LOCUS       c00160_3300023..        6499 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300023267.a:Ga0247771_1001905.
ACCESSION   c00160_3300023..
VERSION     c00160_3300023..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 15:23:16
            Original ID  :: 3300023267.a:Ga0247771_1001905
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6499
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6499
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:6498]"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..6498
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..6499
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6499
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             2..2410
                     /NRPS_PKS="Domain: PCP (284-350). E-value: 7.8e-22. Score:
                     69.0. Matches aSDomain: nrpspksdomains_ctg160_1_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (361-659). E-value:
                     2.5e-91. Score: 298.3. Matches aSDomain:
                     nrpspksdomains_ctg160_1_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (672-798). E-value: 2.3e-28.
                     Score: 90.7. Matches aSDomain:
                     nrpspksdomains_ctg160_1_TIGR01720.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     177.1; E-value: 8e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg160_1"
                     /sec_met_domain="Condensation (E-value: 1.1e-59, bitscore:
                     190.4, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3.2e-56, bitscore:
                     179.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 5.1e-14, bitscore:
                     41.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="NEHGVQVCDATPMHLDILGGEEVQPRASSLIAFLCGGQQLLTRTV
                     ERLRSRLGSTLEVVNVYGPTECCVNATAFRMDEHTLSATTAVPIGQPLPNTHIYIVDAA
                     QRPVPVGIVGEIFIGGHGVARGYTGRPELTSERFIEYSLTGERVYRTGDLARRRTDGNI
                     EFVGRADEQVKIRGYRIELDEIREKLIAIGKIRDCALAVKKDRNGNDMIVAYLVTLQNI
                     GLSELTSTLRSSLPDYMIPAWFVRLRKIPVSLNGKIRKDELPQPEGIAIQAEARYEAPR
                     NVVEQKLVEIFEDILGRQNIGIHDNFYETGGDSIKAVQMSGRLYRIGYKVDVRELFLNP
                     TIAGLATKVTEIEENSDQAFLTGPARMAPIQAHYFSQPDTEMNHFNQSICFHSEDRLNA
                     ADVQVIFQKLLEHHDELRAVFIPEGAGVRQEITGLPDRLDVAELHLEQLEETEAERLFE
                     EKTYEWQGSMKLDEGPLMRLALVHMKDEDRLLVIIHHLVTDGFSWRILFEDIGILFRQS
                     REGGKLELPLKTDSYKLWAETLYTRANSEPFLSRAAYWKKLSALDLPIIPKDQQEDTCY
                     NYNTKSVQASLSKEMSTALISDVNQAYGTETNEILLSAFGMAVNESFGMERVGVYMVGH
                     GRDETVTGLNISRTVGWFNIIYPFVVNVSGSSDHLDIVGQVKSDARAVPDKGFGYSILK
                     FLTEPEHKKDFEDRLRPNIMFNYLGQFDTDVKNLSFSVENIHDSAIGRNRRQRFELIVS
                     SILANGRLSIGIQYNDRQYSQSVMEKLLAAYMEKLELLIQPCLTETQPA"
     CDS_motif       326..415
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg160_1_0001"
                     /evalue="1.70E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg160_1"
                     /protein_end="138"
                     /protein_start="108"
                     /score="49.1"
                     /tool="antismash"
                     /translation="PVGIVGEIFIGGHGVARGYTGRPELTSERFI"
     CDS_motif       494..556
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg160_1_0002"
                     /evalue="4.50E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg160_1"
                     /protein_end="185"
                     /protein_start="164"
                     /score="34.7"
                     /tool="antismash"
                     /translation="FVGRADEQVKIRGYRIELDEIR"
     aSDomain        854..1051
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg160_1_PCP.1"
                     /evalue="7.80E-22"
                     /label="ctg160_1_PCP.1"
                     /locus_tag="ctg160_1"
                     /protein_end="350"
                     /protein_start="284"
                     /score="69.0"
                     /tool="antismash"
                     /translation="EQKLVEIFEDILGRQNIGIHDNFYETGGDSIKAVQMSGRLYRIGY
                     KVDVRELFLNPTIAGLATKVTE"
     aSModule        854..1978
                     /domains="nrpspksdomains_ctg160_1_PCP.1"
                     /domains="nrpspksdomains_ctg160_1_Epimerization.1"
                     /incomplete
                     /locus_tags="ctg160_1"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        1085..1978
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg160_1_Epimerization.1"
                     /evalue="2.50E-91"
                     /label="ctg160_1_Epimerization.1"
                     /locus_tag="ctg160_1"
                     /protein_end="659"
                     /protein_start="361"
                     /score="298.3"
                     /tool="antismash"
                     /translation="TGPARMAPIQAHYFSQPDTEMNHFNQSICFHSEDRLNAADVQVIF
                     QKLLEHHDELRAVFIPEGAGVRQEITGLPDRLDVAELHLEQLEETEAERLFEEKTYEWQ
                     GSMKLDEGPLMRLALVHMKDEDRLLVIIHHLVTDGFSWRILFEDIGILFRQSREGGKLE
                     LPLKTDSYKLWAETLYTRANSEPFLSRAAYWKKLSALDLPIIPKDQQEDTCYNYNTKSV
                     QASLSKEMSTALISDVNQAYGTETNEILLSAFGMAVNESFGMERVGVYMVGHGRDETVT
                     GLNISRTVGWFNIIYPFV"
     CDS_motif       1226..1273
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg160_1_0003"
                     /evalue="1.20E-03"
                     /label="Cy2"
                     /locus_tag="ctg160_1"
                     /protein_end="424"
                     /protein_start="408"
                     /score="11.6"
                     /tool="antismash"
                     /translation="LLEHHDELRAVFIPEGA"
     CDS_motif       1466..1531
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg160_1_0004"
                     /evalue="4.30E-10"
                     /label="NRPS-E2"
                     /locus_tag="ctg160_1"
                     /protein_end="510"
                     /protein_start="488"
                     /score="31.8"
                     /tool="antismash"
                     /translation="LLVIIHHLVTDGFSWRILFEDIG"
     CDS_motif       1934..1984
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg160_1_0005"
                     /evalue="2.70E-06"
                     /label="NRPS-E5"
                     /locus_tag="ctg160_1"
                     /protein_end="661"
                     /protein_start="644"
                     /score="19.7"
                     /tool="antismash"
                     /translation="NISRTVGWFNIIYPFVVN"
     aSDomain        2018..2395
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg160_1_TIGR01720.1"
                     /evalue="2.30E-28"
                     /label="ctg160_1_TIGR01720.1"
                     /locus_tag="ctg160_1"
                     /protein_end="798"
                     /protein_start="672"
                     /score="90.7"
                     /tool="antismash"
                     /translation="VGQVKSDARAVPDKGFGYSILKFLTEPEHKKDFEDRLRPNIMFNY
                     LGQFDTDVKNLSFSVENIHDSAIGRNRRQRFELIVSSILANGRLSIGIQYNDRQYSQSV
                     MEKLLAAYMEKLELLIQPCLTET"
     CDS_motif       2027..2089
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg160_1_0006"
                     /evalue="4.10E-06"
                     /label="NRPS-E6"
                     /locus_tag="ctg160_1"
                     /protein_end="696"
                     /protein_start="675"
                     /score="19.3"
                     /tool="antismash"
                     /translation="VKSDARAVPDKGFGYSILKFLT"
     CDS             2438..3274
                     /locus_tag="ctg160_2"
                     /transl_table=11
                     /translation="MATSIKTAGKTSAERIVSNFMSFSPADLAELAEAIREGRYFFELH
                     ANDDGVQPMGAFDFLFGNEFYQHSLDDAAAYWEYVLLCFVNGRGEEVKTPVSIYGVSPA
                     RKVRTALITLHTLSQLVKVNEKDAHLMIAFSNDEEFSQAWQLFNARKFTLMHRLFEFYF
                     GLGDGYVSSLDWRVRHKGNLTREAAEIIADIVRYEDPETQIEYYYNAPADGGIEGYLRD
                     TFARKSWLYNQYDVGIVTKTPFESYPPAVFRAVQEFYRCLILPGGECAPLQETTGP"
     CDS             3291..4001
                     /NRPS_PKS="Domain: Thioesterase (5-222). E-value: 7.5e-37.
                     Score: 119.6. Matches aSDomain:
                     nrpspksdomains_ctg160_3_Thioesterase.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004:thioesterase (Score: 206.1; E-value: 7.1e-63)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg160_3"
                     /sec_met_domain="Abhydrolase_6 (E-value: 4.9e-14, bitscore:
                     41.9, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 5.4e-08, bitscore: 21.1,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKHLLICLPFAGGSKYSMRFLEPLLPRHIACYFVEYAGHGGRNR
                     EPFSESMEALVDDLYGIVSPLIDDTYSIYGHSMGATVACLLARKIRKEGRPLPQHVIVS
                     GTDGPSVPPRSAPKHLMPRDEFLAAIRKLGGLPDEILEDQELLEYFEPVLRADFKVIEE
                     FSYQSGERLNIPFTVVVGDEEDMSDEDVLQWQRETSVPVRVFKLPGNHFFIYEQGKELA
                     YIIGRAAEPLTGSR"
     aSDomain        3306..3956
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg160_3_Thioesterase.1"
                     /evalue="7.50E-37"
                     /label="ctg160_3_Thioesterase.1"
                     /locus_tag="ctg160_3"
                     /protein_end="222"
                     /protein_start="5"
                     /score="119.6"
                     /tool="antismash"
                     /translation="LICLPFAGGSKYSMRFLEPLLPRHIACYFVEYAGHGGRNREPFSE
                     SMEALVDDLYGIVSPLIDDTYSIYGHSMGATVACLLARKIRKEGRPLPQHVIVSGTDGP
                     SVPPRSAPKHLMPRDEFLAAIRKLGGLPDEILEDQELLEYFEPVLRADFKVIEEFSYQS
                     GERLNIPFTVVVGDEEDMSDEDVLQWQRETSVPVRVFKLPGNHFFIYEQGKELAY"
     aSModule        3306..3956
                     /domains="nrpspksdomains_ctg160_3_Thioesterase.1"
                     /final_module
                     /incomplete
                     /locus_tags="ctg160_3"
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       3501..3554
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg160_3_0001"
                     /evalue="2.10E-05"
                     /label="NRPS-te1"
                     /locus_tag="ctg160_3"
                     /protein_end="88"
                     /protein_start="70"
                     /score="17.0"
                     /tool="antismash"
                     /translation="YSIYGHSMGATVACLLARK"
     CDS             4024..4881
                     /locus_tag="ctg160_4"
                     /transl_table=11
                     /translation="MTHNPIAARLKELYPGLRYMDTCTAPTYEEFNTRYGHASVPVLVR
                     GVASQWKAMERWNIPEFLRNVPRREVGVSRTDESEPVRMDIHEFFNYMSGSEDNPYYLR
                     DWRFDKDCPAMLDDYEVPRYFESWAQRLPDGMRPELRWLYVGPDNSGTGLHLDTMDTSA
                     WNAVITGRKHWLFFTREDGPRLYNGHADMFRPDFDRFPLTKGLSPIYCVQEPGEIVFTP
                     STWWHQVYNEKGGISITENFVNETNYRQVEDFFIANRQPEKLEIFRRLRASVTDTAAGT
                     PINE"
     CDS             4885..6498
                     /NRPS_PKS="Domain: Condensation_Starter (12-302). E-value:
                     1.5e-76. Score: 249.3. Matches aSDomain:
                     nrpspksdomains_ctg160_5_Condensation_Starter.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     285.6; E-value: 1.4e-86)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg160_5"
                     /sec_met_domain="Condensation (E-value: 5.2e-53, bitscore:
                     168.4, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.4e-09, bitscore:
                     24.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVSATTLHKDEHYYELAHPQKRVWYVEQTGGGTPLFTLGGTVLF
                     SAAVDMDALQESIRRCVNGHDAFRLRISAHEARQYLAPPSDAVFPLFDFSAQPDGQAAF
                     EQWAQQELRTPFVLADGPLYDFKLFRLPGGREGFIIKVHHIVLDGWSISLVTDRIYTYY
                     RLIKGLSDEAAVAAPSYLAFVQEESDYLASPAAAADRAYWLDQFRDLPDTAKLNLDGPQ
                     AGGRKNYVLEEGMTSRLKEFLKQTESSPNLFYTALVALYLYKTTGRDDLVIGIPVANRR
                     SKRDKQTVGMFTSTMPLRIRLNKQESFRQLLDRLRRQLRASYARQRYPYDRLVQDLGLG
                     RSGYNSLFGVCVNYYNTAHATRLGNALVENIEYYSGTQYYPLQLVVKEWLDTPNLQLQF
                     DYTTADYSDAKIDAIKNVLDHFTALVLEDDGREIGGMDLLDAPSFALLVQDFNKPVQTP
                     RFSDKTVLSLFSEGLPHYRRNTVIINGAETWTYDYFDRQAEALAALLMDKGLAAGDRVA
                     IVSARDGYYVLAVWAVLRAGG"
     aSDomain        4921..5790
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg160_5_Condensation_Starter.1"
                     /domain_subtype="Condensation_Starter"
                     /evalue="1.50E-76"
                     /label="ctg160_5_Condensation_Starter.1"
                     /locus_tag="ctg160_5"
                     /protein_end="302"
                     /protein_start="12"
                     /score="249.3"
                     /tool="antismash"
                     /translation="HYYELAHPQKRVWYVEQTGGGTPLFTLGGTVLFSAAVDMDALQES
                     IRRCVNGHDAFRLRISAHEARQYLAPPSDAVFPLFDFSAQPDGQAAFEQWAQQELRTPF
                     VLADGPLYDFKLFRLPGGREGFIIKVHHIVLDGWSISLVTDRIYTYYRLIKGLSDEAAV
                     AAPSYLAFVQEESDYLASPAAAADRAYWLDQFRDLPDTAKLNLDGPQAGGRKNYVLEEG
                     MTSRLKEFLKQTESSPNLFYTALVALYLYKTTGRDDLVIGIPVANRRSKRDKQTVGMFT
                     STMPLRIRLN"
     aSModule        4921..5790
                     /domains="nrpspksdomains_ctg160_5_Condensation_Starter.1"
                     /incomplete
                     /locus_tags="ctg160_5"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       4987..5100
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg160_5_0001"
                     /evalue="8.00E-09"
                     /label="C2_starter_024-063"
                     /locus_tag="ctg160_5"
                     /protein_end="72"
                     /protein_start="34"
                     /score="28.1"
                     /tool="antismash"
                     /translation="PLFTLGGTVLFSAAVDMDALQESIRRCVNGHDAFRLRIS"
     CDS_motif       5308..5373
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg160_5_0002"
                     /evalue="1.40E-08"
                     /label="C3_starter_134-155"
                     /locus_tag="ctg160_5"
                     /protein_end="163"
                     /protein_start="141"
                     /score="27.5"
                     /tool="antismash"
                     /translation="VHHIVLDGWSISLVTDRIYTYYR"
     CDS_motif       5692..5781
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg160_5_0003"
                     /evalue="2.60E-12"
                     /label="C5_starter_265-294"
                     /locus_tag="ctg160_5"
                     /protein_end="299"
                     /protein_start="269"
                     /score="39.0"
                     /tool="antismash"
                     /translation="DLVIGIPVANRRSKRDKQTVGMFTSTMPLRI"
     CDS_motif       5830..5946
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg160_5_0004"
                     /evalue="4.60E-13"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="ctg160_5"
                     /protein_end="354"
                     /protein_start="315"
                     /score="41.6"
                     /tool="antismash"
                     /translation="RRQLRASYARQRYPYDRLVQDLGLGRSGYNSLFGVCVNYY"
     CDS_motif       6196..6237
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg160_5_0005"
                     /evalue="1.60E+00"
                     /label="C3_DCL_135-156"
                     /locus_tag="ctg160_5"
                     /protein_end="451"
                     /protein_start="437"
                     /score="1.7"
                     /tool="antismash"
                     /translation="LLDAPSFALLVQDFN"
ORIGIN
        1 caatgagcac ggcgtacagg tatgcgatgc cacacccatg catctggata tactgggcgg
       61 cgaggaagta cagccgcgcg cctcatcgct catcgctttt ctctgcggcg gccagcaatt
      121 gctgacgcgc accgtggagc gcctccgctc gcgcctgggc agcacgctcg aagtggtgaa
      181 cgtatacggc cccaccgaat gctgcgtgaa cgcaacggct ttccgcatgg acgagcacac
      241 gctctccgcc acgaccgccg ttcccatcgg gcagcccctg ccgaacacgc atatttatat
      301 cgttgatgcg gcgcagcgcc ccgtgcctgt gggcatagtg ggtgagatct tcatcggcgg
      361 acatggcgtg gcccgcggct ataccggccg ccccgagctc acctccgaac gcttcatcga
      421 gtactccctt accggcgagc gtgtttaccg caccggcgac cttgcacgcc gtcgcaccga
      481 cggcaatatc gagttcgtcg gccgcgctga cgagcaggta aagatccgcg gctaccgcat
      541 tgagctggac gagatcaggg aaaagctgat agccatcggc aagatcaggg attgcgcgct
      601 ggcggtgaaa aaggaccgca acgggaacga tatgatcgtg gcctacctgg ttacgctgca
      661 gaacatcggt ctctcggaac tcacgtccac actgcgttcc agcctgccgg actatatgat
      721 cccggcctgg ttcgtgcgtt tgcgcaagat acccgtttcg ctgaacggca agatcaggaa
      781 ggacgagctg ccccaacccg aaggcatcgc catacaggcc gaagcgcgct acgaagcgcc
      841 gcgcaacgtc gtggagcaaa agctggttga gatcttcgaa gacatcctcg gccggcagaa
      901 catcggcatc cacgataatt tttacgagac cggcggcgat tccatcaagg ccgtgcaaat
      961 gtccggcagg ctgtatcgca tcggttacaa ggtagatgtg cgcgagctct tcctcaaccc
     1021 caccattgcc ggcctggcca caaaggtgac ggagatcgaa gagaactccg accaggcctt
     1081 cctcaccggc cccgcccgca tggcgcctat tcaggcccac tacttttcgc agcccgatac
     1141 ggagatgaac catttcaacc aatccatctg cttccatagc gaggacaggc tgaatgcagc
     1201 cgatgtacag gttatctttc aaaagctgct cgaacaccac gacgagctgc gtgccgtatt
     1261 tataccggaa ggcgccggcg tgcgacagga gatcaccggc ctcccggacc gactggacgt
     1321 agccgagctg cacctggaac aattggagga aaccgaggcc gaacgcctgt tcgaggaaaa
     1381 gacctacgag tggcagggct caatgaagct cgacgaaggt ccgctgatgc ggctcgcgct
     1441 cgtgcacatg aaggacgaag accgcctgct cgtcatcatc catcacctgg tgacggacgg
     1501 cttctcatgg cgcattcttt tcgaggacat tggcattctg ttccgccagt cgcgcgaggg
     1561 gggcaaactg gagctgccgc tgaaaacgga ctcgtacaag ctgtgggccg aaacccttta
     1621 tacgcgcgcc aacagcgagc ctttcctctc gcgggcagcg tactggaaaa aactgtcggc
     1681 cctcgacctg ccgatcatcc cgaaagatca gcaggaagat acctgctaca actacaatac
     1741 gaagtccgtg caggcttcgc tcagcaagga aatgtccacg gccctcatca gcgacgttaa
     1801 ccaggcttac ggaacggaaa cgaacgagat actgctgtcg gccttcggca tggcggtgaa
     1861 cgaatcgttc ggcatggagc gcgtgggcgt ttacatggtc ggccacggcc gcgacgaaac
     1921 ggtaacaggc ctgaacatca gccgcaccgt gggttggttc aacatcatct atcccttcgt
     1981 ggtcaatgtt tccggaagca gcgatcacct cgatatcgtc ggccaggtaa agagcgatgc
     2041 gcgtgcggtg cccgacaagg gcttcggcta cagcatcctt aaattcctga ccgagcccga
     2101 acacaaaaag gatttcgagg accgcctgcg gcccaacatc atgttcaact acctgggcca
     2161 gttcgatacg gacgtgaaga atctttcttt ctccgtggag aatattcacg acagcgcgat
     2221 cggccgcaac cgccgccagc gttttgagct gatcgtcagc tcgatcctgg ccaacggccg
     2281 cctgtccatc ggcatccagt acaacgaccg gcagtacagc cagtccgtga tggaaaagct
     2341 gctggccgct tacatggaaa agctggagct gctgatccag ccctgcctca ccgaaaccca
     2401 gcccgcataa gggttcttta tgactaaaca aacacacatg gcgacgtcga taaaaaccgc
     2461 tggtaaaaca agtgccgaac ggatcgtttc gaacttcatg agcttttcgc cggcagacct
     2521 tgcggagctg gcggaggcca tccgcgaagg gcgctatttc ttcgagctgc acgccaacga
     2581 cgacggcgtg cagcccatgg gcgccttcga ttttcttttc ggcaatgagt tctaccaaca
     2641 ttcgctcgac gacgcggcgg cctattggga atatgtcctt ctgtgctttg tgaacggcag
     2701 gggcgaggag gtaaagacac cggtctcgat ctacggcgtg agcccggcgc gcaaggtgcg
     2761 tacggcgctg atcacgctgc ataccctgtc gcagctggtg aaggtgaacg agaaggatgc
     2821 ccacctcatg atcgccttca gcaacgacga agagtttagt caggcctggc agctcttcaa
     2881 cgcaaggaag ttcaccctca tgcaccgcct ctttgaattt tacttcggcc tcggcgacgg
     2941 ttatgtatcg tcgctggact ggcgcgtgcg ccacaagggc aacctcacgc gcgaagcggc
     3001 cgagatcatt gcggacatcg ttcgctacga agaccccgaa acgcagatcg aatattatta
     3061 caacgcgccg gccgacggcg ggatcgaagg ttaccttcgc gataccttcg cacgcaaaag
     3121 ctggctttac aaccagtacg atgtcggcat cgtgacgaaa acaccgttcg aaagctatcc
     3181 ccctgcggtc ttccgggccg tacaggaatt ttaccgatgc ctcatcctgc cgggcggcga
     3241 atgcgcaccc ctgcaggaaa ccaccggccc ttaagcaaaa actgtatcac atgcaaaagc
     3301 atctgcttat ctgcctgccc tttgccggcg gctcgaaata ttccatgcgc ttcctagagc
     3361 ccttgctgcc ccggcatatc gcttgctatt tcgttgagta tgccgggcac ggcgggcgca
     3421 accgcgaacc tttttccgaa agcatggaag ccctcgtcga tgacctgtac ggtatcgtgt
     3481 cgccgcttat tgacgatacc tattccatct acggacacag catgggcgct acggtggcct
     3541 gcctgctcgc gcgcaagatc cgcaaggagg gaagacccct gccgcagcac gtcatcgtat
     3601 cgggtactga tggcccgtca gtgccgccgc gctcggctcc caagcacctc atgccccgcg
     3661 acgaatttct tgcagcgatc agaaagctgg gcggactgcc cgatgagata ctggaagacc
     3721 aggagctgct cgaatacttc gaacccgtgc tgcgcgcgga tttcaaggtc atcgaggaat
     3781 tcagctatca gtccggcgag cggctgaata ttccctttac tgtagtggta ggcgacgaag
     3841 aggatatgtc cgacgaagac gtgctgcaat ggcagcgcga aacatcggtg ccggtccgcg
     3901 tcttcaagct gcccggcaac cattttttca tttatgaaca gggcaaggag ctggcttata
     3961 tcatcggccg cgccgccgaa cctctaacag gatcccgcta acccctcaac actcatcacc
     4021 actatgacgc acaacccgat cgccgcacga ctgaaagagc tataccccgg attgcggtac
     4081 atggatacct gcaccgcgcc gacatacgaa gagttcaata cccgctacgg tcatgcctcc
     4141 gtgcccgtgc tggtccgcgg cgtagcctcg caatggaagg ccatggaacg ctggaacata
     4201 ccggaatttc tgcgcaatgt tccgcgccgc gaagtggggg tatcgcgcac cgatgagtcg
     4261 gagccggtgc ggatggacat tcatgaattt tttaactata tgtccggcag cgaagacaac
     4321 ccctactacc tgcgcgactg gcgcttcgac aaggactgcc cggccatgct cgacgattac
     4381 gaggtgcccc gctattttga aagctgggcg caacgcctgc ccgacggcat gaggcccgag
     4441 ctgcgctggc tctatgtagg ccccgacaat tccggcaccg gcctgcacct cgatacgatg
     4501 gacaccagcg cgtggaatgc agtcatcacc ggccgcaagc actggctctt ctttacccgc
     4561 gaggacggcc cccgactgta caacggacac gccgatatgt tccggccgga cttcgaccgc
     4621 tttcctctta caaagggact gtcgccaatc tattgcgtgc aggaaccggg cgagatcgtg
     4681 ttcacgccct ctacctggtg gcaccaggtg tataatgaaa aaggcggcat ttccattacc
     4741 gaaaactttg tgaacgaaac gaactaccgg caggtggaag attttttcat tgccaacagg
     4801 caacccgaaa agctcgagat ctttcgccgc ctccgtgcgt cggtgacgga cacggctgcc
     4861 ggcacgccga tcaacgaata aagcatgctt gtgagcgcaa caactttaca taaagacgaa
     4921 cattattacg agctcgctca cccgcaaaag cgcgtgtggt atgtagagca gaccggtggc
     4981 ggcacgccgc tcttcacgct tggcggcacg gtgctgtttt ccgctgccgt cgatatggat
     5041 gcgctgcagg agtcgatccg ccgctgcgtg aacgggcacg atgctttccg cctccgcatt
     5101 tccgcgcacg aggcaaggca atatcttgcg cctccgtccg atgcagtctt tcccctcttt
     5161 gatttttcgg cgcagccaga tgggcaggca gctttcgaac agtgggcgca gcaggagctc
     5221 cggacgcctt ttgttctggc agacggacca ctatacgact tcaagctttt ccggctgccc
     5281 ggtggccgcg aaggcttcat catcaaggtt catcacatcg tgcttgacgg ctggtcgatc
     5341 tcgctcgtga ccgaccgtat ttatacgtat taccggctga tcaaaggtct ttcggatgaa
     5401 gctgccgtcg ctgcgccttc gtacctggcc tttgtgcagg aagaaagcga ctacctcgca
     5461 tcgcccgctg ccgcagcgga ccgcgcttac tggctcgacc agttccgcga ccttcccgat
     5521 accgcaaagc tcaacctcga cggacctcag gccgggggcc gaaagaacta tgtgctggaa
     5581 gaagggatga cgagccggct gaaagaattt ctcaaacaaa ccgaaagctc gcccaatctt
     5641 ttttatacgg ccctggtggc cctctacctg tacaagacca caggccgcga cgaccttgtg
     5701 atcggcatac ctgtggccaa ccggcgctct aagcgtgaca agcaaaccgt gggcatgttc
     5761 acgagcacga tgccgctgcg catccggcta aacaagcagg agagcttccg ccaactgctg
     5821 gaccgcctac gccgccagct acgcgcgagc tatgcccgcc agcgctatcc ctacgaccgc
     5881 ctggtgcagg acctcgggct tggaagatcg ggctacaaca gccttttcgg ggtttgcgtc
     5941 aattactaca atacggctca tgccacgcgc ctcggcaatg cgctggtaga gaatatcgaa
     6001 tactacagcg gcacgcaata ctatccgctt cagctggtgg taaaggaatg gctcgatacg
     6061 ccgaacctgc aattgcagtt cgactatacc acggctgact atagcgacgc gaagatcgac
     6121 gccataaaaa atgtgctcga ccatttcacc gccctcgtgc tggaagacga tggccgggag
     6181 ataggaggga tggacctgct ggacgctcct tcgttcgcct tgctggtaca ggacttcaac
     6241 aagccggtgc aaacgccgcg cttcagcgat aagaccgtgc tttccctttt ttcggaaggc
     6301 ttgccgcact accgtagaaa tacggttatc atcaatgggg ctgaaacgtg gacctacgac
     6361 tatttcgacc ggcaggcaga agccctcgcc gcgctgctga tggacaaggg actggctgcg
     6421 ggcgatcgcg tagccatcgt atctgcgcgg gatggttact acgtgttggc agtatgggcg
     6481 gtgctgcgtg ccggcggcg
//
