LOCUS       c00278_3300023..        4106 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300023169.a:Ga0247762_1003618.
ACCESSION   c00278_3300023..
VERSION     c00278_3300023..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 07:50:18
            Original ID  :: 3300023169.a:Ga0247762_1003618
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4106
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4106
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:4100](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(3..4100)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..4106
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..4106
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             complement(3..4100)
                     /NRPS_PKS="Domain: AMP-binding (289-691). E-value:
                     1.4e-101. Score: 331.8. Matches aSDomain:
                     nrpspksdomains_ctg278_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (797-865). E-value: 4.1e-21. Score:
                     66.7. Matches aSDomain: nrpspksdomains_ctg278_1_PCP.1"
                     /NRPS_PKS="Domain: Condensation_DCL (904-1198). E-value:
                     3e-50. Score: 162.7. Matches aSDomain:
                     nrpspksdomains_ctg278_1_Condensation_DCL.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     319.8; E-value: 4.3e-97)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg278_1"
                     /sec_met_domain="Condensation (E-value: 1.9e-45, bitscore:
                     141.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 5e-113, bitscore:
                     363.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 5.6e-15, bitscore:
                     41.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRGLHDEVAAPLQYSQFAQWQNENTEAVPEEALQLFSALTASKPE
                     VLLPFQNGHNTLEISDYRRHTFDIPADLLNQVELFCDKNNCPVEDFLFAAWALLLYRLS
                     GGTAIEAGIADHRREHDVLNDCLGLVSKVLPVQLHIQADGVFTSLLKTAGQNIRGISDW
                     KDYFILDTSSSPAYGFDFSDVSLRPSGSMARYYGHSQDTRTFKLNLNIIRSGRDTAANL
                     EYDAGTFTEKNIETICESFVVLIAGIINDPGCAVDSLPLLSEATQSYILNDLNPAHQPI
                     PAVTIVDLLEQQVQANPDRIAVVYNNECLTYSQLNARANQVAHTLRNQYQVSANEMVAI
                     LLPRSQKMIISILGILKAGAAYLPVSTDQPAQRITDILRESGARVLLTDNTIDTANFNL
                     TTLNIDDTKIDDQPSHNPVRINRPEDLAYVIFTSGSTGTPKGVAIEQASLVNLYKGLKQ
                     AVYGEPVAIMNVALLASYAFDASVPQIFCTLFDGHTLHVIDSDTRNDANKLFEYVRDHA
                     IHSLDCTPSLLSVFLDAGKSRFNELVLRHILVGGESLTPDVVNKLFADTSYTGGIRISN
                     VYGPTEGTVECTCYNVPDAGEIESVSIGKPMLNRRLYILNKAMQPVPVGVTGEIYIGGA
                     GLFREYINAKTLTEERLVNNPFVAGEQLYRSGDLGRWLESGEIMYSGRGDEQVKIRGYR
                     VELGEIQSAILRHEDVKEALVVVRGEEDKQIVAYYVSTTSLMPGELNGFVKDQLPAYMV
                     PAHFMALEKFPVNNNGKIDRNALPDPASISTGAQTQFASPRTDFEKRVADIFAAGLGLK
                     EIGIHDDFFALGGDSLKAIRIISRLNKELDTTLKIGDIFVNETIEKLVGSMKRSNESPG
                     LQNELAAGYQKIEKVKTQLLASHPQWMQQIENIEDIYPLTPTESGMIYSSLLNVEEPVY
                     YDLFTYQVGIKDFAHFEQALQHMIQRHAIFRTRYYMSRFDDSVKITFKKIELPFSLEDL
                     SALNPSEQQNTIRIYQERDLAIRLSFDGDLLWRFKAFCLGDDKYYIAWSVHHAMLDGWS
                     LAIFTTELSKLLSGEALTPLKNTYKDHCALVLGQQVSPGVERFWKTLLENYSRNKLPFN
                     PSGKRRTGKTGTATLRKTIDLKVLKDLEAIVAKEGVSLKAISLAAYVYMMSVLSSETDV
                     VTGVVSHDRPAIEDGDKILGCFLNTLPVRINLADLSSNLSLIRKVNQYLVDAKPNELHL
                     TEIANMIGEKASAGNPIFDCILNYTDFHVLNEWAESENLDSDAEVMEDASALVMSGITN
                     TLFDLEIDKSHGGFLAQIKYAQAYFEAAEISSALDLYVRILEHFADNIQGSLSDIDLLS
                     QAERRFLLQELNNTVVPYSNDKC"
     aSDomain        complement(507..1388)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg278_1_Condensation_DCL.1"
                     /domain_subtype="Condensation_DCL"
                     /evalue="3.00E-50"
                     /label="ctg278_1_Condensation_DCL.1"
                     /locus_tag="ctg278_1"
                     /protein_end="1198"
                     /protein_start="904"
                     /score="162.7"
                     /tool="antismash"
                     /translation="EDIYPLTPTESGMIYSSLLNVEEPVYYDLFTYQVGIKDFAHFEQA
                     LQHMIQRHAIFRTRYYMSRFDDSVKITFKKIELPFSLEDLSALNPSEQQNTIRIYQERD
                     LAIRLSFDGDLLWRFKAFCLGDDKYYIAWSVHHAMLDGWSLAIFTTELSKLLSGEALTP
                     LKNTYKDHCALVLGQQVSPGVERFWKTLLENYSRNKLPFNPSGKRRTGKTGTATLRKTI
                     DLKVLKDLEAIVAKEGVSLKAISLAAYVYMMSVLSSETDVVTGVVSHDRPAIEDGDKIL
                     GCFLNTLPVRINLA"
     aSModule        507..1388
                     /domains="nrpspksdomains_ctg278_1_Condensation_DCL.1"
                     /incomplete
                     /locus_tags="ctg278_1"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(516..608)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg278_1_0008"
                     /evalue="1.30E-07"
                     /label="C5_DCL_263-294"
                     /locus_tag="ctg278_1"
                     /protein_end="1195"
                     /protein_start="1164"
                     /score="24.1"
                     /tool="antismash"
                     /translation="DVVTGVVSHDRPAIEDGDKILGCFLNTLPVRI"
     CDS_motif       complement(927..986)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg278_1_0007"
                     /evalue="9.20E-08"
                     /label="C3_DCL_135-156"
                     /locus_tag="ctg278_1"
                     /protein_end="1058"
                     /protein_start="1038"
                     /score="24.6"
                     /tool="antismash"
                     /translation="VHHAMLDGWSLAIFTTELSKL"
     CDS_motif       complement(1161..1208)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg278_1_0006"
                     /evalue="7.10E-01"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg278_1"
                     /protein_end="980"
                     /protein_start="964"
                     /score="3.1"
                     /tool="antismash"
                     /translation="YMSRFDDSVKITFKKIE"
     CDS_motif       complement(1209..1277)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg278_1_0005"
                     /evalue="2.20E-08"
                     /label="C2_DCL_024-062"
                     /locus_tag="ctg278_1"
                     /protein_end="964"
                     /protein_start="941"
                     /score="26.4"
                     /tool="antismash"
                     /translation="DFAHFEQALQHMIQRHAIFRTRYY"
     aSDomain        complement(1506..1709)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg278_1_PCP.1"
                     /evalue="4.10E-21"
                     /label="ctg278_1_PCP.1"
                     /locus_tag="ctg278_1"
                     /protein_end="865"
                     /protein_start="797"
                     /score="66.7"
                     /tool="antismash"
                     /translation="EKRVADIFAAGLGLKEIGIHDDFFALGGDSLKAIRIISRLNKELD
                     TTLKIGDIFVNETIEKLVGSMKRS"
     aSModule        1506..3233
                     /complete
                     /domains="nrpspksdomains_ctg278_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg278_1_PCP.1"
                     /locus_tags="ctg278_1"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(1998..2063)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg278_1_0004"
                     /evalue="3.20E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg278_1"
                     /protein_end="701"
                     /protein_start="679"
                     /score="32.1"
                     /tool="antismash"
                     /translation="YSGRGDEQVKIRGYRVELGEIQS"
     aSDomain        complement(2028..3233)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg278_1_AMP-binding.1"
                     /evalue="1.40E-101"
                     /label="ctg278_1_AMP-binding.1"
                     /locus_tag="ctg278_1"
                     /protein_end="691"
                     /protein_start="289"
                     /score="331.8"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="LEQQVQANPDRIAVVYNNECLTYSQLNARANQVAHTLRNQYQVSA
                     NEMVAILLPRSQKMIISILGILKAGAAYLPVSTDQPAQRITDILRESGARVLLTDNTID
                     TANFNLTTLNIDDTKIDDQPSHNPVRINRPEDLAYVIFTSGSTGTPKGVAIEQASLVNL
                     YKGLKQAVYGEPVAIMNVALLASYAFDASVPQIFCTLFDGHTLHVIDSDTRNDANKLFE
                     YVRDHAIHSLDCTPSLLSVFLDAGKSRFNELVLRHILVGGESLTPDVVNKLFADTSYTG
                     GIRISNVYGPTEGTVECTCYNVPDAGEIESVSIGKPMLNRRLYILNKAMQPVPVGVTGE
                     IYIGGAGLFREYINAKTLTEERLVNNPFVAGEQLYRSGDLGRWLESGEIMYSGRGDEQV
                     KIRG"
     CDS_motif       complement(2148..2234)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg278_1_0003"
                     /evalue="8.70E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg278_1"
                     /protein_end="651"
                     /protein_start="622"
                     /score="34.1"
                     /tool="antismash"
                     /translation="PVGVTGEIYIGGAGLFREYINAKTLTEERL"
     CDS_motif       complement(2766..2822)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg278_1_0002"
                     /evalue="7.00E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg278_1"
                     /protein_end="445"
                     /protein_start="426"
                     /score="30.8"
                     /tool="antismash"
                     /translation="AYVIFTSGSTGTPKGVAIEQ"
     CDS_motif       complement(3006..3044)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg278_1_0001"
                     /evalue="1.20E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg278_1"
                     /protein_end="365"
                     /protein_start="352"
                     /score="15.3"
                     /tool="antismash"
                     /translation="LGILKAGAAYLPVS"
ORIGIN
        1 aggcacttgt cgtttgaata gggtactacg gtattattga gctcctggag caggaagcgg
       61 cgttcggcct ggctcagcag gtcgatatcg ctgagggagc cctggatgtt gtcagcgaag
      121 tgctcgagta tacgaacgta taagtccagt gctgacgaga tctcggcagc ttcgaaatag
      181 gcctgcgcat attttatctg tgccagaaaa ccaccgtgtg acttatctat ctccaggtcg
      241 aaaagcgtgt tggtgatgcc cgacataaca agcgcggagg catcttccat cacttcggca
      301 tcggagtcga ggttttcgct ttccgcccat tcgttcagaa catgaaaatc tgtatagttt
      361 aaaatacaat cgaatatagg attgccggca gaagcttttt caccaatcat attggcaatc
      421 tctgtcaggt gaagctcgtt cggttttgcg tctaccaggt attgattcac tttacggatc
      481 aacgacaggt tgctgctcag atcggccagg ttgatacgaa ccggcaatgt gttcaggaaa
      541 cagcccagta tcttgtcgcc gtcttctata gccggacggt catgtgaaac gacgccggtc
      601 actacatcgg tttccgagct gagtactgac atcatataga cgtacgcggc aagagagatt
      661 gcctttaatg aaacgccctc tttggccact attgcctcga gatcttttaa aactttgagg
      721 tcaatagttt tgcgtagtgt ggctgtgccg gttttgccgg tgcggcgctt acccgaaggg
      781 ttgaagggaa gcttgttacg gctatagttt tccagcaagg tcttccagaa gcgttccact
      841 ccgggcgaaa cctgctggcc aagcacaaga gcgcagtgat ctttgtaagt attcttcagc
      901 ggtgtcagtg cctcgcccga caatagcttc gataattccg ttgtaaatat cgcaaggctc
      961 cagccgtcga gcatggcatg gtgcacactc caggcaatat agtatttatc gtcgcccaga
     1021 cagaacgcct tgaagcgcca gagcagatcg ccgtcaaacg ataaccggat ggcaaggtct
     1081 ctttcctggt aaattcgtat ggtattctgc tgttcggaag ggttcagggc cgacaggtct
     1141 tccaacgaga acggtaattc gatcttcttg aacgtgatct ttacagaatc gtcgaaacgc
     1201 gacatatagt atcgcgtacg gaatatggcg tggcgttgga tcatgtgctg caacgcctgt
     1261 tcaaaatgag caaaatcttt tataccgacc tggtaagtaa acaggtcgta gtacaccggc
     1321 tcttctacat tgagcagcga cgagtagatc ataccactct ccgtgggtgt aagcggataa
     1381 atgtcttcta tattttcgat ctgctgcatc cattgcgggt ggctggccag cagttgcgtt
     1441 tttaccttct ctattttctg atagccggcg gctaactcgt tttgtaaccc cggactctcg
     1501 ttgctccgtt tcatcgagcc tacgagcttt tcgatagttt cattaacaaa aatgtcgcct
     1561 atcttcagtg ttgtgtcaag ctctttgttt aacctggata tgatccggat agctttcagg
     1621 gagtcgccgc ccaatgcaaa gaaatcatcg tgtataccta tttctttcag ccccagcccc
     1681 gcggcaaaaa tatcggccac gcgtttttca aaatcggtac gcggtgatgc aaattgtgtc
     1741 tgcgcgccgg tgcttatact tgcgggatcg ggtaatgcat tccgatcgat ctttccattg
     1801 ttattgacag ggaatttttc cagcgccatg aaatgtgccg gcaccatata agcgggaagc
     1861 tgatctttaa cgaatccgtt cagctcaccg ggcattagcg aggtagtgct cacataatag
     1921 gctacaattt gtttgtcttc ttcaccacgt actactacca gcgcctcctt cacatcttcg
     1981 tggcgtagta tagccgattg gatttcgccc agctctacgc ggtagccgcg gatctttacc
     2041 tgctcgtcgc ctcttccgga atacatgatc tctccgcttt cgagccaccg tcccaggtcg
     2101 ccgctacgat agagctgttc tccggccacg aacgggttat tcaccagcct ttcttcggtt
     2161 agtgttttgg cgttaatgta ttcgcggaac aggcccgctc ccccgatata gatttcgccg
     2221 gttacgccta ccggtacagg ctgcatggcc ttattcagaa tatacagtcg ccggtttagc
     2281 atcggcttac cgatcgatac cgattcaatt tcgcctgcat cgggtacgtt atagcacgtg
     2341 cattccacgg ttccttcggt tggtccatat acgttggaga tcctgatacc acccgtgtag
     2401 gatgtgtcgg cgaagagttt gtttaccaca tcgggtgtta gcgattcgcc gccaacaagg
     2461 atatgacgca acaccagctc gttaaaccgg ctcttgccgg cgtccagaaa tactgatagc
     2521 agcgacggcg tacaatcgag cgaatgaata gcgtgatccc gcacgtactc gaagagcttg
     2581 tttgcatcgt tccgggtatc tgaatcgata acgtgcagcg tatggccatc gaagagagtg
     2641 cagaatatct gaggtacgga tgcatcgaac gcatagcttg ccagcagcgc tacattcata
     2701 atggccactg gctcgccgta aactgcctgt ttgagtcctt tataaagatt taccagcgat
     2761 gcctgttcga ttgccacgcc tttgggagtt cccgtagagc ccgaggtgaa gattacgtat
     2821 gcgagatcct caggccggtt tatcctgaca ggattgtgag aaggttggtc gtcgatcttt
     2881 gtatcgtcta tattgagcgt cgtcaggttg aagtttgcag tgtcgatggt attatctgtc
     2941 agcaataccc gggcgccact ctcgcgaagt atgtcggtga tgcgctgcgc gggttggtct
     3001 gtactgactg gcaggtaggc ggccccggct ttgaggatgc cgagaatgct gatgatcatt
     3061 ttttgagaac gaggcagcag gatggcgacc atctcgttag cgctcacctg gtattggttt
     3121 cgcagggtat gagccacctg gttggcccgg gcgttcagct gactgtaggt aaggcattcg
     3181 ttattataca ctacagcaat gcggtcggga tttgcctgca cctgctgctc gagcagatcg
     3241 acaattgtta cagccggaat gggttggtgc gctggattca gatcgttgag aatataactt
     3301 tgtgtagctt cgctcagtaa aggcaatgag tcaacggcac aacccggatc attgatgata
     3361 cccgcgatca gaaccacgaa gctttcgcaa atggtctcga tattcttttc ggtaaaggtt
     3421 cccgcatcgt attccaggtt ggccgcggtg tcccttcctg atcgtataat attcaggttt
     3481 aatttaaaag tcctggtatc ctggctgtgc ccgtagtaac gggccatgct gcccgaaggc
     3541 ctgagcgaaa cgtctgagaa gtcgaatcca taggcaggcg atgatgatgt gtcgagtata
     3601 aaatagtctt tccagtctga aataccgcgg atgttctgcc cggcagtttt cagtaacgag
     3661 gtgaacacgc catctgcctg tatgtgtaac tgcaccggga gcaccttcga caccaggccg
     3721 aggcagtcgt tcagtacatc gtgctcgcgt cggtgatcag cgatccctgc ctctatagcg
     3781 gtgccacccg atagccggta caacagcagt gcccaggcag cgaaaagaaa atcctctacc
     3841 gggcagttgt ttttatcgca gaataactca acctggttca acaggtcagc cggtatgtcg
     3901 aacgtgtggc gccggtagtc tgatatttcc aacgtgttat gtccgttctg gaagggcagc
     3961 aggacctccg gtttggaagc tgtaagggcg ctgaaaagct gaagggcttc ctctggcaca
     4021 gcttcggtat tttcgttttg ccattgcgca aattgagaat actgcagggg ggcggcgact
     4081 tcgtcatgta gcccacgcac ctattg
//
