LOCUS       c00735_3300018..        8699 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300018915.a:Ga0193591_1001534.
ACCESSION   c00735_3300018..
VERSION     c00735_3300018..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 09:26:04
            Original ID  :: 3300018915.a:Ga0193591_1001534
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8699
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..8699
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[707:5219](-)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(708..5219)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..8699
                     /SMILES="NC(CS)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..8699
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             346..636
                     /locus_tag="ctg735_1"
                     /transl_table=11
                     /translation="VSGAGWLEGLSTAQLAGLVGGVVVLGLLAAAQVAQGLFFAHLLRQ
                     NGRLLARIEALEERTLRQAQEQIMSRTPRDTWHLWSRVGAPAGADVARNAS"
     CDS             complement(708..5219)
                     /NRPS_PKS="Domain: AMP-binding (622-1024). E-value:
                     3.2e-101. Score: 330.6. Matches aSDomain:
                     nrpspksdomains_ctg735_2_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1133-1202). E-value: 9.5e-26.
                     Score: 81.6. Matches aSDomain:
                     nrpspksdomains_ctg735_2_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (1222-1468). E-value:
                     9.3e-30. Score: 96.4. Matches aSDomain:
                     nrpspksdomains_ctg735_2_Thioesterase.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1228:methionyl-tRNA formyltransferase (Score: 56;
                     E-value: 5.2e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg735_2"
                     /sec_met_domain="AMP-binding (E-value: 6.8e-110, bitscore:
                     355.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.1e-13, bitscore:
                     37.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVPAIGHLLIPLVQHGNATALKARRPGTRAEDQHANRPGEPAPLP
                     PRCAFAGEGTLLLHCIRVLTARGLPLAGVVSADPQVQSFALAADLPVYPSPDDWAATLP
                     GAPVDYLFSIGHHPAIAPDTLGHLRGGVIRYHDGPLPGNDGLPAPARAILRGENKYCIT
                     WQLSGPRGDAGSTLLQPVDIAPDDTALTLHAKCYEAAQAGFAQLVDQLRTDRPGSVRPG
                     WVGLTGPQPQLPVPGRPAGGSILSWHQPAESLSRLCRALDFGPYANPVSLPKILDGTDL
                     LVPVGLRPLDAPSRLAPGTIVELEATHIRVATATRDVRISHVTTPEGASLSPDLLRATR
                     GWGAGYRLPEPPTGYVAAVEAREAVVAPHQAYWAAKLEKTQPTALPFAARLPLVEGRTA
                     PHTVVQDWPLDAQGQPLPADEAGIPAALCAALLVYLHRATGTTGVCVGFANRIPADPEP
                     AFFAPLVPLEAHVEAAAPFPAVRAAVARELNLAGAHQTYCRDLVARIPALRGRPELAAG
                     LTYPVAVCLADSLETLPTTSPAPLTLVVCPGESRYVLLADPARLDAAALRRVAAGLATL
                     LAHALQEPLTPVGKLHVLPDAERHQILYAWNQTEYPYDRSACMHELFEAQVRRTPDAPA
                     VLFGDEVLTYAALNRKANALAGRLRGAGVGPDVLVGICTEKSLEMVIGVLGIQKAGGAY
                     VPLDPQAPRDRLNIVLDDLQLSVLVTQPHLANRFAGCPFAVVAFDAGAEDAGTDENPAS
                     GVTADHLAYVIYTSGSTGIPKGVVVKHRPAINLIEWVNRTFAVGPGDRVLFVNSLGFDL
                     SVYDIFGLLAAGGSVRVAGAEELRDPRRLLDILYREPITFWNSAPATLSQLVPFGEAVP
                     AGGRSHLRLAFLSGDWIPLPMPAWIRTAFPGTQVISLGGATEATVWSNFYPVGALDEQW
                     VSVPYGKPIQNARYHVLDAHLQPVPVGVAGDLYIGGECLAEGYFKRPELNAQKFIADPY
                     GRPGDRLYRTGDLARYWADGNLEFLGRVDHQVKVRGYRIELGEIEAVLSTREDIQEVLV
                     VAGPDPAGGKRLVAYVVAKAGCPPTTADLRAYLKEKLPEYMVPAAFVWLPAFPLNASGK
                     IDRKALPEPLAAQARSGTYLAPRNPFETLLAQIWQEALQLEKVGVADNFFEIGGHSLLA
                     GRVISLIQQITGRLLPLSALFANPTIAQLAVLLKEDSLLDQVWDTLVPIRRAGTRPPLY
                     CIHPVSGDVEYAYKLAPYLPADQPVYGILARGINGVDVPYGTVEEAAAAYVAQIEARQP
                     EGPLHLAGYSYGGLVAYEMARLLAARGRKVESVILFDTYPPNEKYRYKLYGLQYVVLSF
                     LCLLTSMGNLRDFFRNQYWRSLQRRAKSAVKIAASRAGVYAFPANPCGSALQNDTALRD
                     QIRLRLFNVLAKAVQQYQLKPYPGKLVFIRAMEGPARYLSQSDFGWRKNVSGPVAVHNV
                     PGIDHDRIFAEDRHVRSVAAAMHLHLGGSPVPATREAAAETC"
     aSDomain        complement(816..1553)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg735_2_Thioesterase.1"
                     /evalue="9.30E-30"
                     /label="ctg735_2_Thioesterase.1"
                     /locus_tag="ctg735_2"
                     /protein_end="1468"
                     /protein_start="1222"
                     /score="96.4"
                     /tool="antismash"
                     /translation="PLYCIHPVSGDVEYAYKLAPYLPADQPVYGILARGINGVDVPYGT
                     VEEAAAAYVAQIEARQPEGPLHLAGYSYGGLVAYEMARLLAARGRKVESVILFDTYPPN
                     EKYRYKLYGLQYVVLSFLCLLTSMGNLRDFFRNQYWRSLQRRAKSAVKIAASRAGVYAF
                     PANPCGSALQNDTALRDQIRLRLFNVLAKAVQQYQLKPYPGKLVFIRAMEGPARYLSQS
                     DFGWRKNVSGPVAVHNVPGIDHDRI"
     aSModule        816..3353
                     /complete
                     /domains="nrpspksdomains_ctg735_2_AMP-binding.1"
                     /domains="nrpspksdomains_ctg735_2_PCP.1"
                     /domains="nrpspksdomains_ctg735_2_Thioesterase.1"
                     /final_module
                     /locus_tags="ctg735_2"
                     /monomer_pairings="cys -> cys"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(1299..1373)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg735_2_0005"
                     /evalue="1.90E-13"
                     /label="NRPS-te1"
                     /locus_tag="ctg735_2"
                     /protein_end="1307"
                     /protein_start="1282"
                     /score="42.7"
                     /tool="antismash"
                     /translation="QPEGPLHLAGYSYGGLVAYEMARLLA"
     aSDomain        complement(1614..1820)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg735_2_PCP.1"
                     /evalue="9.50E-26"
                     /label="ctg735_2_PCP.1"
                     /locus_tag="ctg735_2"
                     /protein_end="1202"
                     /protein_start="1133"
                     /score="81.6"
                     /tool="antismash"
                     /translation="ETLLAQIWQEALQLEKVGVADNFFEIGGHSLLAGRVISLIQQITG
                     RLLPLSALFANPTIAQLAVLLKEDS"
     CDS_motif       complement(2118..2183)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg735_2_0004"
                     /evalue="2.40E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg735_2"
                     /protein_end="1034"
                     /protein_start="1012"
                     /score="38.7"
                     /tool="antismash"
                     /translation="FLGRVDHQVKVRGYRIELGEIEA"
     aSDomain        complement(2148..3353)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg735_2_AMP-binding.1"
                     /evalue="3.20E-101"
                     /label="ctg735_2_AMP-binding.1"
                     /locus_tag="ctg735_2"
                     /protein_end="1024"
                     /protein_start="622"
                     /score="330.6"
                     /specificity="consensus: cys"
                     /tool="antismash"
                     /translation="FEAQVRRTPDAPAVLFGDEVLTYAALNRKANALAGRLRGAGVGPD
                     VLVGICTEKSLEMVIGVLGIQKAGGAYVPLDPQAPRDRLNIVLDDLQLSVLVTQPHLAN
                     RFAGCPFAVVAFDAGAEDAGTDENPASGVTADHLAYVIYTSGSTGIPKGVVVKHRPAIN
                     LIEWVNRTFAVGPGDRVLFVNSLGFDLSVYDIFGLLAAGGSVRVAGAEELRDPRRLLDI
                     LYREPITFWNSAPATLSQLVPFGEAVPAGGRSHLRLAFLSGDWIPLPMPAWIRTAFPGT
                     QVISLGGATEATVWSNFYPVGALDEQWVSVPYGKPIQNARYHVLDAHLQPVPVGVAGDL
                     YIGGECLAEGYFKRPELNAQKFIADPYGRPGDRLYRTGDLARYWADGNLEFLGRVDHQV
                     KVRG"
     CDS_motif       complement(2268..2357)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg735_2_0003"
                     /evalue="4.00E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg735_2"
                     /protein_end="984"
                     /protein_start="954"
                     /score="41.5"
                     /tool="antismash"
                     /translation="PVGVAGDLYIGGECLAEGYFKRPELNAQKFI"
     CDS_motif       complement(2880..2939)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg735_2_0002"
                     /evalue="1.10E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg735_2"
                     /protein_end="780"
                     /protein_start="760"
                     /score="30.2"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGIPKGVVVKHR"
     CDS_motif       complement(3126..3167)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg735_2_0001"
                     /evalue="4.90E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg735_2"
                     /protein_end="698"
                     /protein_start="684"
                     /score="16.6"
                     /tool="antismash"
                     /translation="LGIQKAGGAYVPLDP"
     misc_feature    complement(4587..4589)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             5723..6652
                     /locus_tag="ctg735_3"
                     /transl_table=11
                     /translation="MPAEVRVFAPATVANVAAGFDILGFALGEPGDQIRIRKTAAPGIV
                     LHNETTFAAMPLDPAANTAGVALQALLDHLGRRDGFEITFLHKIKPGSGIGSSAASSAA
                     AVYGANYLLGEPLTRAELVPFAMEGERLASGTAHADNVAPALLGGFVLVRSYKPLDLIS
                     ITAPPRLFCSIVHPQIELKTEDARKVLKKQISLKDAVVQWGNVAGLIAGLLREDYGLIG
                     RSLQDVIVEPIRSLLIPGYDRIKEAALSAGALGCSISGSGPSLFALSTNEADARKIAAA
                     MLGTCADCGMESESYVSSVNGQGAVILS"
     CDS             6815..8698
                     /gene_functions="other (smcogs) SMCOG1261:hypothetical
                     protein (Score: 386.8; E-value: 2.2e-117)"
                     /gene_kind="other"
                     /locus_tag="ctg735_4"
                     /transl_table=11
                     /translation="MLQHLAALRQQLDGELYTDNARKIMYATDASAYREMPLAVAIPKT
                     TQDLQKLVAFAAKHQISLIPRAAGTSLAGQVVGAGLVVDTGKYLNKILEVNPGERWVRV
                     QPGVVRDELNLFLKPYGLQFGPETSTANRAMIGGMVGNNSCGSNSIVYGSTREHVLEVK
                     ALLADGTETTFKALSASDLEAKCLGVTPGQPVPRGFKPKDDLETRIYRQLRGLLAEPAN
                     QAEIRQHFPKKSVPRRNTGYALDLLLDTEPFTEGAEPFNLCKLIAGSEGTLCLLTEIKL
                     NLIPLPPPENGLLCIHCHTIDESLRANLVAVGYGPSASELIDHYILECTKDNIEQRKNR
                     FFVQGDPGAILVVEIGRNTREEVSAVFARLVADLQSQGLGYHYPVLFGEDTKKVWTLRK
                     AGLGLLTNMPGDAKPVAVIEDTAVDVLDLPAYIRDFNEVLKKHGLYSVHYAHAGSGELH
                     LRPIINLKTAEGNGLFRTIAREIAVLVKKYDGSLSGEHGDGRLRGEFIPYMVGEHNYNL
                     FKQVKALFDPQGLFNPGKIVDTPPMDTFLRYTPGQDTPLYPTVFDFDREGGILRHAEQC
                     NGSGDCRKSHVIGGTMCPSYMATKDERDTTRARANMLREMLTRSDRDNPFSH"
     misc_feature    6827..6829
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 tcccttcgcc cgatttatcc gaatgtggta cgggtgtgtg gctgcgcaga ggttcgggac
       61 ctcacggcca acggatacaa tatcagctcg tgcccaagct ggctcggagc gtaacattag
      121 gagatctatc gtggataggg cccacctaat cgcaaaaagg ttggtgctcg ccggggttta
      181 ttccgtcgcc ggcttattga aactcgtcca tcgcccgggc tcacggcata tccctagggc
      241 tttcggcgta ccagtcccgc tcaaaatcct tctgccgctg gccaaggtcg ccgtggcggc
      301 caccttggcc ttgatgccct ctccaagcgc cgcagcgggg ccggcgtgag cggcgcgggc
      361 tggctggagg gtctctcgac cgcccagctc gcggggctcg tcggcggggt ggtcgtcctc
      421 ggcctgctgg ccgccgcgca ggtcgcccag ggattgttct tcgcccacct gctccgccag
      481 aacgggcgct tgctggcgcg gatcgaagcg ttggaagagc ggaccctccg ccaggcgcag
      541 gaacaaatca tgagccgcac cccgcgggac acctggcatt tgtggtccag ggtgggggca
      601 ccggcgggtg ccgacgtggc ccgcaacgcg tcgtgaacca tccccgccct ttgtccgggc
      661 gggaggattt tttttaaaag tacagtaaac gaataccccg gcgggcctca gcaagtttcg
      721 gccgcggctt cccgggtcgc gggaacgggg ctcccgccca ggtgcaggtg catcgctgcg
      781 gccaccgacc gcacgtgccg gtcctcggcg aaaatccggt cgtggtcaat gcccggcacg
      841 ttgtggaccg ccaccgggcc cgacacgttt ttccgccagc caaagtccga ctgcgatagg
      901 taacgggccg ggccttccat cgcccggatg aataccagct tgccggggta cggtttgagc
      961 tggtactgct gcacggcttt tgccagcaca ttaaacagcc ggaggcggat ctggtcgcgc
     1021 agcgccgtgt cattctggag ggcactcccg caggggttcg ccgggaacgc gtacaccccg
     1081 gcccggctgg cggctatttt cacggccgac tttgcgcgcc gctgcaatga ccgccagtac
     1141 tggttgcgga aaaagtcccg caggttgccc atcgacgtga gcaggcacag gaagctgagc
     1201 accacatact gcaacccgta gagcttgtag cggtactttt cgttgggcgg gtacgtgtca
     1261 aacaggatca cgctttcgac cttacggccg cgggccgcca ggagccgggc catttcgtag
     1321 gcgactaggc cgccgtacga gtaacccgcc aggtgcagcg gcccttcggg ctgccgcgcc
     1381 tcgatctggg ccacgtaggc cgcggcggct tcttccaccg ttccgtacgg cacgtccacg
     1441 ccgttgatgc cccgggccag gatgccgtac acgggctggt cggcgggcag gtagggcgcc
     1501 agcttgtagg cgtactccac gtcgcccgac accgggtgga tgcagtacag cgggggccgg
     1561 gtgccggccc tgcggatggg caccagcgtg tcccacacct ggtccagcag cgaatcttcc
     1621 ttcagcagca ccgccagttg cgcaatggtc gggttggcaa acagggccga cagcggcagc
     1681 aggcgccccg tgatctgctg aatgagggag atcacgcggc ccgccagcag ggagtgcccg
     1741 ccgatctcga agaaattgtc ggccacgccc accttttcca gttgcagggc ttcctgccag
     1801 atttgggcca gcagggtttc aaaggggttg cgcggggcca ggtaggtgcc gctgcgcgcc
     1861 tgggcggcca ggggttcggg cagggccttg cggtcaatct tcccgctggc gttgagcgga
     1921 aaagcgggca gccatacgaa cgcggccgga accatgtact cgggcagctt ttccttcagg
     1981 taagcccgga ggtcggccgt ggtgggcggg caacccgctt tggcaaccac gtaagcaacc
     2041 agccgcttgc cgccggccgg gtccggaccg gccaccacca gcacttcctg aatgtcttcg
     2101 cgggtgctga gcacggcttc gatctcgccc agctcgatgc ggtagccgcg cactttcacc
     2161 tggtggtcta cccggcccag gaactccagg ttgccgtcgg cccagtagcg ggccaggtcg
     2221 ccggtgcggt acagccggtc gccggggcgg ccgtaggggt cggcgatgaa tttctgcgcg
     2281 ttcagttcgg gccgtttgaa gtaaccttcc gccaggcatt cgccgccgat gtagaggtcg
     2341 ccggccacgc ccacgggcac gggttgcagg tgggcgtcga gcacgtggta ccgggcgttc
     2401 tggatgggct tgccgtaggg cacgctcacc cactgctcat cgagagcgcc caccgggtag
     2461 aagttggacc acacggtggc ctccgtcgcg ccgcccaggc tgataacctg cgtgccggga
     2521 aacgccgtcc tgatccacgc gggcatgggg agtggaatcc agtcgccgct gaggaaggcg
     2581 agccgcaggt gactccggcc gccggccggc acggcctccc cgaacggcac cagttgcgac
     2641 agcgtggccg gcgccgaatt ccagaaggtg atgggctcgc ggtacaggat gtcgagcagg
     2701 cgtcgcgggt cgcgcagttc ctccgcgccg gcgacgcgga ccgagccgcc cgccgccagc
     2761 aggccgaaaa tgtcgtatac cgacaggtca aagcccagcg agttgacgaa aagcacccgg
     2821 tcgcccgggc cgacggcaaa cgtgcggttc acccattcga tcaggttgat ggccgggcgg
     2881 tgcttgacca ccacgccctt gggaatgccc gtggagccgg acgtgtaaat gacgtaggcc
     2941 aggtggtcgg ccgtcacgcc gctggccggg ttctcgtcgg tcccggcgtc ttccgcgccc
     3001 gcgtcgaagg ccaccactgc aaagggacag cccgcgaaac ggttcgccag gtgcggctgg
     3061 gtcaccagca cggagagctg caagtcgtcg aggacgatgt tgaggcggtc ccggggcgcc
     3121 tgcgggtcga ggggcacgta agcgccgccc gccttctgga tgcccagcac gccgatcacc
     3181 atttcgaggg atttttccgt gcagatgccc accagcacgt cggggcctac gccggcccct
     3241 cgcagacgcc cggccaaggc gttggccttg cggttcaggg cggcgtaggt gagtacctcg
     3301 tcaccaaaga gcacggccgg ggcgtcgggc gtccgccgga cctgcgcctc gaacaactcg
     3361 tgcatgcagg ccgaacgatc gtatgggtac tcagtctggt tccaggcgta caaaatctgg
     3421 tgccgttccg cgtcgggcag cacgtgcagc ttgcccacgg gcgtcagggg ctcttgcagg
     3481 gcgtgggcca gcagggtagc gaggccggcc gcaacccggc gcagcgccgc ggcgtcgagg
     3541 cgggccgggt cggcaagcag gacgtagcgg gattcgcccg ggcaaaccac cagggtaagg
     3601 ggggcgggtg atgtcgttgg cagcgtctcc agcgagtcgg ccaggcacac ggcaaccggg
     3661 tacgtgaggc ccgcggcgag ttccgggcgg ccacgcagcg ccggaatgcg ggccaccagg
     3721 tcgcggcaat aggtctggtg ggcgccggcc aggttcagtt cgcgggctac ggccgcccgc
     3781 acggcgggga agggagcagc cgcctccacg tgcgcctcca gcggaacgag gggggcaaaa
     3841 aaggcgggtt ccgggtcggc cggaatgcgg ttggcaaagc cgacgcacac gccggtcgtg
     3901 cccgtggccc ggtgcaggta cacgagcagg gcagcgcaca gcgcggcggg aatgccggct
     3961 tcgtccgcag gcagcggctg cccctgcgca tccaggggcc agtcttgcac cacggtgtgc
     4021 ggagccgtac ggccttcaac caggggcagg cgggcggcga agggcagggc ggtgggctgc
     4081 gtcttttcga gtttggcggc ccagtacgcc tggtgcggcg ccacgaccgc ttcccgggct
     4141 tccacggcgg ccacgtagcc ggtgggcggt tcgggcaggc ggtagccggc cccccacccc
     4201 cgggtggcgc gcagcaggtc gggggagagg ctggcccctt cgggcgtggt tacgtggctg
     4261 atgcggacgt cgcgggtggc agtggcaacg cggatgtggg tcgcttccag ttccacaatg
     4321 gtgccgggcg ccagccgcga gggggcgtcg agggggcgca ggccgacggg caccagcagg
     4381 tcggttccgt ccaggatttt gggcagactc accgggttgg cgtacggccc gaaatccagc
     4441 gcccggcaca accggctgag gctttcggcg ggctggtgcc aggagaggat gctgcccccc
     4501 gccggccgcc ccgggaccgg cagttggggt tgcgggccgg taagccccac ccacccgggc
     4561 ctgaccgacc cgggcctgtc ggtccgtaac tggtccacga gttgggcaaa gcccgcctgg
     4621 gcggcctcgt agcatttggc gtgcagggtg agggctgtgt cgtcgggggc aatgtccacc
     4681 ggttgcagga gcgtgctgcc cgcatccccc cgcgggcccg acagttgcca ggtgatgcag
     4741 tatttatttt cgcctcgcaa gatggcccgg gccggggcgg gcaggccgtc gttccccggg
     4801 agggggccgt cgtggtagcg gatcacgccc ccgcggaggt gtccgagggt gtcgggggca
     4861 atggccgggt ggtggccgat gctgaacagg tagtccaccg gggcgccggg cagggtcgcc
     4921 gcccagtcgt cgggcgaggg gtacaccggc aggtcggcgg ccagggcgaa cgactgcacc
     4981 tgcgggtcgg ccgaaaccac gccggcgagg ggaagtcccc gggcggtcag tacccggatg
     5041 cagtgcagca ggagcgtgcc ttccccggcg aaagcgcagc gggggggcag gggcgccggt
     5101 tcaccgggcc ggttggcgtg ttggtcttcc gcccgggtgc cggggcgccg ggccttgagg
     5161 gccgtggcat tgccgtgttg gaccagggga atgaggagat gaccaattgc aggcaccatt
     5221 ttttggggta gtatttatag taaaacttgc ggatgcacgg gcggaaaggc gcaaaagcga
     5281 gccatttctg ccggagtgat cctgcttaat ccctttcttg gtaaaagaag taaatggcga
     5341 ctcaataatc ggcaatttgc gagaaagtcg caagcagtgc ccgtacggac cgttaggcag
     5401 caactgcgct gccggcattt tcaggatgga cggccgccct ttttgcgcgt acctggtggt
     5461 gccggccaat ggtaacgggt tgacgttcaa gggttctttc cgaaccggtg gccgcgcacc
     5521 gcaaccgttc ctgctgcata aatacgataa cttttctgca gcgtagataa ccagcgtcat
     5581 attctaattg ttttttaatc accgcccaaa agggaggccc gccgcttggg gcaaaaaagg
     5641 cccgccggag gggcgccgat tcaaattttg gagtaccttg ccgggggctt ttacccgccc
     5701 cccgatcttt ttttctccgc ttatgccagc agaagtacgc gtatttgccc cggccaccgt
     5761 ggccaacgtt gccgccgggt tcgacattct gggttttgcg ctcggggagc ccggcgacca
     5821 gatccgcatc cgcaagacgg ccgcgccggg catcgtgctg cacaacgaaa ccacctttgc
     5881 cgccatgccg ctcgacccgg ccgccaacac ggcgggcgtg gccctgcaag ccctgctcga
     5941 ccacctgggc cgccgcgacg gcttcgagat cacgttcctg cacaagatca agccgggcag
     6001 cggcatcggc agcagcgcgg cctcctcggc ggcggccgtg tacggggcca actacctgct
     6061 gggcgaaccg ctcacgcgcg cggaactggt gccttttgcc atggagggag aacggctcgc
     6121 cagcggcacg gcccacgccg acaacgtggc cccggccctg ctgggcggct tcgtgctggt
     6181 gcgcagctac aaacccctcg acctgatctc cattacggcc ccgccccggc tgttctgttc
     6241 catcgtgcac ccgcagatcg aactgaagac ggaagacgcc cggaaggtgc tcaaaaagca
     6301 gatttccctc aaagacgccg tggtgcaatg gggcaacgtg gccggcctca tcgcgggcct
     6361 gctgcgcgaa gactacggac tcatcggccg ttccctccag gacgtgatcg tggaaccgat
     6421 tcgctccctg ctcatcccgg gctacgaccg gatcaaggag gcggccctgt cggccggcgc
     6481 cctggggtgc agcatttcgg gttcgggtcc ctccctgttc gccctaagca ccaacgaggc
     6541 cgacgcccgc aaaatcgccg ccgccatgct gggcacctgc gccgactgcg gcatggaaag
     6601 cgaaagttac gtgtcgagtg tcaacggcca gggggccgtg atcctttcgt agcccagccc
     6661 gattgacgat tcaccccgga gacaccgcag gctatttgcc ctaacctttg ttgtcaatac
     6721 gcccagcggc aaggaaaaaa ggcaagaaag cggtaaattt gggtaacgcc cggaaggacc
     6781 gttcggccgg ccgccgcgct tacccccatt ttacatgctc caacacttag cggcgcttcg
     6841 ccaacagctg gacggtgaac tctacaccga caacgcccgg aaaatcatgt acgccacgga
     6901 cgcctcggcc taccgggaaa tgcccctggc cgtagccatc cccaagacca cgcaggacct
     6961 gcaaaagctg gtggccttcg ccgccaaaca ccagatttcg ctcattccgc gggcggcggg
     7021 cacctcgctg gccgggcagg tggtgggcgc ggggctggtg gtggacacag gcaaatacct
     7081 caacaaaatc ctggaagtaa accccggcga acgctgggtg cgggtgcagc cgggcgtggt
     7141 gcgcgacgag ttgaacctgt ttctcaaacc ctacggtttg cagttcggtc ccgaaacctc
     7201 cacggccaac cgggccatga tcggcggcat ggtcggcaac aactcctgcg gctccaactc
     7261 catcgtgtac ggcagcaccc gggaacacgt gctcgaagta aaggccctgc tggccgacgg
     7321 caccgaaacc accttcaagg ccctttccgc gagtgacctg gaagccaagt gcctgggcgt
     7381 gacgcccggc cagccggtgc cgcgcggctt caagcccaaa gacgacctgg aaacccgcat
     7441 ttaccgccaa ctccgggggc tgctggccga gccggccaac caggccgaaa tccggcagca
     7501 ctttcccaaa aagagcgtcc cccgccgcaa caccggctac gccctcgacc tgctgctcga
     7561 caccgaaccc ttcaccgagg gcgccgaacc gttcaacctc tgcaagctga ttgcgggctc
     7621 ggaggggacg ctgtgcctgc tcacggagat caagttgaac ctgattccgc tgccgccgcc
     7681 cgagaacggc ctcctgtgca tccactgcca caccatcgac gagtcgctgc gggccaacct
     7741 ggtggccgtg gggtacggcc ccagcgccag cgaactcatt gaccactaca ttctcgaatg
     7801 caccaaagac aacattgagc agcgcaaaaa ccgctttttc gtgcagggcg accccggcgc
     7861 catcctggtg gtggaaatcg gccgcaacac ccgcgaggaa gtgagtgccg tgtttgcccg
     7921 gctggttgcc gacctgcaaa gccagggcct gggttaccac tacccggtcc tgttcggcga
     7981 agacaccaag aaagtgtgga cgctgcgcaa ggccggcctg ggcctgctca ccaacatgcc
     8041 cggcgacgcc aagccggtag cggtgatcga agatacggcc gtggacgtgc tcgatctgcc
     8101 ggcctacatc cgcgacttca acgaggtgct caaaaagcac ggcctgtact cggtgcacta
     8161 cgcccacgcc ggttcggggg aactgcacct gcggcccatc atcaacctca aaaccgccga
     8221 gggcaacggg ctgttccgca ccattgcccg ggaaatcgcc gtgctggtaa aaaagtacga
     8281 cggcagcctg tcgggcgaac acggcgacgg ccgcctgcgg ggcgagttta tcccgtacat
     8341 ggtcggggaa cacaactaca atctcttcaa gcaggttaag gcgctgttcg acccgcaggg
     8401 cctcttcaac cccgggaaga tcgtggatac gccgccgatg gacacctttc tgcgctacac
     8461 gccgggccag gatacgcccc tttatcccac cgtgtttgac tttgaccggg aaggcggcat
     8521 tctccgccac gccgaacagt gcaacggctc gggcgactgc cgcaagagcc acgtgatcgg
     8581 gggcacgatg tgcccgtcgt acatggcaac caaggatgaa cgcgacacca cccgggccag
     8641 ggccaacatg ctgcgcgaga tgcttacgcg ttcggaccgg gataacccat tttcccacg
//
