LOCUS       c00378_3300018..        8010 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300018915.a:Ga0193591_1001858.
ACCESSION   c00378_3300018..
VERSION     c00378_3300018..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 09:26:04
            Original ID  :: 3300018915.a:Ga0193591_1001858
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8010
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..246
                     /locus_tag="ctg378_1"
                     /transl_table=11
                     /translation="EAGSDLVRRFNPREVYVYAMGQEPWLKHIMSLVYTEASNPIIASN
                     QLIAECRSRNIVAERLFGEKEIVYDSQPEYAAAGRA"
     protocluster    1..8010
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[296:6680](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      297..6680
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..8010
                     /SMILES="CCC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..8010
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     CDS             297..6680
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (4-430). E-value:
                     1.2e-180. Score: 592.6. Matches aSDomain:
                     nrpspksdomains_ctg378_2_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (539-835). E-value: 1.6e-107.
                     Score: 351.0. Matches aSDomain:
                     nrpspksdomains_ctg378_2_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH2 (921-1132). E-value: 2e-30.
                     Score: 97.7. Matches aSDomain:
                     nrpspksdomains_ctg378_2_PKS_DH2.1"
                     /NRPS_PKS="Domain: PKS_ER (1435-1738). E-value: 1.5e-78.
                     Score: 255.8. Matches aSDomain:
                     nrpspksdomains_ctg378_2_PKS_ER.1"
                     /NRPS_PKS="Domain: PKS_KR (1762-1940). E-value: 1.5e-66.
                     Score: 215.5. Matches aSDomain:
                     nrpspksdomains_ctg378_2_PKS_KR.1"
                     /NRPS_PKS="Domain: PP-binding (2049-2110). E-value:
                     3.9e-11. Score: 35.1. Matches aSDomain:
                     nrpspksdomains_ctg378_2_PP-binding.1"
                     /NRPS_PKS="type: PKS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 114.2; E-value:
                     1e-34)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg378_2"
                     /sec_met_domain="PP-binding (E-value: 2.3e-12, bitscore:
                     35.1, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 7.2e-182, bitscore:
                     592.6, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 9.3e-109, bitscore:
                     351.0, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.3e-64, bitscore:
                     205.1, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAPIAIIGAGCRFPGGGDSARKFWDVLINGTDAIVDVPADRWDV
                     RRFYSDDDQKPGKIYTTQGGFLREKMDQFDALFFGISPREAEVMDPQQRLLLETSYEAV
                     EDAGLQLDALRGSNTGVFVGGFTFDNCLLQLGKDNRSLINSSTATGVMLTMLSNRLSYW
                     YDFKGPSITIDTACSSSLVATHYAAQSIWRGECDQAMVGGVNAIFKPEKTITMSAGRFL
                     SKHGRCKTFDADAAGYVRGEGAGIVILKPYEQALADGDKIYALIRATGVNQDGRTNGIT
                     VPNGAAQQQLMRKVYRAAGIQPRDIHYVEAHGTGTPVGDPIEFGALNEVLSEGRAAGDT
                     CLVGSVKTNIGHLEAGAGVAGLIKAALCLQHKQVPPNLHFQTPNPRLNYEQSVLRVPTR
                     VEALPPGGEALAAVNSFGYGGTNAHVLLQEYAPAPGSQPAPGNPEEPLAGPFVLPVSAR
                     DRTALKKLAHAYRAFLEANPGRLADFVYTAALRRSYHNHRLAVVADSGKDLLDKLAAFE
                     QEVFHKGVVTHSVNERPPKIVFVCTGMGPQWWKMGRTLLEKEPVFRRSLEKCDAVFRSI
                     ASWSILEELKKDEERSRMKETQIAQPANFIIQVALAELLGHYGVTPGAVVGHSVGEVAA
                     AYLAGALSLEDAMLVSYHRSRLQQTTAGQGKMMAVSLPEAEMARIIASTENVAIAAVNS
                     PNSVTLAGDEDALWQLADSLEWKGVFSRMLEVEVPYHSPLMDPIREDLLLALEGIRPGA
                     ARLDLYSTVTGAQIQGDGLGPAYWWANVRQPVRFAAVIETLLTDGYDVFVEIGPHPVLK
                     TSMAECLNAHKKAGDLVQTLNRKEPEQFQFYAALATLHALGCPLNWRQLTGSGAQIDIP
                     GYPWQKSRHWLESPASQADRLGNHANVFLATRVPAPQPAYEVELNPYFFPFLTHHIVQG
                     KVVFPGAGYVAAGIALLQAEAGEGAPPPFSVEDIAFHQLLAVDAQATQLLHTTLHPRLN
                     EFTVYSRYGGEPDAWQLHASGRFADGLLGSPGDPVDLAAIGNSCPERIPPEAVYARLAE
                     AKLEYGPPFRAIKEIKLGEGQLLARIEGPEMIAADAAGYVIHPVLLDACFQGMIAFDNK
                     DMVPVSIRQLHCYRSPGNQFYCHIRLTEVTDQAVTGDLTLCGDDGIPALQLLGLRCQRI
                     ARDTSAGKELLEASLYAPRWKETAGPAARETETAEKYFLFSEENAEEARRLGLELSLAG
                     KATVLVSGGAELERLSEHACQVDFASESQLTALFNQIEPSQVPVVLVYLPGAQLSGEGS
                     ASASACVAQITRLVNIVRAFARAQPARNATVCLVTGNAQVVVEGDAGDALVTAPLWGLG
                     NVVMNEYPAFRVKGIDLEQQAKDDAEAEHAQLRLLVEEITGNFQETEIALRGGKKYVKR
                     LVRKPAVAEVVVSQTLNTGEGGVVLRAGPSRHAEDLYFEQTPRQAPRTGEIELQVHQAA
                     VEPSVYLKATGKLSPGAPAAVECTGIVTRVGAQVQAFRVGDRVVATGRQGEIRSYLTTS
                     TDLVIHEPDGLKPGFALAATAYLTALYGLKDVARLKKDDKILIHHAAGSTGLAAVQYAR
                     WQGARVFATADTEEKRHYLRSLGLRHVYDSEQLQFAAQVLRDTGGYGVDVVLGALPGEG
                     LYQSLSLLAPYGTYLDVGKKDQAERMLLPPAFFSRSVTLTSLDVDRMLAERPRLGPALL
                     REVSEYFGNGCFTGVPVRRFPAGDAGEAFSQASENRLPGKVYLDMDQQPVAVRPGKKDP
                     ALVRKKATYLLTGSTDGLGLEIAKWLVTRGARHLVLVSRSGVKTEKARQAVAAMEKAGA
                     QVRVESVDVSDAEQVNALIDRVKQQMPPLAGVVHCAMVLDDGLLTDMTPDRFDRVLRPK
                     VDGALHLHRATSGAKLDHFICFSSISSLIGNPGQANYVAANAFLDAFGHYRQSLGLVGT
                     TINLGVLSEVGVVARSNNLEKILQHAGIQGFTTAEVLEGLELIMHQQPAQVGFFRVNWQ
                     TWASGNPKSREFSPFRELLEQENPQAKDSGKQDLLVEALGAMEPENRHPHLVRLLGGEL
                     ADVLRMPFDSIDASRGINLLGLDSIMVVELINAIRNNLGVAMVPMEFLTGPSVSQLAAV
                     VLHKLPLAGREEKIAAL"
     aSDomain        309..1586
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg378_2_PKS_KS.1"
                     /evalue="1.20E-180"
                     /label="ctg378_2_PKS_KS.1"
                     /locus_tag="ctg378_2"
                     /protein_end="430"
                     /protein_start="4"
                     /score="592.6"
                     /tool="antismash"
                     /translation="IAIIGAGCRFPGGGDSARKFWDVLINGTDAIVDVPADRWDVRRFY
                     SDDDQKPGKIYTTQGGFLREKMDQFDALFFGISPREAEVMDPQQRLLLETSYEAVEDAG
                     LQLDALRGSNTGVFVGGFTFDNCLLQLGKDNRSLINSSTATGVMLTMLSNRLSYWYDFK
                     GPSITIDTACSSSLVATHYAAQSIWRGECDQAMVGGVNAIFKPEKTITMSAGRFLSKHG
                     RCKTFDADAAGYVRGEGAGIVILKPYEQALADGDKIYALIRATGVNQDGRTNGITVPNG
                     AAQQQLMRKVYRAAGIQPRDIHYVEAHGTGTPVGDPIEFGALNEVLSEGRAAGDTCLVG
                     SVKTNIGHLEAGAGVAGLIKAALCLQHKQVPPNLHFQTPNPRLNYEQSVLRVPTRVEAL
                     PPGGEALAAVNSFGYGGTNAHVLLQEYA"
     aSModule        309..6626
                     /complete
                     /domains="nrpspksdomains_ctg378_2_PKS_KS.1"
                     /domains="nrpspksdomains_ctg378_2_PKS_AT.1"
                     /domains="nrpspksdomains_ctg378_2_PKS_DH2.1"
                     /domains="nrpspksdomains_ctg378_2_PKS_ER.1"
                     /domains="nrpspksdomains_ctg378_2_PKS_KR.1"
                     /domains="nrpspksdomains_ctg378_2_PP-binding.1"
                     /locus_tags="ctg378_2"
                     /monomer_pairings="mal -> redmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       798..845
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg378_2_0001"
                     /evalue="5.80E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="ctg378_2"
                     /protein_end="183"
                     /protein_start="167"
                     /score="21.3"
                     /tool="antismash"
                     /translation="GPSITIDTACSSSLVAT"
     CDS_motif       987..1025
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg378_2_0002"
                     /evalue="4.70E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="ctg378_2"
                     /protein_end="243"
                     /protein_start="230"
                     /score="13.2"
                     /tool="antismash"
                     /translation="FDADAAGYVRGEGA"
     CDS_motif       1218..1265
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg378_2_0003"
                     /evalue="1.30E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="ctg378_2"
                     /protein_end="323"
                     /protein_start="307"
                     /score="13.9"
                     /tool="antismash"
                     /translation="YVEAHGTGTPVGDPIEF"
     CDS_motif       1326..1370
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg378_2_0004"
                     /evalue="2.40E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="ctg378_2"
                     /protein_end="358"
                     /protein_start="343"
                     /score="10.6"
                     /tool="antismash"
                     /translation="GSVKTNIGHLEAGAGV"
     misc_feature    1401..1403
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS_motif       1908..1964
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg378_2_0005"
                     /evalue="8.40E-03"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="ctg378_2"
                     /protein_end="556"
                     /protein_start="537"
                     /score="9.1"
                     /tool="antismash"
                     /translation="VFVCTGMGPQWWKMGRTLLE"
     aSDomain        1914..2801
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg378_2_PKS_AT.1"
                     /evalue="1.60E-107"
                     /label="ctg378_2_PKS_AT.1"
                     /locus_tag="ctg378_2"
                     /protein_end="835"
                     /protein_start="539"
                     /score="351.0"
                     /specificity="Minowa: mal"
                     /specificity="consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /tool="antismash"
                     /translation="VCTGMGPQWWKMGRTLLEKEPVFRRSLEKCDAVFRSIASWSILEE
                     LKKDEERSRMKETQIAQPANFIIQVALAELLGHYGVTPGAVVGHSVGEVAAAYLAGALS
                     LEDAMLVSYHRSRLQQTTAGQGKMMAVSLPEAEMARIIASTENVAIAAVNSPNSVTLAG
                     DEDALWQLADSLEWKGVFSRMLEVEVPYHSPLMDPIREDLLLALEGIRPGAARLDLYST
                     VTGAQIQGDGLGPAYWWANVRQPVRFAAVIETLLTDGYDVFVEIGPHPVLKTSMAECLN
                     AHKKAGDLVQTLNRKE"
     CDS_motif       2151..2267
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg378_2_0006"
                     /evalue="7.50E-16"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ctg378_2"
                     /protein_end="657"
                     /protein_start="618"
                     /score="50.2"
                     /tool="antismash"
                     /translation="GVTPGAVVGHSVGEVAAAYLAGALSLEDAMLVSYHRSRLQ"
     CDS_motif       2610..2657
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg378_2_0007"
                     /evalue="9.30E-04"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="ctg378_2"
                     /protein_end="787"
                     /protein_start="771"
                     /score="11.8"
                     /tool="antismash"
                     /translation="LGPAYWWANVRQPVRFA"
     CDS_motif       3060..3119
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg378_2_0008"
                     /evalue="1.10E-07"
                     /label="PKSI-DH_m2"
                     /locus_tag="ctg378_2"
                     /protein_end="941"
                     /protein_start="921"
                     /score="24.4"
                     /tool="antismash"
                     /translation="FLTHHIVQGKVVFPGAGYVAA"
     aSDomain        3060..3692
                     /aSDomain="PKS_DH2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg378_2_PKS_DH2.1"
                     /evalue="2.00E-30"
                     /label="ctg378_2_PKS_DH2.1"
                     /locus_tag="ctg378_2"
                     /protein_end="1132"
                     /protein_start="921"
                     /score="97.7"
                     /tool="antismash"
                     /translation="FLTHHIVQGKVVFPGAGYVAAGIALLQAEAGEGAPPPFSVEDIAF
                     HQLLAVDAQATQLLHTTLHPRLNEFTVYSRYGGEPDAWQLHASGRFADGLLGSPGDPVD
                     LAAIGNSCPERIPPEAVYARLAEAKLEYGPPFRAIKEIKLGEGQLLARIEGPEMIAADA
                     AGYVIHPVLLDACFQGMIAFDNKDMVPVSIRQLHCYRSPGNQFYCHIRL"
     misc_feature    3909..3911
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS_motif       4155..4211
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg378_2_0009"
                     /evalue="6.60E+01"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="ctg378_2"
                     /protein_end="1305"
                     /protein_start="1286"
                     /score="-3.1"
                     /tool="antismash"
                     /translation="ASACVAQITRLVNIVRAFAR"
     aSDomain        4602..5510
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg378_2_PKS_ER.1"
                     /evalue="1.50E-78"
                     /label="ctg378_2_PKS_ER.1"
                     /locus_tag="ctg378_2"
                     /protein_end="1738"
                     /protein_start="1435"
                     /score="255.8"
                     /tool="antismash"
                     /translation="EDLYFEQTPRQAPRTGEIELQVHQAAVEPSVYLKATGKLSPGAPA
                     AVECTGIVTRVGAQVQAFRVGDRVVATGRQGEIRSYLTTSTDLVIHEPDGLKPGFALAA
                     TAYLTALYGLKDVARLKKDDKILIHHAAGSTGLAAVQYARWQGARVFATADTEEKRHYL
                     RSLGLRHVYDSEQLQFAAQVLRDTGGYGVDVVLGALPGEGLYQSLSLLAPYGTYLDVGK
                     KDQAERMLLPPAFFSRSVTLTSLDVDRMLAERPRLGPALLREVSEYFGNGCFTGVPVRR
                     FPAGDAGEAFSQASENRLPGKVY"
     CDS_motif       4740..4772
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg378_2_0010"
                     /evalue="6.90E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="ctg378_2"
                     /protein_end="1492"
                     /protein_start="1481"
                     /score="9.5"
                     /tool="antismash"
                     /translation="VECTGIVTRVGA"
     CDS_motif       4968..5030
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg378_2_0011"
                     /evalue="4.40E-08"
                     /label="PKSI-ER_m5"
                     /locus_tag="ctg378_2"
                     /protein_end="1578"
                     /protein_start="1557"
                     /score="25.5"
                     /tool="antismash"
                     /translation="DDKILIHHAAGSTGLAAVQYAR"
     CDS_motif       5040..5090
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg378_2_0012"
                     /evalue="3.10E-06"
                     /label="PKSI-ER_m6"
                     /locus_tag="ctg378_2"
                     /protein_end="1598"
                     /protein_start="1581"
                     /score="19.7"
                     /tool="antismash"
                     /translation="GARVFATADTEEKRHYLR"
     aSDomain        5583..6116
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg378_2_PKS_KR.1"
                     /evalue="1.50E-66"
                     /label="ctg378_2_PKS_KR.1"
                     /locus_tag="ctg378_2"
                     /protein_end="1940"
                     /protein_start="1762"
                     /score="215.5"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="ATYLLTGSTDGLGLEIAKWLVTRGARHLVLVSRSGVKTEKARQAV
                     AAMEKAGAQVRVESVDVSDAEQVNALIDRVKQQMPPLAGVVHCAMVLDDGLLTDMTPDR
                     FDRVLRPKVDGALHLHRATSGAKLDHFICFSSISSLIGNPGQANYVAANAFLDAFGHYR
                     QSLGLVGTTINLGVLS"
     CDS_motif       5586..5684
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg378_2_0013"
                     /evalue="5.20E-15"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg378_2"
                     /protein_end="1796"
                     /protein_start="1763"
                     /score="47.9"
                     /tool="antismash"
                     /translation="TYLLTGSTDGLGLEIAKWLVTRGARHLVLVSRSG"
     CDS_motif       5964..6074
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg378_2_0014"
                     /evalue="4.10E-23"
                     /label="PKSI-KR_m4"
                     /locus_tag="ctg378_2"
                     /protein_end="1926"
                     /protein_start="1889"
                     /score="74.0"
                     /tool="antismash"
                     /translation="LDHFICFSSISSLIGNPGQANYVAANAFLDAFGHYRQS"
     aSDomain        6444..6626
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg378_2_PP-binding.1"
                     /evalue="3.90E-11"
                     /label="ctg378_2_PP-binding.1"
                     /locus_tag="ctg378_2"
                     /protein_end="2110"
                     /protein_start="2049"
                     /score="35.1"
                     /tool="antismash"
                     /translation="ELADVLRMPFDSIDASRGINLLGLDSIMVVELINAIRNNLGVAMV
                     PMEFLTGPSVSQLAAVV"
     CDS             6721..8010
                     /NRPS_PKS="Domain: AMP-binding (13-428). E-value: 2.5e-86.
                     Score: 281.6. Matches aSDomain:
                     nrpspksdomains_ctg378_3_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     246.5; E-value: 7.1e-75)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg378_3"
                     /sec_met_domain="AMP-binding (E-value: 7e-92, bitscore:
                     295.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNTLQQRLAGSFRQHSRLTAIECADRRISYAALGEASGRIASFF
                     LRREIPAATRVGVLLNGRLDFICAITGLLRGRYVFVPLDPRLPVERLAAMTRHLDLAHV
                     LTSRESLAEIGGQTALPASVNLHYLDEMDLDETGPDEIGEEPQPAGRVLTLPDCHPDDP
                     IYVYFTSGSTGEPKGIVGRNASLLHFLEWEISTFGVGPGCKVSQFTTPGFDAALRDIFV
                     PLLAGGMVCIYREKEQEVYEQELTQWIDDHRINLIHCVPSFFRLINHPGIGAQNYPHLQ
                     YVLLAGEQLVPRHLAQWYATMGDRIQLVNLYGATETTLVKTFYRVGPPDARLNTIPVGK
                     PIHDTEIFVLDPQLRPCPPGVAGDVYIHTPYVSLGYFGDEALTRRKFLPDPFGGAAEAP
                     FYDTGDVGQLLPDGNLVLLGRKDRQVKLRGV"
     aSDomain        6760..8004
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg378_3_AMP-binding.1"
                     /evalue="2.50E-86"
                     /label="ctg378_3_AMP-binding.1"
                     /locus_tag="ctg378_3"
                     /protein_end="428"
                     /protein_start="13"
                     /score="281.6"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="RQHSRLTAIECADRRISYAALGEASGRIASFFLRREIPAATRVGV
                     LLNGRLDFICAITGLLRGRYVFVPLDPRLPVERLAAMTRHLDLAHVLTSRESLAEIGGQ
                     TALPASVNLHYLDEMDLDETGPDEIGEEPQPAGRVLTLPDCHPDDPIYVYFTSGSTGEP
                     KGIVGRNASLLHFLEWEISTFGVGPGCKVSQFTTPGFDAALRDIFVPLLAGGMVCIYRE
                     KEQEVYEQELTQWIDDHRINLIHCVPSFFRLINHPGIGAQNYPHLQYVLLAGEQLVPRH
                     LAQWYATMGDRIQLVNLYGATETTLVKTFYRVGPPDARLNTIPVGKPIHDTEIFVLDPQ
                     LRPCPPGVAGDVYIHTPYVSLGYFGDEALTRRKFLPDPFGGAAEAPFYDTGDVGQLLPD
                     GNLVLLGRKDRQVKLRG"
     aSModule        6760..8004
                     /domains="nrpspksdomains_ctg378_3_AMP-binding.1"
                     /incomplete
                     /locus_tags="ctg378_3"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       7213..7260
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg378_3_0001"
                     /evalue="1.70E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg378_3"
                     /protein_end="180"
                     /protein_start="164"
                     /score="23.6"
                     /tool="antismash"
                     /translation="YVYFTSGSTGEPKGIVG"
     CDS_motif       7792..7881
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg378_3_0002"
                     /evalue="1.30E-08"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg378_3"
                     /protein_end="387"
                     /protein_start="357"
                     /score="27.1"
                     /tool="antismash"
                     /translation="PPGVAGDVYIHTPYVSLGYFGDEALTRRKFL"
     CDS_motif       7972..8007
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg378_3_0003"
                     /evalue="9.50E-05"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg378_3"
                     /protein_end="429"
                     /protein_start="417"
                     /score="15.1"
                     /tool="antismash"
                     /translation="LGRKDRQVKLRGV"
ORIGIN
        1 gaggccggca gcgacctggt gcgccgcttc aacccccggg aggtatacgt gtacgccatg
       61 ggccaggagc cctggctcaa acacatcatg agcctggtct acaccgaagc gtccaacccg
      121 attattgcct ccaaccaact catcgccgag tgccggagcc gcaacatcgt ggccgagcgg
      181 ctcttcggtg aaaaagaaat cgtgtacgac agccagccgg agtacgcggc agccggccgg
      241 gcgtaagcaa cgtccggccc gccccttttc ccttcaccca ctcaatttcc atcattatga
      301 atgcgccaat tgccattata ggagccggat gccggtttcc gggaggggga gactctgccc
      361 gaaaattctg ggacgtcctc atcaatggta cggatgccat cgtggacgta cccgccgacc
      421 gctgggacgt gcgccgtttt tacagcgacg acgaccagaa gccggggaag atctacacca
      481 cgcagggcgg tttcctgcgg gaaaaaatgg atcagttcga cgcccttttc ttcggcatct
      541 ccccgcggga ggccgaagtg atggacccgc agcagcgcct gctgctcgaa acctcctacg
      601 aagccgtgga agacgcgggg ttgcagctcg atgcgctccg gggcagcaat acgggcgtat
      661 tcgtgggtgg gttcaccttc gacaattgcc tgttgcagtt ggggaaagac aaccggtccc
      721 tcatcaactc cagcacggca accggggtga tgctgacgat gctctccaac cggctctcgt
      781 actggtatga tttcaaagga cccagcatca ccatcgacac cgcctgctcc tcctcgctgg
      841 tggctacgca ctacgcggcc cagagcatct ggcgcgggga gtgcgaccag gccatggtgg
      901 gcggggtaaa cgccatattc aagcccgaaa aaacgattac catgagcgcc ggccggtttc
      961 tgagcaagca cggccgctgc aaaaccttcg acgccgacgc cgccgggtac gtccggggcg
     1021 agggcgccgg gatcgtgatc ctgaagcctt acgagcaggc gctggccgac ggcgacaaga
     1081 tctacgccct catccgggcc acgggggtga accaggacgg gcgaacgaac ggcattaccg
     1141 tacccaacgg cgcggcccag caacaactca tgcgcaaagt gtaccgggcc gccggcatcc
     1201 agccccggga cattcactac gtggaagccc acggcacggg cacccccgtc ggcgacccca
     1261 tcgagttcgg cgccctcaac gaagtgcttt cggaaggcag agccgccggc gacacctgcc
     1321 tggtcggctc cgtaaaaacc aacatcgggc acctggaagc gggggccggg gtggccggac
     1381 tcatcaaagc cgccctgtgc ttacagcata agcaagtacc gcccaacctg cactttcaaa
     1441 cccccaaccc ccggttgaac tacgagcaaa gcgtgctccg cgtacccacc cgggtcgaag
     1501 ccctgccccc gggtggggag gcgctggcgg cggtgaattc cttcggctac ggcggcacca
     1561 acgcccacgt gttgctccag gaatacgccc ccgcgccggg cagccaaccg gcaccgggga
     1621 acccggagga gccgctggcc ggcccgttcg tgctgcccgt atcggcccgc gacagaaccg
     1681 ccctcaaaaa gctggcgcac gcgtaccggg cgtttctgga agcgaacccg ggccgcctgg
     1741 ctgatttcgt gtacacggcg gccctgcggc gctcctacca caaccaccgg ctggccgtgg
     1801 tggccgattc gggcaaagac ctgctcgaca agctggcggc gtttgaacag gaagtgtttc
     1861 acaagggggt cgtcacgcat tcggtgaacg aacgtcctcc caaaatcgtg ttcgtctgta
     1921 ccggcatggg gccgcagtgg tggaagatgg ggcgcaccct cctggaaaaa gagcccgtgt
     1981 tccgccggag cctcgaaaag tgcgacgccg tgttccgttc cattgcgtcc tggtccatcc
     2041 tggaggagtt gaagaaagac gaggaacggt ccaggatgaa agaaacccag atcgcccaac
     2101 cggccaactt catcatccag gtggccctgg ccgaactgct cgggcactac ggcgttacgc
     2161 ctggtgcggt ggtcggccac agcgtcggcg aagtagccgc cgcctacctg gccggcgccc
     2221 tttcgctgga agacgccatg ctggtgagct atcaccggag ccggctgcag cagacgaccg
     2281 ccgggcaggg aaaaatgatg gccgtatcgc tgccggaagc cgaaatggcc cgcatcatcg
     2341 cgtccaccga aaacgttgcc atcgccgccg tcaacagccc caactcggtg accctggccg
     2401 gcgacgaaga cgccctctgg caactggccg acagcctgga atggaaaggg gtgttcagcc
     2461 ggatgctcga agtggaagtg ccctaccaca gccccctgat ggaccccatc cgcgaagacc
     2521 tgctcctggc gctggaaggc atccggcccg gggcggcccg cctggacctg tactcaaccg
     2581 tcaccggcgc gcaaatccag ggcgacggcc tcggcccggc ctactggtgg gccaacgtgc
     2641 ggcaaccggt ccggttcgcc gcggtgatcg aaaccctgct gaccgacggg tacgacgtgt
     2701 tcgtggaaat agggccgcac ccggtgctga aaacttccat ggccgaatgc ctgaacgcgc
     2761 acaagaaagc cggtgacctg gtgcaaaccc tcaaccgcaa agaacccgag cagttccagt
     2821 tttacgccgc cctggctacg ctgcacgcgc tgggttgccc gctcaactgg cggcagctca
     2881 ccggcagcgg cgcccaaatc gacattcccg gctacccctg gcagaaaagc cggcattggc
     2941 tggagagccc ggcctcgcag gccgaccggt tgggcaacca cgccaacgta ttcctggcta
     3001 cccgggtgcc ggcgccgcag ccggcctacg aagtggaact gaacccctat ttctttccct
     3061 tcctcaccca ccacatcgtg caggggaaag tcgttttccc gggggccggt tacgtggcgg
     3121 ccggcattgc cttgctgcag gcggaagcgg gggagggcgc gcccccgccc ttttccgtgg
     3181 aagacattgc gtttcaccaa ctgctcgccg tggatgccca ggccacccaa ctgctgcaca
     3241 ccaccctcca cccccggctc aacgagttta cggtgtacag ccggtacggc ggggaacccg
     3301 atgcctggca actgcacgcc agcggccggt tcgcggacgg gctgctgggc agccccggcg
     3361 acccggttga cctggcggcc atcgggaaca gttgcccgga acgcatcccg ccggaagccg
     3421 tttacgcccg gctggcggag gcgaagctgg agtatggccc tcctttccgg gccatcaaag
     3481 aaattaaact gggcgagggc caactgctgg cccgcatcga aggccccgaa atgattgcgg
     3541 ccgacgcagc ggggtacgtg atccacccgg tgctgctcga cgcttgcttc cagggaatga
     3601 tcgccttcga caacaaggac atggtgcccg tatccatccg gcaactgcac tgctaccggt
     3661 cgccgggaaa ccagttttac tgccacatcc ggctgaccga ggtcaccgac caggccgtta
     3721 ccggcgacct caccctgtgc ggggacgacg gaattccggc cctgcaattg ctggggctgc
     3781 gctgccagcg cattgcgcgg gacacttcgg ccggcaaaga gttgctggaa gcgtcgctgt
     3841 acgcgccccg ctggaaagaa accgccgggc cggccgcccg ggaaacggaa acggcggaaa
     3901 aatacttttt attctcggaa gaaaacgcgg aagaggcgcg ccggctcggc ctggaacttt
     3961 ccctcgccgg caaggctacg gtgctcgtga gcggcggcgc cgaactggaa cggctgagcg
     4021 aacacgcctg ccaggttgat ttcgccagcg aaagccagct cacggcgctc ttcaaccaga
     4081 tcgagccttc ccaggtgccc gtcgtgctgg tatacctgcc gggcgcgcaa ctcagtgggg
     4141 aaggttcggc gagtgcatcc gcctgcgtcg cgcagatcac ccgcctggtc aacatcgtcc
     4201 gggcgtttgc ccgcgcccag ccggcccgca acgccaccgt ctgcctggtg acgggcaatg
     4261 cgcaggtcgt ggtggaaggc gacgccggcg acgccctggt tacggccccg ctgtgggggt
     4321 tgggcaacgt ggtcatgaac gagtacccgg ccttccgggt aaaaggcatc gacctggagc
     4381 agcaggccaa ggacgacgcg gaagccgagc acgcgcaatt gcgcctgctg gtggaagaaa
     4441 tcacgggaaa tttccaggag acggaaatcg ccctgcgcgg cgggaaaaag tacgtaaagc
     4501 gcctggtccg aaaaccggcc gtcgccgaag tagtcgtctc ccagaccctc aacacgggcg
     4561 aaggcggcgt agtcctgcgg gccgggccgt cgaggcacgc ggaagacctg tattttgagc
     4621 aaacgccccg gcaggcgccg cgtaccggcg agatcgaatt gcaggtgcac caggcggccg
     4681 tggagccgtc agtgtacctg aaagcgacgg gcaaactgtc gcccggcgcc ccggccgccg
     4741 tggaatgcac cggcatcgtt acccgggtcg gggcgcaggt gcaggcgttc cgcgtggggg
     4801 accgcgtcgt tgccacgggc cggcaagggg agatcaggtc ttacctgacg acctccaccg
     4861 acctggtcat tcacgagccc gacgggctca agccgggttt cgcactggcg gcgacggctt
     4921 acctgacggc gctctacggg ttgaaggacg tggcccggct gaaaaaagac gacaaaatcc
     4981 tgatccacca cgcggcgggc agcaccgggc tggccgcggt ccagtacgcc cgctggcagg
     5041 gagcccgggt gtttgccacg gccgacacgg aggaaaagcg ccactacctg cggtccctgg
     5101 ggctgcggca cgtgtacgat tcggaacaat tgcaatttgc cgcccaggtg ttgcgcgata
     5161 ccggcgggta cggcgtagac gtggtgctcg gcgccctgcc gggcgaaggc ctgtaccaga
     5221 gcctgtcgct gctggcgccg tacggcacct acctggacgt gggcaaaaag gaccaggcgg
     5281 agcggatgct cctgcccccg gctttcttca gccggagcgt cacccttacg tccctcgacg
     5341 tggaccggat gctcgcggaa cggccgcgcc tcgggccggc gctgttgcgg gaggtttcgg
     5401 aatacttcgg gaacggctgt ttcacggggg tgccggtccg ccggttcccg gccggcgacg
     5461 cgggggaagc cttctcgcag gcgtcggaaa accggctgcc gggcaaggtg tacctcgaca
     5521 tggaccagca acccgtggcg gtgcggcccg gcaaaaagga ccccgccctg gtccggaaaa
     5581 aggccaccta cctgcttacc ggcagtaccg acgggctggg actcgaaatt gccaaatggc
     5641 tcgtcacccg cggcgcccgt cacctggtgc tggtgagccg gtccggcgta aaaaccgaaa
     5701 aggcccggca ggcggtggcg gccatggaga aagccggcgc ccaggtgcgg gtggagtccg
     5761 tcgacgtgag cgatgccgaa caggtaaacg ccctcatcga ccgggtgaag caacagatgc
     5821 cgcccctggc cggcgtggtg cattgcgcca tggtactcga cgacggcctg ctgaccgaca
     5881 tgacgcccga ccgtttcgac cgggtattgc gccccaaagt agacggcgcc ctgcacctgc
     5941 accgggccac cagcggggcc aagctcgacc acttcatctg tttttcttcc atctcgtcgc
     6001 tcatcggcaa tcccgggcag gccaactacg tagccgccaa tgcgttcctg gatgctttcg
     6061 gccactaccg gcaaagcctc ggcctggtcg gcacgaccat caacctgggg gtgctgtcgg
     6121 aagtaggcgt ggtggcccgc agcaacaacc tggaaaagat cctccagcac gcgggcatcc
     6181 agggattcac caccgccgaa gtactcgaag ggctggaact gatcatgcac cagcagcccg
     6241 cccaggtcgg ctttttccgg gtgaactggc aaacctgggc ttccggcaat cccaaaagcc
     6301 gggagttttc gcccttccgg gaactgctcg aacaggagaa cccgcaggcc aaagacagcg
     6361 gcaaacaaga cctgctcgtg gaggcgctcg gcgcgatgga acccgaaaac cggcacccgc
     6421 acctggtccg gctgctcggc ggcgaactgg cggacgtact ccggatgccg ttcgacagca
     6481 ttgacgccag ccggggcatc aacctgctgg gcctcgattc catcatggtg gtggaactca
     6541 tcaacgcgat cagaaacaac ctgggggtgg ccatggtgcc catggaattc ctcaccgggc
     6601 cctcggtaag ccaactggcc gccgtggtcc tccacaagct gccgcttgcc ggcagggaag
     6661 aaaaaatcgc cgccctgtag cttcaattgc ccattcaccc cttgccctaa ccaagaattc
     6721 atgaaaaata cgctccagca gcgcctggcg ggcagcttcc gccaacacag ccggcttacg
     6781 gcgattgaat gcgcggaccg ccgcatcagc tacgccgccc tcggggaagc gtccgggcgg
     6841 attgcgtctt tcttcctccg ccgggagatt cccgccgcca cgcgggtcgg ggtgctgctc
     6901 aacggccggc tggattttat ctgcgcaatc acgggcctgc tgcgggggcg gtacgtgttc
     6961 gttcccctcg acccccggct gcccgtggag cggctggccg ccatgacccg ccacctcgac
     7021 ctggcgcacg tactcaccag ccgcgagagc ctggccgaaa ttggcggcca aacggcgctg
     7081 ccggcaagcg tgaacctgca ctacctggac gagatggacc tggacgaaac cggtccggac
     7141 gagatagggg aggagcccca acctgccggc cgggtcctta cgcttcccga ctgccacccc
     7201 gacgacccca tttacgtgta ctttacctcc ggctccacgg gcgaacccaa gggcatcgtg
     7261 ggccggaatg cgagcctgct gcatttcctg gaatgggaaa taagcacttt cggggtgggg
     7321 cccggctgca aggtcagcca gttcaccacg ccggggttcg acgccgccct gcgcgacatt
     7381 ttcgtgccgc tgctggccgg gggcatggtg tgcatctacc gggaaaagga acaagaggtg
     7441 tacgagcagg aacttacgca gtggatcgac gaccaccgca tcaacctcat ccactgcgtg
     7501 cccagtttct tccggctcat caaccacccc gggatcggcg cccaaaatta cccgcacctg
     7561 caatacgtgc tgctggccgg ggagcaactg gtgccccggc acctggcgca gtggtacgcc
     7621 accatgggcg accgtatcca gctcgtgaac ctgtacgggg ccaccgaaac cacgctcgta
     7681 aaaacgtttt accgggtcgg gccgccggac gcccgcctga acaccatccc ggtgggcaag
     7741 cccatccacg acacggaaat cttcgtgctt gacccgcagc tgcggccttg tccgcccggg
     7801 gtggccggcg acgtatacat tcacacgccc tacgtgagcc tggggtattt cggggacgaa
     7861 gccctcaccc gccgcaagtt tctgcccgac ccgttcggcg gtgcggccga agccccgttc
     7921 tacgatacgg gcgacgtcgg acagctgctc cccgacggca acctggtgct gctcggccgc
     7981 aaagaccgcc aggtaaagct gcggggcgtg
//
