LOCUS       c00464_3300018..        5769 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300018915.a:Ga0193591_1003816.
ACCESSION   c00464_3300018..
VERSION     c00464_3300018..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 09:26:04
            Original ID  :: 3300018915.a:Ga0193591_1003816
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5769
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5769
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:5769]"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..5769
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..5769
                     /SMILES="NC(CO)C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5769
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             2..2107
                     /NRPS_PKS="Domain: AMP-binding (103-509). E-value: 1e-111.
                     Score: 365.1. Matches aSDomain:
                     nrpspksdomains_ctg464_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (612-681). E-value: 6.2e-17. Score:
                     53.3. Matches aSDomain: nrpspksdomains_ctg464_1_PCP.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     375.9; E-value: 4.2e-114)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg464_1"
                     /sec_met_domain="AMP-binding (E-value: 7.7e-124, bitscore:
                     400.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.4e-15, bitscore:
                     44.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="IDGLTLNQRETGHGIAKFDLELLVTEQNHALHFNLEYATDLFGRN
                     TVERFAAYFRRIAAAVIADADVRIGDVDMLPPRERQQLLLDFNNTRADYPAGATLMDLF
                     EEQVRKTPGNVAVWVQNQAITYRELSERSNRMAHYLREHQGVRCGDLVGLLLEREEEMF
                     PTIFGILKAGAAYVPLSVDHPAARIGAILAGSGLKVLVTRRQYAEAVQTEGPLAILDLD
                     AVAGRIAQLPAGPPLTRPRGSDLAYVIYTSGSTGRPKGVMIEHHSVVNRLLWMQKEYNL
                     TEEDVLMQKTPLVFDVSVWELFWWAMTGASVCVLAPGAEKEPEKVMRAVEACRVSVLHF
                     VPSMLSAFLGAAEAQGTDRLATLRHVFASGEALTPDQVQRFGRTLHAGHGTRLVNLYGP
                     TEATVDVSYHACDFRPAASVPIGKPIDNTQLYVLDPYNGVCPVGVAGELCIGGAGLARG
                     YLNDEAQTQAKFVPHPFAREGRIYRTGDLACWLPDGSVKFLGRLDHQVKIRGFRIELGE
                     IEAQLTLHPAVSDAVVLVTERAGHKYLVAYYAAAPLPAAELNGYLARHLPHYMIPGYYV
                     HLEALPLTTNGKVDRKKLPAPEAGPAAPCVPPATPVEAKLRRIWSEALAVDEDVISTDS
                     NFFEIGGHSLIATFLANQVAKEFAVGFDLQDVFTKQSIKAQAAHIELDDWIFEAQTDSD
                     ESIQVTV"
     aSDomain        311..1528
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg464_1_AMP-binding.1"
                     /evalue="1.00E-111"
                     /label="ctg464_1_AMP-binding.1"
                     /locus_tag="ctg464_1"
                     /protein_end="509"
                     /protein_start="103"
                     /score="365.1"
                     /specificity="consensus: ser"
                     /tool="antismash"
                     /translation="FEEQVRKTPGNVAVWVQNQAITYRELSERSNRMAHYLREHQGVRC
                     GDLVGLLLEREEEMFPTIFGILKAGAAYVPLSVDHPAARIGAILAGSGLKVLVTRRQYA
                     EAVQTEGPLAILDLDAVAGRIAQLPAGPPLTRPRGSDLAYVIYTSGSTGRPKGVMIEHH
                     SVVNRLLWMQKEYNLTEEDVLMQKTPLVFDVSVWELFWWAMTGASVCVLAPGAEKEPEK
                     VMRAVEACRVSVLHFVPSMLSAFLGAAEAQGTDRLATLRHVFASGEALTPDQVQRFGRT
                     LHAGHGTRLVNLYGPTEATVDVSYHACDFRPAASVPIGKPIDNTQLYVLDPYNGVCPVG
                     VAGELCIGGAGLARGYLNDEAQTQAKFVPHPFAREGRIYRTGDLACWLPDGSVKFLGRL
                     DHQVKIRG"
     aSModule        311..2044
                     /complete
                     /domains="nrpspksdomains_ctg464_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg464_1_PCP.1"
                     /locus_tags="ctg464_1"
                     /monomer_pairings="ser -> ser"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       500..538
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg464_1_0001"
                     /evalue="1.60E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg464_1"
                     /protein_end="179"
                     /protein_start="166"
                     /score="18.0"
                     /tool="antismash"
                     /translation="FGILKAGAAYVPLS"
     CDS_motif       737..796
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg464_1_0002"
                     /evalue="5.20E-12"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg464_1"
                     /protein_end="265"
                     /protein_start="245"
                     /score="37.3"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVMIEHH"
     CDS_motif       1322..1411
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg464_1_0003"
                     /evalue="1.30E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg464_1"
                     /protein_end="470"
                     /protein_start="440"
                     /score="52.6"
                     /tool="antismash"
                     /translation="PVGVAGELCIGGAGLARGYLNDEAQTQAKFV"
     CDS_motif       1493..1558
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg464_1_0004"
                     /evalue="6.00E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg464_1"
                     /protein_end="519"
                     /protein_start="497"
                     /score="40.6"
                     /tool="antismash"
                     /translation="FLGRLDHQVKIRGFRIELGEIEA"
     aSDomain        1838..2044
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg464_1_PCP.1"
                     /evalue="6.20E-17"
                     /label="ctg464_1_PCP.1"
                     /locus_tag="ctg464_1"
                     /protein_end="681"
                     /protein_start="612"
                     /score="53.3"
                     /tool="antismash"
                     /translation="EAKLRRIWSEALAVDEDVISTDSNFFEIGGHSLIATFLANQVAKE
                     FAVGFDLQDVFTKQSIKAQAAHIEL"
     CDS             2131..5769
                     /NRPS_PKS="Domain: Condensation_LCL (68-356). E-value:
                     2e-102. Score: 333.9. Matches aSDomain:
                     nrpspksdomains_ctg464_2_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (520-943). E-value:
                     6.3e-100. Score: 326.3. Matches aSDomain:
                     nrpspksdomains_ctg464_2_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1047-1117). E-value: 1.6e-21.
                     Score: 68.0. Matches aSDomain:
                     nrpspksdomains_ctg464_2_PCP.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     376.3; E-value: 3.2e-114)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg464_2"
                     /sec_met_domain="Condensation (E-value: 3.1e-84, bitscore:
                     269.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 6.1e-113, bitscore:
                     364.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 8e-17, bitscore:
                     48.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQLLKQLKEVNARITVENGDLKLSFPKGVDASALLPRVRTHKQE
                     LIEYIGKRKGSAQQTAIGPVEKREHYPLSSAQRRLYFLHEIDPASLAYNMPLVLELEGA
                     LDRGRVEKAFGELVGRHEALRTSIRKAGDEVVQVVHDHVPFALEYHAAEGASLDGIIGQ
                     FTRPFDLGQAPLMRAALVTLPAGRHALLVDMHHIVADGVSMQLLSRDFIACYNGKPPAP
                     LALQYKDYTAWQQSAAYRQQLERQRAFWLHAFAGEVSPLDLPFDRPRPPVKSFAGDSVT
                     LVMGPDATRKLRAVADKAGATMFMNLLAIFNVLLGKLSNQSDIVIGTPVSGRHHADAQD
                     IVGVFINTLALRNTVDGNLPFIDFLARVKENTRAALALQAYPYEELVEDLKIPRDAGHN
                     PLFDVMFSFENLSGGELSMQGLKVRPYDTPHRFAKFDLELIATEANDELQLIFEYSTDV
                     FTRETMERFAAYFGKAVREITANDAQPVGAIDILSDEERRTILHGFNATARDYPLHRTF
                     VDLFEEQAVLHADAIAAADAGEACPYAGLNARANQLAHTLLAGGLAPEAAVVVLCNRSV
                     KMLAAFIGILKAGGAYVPLSPEFPAARIGDMLRDCGATFLIAESSTITPGLLAQLRSRV
                     PALRVICLDHGGTMEDAAEGFVNAAAWGTAPAGNPDRRVTPGHLAYILYTSGSTGMPKG
                     VMIEHRGMLNHLLLKRDDLELTAGSVVAQNASETFDISIWQFLSPLIVGGRTVIYAKDL
                     VLQPAKLLRRVHEDRITILEVVPSYLSVLLTCLEEEQPAGIFAALKFLVVTGETLQKSL
                     VERWFRRFPAIRLVNAYGPTEASDDITHCILAEVPAGVSIPVGRPLPNLNVYVVSHHGQ
                     LCPVGVKGEIVVSGVGVGRGYLNQPEKTAHAFIEDPFAPVAGVRMYRTGDVGRWLPDGN
                     VDFLGRIDAQVKVNGHRIELGEIERTLSGHDGITEVVAVVGEKEGSRHLIAYYVSAQPV
                     PAPALRGFLSARLPGYMVPAHLVHLKELPLTTNGKVDRKKLPVPEVAAAACVAPETATE
                     RALARIWGEVLGIDAQSVSRHANFFELGGHSLKATTVAGRILKHLHVEVLLRDLFTHQE
                     LHKLSAHIDSLGRAPGAGIERAPEKEYYELSSTQRRLLFLHELNTTSLAYNMPEALHLE
                     GPLDRQRVEDTFRLLIARHESLRTRFVSLPQGTVQQVLPQADFGLEY"
     misc_feature    2140..2142
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        2335..3198
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg464_2_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="2.00E-102"
                     /label="ctg464_2_Condensation_LCL.1"
                     /locus_tag="ctg464_2"
                     /protein_end="356"
                     /protein_start="68"
                     /score="333.9"
                     /tool="antismash"
                     /translation="EHYPLSSAQRRLYFLHEIDPASLAYNMPLVLELEGALDRGRVEKA
                     FGELVGRHEALRTSIRKAGDEVVQVVHDHVPFALEYHAAEGASLDGIIGQFTRPFDLGQ
                     APLMRAALVTLPAGRHALLVDMHHIVADGVSMQLLSRDFIACYNGKPPAPLALQYKDYT
                     AWQQSAAYRQQLERQRAFWLHAFAGEVSPLDLPFDRPRPPVKSFAGDSVTLVMGPDATR
                     KLRAVADKAGATMFMNLLAIFNVLLGKLSNQSDIVIGTPVSGRHHADAQDIVGVFINTL
                     ALRNTVDG"
     aSModule        2335..5481
                     /complete
                     /domains="nrpspksdomains_ctg464_2_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg464_2_AMP-binding.1"
                     /domains="nrpspksdomains_ctg464_2_PCP.1"
                     /locus_tags="ctg464_2"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       2404..2514
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg464_2_0001"
                     /evalue="2.20E-16"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg464_2"
                     /protein_end="128"
                     /protein_start="91"
                     /score="52.2"
                     /tool="antismash"
                     /translation="AYNMPLVLELEGALDRGRVEKAFGELVGRHEALRTSIR"
     CDS_motif       2710..2775
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg464_2_0002"
                     /evalue="1.20E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg464_2"
                     /protein_end="215"
                     /protein_start="193"
                     /score="27.5"
                     /tool="antismash"
                     /translation="MHHIVADGVSMQLLSRDFIACYN"
     CDS_motif       2806..2838
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg464_2_0003"
                     /evalue="2.90E-03"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg464_2"
                     /protein_end="236"
                     /protein_start="225"
                     /score="10.4"
                     /tool="antismash"
                     /translation="QYKDYTAWQQSA"
     CDS_motif       3097..3186
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg464_2_0004"
                     /evalue="1.00E-14"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg464_2"
                     /protein_end="352"
                     /protein_start="322"
                     /score="46.8"
                     /tool="antismash"
                     /translation="DIVIGTPVSGRHHADAQDIVGVFINTLALRN"
     CDS_motif       3235..3354
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg464_2_0005"
                     /evalue="1.40E-16"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg464_2"
                     /protein_end="408"
                     /protein_start="368"
                     /score="52.8"
                     /tool="antismash"
                     /translation="KENTRAALALQAYPYEELVEDLKIPRDAGHNPLFDVMFSFE"
     misc_feature    3376..3378
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        3691..4959
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg464_2_AMP-binding.1"
                     /evalue="6.30E-100"
                     /label="ctg464_2_AMP-binding.1"
                     /locus_tag="ctg464_2"
                     /protein_end="943"
                     /protein_start="520"
                     /score="326.3"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FEEQAVLHADAIAAADAGEACPYAGLNARANQLAHTLLAGGLAPE
                     AAVVVLCNRSVKMLAAFIGILKAGGAYVPLSPEFPAARIGDMLRDCGATFLIAESSTIT
                     PGLLAQLRSRVPALRVICLDHGGTMEDAAEGFVNAAAWGTAPAGNPDRRVTPGHLAYIL
                     YTSGSTGMPKGVMIEHRGMLNHLLLKRDDLELTAGSVVAQNASETFDISIWQFLSPLIV
                     GGRTVIYAKDLVLQPAKLLRRVHEDRITILEVVPSYLSVLLTCLEEEQPAGIFAALKFL
                     VVTGETLQKSLVERWFRRFPAIRLVNAYGPTEASDDITHCILAEVPAGVSIPVGRPLPN
                     LNVYVVSHHGQLCPVGVKGEIVVSGVGVGRGYLNQPEKTAHAFIEDPFAPVAGVRMYRT
                     GDVGRWLPDGNVDFLGRIDAQVKVN"
     CDS_motif       3880..3915
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg464_2_0006"
                     /evalue="5.70E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg464_2"
                     /protein_end="595"
                     /protein_start="583"
                     /score="16.4"
                     /tool="antismash"
                     /translation="GILKAGGAYVPLS"
     CDS_motif       4030..4068
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg464_2_0007"
                     /evalue="2.50E+01"
                     /label="Cy2"
                     /locus_tag="ctg464_2"
                     /protein_end="646"
                     /protein_start="633"
                     /score="-1.9"
                     /tool="antismash"
                     /translation="RVPALRVICLDHGG"
     CDS_motif       4168..4227
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg464_2_0008"
                     /evalue="8.50E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg464_2"
                     /protein_end="699"
                     /protein_start="679"
                     /score="33.6"
                     /tool="antismash"
                     /translation="AYILYTSGSTGMPKGVMIEHR"
     CDS_motif       4750..4839
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg464_2_0009"
                     /evalue="1.70E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg464_2"
                     /protein_end="903"
                     /protein_start="873"
                     /score="45.9"
                     /tool="antismash"
                     /translation="PVGVKGEIVVSGVGVGRGYLNQPEKTAHAFI"
     CDS_motif       4927..4992
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg464_2_0010"
                     /evalue="1.30E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg464_2"
                     /protein_end="954"
                     /protein_start="932"
                     /score="36.4"
                     /tool="antismash"
                     /translation="FLGRIDAQVKVNGHRIELGEIER"
     aSDomain        5272..5481
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg464_2_PCP.1"
                     /evalue="1.60E-21"
                     /label="ctg464_2_PCP.1"
                     /locus_tag="ctg464_2"
                     /protein_end="1117"
                     /protein_start="1047"
                     /score="68.0"
                     /tool="antismash"
                     /translation="ERALARIWGEVLGIDAQSVSRHANFFELGGHSLKATTVAGRILKH
                     LHVEVLLRDLFTHQELHKLSAHIDSL"
     CDS_motif       5596..5709
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg464_2_0011"
                     /evalue="2.90E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg464_2"
                     /protein_end="1193"
                     /protein_start="1155"
                     /score="55.0"
                     /tool="antismash"
                     /translation="AYNMPEALHLEGPLDRQRVEDTFRLLIARHESLRTRFVS"
ORIGIN
        1 catcgacggg ctgacgctca accaacgcga aaccgggcac ggcatcgcca agtttgacct
       61 cgaactgctg gtgacggagc aaaaccacgc actgcatttc aacctggaat acgccaccga
      121 cctcttcggg cggaacacgg ttgaacggtt tgccgcctat ttccggcgca ttgccgccgc
      181 cgtgatcgcc gacgccgacg tgcgcatcgg tgacgtggac atgctgccgc cccgggaacg
      241 gcagcaactg ctgctggact tcaacaatac ccgcgccgat tacccggccg gggccaccct
      301 gatggacctt ttcgaggagc aggtccggaa aacgcccggc aacgtcgccg tctgggtgca
      361 gaaccaggcc attacgtacc gggagctttc cgagcggtcc aaccgcatgg cgcattacct
      421 gcgggagcac caaggagtgc ggtgcggcga cctggtcggg ctgctgctgg aaagggaaga
      481 agaaatgttc cccaccattt tcggcatcct caaagccggc gcggcctacg tgcccctgtc
      541 ggtggaccac ccggccgccc gcatcggggc gatccttgcg ggttcgggcc tgaaggtgct
      601 ggtcacgcgg cggcagtacg cggaagcggt acaaacggaa gggccgctgg cgatcctcga
      661 cctcgatgcc gtcgccgggc gcattgcgca gttgccggcc gggccaccgc tcaccaggcc
      721 ccgcgggagc gatctggcct acgtgatcta tacctccggc tccacgggcc gccccaaagg
      781 cgtgatgatc gaacaccact cggtggtaaa ccgcctcctg tggatgcaga aggaatacaa
      841 tttgacggaa gaagacgtgc tgatgcagaa aacgcccctg gtgttcgacg tatcggtgtg
      901 ggagttgttc tggtgggcga tgaccggggc gtcggtgtgc gtactggcgc cgggcgccga
      961 gaaagaaccc gaaaaggtga tgcgggccgt cgaagcctgc cgggtgtcgg tcctccactt
     1021 cgtgccgtcg atgctcagtg cgttcctggg cgccgccgaa gcgcagggta ccgaccggct
     1081 ggcgacgctc cgccacgtat tcgccagcgg cgaagccctc acgcccgacc aggtgcaacg
     1141 gttcggccgg acgctgcacg ccggccacgg cacgcgcctg gtcaacctgt acggccccac
     1201 ggaggcaacc gtcgacgtgt cgtaccacgc gtgcgatttc cggccggccg cttccgtgcc
     1261 catcggcaag cccatcgaca atacgcaact gtacgtgctc gacccgtaca acggcgtgtg
     1321 ccccgtcggc gtggccggcg agttgtgcat cgggggcgcc ggcctggccc gcggctacct
     1381 caacgacgag gcgcaaacgc aggccaaatt cgtgccacac ccgtttgccc gcgaaggccg
     1441 gatctaccgg actggcgacc tggcctgctg gctgcccgac ggctcggtca aattcctggg
     1501 ccgcctcgac caccaggtga agatcagggg cttccggatc gaactggggg agatcgaagc
     1561 ccagctcacg ctgcacccgg cggtaagcga cgccgtggtg ctggtgaccg aacgggcggg
     1621 ccacaaatac ctggtggcct actacgccgc cgccccgctg ccggcggccg aactgaacgg
     1681 gtacctggcg cggcacctcc cgcattacat gatcccgggc tactacgttc acctggaggc
     1741 cttgccgctg acgaccaacg gcaaagtgga ccgcaaaaag ctgccggccc ccgaagccgg
     1801 gcccgccgcg ccctgcgtgc cgccggccac ccccgtggaa gcgaagctgc gccggatctg
     1861 gagcgaagcc ctggccgtgg acgaagacgt gatcagcacc gacagcaact ttttcgagat
     1921 cggcgggcat tcgctcatcg ccaccttcct ggccaaccag gtcgcgaagg aattcgccgt
     1981 cgggttcgac ctgcaggacg tctttaccaa acaaagcatc aaagcgcagg ccgcgcacat
     2041 tgaactggac gactggattt ttgaagcgca gacggacagt gatgaaagca ttcaagtaac
     2101 ggtgtaataa gtaacggtgt aatcacgagc atggaacaat tactgaagca acttaaagaa
     2161 gtcaacgccc gcattacggt tgaaaacggc gacctcaaac tctcttttcc caagggcgtg
     2221 gacgcgtcgg ccctcctgcc ccgggtgaga acgcacaagc aggaactgat cgaatacatc
     2281 gggaaaagaa aaggctccgc gcagcaaacc gccatcggcc cggtcgaaaa acgcgaacat
     2341 tacccgttgt cttcggccca gcgccggctg tacttcctgc acgagatcga cccggcctcg
     2401 ctggcctaca acatgcccct ggtgctcgaa ctggagggag ccctcgaccg gggccgggtg
     2461 gaaaaagctt tcggggaact ggtcggccgg cacgaggcgc tgcgcaccag catccgcaaa
     2521 gccggcgacg aagtggtgca ggtggtgcac gaccacgtgc cgttcgccct ggagtaccac
     2581 gccgccgaag gggcttccct cgacgggata atcgggcagt ttacccgtcc gttcgacctg
     2641 ggacaggccc ccctgatgcg cgccgcgctg gtgacgctcc cggcgggccg gcacgccctg
     2701 ctggtggaca tgcaccacat cgtcgccgac ggcgtgtcca tgcaactgct ttcccgtgat
     2761 ttcatcgcgt gctacaacgg caagccgccc gccccgttgg ccttgcagta caaggactac
     2821 accgcgtggc agcagagcgc cgcgtaccgg cagcaactcg agcgccagcg cgccttctgg
     2881 ctgcacgcat ttgccggcga ggtaagtccg ctggacctgc ccttcgaccg gccgaggccg
     2941 ccggtaaaaa gcttcgccgg ggacagcgtc acgctggtga tggggccgga cgcgacgcgc
     3001 aagctccggg cggttgccga caaggcgggc gccacgatgt tcatgaacct gctcgccatt
     3061 ttcaacgtcc tgctgggcaa actgtccaac cagtccgaca tcgtgatcgg caccccggtg
     3121 tcgggccgcc accacgccga cgcgcaggac atcgtggggg tgttcatcaa tacgctggcc
     3181 ctccgcaaca ccgttgacgg caacctgccg ttcattgatt tcctggcccg ggtgaaagag
     3241 aacacgcggg ccgccctggc cctccaggcc tacccctacg aagaactggt tgaagacctg
     3301 aaaatcccgc gggatgcggg ccacaatccc ctgtttgacg tgatgttctc gtttgagaac
     3361 ctgtccggcg gcgagttaag catgcagggg ctgaaggtcc ggccgtacga caccccgcac
     3421 cgcttcgcca aattcgacct tgaactgatc gccaccgaag caaacgacga actccagctc
     3481 attttcgagt attccaccga cgtattcacc cgggagacga tggaacgttt tgccgcgtac
     3541 ttcgggaaag ccgtgcggga aatcaccgcg aacgacgccc agccggtggg tgccatcgac
     3601 atcctgtccg acgaagagcg gcgcaccatc ctgcacggct tcaacgccac cgcccgggac
     3661 tacccgctgc accggacgtt cgtggacctg tttgaagaac aggccgtcct ccacgcggat
     3721 gccatcgccg ccgccgatgc cggggaagcc tgcccgtacg ccggcctgaa cgcccgcgcc
     3781 aaccaactgg cccacacgct gctggccggc gggctggccc cggaagcggc cgtggtggtg
     3841 ctgtgcaacc gttcggtaaa aatgctggcc gcgttcatcg gcatcctcaa ggcgggcggc
     3901 gcgtacgtgc ccttgtcgcc cgagttcccc gccgcgcgca tcggcgacat gctccgggac
     3961 tgcggggcaa cgttcctgat cgcggaaagc agcacgatca cgcccgggct gctggcgcaa
     4021 ttgcggagcc gggtgcccgc cctccgggtg atctgcctgg accacggcgg gacgatggaa
     4081 gacgccgcgg aaggcttcgt caacgccgcg gcctggggga cggctcccgc cgggaacccg
     4141 gaccggcgcg tgacgcccgg ccacctggcc tacatcctct acacgtcggg ttctaccgga
     4201 atgcccaagg gcgtgatgat cgagcaccgg ggcatgctca accatttgct cctcaagcgc
     4261 gacgacctgg aactgaccgc cgggagcgtc gtggcccaga acgcctccga aaccttcgac
     4321 atttccatct ggcagtttct ctccccgctg atcgtcggcg gccggacggt gatctacgcc
     4381 aaggacctgg tcctgcaacc ggccaaactg ctgcgccgcg tccacgagga ccggattacg
     4441 atcctggaag tcgtgccttc gtacctctcc gtgctgctga cctgcctgga agaggagcag
     4501 cccgccggca ttttcgcggc cctcaaattc ctggtcgtga ccggggagac gctgcaaaag
     4561 tccctcgtgg aaaggtggtt tcgccgtttc cccgccatca ggctggtcaa tgcgtacggc
     4621 ccgacggagg catccgacga catcacgcat tgcatcctgg cggaagtacc ggcgggagtt
     4681 tccatcccgg tgggcagacc gctgcccaac ctgaacgtgt acgtggtcag ccaccacggg
     4741 caactttgcc cggtcggcgt caaaggcgaa atcgtggtat cgggcgtggg cgtggggagg
     4801 ggatacctca accagcccga aaagaccgcg cacgccttca ttgaagaccc ttttgccccg
     4861 gtggccgggg tccgcatgta ccgcaccggc gacgtgggcc ggtggttgcc cgacgggaac
     4921 gttgacttcc tgggccggat cgacgcccag gtaaaagtga acgggcaccg catcgagttg
     4981 ggagagatcg aaagaaccct gtcgggccac gacggcatta ccgaagtggt ggccgtggtg
     5041 ggcgaaaagg agggaagcag gcatttgatc gcctactacg tgtcggccca gccggtgccc
     5101 gccccggccc tgcgcggctt cctgtcggcg cgcctgccgg ggtacatggt gccggcccac
     5161 ctggtacacc tgaaggaact gccgctgacg accaacggca aagtggaccg caaaaaactg
     5221 cccgtaccgg aggtggccgc ggcggcctgc gtggcgcccg agacggcgac cgaacgggca
     5281 ctggcccgca tctggggcga agtgttggga atcgacgcgc aatccgtcag ccggcacgcc
     5341 aacttcttcg aactgggtgg acactccctg aaggccacca cggtggccgg ccggattctc
     5401 aaacacctgc acgtggaagt gttgctcaga gacctgttta cgcaccagga actccacaag
     5461 ctgagcgccc acatcgacag cctcggccgg gcgccgggcg cgggcatcga aagggcgccg
     5521 gaaaaagagt actacgaatt gtcctccacc cagcggcgcc tgttgttcct ccacgaactg
     5581 aacacgactt cgctggcgta caacatgccc gaggcgctcc acctggaagg acccttggac
     5641 cgccaacgcg tggaagacac cttccgcctg ctcatcgccc gccacgagag cctgagaacc
     5701 cgctttgtga gcctgcccca gggcaccgtc cagcaagtcc tgccccaggc cgacttcggg
     5761 ctcgaatac
//
