LOCUS       c00173_3300017..        8634 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300017473.a:Ga0185331_1002719.
ACCESSION   c00173_3300017..
VERSION     c00173_3300017..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-24 04:09:12
            Original ID  :: 3300017473.a:Ga0185331_1002719
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8634
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..8634
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3592:8074](-)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(3593..8074)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..8634
                     /SMILES="CC(O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..8634
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     CDS             222..1439
                     /gene_functions="other (smcogs) SMCOG1130:transposase
                     (Score: 380.3; E-value: 1.3e-115)"
                     /gene_kind="other"
                     /locus_tag="ctg173_1"
                     /transl_table=11
                     /translation="MAAIDVSASKELLPGLLGSQDGLAKLVEAVLNQILEAQVTETLGA
                     ERHERSDDRLGYRNGHRPRTLYTRVGPITLLVPQTRDGSFSTDIFKRYQRSEQAFVLAL
                     MEMVVQGVSTRKVSTITEELCGASFSKSTVSSLCSGLDVRVRAFNERRLEGEYPFVLVD
                     AMFIQSRQEDRVLMRTVLIVSGVRSDGMREILGVKIGDSESFATWDETFRWLRGRGLKG
                     VAFVISDQHGGLREAVAKHFHDATWQRCQVHLMRNILGSCGSKIRAEVTVAAKLVFQAA
                     DLPEARRRLTEFSERFAKTAPKAVACLEAGFEDAMAVMALPEKYRKRLRTTNMQERLNE
                     EIRRRERVIRIFPNDESALRLIGALLAEQNETWLERKYLDMQEYHEWAASCAAAREGNN
                     VVALSG"
     CDS             complement(1450..3564)
                     /gene_functions="other (smcogs) SMCOG1037:heavy metal
                     translocating P-type ATPase (Score: 377.9; E-value:
                     1.7e-114)"
                     /gene_kind="other"
                     /locus_tag="ctg173_2"
                     /transl_table=11
                     /translation="MLDILIILGGAVYAGINAMRERSAAVQGVKPDIAAAVSAAAVPVA
                     AGQSAVVPVATSAAYQMLDTEKADHYLQVAGVALGTSALALVFPPAGLVAVSLLTYLAL
                     PLYKSATIGALVERRPRSSMVGAVLTLASLGSGYYLLVAGSSLGFFLSYKLMIKTQAGS
                     GPRVARILGASPRQVWLAYADSEVGVPFESLRAGDVIVLRAGELVPIDGTVVQGMASVD
                     QRTLTGESHVVDKIPGDIVLASTTVVAGKLHVRVEKAGEQTTVAHIERILDDTADYTAA
                     VEQKAGAVCDRLAGPTLAAGGATALLLGPVHGVALIGCNLTEVNRATTPLTMLNYLDLS
                     ARQGILVKDGRSLELLSGIDTVVFDKTGTLTLEQPHIGEIHCLGDLDADAVLCLAAAAG
                     RQQTHPVARAVVLAATERGLSLPELDDARYEIGYGVKVVLGKRNVCLGSRRFMHKEGIH
                     VADPEGLATLQKHSEQRGCSLLFVAADALLVGVIEIHSTLRPEAFAVVKRLKTRGLKLA
                     IVSGDAEAPTRGIARALGIEDCHAGVLPDEKAAIVRQLREQGRSICFVGDGINDTVALK
                     TATVGISLSGSANVALDTAGIILMEQNLDRLEVLFDLAAEMERYRQRGYYATLVPGAAG
                     AAGVLFFGMGLPAALLLDMFGIGAALGTAMWPKYVARSTIQPLSRKASSSSALSQSSPK
                     FAVNLLRAGQ"
     misc_feature    complement(1501..1503)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(1612..1614)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(2416..2418)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(3163..3165)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             complement(3593..8074)
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (11-446). E-value:
                     5.5e-149. Score: 488.4. Matches aSDomain:
                     nrpspksdomains_ctg173_3_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (542-825). E-value: 2.9e-67.
                     Score: 218.8. Matches aSDomain:
                     nrpspksdomains_ctg173_3_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_KR (1126-1319). E-value: 4.4e-48.
                     Score: 155.3. Matches aSDomain:
                     nrpspksdomains_ctg173_3_PKS_KR.1"
                     /NRPS_PKS="Domain: PCP (1411-1478). E-value: 1.4e-24.
                     Score: 77.8. Matches aSDomain:
                     nrpspksdomains_ctg173_3_PCP.1"
                     /NRPS_PKS="type: PKS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 252.5; E-value:
                     1.3e-76)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg173_3"
                     /sec_met_domain="PP-binding (E-value: 9.1e-19, bitscore:
                     56.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 2.3e-68, bitscore: 218.8,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 3.9e-156, bitscore:
                     508.2, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 3.4e-42, bitscore:
                     132.5, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VSEHDHDDFGLVAIVGMALRVPGATNLEQFWDKLKHGVESTTFFS
                     DAELRAVGVSEAELADPDYVKACGKLEGAALFDAAFFDLTPREAEILDPQHRQLLECGW
                     EALEHAGYAPGSAAMQTVQESGRIGVFAGVGLNGYLIHQLVNRHDLIETLGGWQITLGN
                     DKDFAATRLAYKLDLRGPAANVSTACSTSLVAVGMGCQSLLAYQCDMILAGGCSIHLPQ
                     DRGYRYHSGGTLSPDGKCRAFDAQAQGTFDANGAAVLVLKRLEDARRDGDTVHAVIRGC
                     AINNDGAGKVGYTAPSVEGQAAVIREAQEMAAVDATTIGYVETHGTGTDLGDLVEVAAL
                     TEAFRHSGAGVGWCGIGSLKSNLGHLDTAAGAASLIKTVLGLQHDQIPPTLHFTAPNPK
                     LELATSPFYVNAALRDWPRLGGAPRRAGVSSFGIGGTNAHVVVEEAPPVLASSPGRPWQ
                     LLPLSARGAVALEAGEQRLAAHLLQSTDAFADITYSLQTGRAPFARRRAVVARSAAEAA
                     QALAAERAPRVFSGQAGEHAPAVVFLFPGQDAQFPGMAQTLYRDEPLFRAEVDACAAQL
                     RERHGIDLMPRLFSPGGDADPAYATDPLPLFVLEYSLVQVWLALGVRPQAMLGYSLGEY
                     ACAVLAGVMSRDDALALAVAGSRLLSLVKPGALLAVSLPESELRPLLEPGLEIAMVMAP
                     RQCVVGGAAEAVQALERRLVAQGAACLSSQLGLPFHTAHMDAFLAPYREEVRKVKLAPP
                     RLPYVSCVSGDWITAAEATDPEHYLQLGRQAVHLAQGLEKVFTLPAVQAGGLLLEVGPS
                     QTITSLVYLQAQRPPELAALSTLCDPRFQSAETAESAFPTALAKLWVAGVDIRWSALYA
                     HETRRRVPLPTYAFEHQRYWVEAAPQAATLPPPSVGKLTNQEQWFHAPLWQERPALAAG
                     DATGEWLLVGGSEIAVELATRLRAAGASVEQLAALPTDWAALLDARIAAGRRPARIVQL
                     GLFDCADTDAARLDAGFHSLLALGRAVGARWFAEALRIDLVAPRLCALGASVPAPAAAA
                     AMGPLRVLPQEIPNLRCRAIDIEIPDQPWRRARLLDALLAELTAGDESAVALRGTQRWV
                     ESFVPHLPSESAALPLRPGGVYLITGGLGNIGLALARRIAQRAPGARLLLTGRAGLPND
                     PSRDDALQAARRAACAEIAKLGVEVRIVAADVTDADAMATLLAVTERGWGPVNGVIHAA
                     GLVGQASFATVAESTPEFCARQIGPKLGGARVLEQVLGDRPLDFCLLCSSLSPILGGLG
                     FAAYAAANAALDACAAAHNLTHPVRWLTVNWEGWRFDESPTTGLTGAAGAGAAVEELGL
                     TAEEGAAAFERILAMPNPERIALSTSDLGQRLRQWVQMEAAPSVVPAAARHARPSLMGA
                     YVAPTGATQQTIATLWEQLLGIDGVGAEDSFFELGGNSLLLTQLLAQIRKRFRVELSLA
                     VLFERPTITAIAALVDAAIGTGQEEDREEGEL"
     aSDomain        complement(3641..3841)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg173_3_PCP.1"
                     /evalue="1.40E-24"
                     /label="ctg173_3_PCP.1"
                     /locus_tag="ctg173_3"
                     /protein_end="1478"
                     /protein_start="1411"
                     /score="77.8"
                     /tool="antismash"
                     /translation="QTIATLWEQLLGIDGVGAEDSFFELGGNSLLLTQLLAQIRKRFRV
                     ELSLAVLFERPTITAIAALVDAA"
     aSModule        3641..8041
                     /complete
                     /domains="nrpspksdomains_ctg173_3_PKS_KS.1"
                     /domains="nrpspksdomains_ctg173_3_PKS_AT.1"
                     /domains="nrpspksdomains_ctg173_3_PKS_KR.1"
                     /domains="nrpspksdomains_ctg173_3_PCP.1"
                     /locus_tags="ctg173_3"
                     /monomer_pairings="mal -> ohmal"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(4118..4696)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg173_3_PKS_KR.1"
                     /evalue="4.40E-48"
                     /label="ctg173_3_PKS_KR.1"
                     /locus_tag="ctg173_3"
                     /protein_end="1319"
                     /protein_start="1126"
                     /score="155.3"
                     /specificity="KR stereochemistry: (unknown)"
                     /specificity="KR activity: active"
                     /tool="antismash"
                     /translation="GVYLITGGLGNIGLALARRIAQRAPGARLLLTGRAGLPNDPSRDD
                     ALQAARRAACAEIAKLGVEVRIVAADVTDADAMATLLAVTERGWGPVNGVIHAAGLVGQ
                     ASFATVAESTPEFCARQIGPKLGGARVLEQVLGDRPLDFCLLCSSLSPILGGLGFAAYA
                     AANAALDACAAAHNLTHPVRWLTVNWEGWRF"
     CDS_motif       complement(4172..4276)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg173_3_0008"
                     /evalue="4.80E-11"
                     /label="PKSI-KR_m4"
                     /locus_tag="ctg173_3"
                     /protein_end="1301"
                     /protein_start="1266"
                     /score="35.2"
                     /tool="antismash"
                     /translation="LDFCLLCSSLSPILGGLGFAAYAAANAALDACAAAH"
     CDS_motif       complement(4595..4693)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg173_3_0007"
                     /evalue="2.80E-08"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg173_3"
                     /protein_end="1160"
                     /protein_start="1127"
                     /score="26.4"
                     /tool="antismash"
                     /translation="VYLITGGLGNIGLALARRIAQRAPGARLLLTGRA"
     aSDomain        complement(5600..6448)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg173_3_PKS_AT.1"
                     /evalue="2.90E-67"
                     /label="ctg173_3_PKS_AT.1"
                     /locus_tag="ctg173_3"
                     /protein_end="825"
                     /protein_start="542"
                     /score="218.8"
                     /specificity="PKS signature: (unknown)"
                     /specificity="Minowa: mal"
                     /specificity="consensus: mal"
                     /tool="antismash"
                     /translation="LFPGQDAQFPGMAQTLYRDEPLFRAEVDACAAQLRERHGIDLMPR
                     LFSPGGDADPAYATDPLPLFVLEYSLVQVWLALGVRPQAMLGYSLGEYACAVLAGVMSR
                     DDALALAVAGSRLLSLVKPGALLAVSLPESELRPLLEPGLEIAMVMAPRQCVVGGAAEA
                     VQALERRLVAQGAACLSSQLGLPFHTAHMDAFLAPYREEVRKVKLAPPRLPYVSCVSGD
                     WITAAEATDPEHYLQLGRQAVHLAQGLEKVFTLPAVQAGGLLLEVGPSQTITSLVYLQA
                     QRP"
     CDS_motif       complement(5912..5983)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg173_3_0006"
                     /evalue="1.30E+01"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg173_3"
                     /protein_end="721"
                     /protein_start="697"
                     /score="-1.4"
                     /tool="antismash"
                     /translation="VVGGAAEAVQALERRLVAQGAACLS"
     CDS_motif       complement(6098..6214)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg173_3_0005"
                     /evalue="2.70E-15"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ctg173_3"
                     /protein_end="659"
                     /protein_start="620"
                     /score="48.4"
                     /tool="antismash"
                     /translation="GVRPQAMLGYSLGEYACAVLAGVMSRDDALALAVAGSRLL"
     CDS_motif       complement(6398..6454)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg173_3_0004"
                     /evalue="1.60E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="ctg173_3"
                     /protein_end="559"
                     /protein_start="540"
                     /score="17.3"
                     /tool="antismash"
                     /translation="VFLFPGQDAQFPGMAQTLYR"
     misc_feature    complement(6728..6730)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        complement(6737..8041)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg173_3_PKS_KS.1"
                     /evalue="5.50E-149"
                     /label="ctg173_3_PKS_KS.1"
                     /locus_tag="ctg173_3"
                     /protein_end="446"
                     /protein_start="11"
                     /score="488.4"
                     /tool="antismash"
                     /translation="VAIVGMALRVPGATNLEQFWDKLKHGVESTTFFSDAELRAVGVSE
                     AELADPDYVKACGKLEGAALFDAAFFDLTPREAEILDPQHRQLLECGWEALEHAGYAPG
                     SAAMQTVQESGRIGVFAGVGLNGYLIHQLVNRHDLIETLGGWQITLGNDKDFAATRLAY
                     KLDLRGPAANVSTACSTSLVAVGMGCQSLLAYQCDMILAGGCSIHLPQDRGYRYHSGGT
                     LSPDGKCRAFDAQAQGTFDANGAAVLVLKRLEDARRDGDTVHAVIRGCAINNDGAGKVG
                     YTAPSVEGQAAVIREAQEMAAVDATTIGYVETHGTGTDLGDLVEVAALTEAFRHSGAGV
                     GWCGIGSLKSNLGHLDTAAGAASLIKTVLGLQHDQIPPTLHFTAPNPKLELATSPFYVN
                     AALRDWPRLGGAPRRAGVSSFGIGGTNAHVVVEEAPP"
     CDS_motif       complement(7004..7036)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg173_3_0003"
                     /evalue="8.00E+01"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="ctg173_3"
                     /protein_end="357"
                     /protein_start="346"
                     /score="-2.8"
                     /tool="antismash"
                     /translation="SGAGVGWCGIGS"
     CDS_motif       complement(7067..7114)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg173_3_0002"
                     /evalue="1.60E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="ctg173_3"
                     /protein_end="336"
                     /protein_start="320"
                     /score="11.0"
                     /tool="antismash"
                     /translation="YVETHGTGTDLGDLVEV"
     CDS_motif       complement(7490..7537)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg173_3_0001"
                     /evalue="3.10E-04"
                     /label="PKSI-KS_m3"
                     /locus_tag="ctg173_3"
                     /protein_end="195"
                     /protein_start="179"
                     /score="13.3"
                     /tool="antismash"
                     /translation="GPAANVSTACSTSLVAV"
     CDS             complement(8067..8633)
                     /NRPS_PKS="Domain: PCP (85-153). E-value: 1.7e-22. Score:
                     71.2. Matches aSDomain: nrpspksdomains_ctg173_4_PCP.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg173_4"
                     /sec_met_domain="PP-binding (E-value: 2.4e-15, bitscore:
                     45.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="QRSTQDQRLIAYVSPMAGATLEEGALRTALANELPLHMLPARIVV
                     LDRLPINSNGKLDRAALPAPTETTEAVEDSVSPASTFTVAEQRIAAVWRELLEIARVGR
                     DDNFFEIGGHSLLVLPLRERLQALFGKPLSPADIFRYPSVAAQARFLAAADEAANNGQA
                     HLDDAKDVAQRRRDALKQMKDRKRV"
     aSDomain        complement(8175..8378)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg173_4_PCP.1"
                     /evalue="1.70E-22"
                     /label="ctg173_4_PCP.1"
                     /locus_tag="ctg173_4"
                     /protein_end="153"
                     /protein_start="85"
                     /score="71.2"
                     /tool="antismash"
                     /translation="EQRIAAVWRELLEIARVGRDDNFFEIGGHSLLVLPLRERLQALFG
                     KPLSPADIFRYPSVAAQARFLAAA"
     aSModule        8175..8378
                     /domains="nrpspksdomains_ctg173_4_PCP.1"
                     /incomplete
                     /locus_tags="ctg173_4"
                     /tool="antismash"
                     /type="unknown"
ORIGIN
        1 gagtcggaca tcgagggttg ctaattcagt aagcagtgtt tgagcagagt gcattggcct
       61 gcagttcagg aaatttgtcg tgagttacga aagagattcg gttcagctac gcgataacga
      121 ttgagtccat aaactgctgt aaatcgggag gcaggtagcc accgcttcga atcggtaaat
      181 tgacgttgtc gagacgttga tcaaccgaag aaggagaagc gatggctgca atcgatgtta
      241 gcgcaagcaa ggagttgttg cccggtttgc tgggcagcca agacggactg gcgaaactgg
      301 tggaggccgt actgaaccag atcctggagg cgcaggtcac ggaaacgttg ggcgcggagc
      361 gacacgagcg cagcgacgac cgactgggct atcgcaatgg gcatcgaccg cgcacgcttt
      421 acacgcgggt ggggccgatc acgctgctgg tgccgcagac gcgggatggc agcttctcga
      481 cagacatctt caagcgctac cagcggagcg aacaggcctt tgtgctggcg ctgatggaaa
      541 tggtcgtgca aggcgtctcg acgcgcaagg tgtcgacgat caccgaggag ctgtgcgggg
      601 cgagtttctc caagtcgacg gtcagcagtt tgtgttcagg actcgatgtt cgcgtccggg
      661 cattcaacga acgtcgactg gaaggcgagt atccgttcgt gctggtcgat gcgatgttca
      721 tccagagtcg gcaggaagat cgcgtgctga tgcgcacggt gctgatcgtc agcggggtgc
      781 gtagcgacgg catgcgcgag attctcggcg tgaagatcgg cgacagcgag agcttcgcca
      841 cttgggacga gacattccgc tggctcagag ggcgaggact gaagggcgtg gccttcgtca
      901 tctcggatca gcatggtggt ctgcgggagg ccgttgccaa gcactttcac gacgcaacct
      961 ggcagcgctg ccaggttcat ctgatgcgca acatcctcgg cagttgcggg tcgaagatcc
     1021 gcgccgaggt gacggtggca gccaaattgg tctttcaggc ggccgatctg ccggaggcac
     1081 ggcgccggtt gacggaattc agcgagcgct ttgccaagac agcccccaag gcggttgcct
     1141 gcctggaagc cgggttcgag gatgccatgg cggtcatggc attgccggag aagtatcgca
     1201 agcggctacg gacaaccaac atgcaggagc ggctcaacga ggaaatccgc cgccgcgagc
     1261 gtgtcatccg catcttcccg aacgacgaat cggcgctgcg cctgatcgga gctttgctgg
     1321 ccgagcagaa cgagacctgg ctggaaagaa agtatctgga catgcaggag tatcacgaat
     1381 gggcggcttc ctgcgccgcc gcccgagagg gcaacaacgt tgttgccctc tcgggctgaa
     1441 acccaatcgt cattgaccgg ctcggagcag atttacagca aatttcggac ttgactgcga
     1501 taacgctgac gaactgctgg ccttcctgga cagcggctgt attgtggaac gcgcaacata
     1561 tttcggccac atcgcggttc ccagcgcagc gccaatgccg aacatatcca ataacaatgc
     1621 ggctggcaaa cccatgccga aaaacagtac accggccgca cctgctgcgc cgggcaccag
     1681 ggtggcgtag taaccccgct gccgatagcg ctccatttca gcggcaagat caaacagcac
     1741 ctccaggcgg tcgaggttct gctccatgag aatgatgccg gcggtatcga gcgcgacatt
     1801 ggcggaacca ctcagggaaa taccgacggt ggcggtcttg agggcgactg tgtcgttgat
     1861 gccatcgccg acaaaacaaa tagagcggcc ctgctcgcgc aattgcctga caatggcagc
     1921 cttttcatcg ggcagcacac cggcatggca atcctcgata ccgagtgctc gggcaatccc
     1981 ccgggtcggg gcctccgcat cgccggaaac gatggcgagt ttcagcccac gcgttttgag
     2041 tcgcttgacc acggcaaatg cctcggggcg tagcgtgctg tggatttcga tgacccccac
     2101 cagcagtgca tccgcagcga caaacaacaa cgaacaaccg cgttgctcgc tatgcttctg
     2161 cagcgtcgcc agtccttccg gatcggccac atgaatacct tccttgtgca tgaaacggcg
     2221 actgccgaga caaacattgc gcttcccgag cacaaccttc acgccatagc caatttcgta
     2281 acgcgcatcg tccagttcag gcaagctcag gccccgctct gtcgccgcca gcaccacagc
     2341 ccgcgccacc ggatgggttt gctgtcggcc ggctgctgcc gccagacaaa ggacggcatc
     2401 tgcatcgagg tcacctaagc aatgaatctc gccaatgtgc ggctgttcga gcgtcagggt
     2461 accggtttta tcgaagacta cggtatcgat accgctcagc agttcgaggc tgcggccatc
     2521 cttgaccaga atgccctggc gggcgctcag atcgagataa ttaagcatgg tcaggggcgt
     2581 ggtggcacgg ttgacctcgg tcagattgca gccgatcagc gccacgccat gcaccggacc
     2641 gagcaacagc gcggtggcgc cgcctgcagc cagggttggc cccgccaggc ggtcacaaac
     2701 ggccccggcc ttttgctcga cggcggcggt gtaatcagcc gtgtcatcca gaatgcgctc
     2761 gatatgcgcc accgtcgtct gctcgcccgc tttttcgaca cgcacatgca gcttgccggc
     2821 gaccacggtg gttgatgcca acacaatatc gccggggatc ttatcgacca cgtgcgactc
     2881 ccctgtcagc gtgcgctggt cgacgctggc catgccttgc acgaccgtgc catcgatcgg
     2941 caccaactcc cccgcacgca gcacaatcac atcgcccgcg cgcaacgact cgaatggcac
     3001 gccgacttcg ctatccgcat acgccagcca gacctggcgc gggctggccc cgagaatgcg
     3061 cgccacgcgg ggtcccgagc cggcctgggt cttgatcatc agtttgtaac tgagaaagaa
     3121 gccgagcgaa gatcctgcta ccagcaagta gtagccactg cctaaactgg ccaatgtcag
     3181 gacggcgccg accatgctcg aacgtggccg gcgctccacc agcgcgccga ttgttgccga
     3241 cttgtacaag ggcagtgcca gataagtcag cagagatacc gccaccaggc ccgccggtgg
     3301 aaaaaccagc gccagggccg aagtgcccag cgccacgccg gcaacctgca gataatggtc
     3361 ggccttctcc gtatccagca tctggtaggc cgcagaggtc gccaccggca ccacagctga
     3421 ctgcccagca gcaaccggaa ccgctgccgc cgacaccgcc gctgcaatgt ccggcttgac
     3481 cccttggaca gcagcagagc gctcccgcat cgcattgatg cctgcataca ctgccccacc
     3541 gaggatgatc aggatatcca gcatctttac atgctagttg tgcttggcga aatcacaact
     3601 ccccctcctc ccggtcctcc tcctgccctg tcccgatcgc tgcatcgacc agcgcggcaa
     3661 tggcggtgat ggtggggcgc tcgaagagca ccgccaagga gagttcgacg cgaaagcgct
     3721 tgcggatctg cgccagcagt tgggtcagta gcagcgagtt gccgccgagt tcgaagaagc
     3781 tgtcttcggc accgacgccg tcgatgccga gcagttgttc ccacagcgtg gcgatggtct
     3841 gctgcgtggc accggtgggg gcgacgtaag cgcccataag ggacgggcgg gcgtggcgcg
     3901 cggcggcggg aacgacggac ggcgcggctt ccatctgtac ccactggcgc aggcgctggc
     3961 cgaggtcgga ggtggagagg gcgatgcgtt cggggttcgg catggcgagg atgcgctcga
     4021 aggcggcggc gccctcttcc gccgtcaggc cgagttcttc gacggcggcc ccagcgcctg
     4081 cggctcctgt tagacccgtg gttggactct catcgaagcg ccagccttcc cagttcaccg
     4141 tgagccaacg aaccggatgc gttaggttgt gcgcggcggc gcaggcgtcg agcgcggcgt
     4201 tggcggcggc gtaggcggcg aagccgaggc cgccgaggat gggcgaaagc gaggagcaga
     4261 gcaggcagaa gtcgagcggc ctatcgccca gcacttgttc gagcacacgc gcgccgccga
     4321 gtttcggtcc gatctggcgc gcgcagaatt cgggcgtgct ttcggcgacg gtggcgaagg
     4381 atgcctggcc gacgagtcct gccgcgtgga tgacgccatt gaccggcccc catccgcgct
     4441 cggtgacggc gagcagcgta gccatggcat cggcatcagt gacgtcggcg gcgacaatgc
     4501 gcacctcgac gcccagcttg gcaatctcgg cgcatgcggc acgccgcgcg gcctgcagcg
     4561 catcgtcgcg tgagggatcg tttggcaggc cggcgcggcc ggtgagcagc aggcgcgcac
     4621 ccggcgcgcg ctgggcgatg cgcctggcca gcgcgaggcc gatgttgccg aggccgccgg
     4681 tgatgaggta gacgccgccg gggcgcagcg gcagggctgc gctttcgctt ggcaggtgcg
     4741 ggacgaagct ttcgacccag cgttgcgtgc cgcgcaacgc gacggcgctt tcatctccgg
     4801 ccgtcagttc ggccagcagc gcgtcgagca ggcgcgcgcg gcgccagggc tggtcaggaa
     4861 tctcgatgtc gatggcgcgg cagcgcaggt tgggaatctc ctgcggcagc acgcgcagcg
     4921 gccccatcgc cgcagcggcg gccggcgcgg gcacgctggc gccgagcgcg cagaggcgcg
     4981 gggcgacgag gtcgatgcgc agggcctcgg caaaccagcg cgcgccgacg gcgcggccga
     5041 gcgcgaggag ggaatggaag ccggcgtcga gccgcgcggc atccgtgtcg gcgcaatcga
     5101 acaggccgag ctggacgatg cgcgccgggc ggcggccggc ggcgatgcgt gcatctagca
     5161 gcgcggccca gtcggtgggc agcgcggcga gctgttcgac gctggcgccg gcggcgcgca
     5221 ggcgcgtggc gagttccacc gcgatctcgc taccgccgac gagcagccat tctcctgttg
     5281 catcgcccgc agccagcgca ggccgctcct gccagagcgg tgcatggaac cactgctcct
     5341 gattcgtcag cttgccgacc gacggcggag gcaaggtggc ggcttgcggt gccgcctcga
     5401 cccaatagcg ctgatgctcg aaagcatagg tcggcagcgg cacgcggcgg cgcgtttcat
     5461 gggcgtagag cgcactccag cggatgtcga cgccggcgac ccacagtttg gccagtgccg
     5521 tggggaaagc cgactcggcg gtttcggcgc tctggaagcg cggatcgcaa agtgtggaca
     5581 gggcggcgag ttcaggcgga cgctgcgctt gcaggtagac aaggctggtg atggtctggc
     5641 tagggccgac ttcgagcagc aggccgccgg cctgcacggc gggcaacgta aagacttttt
     5701 ccaagccctg tgccagatgc acggcctggc ggccaagctg caggtagtgt tcggggtcgg
     5761 tagcttcggc ggcggtgatc cagtcaccgc tgacgcagga gacgtagggt aggcgcggcg
     5821 gggcgagttt caccttgcgc acttcctcgc ggtagggcgc gaggaaggcg tccatgtgcg
     5881 cggtgtggaa gggcaggcca agctggctgg agaggcaagc ggcaccctgg gcgacaaggc
     5941 ggcgctcgag cgcctgcacg gcctcagctg caccgccgac cacgcactgg cgcggtgcca
     6001 tgaccatggc gatttccagc cccggttcca acagcggacg cagctcgctc tcgggcagcg
     6061 agacggcgag tagcgcgccg ggcttgacca gggacaacag ccgcgaaccg gccaccgcga
     6121 gcgccagcgc gtcgtcacgg ctcatcacgc cggcgagcac ggcgcaggcg tattcgccaa
     6181 ggctgtagcc gagcatggcc tgcggccgca cgccaagcgc cagccagacc tggacgagcg
     6241 aatactccag aacgaagagc ggcagcggat cggtggcgta ggccggatcg gcgtcgccgc
     6301 cgggcgagaa caggcgcggc atgaggtcga taccgtggcg ttcgcgcagc tgggcggcac
     6361 aggcgtcgac ctcggcacgg aacagcggct cgtcgcggta gagcgtctgc gccatgccgg
     6421 ggaattgggc atcctggccg gggaagagga aaacgacggc gggcgcgtgc tcgccagcct
     6481 ggccggagaa cacgcgcggg gcgcgctccg ctgcgagggc ctgcgcagcc tcggcggcgc
     6541 tgcgcgccac cacggcgcgg cgccgggcga agggcgcgcg gccagtctgc aggctgtagg
     6601 tgatgtcggc aaaagcatcc gtactttgga gcagatgcgc ggccaggcgt tgctcgcccg
     6661 cttccagcgc gaccgcaccg cgcgcggaga gcggcagcag ctgccagggc cggccggggg
     6721 agctggctaa gaccggcggc gcttcctcga cgacgacgtg ggcattggtg ccgccgatgc
     6781 cgaaggagct gacgccggcg cggcgcggcg caccaccaag gcgcggccag tcgcgcaggg
     6841 cggcgttgac gtagaagggg ctggtagcaa gttcgagctt cgggttcggc gcggtgaagt
     6901 gcagcgtcgg cggaatctgg tcatgctgca gcccgagcac ggtcttgatc aggctggccg
     6961 caccagcggc agtgtcgagg tggccgaggt tgcttttgag cgagccgatg ccgcaccacc
     7021 ccacccccgc gccggaatgg cggaatgcct cggtgagcgc ggcgacttcg acgaggtcgc
     7081 cgaggtcggt gccagtgccg tgggtctcga cgtagccgat ggtggtggcg tccactgccg
     7141 ccatctcctg cgcctcgcgg atcacggcgg cctggccttc gacgctgggt gcggtgtagc
     7201 cgaccttgcc ggcgccgtcg ttgttgatgg cgcagccgcg gatcacggca tgcacggtgt
     7261 cgccgtcgcg ccgcgcgtct tcaagccgct tgagtaccag cacggcggcg ccgttggcgt
     7321 cgaaggtgcc ctgggcctgc gcgtcgaagg cgcggcactt gccgtcgggc gaaagcgtgc
     7381 caccgctgtg gtagcggtag ccgcggtcct gcggcaggtg gatggagcag ccgccggcga
     7441 ggatcatgtc gcactggtag gcgagcaggc tctggcagcc catgccgacg gccaccagcg
     7501 aggtcgagca ggcggtgctg acgttggccg ccgggccgcg caggtcgagc ttgtaggcca
     7561 ggcgcgtggc ggcgaagtcc ttgtcgttgc cgagcgtgat ctgccagccg cccagcgtct
     7621 cgatcaggtc atggcgattg acgagctggt ggatcaggta gccgttgagg ccgacgccgg
     7681 cgaagacgcc gatgcgcccg ctctcctgta ctgtctgcat cgccgcgctg ccgggcgcgt
     7741 agccggcgtg ttcgagcgcc tcccagccgc attcgagcag ctggcggtgc tgcgggtcga
     7801 ggatctcggc ctcgcgcggc gtgaggtcga agaaggcggc gtcgaacagc gcggcgcctt
     7861 ccagcttgcc gcacgctttc acataatcgg gatcggcgag ttcggcttcg ctaacgccaa
     7921 cggcgcgcag ctcggcatcg ctgaagaagg tggtcgattc gacgccgtgc ttcagcttgt
     7981 cccagaactg ttcgaggttc gtcgcgccgg gcacgcgcag ggccatgccg acgatggcca
     8041 caagaccaaa gtcatcgtga tcgtgttcag acacgcttgc gatccttcat ctgcttgagc
     8101 gcatcgcggc ggcgctgggc gacatctttc gcgtcgtcga gatgggcctg gccgttgttg
     8161 gccgcctcgt ccgctgcggc gaggaaacgc gcctgcgcag cgacgctggg gtagcggaag
     8221 atgtcggccg gcgacagcgg cttgccgaac aacgcctgca ggcgttcgcg cagcggcagc
     8281 accagcagcg aatggccgcc gatctcgaag aagttgtcgt cgcggccgac gcgcgcgatc
     8341 tccagcagct cgcgccagac ggcggcgatg cgctgttcgg cgaccgtaaa agtcgacgcc
     8401 ggcgacacgc tgtcttcaac cgcctccgtc gtttcggtcg gtgccggcag cgcggcgcgg
     8461 tcgagcttgc cgttgctgtt gatgggcagg cggtcgagca cgacgatgcg cgccggcagc
     8521 atgtgcagcg gcagctcatt ggccagcgcg gtacgcaggg cgccctcctc caatgtcgcg
     8581 cccgccatcg gcgaaacgta ggcaatcagc cgctggtcct gcgtgctgcg ctgc
//
