3300023201_7 - 14 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

c00008_3300023.. (original name was: 3300023201.a:Ga0256614_1016603)

Region	Type	From	To	Most similar known cluster		Similarity
Region 8.1	NRPS-like	55,069	77,347

c00009_3300023.. (original name was: 3300023201.a:Ga0256614_1003103)

Region	Type	From	To	Most similar known cluster		Similarity
Region 9.1	bacteriocin	475	11,356

c00010_3300023.. (original name was: 3300023201.a:Ga0256614_1088372)

Region	Type	From	To	Most similar known cluster		Similarity
Region 10.1	bacteriocin	45,540	55,761

c00016_3300023.. (original name was: 3300023201.a:Ga0256614_1041240)

Region	Type	From	To	Most similar known cluster		Similarity
Region 16.1	terpene	1	11,304

c00021_3300023.. (original name was: 3300023201.a:Ga0256614_1532417)

Region	Type	From	To	Most similar known cluster		Similarity
Region 21.1	NRPS,T1PKS	1	80,486

c00047_3300023.. (original name was: 3300023201.a:Ga0256614_1158328)

Region	Type	From	To	Most similar known cluster		Similarity
Region 47.1	terpene	72,885	94,858

c00049_3300023.. (original name was: 3300023201.a:Ga0256614_1464239)

Region	Type	From	To	Most similar known cluster		Similarity
Region 49.1	hserlactone	56,922	77,659
Region 49.2	T1PKS,NRPS	91,264	129,090

c00050_3300023.. (original name was: 3300023201.a:Ga0256614_1172828)

Region	Type	From	To	Most similar known cluster		Similarity
Region 50.1	NRPS	74,026	128,768

c00052_3300023.. (original name was: 3300023201.a:Ga0256614_1493712)

Region	Type	From	To	Most similar known cluster		Similarity
Region 52.1	NRPS	1	3,207

c00074_3300023.. (original name was: 3300023201.a:Ga0256614_1036555)

Region	Type	From	To	Most similar known cluster		Similarity
Region 74.1	hserlactone	1	20,749

c00078_3300023.. (original name was: 3300023201.a:Ga0256614_1389656)

Region	Type	From	To	Most similar known cluster		Similarity
Region 78.1	arylpolyene	1	39,790

c00084_3300023.. (original name was: 3300023201.a:Ga0256614_1083341)

Region	Type	From	To	Most similar known cluster		Similarity
Region 84.1	bacteriocin	40,520	51,371

c00095_3300023.. (original name was: 3300023201.a:Ga0256614_1493542)

Region	Type	From	To	Most similar known cluster		Similarity
Region 95.1	NRPS	1	19,486

Region	Type	From	To	Similarity
Region 8.1	NRPS-like	55,069	77,347
Region 9.1	bacteriocin	475	11,356
Region 10.1	bacteriocin	45,540	55,761
Region 16.1	terpene	1	11,304
Region 21.1	NRPS,T1PKS	1	80,486
Region 47.1	terpene	72,885	94,858
Region 49.1	hserlactone	56,922	77,659
Region 49.2	T1PKS,NRPS	91,264	129,090
Region 50.1	NRPS	74,026	128,768
Region 52.1	NRPS	1	3,207
Region 74.1	hserlactone	1	20,749
Region 78.1	arylpolyene	1	39,790
Region 84.1	bacteriocin	40,520	51,371
Region 95.1	NRPS	1	19,486

No secondary metabolite regions were found in these records:: c00001_3300023.. (original name was: 3300023201.a:Ga0256614_1481621); c00002_3300023.. (original name was: 3300023201.a:Ga0256614_1296307); c00003_3300023.. (original name was: 3300023201.a:Ga0256614_1275044); c00004_3300023.. (original name was: 3300023201.a:Ga0256614_1268397); c00005_3300023.. (original name was: 3300023201.a:Ga0256614_1033563); c00006_3300023.. (original name was: 3300023201.a:Ga0256614_1237963); c00007_3300023.. (original name was: 3300023201.a:Ga0256614_1295540); c00011_3300023.. (original name was: 3300023201.a:Ga0256614_1544881); c00012_3300023.. (original name was: 3300023201.a:Ga0256614_1530962); c00013_3300023.. (original name was: 3300023201.a:Ga0256614_1000790); c00014_3300023.. (original name was: 3300023201.a:Ga0256614_1004616); c00015_3300023.. (original name was: 3300023201.a:Ga0256614_1472102); c00017_3300023.. (original name was: 3300023201.a:Ga0256614_1136838); c00018_3300023.. (original name was: 3300023201.a:Ga0256614_1221075); c00019_3300023.. (original name was: 3300023201.a:Ga0256614_1384558); c00020_3300023.. (original name was: 3300023201.a:Ga0256614_1222902); c00022_3300023.. (original name was: 3300023201.a:Ga0256614_1351847); c00023_3300023.. (original name was: 3300023201.a:Ga0256614_1260782); c00024_3300023.. (original name was: 3300023201.a:Ga0256614_1434469); c00025_3300023.. (original name was: 3300023201.a:Ga0256614_1082096); c00026_3300023.. (original name was: 3300023201.a:Ga0256614_1297383); c00027_3300023.. (original name was: 3300023201.a:Ga0256614_1205145); c00028_3300023.. (original name was: 3300023201.a:Ga0256614_1419418); c00029_3300023.. (original name was: 3300023201.a:Ga0256614_1110284); c00030_3300023.. (original name was: 3300023201.a:Ga0256614_1030072); c00031_3300023.. (original name was: 3300023201.a:Ga0256614_1068459); c00032_3300023.. (original name was: 3300023201.a:Ga0256614_1410678); c00033_3300023.. (original name was: 3300023201.a:Ga0256614_1043568); c00034_3300023.. (original name was: 3300023201.a:Ga0256614_1147676); c00035_3300023.. (original name was: 3300023201.a:Ga0256614_1493160); c00036_3300023.. (original name was: 3300023201.a:Ga0256614_1104038); c00037_3300023.. (original name was: 3300023201.a:Ga0256614_1479790); c00038_3300023.. (original name was: 3300023201.a:Ga0256614_1054564); c00039_3300023.. (original name was: 3300023201.a:Ga0256614_1251651); c00040_3300023.. (original name was: 3300023201.a:Ga0256614_1453005); c00041_3300023.. (original name was: 3300023201.a:Ga0256614_1106947); c00042_3300023.. (original name was: 3300023201.a:Ga0256614_1268890); c00043_3300023.. (original name was: 3300023201.a:Ga0256614_1101379); c00044_3300023.. (original name was: 3300023201.a:Ga0256614_1433369); c00045_3300023.. (original name was: 3300023201.a:Ga0256614_1311998); c00046_3300023.. (original name was: 3300023201.a:Ga0256614_1230098); c00048_3300023.. (original name was: 3300023201.a:Ga0256614_1042568); c00051_3300023.. (original name was: 3300023201.a:Ga0256614_1286740); c00053_3300023.. (original name was: 3300023201.a:Ga0256614_1257975); c00054_3300023.. (original name was: 3300023201.a:Ga0256614_1095260); c00055_3300023.. (original name was: 3300023201.a:Ga0256614_1265052); c00056_3300023.. (original name was: 3300023201.a:Ga0256614_1505768); c00057_3300023.. (original name was: 3300023201.a:Ga0256614_1052782); c00058_3300023.. (original name was: 3300023201.a:Ga0256614_1125038); c00059_3300023.. (original name was: 3300023201.a:Ga0256614_1012866); c00060_3300023.. (original name was: 3300023201.a:Ga0256614_1270328); c00061_3300023.. (original name was: 3300023201.a:Ga0256614_1364848); c00062_3300023.. (original name was: 3300023201.a:Ga0256614_1414466); c00063_3300023.. (original name was: 3300023201.a:Ga0256614_1241092); c00064_3300023.. (original name was: 3300023201.a:Ga0256614_1509387); c00065_3300023.. (original name was: 3300023201.a:Ga0256614_1059635); c00066_3300023.. (original name was: 3300023201.a:Ga0256614_1513438); c00067_3300023.. (original name was: 3300023201.a:Ga0256614_1087839); c00068_3300023.. (original name was: 3300023201.a:Ga0256614_1043575); c00069_3300023.. (original name was: 3300023201.a:Ga0256614_1156686); c00070_3300023.. (original name was: 3300023201.a:Ga0256614_1242404); c00071_3300023.. (original name was: 3300023201.a:Ga0256614_1287881); c00072_3300023.. (original name was: 3300023201.a:Ga0256614_1126864); c00073_3300023.. (original name was: 3300023201.a:Ga0256614_1164086); c00075_3300023.. (original name was: 3300023201.a:Ga0256614_1188049); c00076_3300023.. (original name was: 3300023201.a:Ga0256614_1059273); c00077_3300023.. (original name was: 3300023201.a:Ga0256614_1263881); c00079_3300023.. (original name was: 3300023201.a:Ga0256614_1426819); c00080_3300023.. (original name was: 3300023201.a:Ga0256614_1433556); c00081_3300023.. (original name was: 3300023201.a:Ga0256614_1064475); c00082_3300023.. (original name was: 3300023201.a:Ga0256614_1201588); c00083_3300023.. (original name was: 3300023201.a:Ga0256614_1473203); c00085_3300023.. (original name was: 3300023201.a:Ga0256614_1086813); c00086_3300023.. (original name was: 3300023201.a:Ga0256614_1084011); c00087_3300023.. (original name was: 3300023201.a:Ga0256614_1123241); c00088_3300023.. (original name was: 3300023201.a:Ga0256614_1176658); c00089_3300023.. (original name was: 3300023201.a:Ga0256614_1223557); c00090_3300023.. (original name was: 3300023201.a:Ga0256614_1145535); c00091_3300023.. (original name was: 3300023201.a:Ga0256614_1281835); c00092_3300023.. (original name was: 3300023201.a:Ga0256614_1377305); c00093_3300023.. (original name was: 3300023201.a:Ga0256614_1006643); c00094_3300023.. (original name was: 3300023201.a:Ga0256614_1083072); c00096_3300023.. (original name was: 3300023201.a:Ga0256614_1064713); c00097_3300023.. (original name was: 3300023201.a:Ga0256614_1110159); c00098_3300023.. (original name was: 3300023201.a:Ga0256614_1225680); c00099_3300023.. (original name was: 3300023201.a:Ga0256614_1062407); c00100_3300023.. (original name was: 3300023201.a:Ga0256614_1342693); c00101_3300023.. (original name was: 3300023201.a:Ga0256614_1147107); c00102_3300023.. (original name was: 3300023201.a:Ga0256614_1163467); c00103_3300023.. (original name was: 3300023201.a:Ga0256614_1176907)

Compact view

c00008_3300023.. - Region 1 - NRPS-like

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Location: 55,069 - 77,347 nt. (total: 22,279 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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core biosynthetic genes

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

c00009_3300023.. - Region 1 - bacteriocin

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Location: 475 - 11,356 nt. (total: 10,882 nt) Show pHMM detection rules used

bacteriocin: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or TIGR01193)

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core biosynthetic genes

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c00010_3300023.. - Region 1 - bacteriocin

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Location: 45,540 - 55,761 nt. (total: 10,222 nt) Show pHMM detection rules used

bacteriocin: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or TIGR01193)

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core biosynthetic genes

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c00016_3300023.. - Region 1 - terpene

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Location: 1 - 11,304 nt. (total: 11,304 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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core biosynthetic genes

additional biosynthetic genes

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resistance

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c00021_3300023.. - Region 1 - NRPS,T1PKS

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Location: 1 - 80,486 nt. (total: 80,486 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 80486:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly) + (ohmal) + (D-X) + (D-thr - val) + (X) + (ile - ala) + (redmal) + (ccmal) + (ohmal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 0 - 56291:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly) + (ohmal) + (D-X) + (D-thr - val) + (X) + (ile - ala) + (redmal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 29249 - 80486:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ohmal) + (ccmal) + (redmal) + (ile - ala)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg21_1

Search NORINE for peptide: strict or relaxed

AMP-binding (998..1385): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGVvWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 90% (moderate)

ctg21_2

PKS_AT (532..824): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 83.3%; 2-Rhyd-Malonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 145.4
inactive: 94.6
Methoxymalonyl-CoA: 53.0
Methylmalonyl-CoA: 46.1
Propionyl-CoA: 37.2
fatty_acid: 16.9
Isobutyryl-CoA: 14.8
Ethylmalonyl-CoA: 13.2
CHC-CoA: 11.1
2-Methylbutyryl-CoA: 10.8
trans-1,2-CPDA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

ctg21_3

Search NORINE for peptide: strict or relaxed

AMP-binding (533..928): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: orn, lys, arg
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAQDiGVVDK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 90% (moderate)

ctg21_5

Search NORINE for peptide: strict or relaxed

AMP-binding (466..866): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNVGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

AMP-binding (1968..2361): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAFWlGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 90% (moderate)

ctg21_7

Search NORINE for peptide: strict or relaxed

AMP-binding (479..885): X

NRPSPredictor2: asp, asn, glu, gln, aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DlknFGSdvK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 50% (weak)

ctg21_8

Search NORINE for peptide: strict or relaxed

AMP-binding (506..905): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: ile

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGVsFK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 90% (moderate)

AMP-binding (1560..1947): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: DLFNNALTYK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 100% (strong)

ctg21_21

PKS_AT (1302..1595): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 79.2%; Propionyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 153.0
inactive: 100.5
Methylmalonyl-CoA: 54.3
Methoxymalonyl-CoA: 51.5
Propionyl-CoA: 43.5
Isobutyryl-CoA: 21.9
Ethylmalonyl-CoA: 17.9
CHC-CoA: 17.6
Benzoyl-CoA: 15.4
2-Methylbutyryl-CoA: 15.1
Acetyl-CoA: 10.0
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0

ctg21_22

PKS_AT (559..848): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; inactive: 62.5%; Methylmalonyl-CoA: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 143.6
inactive: 64.0
Methylmalonyl-CoA: 58.6
Methoxymalonyl-CoA: 52.3
Propionyl-CoA: 39.9
Benzoyl-CoA: 23.8
fatty_acid: 20.6
CHC-CoA: 20.5
Isobutyryl-CoA: 15.0
3-Methylbutyryl-CoA: 14.9
2-Methylbutyryl-CoA: 14.7
Acetyl-CoA: 14.2
Ethylmalonyl-CoA: 12.2
trans-1,2-CPDA: 9.3

ctg21_23

PKS_AT (557..841): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; inactive: 58.3%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 127.3
inactive: 84.8
Methylmalonyl-CoA: 55.4
Methoxymalonyl-CoA: 51.1
Propionyl-CoA: 39.9
Isobutyryl-CoA: 27.0
Benzoyl-CoA: 23.9
2-Methylbutyryl-CoA: 15.2
CHC-CoA: 14.2
Acetyl-CoA: 12.9
fatty_acid: 12.2
3-Methylbutyryl-CoA: 9.2
trans-1,2-CPDA: 0.0
Ethylmalonyl-CoA: 0.0

c00047_3300023.. - Region 1 - terpene

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Location: 72,885 - 94,858 nt. (total: 21,974 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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core biosynthetic genes

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c00049_3300023.. - Region 1 - hserlactone

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Location: 56,922 - 77,659 nt. (total: 20,738 nt) Show pHMM detection rules used

hserlactone: Autoind_synth

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core biosynthetic genes

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c00049_3300023.. - Region 2 - NRPS,T1PKS

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Location: 91,264 - 129,090 nt. (total: 37,827 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 91263 - 129090:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ccmal) + (ccmal) + (ccmal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 107201 - 129090:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ccmal) + (ccmal) + (ccmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg49_98

PKS_AT (557..838): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; inactive: 58.3%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 141.5
inactive: 94.4
Methylmalonyl-CoA: 67.9
Methoxymalonyl-CoA: 64.2
Propionyl-CoA: 56.3
Ethylmalonyl-CoA: 36.5
2-Methylbutyryl-CoA: 34.7
Acetyl-CoA: 31.8
Isobutyryl-CoA: 27.4
CHC-CoA: 22.0
Benzoyl-CoA: 20.4
fatty_acid: 16.8
3-Methylbutyryl-CoA: 11.4
trans-1,2-CPDA: 9.0

ctg49_99

PKS_AT (562..851): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 83.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 148.3
inactive: 91.7
Methoxymalonyl-CoA: 47.5
Methylmalonyl-CoA: 41.0
Propionyl-CoA: 24.2
Isobutyryl-CoA: 18.1
CHC-CoA: 15.7
2-Methylbutyryl-CoA: 15.5
Acetyl-CoA: 14.2
Benzoyl-CoA: 13.3
Ethylmalonyl-CoA: 9.0
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0

ctg49_100

PKS_AT (566..848): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; inactive: 66.7%; Propionyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 149.9
inactive: 98.9
Methylmalonyl-CoA: 59.4
Methoxymalonyl-CoA: 52.2
Propionyl-CoA: 31.0
Benzoyl-CoA: 26.5
Ethylmalonyl-CoA: 19.6
2-Methylbutyryl-CoA: 17.3
CHC-CoA: 14.8
Acetyl-CoA: 13.9
Isobutyryl-CoA: 13.2
fatty_acid: 12.5
trans-1,2-CPDA: 12.4
3-Methylbutyryl-CoA: 0.0

c00050_3300023.. - Region 1 - NRPS

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Location: 74,026 - 128,768 nt. (total: 54,743 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 74025 - 128768:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal - X) + (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg50_91

Search NORINE for peptide: strict or relaxed

AMP-binding (521..919): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DiEnVGTviK
Nearest Stachelhaus code:: lys-b
Stachelhaus code match:: 60% (weak)

ctg50_92

Search NORINE for peptide: strict or relaxed

AMP-binding (1127..1525): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DiEnvGSViK
Nearest Stachelhaus code:: lys
Stachelhaus code match:: 60% (weak)

ctg50_96

Search NORINE for peptide: strict or relaxed

AMP-binding (14..422): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: hmWpLGinmK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 40% (weak)

c00052_3300023.. - Region 1 - NRPS

Download region GenBank file

Location: 1 - 3,207 nt. (total: 3,207 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

c00074_3300023.. - Region 1 - hserlactone

Download region GenBank file

Location: 1 - 20,749 nt. (total: 20,749 nt) Show pHMM detection rules used

Region on contig edge.

hserlactone: Autoind_synth

Legend:

core biosynthetic genes

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Gene details

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c00078_3300023.. - Region 1 - arylpolyene

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Location: 1 - 39,790 nt. (total: 39,790 nt) Show pHMM detection rules used

Region on contig edge.

arylpolyene: (APE_KS1 or APE_KS2)

Legend:

core biosynthetic genes

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Gene details

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c00084_3300023.. - Region 1 - bacteriocin

Download region GenBank file

Location: 40,520 - 51,371 nt. (total: 10,852 nt) Show pHMM detection rules used

bacteriocin: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

c00095_3300023.. - Region 1 - NRPS

Download region GenBank file

Location: 1 - 19,486 nt. (total: 19,486 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 19486:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X) + (ser)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg95_2

Search NORINE for peptide: strict or relaxed

AMP-binding (503..908): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHlSLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 90% (moderate)

ctg95_4

Search NORINE for peptide: strict or relaxed

CAL_domain (54..499): pk

minowa: Acetyl-CoA

Prediction, score:

Acetyl-CoA: 48.4
fatty_acid: 36.2
NH2: 17.7
AHBA: 11.9
shikimic_acid: 0.0

AMP-binding (1190..1588): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DSaLiAEVwK
Nearest Stachelhaus code:: his
Stachelhaus code match:: 70% (weak)