LOCUS       c00181_3300022..       13400 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300022888.a:Ga0233428_1003453.
ACCESSION   c00181_3300022..
VERSION     c00181_3300022..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-24 04:08:56
            Original ID  :: 3300022888.a:Ga0233428_1003453
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13400
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13400
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2653:11053](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2654..11053
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..13400
                     /SMILES="NC(C(O)C)C(=O)NCC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13400
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS_motif       2..91
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg181_1_0001"
                     /evalue="8.50E-12"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ctg181_1"
                     /protein_end="30"
                     /protein_start="0"
                     /score="37.1"
                     /tool="antismash"
                     /translation="AMLGVSLGEYVAAVLTGVISLDDGLRIVAQA"
     aSDomain        2..604
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg181_1_PKS_AT.1"
                     /evalue="2.70E-32"
                     /label="ctg181_1_PKS_AT.1"
                     /locus_tag="ctg181_1"
                     /protein_end="201"
                     /protein_start="0"
                     /score="104.0"
                     /specificity="Minowa: trans-1,2-CPDA"
                     /specificity="PKS signature: (unknown)"
                     /specificity="consensus: pk"
                     /tool="antismash"
                     /translation="AMLGVSLGEYVAAVLTGVISLDDGLRIVAQADRFAVNYPMGQTAA
                     VGCGAESLRKRLPSNVYLAVSASPAQSILSGSPQVLEGFCNQLKSEGLAVHPNGANVPF
                     HSPLMREWVDSLAPMLDNIGFDVARTPYVSCVTGNWVTDSDVADPAHYRKIFETEARLE
                     DSIVALKNRFPVERTIFLEAGIGSSIGSFIRQAPSTEER"
     aSModule        2..2572
                     /domains="nrpspksdomains_ctg181_1_PKS_AT.1"
                     /domains="nrpspksdomains_ctg181_1_PKS_KR.1"
                     /domains="nrpspksdomains_ctg181_1_PCP.1"
                     /incomplete
                     /locus_tags="ctg181_1"
                     /tool="antismash"
                     /type="pks"
     CDS             2..2623
                     /NRPS_PKS="Domain: PKS_AT (0-201). E-value: 2.7e-32. Score:
                     104.0. Matches aSDomain: nrpspksdomains_ctg181_1_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_KR (521-701). E-value: 2.3e-37.
                     Score: 120.4. Matches aSDomain:
                     nrpspksdomains_ctg181_1_PKS_KR.1"
                     /NRPS_PKS="Domain: PCP (788-857). E-value: 1.1e-19. Score:
                     62.1. Matches aSDomain: nrpspksdomains_ctg181_1_PCP.1"
                     /NRPS_PKS="type: PKS/NRPS-like protein"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 96.4; E-value: 3e-29)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg181_1"
                     /sec_met_domain="PP-binding (E-value: 9.6e-16, bitscore:
                     46.9, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 3.2e-33, bitscore: 104.0,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="AMLGVSLGEYVAAVLTGVISLDDGLRIVAQADRFAVNYPMGQTAA
                     VGCGAESLRKRLPSNVYLAVSASPAQSILSGSPQVLEGFCNQLKSEGLAVHPNGANVPF
                     HSPLMREWVDSLAPMLDNIGFDVARTPYVSCVTGNWVTDSDVADPAHYRKIFETEARLE
                     DSIVALKNRFPVERTIFLEAGIGSSIGSFIRQAPSTEERLGMFSTAPETWRLDAGRYPQ
                     ALSDHLLSTLGDLWALNAGVDWLGFSRAERLTKVSIPHHPFSKESYWVSSREVQANHAI
                     RDDATKKLPIERWFHVPYWKPNVVKHHEPNKKQFWVLFGDSPLLEVISSFLTDKGVRWE
                     NISDPGSKLLDGKVDTFDLDSSDAWDQLFSVMGVKIPKPDYFVYCPALNSMEKASSFDG
                     RDLRPLIFLGRQLGANYFQEEVTLAVAFESGDDRVSGAVGDVFLGPVRVLPQEFRNIST
                     GLIQVDEPIGVPVPDLGSFLVSDIIGLSGSARYLRTGRVRFDEAYSPISLPPPDGLPSL
                     LRQKGSYLITGGLGHIGMTIARHLLSTADANIVLTTRGRDLPQGQSDLVNQYPGKVLIV
                     RARAENSAEMAQAVAVLEEKFGRLDGVIHAAGLVGDQSFLTIGEAPVGSHLDQFPGKVG
                     GVEVIERLLETRNPDFVFLCSSLSPALGGLGFAAYASANAMLDRYADQHAAQNAPIWVG
                     INWEGWQSPDAIDSGLGDSDILEKELTPEEGCAVFDRIANQANFPRILVSTSDFEQRRS
                     TWVHAATLPSASFEDVQMHPRPEILGRAVAGDSDTEKRLIGIWERLLGIAPLGTTDNFF
                     ELGGNSLILTQFVASARQEFSVDLPLVALFESPRIDVIATTIDHASPERAPVSGSRQRG
                     VI"
     aSDomain        1565..2104
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg181_1_PKS_KR.1"
                     /evalue="2.30E-37"
                     /label="ctg181_1_PKS_KR.1"
                     /locus_tag="ctg181_1"
                     /protein_end="701"
                     /protein_start="521"
                     /score="120.4"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GSYLITGGLGHIGMTIARHLLSTADANIVLTTRGRDLPQGQSDLV
                     NQYPGKVLIVRARAENSAEMAQAVAVLEEKFGRLDGVIHAAGLVGDQSFLTIGEAPVGS
                     HLDQFPGKVGGVEVIERLLETRNPDFVFLCSSLSPALGGLGFAAYASANAMLDRYADQH
                     AAQNAPIWVGINWEGWQS"
     CDS_motif       1568..1663
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg181_1_0002"
                     /evalue="6.70E-11"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg181_1"
                     /protein_end="554"
                     /protein_start="522"
                     /score="34.8"
                     /tool="antismash"
                     /translation="SYLITGGLGHIGMTIARHLLSTADANIVLTTRG"
     CDS_motif       1949..2050
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg181_1_0003"
                     /evalue="3.60E-10"
                     /label="PKSI-KR_m4"
                     /locus_tag="ctg181_1"
                     /protein_end="683"
                     /protein_start="649"
                     /score="32.4"
                     /tool="antismash"
                     /translation="DFVFLCSSLSPALGGLGFAAYASANAMLDRYADQH"
     aSDomain        2366..2572
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg181_1_PCP.1"
                     /evalue="1.10E-19"
                     /label="ctg181_1_PCP.1"
                     /locus_tag="ctg181_1"
                     /protein_end="857"
                     /protein_start="788"
                     /score="62.1"
                     /tool="antismash"
                     /translation="EKRLIGIWERLLGIAPLGTTDNFFELGGNSLILTQFVASARQEFS
                     VDLPLVALFESPRIDVIATTIDHAS"
     CDS             2654..11053
                     /NRPS_PKS="Domain: Condensation_LCL (74-370). E-value:
                     9.5e-94. Score: 305.4. Matches aSDomain:
                     nrpspksdomains_ctg181_2_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (533-939). E-value: 6.1e-98.
                     Score: 319.8. Matches aSDomain:
                     nrpspksdomains_ctg181_2_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1054-1119). E-value: 3.2e-12.
                     Score: 38.2. Matches aSDomain:
                     nrpspksdomains_ctg181_2_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1464-1762). E-value:
                     1.7e-96. Score: 314.5. Matches aSDomain:
                     nrpspksdomains_ctg181_2_Condensation_LCL.2"
                     /NRPS_PKS="Domain: AMP-binding (1932-2323). E-value:
                     1.1e-89. Score: 292.6. Matches aSDomain:
                     nrpspksdomains_ctg181_2_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2442-2510). E-value: 2.8e-21.
                     Score: 67.3. Matches aSDomain:
                     nrpspksdomains_ctg181_2_PCP.2"
                     /NRPS_PKS="Domain: Thioesterase (2531-2793). E-value:
                     8.4e-29. Score: 93.3. Matches aSDomain:
                     nrpspksdomains_ctg181_2_Thioesterase.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     361.8; E-value: 1e-109)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg181_2"
                     /sec_met_domain="Condensation (E-value: 6.9e-72, bitscore:
                     230.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.6e-104, bitscore:
                     338.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6.9e-17, bitscore:
                     50.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1e-12, bitscore:
                     37.8, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 8.9e-09, bitscore: 24.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSTATLLAMLKQRDIRLSLVEDQLQYDAPDGAMSESLIEEVRKR
                     KSELIEHLSGNIDQAPFSQSPLVCRASGATVPLSSDQRRLWFLDLLERGNSYAYNMPPV
                     VLKLTGVLDTKALENAFSEMVRRHEVLRTSFDSDDTGPFQVVHPHYQVRIPIEDTVGKD
                     YETKVHDEASYPFSLASGEPLFRVRLFRVDVEEYVFCLTIHHIVCDGWSIGILVRELSN
                     LYSAMVVGKVLVLPELPVQYGDFSIWQESQLKPPGFDAARRFWRDALRELPRSLDLPTD
                     LVRQGAPDFRGVTEYHLLPGSLTNRIKQYCTSHHLTEFMLLLTAFYLLLVRFTGNRDIV
                     VGTPVSVRPDPLLEQLIGLFLNTVPIRIDISNQESTSSITQIVKQAFLNAFEYRELPLE
                     EIIREATIDRGIGQSTLFRTLFALQNAPLNEVQLEKLKISPLPTVNVNSVLDLVMSIEE
                     NGNGFEIKLRGASQLFERVTLKMLVQQYEQIVEGLLGGSTLVDNLGVKPSAFPANAAVG
                     QQHFYIDESIFGRLRTIAGKDPDKVALISGDVRLSYRKLLSQVEHLSHTIAPYVAEPGT
                     PIAIFASRTADLVVSILAVLRAGGAYVPLDPDSPSDRIGFILKDSGATAVVIDRHAGAL
                     PDVPQDIHQIDLVNVSINACETAIKKLPPQPEDIAYVIYTSGSTGEPKGVRVSHSNVLR
                     LIDSTSGLFDFNSKDVWTLFHSPAFDFSVWEIFGALLNGACLLVVPWATSRDPARFYRF
                     VLDNQVTVLNQTPSAFKLFENQDTRSTADLALRWIIFGGEALNFNSVLGWSKRHGLNSP
                     GLVNMYGITETTVHTTYRRIVSDDLDSPRKSRIGRPLPDLGIVIVDRQMNPVSRGAIGE
                     IVVSGAGVSHGYHARPELNAEKFPLASEFPSLVGLGISGRIYRSGDLGRWTAADDLEYC
                     GRLDDQIKIHGYRLEPGEIEAVIKTNPEVKDVLVTTFEDRQEISSLVAYLVWQGDAEGD
                     LGQIKRLLLSKLPRYMCPSKFLVLKEFPLNINGKIDRGALPFPDEAAPQVETGEELLPN
                     ELDHQRIVRKAWIDVIGIDAINSGDNFFELGGDSVRAALVVNILQEAFEEVLYVAGIFE
                     HPVLQDYCEHLETEYEIAKPKPRKSVGVQSKDFEKFDKIARSVCSSVAVGSTKNPRAIF
                     ILSPPRSGSTLLRVLLGGHPGLFSPPELELLRFGTIKERANEFSGPISFYLEGLIRALM
                     ELNHWSVEQATERVKQLEADGCSAQQMFQHLQEMAKGRILVDKTPSYSLDINALMRIEQ
                     MFEQPLYIHLYRHPCGMIRSFVNAHLDQIFFRHDHCLEASALGELIWNRSHQNIRKTLH
                     NIPSTRKILVNFEALTRQTRHELERVCEFLDLPFDQRMLDLYSDSSGRMTDGVRQESRM
                     IGDVRFHQHKKIEEDVGSAWEDQMRFEELSEDTQHVWSNLRSSEGEKLPDSNEDLGGCS
                     QTSWHPSLSQERIWFLDQLDDSSRAYTIPGAMMLDGALNETAFNNAVLRLTERHVVLNS
                     RFMKVEGEVRVDVSQSHQGVTWGDVSKVERTDREEAISAFVSENAKHQFDLSQGGLFRV
                     EIVRVDERRFLLLVNLHHIVCDGWSLDILFSELSALYNAEVDGCRDGLSPLSVSFGDYA
                     NWQREQATNNRVKKQLTYWREQLSGLPPALELPTDFLRKSVQTFNGDRVQVSLDTEVSN
                     NIRKYCNDRGCTVFMYLLANFALLLGRITGSEDIPIGTPTSARPRKEFEGLVGFFANTL
                     VLRLRLGQVGFDEVLAATRQTCLDALSNQDISFEQLVSAVQPDRNLSVSPIFQVMFSLQ
                     RKSSTTLRFSTIKATPIETSIDSTKYDLSLLLEDHDSTIKGCFEFNRDLFANQRIEFLS
                     DQFVNLVKRNLCHESTISTSVNYYGAAENAFLARFGQGKVTTMPVPQLVGQWIDIGIKR
                     SPGDAVAVRFQGQSLTYTELGLEVETAALCLRNLGIGAGDRVGVCYRRDLHLVPWLLGI
                     LNIGACYVPLDPALPDERLDFILVDSDLSKVLCSEEYAGRSCFKEITTFHRELSGAQDK
                     ASRSVATDVSEQSAAYICYTSGSTGIPKGVPVSHRSVVNLLTAMQKLLRLTPSDKWVAI
                     TTLSFDIHVPELLLPLGVGGQVCLASESEARDPRQLINLLATHKATVLQATPSTWHSIE
                     VAGWEGEPGLRALSGGEALSRDLATSLLPKVDSLWNMYGPTETTVWSSAQQVTKEELLI
                     RNSVAIGRPLLNTTFYVVDKTRRALPVGAWGELAIGGEGVCDGYLNRPDLAVGRFVTLP
                     DFDSQSRAYLTGDRVRLTESGIFEVSGRFDNQIKVRGVRVEPEEIEAVLEKHPEVLRAV
                     VVLKELTQNEKILIGVIAVEPPHRKSVTQEVLRFAEKILPATMVPGRLVCLEELPITPN
                     GKVDRGRILPILDQDEADLIDDPSIETNIATVGRDVIELKLVSLWRKYLGVPNIRVDDN
                     FFSVGGHSLLAVRLIAAVEKEFKQQLPLAALFEMPTVRLMAEKLRADGGMSELWSRPIE
                     LRTGSEHLTLFLVPGAGGNVLYFQELAKNCPVGVRVVALQPPGLDGVHPPVGTIEGLAD
                     LFLDQIQEQLHEEMDKVVVIGHSFGGLVAYEMACRAHTKSMVIDSLFIIDTAAPNLAES
                     TGRDWSHEEWICHLSQIAGYMFDVDVEVFQQEVAGLNDISQIEVFHHKLVDAGVIAVGV
                     SAQFVSGLVNVYRSNLCAEPPQGLLPNEDMAPTIIRSLQEQPGHLSDETSRRNRLHGDL
                     GWEEYLGYPVKVIDAPGDHLTMLQDSNAGVLAKIICGKVF"
     aSDomain        2876..3763
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg181_2_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="9.50E-94"
                     /label="ctg181_2_Condensation_LCL.1"
                     /locus_tag="ctg181_2"
                     /protein_end="370"
                     /protein_start="74"
                     /score="305.4"
                     /tool="antismash"
                     /translation="TVPLSSDQRRLWFLDLLERGNSYAYNMPPVVLKLTGVLDTKALEN
                     AFSEMVRRHEVLRTSFDSDDTGPFQVVHPHYQVRIPIEDTVGKDYETKVHDEASYPFSL
                     ASGEPLFRVRLFRVDVEEYVFCLTIHHIVCDGWSIGILVRELSNLYSAMVVGKVLVLPE
                     LPVQYGDFSIWQESQLKPPGFDAARRFWRDALRELPRSLDLPTDLVRQGAPDFRGVTEY
                     HLLPGSLTNRIKQYCTSHHLTEFMLLLTAFYLLLVRFTGNRDIVVGTPVSVRPDPLLEQ
                     LIGLFLNTVPIRIDIS"
     aSModule        2876..6010
                     /complete
                     /domains="nrpspksdomains_ctg181_2_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg181_2_AMP-binding.1"
                     /domains="nrpspksdomains_ctg181_2_PCP.1"
                     /locus_tags="ctg181_2"
                     /monomer_pairings="thr -> thr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       2888..2920
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg181_2_0001"
                     /evalue="1.90E-01"
                     /label="C1_LCL_004-017"
                     /locus_tag="ctg181_2"
                     /protein_end="89"
                     /protein_start="78"
                     /score="5.2"
                     /tool="antismash"
                     /translation="SSDQRRLWFLDL"
     CDS_motif       2945..3058
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg181_2_0002"
                     /evalue="6.40E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg181_2"
                     /protein_end="135"
                     /protein_start="97"
                     /score="47.5"
                     /tool="antismash"
                     /translation="AYNMPPVVLKLTGVLDTKALENAFSEMVRRHEVLRTSFD"
     CDS_motif       3260..3325
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg181_2_0003"
                     /evalue="3.70E-12"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg181_2"
                     /protein_end="224"
                     /protein_start="202"
                     /score="38.6"
                     /tool="antismash"
                     /translation="IHHIVCDGWSIGILVRELSNLYS"
     CDS_motif       3374..3412
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg181_2_0004"
                     /evalue="9.80E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg181_2"
                     /protein_end="253"
                     /protein_start="240"
                     /score="11.9"
                     /tool="antismash"
                     /translation="QYGDFSIWQESQLK"
     CDS_motif       3665..3754
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg181_2_0005"
                     /evalue="1.00E-12"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg181_2"
                     /protein_end="367"
                     /protein_start="337"
                     /score="40.4"
                     /tool="antismash"
                     /translation="DIVVGTPVSVRPDPLLEQLIGLFLNTVPIRI"
     CDS_motif       3803..3922
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg181_2_0006"
                     /evalue="5.40E-05"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg181_2"
                     /protein_end="423"
                     /protein_start="383"
                     /score="15.5"
                     /tool="antismash"
                     /translation="KQAFLNAFEYRELPLEEIIREATIDRGIGQSTLFRTLFALQ"
     aSDomain        4253..5470
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg181_2_AMP-binding.1"
                     /evalue="6.10E-98"
                     /label="ctg181_2_AMP-binding.1"
                     /locus_tag="ctg181_2"
                     /protein_end="939"
                     /protein_start="533"
                     /score="319.8"
                     /specificity="consensus: thr"
                     /tool="antismash"
                     /translation="IAGKDPDKVALISGDVRLSYRKLLSQVEHLSHTIAPYVAEPGTPI
                     AIFASRTADLVVSILAVLRAGGAYVPLDPDSPSDRIGFILKDSGATAVVIDRHAGALPD
                     VPQDIHQIDLVNVSINACETAIKKLPPQPEDIAYVIYTSGSTGEPKGVRVSHSNVLRLI
                     DSTSGLFDFNSKDVWTLFHSPAFDFSVWEIFGALLNGACLLVVPWATSRDPARFYRFVL
                     DNQVTVLNQTPSAFKLFENQDTRSTADLALRWIIFGGEALNFNSVLGWSKRHGLNSPGL
                     VNMYGITETTVHTTYRRIVSDDLDSPRKSRIGRPLPDLGIVIVDRQMNPVSRGAIGEIV
                     VSGAGVSHGYHARPELNAEKFPLASEFPSLVGLGISGRIYRSGDLGRWTAADDLEYCGR
                     LDDQIKIH"
     CDS_motif       4430..4471
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg181_2_0007"
                     /evalue="2.20E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg181_2"
                     /protein_end="606"
                     /protein_start="592"
                     /score="17.6"
                     /tool="antismash"
                     /translation="LAVLRAGGAYVPLDP"
     CDS_motif       4661..4720
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg181_2_0008"
                     /evalue="6.20E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg181_2"
                     /protein_end="689"
                     /protein_start="669"
                     /score="31.0"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGEPKGVRVSHS"
     CDS_motif       5105..5134
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg181_2_0009"
                     /evalue="1.30E+00"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg181_2"
                     /protein_end="827"
                     /protein_start="817"
                     /score="2.8"
                     /tool="antismash"
                     /translation="YGITETTVHTT"
     CDS_motif       5252..5335
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg181_2_0010"
                     /evalue="5.10E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg181_2"
                     /protein_end="894"
                     /protein_start="866"
                     /score="38.0"
                     /tool="antismash"
                     /translation="GAIGEIVVSGAGVSHGYHARPELNAEKFP"
     CDS_motif       5438..5503
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg181_2_0011"
                     /evalue="4.10E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg181_2"
                     /protein_end="950"
                     /protein_start="928"
                     /score="31.8"
                     /tool="antismash"
                     /translation="YCGRLDDQIKIHGYRLEPGEIEA"
     aSDomain        5816..6010
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg181_2_PCP.1"
                     /evalue="3.20E-12"
                     /label="ctg181_2_PCP.1"
                     /locus_tag="ctg181_2"
                     /protein_end="1119"
                     /protein_start="1054"
                     /score="38.2"
                     /tool="antismash"
                     /translation="IVRKAWIDVIGIDAINSGDNFFELGGDSVRAALVVNILQEAFEEV
                     LYVAGIFEHPVLQDYCEHLET"
     CDS_motif       6386..6421
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg181_2_0012"
                     /evalue="2.70E+01"
                     /label="C3_starter_134-155"
                     /locus_tag="ctg181_2"
                     /protein_end="1256"
                     /protein_start="1244"
                     /score="-1.8"
                     /tool="antismash"
                     /translation="DGCSAQQMFQHLQ"
     aSDomain        7046..7939
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg181_2_Condensation_LCL.2"
                     /domain_subtype="Condensation_LCL"
                     /evalue="1.70E-96"
                     /label="ctg181_2_Condensation_LCL.2"
                     /locus_tag="ctg181_2"
                     /protein_end="1762"
                     /protein_start="1464"
                     /score="314.5"
                     /tool="antismash"
                     /translation="WHPSLSQERIWFLDQLDDSSRAYTIPGAMMLDGALNETAFNNAVL
                     RLTERHVVLNSRFMKVEGEVRVDVSQSHQGVTWGDVSKVERTDREEAISAFVSENAKHQ
                     FDLSQGGLFRVEIVRVDERRFLLLVNLHHIVCDGWSLDILFSELSALYNAEVDGCRDGL
                     SPLSVSFGDYANWQREQATNNRVKKQLTYWREQLSGLPPALELPTDFLRKSVQTFNGDR
                     VQVSLDTEVSNNIRKYCNDRGCTVFMYLLANFALLLGRITGSEDIPIGTPTSARPRKEF
                     EGLVGFFANTLVLRLRLG"
     aSModule        7046..11032
                     /complete
                     /domains="nrpspksdomains_ctg181_2_Condensation_LCL.2"
                     /domains="nrpspksdomains_ctg181_2_AMP-binding.2"
                     /domains="nrpspksdomains_ctg181_2_PCP.2"
                     /domains="nrpspksdomains_ctg181_2_Thioesterase.1"
                     /final_module
                     /locus_tags="ctg181_2"
                     /monomer_pairings="gly -> gly"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       7055..7087
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg181_2_0013"
                     /evalue="2.20E-01"
                     /label="C1_LCL_004-017"
                     /locus_tag="ctg181_2"
                     /protein_end="1478"
                     /protein_start="1467"
                     /score="5.0"
                     /tool="antismash"
                     /translation="SLSQERIWFLDQ"
     CDS_motif       7109..7219
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg181_2_0014"
                     /evalue="3.50E-07"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg181_2"
                     /protein_end="1522"
                     /protein_start="1485"
                     /score="22.7"
                     /tool="antismash"
                     /translation="AYTIPGAMMLDGALNETAFNNAVLRLTERHVVLNSRFM"
     CDS_motif       7436..7501
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg181_2_0015"
                     /evalue="1.70E-11"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg181_2"
                     /protein_end="1616"
                     /protein_start="1594"
                     /score="36.5"
                     /tool="antismash"
                     /translation="LHHIVCDGWSLDILFSELSALYN"
     CDS_motif       7553..7585
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg181_2_0016"
                     /evalue="7.70E-03"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg181_2"
                     /protein_end="1644"
                     /protein_start="1633"
                     /score="9.2"
                     /tool="antismash"
                     /translation="FGDYANWQREQA"
     CDS_motif       7841..7930
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg181_2_0017"
                     /evalue="5.40E-15"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg181_2"
                     /protein_end="1759"
                     /protein_start="1729"
                     /score="47.7"
                     /tool="antismash"
                     /translation="DIPIGTPTSARPRKEFEGLVGFFANTLVLRL"
     CDS_motif       7976..8095
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg181_2_0018"
                     /evalue="2.60E-20"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg181_2"
                     /protein_end="1814"
                     /protein_start="1774"
                     /score="64.8"
                     /tool="antismash"
                     /translation="RQTCLDALSNQDISFEQLVSAVQPDRNLSVSPIFQVMFSLQ"
     aSDomain        8450..9622
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg181_2_AMP-binding.2"
                     /evalue="1.10E-89"
                     /label="ctg181_2_AMP-binding.2"
                     /locus_tag="ctg181_2"
                     /protein_end="2323"
                     /protein_start="1932"
                     /score="292.6"
                     /specificity="consensus: gly"
                     /tool="antismash"
                     /translation="RSPGDAVAVRFQGQSLTYTELGLEVETAALCLRNLGIGAGDRVGV
                     CYRRDLHLVPWLLGILNIGACYVPLDPALPDERLDFILVDSDLSKVLCSEEYAGRSCFK
                     EITTFHRELSGAQDKASRSVATDVSEQSAAYICYTSGSTGIPKGVPVSHRSVVNLLTAM
                     QKLLRLTPSDKWVAITTLSFDIHVPELLLPLGVGGQVCLASESEARDPRQLINLLATHK
                     ATVLQATPSTWHSIEVAGWEGEPGLRALSGGEALSRDLATSLLPKVDSLWNMYGPTETT
                     VWSSAQQVTKEELLIRNSVAIGRPLLNTTFYVVDKTRRALPVGAWGELAIGGEGVCDGY
                     LNRPDLAVGRFVTLPDFDSQSRAYLTGDRVRLTESGIFEVSGRFDNQIKVRG"
     CDS_motif       8621..8662
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg181_2_0019"
                     /evalue="4.80E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg181_2"
                     /protein_end="2003"
                     /protein_start="1989"
                     /score="10.6"
                     /tool="antismash"
                     /translation="LGILNIGACYVPLDP"
     CDS_motif       8849..8908
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg181_2_0020"
                     /evalue="5.20E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg181_2"
                     /protein_end="2085"
                     /protein_start="2065"
                     /score="25.1"
                     /tool="antismash"
                     /translation="AYICYTSGSTGIPKGVPVSHR"
     CDS_motif       9272..9295
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg181_2_0021"
                     /evalue="9.00E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg181_2"
                     /protein_end="2214"
                     /protein_start="2206"
                     /score="6.1"
                     /tool="antismash"
                     /translation="YGPTETTVW"
     CDS_motif       9413..9502
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg181_2_0022"
                     /evalue="6.20E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg181_2"
                     /protein_end="2283"
                     /protein_start="2253"
                     /score="34.5"
                     /tool="antismash"
                     /translation="PVGAWGELAIGGEGVCDGYLNRPDLAVGRFV"
     CDS_motif       9593..9652
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg181_2_0023"
                     /evalue="3.40E-08"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg181_2"
                     /protein_end="2333"
                     /protein_start="2313"
                     /score="25.8"
                     /tool="antismash"
                     /translation="GRFDNQIKVRGVRVEPEEIEA"
     aSDomain        9980..10183
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg181_2_PCP.2"
                     /evalue="2.80E-21"
                     /label="ctg181_2_PCP.2"
                     /locus_tag="ctg181_2"
                     /protein_end="2510"
                     /protein_start="2442"
                     /score="67.3"
                     /tool="antismash"
                     /translation="ELKLVSLWRKYLGVPNIRVDDNFFSVGGHSLLAVRLIAAVEKEFK
                     QQLPLAALFEMPTVRLMAEKLRAD"
     aSDomain        10247..11032
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg181_2_Thioesterase.1"
                     /evalue="8.40E-29"
                     /label="ctg181_2_Thioesterase.1"
                     /locus_tag="ctg181_2"
                     /protein_end="2793"
                     /protein_start="2531"
                     /score="93.3"
                     /tool="antismash"
                     /translation="TLFLVPGAGGNVLYFQELAKNCPVGVRVVALQPPGLDGVHPPVGT
                     IEGLADLFLDQIQEQLHEEMDKVVVIGHSFGGLVAYEMACRAHTKSMVIDSLFIIDTAA
                     PNLAESTGRDWSHEEWICHLSQIAGYMFDVDVEVFQQEVAGLNDISQIEVFHHKLVDAG
                     VIAVGVSAQFVSGLVNVYRSNLCAEPPQGLLPNEDMAPTIIRSLQEQPGHLSDETSRRN
                     RLHGDLGWEEYLGYPVKVIDAPGDHLTMLQDSNAGVLAKII"
     CDS_motif       10451..10504
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg181_2_0024"
                     /evalue="9.40E-08"
                     /label="NRPS-te1"
                     /locus_tag="ctg181_2"
                     /protein_end="2617"
                     /protein_start="2599"
                     /score="24.5"
                     /tool="antismash"
                     /translation="VVIGHSFGGLVAYEMACRA"
     CDS             11079..12098
                     /locus_tag="ctg181_3"
                     /transl_table=11
                     /translation="MMRNYALSLLFTLLGLFSAVVQAAQVADKNFHPQVATPAFSKGSG
                     PVVAVDAAHANFHTCEGRYIAFCELLGNDGYRIKTNNDSFSMENLNTIDLLVIANALNK
                     KNIDPKQNWATPILPAFTEKETQNLVKWVKSGGALLVIADHMPFPGAVSDLGLKFGVNW
                     GNSYAFAADTQIVEAAKKNTLSVIKGPDANMMTFDLKGLNSTGVQAYPHPIFHGRNPTE
                     NVPFITTFTGSAFTLLPGSQVNPLMGLGEGTLLMFPLKSQEQSLMTPRGPGAGTLQGGV
                     LEFGKGRVAIMGEASMFSAQIADYISPGFKMGMNNTEHAPHNVQFALNLTHWLTKINN"
     CDS             12130..12324
                     /locus_tag="ctg181_4"
                     /transl_table=11
                     /translation="VEKEPSVNESENKSVVERIQRLEKTTKIMLGLAVGAVAISVVGAA
                     LLPLKLKVALPKLGIKVLS"
     CDS             complement(12365..12847)
                     /locus_tag="ctg181_5"
                     /transl_table=11
                     /translation="LIKIAQKTYQLSKQPKSSDVVTLFSCPDKFIKAFTPDLPKFIRLQ
                     KIAVEPTSVKAAFTSLVPIELDAKIDSTVGSRSGEVECQINFNFRGGSRAKDRIFLNIR
                     TLRMTLVFSARKNQLSVVLQYTKGEKPSPALLHYKALAVLTRQARPLAQAVNHHLP"
     CDS             12887..13084
                     /locus_tag="ctg181_6"
                     /transl_table=11
                     /translation="VNVASSLAKPCNWKTNLDETVLLHITVTRPTAALGSYPGDVLAGI
                     LDIAGLAVDTVLGVYLEALV"
ORIGIN
        1 ggctatgctt ggggtgagct tgggggaata tgtcgccgct gttttaaccg gtgtgatttc
       61 tcttgatgat ggtttgcgca ttgtcgccca ggccgatcgc ttcgcggtga attatccgat
      121 gggccaaacg gcggcagtag gttgtggcgc agagtcgctt cgtaaacgac tcccctcgaa
      181 cgtctatctt gcggtatcgg catcgccggc tcaatcaatc ctatctgggt caccccaggt
      241 ccttgaaggt ttttgcaatc aactgaaatc agaggggctg gctgttcatc caaacggggc
      301 taatgtgccc tttcattcgc ctctgatgag agagtgggtc gatagtttgg caccgatgtt
      361 ggacaacatt ggttttgatg tcgcccggac cccttacgtg tcgtgcgtaa ctggaaactg
      421 ggttaccgat tccgacgttg ccgatccggc tcattatcga aagatatttg aaacagaggc
      481 gcgactggaa gatagcattg tagccttaaa aaatcgcttt ccggtcgagc gtactatatt
      541 ccttgaagca ggaattggct cgtcaatagg gtcatttatt cgacaggcgc caagtacgga
      601 agaacgtctc ggcatgttct caaccgcacc tgaaacgtgg cggctggatg ctggtcgata
      661 tcctcaagcc ctcagtgatc atctgctttc aacgcttgga gatttgtggg ctcttaatgc
      721 aggtgtagat tggctgggtt tttcccgagc cgaaagactc actaaggtat caattccaca
      781 ccacccgttc agtaaagaaa gttactgggt atcgtcccgt gaggtccagg caaatcatgc
      841 aatccgggat gacgcgacaa aaaaactacc tattgagcga tggtttcatg tgccgtattg
      901 gaagcccaat gttgtcaagc accatgaacc gaataaaaaa cagttctggg ttctttttgg
      961 agattcccct cttttggagg tcatctctag tttcttaacg gataaaggag ttcgatggga
     1021 gaatatttct gaccctggtt ccaagttgct ggatggaaaa gtggatacgt tcgacctaga
     1081 cagttctgat gcatgggatc aacttttttc ggtaatgggg gtaaagattc cgaaaccgga
     1141 ttattttgtt tattgcccag cactgaacag tatggagaag gcctcctcct ttgatggaag
     1201 ggacctacga ccgttgattt ttctaggacg tcagttggga gcgaattatt tccaggagga
     1261 ggttactctg gcagttgcgt ttgagtcggg tgatgatcgg gtttctgggg cagtcggcga
     1321 tgtgtttctt ggacctgtgc gggttttgcc tcaggaattc cgaaatatca gcactggtct
     1381 gatacaagtt gacgaaccga ttggagtgcc tgtccctgac ctgggtagtt ttctggtttc
     1441 agacattatt ggtctgagcg gttccgcccg ttacctgcgc acaggtcgag tacgatttga
     1501 cgaggcatat tccccaattt ctttgccccc cccagatggc ctgccttcgc tattgcggca
     1561 aaaggggtcc tatttgatca ccggtggcct gggccatatc ggtatgacaa ttgctcggca
     1621 tcttctttcg acagctgatg cgaacatcgt gctgacgaca cgtgggcggg atcttccgca
     1681 gggccagtca gatttagtaa atcagtatcc cgggaaggta ttaatagtcc gtgcccgagc
     1741 agaaaactcc gctgaaatgg cacaggcggt agcagttctt gaagaaaaat tcgggcgact
     1801 cgatggcgta atccatgcag ccggactggt aggggatcaa tctttcctaa cgatcggcga
     1861 ggcgccggtc gggtcccacc ttgatcagtt cccaggcaag gtaggtggtg tcgaagtaat
     1921 tgagcgcctt ttggaaactc gtaatccgga tttcgttttc ctttgttcgt ctctttctcc
     1981 cgcgctcgga ggcctagggt ttgcggctta tgcttcggct aatgcaatgc ttgaccgtta
     2041 tgcagaccaa cacgctgccc aaaacgctcc aatctgggtg ggcattaact gggagggttg
     2101 gcagagtcct gacgctattg attctggcct tggagattca gatattttgg aaaaagagtt
     2161 gacaccggaa gaaggttgcg cagtttttga tcgaatagcc aatcaagcta atttccctcg
     2221 gattcttgta tcgacctccg actttgagca aagacgaagt acatgggtgc atgcggccac
     2281 actgccatcg gcctctttcg aggatgttca gatgcaccct cgcccggaaa ttcttggtcg
     2341 ggcggttgct ggagatagtg acaccgagaa aaggctgata ggtatctggg agcgcctgct
     2401 tgggattgct cctctgggaa cgaccgataa tttctttgaa ctgggtggga attcactgat
     2461 tctcacccag tttgtggcca gtgcgaggca ggagttttcc gtggacctcc cgttggtagc
     2521 gctttttgag agtcccagaa ttgacgtcat tgcgacgacg attgatcacg cgtcgcctga
     2581 gcgcgcgcct gtttcgggct cacggcagcg cggtgttatc taagtcgcta atgctagcca
     2641 ctcggccact cgtatgagca gtacagcgac actcctcgcg atgctcaagc agcgcgacat
     2701 tcgtctttca ttagtggagg atcaactcca atatgatgcg ccagacggcg ccatgtcgga
     2761 gtctttgatc gaagaagtcc gaaaacgcaa aagtgaactt attgaacacc tgtcggggaa
     2821 catagaccag gctcctttta gccaatctcc attggtctgt cgagcaagcg gtgcgactgt
     2881 tccactctca agtgatcaac gtcgattgtg gtttcttgac ttgctcgagc gtggaaattc
     2941 ctatgcctac aacatgccac ctgtagtttt aaagctaacc ggtgttcttg atactaaggc
     3001 tttggaaaat gcattctccg aaatggttcg caggcatgaa gtattgcgaa cttcattcga
     3061 cagtgacgac acggggccgt ttcaagttgt acatccacat tatcaggtgc ggataccaat
     3121 agaagacact gtgggcaagg actacgagac aaaggtacat gatgaagcct cttacccttt
     3181 ttcacttgcg agcggggaac cactttttcg tgtccgtttg ttccgagtcg acgttgagga
     3241 gtatgtattc tgcttgacga tccatcacat cgtatgtgac ggctggagca tcggtattct
     3301 cgtcagagag ttatcgaacc tctattctgc aatggtcgtt ggtaaggtac tggtcttacc
     3361 tgagttgccg gttcaatacg gtgacttttc gatttggcag gagtcgcaac ttaagccacc
     3421 tggtttcgat gcggcacgta ggttctggcg tgatgcgctt agagaactgc caaggtctct
     3481 tgaccttcca acagaccttg ttcggcaagg cgcgcctgat ttccgtgggg taacggagta
     3541 tcaccttctg cctggttcgt tgacaaatag gatcaaacaa tattgtacgt cgcaccatct
     3601 tacagaattc atgcttctct tgacggcatt ttatttgctt ctggtgagat tcactggaaa
     3661 cagggatatc gttgttggca caccggtatc agtaaggccc gatccattac tggaacaact
     3721 tattgggctt ttccttaata ccgtaccgat acggatagat atctccaacc aggagtcgac
     3781 aagctcgatt acacagatcg taaaacaagc ctttctaaac gcatttgagt accgagagct
     3841 tccgctcgag gagatcatcc gagaggcaac cattgataga ggtattggcc agtcaacatt
     3901 atttcgcaca ttgtttgctc tgcagaacgc accactaaat gaggttcaac ttgagaagct
     3961 caaaatctcg ccactgccta ccgttaatgt caattcagtt ctcgatttag tgatgtccat
     4021 tgaggagaat ggcaatggat ttgagatcaa acttcgtggg gcaagccagc tatttgagcg
     4081 agtaaccctg aaaatgcttg ttcagcaata cgaacagata gttgagggac ttcttggcgg
     4141 gtcgacgttg gtagataacc ttggggtcaa gccatccgcc tttcctgcaa acgcagcggt
     4201 aggacagcag catttttata tcgacgaatc tatctttggt aggttaagaa caatagcggg
     4261 gaaagaccct gacaaggtag cgctaatttc gggagatgtt cgactatcat atcgaaagct
     4321 ccttagccaa gttgagcatc tcagccacac gatagccccc tatgtagcag aacccgggac
     4381 gcctatcgct atttttgcct ctcgcacggc tgacctagtc gtatcaattc tagctgtcct
     4441 aagagcaggt ggtgcctatg ttccgctcga cccggacagt ccatctgatc gaatcgggtt
     4501 tattcttaaa gattctgggg ccacggcagt tgtgatcgac cgtcatgcag gcgccttgcc
     4561 agacgtacct caagatatcc accaaattga tctagttaat gtgtcaatca atgcctgtga
     4621 gacagcgatc aaaaaattgc cgcctcagcc tgaagatatt gcatatgtaa tttatacatc
     4681 tggctcaact ggagagccaa aaggggtgcg ggttagtcac tcgaatgtgt tgcggttaat
     4741 cgactcgacg tcgggcttgt tcgactttaa ctctaaagat gtttggactt tgtttcattc
     4801 gccagcgttt gatttttcag tttgggagat ttttggcgcc ttactaaacg gtgcctgcct
     4861 gctcgttgtt ccttgggcca ctagtcgaga tccagctcgc ttctatcgtt ttgtattaga
     4921 taatcaagtg acagtcctta atcaaacgcc atctgcattt aagttattcg aaaaccagga
     4981 tactagatcc acggcagacc tcgcactcag atggattatt ttcggtgggg aggcgctaaa
     5041 tttcaattca gtcttgggat ggtcaaaacg ccatggattg aattcgcctg ggctcgtcaa
     5101 tatgtatggc attaccgaga ctacagtcca cacgacctat cggcgtattg tttccgatga
     5161 cttggacagt cctcgcaaaa gccgaatagg tagaccgctt cccgatttag gcatcgtgat
     5221 cgttgatcgg caaatgaacc ccgtcagccg tggtgcaatt ggcgagatcg tagtcagtgg
     5281 ggcaggggtt tcccatggct atcatgctcg gcccgagctc aatgctgaaa aatttcccct
     5341 agcatcggaa tttccctctt tagttgggtt gggtatttcg gggcggattt accgctcagg
     5401 agacttaggc cgatggaccg cggccgatga ccttgagtac tgtggtcggt tggatgacca
     5461 gatcaagata catggatacc ggctcgaacc tggcgagata gaggcagtga tcaaaaccaa
     5521 tccggaagta aaagatgtac tggtcacgac tttcgaagat cggcaggaaa tcagttcctt
     5581 agtagcctac ttagtctggc aaggggatgc ggaaggggat ctcggtcaga ttaaacgctt
     5641 actactttct aaattgccaa gatatatgtg cccgagtaaa ttcctcgttc taaaggaatt
     5701 tcctttgaat atcaatggca aaattgatcg aggcgccctt ccttttccgg atgaggctgc
     5761 ccctcaggtc gaaaccggcg aagagttgct gccgaacgag ttggatcatc agcgaatcgt
     5821 gcgcaaggcg tggatcgatg tgatcggtat agatgccatt aattcgggag ataacttttt
     5881 tgagcttggc ggggactccg ttcgtgcagc tctggtggtg aatattttgc aagaagcgtt
     5941 tgaggaggtt ttatatgttg cgggcatatt cgagcacccg gtcttgcaag actattgtga
     6001 acaccttgag accgaatatg aaatcgcgaa gccgaagcct agaaaaagtg ttggtgttca
     6061 aagtaaagat tttgagaagt tcgacaagat tgccagatcc gtatgctcaa gtgttgcagt
     6121 cggatctacg aagaatccgc gcgcgatctt cattttatcg ccgccgcggt cggggtcaac
     6181 acttctgcga gttctcctcg gcgggcatcc agggttattt tcgccgcccg aactcgaact
     6241 gcttcgcttt gggaccataa aggaacgtgc caatgaattt tcgggaccca tatcgtttta
     6301 tcttgagggc ttgattcgcg cccttatgga gttgaatcat tggtcagtcg aacaggctac
     6361 tgaaagggtt aaacaactcg aggcagacgg gtgcagtgcg cagcaaatgt tccaacactt
     6421 gcaggaaatg gccaaaggcc gaattctggt agataaaacc ccctcctaca gtttagatat
     6481 caacgctctg atgcggatag agcagatgtt tgaacaaccg ctgtacattc atttgtatcg
     6541 gcacccctgt ggaatgattc ggtctttcgt aaacgcacac ctagatcaaa tatttttccg
     6601 tcacgaccat tgtcttgagg cttccgcatt aggtgaactt atttggaacc ggagccatca
     6661 aaatatacgc aagacgcttc ataatattcc gagcactcgg aagattttgg ttaattttga
     6721 ggctttgact cgacaaacca ggcatgagct tgagcgggtt tgtgagtttc ttgatctacc
     6781 ctttgatcag agaatgctcg acctttacag cgattcctcg ggccgcatga ccgatggagt
     6841 aaggcaagaa tcacgcatga tcggtgatgt acgtttccat cagcataaga agatagaaga
     6901 agatgtcggc agcgcttggg aagaccagat gcgtttcgag gagttgtcag aagatactca
     6961 gcatgtttgg tctaatctga ggtcttcgga aggggagaag cttccagatt ctaatgagga
     7021 tcttggcgga tgctcccaaa ctagctggca tccgtcgtta tctcaagagc gaatatggtt
     7081 tctcgatcag ctagacgact cttcgcgggc ctatacgatt cctggcgcga tgatgctcga
     7141 tggggctctg aatgaaacag cattcaacaa tgctgtactc agacttacag agcggcatgt
     7201 tgttctaaat agtaggttca tgaaagttga gggagaggtg cgtgtcgatg tgagtcaaag
     7261 ccatcagggt gttacctggg gtgatgtttc taaagtagaa cgcacagacc gggaggaggc
     7321 gatctcagcg tttgtgtcag agaacgcaaa gcatcaattc gacctcagcc aaggtgggtt
     7381 gtttagggtt gaaatagtca gagttgatga acgtagattt ttgttgttag taaacctcca
     7441 ccacatcgtt tgtgatggat ggtccttaga tattctgttt tcagagttga gcgctcttta
     7501 caatgccgaa gtcgacgggt gtcgggatgg actgagcccg ttatccgtgt cttttggaga
     7561 ttacgctaac tggcaaagag agcaggcgac caataacagg gttaaaaagc agcttaccta
     7621 ttggcgcgag cagttatcgg gccttccccc agcgctagaa ctgccaacag acttcctaag
     7681 aaaatcagtc cagactttta acggcgaccg ggtgcaagtt tctcttgata cagaggtttc
     7741 aaacaatatc cgcaagtact gcaatgatcg aggttgtacg gtgtttatgt atttgcttgc
     7801 taactttgcc ctgttacttg gcaggatcac tggatcggaa gacatcccga tagggacacc
     7861 cacatcggcc cgaccaagaa aggaatttga aggtttagtt ggattttttg cgaatacgct
     7921 ggttcttcga ttgcggcttg ggcaggttgg ttttgatgag gttctcgctg caacacgcca
     7981 gacctgcctc gacgcattgt ctaaccagga catctccttt gagcaattgg tttctgcagt
     8041 ccagccagat cgcaatctca gtgtttctcc gattttccaa gtgatgtttt ctttgcaacg
     8101 caagtcatca actacattga gattctcaac aataaaagcg acccctatcg aaacctctat
     8161 tgattcaacg aaatatgatc ttagcctcct tcttgaagac cacgactcta cgataaaggg
     8221 ctgcttcgag tttaatcggg atctttttgc taaccaacgg atagagtttc ttagcgatca
     8281 gtttgtcaac ttggtcaaaa gaaatctttg ccacgaatcc acgattagca cgtcggtgaa
     8341 ttattacggg gctgctgaga atgccttcct agcgcgattt ggacaaggca aagtgactac
     8401 gatgcctgtt ccgcagcttg tagggcaatg gatagatatt ggaataaaac ggagtcctgg
     8461 ggatgcggtc gcggttcgat tccaggggca gagcctaact tatacagagc tcgggctcga
     8521 agttgaaact gcagccttgt gtctgaggaa tcttggtatc ggtgctggag atcgtgtcgg
     8581 cgtatgttac cgaagagatc tgcacctagt tccctggttg cttggtattt tgaatattgg
     8641 ggcatgttac gttccgcttg atcccgcgct gccagatgag cggttggatt ttatcttggt
     8701 cgattcggac ctttccaagg tactatgcag tgaagaatat gcagggcgaa gctgtttcaa
     8761 ggagataaca actttccatc gcgaactgag cggagcccag gacaaggcat caagaagcgt
     8821 tgctacggat gtatcagagc aaagtgcggc ctatatttgc tacacctcgg gctctactgg
     8881 gataccaaag ggagtgccgg ttagccatcg atcagttgtt aatcttctca ctgcaatgca
     8941 gaagctgctg cgcttgacgc ccagtgataa atgggttgcg attacgacac tctcgtttga
     9001 catccatgtg ccagaattac tgttgccttt gggcgttggt gggcaggtct gcctcgcgag
     9061 tgaatcggaa gcccgtgacc cgaggcaatt gataaatctc ctcgcgaccc ataaggctac
     9121 agtgctccag gcaacgccct ccacttggca cagtattgag gtcgcaggtt gggagggaga
     9181 accaggactt agggcattat ccggcgggga ggccttgtcc cgggacctcg caacaagtct
     9241 cctgcccaaa gtggactccc tctggaatat gtatggtcca accgagacga ccgtctggtc
     9301 aagtgcgcaa caggtgacaa aagaagaact tttgatacga aattcggtcg cgattggtcg
     9361 ccccctttta aataccacat tctatgtcgt cgacaagacc cggcgggcgc taccagtcgg
     9421 tgcttggggg gagttggcga taggtggaga gggagtctgc gatgggtatc ttaaccgccc
     9481 ggatctcgcc gtaggccgtt ttgtgactct gcctgatttt gatagtcaat cgcgtgctta
     9541 tctaacgggg gaccgcgtgc ggctgaccga gtcaggtatc tttgaagtct ccggccgttt
     9601 tgacaaccag atcaaagttc gtggtgtgcg ggtcgagccc gaggagatag aggccgtatt
     9661 ggaaaaacac ccggaagttc ttcgggctgt tgtcgtgctg aaagaactaa cccaaaacga
     9721 gaaaatcttg attggcgtga tagcagtgga accgcctcat cgaaaaagtg taactcaaga
     9781 ggtccttcga tttgctgaga aaattctgcc ggccacaatg gttcctggtc ggttggtatg
     9841 cctagaggaa ctcccaataa cgcctaacgg caaagtagat cgtggacgta tcctgccgat
     9901 cctcgatcag gatgaggcgg atcttatcga cgatccttcg atagagacga acatcgcaac
     9961 tgtgggaaga gatgttattg agttaaaact cgtaagccta tggcgcaaat accttggtgt
    10021 tccgaatatc cgtgtggatg acaatttttt cagtgttggg gggcattctc ttctcgcggt
    10081 gcgactcatt gcggctgttg aaaaagaatt taagcaacag ttacctcttg cggcactgtt
    10141 tgaaatgccg acagtcagac ttatggcgga gaaattgcgg gccgatggtg gtatgagtga
    10201 attgtggtcc agaccaattg agctacgcac gggatcggaa cacctaacat tgtttttggt
    10261 gcccggtgcg ggtggcaatg tgctttactt tcaggaattg gcgaaaaatt gcccggtagg
    10321 agttcgggta gttgcgctgc aacctcccgg gctagatggt gtacaccccc cagttggtac
    10381 tatagaaggc ctagccgatc tatttctcga ccagatccaa gaacaactcc atgaagagat
    10441 ggataaagtg gtcgtgatag gccattcctt tggcggcttg gttgcctacg agatggcgtg
    10501 tcgtgcacac actaaatcta tggtgatcga ttctctattc attatagata cagcagcccc
    10561 gaatttagcc gaatctactg gtcgggattg gtctcacgag gagtggattt gccatttaag
    10621 tcaaattgcg ggctacatgt ttgatgtgga tgtagaagta tttcaacagg aggttgcagg
    10681 gcttaatgac atttcgcaga tagaagtgtt ccatcataag ttggttgatg caggggtaat
    10741 cgctgttggg gtgagcgcac aatttgtatc aggccttgtc aacgtttacc gatcgaatct
    10801 atgcgccgaa ccacctcagg gccttttgcc gaatgaggat atggctccaa caatcattag
    10861 gtcactacaa gagcaacccg gtcatttgag tgacgagacc agccgacgaa atagattgca
    10921 cggtgatctt ggttgggagg aatatctagg ctatcctgta aaggtaatag atgcacccgg
    10981 tgatcacttg actatgctgc aggacagtaa tgccggagta ttagctaaga taatttgtgg
    11041 taaagtattc taaatttaaa atttcttata ggactaaaat gatgcgaaac tacgcgctct
    11101 cccttctttt cacgttgctc ggattattct cggcagtagt tcaggccgct caggtcgccg
    11161 ataagaattt tcatcctcaa gttgcaactc ctgcattttc gaaagggagt gggcctgtcg
    11221 ttgcggtcga tgccgctcat gcgaatttcc atacgtgcga gggtcgctac attgcatttt
    11281 gtgagttact gggcaatgac ggttatcgca tcaaaacaaa caacgactca ttttcaatgg
    11341 aaaacctgaa tactatcgat ttactggtta ttgccaatgc attaaacaag aagaatatcg
    11401 atcctaaaca gaattgggcc acgcccattc tcccggcatt taccgaaaag gagacacaga
    11461 atctagtaaa atgggttaag tcggggggcg cactgcttgt tattgctgat cacatgccct
    11521 ttcccggtgc ggtaagtgat cttggcctca agtttggggt taactggggt aacagttacg
    11581 cttttgcggc cgacacgcag attgtcgagg cagctaagaa gaataccctg tcagtgatta
    11641 agggtccgga tgccaacatg atgaccttcg atttgaaagg tcttaactca accggggtgc
    11701 aggcataccc ccatccaatt tttcatggcc gtaacccaac agagaacgtc ccatttatca
    11761 ccacgttcac cggctcggca tttacacttc ttccgggttc tcaagtgaac cccctaatgg
    11821 gtcttggcga gggcacgttg cttatgtttc cgcttaaatc tcaagagcag tcgctgatga
    11881 cgccacgagg tcccggggcc ggcacactcc aaggaggcgt gttggaattt ggtaaaggcc
    11941 gggtagcgat aatgggggag gcgtccatgt tctcagccca gatcgcagac tacatctccc
    12001 caggcttcaa aatgggcatg aataatactg agcacgcacc tcacaatgtc cagttcgcgt
    12061 taaacctgac ccactggcta acgaagataa ataattgatt gatacatttg ttaaggagct
    12121 taagacatag tggaaaaaga gccgagtgta aatgagagcg aaaacaagtc ggttgtcgaa
    12181 cgtattcagc gcctcgagaa gactaccaag ataatgcttg gcttggctgt gggagctgta
    12241 gctatcagtg tagtgggtgc tgcgttgtta ccgctgaagc tcaaggtggc actgccgaaa
    12301 ttggggataa aggttctctc ttaggctcac atcgttgtgt gcaggttgtt tggccgcggg
    12361 cccgtcaagg taaatgatga ttaactgcct gggctagtgg cctagcctgg cgagtgagga
    12421 cggccagcgc cttgtaatga agtaaagcgg gagagggttt ttcgccttta gtgtattgca
    12481 gaactactga aagctgattt ttcctggcgg aaaaaacaag tgtcatccgc agcgttcgaa
    12541 tatttaaaaa tattctgtct ttggcgcgac tgcccccgcg gaagttgaag ttaatctgac
    12601 attccacttc accagaccga ctgcctacag tggagtcgat tttagcgtcg agttcaattg
    12661 ggaccaaaga agtaaacgca gcttttacag atgttggttc gaccgctatc ttttgaagac
    12721 gtataaattt cggcagatca ggcgtgaaag ccttaataaa cttgtcagga cagctgaaaa
    12781 gggttacgac atctgagctt tttggctgct ttgatagttg ataggttttt tgcgctattt
    12841 ttatcaaatt tcggtcacac ccttataaca tcaggcggct gttgctgtga acgtagcgtc
    12901 tagtttggca aagccttgca actggaaaac aaatttagat gaaactgtat tgctacatat
    12961 tactgtaact cggcccaccg ccgccctcgg gagttaccca ggtgatgttc tggctgggat
    13021 ccttgatatc gcaggtcttg cagtggatac agttctgggc gtttatctgg aagcgctggt
    13081 ctaggccttc gttgacgatt tcgtagaccc ccgccgggca gtagcgttgg gccggctcgg
    13141 cccaacgagg cagattaact ttaagcggaa gatcggcatc ggcaagatgc aggtgcaccg
    13201 gttgatcttc ttcgtggttg gtattggtca ggaaaactga cgagtttttg tcaaaggtca
    13261 gcactccgtc aggcttgggg tagtcgatcg gtgtggcgtt atcgacctct ttgagagcgt
    13321 tgtgatcgac agtgttgtct tttagcgtga aaggtaattt gccacgcagc cagttctgat
    13381 cgacgtaatt gaatgctccg
//
