LOCUS       c00055_3300022..        7655 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300022885.a:Ga0222662_1002237.
ACCESSION   c00055_3300022..
VERSION     c00055_3300022..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 20:34:29
            Original ID  :: 3300022885.a:Ga0222662_1002237
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7655
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..7655
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2634:7653](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(2635..7653)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..7655
                     /SMILES="NC(CC(=O)N)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..7655
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             complement(3..2537)
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (11-435). E-value:
                     2.6e-150. Score: 492.7. Matches aSDomain:
                     nrpspksdomains_ctg55_1_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_DHt (471-633). E-value: 1.5e-09.
                     Score: 29.8. Matches aSDomain:
                     nrpspksdomains_ctg55_1_PKS_DHt.1"
                     /NRPS_PKS="type: PKS/NRPS-like protein"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) hyb_KS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 247.1; E-value:
                     5.6e-75)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg55_1"
                     /sec_met_domain="hyb_KS (E-value: 3.6e-157, bitscore:
                     510.6, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSKLRNYEDTIAVVGMHIRVPGADSLNQYWTNLRDGIDSITFFS
                     DDELRAAGVDDRTLNDPDYVKAAGKLDGIEDFDASFFDMTPKEAEILDPQHRLLMEGVW
                     RALEHAAIDPEQYPGRIGLYAGVGFNGYLVHHILTNPELLESAGAWQLSLNNDKDFATT
                     RVAYKFNLQGPAISINTACSTSLVATCLAAQSLLNHQCDTAIAGGSSIHLPQDRGYHFM
                     TGGTLSPDGHCRPFDAKAAGTIDGNGAASIVLKRYEDAINDKDTIYAVIRGFAINNDGS
                     VKVGYTAPSVEGQADVIMEALEMADVNPDQIDFIETHGTGTDLGDSVEIAALAEGFKTS
                     KKPCTIGSVKSNIGHLDTAAGVAGLIKVILGMQNQIIPPTCHFESPNPTLGLEKTPFFV
                     NNQPIDWSVSMNKPRLAGVSSFGIGGTNAHVIVEQPPEVQSPDDEPEWIVLPISAKSAR
                     ALVDIMVLLAGHIESNPDQSLSNIAYTLQTGRRQYEYRLALILHAGNRQSAGKMIREIS
                     SSIETELSESNHKESSMDSNKTSSKSTSSGSNPDNLTDIKHPNPIQFANGAGEILRKYS
                     SNSIDEARKAGATEELCQSAHVWFNGKSPDWETQSPNRNKVAIPGHPFYKQRYWIEPKK
                     GLFQNEDSVSSNMKPVTKEPSIDNWFYLPGWRKTISGQSQIKSGSKWLILGDNTGITDS
                     LFQLLNSSDAEVKIIFDKKSHSGKGATIDTTSFDDWELYLNSLKDFKPEHIIHAGLFQI
                     QADRDKLLSLAFDGMIALGQALGHSYFSNEIDLVLIADGLMAFEHTNELNPVKTTALGP
                     LRVLAQEYPNINTRVIDIDKNVRPSVLLAELTS"
     aSDomain        complement(639..1124)
                     /aSDomain="PKS_DHt"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg55_1_PKS_DHt.1"
                     /evalue="1.50E-09"
                     /label="ctg55_1_PKS_DHt.1"
                     /locus_tag="ctg55_1"
                     /protein_end="633"
                     /protein_start="471"
                     /score="29.8"
                     /tool="antismash"
                     /translation="ESNPDQSLSNIAYTLQTGRRQYEYRLALILHAGNRQSAGKMIREI
                     SSSIETELSESNHKESSMDSNKTSSKSTSSGSNPDNLTDIKHPNPIQFANGAGEILRKY
                     SSNSIDEARKAGATEELCQSAHVWFNGKSPDWETQSPNRNKVAIPGHPFYKQRYWIEPK
                     "
     aSModule        639..2504
                     /domains="nrpspksdomains_ctg55_1_PKS_KS.1"
                     /domains="nrpspksdomains_ctg55_1_PKS_DHt.1"
                     /incomplete
                     /locus_tags="ctg55_1"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(1233..2504)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg55_1_PKS_KS.1"
                     /evalue="2.60E-150"
                     /label="ctg55_1_PKS_KS.1"
                     /locus_tag="ctg55_1"
                     /protein_end="435"
                     /protein_start="11"
                     /score="492.7"
                     /tool="antismash"
                     /translation="IAVVGMHIRVPGADSLNQYWTNLRDGIDSITFFSDDELRAAGVDD
                     RTLNDPDYVKAAGKLDGIEDFDASFFDMTPKEAEILDPQHRLLMEGVWRALEHAAIDPE
                     QYPGRIGLYAGVGFNGYLVHHILTNPELLESAGAWQLSLNNDKDFATTRVAYKFNLQGP
                     AISINTACSTSLVATCLAAQSLLNHQCDTAIAGGSSIHLPQDRGYHFMTGGTLSPDGHC
                     RPFDAKAAGTIDGNGAASIVLKRYEDAINDKDTIYAVIRGFAINNDGSVKVGYTAPSVE
                     GQADVIMEALEMADVNPDQIDFIETHGTGTDLGDSVEIAALAEGFKTSKKPCTIGSVKS
                     NIGHLDTAAGVAGLIKVILGMQNQIIPPTCHFESPNPTLGLEKTPFFVNNQPIDWSVSM
                     NKPRLAGVSSFGIGGTNAHVIVEQPP"
     CDS_motif       complement(1455..1499)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg55_1_0003"
                     /evalue="5.30E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="ctg55_1"
                     /protein_end="361"
                     /protein_start="346"
                     /score="12.4"
                     /tool="antismash"
                     /translation="GSVKSNIGHLDTAAGV"
     CDS_motif       complement(1551..1598)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg55_1_0002"
                     /evalue="1.20E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="ctg55_1"
                     /protein_end="329"
                     /protein_start="313"
                     /score="11.3"
                     /tool="antismash"
                     /translation="FIETHGTGTDLGDSVEI"
     CDS_motif       complement(1974..2021)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg55_1_0001"
                     /evalue="1.50E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="ctg55_1"
                     /protein_end="188"
                     /protein_start="172"
                     /score="17.2"
                     /tool="antismash"
                     /translation="GPAISINTACSTSLVAT"
     CDS             complement(2635..7653)
                     /NRPS_PKS="Domain: Aminotran_3 (182-518). E-value: 6.4e-53.
                     Score: 171.6. Matches aSDomain:
                     nrpspksdomains_ctg55_2_Aminotran_3.1"
                     /NRPS_PKS="Domain: Condensation_LCL (591-889). E-value:
                     1.2e-71. Score: 233.0. Matches aSDomain:
                     nrpspksdomains_ctg55_2_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1053-1468). E-value:
                     4.6e-94. Score: 307.0. Matches aSDomain:
                     nrpspksdomains_ctg55_2_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1575-1642). E-value: 1.3e-19.
                     Score: 61.9. Matches aSDomain:
                     nrpspksdomains_ctg55_2_PCP.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013:aminotransferase class-III (Score: 285; E-value:
                     1.6e-86)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_2"
                     /sec_met_domain="Condensation (E-value: 5.2e-58, bitscore:
                     183.5, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.7e-103, bitscore:
                     332.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 8.1e-16, bitscore:
                     45.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="SRPQDDLPGLDVNRIRDSISNAVDTPKWTGANPISASQSDLEAIF
                     ASQIRATSSALNELIERQLNFLNQTSGKSDGTSRLHSGISSTPGSTSSNAAELAQEPKK
                     PRSQSAVQPQKMLSPLEIRARGLTETQQAHLEKLIREFNAKTGKSKAHTQKYRSVLADS
                     RAAIGFRFSTKEMLYPLVSNRARGSRVWDLDGNEYIDITMGQGVSLFGHHPEFIETPLK
                     EIVLEGVEMGPRPDHVGEVAEIICEMTGFDRVTFTNSGTEAVMAAMRLARAATKRDKIV
                     SFEGAWHGHADSVMGMRVEEIDGIPVTKPVSPGTPMGAVADQFVLVYDDPDSLEFIRKH
                     GDSIAAVLVEPVQSRNPKVQPAEFLQKLRSLTNEIGALLIFDEMITGFRTHPGGAQAWF
                     NIKADMATYGKVVGGGLPIGVVAGRSDLMDPIDGGAWHYGDNSYPLVNRVVFGGTFCQH
                     PLAMTASLAALKHLKENSPKLQLDLNAKTKKLADHLNQWFLDEEIAIEVAHFGSLFRFE
                     FNTNLELLFYHMNLRGIFVWEWRNCFLSTAHTDQDIDRIIEVVKESVNAMRDGGFIPPK
                     NDPTSKKESQIQSTPQTVDLSTAQKQLATLSGISTEGSMAYHISPLISLKGHVDSDALS
                     SAIQEVVNRHESLRTVVPDTEKQTLLPKLVVPLKIVNFTKEKDAGKACQIWLKEHACKP
                     FELSTGPLLQVHLLKWSDSDSYLVLKGHHIVLDGLSMNLIIHEIARFYNQILSKEPGSL
                     SDRKSDSEPLQFQEYLKWQEGQSFKNQEEYWLNEMSGDLPILELPADKPKPVVPSYKGG
                     RVSREMDPILIDTIRKFSTKNNATHFMTLFSLYTLWLHRLSGQTEIIVGMPVAGRSLKG
                     SENLIGYCTHLIPIRSKYDPKESFLTYLKRMRGTLLNGYQHQDYPFSRLIDKLGAAKKS
                     SSGVPIQSIFNLDRPGDIPSFNELEVNWESQNVYHVAFDLVFNLTEVGNRMTLECDYSE
                     DKFVVSSIERFVDYFENLARNVMERPDGEVGLISLMNDREWKRWIMKWNKTEHAYPAEK
                     SLPELFESVAKKHAKDVAVVWNDGNLLYDELNIQSNKLAHWLSENGIGRSSRVAIFLDR
                     SPELFIAMMGVLKSGAAYIPMDKQYPSERISYMLEDASPELIITTKELSKNIDKSTISK
                     LFMDDDASKWAKMKKKNLKTEHDPLDIAYIMYTSGSTGKPKGTLIHHKGLLNYLTWAQE
                     YYKTSDGIGSPLHSSIAFDATITSLFTPLISGRTVHIVPTDGIEIEHITRCLIDKNGKP
                     TADWSMVKITPAHLELLNAMIPDDKKSGLTRSFVLGGEALLSKTIAPWRKHAPKTRIIN
                     EYGPTETVVGCAIYDEKRTEFSSYNVPIGKPIWNTQLYVLDQNRFPVPPGVEGELYIGG
                     DGVAEGYLNHDDLTKQRFIPVSETGLVHGPKPILTGILYQTGDRVKMLSDSNLVFLGRY
                     DSQFKLRGYRIEPAEIEFALASFKSVKVAVVTIQHLDQGDRLVAYLTLNTGAEFNRADI
                     QLHLSELLPEYMIPSHFEVLESIPLNSNGKIDYKSLPKPSISQSDSINNFVEGSSEQRI
                     AQIWCDFLDVDVVGINDNFFEIGGHSMLVLPMKDRLSKEFNKDVTPVDIFRYPTVSALA
                     NFLSPSPLQYDMDETASASLAGRKKRSTVKFKKK"
     aSDomain        complement(2728..2928)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg55_2_PCP.1"
                     /evalue="1.30E-19"
                     /label="ctg55_2_PCP.1"
                     /locus_tag="ctg55_2"
                     /protein_end="1642"
                     /protein_start="1575"
                     /score="61.9"
                     /tool="antismash"
                     /translation="EQRIAQIWCDFLDVDVVGINDNFFEIGGHSMLVLPMKDRLSKEFN
                     KDVTPVDIFRYPTVSALANFLSP"
     aSModule        2728..5880
                     /complete
                     /domains="nrpspksdomains_ctg55_2_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg55_2_AMP-binding.1"
                     /domains="nrpspksdomains_ctg55_2_PCP.1"
                     /locus_tags="ctg55_2"
                     /monomer_pairings="asn -> asn"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(3220..3285)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg55_2_0008"
                     /evalue="1.70E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg55_2"
                     /protein_end="1478"
                     /protein_start="1456"
                     /score="29.8"
                     /tool="antismash"
                     /translation="FLGRYDSQFKLRGYRIEPAEIEF"
     aSDomain        complement(3250..4494)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg55_2_AMP-binding.1"
                     /evalue="4.60E-94"
                     /label="ctg55_2_AMP-binding.1"
                     /locus_tag="ctg55_2"
                     /protein_end="1468"
                     /protein_start="1053"
                     /score="307.0"
                     /specificity="consensus: asn"
                     /tool="antismash"
                     /translation="FESVAKKHAKDVAVVWNDGNLLYDELNIQSNKLAHWLSENGIGRS
                     SRVAIFLDRSPELFIAMMGVLKSGAAYIPMDKQYPSERISYMLEDASPELIITTKELSK
                     NIDKSTISKLFMDDDASKWAKMKKKNLKTEHDPLDIAYIMYTSGSTGKPKGTLIHHKGL
                     LNYLTWAQEYYKTSDGIGSPLHSSIAFDATITSLFTPLISGRTVHIVPTDGIEIEHITR
                     CLIDKNGKPTADWSMVKITPAHLELLNAMIPDDKKSGLTRSFVLGGEALLSKTIAPWRK
                     HAPKTRIINEYGPTETVVGCAIYDEKRTEFSSYNVPIGKPIWNTQLYVLDQNRFPVPPG
                     VEGELYIGGDGVAEGYLNHDDLTKQRFIPVSETGLVHGPKPILTGILYQTGDRVKMLSD
                     SNLVFLGRYDSQFKLRG"
     CDS_motif       complement(3394..3483)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg55_2_0007"
                     /evalue="3.60E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg55_2"
                     /protein_end="1420"
                     /protein_start="1390"
                     /score="48.0"
                     /tool="antismash"
                     /translation="PPGVEGELYIGGDGVAEGYLNHDDLTKQRFI"
     CDS_motif       complement(4015..4074)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg55_2_0006"
                     /evalue="4.60E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg55_2"
                     /protein_end="1213"
                     /protein_start="1193"
                     /score="28.4"
                     /tool="antismash"
                     /translation="AYIMYTSGSTGKPKGTLIHHK"
     CDS_motif       complement(4267..4308)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg55_2_0005"
                     /evalue="5.90E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg55_2"
                     /protein_end="1129"
                     /protein_start="1115"
                     /score="13.3"
                     /tool="antismash"
                     /translation="MGVLKSGAAYIPMDK"
     CDS_motif       complement(4876..4947)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg55_2_0004"
                     /evalue="3.00E-07"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg55_2"
                     /protein_end="926"
                     /protein_start="902"
                     /score="22.7"
                     /tool="antismash"
                     /translation="RGTLLNGYQHQDYPFSRLIDKLGAA"
     aSDomain        complement(4987..5880)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg55_2_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="1.20E-71"
                     /label="ctg55_2_Condensation_LCL.1"
                     /locus_tag="ctg55_2"
                     /protein_end="889"
                     /protein_start="591"
                     /score="233.0"
                     /tool="antismash"
                     /translation="QTVDLSTAQKQLATLSGISTEGSMAYHISPLISLKGHVDSDALSS
                     AIQEVVNRHESLRTVVPDTEKQTLLPKLVVPLKIVNFTKEKDAGKACQIWLKEHACKPF
                     ELSTGPLLQVHLLKWSDSDSYLVLKGHHIVLDGLSMNLIIHEIARFYNQILSKEPGSLS
                     DRKSDSEPLQFQEYLKWQEGQSFKNQEEYWLNEMSGDLPILELPADKPKPVVPSYKGGR
                     VSREMDPILIDTIRKFSTKNNATHFMTLFSLYTLWLHRLSGQTEIIVGMPVAGRSLKGS
                     ENLIGYCTHLIPIRSKYD"
     CDS_motif       complement(4996..5085)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg55_2_0003"
                     /evalue="5.00E-07"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg55_2"
                     /protein_end="886"
                     /protein_start="856"
                     /score="22.2"
                     /tool="antismash"
                     /translation="EIIVGMPVAGRSLKGSENLIGYCTHLIPIRS"
     CDS_motif       complement(5428..5490)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg55_2_0002"
                     /evalue="1.40E-07"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg55_2"
                     /protein_end="742"
                     /protein_start="721"
                     /score="24.1"
                     /tool="antismash"
                     /translation="HHIVLDGLSMNLIIHEIARFYN"
     CDS_motif       complement(5698..5808)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg55_2_0001"
                     /evalue="8.10E-12"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg55_2"
                     /protein_end="652"
                     /protein_start="615"
                     /score="37.5"
                     /tool="antismash"
                     /translation="AYHISPLISLKGHVDSDALSSAIQEVVNRHESLRTVVP"
     aSDomain        complement(6100..7107)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg55_2_Aminotran_3.1"
                     /evalue="6.40E-53"
                     /label="ctg55_2_Aminotran_3.1"
                     /locus_tag="ctg55_2"
                     /protein_end="518"
                     /protein_start="182"
                     /score="171.6"
                     /tool="antismash"
                     /translation="NRARGSRVWDLDGNEYIDITMGQGVSLFGHHPEFIETPLKEIVLE
                     GVEMGPRPDHVGEVAEIICEMTGFDRVTFTNSGTEAVMAAMRLARAATKRDKIVSFEGA
                     WHGHADSVMGMRVEEIDGIPVTKPVSPGTPMGAVADQFVLVYDDPDSLEFIRKHGDSIA
                     AVLVEPVQSRNPKVQPAEFLQKLRSLTNEIGALLIFDEMITGFRTHPGGAQAWFNIKAD
                     MATYGKVVGGGLPIGVVAGRSDLMDPIDGGAWHYGDNSYPLVNRVVFGGTFCQHPLAMT
                     ASLAALKHLKENSPKLQLDLNAKTKKLADHLNQWFLDEEIAIEVAHFGSLFRFEFN"
ORIGIN
        1 tttgatgtaa gttcagctaa tagaacggag ggccgtacat ttttatctat atcaataacc
       61 cgtgtgttga tattcggata ttcttgagct aaaacacgaa gaggacccaa tgcggtggtc
      121 ttgaccggat ttagttcgtt cgtatgctcg aatgccatga ggccatcggc tatcagtacc
      181 aaatcgattt cattgctgaa atatgaatgt cctaaggctt gcccgagtgc tatcatccca
      241 tcaaatgcca atgataatag cttgtcacgg tcggcttgaa tttggaaaag tccggcgtga
      301 ataatgtgtt cgggtttgaa atcttttagg ctatttaaat agagttccca atcatcaaaa
      361 gaggtcgtat caatggttgc accttttccg gaatgggatt ttttatcgaa gataattttc
      421 acttcagcat cggaactgtt gagtagttgg aaaagtgaat ctgtgattcc ggtgttgtcg
      481 cctaagatta accatttact accggatttg atttgagatt ggccggaaat ggtttttcgc
      541 caacccggca aatagaacca attatcgatt gaaggttctt tggtgacagg tttcatattc
      601 gacgaaactg aatcctcgtt ttgaaagagt ccttttttag gttcaatcca atatcgctgt
      661 ttataaaatg ggtgtccggg aattgcaact ttattgcgat tgggtgattg tgtttcccaa
      721 tctggggact ttccgttaaa ccaaacatgt gccgattggc agagttcctc cgtagcacct
      781 gcttttctgg cttcatcaat tgagtttgaa ctgtatttcc gcaatatttc ccctgcaccg
      841 ttagcaaatt gaattgggtt tgggtgcttg atatcggtca gattatctgg gttactgccg
      901 gatgaggtac tttttgacga agttttgttc gaatccatcg aactctcttt atgattcgac
      961 tccgagagtt cagtctcaat tgatgaggaa atttcgcgaa tcatttttcc tgccgattga
     1021 cgatttccgg catgaaggat caaagcaagt cggtattcat actgacggcg acctgtttgc
     1081 aatgtgtaag cgatgttaga gagtgactga tcaggatttg attcaatatg tccggcaaga
     1141 agaaccataa tatcaaccaa ggctcgggca gactttgcag agataggaag tacaatccat
     1201 tccggttcat cgtctggtga ttgtacttcg ggcggttgct ctacaattac atgtgcattt
     1261 gttcccccga taccaaaaga actgactccg gcaaggcgag gtttattcat gctgactgac
     1321 caatcaatag gctgattatt gacaaaaaat ggtgtttttt ccaagccaag ggttggattt
     1381 ggtgactcaa aatgacaagt agggggaatg atttggttct gcatccctaa tatcacctta
     1441 atcaatccgg caacaccggc ggctgtgtca aggtgtccta tgttgctttt aacagagcca
     1501 atagtacaag gttttttgct tgttttgaac ccttcagcaa gtgcagcgat ttcaacagaa
     1561 tcacctaaat cagtcccggt tccatgtgtc tcaatgaagt caatttgatc gggattgaca
     1621 tccgccattt cgagtgcttc cataataaca tctgcctgtc cttcaacact cggagccgta
     1681 tacccgactt tcacggaccc atcattattt atggcaaaac cacgaattac ggcgtatata
     1741 gtatccttgt catttatagc atcttcataa cgcttcaaaa cgatggatgc cgctccattc
     1801 ccatcaattg tcccggctgc tttggcatca aagggcctgc aatggccgtc cggagataat
     1861 gtacctccag tcataaaatg atatccacgg tcttgtggta agtggataga gctccctcct
     1921 gcgattgcag tatcacactg atggttcaat agactctgag cggccaaaca tgttgcaacc
     1981 aatgaggtag aacatgcagt attaatactg attgccggac cctgcagatt aaatttataa
     2041 gcaactcggg ttgttgcaaa gtctttatca ttattcaaac tgagttgcca agcgccggca
     2101 ctttcaagaa gttcgggatt tgtcagtata tgatggacta aatagccatt aaatccaaca
     2161 cccgcataaa gtccgatgcg acccggatac tgttccggat caatagctgc atgttcaagt
     2221 gctctccaaa ccccctccat cagcaaccga tgttgaggat ccagaatctc cgcttctttt
     2281 ggagtcatat cgaaaaatga ggcgtcaaaa tcttcaatac catctaattt tccggctgct
     2341 tttacataat ccggatcatt taatgttcga tcatcaactc cggctgctct gagttcatca
     2401 tcactgaaaa aagtaatgga gtctatccca tctcgcagat ttgtccagta ctgattcaag
     2461 gaatcagctc ccgggactcg gatgtgcatc ccgactaccg ctattgtatc ttcgtaatta
     2521 cgcaactttg aattcatggt tgatgcattt gtactcaatc gggggttttt ctgacaaatt
     2581 gatgggtgcc cgagttgaaa ttaatttcat ataaaatcct ttagttatgt gcgattactt
     2641 ttttttgaat ttaactgtgg atcgtttttt tcgaccggca agagaggctg aggctgtttc
     2701 atccatatca tattgcaatg gtgaggggga taaaaagtta gcaagtgccg aaacggtggg
     2761 gtatcggaaa atatcgaccg gtgtaacatc cttattaaat tctttactca atcgatcttt
     2821 cataggtaat accagcatgg agtgtccgcc tatttcaaaa aaattatcat tgatgccaac
     2881 gacatctaca tcaagaaaat cgcaccaaat ctgagcaatt cgttgctcgg aagatccttc
     2941 aacaaagtta ttaatagagt cggattggct aatggatggc tttggtaatg atttatagtc
     3001 tatttttcca tttgaattta atggaatgga ctccaacacc tcaaaatgtg atggaatcat
     3061 gtattcagga agcagttccg acaaatgaag ttgaatatct gctcgattaa attcggcacc
     3121 ggtgtttaaa gtaagatatg ctaccagtcg atcaccttga tcaagatgtt ggatggtaac
     3181 tacggccact ttcactgatt taaaagatgc cagggcgaac tcaatttcag ccggttcaat
     3241 tcgatatccc cgaagtttga attgtgagtc atatcgtccc aaaaaaacca gattactgtc
     3301 cgataacatc ttgacacgat caccggtttg atataatatt ccggttaaaa tcggtttggg
     3361 tccgtgaact aatcctgttt ctgaaacagg tataaatcgc tgttttgtca ggtcatcatg
     3421 attcagatat ccctctgcaa ccccatctcc accaatgtat aattcacctt caacacccgg
     3481 gggtaccggg aatctgtttt gatcaagcac ataaagctgc gtattccaaa taggtttgcc
     3541 aattgggaca ttataggatg aaaactccgt tcttttttca tcataaatgg cacagccgac
     3601 tacggtttct gtgggtccat attcgttaat aatacgtgtt ttaggagcgt gtttacgcca
     3661 cggagcaatt gttttactca ataatgcttc tccacccaat acaaaacttc gtgtgaggcc
     3721 tgattttttg tcatcaggaa tcatagcatt gagcaattca agatgagccg gagtgatttt
     3781 aaccatcgac cagtctgctg ttggtttacc gtttttatca atcaaacatc gtgttatatg
     3841 ttcaatttcg attccatctg tgggtacgat atgaaccgtt cggcctgata ttagcggagt
     3901 aaataaactt gtgatggttg catcaaatgc gatcgaggaa tgtaatggag aaccgatacc
     3961 gtcgcttgtt ttgtaatatt cctgtgccca tgtcagatag ttgagtagtc ctttatgatg
     4021 gattaacgtt cccttgggtt ttccggtcga gcctgacgtg tacatgatat aagcaatatc
     4081 cagtggatca tgctctgttt taaggttctt ttttttcatt tttgcccatt ttgaggcatc
     4141 atcatccatg aaaagcttac ttatcgtact tttatcaata ttttttgaca attcttttgt
     4201 tgtgatgatt aactctggtg aggcatcttc aagcatgtaa gaaattcgtt ccgaaggata
     4261 ctgtttgtcc atcggtatat aagctgctcc cgattttagt acacccatca tagcgataaa
     4321 taactcgggt gaacgatcta aaaatatagc gactcttgaa ctacggccaa ttccattttc
     4381 tgataaccag tgtgccagtt tgttactttg aatattgagt tcatcataca atagattccc
     4441 gtcattccat acaacagcta catccttggc atgttttttt gctaccgatt caaacaattc
     4501 aggtaatgat ttttcagccg gatacgcatg ttcagtcttg ttccacttca ttatccaacg
     4561 tttccactca cgatcattca tcagtgaaat caatcctact tctccatcgg gccgctccat
     4621 gacattccga gccagatttt cgaagtaatc aacaaatctt tcaatactgg aaaccacaaa
     4681 tttatcctcc gaataatcac attccagggt catacgattt ccaacttccg tcagattaaa
     4741 caccagatcg aacgcaacat ggtagacatt ctgtgactcc caattcactt caagttcgtt
     4801 aaatgacgga atatcaccgg gacgatccag gttaaaaatc gattgaatag gcacacctga
     4861 acttgatttt tttgctgcac ccaatttatc aatcaaacga gaaaacgggt aatcctgatg
     4921 ctgatatcca ttgagtaatg tgccacgcat acgtttcaaa tatgtcaaaa atgactcttt
     4981 tggatcatat tttgagcgaa ttggaattaa atgtgtgcaa tatcctataa gattttcgct
     5041 gcctttgagc gacctgccgg caaccggcat cccaacaatg atttccgtct gacccgataa
     5101 ccggtgtaac cataatgtgt acaacgaaaa caaggtcatg aaatgagtag cattgttctt
     5161 ggtgctaaac ttcctgattg tatcaattaa tataggatcc atttcacgcg aaactcgtcc
     5221 ccctttatag gatggtacaa caggtttggg cttatcagcg gggagttcaa gaatgggtaa
     5281 atcaccggac atctcattga gccagtactc ctcttggttt ttaaatgact gaccttcttg
     5341 ccattttaaa tattcctgaa attgcaatgg ctcagaatca gacttacgat cagataagga
     5401 tccgggctcc ttacttaata tttgattata aaaacgagct atttcatgaa tgattaggtt
     5461 cattgagagt ccatcgagca cgatgtgatg tcccttcaat accagatagg aatcagaatc
     5521 actccatttt agcaggtgta cttgcaggag tggacctgtt gataattcga atggtttaca
     5581 tgcatgttct tttaaccata tctggcaagc tttgccggca tctttttctt tagtgaaatt
     5641 cacgattttt agtggaacca ctaatttcgg taatagggtc tgcttttctg tgtctggaac
     5701 aacggtcctc aatgattcat ggcgattaac gacttcctga atggcagaag aaagtgcatc
     5761 cgagtcaaca tggcctttca gcgaaatcag cggactgata tggtaagcca tcgatccctc
     5821 tgtacttatt ccggacaacg ttgctaactg tttttgagct gtgcttaaat caacagtttg
     5881 tggagtggat tgaatttggc tctctttttt tgaagttgga tcgttttttg gtggaataaa
     5941 tccaccgtcg cgcatagcat ttacggattc tttcacaact tcgatgatgc gatcaatatc
     6001 ctgatcggtg tgagctgttg agaggaaaca atttctccat tcccacacaa aaatcccgcg
     6061 aagattcatg tggtagaaca gtaattccag attggtatta aattcaaatc tgaacaaaga
     6121 tccaaaatga gcgacttcga tcgctatttc ttcatccaaa aaccactgat tcaagtgatc
     6181 agccaatttt ttagtcttag cattcagatc aagttgtaat ttagggctgt tctctttgag
     6241 gtgtttcagt gctgctaatg atgccgtcat tgccaatgga tgttggcaga aagtgccgcc
     6301 aaatacaaca cggttgacca atggatacga attgtcacca taatgccagg ctccaccatc
     6361 aattggatcc atcaaatcac tgcgacctgc aaccacacca atcgggagtc caccccccac
     6421 tacttttccg tacgttgcca tatcggcttt tatattaaac catgcctgtg ctcctcccgg
     6481 atgtgtgcgg aatccggtaa tcatttcatc aaaaatgagc aatgcaccaa tttcattggt
     6541 taacgaacgt aatttttgta aaaattcagc aggttgaact ttaggatttc gactttgaac
     6601 aggttcaacc agtacagctg caattgaatc accgtgtttc cggataaact ctaatgaatc
     6661 gggatcatca tataccagaa caaattgatc agcaacagcg cccattggtg ttccgggtga
     6721 gaccggtttg gtcactggaa ttccatcaat ttcctcaacc cgcatcccca taaccgaatc
     6781 agcatgtcca tgccatgctc cttcaaagga tacaattttg tctcgtttag ttgccgctcg
     6841 ggccagtcgc atcgccgcca taaccgcttc tgtgccacta tttgtgaaag taacacgatc
     6901 aaagccggtc atttcgcaga taatttccgc tacttcaccc acatggtcag gtcggggtcc
     6961 catttcgact ccctccaaaa ctatctcttt taatggggtt tcaataaatt cggggtgatg
     7021 tccaaacaaa ctgacaccct gtcccatcgt gatatcgata tattcattcc catccaggtc
     7081 ccatactcta ctgcctcgcg cccggttaga gaccagcggg tataacatct ctttagttga
     7141 aaatctaaaa ccaatcgcag cgcggctatc tgccaaaacg ctccgatatt tttgtgtatg
     7201 tgccttagat ttaccggttt ttgcattgaa ttcccggatc agtttttcaa gatgagcttg
     7261 ctgtgtctcc gtgagtccac gtgcccgaat ttcgagtgga gataacattt tttgaggttg
     7321 aactgcactt tgtgaccggg gttttttcgg ttcctgagcc aattcagcag catttgaaga
     7381 ggttgatccg ggagtggatg aaattccgga gtgaagcctg cttgtgccat cactcttacc
     7441 ggaagtctga tttaaaaaat tcaattggcg ttcaattaac tcattcaaag cagaggatgt
     7501 agcccgaatt tgacttgcaa aaatggcttc cagatcactt tgagatgcag agattggatt
     7561 tgccccggtc catttagggg tatcaacggc atttgaaata gaatctctga tacgattgac
     7621 atctaagccg ggaagatcat cctgtggtct cgaag
//
