LOCUS       c00528_3300018..        6795 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300018915.a:Ga0193591_1002680.
ACCESSION   c00528_3300018..
VERSION     c00528_3300018..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 09:26:04
            Original ID  :: 3300018915.a:Ga0193591_1002680
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6795
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1218
                     /NRPS_PKS="Domain: PKS_KR (47-239). E-value: 5.5e-44.
                     Score: 142.0. Matches aSDomain:
                     nrpspksdomains_ctg528_1_PKS_KR.1"
                     /NRPS_PKS="Domain: PCP (315-382). E-value: 4.5e-21. Score:
                     66.6. Matches aSDomain: nrpspksdomains_ctg528_1_PCP.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg528_1"
                     /sec_met_domain="PP-binding (E-value: 2.9e-22, bitscore:
                     66.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 5.2e-38, bitscore:
                     117.9, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LVEKLYAELFAGGPEQEVAYRNNNRWVKFYDPVVPQPTTAAGRLQ
                     PRATYLVTGGLGQVAFMLARHLLKKYAANVVLTGRTILPAPAQWDDYLRSGSRQQRVVE
                     KIEKLKELGALPGFVTYCAADVADYDGLLRVVQTIEATYGAVSGVIHAAGELGPGAFKA
                     VDALGEDAINAQFRPKINGVLNLYAIFGDQKPGFVWITSSLASVLGGLTFGAYAAANSF
                     MDCFAAMRRGHWYAVNLDGVSGGNEAPIGEAELVEIFEMSLGLPEAGQWVVSPRPLELG
                     HWSAPANATPGAGGQSGTGPGTAPGRYAAAGTGVESALVALWEDFFGISGIGPDDEFFE
                     LGGDSLKAMQLSRRIQKIFGLEIPIDAFFKYPTISSLAAEIDVGLRLMDIEKNKTARPA
                     LNEIII"
     protocluster    1..6795
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1267:6793](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1268..6793
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..6795
                     /SMILES="NCCC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6795
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     aSDomain        142..717
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg528_1_PKS_KR.1"
                     /evalue="5.50E-44"
                     /label="ctg528_1_PKS_KR.1"
                     /locus_tag="ctg528_1"
                     /protein_end="239"
                     /protein_start="47"
                     /score="142.0"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="ATYLVTGGLGQVAFMLARHLLKKYAANVVLTGRTILPAPAQWDDY
                     LRSGSRQQRVVEKIEKLKELGALPGFVTYCAADVADYDGLLRVVQTIEATYGAVSGVIH
                     AAGELGPGAFKAVDALGEDAINAQFRPKINGVLNLYAIFGDQKPGFVWITSSLASVLGG
                     LTFGAYAAANSFMDCFAAMRRGHWYAVNLD"
     aSModule        142..1146
                     /domains="nrpspksdomains_ctg528_1_PKS_KR.1"
                     /domains="nrpspksdomains_ctg528_1_PCP.1"
                     /incomplete
                     /locus_tags="ctg528_1"
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       145..243
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg528_1_0001"
                     /evalue="2.60E-12"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg528_1"
                     /protein_end="81"
                     /protein_start="48"
                     /score="39.3"
                     /tool="antismash"
                     /translation="TYLVTGGLGQVAFMLARHLLKKYAANVVLTGRTI"
     CDS_motif       589..693
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg528_1_0002"
                     /evalue="4.40E-13"
                     /label="PKSI-KR_m4"
                     /locus_tag="ctg528_1"
                     /protein_end="231"
                     /protein_start="196"
                     /score="41.7"
                     /tool="antismash"
                     /translation="FVWITSSLASVLGGLTFGAYAAANSFMDCFAAMRRG"
     aSDomain        946..1146
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg528_1_PCP.1"
                     /evalue="4.50E-21"
                     /label="ctg528_1_PCP.1"
                     /locus_tag="ctg528_1"
                     /protein_end="382"
                     /protein_start="315"
                     /score="66.6"
                     /tool="antismash"
                     /translation="ESALVALWEDFFGISGIGPDDEFFELGGDSLKAMQLSRRIQKIFG
                     LEIPIDAFFKYPTISSLAAEIDV"
     CDS_motif       1012..1038
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg528_1_0003"
                     /evalue="3.30E-03"
                     /label="PCP_mC"
                     /locus_tag="ctg528_1"
                     /protein_end="346"
                     /protein_start="337"
                     /score="10.8"
                     /tool="antismash"
                     /translation="FFELGGDSLK"
     CDS             1268..6793
                     /NRPS_PKS="Domain: Condensation_LCL (69-366). E-value:
                     1.2e-81. Score: 265.7. Matches aSDomain:
                     nrpspksdomains_ctg528_2_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (533-817). E-value: 1.6e-60.
                     Score: 196.5. Matches aSDomain:
                     nrpspksdomains_ctg528_2_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1546-1615). E-value: 5.8e-23.
                     Score: 72.6. Matches aSDomain:
                     nrpspksdomains_ctg528_2_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1632-1840). E-value:
                     3.1e-38. Score: 123.2. Matches aSDomain:
                     nrpspksdomains_ctg528_2_Condensation_LCL.2"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180:Decarboxylase, pyridoxal-dependent (Score: 273.5;
                     E-value: 5e-83)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg528_2"
                     /sec_met_domain="Condensation (E-value: 1.6e-69, bitscore:
                     221.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 4e-54, bitscore:
                     170.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6e-14, bitscore:
                     39.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEFISQLESQNVFVGLDGEDLKISFAGSLSPELIGQIRTHKPLL
                     VDYLKKYNVRAAASAIPAAPRRLCYPLSPGQLRIWFDRHSRPGNDPHILSNQVTLDGEY
                     DIARLVRAIGTVVDRHEALRTVFRPDDNGDICQWVLDREALQFEVRVEDVPAGTDQEAF
                     FADLTATFLRKPFDLENGPLVRCGLFRVAPGEKNVLCFAIHHIVSDGWSMNVLEKDLLT
                     CYEAYGRGLPPALPPLAIQYKDYTLWQLDQLQKNGAQSRAFWLSQFEGDIPVLQFPATH
                     PRPATGSRTLLTYLPKETTAALRNYCRRKGGSTFTGLVATLNVLLSKYTGQRDLVVGTL
                     VSGREHPDLAHQIGYYVNTLALRNQLEPNDSFDDFYGRCKDRVLRALEHQAYPYERLVT
                     DLNGEREAGGGGLFDVLVNLLNLGNAVQHGHAGPISDGVLDLGESQGTFGLEFVFAETE
                     DYISCKLTFNAAMFDPVLMSDCLLNYKRMLAAILRDPARELRRLEYLSDASRKQLLEEF
                     NNSRLAYPKDKTLRELFREQLQQAPDAVALVAAGKEFTCRWLEETSNQFADYLRSAYAV
                     GAGDRIGLCLDQSEWVPVAILAALKAGAAYVPMDSENPAERVRYFMSDSHCKALIDAAA
                     VEAFARHADRYSKLPPPDHQQALLAVIYTSGSTSTPKGVAIRHAGLLNRLYWMWETYPF
                     GPGEVASMRTSIGFVDHLWEFFGPLLRGVKLVIFNKAAVLDLEGFVARLGACGVTRLVL
                     VPSLLKEMLTLEEVTALEALRYWTCSGEYLPASLVEHFYRKFPNHVLLNIYGSTEVTAD
                     ATLYDTSAAHARAAAPVALPALFACHSAEPLHQSLQQNNPYGNVFTGQSAAGGDAAFTG
                     VSLRKQKTLPEYRAFLQRDVAAGVVNVASAKFIGHMTGPVPPVIADLHQCISLLNQNLV
                     KHETSGMATLLERQVLGCFHKLCFDLPDAFYHERVQDAGCALGNITSGGTLSNITALSY
                     ALSSTLGSGINKTGLAEGLRQHGYTGVAVVGSPHCHYSINKAMRILGLGTNAFVACPLD
                     SDDPGRNRDRLRGQIERLRQNNILVLALVGVAGTTESGKIDPLALLADAAQQFGIHFHV
                     DAAFGGAFLFSDKHVAKFDGISRADTVTICGHKQLYLPMGISLCLFRNPDFVKNAEINT
                     YYQARRGSLDLGKYTIEGSRPFSALILHGALQVVGKEGYAEILESNFDKAALFAALAGA
                     REEFQLYQTPTLNIVLYRYVPKHLAEKRAAGALTAGEREELNELNRAIQARQFKNGNSF
                     VSYTELAAGPESTERVVWFRVVMMNPYTTRQHLEEILDEQCALAGELLGKAAAYPAASR
                     KKSVIPIGKPIGNVQIYILDGDQQLVPLGVAGEIYVGGEGVADGYLNSQAHTEQKFIRN
                     RFCEGSNERLYKTGDLGRWLPDGNVEYLGRIDNQVKINGKRADLGEIELALEQSGLVQE
                     AVVTVRRDEKGNDLLVGYVTGAGALDKVALQVHLKAKLPGYMVPGCWVQLDALPLTTSG
                     KVDRKALPAPDFSAFSDGYVAPRSRTEKLLAAAWQHLFGTGRIGIHDNFFQRGGQSLLA
                     MRLVAAIRKAVGFQMEVTTVFQLPTIAQLARFLDENPGRTPARNLVRAPAGEGVPLTEI
                     QKVYWLAIQDRTVSFAYNMTVGWELSGNVVVEKMREAFGQLLERHTILRAVIRYDAEGH
                     LKLYDQGAEATLAAAFLTSDAGELPLERPAVLALYNQESKHPFDLENGPLIRFRLIGNG
                     PGAGVIFCNVHHIISDGFSMDLMLRDLLGLYHRAIGHGAALPLPEITFSFYDYAYTAWL
                     HHQEEEMTSHQDFWRAYLRNRVAVAHL"
     aSDomain        1475..2365
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg528_2_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="1.20E-81"
                     /label="ctg528_2_Condensation_LCL.1"
                     /locus_tag="ctg528_2"
                     /protein_end="366"
                     /protein_start="69"
                     /score="265.7"
                     /tool="antismash"
                     /translation="YPLSPGQLRIWFDRHSRPGNDPHILSNQVTLDGEYDIARLVRAIG
                     TVVDRHEALRTVFRPDDNGDICQWVLDREALQFEVRVEDVPAGTDQEAFFADLTATFLR
                     KPFDLENGPLVRCGLFRVAPGEKNVLCFAIHHIVSDGWSMNVLEKDLLTCYEAYGRGLP
                     PALPPLAIQYKDYTLWQLDQLQKNGAQSRAFWLSQFEGDIPVLQFPATHPRPATGSRTL
                     LTYLPKETTAALRNYCRRKGGSTFTGLVATLNVLLSKYTGQRDLVVGTLVSGREHPDLA
                     HQIGYYVNTLALRNQLE"
     aSModule        1475..6112
                     /complete
                     /domains="nrpspksdomains_ctg528_2_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg528_2_AMP-binding.1"
                     /domains="nrpspksdomains_ctg528_2_PCP.1"
                     /locus_tags="ctg528_2"
                     /monomer_pairings="ala-b -> ala-b"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       1559..1651
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg528_2_0001"
                     /evalue="1.20E-11"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg528_2"
                     /protein_end="128"
                     /protein_start="97"
                     /score="37.0"
                     /tool="antismash"
                     /translation="VTLDGEYDIARLVRAIGTVVDRHEALRTVFRP"
     CDS_motif       1874..1939
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg528_2_0002"
                     /evalue="8.70E-11"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg528_2"
                     /protein_end="224"
                     /protein_start="202"
                     /score="34.2"
                     /tool="antismash"
                     /translation="IHHIVSDGWSMNVLEKDLLTCYE"
     CDS_motif       1988..2023
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg528_2_0003"
                     /evalue="3.50E-03"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg528_2"
                     /protein_end="252"
                     /protein_start="240"
                     /score="10.2"
                     /tool="antismash"
                     /translation="QYKDYTLWQLDQL"
     CDS_motif       2267..2356
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg528_2_0004"
                     /evalue="9.50E-13"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg528_2"
                     /protein_end="363"
                     /protein_start="333"
                     /score="40.5"
                     /tool="antismash"
                     /translation="DLVVGTLVSGREHPDLAHQIGYYVNTLALRN"
     CDS_motif       2405..2524
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg528_2_0005"
                     /evalue="5.10E-10"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg528_2"
                     /protein_end="419"
                     /protein_start="379"
                     /score="31.6"
                     /tool="antismash"
                     /translation="KDRVLRALEHQAYPYERLVTDLNGEREAGGGGLFDVLVNLL"
     aSDomain        2867..3718
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg528_2_AMP-binding.1"
                     /evalue="1.60E-60"
                     /label="ctg528_2_AMP-binding.1"
                     /locus_tag="ctg528_2"
                     /protein_end="817"
                     /protein_start="533"
                     /score="196.5"
                     /specificity="consensus: ala-b"
                     /tool="antismash"
                     /translation="FREQLQQAPDAVALVAAGKEFTCRWLEETSNQFADYLRSAYAVGA
                     GDRIGLCLDQSEWVPVAILAALKAGAAYVPMDSENPAERVRYFMSDSHCKALIDAAAVE
                     AFARHADRYSKLPPPDHQQALLAVIYTSGSTSTPKGVAIRHAGLLNRLYWMWETYPFGP
                     GEVASMRTSIGFVDHLWEFFGPLLRGVKLVIFNKAAVLDLEGFVARLGACGVTRLVLVP
                     SLLKEMLTLEEVTALEALRYWTCSGEYLPASLVEHFYRKFPNHVLLNIYGSTEVTADAT
                     LYDT"
     CDS_motif       3056..3097
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg528_2_0006"
                     /evalue="6.10E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg528_2"
                     /protein_end="610"
                     /protein_start="596"
                     /score="16.3"
                     /tool="antismash"
                     /translation="LAALKAGAAYVPMDS"
     CDS_motif       3248..3301
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg528_2_0007"
                     /evalue="2.00E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg528_2"
                     /protein_end="678"
                     /protein_start="660"
                     /score="23.4"
                     /tool="antismash"
                     /translation="VIYTSGSTSTPKGVAIRHA"
     CDS_motif       5375..5464
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg528_2_0008"
                     /evalue="5.40E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg528_2"
                     /protein_end="1399"
                     /protein_start="1369"
                     /score="37.9"
                     /tool="antismash"
                     /translation="PLGVAGEIYVGGEGVADGYLNSQAHTEQKFI"
     CDS_motif       5552..5617
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg528_2_0009"
                     /evalue="1.60E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg528_2"
                     /protein_end="1450"
                     /protein_start="1428"
                     /score="29.9"
                     /tool="antismash"
                     /translation="YLGRIDNQVKINGKRADLGEIEL"
     aSDomain        5906..6112
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg528_2_PCP.1"
                     /evalue="5.80E-23"
                     /label="ctg528_2_PCP.1"
                     /locus_tag="ctg528_2"
                     /protein_end="1615"
                     /protein_start="1546"
                     /score="72.6"
                     /tool="antismash"
                     /translation="EKLLAAAWQHLFGTGRIGIHDNFFQRGGQSLLAMRLVAAIRKAVG
                     FQMEVTTVFQLPTIAQLARFLDENP"
     aSDomain        6164..6787
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg528_2_Condensation_LCL.2"
                     /domain_subtype="Condensation_LCL"
                     /evalue="3.10E-38"
                     /label="ctg528_2_Condensation_LCL.2"
                     /locus_tag="ctg528_2"
                     /protein_end="1840"
                     /protein_start="1632"
                     /score="123.2"
                     /tool="antismash"
                     /translation="VPLTEIQKVYWLAIQDRTVSFAYNMTVGWELSGNVVVEKMREAFG
                     QLLERHTILRAVIRYDAEGHLKLYDQGAEATLAAAFLTSDAGELPLERPAVLALYNQES
                     KHPFDLENGPLIRFRLIGNGPGAGVIFCNVHHIISDGFSMDLMLRDLLGLYHRAIGHGA
                     ALPLPEITFSFYDYAYTAWLHHQEEEMTSHQDFWRAYLRNRVAVAH"
     aSModule        6164..6787
                     /domains="nrpspksdomains_ctg528_2_Condensation_LCL.2"
                     /incomplete
                     /locus_tags="ctg528_2"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       6227..6343
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg528_2_0010"
                     /evalue="2.30E-10"
                     /label="C2_DCL_024-062"
                     /locus_tag="ctg528_2"
                     /protein_end="1692"
                     /protein_start="1653"
                     /score="32.8"
                     /tool="antismash"
                     /translation="AYNMTVGWELSGNVVVEKMREAFGQLLERHTILRAVIRYD"
     CDS_motif       6563..6628
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg528_2_0011"
                     /evalue="8.10E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg528_2"
                     /protein_end="1787"
                     /protein_start="1765"
                     /score="28.0"
                     /tool="antismash"
                     /translation="VHHIISDGFSMDLMLRDLLGLYH"
ORIGIN
        1 ctggtggaaa aattgtacgc cgaactgttt gccggtggtc cggagcagga agtggcgtac
       61 cggaataaca accggtgggt aaaattctac gaccccgtgg taccccagcc gaccacggcg
      121 gccggcaggt tacagccccg ggctacctac ctggtcacgg gggggttggg acaggtggcc
      181 tttatgctgg cccgccactt gctgaaaaag tacgccgcca acgtggtcct gacgggcagg
      241 actatcctgc cggcccccgc gcagtgggat gactaccttc gttcggggag ccgccagcaa
      301 cgggtcgtcg aaaagattga gaaattgaag gaactgggtg ccctgcccgg gtttgtcacc
      361 tactgtgcgg ccgacgtagc cgactacgac ggcttgctgc gcgtggtgca aactatcgaa
      421 gcaacgtacg gggccgtcag cggggtcatc cacgccgccg gggagctggg gcccggcgct
      481 ttcaaggcgg ttgatgcctt gggggaggac gcaatcaacg cccagttccg gcctaaaatc
      541 aatggggtgc tcaacctgta cgcaatcttt ggggaccaga agcccggttt cgtgtggatc
      601 acttccagcc tggcctccgt cttgggcggt ctcacctttg gcgcctacgc ggccgccaac
      661 agcttcatgg attgtttcgc agccatgcgg cgcgggcact ggtacgccgt caacctcgac
      721 ggcgtatcgg gcggaaacga agctcccatc ggcgaagcgg aactggtcga aatttttgaa
      781 atgtcgctcg gcttgcccga ggcgggtcag tgggtggtgt cgccccgtcc attggaactg
      841 ggccactggt cggctcctgc aaacgccacg ccgggtgccg gcggccagtc cgggacgggt
      901 ccgggcaccg caccgggccg ttatgcggct gccggcaccg gggtagaaag cgccctggtg
      961 gccctgtggg aagacttttt cggcattagc gggattggcc cagacgatga gtttttcgaa
     1021 ctggggggcg attccctcaa agccatgcag ctcagcagaa gaattcagaa aatcttcggc
     1081 ctggaaatcc cgattgatgc cttcttcaaa taccccacca tcagcagtct ggccgccgag
     1141 attgacgttg ggttgcggct catggacata gagaagaaca agaccgccag gccggctctg
     1201 aacgaaatca ttatctgaca agcacaatcc acttaatcac ccgcgggtaa atcgctacgg
     1261 tatgaatatg ctagaattca tcagccagtt ggagtcccaa aatgtatttg ttggcctgga
     1321 cggggaggat ttgaagatca gtttcgccgg cagcctgagc cccgaactga tcgggcagat
     1381 cagaacccat aaaccgctgc tggttgacta cctgaagaaa tacaatgtcc gggcggcggc
     1441 ctccgctatt cccgccgcac cccggcggct gtgttatccc ttgtcgccgg ggcaattgcg
     1501 catctggttt gaccgccact caagaccagg caacgacccc cacattctga gtaaccaggt
     1561 caccctggac ggggaatacg acattgcccg gctggtgcgg gccatcggga ccgtagtaga
     1621 ccggcacgag gccctgcgga ccgttttccg gcccgacgac aacggcgaca tctgccagtg
     1681 ggtactggac cgggaagcat tgcagttcga agtacgggtg gaagacgtcc cggccggcac
     1741 ggaccaggaa gcgttctttg ccgacctcac cgcgacgttt ctccgtaagc cctttgacct
     1801 ggagaacgga cccctggtca ggtgcggttt gttcagggta gccccgggtg aaaaaaatgt
     1861 attgtgcttt gccatccacc acattgtcag cgacgggtgg tcaatgaatg tactggaaaa
     1921 ggacctgctg acctgttacg aggcctatgg ccggggactc ccgccggcct tgccgccgct
     1981 ggccatccag tacaaggact ataccctatg gcagctggac cagttgcaga aaaacggcgc
     2041 ccagtcccgg gctttctggc tgagccagtt tgagggggat atcccggtat tgcagtttcc
     2101 ggcgacccac ccgcggccgg ctaccggcag ccgcaccctg cttacgtacc tgcccaaaga
     2161 aacgaccgct gccctccgga actactgccg ccgcaaaggg gggagtacct ttacggggct
     2221 ggtggcaacc ctcaacgtgc tgctgagcaa gtacaccggt cagcgcgacc tcgtggtggg
     2281 tacgctggtg tcgggccgcg aacaccctga cctggcgcac cagatcggct actacgtcaa
     2341 tacgctcgcc ctccggaacc agcttgaacc caacgacagc ttcgacgatt tttacggccg
     2401 gtgcaaagac cgcgtgctga gggcgctgga acaccaggcg tatccgtacg agcggctcgt
     2461 aaccgacctg aacggggaaa gggaggccgg tgggggaggg ctcttcgacg tactggtcaa
     2521 tctgctcaac ctcggcaacg cggtacagca cgggcacgcc gggcccattt cggacggcgt
     2581 gctggattta ggggaatcgc aggggacgtt cggcctggag tttgtgtttg cggaaaccga
     2641 agactacatt tcctgtaaac tcaccttcaa cgccgcgatg ttcgacccgg tgctgatgag
     2701 tgactgcctg ttgaattaca agcggatgct ggcggcgatc ctgcgggacc ccgcccggga
     2761 gcttcgtcgc ctggagtacc tgtctgacgc gtcccggaaa caattgctgg aagaattcaa
     2821 caattcccgg ctggcgtacc cgaaagacaa aaccctccgg gaactgttca gggagcagtt
     2881 gcagcaggca cccgacgccg tagcactggt ggccgccggc aaagaattta cctgccgctg
     2941 gctggaagaa acctccaatc agtttgccga ctacctgcgc agcgcgtacg ccgtgggggc
     3001 cggcgaccgg atcgggctct gcctggacca gagcgaatgg gtgcccgtgg ccatactggc
     3061 tgcgctcaag gccggggcgg cctacgtgcc gatggacagc gaaaaccccg ccgaacgggt
     3121 ccgttacttc atgagtgaca gccattgcaa ggccctcatt gacgcggcgg ccgtcgaggc
     3181 gtttgcccgc cacgccgacc gttacagcaa actccccccg ccggatcacc agcaggcttt
     3241 actggcagta atatacacgt cgggttcgac cagtacgccc aaaggggtag ccatccgtca
     3301 cgcgggcctg ctcaaccggt tgtactggat gtgggaaacc tacccgtttg gccccggtga
     3361 ggtagccagc atgcgcacgt ccatcggctt tgtggatcac ctctgggagt ttttcggacc
     3421 gctgctgcgg ggcgtcaaac tggtgatttt caacaaagcc gccgtactgg acctggaagg
     3481 cttcgtggcc cgactggggg cctgcggggt taccaggctg gtgctggtgc cttcgttact
     3541 caaagaaatg ctcacgttgg aggaggtgac ggccctggag gcgctccggt actggacgtg
     3601 cagcggcgag tacctcccgg cttcgctggt ggaacacttt taccgcaaat ttcccaacca
     3661 cgtattgctg aacatttacg ggtctacaga agtgaccgct gacgccaccc tgtacgatac
     3721 ctccgccgcc cacgcgcggg ccgccgcccc ggtggcgctc cccgccctgt ttgcctgcca
     3781 ctcggccgaa cccctccacc agagcctgca gcagaacaac ccgtacggga acgtgtttac
     3841 gggccagtcc gcggcggggg gggatgcagc atttaccggg gtgtcgctgc ggaaacaaaa
     3901 aacgctgccc gagtacagag ctttcctgca acgggacgta gcggcgggcg tagtcaacgt
     3961 ggcgtcagcc aaattcatcg ggcacatgac cggtccggtt ccacccgtga ttgccgacct
     4021 gcaccaatgc atcagcctgc tgaaccagaa cctggtgaag cacgaaacgt cgggaatggc
     4081 caccctgctc gaacgccagg tgctggggtg tttccacaaa ttgtgtttcg acctgcccga
     4141 cgcgttttac cacgaacgcg tgcaggacgc cggctgcgcg ctggggaaca ttaccagcgg
     4201 cggcaccctt tccaacatca cggccttgag ctacgccctg tcgagcaccc ttggcagcgg
     4261 catcaataag accgggctgg ccgagggcct gcgccagcac gggtacaccg gcgtcgccgt
     4321 ggtcggttct ccccactgcc actattccat caacaaggcc atgcggatcc tggggctggg
     4381 caccaacgct ttcgtggcgt gccccctgga ttcggatgac cccggccgga accgggaccg
     4441 gctgcgcgga cagattgaga ggctgcggca gaacaatatc ctggtactgg cgctggtggg
     4501 ggtagcgggc actaccgagt cgggaaaaat tgacccgctg gccctgctgg ccgacgccgc
     4561 gcagcaattt ggtattcatt ttcacgtgga tgcggctttt ggcggcgcct tcctgttctc
     4621 cgacaaacac gtcgccaagt tcgacggcat aagccgcgcc gatacggtca ccatttgcgg
     4681 ccacaagcaa ctgtatttgc cgatgggcat cagcctgtgc cttttcagaa acccggattt
     4741 cgtgaaaaac gctgagatca acacgtatta ccaggcccgc cggggcagcc ttgacctggg
     4801 taagtatacc atcgaagggt caaggccgtt ttcggccctg atcctgcacg gggcgttgca
     4861 ggtggtgggt aaagaagggt acgcagaaat cctggaaagc aattttgata aagcagcttt
     4921 gtttgccgcc ctggccggcg cccgggagga gttccaactg taccagaccc ccacgctcaa
     4981 catcgtactg taccggtacg tacccaaaca cctggccgaa aagcgggccg ccggcgccct
     5041 caccgccggg gaacgggagg agttgaacga actcaaccgc gccatccagg ccaggcagtt
     5101 caaaaacggg aactctttcg tgtcctacac cgaactggcc gccggcccgg aaagcaccga
     5161 aagggtggtg tggttccggg ttgtgatgat gaacccgtac accacccggc agcacctgga
     5221 agaaatcctc gacgaacaat gcgccctggc cggcgaactg ctcggtaaag ccgccgctta
     5281 cccggccgcc agccggaaaa aaagcgtgat tcccattggc aagcccattg gcaacgtgca
     5341 gatatacatc ctcgacggcg accagcaact ggtgccccta ggggtagccg gcgagatcta
     5401 cgtgggcggg gagggggtgg ccgacgggta cctcaacagc caggcccata cggagcaaaa
     5461 gttcatccgg aaccggttct gcgaaggcag caacgagcga ctctacaaaa ccggggacct
     5521 gggacgctgg ctgcccgacg gcaacgtcga gtacctggga cgcattgaca accaggtgaa
     5581 gatcaacggc aaacgggcag acctgggcga aatcgaactg gccctagagc agtcgggcct
     5641 ggtgcaagaa gccgtagtga cggtccgccg ggatgaaaaa ggaaatgatt tgctggtggg
     5701 ctacgtaacc ggggccggag ccctcgacaa agtggctttg caggtgcatc tgaaggcgaa
     5761 gctgcccggc tacatggtgc ccgggtgctg ggtgcaactg gatgccctgc cgctgaccac
     5821 aagcggaaaa gtggaccgga aggccttgcc cgctcccgat ttttcggcct tttcggacgg
     5881 gtacgtggcg ccccggagca gaaccgagaa attgctggcc gccgcctggc agcacttgtt
     5941 cggcaccggc cgaatcggca ttcacgacaa cttcttccag cggggcgggc agtcgctgct
     6001 ggccatgcgg ctggttgccg ccatccggaa agcggttggc ttccagatgg aggttactac
     6061 ggttttccaa ctgcccacca ttgcacaact ggcgcgtttc ctcgacgaaa atccggggcg
     6121 gaccccggcc cgcaacctcg tgagagcgcc ggccggggag ggcgttcccc tgacggaaat
     6181 tcagaaggtg tactggctgg ccatccagga ccggaccgtt tccttcgcct acaacatgac
     6241 cgtcggttgg gagttgagtg gaaacgtagt ggtcgaaaag atgcgggagg cgtttgggca
     6301 gttgctcgaa cggcacacca tcctgcgggc cgtgatccgc tacgacgccg aagggcacct
     6361 gaaactctac gaccagggcg cggaggccac ccttgccgcg gctttcctga ccagcgatgc
     6421 cggcgaactc ccgctggagc gacccgccgt actggccctg tacaaccagg aaagcaagca
     6481 cccgttcgac ctggagaacg gcccgctgat ccggttccgg ctgatcggga acggccccgg
     6541 cgccggcgtg atcttctgca acgtgcacca catcatctcg gatggtttct caatggacct
     6601 gatgctcaga gacctgctgg gcctctacca ccgcgcaatc ggtcacgggg cggccctgcc
     6661 cctgccggaa attacctttt cgttctacga ttacgcctat acggcgtggc tccaccacca
     6721 ggaggaggaa atgaccagcc accaagactt ctggcgggct tacctgcgca accgcgtggc
     6781 ggttgcgcac ctgcg
//
