LOCUS       c00479_3300018..        5739 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300018915.a:Ga0193591_1003864.
ACCESSION   c00479_3300018..
VERSION     c00479_3300018..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 09:26:04
            Original ID  :: 3300018915.a:Ga0193591_1003864
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5739
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     aSDomain        complement(1..921)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg479_1_PKS_KS.1"
                     /evalue="4.60E-108"
                     /label="ctg479_1_PKS_KS.1"
                     /locus_tag="ctg479_1"
                     /protein_end="319"
                     /protein_start="12"
                     /score="353.5"
                     /tool="antismash"
                     /translation="IAVIGMAGRFPGANNLADFWENLKHGKESVKFFSDDELREYHIDE
                     ATLRNPDYVKAKGYLENIDQFDAAFFGYSPQEALRMDPQIRLFHECAWHALEDAGYYPE
                     KWKGQIGMYGGGFTSGQWQATLFASLADDTLDWMSLELISNKDLLTTRVSYNLGLTGPS
                     FSVNTQCSTSLVAIHLASSALIAGECDMALAGGVTINLPPKTGYTYAQDAIISQDGHCR
                     PFDEKANGTIWGDGVGIVALKRLRSALRDGDNIYAVIKGSAINNDGASKSNFTAPSVSG
                     QQHVIRLAQQFAEVDPATIEYVETHG"
     aSModule        1..921
                     /domains="nrpspksdomains_ctg479_1_PKS_KS.1"
                     /incomplete
                     /locus_tags="ctg479_1"
                     /tool="antismash"
                     /type="pks"
     CDS             complement(1..957)
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (12-319). E-value:
                     4.6e-108. Score: 353.5. Matches aSDomain:
                     nrpspksdomains_ctg479_1_PKS_KS.1"
                     /NRPS_PKS="type: PKS/NRPS-like protein"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) hyb_KS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 185.2; E-value:
                     3.5e-56)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg479_1"
                     /sec_met_domain="hyb_KS (E-value: 3.2e-112, bitscore:
                     363.1, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDIAIDNETGFEIAVIGMAGRFPGANNLADFWENLKHGKESVKFF
                     SDDELREYHIDEATLRNPDYVKAKGYLENIDQFDAAFFGYSPQEALRMDPQIRLFHECA
                     WHALEDAGYYPEKWKGQIGMYGGGFTSGQWQATLFASLADDTLDWMSLELISNKDLLTT
                     RVSYNLGLTGPSFSVNTQCSTSLVAIHLASSALIAGECDMALAGGVTINLPPKTGYTYA
                     QDAIISQDGHCRPFDEKANGTIWGDGVGIVALKRLRSALRDGDNIYAVIKGSAINNDGA
                     SKSNFTAPSVSGQQHVIRLAQQFAEVDPATIEYVETHG"
     protocluster    1..5739
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1030:5542](-)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(1031..5542)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..5739
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5739
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     CDS_motif       complement(214..270)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg479_1_0003"
                     /evalue="1.10E-02"
                     /label="PKSI-KS_m4"
                     /locus_tag="ctg479_1"
                     /protein_end="248"
                     /protein_start="229"
                     /score="9.2"
                     /tool="antismash"
                     /translation="DGHCRPFDEKANGTIWGDGV"
     CDS_motif       complement(394..441)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg479_1_0002"
                     /evalue="3.20E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="ctg479_1"
                     /protein_end="188"
                     /protein_start="172"
                     /score="19.1"
                     /tool="antismash"
                     /translation="GPSFSVNTQCSTSLVAI"
     CDS_motif       complement(691..726)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg479_1_0001"
                     /evalue="5.60E+01"
                     /label="PKSI-KS_m4"
                     /locus_tag="ctg479_1"
                     /protein_end="89"
                     /protein_start="77"
                     /score="-1.6"
                     /tool="antismash"
                     /translation="FDAAFFGYSPQEA"
     CDS             complement(1031..5542)
                     /NRPS_PKS="Domain: PKS_AT (181-474). E-value: 3e-92. Score:
                     300.9. Matches aSDomain: nrpspksdomains_ctg479_2_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_KR (795-990). E-value: 9.5e-49.
                     Score: 157.5. Matches aSDomain:
                     nrpspksdomains_ctg479_2_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_DH2 (1041-1253). E-value: 8.7e-29.
                     Score: 92.3. Matches aSDomain:
                     nrpspksdomains_ctg479_2_PKS_DH2.1"
                     /NRPS_PKS="Domain: PCP (1403-1470). E-value: 2.2e-16.
                     Score: 51.6. Matches aSDomain:
                     nrpspksdomains_ctg479_2_PCP.1"
                     /NRPS_PKS="type: PKS/NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     ene_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     tra_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 231.6; E-value: 3.3e-70)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg479_2"
                     /sec_met_domain="PP-binding (E-value: 1.7e-14, bitscore:
                     41.9, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 1.4e-32, bitscore: 100.8,
                     seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.8e-93, bitscore: 300.9,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="ene_KS (E-value: 6.7e-20, bitscore: 58.7,
                     seeds: 19, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 1.7e-29, bitscore: 90.5,
                     seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 3.9e-33, bitscore: 102.5,
                     seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 1.5e-26, bitscore: 80.8,
                     seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="tra_KS (E-value: 2.6e-33, bitscore: 103.1,
                     seeds: 44, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 5.7e-38, bitscore:
                     118.4, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKPNVGHLDNAAGIANIIKAALAIKHKQLPPSVNYDTPNPAIRFE
                     ETPFVVSTRLTEWADAAGHPRRAGVSSYGVGGTNAHVILEEYIPSPAATRPPAPALHLI
                     PVSARSENALHKVRQDLVAFLENHPETRLADVAHTLQNGRRDFAHRTYVLAATPAEAIE
                     KLKAAPAVKKADDVKTVFLFPGQGAQYLNMARELYGECASFRDTLDEGFALYAKLNQVD
                     LKGIIFNDAAEAGNWIYQTRYSQPLLFLFEYALARLLMACGVKPDYMIGHSIGEYTASC
                     ISGVLDLEDAIAIVSKRGELMQSLPTGSMLALMLDRQELETLLPPDLSLAAVNSARMSV
                     VSGTHDAIEAFQAQLRSRNIEGRKLHTSHAFHSHMMDPILEAFEKVVGTTPVKAPQIKY
                     LSNLTGNWTREEDLRRPSYWSSHLRSAVLFKDGVEKIPAHENTVFIEVGPGNTLGTFVK
                     RLSPEARSRSVYSTIRHPQENASDVETLYTLLGRLWQKGIDINWSKVFTHVGCQKVSLP
                     LYAFERKKYWVGGNVYQLAQGAQPAPAGNKFTEKLNNRWIYKPTWSETTLGPDAGPQPA
                     PQRLVFSDGSPFTRYFLGRESAGNPVVIEAGKAFEARYGRYTIDPAEKSHYKRLLEALK
                     DTIGDQEIEVLHFWSLDADPDAAVSAGQVKAVQQRGLLSILYLVQCISAVLPKAKVRAR
                     IVSNNIHNVRYRDLHHPLNATLLGAVTTVPLEYKNITMQSIDLDAAHLREPATGYGLLK
                     PALDGAATEQMLAFRGEKLYARTFEPVALKHEANLATVVKDAGVYLVTGGLGGIGIEMA
                     TYLSGLRRVKLALLGRSDFPERDTWPALIRSGGAVADRIRRIQEMEKNGSEVMVLRADV
                     ADAGSMRSCVARVRDAFGRVDGVLHCAGVAGGNIIQTLDTEYVYDTMASKVFGTLTLEE
                     VLDFSTLDFAMLCSSISSITGTFGQLSYTAANSFLDAFTHFRNSRGPKNVICFNWDIWQ
                     EVGMATKALRELNREDELQIPARNLLGHPLVTGYLPKNDDTVFVSHLDPRVHWVMDEHR
                     ILKQPVLPGATYVEILALIAGQLLESPQFVISNLNFYAPFTAPGEAEKTLVSVLTKEEG
                     GYAFAMKEKYSSDKEGVCVKGKLRRAAGESLPAPVDVAGLVRRCDGRTIADAARELNKD
                     TAFLELGPRWTCLRTIHLGETEGVAVIEMPAAFAADFAAFRFHPAILDIAFNYFAAWKI
                     GQQEYLPFSYKNLVVHQPIAGGRLYSHVQQNAAPDASQETISFRVQLLSESGAVLLSIE
                     EYVLKKVYSDKVKADARKFAPAAAAEPAAADSKDALLAEGILSSEGAAIFDTLLTNLLL
                     TGSADYTQLVVSNNNLDDIRESAAGSDAYAYFKPGKADDKPFTDRPDLSDLYEAPAGKV
                     QEQLCVFFQNFLRINQLGIHDNFFELGISSLDVVEIKIGVEQEFRIELPVAVIFERPTI
                     KALAQFVGDELGGTAQPAAVETAVQLDTIQEGRSLLRKRMAL"
     aSDomain        complement(1133..1333)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg479_2_PCP.1"
                     /evalue="2.20E-16"
                     /label="ctg479_2_PCP.1"
                     /locus_tag="ctg479_2"
                     /protein_end="1470"
                     /protein_start="1403"
                     /score="51.6"
                     /tool="antismash"
                     /translation="EQLCVFFQNFLRINQLGIHDNFFELGISSLDVVEIKIGVEQEFRI
                     ELPVAVIFERPTIKALAQFVGDE"
     aSModule        1133..4999
                     /domains="nrpspksdomains_ctg479_2_PKS_AT.1"
                     /domains="nrpspksdomains_ctg479_2_PKS_KR.1"
                     /domains="nrpspksdomains_ctg479_2_PKS_DH2.1"
                     /domains="nrpspksdomains_ctg479_2_PCP.1"
                     /incomplete
                     /locus_tags="ctg479_2"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(1784..2419)
                     /aSDomain="PKS_DH2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg479_2_PKS_DH2.1"
                     /evalue="8.70E-29"
                     /label="ctg479_2_PKS_DH2.1"
                     /locus_tag="ctg479_2"
                     /protein_end="1253"
                     /protein_start="1041"
                     /score="92.3"
                     /tool="antismash"
                     /translation="WVMDEHRILKQPVLPGATYVEILALIAGQLLESPQFVISNLNFYA
                     PFTAPGEAEKTLVSVLTKEEGGYAFAMKEKYSSDKEGVCVKGKLRRAAGESLPAPVDVA
                     GLVRRCDGRTIADAARELNKDTAFLELGPRWTCLRTIHLGETEGVAVIEMPAAFAADFA
                     AFRFHPAILDIAFNYFAAWKIGQQEYLPFSYKNLVVHQPIAGGRLYSHVQ"
     CDS_motif       complement(2018..2038)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg479_2_0011"
                     /evalue="6.60E+00"
                     /label="PKSI-AT-M_m9"
                     /locus_tag="ctg479_2"
                     /protein_end="1175"
                     /protein_start="1168"
                     /score="0.9"
                     /tool="antismash"
                     /translation="FLELGPRW"
     CDS_motif       complement(2354..2407)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg479_2_0010"
                     /evalue="3.30E-04"
                     /label="PKSI-DH_m2"
                     /locus_tag="ctg479_2"
                     /protein_end="1063"
                     /protein_start="1045"
                     /score="13.3"
                     /tool="antismash"
                     /translation="EHRILKQPVLPGATYVEIL"
     aSDomain        complement(2573..3157)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg479_2_PKS_KR.1"
                     /evalue="9.50E-49"
                     /label="ctg479_2_PKS_KR.1"
                     /locus_tag="ctg479_2"
                     /protein_end="990"
                     /protein_start="795"
                     /score="157.5"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GVYLVTGGLGGIGIEMATYLSGLRRVKLALLGRSDFPERDTWPAL
                     IRSGGAVADRIRRIQEMEKNGSEVMVLRADVADAGSMRSCVARVRDAFGRVDGVLHCAG
                     VAGGNIIQTLDTEYVYDTMASKVFGTLTLEEVLDFSTLDFAMLCSSISSITGTFGQLSY
                     TAANSFLDAFTHFRNSRGPKNVICFNWDIWQEV"
     CDS_motif       complement(2627..2734)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg479_2_0009"
                     /evalue="6.90E-16"
                     /label="PKSI-KR_m4"
                     /locus_tag="ctg479_2"
                     /protein_end="972"
                     /protein_start="936"
                     /score="50.8"
                     /tool="antismash"
                     /translation="LDFAMLCSSISSITGTFGQLSYTAANSFLDAFTHFRN"
     CDS_motif       complement(3056..3154)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg479_2_0008"
                     /evalue="3.70E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg479_2"
                     /protein_end="829"
                     /protein_start="796"
                     /score="22.8"
                     /tool="antismash"
                     /translation="VYLVTGGLGGIGIEMATYLSGLRRVKLALLGRSD"
     CDS_motif       complement(3308..3328)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg479_2_0007"
                     /evalue="8.30E+01"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="ctg479_2"
                     /protein_end="745"
                     /protein_start="738"
                     /score="-2.4"
                     /tool="antismash"
                     /translation="AAHLREPA"
     CDS_motif       complement(3518..3577)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg479_2_0006"
                     /evalue="9.90E+01"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="ctg479_2"
                     /protein_end="675"
                     /protein_start="655"
                     /score="-3.6"
                     /tool="antismash"
                     /translation="DAAVSAGQVKAVQQRGLLSIL"
     aSDomain        complement(4121..4999)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg479_2_PKS_AT.1"
                     /evalue="3.00E-92"
                     /label="ctg479_2_PKS_AT.1"
                     /locus_tag="ctg479_2"
                     /protein_end="474"
                     /protein_start="181"
                     /score="300.9"
                     /specificity="Minowa: mal"
                     /specificity="consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /tool="antismash"
                     /translation="LFPGQGAQYLNMARELYGECASFRDTLDEGFALYAKLNQVDLKGI
                     IFNDAAEAGNWIYQTRYSQPLLFLFEYALARLLMACGVKPDYMIGHSIGEYTASCISGV
                     LDLEDAIAIVSKRGELMQSLPTGSMLALMLDRQELETLLPPDLSLAAVNSARMSVVSGT
                     HDAIEAFQAQLRSRNIEGRKLHTSHAFHSHMMDPILEAFEKVVGTTPVKAPQIKYLSNL
                     TGNWTREEDLRRPSYWSSHLRSAVLFKDGVEKIPAHENTVFIEVGPGNTLGTFVKRLSP
                     EARSRSVYSTIRH"
     CDS_motif       complement(4184..4213)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg479_2_0005"
                     /evalue="3.40E-02"
                     /label="PKSI-AT-M_m9"
                     /locus_tag="ctg479_2"
                     /protein_end="453"
                     /protein_start="443"
                     /score="7.6"
                     /tool="antismash"
                     /translation="FIEVGPGNTLG"
     CDS_motif       complement(4256..4291)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg479_2_0004"
                     /evalue="3.30E-03"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="ctg479_2"
                     /protein_end="429"
                     /protein_start="417"
                     /score="11.0"
                     /tool="antismash"
                     /translation="YWSSHLRSAVLFK"
     CDS_motif       complement(4406..4426)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg479_2_0003"
                     /evalue="9.90E+01"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="ctg479_2"
                     /protein_end="379"
                     /protein_start="372"
                     /score="-3.5"
                     /tool="antismash"
                     /translation="SHMMDPIL"
     CDS_motif       complement(4634..4756)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg479_2_0002"
                     /evalue="1.60E-22"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ctg479_2"
                     /protein_end="303"
                     /protein_start="262"
                     /score="71.8"
                     /tool="antismash"
                     /translation="GVKPDYMIGHSIGEYTASCISGVLDLEDAIAIVSKRGELMQS"
     CDS_motif       complement(4949..5005)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg479_2_0001"
                     /evalue="7.90E-07"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="ctg479_2"
                     /protein_end="198"
                     /protein_start="179"
                     /score="21.2"
                     /tool="antismash"
                     /translation="VFLFPGQGAQYLNMARELYG"
     CDS             complement(5642..5737)
                     /locus_tag="ctg479_3"
                     /transl_table=11
                     /translation="PARRPAVGGSVTTTTPSDGQMRSDTRRARAE"
ORIGIN
        1 gccgtgggtc tccacgtact cgatggtggc cgggtccact tcggcaaact gctgggcgag
       61 ccggatcacg tgttgttgcc ccgatacgct cggcgcggtg aagttcgact tggaggcccc
      121 gtcgttgttg atggccgacc ctttgatgac ggcgtagatg ttgtccccgt cgcggagggc
      181 gctgcggagg cgtttgaggg ccacgatgcc cacgccgtcg ccccagatgg tgccgttggc
      241 tttttcgtcg aacggccggc agtgcccgtc ctgggagatg atcgcgtcct gggcgtaggt
      301 ataccccgtt ttggggggca ggttgatggt tacgcccccg gccagcgcca tgtcgcattc
      361 gccggcgatc agcgcgctgc tggccaggtg gatggcgacc agcgaagtag aacactgggt
      421 attgaccgaa aagctgggcc cggtgagccc caggttgtaa gacacccggg tggtgagcaa
      481 atctttgttc gagatcagtt caagcgacat ccagtcgagc gtgtcgtcgg ccagggaagc
      541 aaacagcgtg gcctgccact gtccgctcgt aaagccgccg ccgtacatgc cgatctggcc
      601 cttccacttc tcggggtaat agccggcgtc ttccagggcg tgccaggcgc attcgtggaa
      661 caaccggatc tgggggtcca tgcgcagggc ttcctgcggg ctgtacccga aaaacgcggc
      721 atcaaactgg tctatgttct ccaggtaccc tttggccttg acgtaatcgg gatttctgag
      781 ggtggcttca tcaatgtggt actcccggag ctcgtcgtcg ctgaagaatt ttacgctctc
      841 tttgccgtgc tttaggttct cccagaagtc agccaggttg tttgcgccgg gaaaccggcc
      901 cgccatgccg atcactgcga tctcaaaccc ggtttcattg tcaattgcga tatccattga
      961 tggtgtagaa tagaaagttg aatgattgct cgaaggtgca gggccggccg ggaagtcgcc
     1021 gggaagctaa ttacagggcc atccgcttgc gcagcaggct gcggccttcc tggatggtgt
     1081 ccagctggac ggccgtttcg actgccgccg gttgggcggt tccgcccagc tcgtcgccca
     1141 cgaattgcgc cagtgctttg atggtgggtc tttcgaagat gacggccacc ggcagctcga
     1201 tgcggaactc ctgttcgacc ccgatcttga tctccacgac gtcgagcgag gaaatgccca
     1261 gctcgaagaa gttgtcgtgg atgcccagtt ggttgatccg caggaagttc tggaagaaaa
     1321 cgcacagttg ctcctgcacc ttgccggccg gcgcttcgta gaggtccgac aggtcggggc
     1381 ggtcggtgaa cggcttgtcg tcggctttgc ccggcttgaa gtaggcgtac gcgtcggacc
     1441 cggcggcgct ctcccggatg tcgtccaggt tgttgttgga aacgacgagc tgggtgtagt
     1501 cggcgctgcc ggtcagcagc aggttggtga gcagcgtgtc gaagatggcg gcgccttcgc
     1561 tgctcaggat gccttccgcc agcagggcgt ctttgctgtc ggccgcggcg ggttcggccg
     1621 cggcggcggg ggcgaatttg cgggcgtcgg cctttacctt gtcgctgtac accttcttga
     1681 gcacgtactc ctcgatggag agcagcaccg cgccggattc cgagagcagt tgcacgcgga
     1741 aggagatcgt ctcctgcgag gcgtcgggcg cggcgttctg ctgcacgtgg ctgtagagcc
     1801 tgccgccggc gatgggctgg tgcacgacca ggtttttgta cgagaacggc aggtattcct
     1861 gctgcccgat cttccaggcc gcgaagtagt tgaaggcaat gtcgaggatg gccgggtgga
     1921 accggaacgc ggcaaaatcg gccgcaaacg cggcgggcat ttcgatcacg gccacccctt
     1981 cggtttcgcc caggtgaatg gtccgcaggc aggtccaccg ggggccgagt tcgaggaacg
     2041 cggtgtcttt gttgagttcc cgggccgcgt cggcgatcgt tcgcccgtcg caccggcgca
     2101 ccagtccggc cacgtccacg ggggccggca ggctctctcc cgccgcccgt ctgagcttgc
     2161 cctttacgca aacgccttcc ttgtcggaac tgtacttctc cttcatggcg aacgcatagc
     2221 cgccctcctc tttggtgagt accgagacca gcgttttttc ggcttcgccg ggggcagtga
     2281 acggcgcgta gaaattcagg ttcgagatca cgaactgcgg ggactccagc aactggccgg
     2341 cgatcagggc gaggatttcc acgtaggtcg ccccgggcag caccggttgc ttgaggatgc
     2401 ggtgttcgtc catcacccag tgtacccgcg ggtcgaggtg ggacacaaac accgtatcgt
     2461 cgtttttggg caggtacccc gtcaccagcg ggtggccgag caggttgcgg gcggggattt
     2521 gcagttcgtc ttcgcggttc agttcccgca gggctttggt ggccatgccc acttcctgcc
     2581 agatgtccca gttgaaacaa atgacgtttt tagggccgcg cgaattgcgg aagtgcgtga
     2641 aggcgtcgag gaacgagttg gccgccgtgt agctcaactg gccgaacgtg ccggtgatgc
     2701 tgctgatgga agagcagagc atggcgaagt ccagcgtcga aaagtccagc acttcttcca
     2761 gcgtcagcgt cccgaacact ttggacgcca tggtgtcgta cacgtactcc gtgtcgaggg
     2821 tctggatgat gttgccgccg gcaaccccgg cgcagtgcag cacgccgtcg acccggccga
     2881 acgcgtcccg gacccgggcc acgcaggacc gcatgctgcc ggcatcggcc acgtcggcgc
     2941 gcagcaccat cacctccgac ccgttttttt ccatttcctg gatgcgccgg atgcggtcgg
     3001 ccaccgcgcc gcccgaccgg atgagggccg gccaggtatc ccgttcgggg aagtcgctgc
     3061 gcccgaggag ggccagtttg acccgccgga ggcccgacag gtaggttgcc atttcgatgc
     3121 cgatgccgcc caggccgccc gtcaccaggt acaccccggc gtctttgacc acggtcgcca
     3181 ggttggcttc gtgtttgagc gccaccggct cgaaggtcct tgcgtacagc ttctcccccc
     3241 ggaaggccag catttgttcg gtcgccgcgc cgtcgagggc cggcttgagc aggccgtagc
     3301 ccgtcgccgg ctcacgcagg tgcgccgcgt cgaggtcgat gctttgcatg gtgatgttct
     3361 tgtattcgag gggcaccgtg gtgacggccc cgagcagcgt ggcgttgagc gggtggtgga
     3421 ggtcgcggta ccgcacgttg tggatgttgt tggacacgat ccgggcccgg actttggcct
     3481 tcggcagcac cgcgctgatg cactgcacca ggtacaggat gctgaggagc ccccgctgct
     3541 gcaccgcttt tacctgcccg gccgatacgg ccgcgtccgg gtcggcgtcg aggctccaga
     3601 agtgcaggac ttcgatttcc tggtccccga tggtgtcttt gagcgcctcc agcaaccgct
     3661 tgtagtggct cttttcggcc gggtcgatgg tgtagcgccc gtaccgggcc tcgaaggcct
     3721 tgccggcttc gatgaccacg gggttgccgg cggactcccg gccgaggaag taccgggtga
     3781 acgggctgcc gtcggaaaag acgagccgct gcggggccgg ttggggtccg gcgtccggcc
     3841 cgagggtcgt ctccgaccag gtgggcttgt aaatccagcg gttgttcagc ttttcggtga
     3901 atttgttgcc ggccggcgcg ggctgggcgc cctgggccag ttggtacacg ttgccgccca
     3961 cccagtactt tttccgttcg aaggcgtaga gcggcagcga cactttctgg catcccacgt
     4021 gcgtaaacac tttcgaccag ttgatgtcga tgcccttctg ccagagccgg ccgagcaggg
     4081 tgtacagcgt ttcgacgtcc gaggcgtttt cctgggggtg gcggatggtg ctgtaaacgc
     4141 tccgcgaacg ggcttccggc gagaggcgct tgacgaacgt acccagcgtg ttgcccgggc
     4201 ctacttcgat gaaaacggtg ttctcgtggg cggggatttt ttccacgccg tccttgaaca
     4261 gtaccgcgct ccgcaggtgc gacgaccagt aggagggccg gcggaggtct tcttcgcggg
     4321 tccagttgcc ggtcaggttg gacaggtact tgatctgcgg cgctttgacc ggggtggtcc
     4381 cgaccacctt ttcgaacgcc tccaggatgg ggtccatcat gtgggagtgg aatgcgtgcg
     4441 acgtgtgcag cttgcggccc tcgatgttgc ggctccggag ctgggcctgg aaagcctcga
     4501 tggcgtcgtg cgttcccgac acgacgctca tgcgggccga gttcaccgcg gccagggaaa
     4561 ggtccggggg caggagggtt tcgagttcct gccggtcgag catgagggcc agcatgctgc
     4621 ccgtgggcag cgactgcatg agttcgccgc gtttgctgac gatggcaatg gcgtcttcca
     4681 ggtcgagcac cccgctgatg caagaggcgg tgtactcgcc gatgctgtgg ccgatcatgt
     4741 aatcgggttt tacgccgcac gccatcagca ggcgggccag ggcgtactca aacaggaaca
     4801 gcagcggctg gctgtaccgg gtctggtaaa tccagttgcc ggcctcggcg gcgtcgttga
     4861 agatgatgcc cttgaggtct acctggttaa gcttcgcgta gagggcaaag ccttcgtcga
     4921 gggtgtcgcg gaaggaggcg cactccccgt acagctcgcg ggccatgttg aggtactgcg
     4981 caccctgtcc cgggaagaga aagaccgtct tgacgtcgtc ggcctttttg acggccgggg
     5041 ccgctttcag cttttcgatg gcctcggccg gggtggcggc cagcacgtac gtccggtgcg
     5101 cgaaatcgcg gcggccgttc tgcaacgtgt gggccacgtc ggccaggcgg gtttccgggt
     5161 ggttctccag gaaggcgacc aggtcctggc gaaccttgtg cagggcgttt tcggaccggg
     5221 ccgaaacggg gatcaggtgc agggccggcg ccggcggccg ggtggcggcg ggcgacggga
     5281 tgtactcttc caggatgacg tgggcgttgg tgccgcccac gccgtagctg ctcaccccgg
     5341 cccttctcgg gtggccggcg gcatcggccc attcggtgag ccgcgtgctc accacgaacg
     5401 gcgtttcttc gaaccggatg gcggggttgg gggtatcgta gttgacgctc ggcggcagtt
     5461 gcttgtgttt gatcgccagg gccgccttga tgatgttggc gatgccggcc gcgttgtcga
     5521 ggtggcccac gttgggcttc accgatccga cctggcagta cccgcgcttg cgggtgttga
     5581 acgcctgcga gagcgcctcg atctcgatgg ggtcgccgat ggccgtgccg gtgcgctggc
     5641 gtcattcggc gcgcgcgcgg cgcgtgtcgc tccgcatctg cccgtcggag ggggtggtcg
     5701 tcgtcacgct gccgcccacg gccggacgcc gcgccggga
//
