LOCUS       c00228_3300023..        5550 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300023267.a:Ga0247771_1002612.
ACCESSION   c00228_3300023..
VERSION     c00228_3300023..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 15:23:16
            Original ID  :: 3300023267.a:Ga0247771_1002612
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5550
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5550
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2537:5549](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(2538..5549)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..5550
                     /SMILES="NC(C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5550
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             complement(36..275)
                     /NRPS_PKS="Domain: PP-binding (9-73). E-value: 1.8e-09.
                     Score: 29.8. Matches aSDomain:
                     nrpspksdomains_ctg228_1_PP-binding.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg228_1"
                     /sec_met_domain="PP-binding (E-value: 1e-10, bitscore:
                     29.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQEIASLIRENLLEIMPELNDEKFSDDDSFVELGANSIDRGELI
                     TLTLEKLNLDVPRIEFVSAQTIDQLAELMAEKSK"
     aSDomain        complement(57..248)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg228_1_PP-binding.1"
                     /evalue="1.80E-09"
                     /label="ctg228_1_PP-binding.1"
                     /locus_tag="ctg228_1"
                     /protein_end="73"
                     /protein_start="9"
                     /score="29.8"
                     /tool="antismash"
                     /translation="RENLLEIMPELNDEKFSDDDSFVELGANSIDRGELITLTLEKLNL
                     DVPRIEFVSAQTIDQLAELM"
     aSModule        57..248
                     /domains="nrpspksdomains_ctg228_1_PP-binding.1"
                     /incomplete
                     /locus_tags="ctg228_1"
                     /tool="antismash"
                     /type="unknown"
     CDS             complement(295..2541)
                     /NRPS_PKS="Domain: PKS_AT (4-276). E-value: 8.6e-56. Score:
                     181.2. Matches aSDomain: nrpspksdomains_ctg228_2_PKS_AT.1"
                     /NRPS_PKS="type: PKS/NRPS-like protein"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 460.3; E-value: 1.7e-139)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg228_2"
                     /sec_met_domain="PKS_AT (E-value: 5.1e-57, bitscore: 181.2,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVVVFPGQGSQYKGMGKDLFKLYPAETGRASALLGYDIEELCVS
                     DPARQLGKTQYTQPALYVVNALAWYSRQEPRPAYLAGHSLGEYNALLAAGAFDFETGLR
                     LVQKRGALMSAASGGAMAAVLGLSATAVRRKLDEGGYADIDVANYNTPTQTVVAGTQDG
                     IIRLVKELDAQGIRVVPLNVSAPFHSRYMQAAAEEFAAFLRSFSFSRLGIPVISNVTAR
                     PYGNDVADLLSRQIASPVQWTDTVRYLMGKGVSDFDEIGGSLLSKMVAEIRNDSTPVFD
                     EEKAEAAEYAPQQPAPATRAGRIGSSSFKSAYGIRYAYVAGSMYKGIASKEMVIRMGRA
                     GLLGFFGTGGLSFAEIEASIDSVQAALTQGEPYGFNLLHQFANPQREMKTVELYLRKGI
                     TRVEASAYIQITPALVYYRVKGLSKGADGSILCKHQVIAKVSRPEVAEAFLRPPPMKIV
                     NQLLEEGLITAEQAALSQQTPMSHDICVEADSGGHTDRGVALVLLPAIQQLRIRIAKEQ
                     GYDRPIHVGLAGGIGTPQAVACTFMMGADFVLTGSINQCTVEAGASNVVKDILQEINVQ
                     DTDYAPAGDMFEIGSKVQVLKKSVLFPARANKLFTLYNQYDSLEDIPGKVIRQIEDNYF
                     RRPLSTVWEDTKVHLRNRGAEATITTAEANAKQKMALVFKWYFHYSNRLALEGDTDDRV
                     NFQVHTGPALGSFNQWVKGTELESWRNRHVDAIGILLMEEAALLFEKTFQTIVN"
     aSDomain        complement(1714..2529)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg228_2_PKS_AT.1"
                     /evalue="8.60E-56"
                     /label="ctg228_2_PKS_AT.1"
                     /locus_tag="ctg228_2"
                     /protein_end="276"
                     /protein_start="4"
                     /score="181.2"
                     /specificity="consensus: mal"
                     /specificity="Minowa: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /tool="antismash"
                     /translation="VFPGQGSQYKGMGKDLFKLYPAETGRASALLGYDIEELCVSDPAR
                     QLGKTQYTQPALYVVNALAWYSRQEPRPAYLAGHSLGEYNALLAAGAFDFETGLRLVQK
                     RGALMSAASGGAMAAVLGLSATAVRRKLDEGGYADIDVANYNTPTQTVVAGTQDGIIRL
                     VKELDAQGIRVVPLNVSAPFHSRYMQAAAEEFAAFLRSFSFSRLGIPVISNVTARPYGN
                     DVADLLSRQIASPVQWTDTVRYLMGKGVSDFDEIGGSLLSKMVAEIRNDST"
     aSModule        1714..2529
                     /domains="nrpspksdomains_ctg228_2_PKS_AT.1"
                     /incomplete
                     /locus_tags="ctg228_2"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       complement(2200..2316)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg228_2_0002"
                     /evalue="3.00E-16"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ctg228_2"
                     /protein_end="114"
                     /protein_start="75"
                     /score="51.5"
                     /tool="antismash"
                     /translation="RPAYLAGHSLGEYNALLAAGAFDFETGLRLVQKRGALMSA"
     CDS_motif       complement(2482..2535)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg228_2_0001"
                     /evalue="1.60E-07"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="ctg228_2"
                     /protein_end="20"
                     /protein_start="2"
                     /score="23.4"
                     /tool="antismash"
                     /translation="VVVFPGQGSQYKGMGKDLF"
     CDS             complement(2538..5549)
                     /NRPS_PKS="Domain: AMP-binding (208-582). E-value:
                     2.8e-102. Score: 334.1. Matches aSDomain:
                     nrpspksdomains_ctg228_3_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (688-756). E-value: 1.5e-21. Score:
                     68.2. Matches aSDomain: nrpspksdomains_ctg228_3_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (777-997). E-value:
                     4.5e-23. Score: 74.6. Matches aSDomain:
                     nrpspksdomains_ctg228_3_Thioesterase.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     347.8; E-value: 1.4e-105)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg228_3"
                     /sec_met_domain="Condensation (E-value: 4.5e-12, bitscore:
                     33.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.6e-107, bitscore:
                     347.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6.3e-18, bitscore:
                     52.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LLHQYSGQEDICVGSPIANRTHPETEPLIGFFVNMLALRSEVRND
                     DSFTALLAQVKQTTLDAYTHQDAPFEKIVDRINTGRDTSRSPLFQVMFVLQNNTDLPQL
                     HLGDITLHEETAPYRAAKFDLTFDVKESNGELRLTIEYNTDLFLRETAERTGRHFEQLL
                     RAITESPAAAIGTLNGITPGEREELLHHLNDTAADYPKGDTIASLFEAQAARTPGSIAV
                     LFDHRQWTYAELNAKANRLAHYLREQHRIQPNELVAVQLERSEWLVAVLLGILKSGAAY
                     VPIDPAYPQERIDYMLADSRARVVMDEALLQRFHAEEERWSDADPARVNAATDLAYVIY
                     TSGSTGQPKGVMIGHDNATSFLHWCAEEFRASRFDTVFAATSICFDLSVFEIFHTLGAG
                     KQLRMLDNALSIPNHLANAENILLNTVPSVVGNLLREGVDLGRVTVLNMAGEPIPPQYI
                     GALAKWKLEIRNLYGPSEDTTYSTCYRIKSEGRILIGRPIANTQVYLLNRQLQLVPRGA
                     VGEICIGGEGLAKGYLNKPELTAEKFVVNPYKYGDRLYRTGDLGRWLPDGNIEYLGRID
                     HQVKIRGYRIELGEIENALNRHPAINGAVVIARQTANGSELLAYISGEAITTTELRDWL
                     GRTLPAYMIPAYFVVLKELPLTPNGKVDRKRLPASDGLEMAAGATYTAPRNETEERLAN
                     IWAEALGRSRVGIDDNFFEIGGHSLLLLQLTNRINDAFGARLRLIDLMQHLTIGSLSIF
                     IRSAQEPVNPYRITLREGCNSTPAFIIPGMPGISDSYAALAQQLPGSGAVYGLQMKGYQ
                     GEAEPLATIEEMAAHNIALIREVAVAGTISLYAHSYGGTVAYEMLRQLEGSDLTVAQVV
                     FLDSYPWEVQTLKGTRTPPELMRAFLDEAGAYDGAGITGGMNKDNFAHLWKLVERSLSV
                     RYACTERLDRHVTLVIANESTEDRDGSQRSQWSSHFGAATIINTPGNHFSIVKAPDCTA
                     WLSIIDKNYKLNTV"
     aSDomain        complement(2559..3218)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg228_3_Thioesterase.1"
                     /evalue="4.50E-23"
                     /label="ctg228_3_Thioesterase.1"
                     /locus_tag="ctg228_3"
                     /protein_end="997"
                     /protein_start="777"
                     /score="74.6"
                     /tool="antismash"
                     /translation="FIIPGMPGISDSYAALAQQLPGSGAVYGLQMKGYQGEAEPLATIE
                     EMAAHNIALIREVAVAGTISLYAHSYGGTVAYEMLRQLEGSDLTVAQVVFLDSYPWEVQ
                     TLKGTRTPPELMRAFLDEAGAYDGAGITGGMNKDNFAHLWKLVERSLSVRYACTERLDR
                     HVTLVIANESTEDRDGSQRSQWSSHFGAATIINTPGNHFSIVKAPDCTAWLSIIDKNY"
     aSModule        2559..4925
                     /complete
                     /domains="nrpspksdomains_ctg228_3_AMP-binding.1"
                     /domains="nrpspksdomains_ctg228_3_PCP.1"
                     /domains="nrpspksdomains_ctg228_3_Thioesterase.1"
                     /final_module
                     /locus_tags="ctg228_3"
                     /monomer_pairings="ala -> ala"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(2970..3014)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg228_3_0007"
                     /evalue="2.40E-04"
                     /label="NRPS-te1"
                     /locus_tag="ctg228_3"
                     /protein_end="860"
                     /protein_start="845"
                     /score="13.7"
                     /tool="antismash"
                     /translation="HSYGGTVAYEMLRQLE"
     aSDomain        complement(3282..3485)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg228_3_PCP.1"
                     /evalue="1.50E-21"
                     /label="ctg228_3_PCP.1"
                     /locus_tag="ctg228_3"
                     /protein_end="756"
                     /protein_start="688"
                     /score="68.2"
                     /tool="antismash"
                     /translation="EERLANIWAEALGRSRVGIDDNFFEIGGHSLLLLQLTNRINDAFG
                     ARLRLIDLMQHLTIGSLSIFIRSA"
     CDS_motif       complement(3774..3839)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg228_3_0006"
                     /evalue="6.30E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg228_3"
                     /protein_end="592"
                     /protein_start="570"
                     /score="40.5"
                     /tool="antismash"
                     /translation="YLGRIDHQVKIRGYRIELGEIEN"
     aSDomain        complement(3804..4925)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg228_3_AMP-binding.1"
                     /evalue="2.80E-102"
                     /label="ctg228_3_AMP-binding.1"
                     /locus_tag="ctg228_3"
                     /protein_end="582"
                     /protein_start="208"
                     /score="334.1"
                     /specificity="consensus: ala"
                     /tool="antismash"
                     /translation="FEAQAARTPGSIAVLFDHRQWTYAELNAKANRLAHYLREQHRIQP
                     NELVAVQLERSEWLVAVLLGILKSGAAYVPIDPAYPQERIDYMLADSRARVVMDEALLQ
                     RFHAEEERWSDADPARVNAATDLAYVIYTSGSTGQPKGVMIGHDNATSFLHWCAEEFRA
                     SRFDTVFAATSICFDLSVFEIFHTLGAGKQLRMLDNALSIPNHLANAENILLNTVPSVV
                     GNLLREGVDLGRVTVLNMAGEPIPPQYIGALAKWKLEIRNLYGPSEDTTYSTCYRIKSE
                     GRILIGRPIANTQVYLLNRQLQLVPRGAVGEICIGGEGLAKGYLNKPELTAEKFVVNPY
                     KYGDRLYRTGDLGRWLPDGNIEYLGRIDHQVKIRG"
     CDS_motif       complement(3921..4010)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg228_3_0005"
                     /evalue="2.20E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg228_3"
                     /protein_end="543"
                     /protein_start="513"
                     /score="51.9"
                     /tool="antismash"
                     /translation="PRGAVGEICIGGEGLAKGYLNKPELTAEKFV"
     CDS_motif       complement(4485..4544)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg228_3_0004"
                     /evalue="9.00E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg228_3"
                     /protein_end="355"
                     /protein_start="335"
                     /score="33.5"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGQPKGVMIGHD"
     CDS_motif       complement(4695..4736)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg228_3_0003"
                     /evalue="1.00E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg228_3"
                     /protein_end="285"
                     /protein_start="271"
                     /score="18.6"
                     /tool="antismash"
                     /translation="LGILKSGAAYVPIDP"
     CDS_motif       complement(5265..5384)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg228_3_0002"
                     /evalue="1.30E-21"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg228_3"
                     /protein_end="95"
                     /protein_start="55"
                     /score="69.0"
                     /tool="antismash"
                     /translation="KQTTLDAYTHQDAPFEKIVDRINTGRDTSRSPLFQVMFVLQ"
     CDS_motif       complement(5433..5522)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg228_3_0001"
                     /evalue="1.50E-18"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg228_3"
                     /protein_end="39"
                     /protein_start="9"
                     /score="59.0"
                     /tool="antismash"
                     /translation="DICVGSPIANRTHPETEPLIGFFVNMLALRS"
ORIGIN
        1 ggcggacgtt tgagcgtgaa tgaattttga tcatgctact ttgatttttc cgccatcaac
       61 tcggccaact gatcgatggt ctgggcgctc acgaactcga tgcgcggcac gtcgaggttc
      121 agcttttcga gggtgagggt gatgagctct ccgcggtcga tggagttggc gcccagctcg
      181 acgaagctat cgtcgtccga aaatttttcg tcgttcagct cgggcatgat ctcgagcagg
      241 ttttccctga tcaatgaggc gatttcctgt ttcatgtttt tagtaattga ggtgttagtt
      301 gactatggtt tgaaatgttt tttcgaaaag cagggcggct tcttccatca gcaggatgcc
      361 gatagcatcc acgtggcggt tgcgccagct ttcgagctcc gtgcccttca cccattggtt
      421 gaaggatccg agcgccgggc cggtatgcac ctgaaagttc acgcgatcgt cggtatcgcc
      481 ctcgagcgcc agccggttgc tgtagtggaa ataccatttg aatacgaggg ccatcttctg
      541 cttggcattg gcttcggcgg tggtaatggt cgcttcagcg ccgcggttgc gcaggtgcac
      601 tttcgtgtcc tcccacacgg tgctgagcgg ccggcggaaa taattgtcct cgatctgtcg
      661 gatcaccttg cccggtatgt cctcgagcga atcgtactgg ttatagaggg tgaacagctt
      721 gttggcccgc gcgggaaaga gcacgctttt tttcagtacc tgcactttcg agccgatctc
      781 gaacatgtca cccgccggcg cgtaatcggt gtcctgtacg tttatctcct gcaatatatc
      841 tttcactacg ttgcttgcgc ccgcctccac ggtgcactgg ttgatggagc cggtgagcac
      901 gaagtccgca cccatcatga aggtgcaggc cacggcttgc ggcgtgccga tgccccccgc
      961 aagtcctaca tggatcggcc ggtcgtaacc ctgctctttg gcgatgcgta tgcgcagctg
     1021 ctggatggct ggcagcagca ccagcgccac gccccggtcg gtatgaccgc ccgaatcggc
     1081 ctccacgcag atatcgtgac tcatgggtgt ttgttgcgaa agcgcggcct gctctgcggt
     1141 gatgagtcct tcctccaaca actggttgac gatcttcatc ggcggcggtc gcaggaaggc
     1201 ctcggccact tcgggtcgcg ataccttggc gatcacctgg tgcttgcaaa ggatagagcc
     1261 gtccgctcct ttgctcaatc cttttacgcg atagtacacg agcgccggcg ttatttggat
     1321 ataggccgag gcctccaccc gggtgatgcc cttgcgcagg tagagctcca ctgttttcat
     1381 ttcgcgctgc gggttggcga actggtgaag gaggttgaag ccatacggct cgccttgggt
     1441 aagggctgcc tgtaccgaat ctatgctcgc ttcgatctcg gcaaaagaaa gaccgcccgt
     1501 accaaaaaag ccgagcaggc cggccctgcc catgcggatc accatttctt tcgaagcgat
     1561 gcctttatac atggagccgg ccacataggc ataacgtatg ccgtaggcgg atttgaagct
     1621 gctgctgccg atgcgccctg cgcgtgtggc cggagctggc tgctgcggcg catattcagc
     1681 cgcctccgcc ttttcctcgt cgaaaactgg cgtgctatcg ttgcggatct ccgccaccat
     1741 cttggaaagt agggagccgc cgatctcgtc gaaatcggaa acgcccttgc ccatgaggta
     1801 gcgaacggtg tcggtccact gcacggggct ggcgatctgc cggctcagaa ggtccgctac
     1861 gtcattaccg tagggccgag cggttacgtt cgatataacg gggatgccta gccgagaaaa
     1921 ggagaaggag cggagaaagg cggcaaattc ttcggcggcg gcttgcatgt agcgcgagtg
     1981 gaagggcgcg ctcacgttga gcggcaccac gcgaatgcct tgggcatcga gctccttcac
     2041 cagccggatg atgccgtcct gcgtgccggc caccaccgtt tgcgtgggcg tgttgtaatt
     2101 ggctacgtcg atatccgcat agccgccttc gtcaagcttc cggcgaacgg ccgttgcgct
     2161 caggcccagc acagcggcca tggccccgcc cgaggcggcg ctcatcagcg ctcctctttt
     2221 ttgaacaagg cgaaggcccg tctcgaaatc aaaggcgccg gcggccagca gggcattgta
     2281 ctcgccgagg ctgtggcctg cgaggtaggc ggggcgcggc tcctggcgac tgtaccaggc
     2341 cagggcgttc accacgtaga gcgcgggctg cgtgtattgc gtcttgccca gctggcgggc
     2401 gggatcgctc acgcacagct cctcgatgtc gtagcccagc agcgccgatg cccgccccgt
     2461 ttcggcgggg tagagcttga agaggtcttt gcccatgccc ttgtattgag atccctggcc
     2521 cgggaacacg actactttca tacggtattt aatttataat ttttatcaat aatagacagc
     2581 caggccgtgc agtccggcgc tttcacgatc gagaagtgat tgcccggggt gttgatgatg
     2641 gtcgcggcgc cgaagtgact gctccactgg ctgcgctgcg atccgtccct gtcttccgtg
     2701 ctttcgtttg cgatcaccag cgttacgtgg cggtccagcc gttcggtgca ggcatagcgc
     2761 acggagagcg agcgctccac cagtttccag aggtgggcga aattatcctt gttcataccg
     2821 cccgtgatgc ctgcgccgtc gtaagcgccg gcttcgtcaa ggaaggcgcg catgagctcc
     2881 gggggcgtgc gcgtgccctt gagcgtctgc acttcccagg ggtagctgtc caggaatacc
     2941 acttgcgcta cggtcaggtc agagccttcc agctggcgca gcatctcgta ggcaacggtg
     3001 ccgccgtagc tgtgggcata gaggctgatg gtgccggcaa cggccacctc gcggatgagg
     3061 gcgatgttgt gcgccgccat ttcttcgatc gtggccaggg gctcggcttc accctgatag
     3121 cccttcatct gcaagccgta aacggcgccg ctgccgggca gctgctgcgc cagcgccgca
     3181 tagctgtcgc tgatgccggg catgccggga atgatgaagg ccggcgttga attacagcct
     3241 tcgcgaagcg tgatgcggta gggattgacc ggctcttgcg cggaacgtat aaatatggat
     3301 aggctgccga tggtaagatg ctgcatcagg tcgatgaggc gaagccgggc gccgaaggcg
     3361 tcattgatcc ggttggtgag ctgaagcaga agcagggagt ggccgccgat ctcaaagaaa
     3421 ttatcgtcta tccctacccg tgagcgaccc agggcctcgg cccagatatt cgcaagtcgt
     3481 tcttcggtct cgttgcgtgg cgctgtgtaa gtcgcgccgg cggccatttc cagcccgtcg
     3541 gacgcgggca ggcgcttgcg gtcgaccttg ccgttgggcg tgagcggcag ctctttcagc
     3601 accacgaaat aagccggtat catgtaggcg ggcagcgtgc ggcccagcca gtccctcaac
     3661 tcggtcgtcg ttatcgcttc gccggagatg taggccagca gctcgctgcc gttggctgtt
     3721 tgccgggcga tcacgaccgc tccgttgatg gccggatgac ggttcagggc attctcgatc
     3781 tcacccagct cgatgcggta gccgcggatc tttacctggt gatcgatgcg gccgaggtat
     3841 tcgatattgc cgtcgggcag ccagcggccc aggtcgccgg tgcggtacag gcggtcaccg
     3901 tatttatacg ggttgactac aaatttttcg gccgtcagct ccggcttgtt caggtagcct
     3961 tttgccagtc cttcgccgcc aatgcagatc tcgccaacgg cgccgcgggg cacgagttgc
     4021 agctgccggt tgagcaggta aacctgcgtg ttggcgatgg gccggccgat gaggatgcgg
     4081 ccctcacttt ttatgcggta gcaggtgctg taggtcgtat cctccgaagg gccgtagagg
     4141 tttctgatct cgagcttcca ctttgcaagc gccccgatgt attggggcgg gatcggttcg
     4201 ccggccatgt tcagcaccgt tacgcggccc aggtccacgc cttcgcggag caggttgccc
     4261 accacgctcg gcacggtgtt cagtaaaata ttttctgcat tcgcaagatg gttgggaatg
     4321 gacagcgcgt tgtccagcat tcgcagctgc ttgcccgcgc cgagggtatg gaagatctcg
     4381 aacacggaga ggtcgaagca gatggaagtg gcggcaaaga cggtatcgaa gcgcgaggcg
     4441 cggaactctt cggcgcacca atgcaggaag ctggtggcgt tgtcatggcc gatcatcacg
     4501 cccttgggct ggcccgtgga gccggaagtg tagatcacgt aagccaggtc ggtggcggca
     4561 ttcacacgtg cgggatccgc atcgctccat cgttcttctt cggcgtggaa gcgttgcagc
     4621 agggcctcgt ccattacaac gcgggcgcgg ctgtcggcca gcatatagtc gatgcgctcc
     4681 tgcgggtagg cggggtcgat gggtacgtag gccgcacccg atttgagaat ccccagcagc
     4741 acggccacca gccactcgct gcgttccaac tgcacggcca ccagctcgtt gggctgaatg
     4801 cggtgctgct cgcggaggta gtgcgccagc cggttggcct ttgcgttcag ttccgcgtag
     4861 gtccattgac ggtggtcgaa aagaacggcg atactgccgg gcgtacgggc cgcttgcgct
     4921 tcgaacaggg aggcgatggt gtctcctttg ggatagtccg cggccgtatc attcaggtgg
     4981 tgcagcagct cttcgcgctc gccgggcgtg atgccgttga gcgtgccgat ggccgctgcc
     5041 ggactttccg taatcgcgcg gagaagctgc tcgaaatgac ggccggtgcg ttccgccgtt
     5101 tcgcggagaa agaggtcggt attgtactcg atcgtcaggc gcagctcgcc gttgctttcc
     5161 ttaacgtcga aggtgaggtc gaacttggcg gcgcgatagg gtgcggtctc ttcgtgcagg
     5221 gttatgtcgc ccaggtgcag ctgcggaagg tcggtattgt tttgcagaac gaacatcacc
     5281 tggaacagcg ggctgcggct cgtatcgcga cccgtattta tacggtcgac tatcttttcg
     5341 aagggcgcgt cctgatgggt gtaagcatcg agggttgttt gcttcacctg ggccagcagc
     5401 gcggtaaagc tgtcgtcgtt ccttacctcg ctgcgcaagg ccagcatgtt cacgaagaag
     5461 ccgatcagcg gctcggtttc gggatgcgtg cggttggcga tgggcgagcc cacgcaaata
     5521 tcttcctgcc cggaatactg atgcagcaat
//
