3300018933_8 - 20 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

c00001_3300018.. (original name was: 3300018933.a:Ga0193614_1000844)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	NRPS	1	29,890

c00002_3300018.. (original name was: 3300018933.a:Ga0193614_1000574)

Region	Type	From	To	Most similar known cluster		Similarity
Region 2.1	microviridin	1	16,343

c00003_3300018.. (original name was: 3300018933.a:Ga0193614_1000777)

Region	Type	From	To	Most similar known cluster		Similarity
Region 3.1	bacteriocin	23,194	32,501

c00005_3300018.. (original name was: 3300018933.a:Ga0193614_1006108)

Region	Type	From	To	Most similar known cluster		Similarity
Region 5.1	NRPS	1	3,961

c00008_3300018.. (original name was: 3300018933.a:Ga0193614_1000117)

Region	Type	From	To	Most similar known cluster		Similarity
Region 8.1	NRPS	2	31,194
Region 8.2	acyl_amino_acids,NRPS,T1PKS	34,639	126,501

c00009_3300018.. (original name was: 3300018933.a:Ga0193614_1000267)

Region	Type	From	To	Most similar known cluster		Similarity
Region 9.1	NRPS	2	23,855
Region 9.2	NRPS,T1PKS	30,310	76,416

c00010_3300018.. (original name was: 3300018933.a:Ga0193614_1000060)

Region	Type	From	To	Most similar known cluster		Similarity
Region 10.1	NRPS	142,573	171,033

c00014_3300018.. (original name was: 3300018933.a:Ga0193614_1000017)

Region	Type	From	To
Region 14.1	NRPS-like	13,795	56,408
Region 14.2	bacteriocin	184,666	195,511
Region 14.3	NRPS-like	222,112	264,931

c00022_3300018.. (original name was: 3300018933.a:Ga0193614_1002559)

Region	Type	From	To	Most similar known cluster		Similarity
Region 22.1	NRPS	1	8,830

c00028_3300018.. (original name was: 3300018933.a:Ga0193614_1000207)

Region	Type	From	To	Most similar known cluster		Similarity
Region 28.1	terpene	3,739	24,803

c00030_3300018.. (original name was: 3300018933.a:Ga0193614_1002595)

Region	Type	From	To	Most similar known cluster		Similarity
Region 30.1	NRPS	1	8,719

c00034_3300018.. (original name was: 3300018933.a:Ga0193614_1003477)

Region	Type	From	To	Most similar known cluster		Similarity
Region 34.1	NRPS	1	6,397

c00042_3300018.. (original name was: 3300018933.a:Ga0193614_1001164)

Region	Type	From	To	Most similar known cluster		Similarity
Region 42.1	NRPS	1	21,983

c00043_3300018.. (original name was: 3300018933.a:Ga0193614_1001157)

Region	Type	From	To	Most similar known cluster		Similarity
Region 43.1	NRPS	1	22,058

c00044_3300018.. (original name was: 3300018933.a:Ga0193614_1004064)

Region	Type	From	To	Most similar known cluster		Similarity
Region 44.1	T1PKS	1	5,530

c00048_3300018.. (original name was: 3300018933.a:Ga0193614_1000107)

Region	Type	From	To	Most similar known cluster		Similarity
Region 48.1	bacteriocin,NRPS	101,108	132,656

Region	Type	From	To	Similarity
Region 1.1	NRPS	1	29,890
Region 2.1	microviridin	1	16,343
Region 3.1	bacteriocin	23,194	32,501
Region 5.1	NRPS	1	3,961
Region 8.1	NRPS	2	31,194
Region 8.2	acyl_amino_acids,NRPS,T1PKS	34,639	126,501
Region 9.1	NRPS	2	23,855
Region 9.2	NRPS,T1PKS	30,310	76,416
Region 10.1	NRPS	142,573	171,033
Region 14.1	NRPS-like	13,795	56,408
Region 14.2	bacteriocin	184,666	195,511
Region 14.3	NRPS-like	222,112	264,931
Region 22.1	NRPS	1	8,830
Region 28.1	terpene	3,739	24,803
Region 30.1	NRPS	1	8,719
Region 34.1	NRPS	1	6,397
Region 42.1	NRPS	1	21,983
Region 43.1	NRPS	1	22,058
Region 44.1	T1PKS	1	5,530
Region 48.1	bacteriocin,NRPS	101,108	132,656

No secondary metabolite regions were found in these records:: c00004_3300018.. (original name was: 3300018933.a:Ga0193614_1000384); c00006_3300018.. (original name was: 3300018933.a:Ga0193614_1000124); c00007_3300018.. (original name was: 3300018933.a:Ga0193614_1000800); c00011_3300018.. (original name was: 3300018933.a:Ga0193614_1000024); c00012_3300018.. (original name was: 3300018933.a:Ga0193614_1000042); c00013_3300018.. (original name was: 3300018933.a:Ga0193614_1000053); c00015_3300018.. (original name was: 3300018933.a:Ga0193614_1000568); c00016_3300018.. (original name was: 3300018933.a:Ga0193614_1001740); c00017_3300018.. (original name was: 3300018933.a:Ga0193614_1000200); c00018_3300018.. (original name was: 3300018933.a:Ga0193614_1000178); c00019_3300018.. (original name was: 3300018933.a:Ga0193614_1000145); c00020_3300018.. (original name was: 3300018933.a:Ga0193614_1001715); c00021_3300018.. (original name was: 3300018933.a:Ga0193614_1000712); c00023_3300018.. (original name was: 3300018933.a:Ga0193614_1000382); c00024_3300018.. (original name was: 3300018933.a:Ga0193614_1002322); c00025_3300018.. (original name was: 3300018933.a:Ga0193614_1000945); c00026_3300018.. (original name was: 3300018933.a:Ga0193614_1000074); c00027_3300018.. (original name was: 3300018933.a:Ga0193614_1000138); c00029_3300018.. (original name was: 3300018933.a:Ga0193614_1001052); c00031_3300018.. (original name was: 3300018933.a:Ga0193614_1000001); c00032_3300018.. (original name was: 3300018933.a:Ga0193614_1000151); c00033_3300018.. (original name was: 3300018933.a:Ga0193614_1000016); c00035_3300018.. (original name was: 3300018933.a:Ga0193614_1000480); c00036_3300018.. (original name was: 3300018933.a:Ga0193614_1000099); c00037_3300018.. (original name was: 3300018933.a:Ga0193614_1000070); c00038_3300018.. (original name was: 3300018933.a:Ga0193614_1000349); c00039_3300018.. (original name was: 3300018933.a:Ga0193614_1000356); c00040_3300018.. (original name was: 3300018933.a:Ga0193614_1000050); c00041_3300018.. (original name was: 3300018933.a:Ga0193614_1001533); c00045_3300018.. (original name was: 3300018933.a:Ga0193614_1000680); c00046_3300018.. (original name was: 3300018933.a:Ga0193614_1000913); c00047_3300018.. (original name was: 3300018933.a:Ga0193614_1001736)

Compact view

c00001_3300018.. - Region 1 - NRPS

Download region GenBank file

Location: 1 - 29,890 nt. (total: 29,890 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

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Gene details

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 29890:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X) + (gln - ala - thr - val - glu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_1

Search NORINE for peptide: strict or relaxed

AMP-binding (670..1084): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DTEdVGsiVK
Nearest Stachelhaus code:: lys-b
Stachelhaus code match:: 70% (weak)

ctg1_3

Search NORINE for peptide: strict or relaxed

AMP-binding (489..889): gln

NRPSPredictor2: gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: gln

Stachelhaus prediction details:

Stachelhaus sequence:: DAWQFGLIDK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 100% (strong)

AMP-binding (1553..1947): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: DLFNNALTYK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 100% (strong)

AMP-binding (2613..3016): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNVGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

AMP-binding (3682..4081): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DALWLGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 100% (strong)

AMP-binding (4746..5147): glu

NRPSPredictor2: glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DiWHFGqVDK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 80% (moderate)

c00002_3300018.. - Region 1 - microviridin

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Location: 1 - 16,343 nt. (total: 16,343 nt) Show pHMM detection rules used

Region on contig edge.

microviridin: (mvd or mvnA)

Legend:

core biosynthetic genes

additional biosynthetic genes

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Gene details

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c00003_3300018.. - Region 1 - bacteriocin

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Location: 23,194 - 32,501 nt. (total: 9,308 nt) Show pHMM detection rules used

Region on contig edge.

bacteriocin: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

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TTA codons

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Gene details

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c00005_3300018.. - Region 1 - NRPS

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Location: 1 - 3,961 nt. (total: 3,961 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

c00008_3300018.. - Region 1 - NRPS

Download region GenBank file

Location: 2 - 31,194 nt. (total: 31,193 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

reset view

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 1 - 31194:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg8_3

Search NORINE for peptide: strict or relaxed

CAL_domain (50..500): pk

minowa: NH2

Prediction, score:

NH2: 202.3
Acetyl-CoA: 42.4
fatty_acid: 23.7
AHBA: 6.6
shikimic_acid: 0.0

A-OX (1210..1979): X

c00008_3300018.. - Region 2 - NRPS,T1PKS,acyl_amino_acids

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Location: 34,639 - 126,501 nt. (total: 91,863 nt) Show pHMM detection rules used

Region on contig edge.

acyl_amino_acids: NasY
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 34638 - 126501:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pro) + (D-ohmal - ser) + (gly) + (gln - asn)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 4, location 83192 - 126501:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pro) + (D-ohmal - ser) + (gly) + (gln - asn)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg8_70

Search NORINE for peptide: strict or relaxed

AMP-binding (474..900): gln

NRPSPredictor2: gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: gln

Stachelhaus prediction details:

Stachelhaus sequence:: DAWQFGLIDK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 100% (strong)

AMP-binding (1568..1967): asn

NRPSPredictor2: asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 100% (strong)

ctg8_71

Search NORINE for peptide: strict or relaxed

AMP-binding (504..899): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGLIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

ctg8_73

Search NORINE for peptide: strict or relaxed

PKS_AT (536..822): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 79.2%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 186.9
inactive: 104.9
Methoxymalonyl-CoA: 81.6
Methylmalonyl-CoA: 67.0
Propionyl-CoA: 48.4
Ethylmalonyl-CoA: 39.1
2-Methylbutyryl-CoA: 36.3
Isobutyryl-CoA: 33.7
fatty_acid: 31.4
CHC-CoA: 22.9
trans-1,2-CPDA: 21.4
Acetyl-CoA: 19.4
Benzoyl-CoA: 17.8
3-Methylbutyryl-CoA: 0.0

AMP-binding (2564..2966): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHVSLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

ctg8_74

Search NORINE for peptide: strict or relaxed

AMP-binding (1..231): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DAy---A--K
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 40% (weak)

c00009_3300018.. - Region 1 - NRPS

Download region GenBank file

Location: 2 - 23,855 nt. (total: 23,854 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 1 - 23855:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (tyr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg9_1

Search NORINE for peptide: strict or relaxed

AMP-binding (851..1246): tyr

NRPSPredictor2: tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: tyr, bht
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DASTIAAVCK
Nearest Stachelhaus code:: tyr
Stachelhaus code match:: 100% (strong)

c00009_3300018.. - Region 2 - NRPS,T1PKS

Download region GenBank file

Location: 30,310 - 76,416 nt. (total: 46,107 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 30309 - 76416:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Me-ccmal) + (cys) + (asp) + (pro)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg9_43

CAL_domain (178..500): pk

minowa: NH2

Prediction, score:

NH2: 178.2
Acetyl-CoA: 59.6
fatty_acid: 18.1
AHBA: 14.5
shikimic_acid: 8.1

ctg9_44

PKS_AT (650..946): mmal

ATSignature: Methylmalonyl-CoA

Top 3 matches:: Methylmalonyl-CoA: 91.7%; Malonyl-CoA: 79.2%; Ethylmalonyl-CoA: 75.0%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 171.6
Ethylmalonyl-CoA: 153.8
Methoxymalonyl-CoA: 135.6
Isobutyryl-CoA: 103.2
trans-1,2-CPDA: 97.5
2-Methylbutyryl-CoA: 96.3
Benzoyl-CoA: 91.4
Malonyl-CoA: 86.1
Propionyl-CoA: 79.7
CHC-CoA: 71.8
Acetyl-CoA: 56.2
fatty_acid: 48.5
3-Methylbutyryl-CoA: 48.0
inactive: 13.0

ctg9_45

Search NORINE for peptide: strict or relaxed

AMP-binding (516..919): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DmYnfGVLWK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 70% (weak)

ctg9_49

Search NORINE for peptide: strict or relaxed

AMP-binding (463..866): asp

NRPSPredictor2: asp

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asp

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKVGHVGK
Nearest Stachelhaus code:: asp
Stachelhaus code match:: 100% (strong)

ctg9_50

Search NORINE for peptide: strict or relaxed

AMP-binding (507..913): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DAhiTthVVK
Nearest Stachelhaus code:: tyr
Stachelhaus code match:: 60% (weak)

c00010_3300018.. - Region 1 - NRPS

Download region GenBank file

Location: 142,573 - 171,033 nt. (total: 28,461 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 142572 - 171033:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ala - ala)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg10_134

Search NORINE for peptide: strict or relaxed

CAL_domain (52..498): pk

minowa: NH2

Prediction, score:

NH2: 36.0
fatty_acid: 31.9
AHBA: 30.8
shikimic_acid: 23.5
Acetyl-CoA: -1.3

AMP-binding (1190..1584): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: DLFNNALTYK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 100% (strong)

AMP-binding (2247..2641): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: DLFNNALTYK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 100% (strong)

c00014_3300018.. - Region 1 - NRPS-like

Download region GenBank file

Location: 13,795 - 56,408 nt. (total: 42,614 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 13794 - 56408:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg14_23

Search NORINE for peptide: strict or relaxed

AMP-binding (562..999): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: eFtviGGpVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 50% (weak)

c00014_3300018.. - Region 2 - bacteriocin

Download region GenBank file

Location: 184,666 - 195,511 nt. (total: 10,846 nt) Show pHMM detection rules used

bacteriocin: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

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c00014_3300018.. - Region 3 - NRPS-like

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Location: 222,112 - 264,931 nt. (total: 42,820 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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Gene details

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 3, location 222111 - 264931:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg14_208

Search NORINE for peptide: strict or relaxed

AMP-binding (66..465): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: vFmvVGgslK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 40% (weak)

c00022_3300018.. - Region 1 - NRPS

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Location: 1 - 8,830 nt. (total: 8,830 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

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NRPS/PKS domains

Detailed domain annotation

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c00028_3300018.. - Region 1 - terpene

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Location: 3,739 - 24,803 nt. (total: 21,065 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

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c00030_3300018.. - Region 1 - NRPS

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Location: 1 - 8,719 nt. (total: 8,719 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

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resistance

TTA codons

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 8719:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X) + (phe)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg30_1

Search NORINE for peptide: strict or relaxed

AMP-binding (271..683): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVrHFaLlaK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 60% (weak)

ctg30_2

Search NORINE for peptide: strict or relaxed

AMP-binding (508..905): phe

NRPSPredictor2: phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: phe, trp
Single AA prediction:: phe

Stachelhaus prediction details:

Stachelhaus sequence:: DsWTvAGVCK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 80% (moderate)

AMP-binding (1576..1977): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAFWlGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 90% (moderate)

c00034_3300018.. - Region 1 - NRPS

Download region GenBank file

Location: 1 - 6,397 nt. (total: 6,397 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

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other genes

resistance

TTA codons

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 6397:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg34_1

Search NORINE for peptide: strict or relaxed

AMP-binding (690..1085): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGMIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

AMP-binding (1751..2130): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DifHFGGimK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 60% (weak)

c00042_3300018.. - Region 1 - NRPS

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Location: 1 - 21,983 nt. (total: 21,983 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

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other genes

resistance

TTA codons

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 21983:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ile - D-ala) + (D-X) + (thr - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg42_1

Search NORINE for peptide: strict or relaxed

AMP-binding (1..397): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: ile

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGVTFK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 100% (strong)

AMP-binding (1059..1453): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: DLFNNALTYK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 100% (strong)

ctg42_2

Search NORINE for peptide: strict or relaxed

AMP-binding (483..883): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DIFHfGLiiK
Nearest Stachelhaus code:: hpg
Stachelhaus code match:: 70% (weak)

ctg42_3

Search NORINE for peptide: strict or relaxed

AMP-binding (466..875): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNVGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

AMP-binding (1538..1930): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAFTiAAVwK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 80% (moderate)

c00043_3300018.. - Region 1 - NRPS

Download region GenBank file

Location: 1 - 22,058 nt. (total: 22,058 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 22058:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (glu - X) + (D-X - gly)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg43_1

Search NORINE for peptide: strict or relaxed

AMP-binding (505..915): X

NRPSPredictor2: hydrophilic

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAehvGAItK
Nearest Stachelhaus code:: bht
Stachelhaus code match:: 60% (weak)

AMP-binding (2343..2757): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGMIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

ctg43_2

Search NORINE for peptide: strict or relaxed

AMP-binding (536..1022): glu

NRPSPredictor2: glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAKDLGlVDK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 90% (moderate)

AMP-binding (2026..2499): X

NRPSPredictor2: tyr, bht

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: tyr, bht
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DvSqVgAVCK
Nearest Stachelhaus code:: tyr
Stachelhaus code match:: 70% (weak)

c00044_3300018.. - Region 1 - T1PKS

Download region GenBank file

Location: 1 - 5,530 nt. (total: 5,530 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 5530:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg44_1

CAL_domain (48..496): pk

minowa: NH2

Prediction, score:

NH2: 236.8
fatty_acid: 26.1
AHBA: 10.7
shikimic_acid: 6.6
Acetyl-CoA: -4.1

ctg44_2

PKS_AT (654..949): mal

ATSignature: Malonyl-CoA, inactive

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 100.0%; 2-Rhyd-Malonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 188.6
inactive: 148.0
Methoxymalonyl-CoA: 55.4
Methylmalonyl-CoA: 54.6
Propionyl-CoA: 53.0
Isobutyryl-CoA: 34.2
2-Methylbutyryl-CoA: 30.2
CHC-CoA: 28.1
Ethylmalonyl-CoA: 21.1
fatty_acid: 16.8
trans-1,2-CPDA: 16.5
Acetyl-CoA: 14.4
Benzoyl-CoA: 12.2
3-Methylbutyryl-CoA: 8.7

c00048_3300018.. - Region 1 - NRPS,bacteriocin

Download region GenBank file

Location: 101,108 - 132,656 nt. (total: 31,549 nt) Show pHMM detection rules used

Region on contig edge.

bacteriocin: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or TIGR01193)
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

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TTA codons

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains