc acgcagcagc cgaccacggt ttcggtcggg ccgtattcgt
      601 tgatcagccg cgtcgccggc gcgccgcgcc gccagggcgc gacctgccgg ccgagcagcg
      661 cctcgccgcc gaggacgacg aagcgcgtca ggccggccag cgcgtcttcg ggcaacatgg
      721 cgttgagcag ttccagatgg gccggcgtca gcttgacgaa gctccagggc tggctgcgtc
      781 cggcttccag cgcggcgcgg atgtggtcga tctccgcccc tccttccggc agcatgcgca
      841 gcgtgcggcc ggccagcagc gggcagaaca ggctggtgat ggtggcgtcg aagctgatcg
      901 aggaatgcag cggcgcaccg acgccctgct ccatttcata gcggcgcagc gcccaggcga
      961 ggtaattcgt cagcccgcga tgggggatca gcgtgccctt gggccggccg gtcgaaccgg
     1021 aggtgtagat gagataggcg aggctgtccg ccgtggcggc gcacggcgga gcggtggccg
     1081 ggaggtcggc gtagagcgcg cgctcgccgt cgagcgctag gctgcgcacg ccgtcggcgg
     1141 tcacttgcgc cacgtgcgcc gtctgcgtca gcacgacctt cacgccggca tcttcgagca
     1201 tgaagcgcag gcgctgcggc gggtaggagg gatcgagcgg caggtaggcg ccgccggcct
     1261 tccacacggc gagcagcgcg acggagagtt cgggcgtgcg gccggcgcag acgccgacca
     1321 ccgtctccgg cccgacgccc tgcgcctgca gccagtgggc aaggcggttg gcggcggcat
     1381 cgagtgcggc gtagctcaag gtcgccgtgt cggcggcgat ggcgacggca tcgggcgtgc
     1441 gcgccgcctg cgcggcgaag agttcttgcg cgcagcggtc cttcggatag tcggcggcgg
     1501 tggcgttcca gtcgaccagc catgcctgct gcgcggcggc ggcgagcatg ggcaggcgga
     1561 acaccgagct ctccggcgcg gcggcgatgc cggcgagcag cgcgaggaaa ctgtcgacgt
     1621 ggcgcgccat gctcgccgcg tcgaagcggt cgaggtcgta gtcgcattcg agcaccagcc
     1681 gctcgccgag ttcggtgagg ttgagcgtga ggtcgaaggc ggtgtggcgc accggctgcg
     1741 acagccactc gacctccagc ccggccatcg gcggcgcgac gccggggcgg tcgaggttga
     1801 agacggtgga cacgaggttg gcgcgccgtc cgcgcagttg cggctggtcg agcagttcgg
     1861 cgaagggata gtcctggttc tggtaggcgg ccagcagcgt gtcgcgcatg ctgcgcaggt
     1921 aggccgtgaa gggctgctcg ccggcgaggc ggctgcgaat cggcagcagg tgggtgcagt
     1981 aggcgacgag gagctcgccg cccttcaacc cgcgcccggc gaccggcatg ccgacgatga
     2041 ggtcgtcctg ctggcagagg cggtgcagcc agagcgcgta ggcggcgaac agggtcatga
     2101 agtgggtgca gccctgcgcg cgggagagcg tgcggatctg cgcgaagagt tccgccggca
     2161 cctcggcgcg gtggcgcccg ccgcggaagc tgcgcagcgg cggcgccggg cggtcggccg
     2221 ggagttcgag caccggcagt tcgcccgcaa gctggtcgag ccagtagtcg cgctgcgccg
     2281 ggaagtgctg cgccgcgcgc caggcggcgt agtcgcgcgc ctgcaggcac gccggcagcg
     2341 cgtgcggcgt gccctgcagc gcggcgctgt agagcgcggc aatttcctgc accatctggt
     2401 tcatcgacag gccgtcgacg acgaggtggt gcgccttgag caggaggcgg taatcctgcg
     2461 cgccgagctt gaacagatgg gcttcgaaga gcgggccgcg cgcgaggtcg aaggcgcggt
     2521 cggcgtgctg cgccaaggcg tccagcagcg cgtcttccgt ggcgagctcg gtgagcgaga
     2581 gttcgcccac gccgggcaag gcggacaagg gcagcgcctg ctgggcctcg ccaacgatga
     2641 cgctgcgtag cgcttcgtgg cgctccatca gcaggcgcac ggcgcttcgc agcgcggcga
     2701 cttcgaggtc gccgctcagc ttgagcagcg ggctgacgtg gtaggcgagc gagccttgcg
     2761 ggttgatctc ggccagcacg gcgagctgct tctgcgcggc gatcaggggc acgggagcgg
     2821 cctgcgctgt cgcggccttc tcgggcagga agccgccgct gcgcaaggcg gcgacgctgg
     2881 ccttgaccgc ggcgacgata gcatcgacgt cggcgtcgat gtgcgcggtg gagaggaagt
     2941 agttgcgcca ctcccagatg aagatgccct gctccatcag gtggtagaag agcagttcga
     3001 agttggcgct gaaggcgaag cggaacagcg agccgaagtg cacgaccttg atcggcacct
     3061 cttcgcgttc gaagtagtcg ttgagctcgg ccgccaggcg gtgggtgcgg cggttcagcg
     3121 tctcctgcag ttgcgggccg gcggccttga ggtggcgcag cgtggcgagc agcgcgatca
     3181 tcgccgtcgg gtgctggcag aaggtgccgc cgaagatggt gcggtcgact ttgggatagc
     3241 tgtcgtcgcc gtactgccat ggcccgccgt cgatggcgtc catgatgcgc gccgcgccgg
     3301 cgacgacgcc gatgggcatg ccgccggcga ggaccttgcc gtaggtggcg aggtcggcct
     3361 tgacgccgaa ccaggcctgg gcgccgccct ggtggatgcg gaagccggtg atcatctcgt
     3421 cgaagaccag cagcgtgccc gactcggccg tgatgcgccg cagttcgtga aggaaggcgc
     3481 gcggttgcag gtcggggcgg cggctctgca ccggttcgat gacgacggcg gcgagttcct
     3541 gggcgtgggc gcggatgtag tccagcgccg cgtccgagcc gtagtcgagc agcagcaggt
     3601 cgtccaccga gccctgggtg atgccgggcg cgacgggcac cgaggacagc ttgccgtcct
     3661 gccacaccgc gcgtcccatg acgttgtcgg catggccgtg ataggcgttc tcgaacatga
     3721 cgatcttgtt gcgcttcgtt gccgcgcgcg ccaggcgcag cgccgccatc accgcctcgg
     3781 tgccggtgtt ggtgaaggtg acgcgttcca tgccggtcat ctcgcagatc agttcggcgg
     3841 cctcgccgac ctgcggcggt cgcgggccga gcagcaggat gtcgttctcc ggatcggcca
     3901 gcgcggcgtc gatgaagtcg ggatggtggc cgaacagcgt aacgccctgc cccatcgtga
     3961 tatcgatgta ttcgttgccg tccacatccc agatgcgcgc acccttcccc ttgcggccag
     4021 taatcgggta gagcatttcc ttggtggtga agcggaaacc gacggcggcg cggctgtcgg
     4081 ccagcaccgg gcggtagcgc gccgcgagtt ccttcgactg gcgcgtgcgc gcggtgaagc
     4141 gctggatcag cgcttcgagg tggcggctct gctgttcggt caggccgcgc gcgcggattt
     4201 ccagcggcga gagcagcttg tgcatgacgg cggcggagga cggcttgtcc ggcgccgcgg
     4261 cagttgcggc cggtgcggct tgcacggcag ccgccgcagc aggagcggac tgcccgcccg
     4321 cgccagccgc gccacccagg gcggcgagct gctgggcaat gacctgctgc atcagctgcg
     4381 ccgcgctttc gagctggcgc gcgaacaggg cttcgagttc gttgcccgcg ggtaaggcgg
     4441 gcatggcggg aatggcaaaa gtcgacgccg gcgccacgct atccgcggcg acgacattac
     4501 cggtctggtt gcgctcgatg tactcggcca gcgcttcggc gtgggtcagt tcctggaaga
     4561 actgcgggat ggcgatggtg atgccgaagc gcgcctcgac ggcgcgctgc acttccatca
     4621 gcaccagcga gttggcgccc atttcgagga agggcacctg caggtcggcc gtggtcggcg
     4681 cggacggcag cgcgcgcacg aggaaactga gcaggaacgc atcgatgtcg acgcggctgg
     4741 ccttggtcat gtggaactcc aaagatgttc ggcgtcggtg cgcaggcgcg cgaccaggcc
     4801 gctgtggcag ccggcgtcgg tctcgaaggg cgcgaggtag agatgctcgc cgtgccgcac
     4861 gccgccgatg aagccgcgcg ccagcggatg gtcgcggccg aggtcgtgaa aactccaggc
     4921 cgccggagcg gcgaaatcca tggcgcggcg atagcgcgtg agctggccgt gatactggcc
     4981 gacgccgcgg caatgcggaa ccaggtagag gtggtcggcg tcggcgaccg cgccgaagaa
     5041 gccgcggctg ccgggatcga gcgtcgcgca gtcgaacagc gtccaggccg tgcggtcggc
     5101 cagcgcggcg cgcgtgtcga aacgcaatac gcggccgtgg cggtcggcgc cgtcgaaata
     5161 aggcgcaagg tagagcaggc cgtcgcgcgc gcagccgccg acatagccct ggcagccggg
     5221 gtcaagcagc gtcaggtcga agctctccca ggcggcggga gcggcgaaat ccttgcgcgt
     5281 gtcgtggcgc agcagacggc cgttgtagct tttgccctcg cgcaggtagg gcacgaaatg
     5341 gacgtagccg gcatcgtccc ggatcgccga gtggaagccg cgacagtcgg gatggatttg
     5401 cgtggcgtcg aagcactgcc agcccgccgg atcggcgaag tcaccctgtg tgtcgaagcg
     5461 cgcgatcagg ccgttggtcg tgacgtggtc gagctggtag ggcgcgaaat agacatggcg
     5521 gccatcaaag caaccagaga cgaatccgcg cgcagaggaa ttcagtgcct gcacatcgaa
     5581 gacttgccag ctcgccggat cgtggaatcc gccttgcgta tcgtggcgta cgatgcggcc
     5641 gtggtgccgg ccgttgcaga agggcacgaa gtagagatgg cggccgtcgc tcagcacatc
     5701 gacgaagccg cgcgccgccg ggtcgagcgc ggcgcagtcg aagacggacc aggcggctgg
     5761 atcgctgaag tcgcccgccg tgtcgtggcg cagcacgcgg ccgtggaagt cgccgttgtt
     5821 gagcggcgca aaatagagat ggcggccgac ggcggcgacg ccggaaaagc cgcggcagcc
     5881 cgcgtcgatg cgcgtcgcgt cgaagaacac aatgtctgcg gctgccgccg tcatgcccta
     5941 ctccccgatc tcgatctgca tatagccggg gaaggcatgc acggtggaca ggtcgttctc
     6001 gaagatcacc agcccgtcct cgcgcttttc cagctcgcgg aagtggttga acttgtaggt
     6061 catgtacatc atgcggttgc gctcgttggg cagcatctcg gcgagcaggc gcacgccgtg
     6121 gcgacgcgcc tcgttgcgca ggtggttgat cagcacggtg ccgacgccgc gcgccatgac
     6181 gcggcaggac atcagcagca gcttgaccat ccactcgccg tcgcggcatt cgatcagcac
     6241 caggccgatc ttgccgtagg ggccatgcct gtcgtcgagg ccggcgatca gcaggcggtg
     6301 gtcgggcgag ccgcggaaga aatccagttc gtcgtagctg taggtgtagc ccgtggtgtt
     6361 gagctggttg gtgcgcagcg tcagttcttc ggcgcgtttc aaatcttcct cctgcgccgg
     6421 cgcgatgcgc agccgcattt cgagcgaggc aaggaaggct tcctgcgggc cgtcgaaatg
     6481 ctcctcgacc tgcttgcggg cgatgtcggc ctggtacatc gcgcggcggc ggcgcgaatc
     6541 ctcggtgacg aagcgcgggt tgaactcggg acgcgcgagc atcgcgtcga tctcctccgc
     6601 gtcgaggcac agcacggccg gctgggcgaa ggcgacttcc tcgcgttcga aagcctggtc
     6661 gtcgatgaag gcgaagctgt cgatgccgat gttgaggtcc ttggcgatgc gctccaccga
     6721 gcccgacttg gcgccccagc cgatctgcgg atagaggaaa tagtcggcga ggccgtaggc
     6781 ttcgagttgc gcccaggcgg cggcgtggtc gttcttcgag gcgaccgatt gcaggatgcc
     6841 gcgttcgtcg agcgcgcgca tggcgtcgac gacgccgggg cgcaggccgg tcacgccgcc
     6901 ttcgagcagc gtgccttgcc agaccgtgtt gtcgaggtcc cagaccacgc acttgatgct
     6961 gcgttttttc ttttcctcgc gcagcacttc ggcctgactc gttaccgtca tgtcccctcc
     7021 ccgcgcgtcg cctgcttgtt gaagcggaag gcgtggtagc catgcttggc gatgatgatc
     7081 tgctgcatct ggttgctgcc ttcgatgatc tccatgatct tggcgtcgcg caggtagcgc
     7141 tgtaccggat agcggtcgga acagccgttg gcgccgtgga tctgcaccgc gtcgctggcc
     7201 gctttcacgg cgacgcgcga ggtgaagtac ttggcgatgg aggtttccat gatcagcgcc
     7261 gggtcgcccg cctgcttgag cgccgccgcc tggcggcaca gcgcgcgcgc ggcgccgacc
     7321 tgggtgatca tgtcggcgac cagttcctgg atcagctggt ggttcttcag cggcgcgccg
     7381 aactgcttgc gctcgctggt gtaagcaagg ctggcttcca gcgcgccgcg cgccagcccg
     7441 aggcagcccc aggcgacgca gaagcggcca tggtcgagcg ccgcgccggc gacgtgcgag
     7501 aagccgaagc cgacgcgccc gaccagatgg tcgccgggca cgcggcagca atcgaggaaa
     7561 acgtcggcca gcatcgcggc acggaagccg agcatgccag tgatcggttc ggtggcgaaa
     7621 ccttcggtac cgcgttccac cagaaacgcc gcggctttcc cctccacctt ggcgatcacc
     7681 agcagcaggt tggccgcctg gccgaaggag atccagcgct tgcggccgtc gatcacccag
     7741 tccgtaccct ccgccgtggc catgctttcg atgctcgccg cgtcgctgcc gacgttcggt
     7801 tcggtcaggg cgaaggcgcc gatgcgttcg cccgtcgcca gaagcggcag ccagcgctgg
     7861 cgttgcgcat cggtacccca cttgatcagc gcctggcaga ccatgccatg aaccgtcagc
     7921 agcgagagca gcgaagcgct gccgcgtccg acttcctcgc agagcaggcc ccaggtcagc
     7981 gcatccatgc cgccgccgcc atactgcgtc ggtacgatgc cgccgagata gcccatcttg
     8041 gcgatgcact ggatcaactc gtccggcatc gcctgctggc ggtcgtgctc gtccgccacc
     8101 ggcatcacga attcatcgac aaaggcgcga aaaccctcgc gcgcctggcg ttgcgcttcg
     8161 ctcaggaact ggtccatgga gccctcctca ggcggcggtg gcgaaaccga gcttccggcc
     8221 gacgaaatcg caaatcgcgg caatcgagcg aaagttctgg taatcgagat cctcgttagc
     8281 aacggcaatg ccgaagtcct tctcgacgaa cagcaccagt tgcatggcga acagcgaatt
     8341 gaccatgccc gaggcgaaaa ggtcgagctc gggatcgacc tcggcattgc tcaggtattc
     8401 gctgacgaac tggccgacct tggcctttgc gcttgctgca tccatcgcat tctccctgtt
     8461 agcgatattt gtagaaaccc tggccgctct tgcggcccag caggccggcg tccaccatct
     8521 tcttcaacag cgggcagggc cggtatttgc tgtcattgta gctttcgtgc aatacctcaa
     8581 tggaataaag a
//
