LOCUS       c00209_3300020..        4111 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300020184.a:Ga0181573_10026447.
ACCESSION   c00209_3300020..
VERSION     c00209_3300020..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 10:18:50
            Original ID  :: 3300020184.a:Ga0181573_10026447
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4111
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..750)
                     /locus_tag="ctg209_1"
                     /transl_table=11
                     /translation="MSNFLRVIFTGILTLSLSVAHAAQVADKDFHPVAADPAFSSGAGP
                     VIAVDAAHANFHTCDGRYIAFCELMKSDGYQVKTNTKKLSAESLADIRLLVVANALSEK
                     NIDPKQNWATPILPAFSESEKNALVEWIKGGGSLLLIADHMPFPGAISDLALHFGVNWG
                     NSYAFAANTQIVEAANKNSLAVIKGPDSNMMTFALDGINATGVQAFPHPVFLGRNPSER
                     VPFITTFTGSAFTLLPGSQVMPLMGLYE"
     protocluster    1..4111
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[778:4111](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(779..4111)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..4111
                     /SMILES="NCC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..4111
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             complement(779..4111)
                     /NRPS_PKS="Domain: AMP-binding (249-635). E-value: 1.2e-87.
                     Score: 285.8. Matches aSDomain:
                     nrpspksdomains_ctg209_2_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (752-820). E-value: 1.2e-18. Score:
                     58.9. Matches aSDomain: nrpspksdomains_ctg209_2_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (841-1101). E-value:
                     9.3e-29. Score: 93.2. Matches aSDomain:
                     nrpspksdomains_ctg209_2_Thioesterase.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     296.8; E-value: 4.1e-90)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg209_2"
                     /sec_met_domain="Condensation (E-value: 6.4e-18, bitscore:
                     51.9, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.2e-97, bitscore:
                     313.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.3e-16, bitscore:
                     48.1, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.6e-12, bitscore:
                     35.0, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 1.5e-09, bitscore: 24.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GRLEFTFPREVTDRIRSYCRAQRCTVFMFLLANFAVMLSQVSGTR
                     DLTIGTPVRSRLRQEFEKLVGFFANTLVLRIDLKKASFVELLASVRTTVIEALANEEVP
                     FEQVVSEVQPERNLGLSPLFQTFFSLQRKDPQILLFDGIDAQMLDTASPSAKFDLSLLF
                     DEYESELHGSFEFNADLLSDARVEMFRAHFSNLVLSHLEEGNSIARSFRSLGQQEQKFI
                     LDSAVEKSTVPSDRTTLWDWVNAGFSETPPSSIAVRRGSEELSYQALKQLSSRIGERLI
                     AQGVRRGDRIGVCLDRDLRLIPALVGVLSVGACYVPIDASFPDSRIEFMLDQASVSVVL
                     LSPNVQDRSCFKNRRQFNWGLESSPGADVQSFGPNPNDTAYICFTSGSTGNPKGVAISH
                     ASAANLLSGMQQLLKLDASDVWAAITTISFDIHVPELFLLLGVGGCIELLNEPESRDPH
                     LLTNILDSSGASVFQATPSTWRVLEVTGWKGRSQLVGLSGGEKLGADLARYLQTRLKAL
                     WNFYGPTETTVWSAAAQITPHQQQGLVPIGRPILNNHLVILDQEGELAPLGVWGELGIG
                     GIGLTAGYLNQPDLTSTRFRIIDLGGVPTRVYRTGDRARLLSDGSFEVSGRLDNQVKVR
                     GVRIEPEEIEATLETHPGVQSAVVSVREIRGEQVLVATVSGDLTAQEKWAGALSAFVRD
                     RLPSTMTPGIWHSMPSLPVMASGKIDRQAVQNRLSQLDVDQSPDSRTGPAPLAGKDLIE
                     LRLGQLWADYLPVQTLDRNANFFSIGGHSLLAVRLLAAVEREFNRQIPLATLFQAPTIA
                     LMSEFLRKADSSQDVWSAAVRMKKGDEPKAVFLIPGAGGNVLYFQDLVQQVPQTYNVYG
                     LQPPGLDGRTPPIDRIPTLARYFLDQVSDIVRSEDLSDIVVLGHSFGGLVAYELARLAQ
                     IEGPRLRMVGILDTAAPQLQEQVGRDWSHREWVLHLSQIASHMFNADVTLTASMLESDS
                     EIDQIQIFYERLVSSGVVPEGTRLEFVSGLIKVYRSNLAASTDLSPPEKAIENLILIRS
                     RDEQPQNLITDAAARNRTFVDLGWADFLGHSIDVLECPGDHLTMLQDKNTDKLWQGLSD
                     RLN"
     aSDomain        complement(809..1588)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg209_2_Thioesterase.1"
                     /evalue="9.30E-29"
                     /label="ctg209_2_Thioesterase.1"
                     /locus_tag="ctg209_2"
                     /protein_end="1101"
                     /protein_start="841"
                     /score="93.2"
                     /tool="antismash"
                     /translation="AVFLIPGAGGNVLYFQDLVQQVPQTYNVYGLQPPGLDGRTPPIDR
                     IPTLARYFLDQVSDIVRSEDLSDIVVLGHSFGGLVAYELARLAQIEGPRLRMVGILDTA
                     APQLQEQVGRDWSHREWVLHLSQIASHMFNADVTLTASMLESDSEIDQIQIFYERLVSS
                     GVVPEGTRLEFVSGLIKVYRSNLAASTDLSPPEKAIENLILIRSRDEQPQNLITDAAAR
                     NRTFVDLGWADFLGHSIDVLECPGDHLTMLQDKNTDKLW"
     aSModule        809..3364
                     /complete
                     /domains="nrpspksdomains_ctg209_2_AMP-binding.1"
                     /domains="nrpspksdomains_ctg209_2_PCP.1"
                     /domains="nrpspksdomains_ctg209_2_Thioesterase.1"
                     /final_module
                     /locus_tags="ctg209_2"
                     /monomer_pairings="gly -> gly"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(1328..1381)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg209_2_0007"
                     /evalue="2.00E-07"
                     /label="NRPS-te1"
                     /locus_tag="ctg209_2"
                     /protein_end="928"
                     /protein_start="910"
                     /score="23.5"
                     /tool="antismash"
                     /translation="VVLGHSFGGLVAYELARLA"
     aSDomain        complement(1652..1855)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg209_2_PCP.1"
                     /evalue="1.20E-18"
                     /label="ctg209_2_PCP.1"
                     /locus_tag="ctg209_2"
                     /protein_end="820"
                     /protein_start="752"
                     /score="58.9"
                     /tool="antismash"
                     /translation="ELRLGQLWADYLPVQTLDRNANFFSIGGHSLLAVRLLAAVEREFN
                     RQIPLATLFQAPTIALMSEFLRKA"
     CDS_motif       complement(2177..2236)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg209_2_0006"
                     /evalue="3.10E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg209_2"
                     /protein_end="645"
                     /protein_start="625"
                     /score="29.0"
                     /tool="antismash"
                     /translation="GRLDNQVKVRGVRIEPEEIEA"
     aSDomain        complement(2207..3364)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg209_2_AMP-binding.1"
                     /evalue="1.20E-87"
                     /label="ctg209_2_AMP-binding.1"
                     /locus_tag="ctg209_2"
                     /protein_end="635"
                     /protein_start="249"
                     /score="285.8"
                     /specificity="consensus: gly"
                     /tool="antismash"
                     /translation="TPPSSIAVRRGSEELSYQALKQLSSRIGERLIAQGVRRGDRIGVC
                     LDRDLRLIPALVGVLSVGACYVPIDASFPDSRIEFMLDQASVSVVLLSPNVQDRSCFKN
                     RRQFNWGLESSPGADVQSFGPNPNDTAYICFTSGSTGNPKGVAISHASAANLLSGMQQL
                     LKLDASDVWAAITTISFDIHVPELFLLLGVGGCIELLNEPESRDPHLLTNILDSSGASV
                     FQATPSTWRVLEVTGWKGRSQLVGLSGGEKLGADLARYLQTRLKALWNFYGPTETTVWS
                     AAAQITPHQQQGLVPIGRPILNNHLVILDQEGELAPLGVWGELGIGGIGLTAGYLNQPD
                     LTSTRFRIIDLGGVPTRVYRTGDRARLLSDGSFEVSGRLDNQVKVRG"
     CDS_motif       complement(2327..2416)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg209_2_0005"
                     /evalue="1.10E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg209_2"
                     /protein_end="595"
                     /protein_start="565"
                     /score="40.1"
                     /tool="antismash"
                     /translation="PLGVWGELGIGGIGLTAGYLNQPDLTSTRFR"
     CDS_motif       complement(2915..2974)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg209_2_0004"
                     /evalue="1.80E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg209_2"
                     /protein_end="399"
                     /protein_start="379"
                     /score="29.6"
                     /tool="antismash"
                     /translation="AYICFTSGSTGNPKGVAISHA"
     CDS_motif       complement(3155..3193)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg209_2_0003"
                     /evalue="4.10E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg209_2"
                     /protein_end="319"
                     /protein_start="306"
                     /score="10.8"
                     /tool="antismash"
                     /translation="GVLSVGACYVPIDA"
     CDS_motif       complement(3722..3841)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg209_2_0002"
                     /evalue="3.30E-18"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg209_2"
                     /protein_end="130"
                     /protein_start="90"
                     /score="58.0"
                     /tool="antismash"
                     /translation="RTTVIEALANEEVPFEQVVSEVQPERNLGLSPLFQTFFSLQ"
     CDS_motif       complement(3887..3976)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg209_2_0001"
                     /evalue="2.10E-13"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg209_2"
                     /protein_end="75"
                     /protein_start="45"
                     /score="42.6"
                     /tool="antismash"
                     /translation="DLTIGTPVRSRLRQEFEKLVGFFANTLVLRI"
ORIGIN
        1 ctcataaaga cccatcagcg gcattacctg tgagcccggt aaaagggtga acgccgatcc
       61 cgtaaaggtt gtaataaacg gcaccctctc agaaggattt ctgccaagaa acaccgggtg
      121 cggaaacgcc tgaacacctg tcgcgtttat cccgtctaaa gcgaaagtca tcatgttcga
      181 atcgggaccc ttgatcaccg ccaacgagtt cttgttggca gcctcgacaa tttgagtgtt
      241 cgccgcaaaa gcataactgt tgccccaatt cacgccaaaa tgaagcgcca ggtcactaat
      301 agcgccgggg aatggcatat gatccgcgat caacaggagt gagccaccac ctttaatcca
      361 ctccaccaat gcgttttttt cagactcgga aaaagccggc aaaatcggcg tggcccaatt
      421 ctgcttcggg tcgatatttt tctcgctgag ggcgtttgcc accacaagca atcggatgtc
      481 cgcaagggat tctgccgaaa gttttttcgt gtttgtcttt acctggtaac cgtcgctctt
      541 cattagctca caaaatgcaa tgtaccgacc gtcacaggta tggaagttcg cgtgggccgc
      601 atccaccgcg attacaggtc cggccccact cgaaaatgcg ggatcagccg ccactgggtg
      661 aaaatcttta tctgccacct gtgcggcgtg agcgacgctc aatgaaagcg taaggattcc
      721 cgtaaaaatt actctcaaaa aattgctcat aagctcgctc ctcagtagat ttgattgctt
      781 agttcagccg atcgctcagc ccctgccaca gtttatccgt atttttatct tgcagcattg
      841 tgaggtgatc ccctgggcat tcaagcacgt cgattgaatg ccccagaaaa tctgcccagc
      901 ctaaatcgac aaacgttctg ttccttgctg ccgcatccgt tatcagattt tgcggctgct
      961 catcgcgcga tcgaataagg attagattct caatcgcttt ctccggtggg gataagtcag
     1021 tcgatgccgc caggttggat cgatatacct tgatcagtcc tgagacaaac tcaagccgtg
     1081 taccctcggg cacgacgccc gaactgacca gacgttcata aaatatctga atctgatcaa
     1141 tttctgaatc actctcgagc atggacgccg tcagcgtgac gtctgcgttg aacatatgcg
     1201 acgcgatttg gcttaggtga aggacccact cgcgatgcga ccaatcccgg cctacctgct
     1261 cttgtagctg cggtgcggcg gtgtcgagga tgcctaccat gcgtaatcgc ggaccctcta
     1321 tctgggcaag gcgggccagt tcgtaggcta caagaccgcc aaaggagtgg ccaagaacca
     1381 cgatatcgct gaggtcctca ctgcgcacaa tatctgagac ctgatccaaa aaatatcggg
     1441 ccagcgtggg gatgcgatcg atcggtggcg tccgtccatc tagccctgga ggctgcaggc
     1501 catatacatt gtaggtctgc ggcacctgtt gaaccaggtc ttgaaaatac agcacatttc
     1561 ctccagcccc cgggatgaga aagacggcct tgggctcatc acctttcttc atccgaaccg
     1621 cagccgacca aacgtcctga ctggaatccg ctttcctgag gaattcgctc atcagcgcaa
     1681 tcgttggcgc ctgaaaaaga gtcgccaacg gaatctgtcg gttgaactcc ctctcaaccg
     1741 ctgcgagcaa gcggaccgca agcagggaat gccctccaat tgagaagaag ttcgcattgc
     1801 ggtccagtgt ctgaaccgga agatagtccg cccacaattg accaagccgt agctcgataa
     1861 gatcctttcc cgctagcggc gctggtcccg ttctcgaatc cggagattga tcaacgtcta
     1921 attgcgataa acgattctgg actgcctgac gatcaatttt cccgctcgcc atgacgggaa
     1981 gcgatggcat ggaatgccaa atgccaggag tcatggtcga gggcagacga tcacggacaa
     2041 aagctgaaag agcaccggcc catttttctt gggcggtaag gtcccccgac acagtagcca
     2101 cgagtacctg ctcgccgcgg atctcccgaa cggacacgac cgcgctctga acgccagggt
     2161 gcgtctcgag agtggcctct atttcttcgg gctcgatgcg aacacctctc accttcacct
     2221 ggttatcgag acggcccgat acctcaaaac ttccatcgga gagaagtctt gcgcgatccc
     2281 cggtacgata gactcgcgtt ggaacaccgc ctaagtcgat gattctgaat cgggtcgacg
     2341 ttaagtcggg ttgattcaga tatcccgccg tcagtcctat accgccaata ccaagctctc
     2401 cccagacgcc cagcggagcc agttctcctt cttgatccaa aattacaagg tggttattca
     2461 ggataggtcg accgattggg acgagtccct gctgctgatg cggggtgatc tgtgcggcgg
     2521 cagaccaaac cgtcgtttcc gtaggcccgt aaaaattcca aagcgccttt aaccgcgttt
     2581 gcagatatcg agcgagatct gcacctagtt tctccccgcc cgacaagcca acaagctgcg
     2641 agcggccctt ccatcctgtt acctccaaca ctctccaggt tgatggggtc gcctggaata
     2701 cgctcgcgcc ggatgagtcc agaatgttgg tgagcagatg gggatcgcgg gactccggct
     2761 catttagaag ctcaatacat ccaccaaccc ctagcagcag aaaaagttcc ggcacatgta
     2821 tgtcaaacga gatagttgtg atggcggccc acacatcaga cgcatcgagc tttagtaact
     2881 gctgcattcc agaaaggaga ttcgcagcgg aggcatggct gatggcgact ccttttgggt
     2941 tgcccgttga tcctgaggtg aagcaaatgt aggccgtatc gttgggattt ggcccaaaag
     3001 attgaacatc cgcacctggt gaagattcca gaccccagtt aaattgacgg cggtttttaa
     3061 agcaagatcg atcctgaaca ttcgggctga gcagaacaac gctcaccgaa gcctggtcca
     3121 gcatgaattc aattcgcgag tccggaaaag acgcatcgat gggaacatag caagctccga
     3181 cgctaagcac tccgacaagc gcggggatca gcctgagatc tcgatcaagg caaactccta
     3241 tgcggtcacc acgacggacg ccttgtgcaa tcagcctttc tccgatccga ctactcaact
     3301 gcttaagcgc ttggtagcta agttcttcac tgccacgtct taccgcgatg ctgctaggcg
     3361 gtgtctcaga aaaacccgcg ttaacccaat cccaaagcgt tgtccggtct gacggaaccg
     3421 tgctcttctc gaccgcacta tccaggataa atttctgctc ctgttgtcca agcgaccgga
     3481 aggaccgggc gatgctattg ccctcttcca gatgactgag cacaagatta gaaaaatgcg
     3541 ctctgaacat ctccacccgt gcgtctgaga gtagatctgc attgaactcg aagctgccgt
     3601 gaagctccga ctcgtattcg tcgaacagca gacttaaatc aaatttggct gacgggcttg
     3661 ccgtatccag catctgcgca tcgatcccgt cgaataaaag gatctgcggg tcctttcgct
     3721 gaagggaaaa aaacgtctgg aagagaggcg ataggcccag atttcgctcc ggctgcactt
     3781 cggagactac ttgctcgaag ggaacctctt catttgcgag cgcttcaatc acggtggttc
     3841 ggacgctggc taacagctcg acaaacgacg cctttttcaa atcgatccga aggaccaacg
     3901 tgtttgcaaa aaacccgaca agcttttcga actcttggcg taaacgcgac cttaccggcg
     3961 ttccaattgt gaggtctcga gtacctgaaa cctgcgacag catgaccgca aagtttgcta
     4021 gaaggaacat aaagacagtg cagcgctgcg ccctgcagta gcttcgaatt ctgtcggtta
     4081 cctctcgagg aaaagtaaat tccaatcggc c
//
