3300018875_4 - 4 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

c00016_3300018.. (original name was: 3300018875.a:Ga0193608_1000103)

Region	Type	From	To	Most similar known cluster		Similarity
Region 16.1	NRPS	34,728	78,498

c00028_3300018.. (original name was: 3300018875.a:Ga0193608_1000021)

Region	Type	From	To	Most similar known cluster		Similarity
Region 28.1	siderophore	214,005	231,566

c00032_3300018.. (original name was: 3300018875.a:Ga0193608_1000020)

Region	Type	From	To	Most similar known cluster		Similarity
Region 32.1	T3PKS	53,340	94,410

c00036_3300018.. (original name was: 3300018875.a:Ga0193608_1000033)

Region	Type	From	To	Most similar known cluster		Similarity
Region 36.1	T1PKS,NRPS	1	83,940

Region	Type	From	To	Similarity
Region 16.1	NRPS	34,728	78,498
Region 28.1	siderophore	214,005	231,566
Region 32.1	T3PKS	53,340	94,410
Region 36.1	T1PKS,NRPS	1	83,940

No secondary metabolite regions were found in these records:: c00001_3300018.. (original name was: 3300018875.a:Ga0193608_1000340); c00002_3300018.. (original name was: 3300018875.a:Ga0193608_1000119); c00003_3300018.. (original name was: 3300018875.a:Ga0193608_1000063); c00004_3300018.. (original name was: 3300018875.a:Ga0193608_1000023); c00005_3300018.. (original name was: 3300018875.a:Ga0193608_1000003); c00006_3300018.. (original name was: 3300018875.a:Ga0193608_1000288); c00007_3300018.. (original name was: 3300018875.a:Ga0193608_1000082); c00008_3300018.. (original name was: 3300018875.a:Ga0193608_1000212); c00009_3300018.. (original name was: 3300018875.a:Ga0193608_1000091); c00010_3300018.. (original name was: 3300018875.a:Ga0193608_1000128); c00011_3300018.. (original name was: 3300018875.a:Ga0193608_1000898); c00012_3300018.. (original name was: 3300018875.a:Ga0193608_1000195); c00013_3300018.. (original name was: 3300018875.a:Ga0193608_1000468); c00014_3300018.. (original name was: 3300018875.a:Ga0193608_1000052); c00015_3300018.. (original name was: 3300018875.a:Ga0193608_1000038); c00017_3300018.. (original name was: 3300018875.a:Ga0193608_1000047); c00018_3300018.. (original name was: 3300018875.a:Ga0193608_1000125); c00019_3300018.. (original name was: 3300018875.a:Ga0193608_1000018); c00020_3300018.. (original name was: 3300018875.a:Ga0193608_1000127); c00021_3300018.. (original name was: 3300018875.a:Ga0193608_1000027); c00022_3300018.. (original name was: 3300018875.a:Ga0193608_1000146); c00023_3300018.. (original name was: 3300018875.a:Ga0193608_1000155); c00024_3300018.. (original name was: 3300018875.a:Ga0193608_1000594); c00025_3300018.. (original name was: 3300018875.a:Ga0193608_1000270); c00026_3300018.. (original name was: 3300018875.a:Ga0193608_1000036); c00027_3300018.. (original name was: 3300018875.a:Ga0193608_1000012); c00029_3300018.. (original name was: 3300018875.a:Ga0193608_1000685); c00030_3300018.. (original name was: 3300018875.a:Ga0193608_1003192); c00031_3300018.. (original name was: 3300018875.a:Ga0193608_1000044); c00033_3300018.. (original name was: 3300018875.a:Ga0193608_1000655); c00034_3300018.. (original name was: 3300018875.a:Ga0193608_1000094); c00035_3300018.. (original name was: 3300018875.a:Ga0193608_1002777); c00037_3300018.. (original name was: 3300018875.a:Ga0193608_1000297); c00038_3300018.. (original name was: 3300018875.a:Ga0193608_1000025); c00039_3300018.. (original name was: 3300018875.a:Ga0193608_1000197); c00040_3300018.. (original name was: 3300018875.a:Ga0193608_1000434)

Compact view

c00016_3300018.. - Region 1 - NRPS

Download region GenBank file

Location: 34,728 - 78,498 nt. (total: 43,771 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 34727 - 78498:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (phe)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg16_48

Search NORINE for peptide: strict or relaxed

AMP-binding (256..664): phe

NRPSPredictor2: phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: phe, trp
Single AA prediction:: phe

Stachelhaus prediction details:

Stachelhaus sequence:: DAFTaAAVCK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 90% (moderate)

c00028_3300018.. - Region 1 - siderophore

Download region GenBank file

Location: 214,005 - 231,566 nt. (total: 17,562 nt) Show pHMM detection rules used

siderophore: IucA_IucC

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

c00032_3300018.. - Region 1 - T3PKS

Download region GenBank file

Location: 53,340 - 94,410 nt. (total: 41,071 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

c00036_3300018.. - Region 1 - NRPS,T1PKS

Download region GenBank file

Location: 1 - 83,940 nt. (total: 83,940 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 83940:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-X) + (pro - phe - D-phe) + (asn - tyr - leu - val - orn - leu)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 0 - 36216:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-X) + (pro - phe - D-phe)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 10253 - 83940:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-X) + (pro - phe - D-phe) + (asn - tyr - leu - val - orn - leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg36_10

PKS_AT (1071..1361): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 54.2%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 45.8
Malonyl-CoA: 42.5
Methoxymalonyl-CoA: 41.2
Isobutyryl-CoA: 26.3
inactive: 20.2
Propionyl-CoA: 14.6
Ethylmalonyl-CoA: 11.7
3-Methylbutyryl-CoA: 9.0
CHC-CoA: 8.9
2-Methylbutyryl-CoA: 8.6
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0

ctg36_19

Search NORINE for peptide: strict or relaxed

AMP-binding (37..430): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: tyr, bht
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAsTIAAICK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 90% (moderate)

ctg36_20

Search NORINE for peptide: strict or relaxed

AMP-binding (473..871): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFIAHVVK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 100% (strong)

AMP-binding (1513..1903): phe

NRPSPredictor2: phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: phe, trp
Single AA prediction:: phe

Stachelhaus prediction details:

Stachelhaus sequence:: DAWTIAGVaK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 90% (moderate)

AMP-binding (2547..2936): phe

NRPSPredictor2: phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: phe, trp
Single AA prediction:: phe

Stachelhaus prediction details:

Stachelhaus sequence:: DAWTIAAICK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 100% (strong)

ctg36_21

Search NORINE for peptide: strict or relaxed

AMP-binding (472..868): asn

NRPSPredictor2: asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKVGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 100% (strong)

AMP-binding (1510..1903): tyr

NRPSPredictor2: tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: N/A
Single AA prediction:: tyr

Stachelhaus prediction details:

Stachelhaus sequence:: DAeTTGEVVK
Nearest Stachelhaus code:: tyr
Stachelhaus code match:: 90% (moderate)

AMP-binding (2545..2940): leu

NRPSPredictor2: leu

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DGAYTGEVVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

AMP-binding (3583..3979): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAFWIGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 100% (strong)

AMP-binding (4621..5023): orn

NRPSPredictor2: orn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: orn, lys, arg
Small clusters prediction:: orn, horn
Single AA prediction:: orn

Stachelhaus prediction details:

Stachelhaus sequence:: DVGEIGSIDK
Nearest Stachelhaus code:: orn
Stachelhaus code match:: 100% (strong)

AMP-binding (5667..6061): leu

NRPSPredictor2: leu

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DGAYTGEVVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)