LOCUS       c00415_3300023..       11312 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300023267.a:Ga0247771_1000586.
ACCESSION   c00415_3300023..
VERSION     c00415_3300023..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 15:23:16
            Original ID  :: 3300023267.a:Ga0247771_1000586
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11312
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11312
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[8460:11310](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(8461..11310)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..11312
                     /SMILES="NCC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11312
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             complement(3..890)
                     /locus_tag="ctg415_1"
                     /transl_table=11
                     /translation="MTDTKTSSPHDPSLYNEDLAIVPPRKRTWTTWNYVALWVSMSLCI
                     PTYMLASSLIEGGMNWWQAIVTIFLGNMVVLVPMILNGRAGARYGIPFPVLARSSFGVR
                     GANIPALLRAIVACGWFGIQTWIGGYALYQMVRLWWPSIDALPQLFPASFELASGPALC
                     FFVFWLINMLVVYLGVDSIKKLLVFKAFFLPLAALALVFWAVSASHGLGPILKTPSKFT
                     DSASFWKYFFPALTGMVGFWATLSLNIPDFTRYARSQRAQVRGQAIGLPASMTLFAFIG
                     VVVTSATTIIYGTTI"
     CDS             complement(907..2268)
                     /NRPS_PKS="Domain: Aminotran_3 (36-374). E-value: 5.1e-89.
                     Score: 290.3. Matches aSDomain:
                     nrpspksdomains_ctg415_2_Aminotran_3.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013:aminotransferase class-III (Score: 377.3;
                     E-value: 1.5e-114)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg415_2"
                     /transl_table=11
                     /translation="MLDTVAATFLSEEIIQDNFDYTLFSWSKQKGHRPIAVERAEGVYL
                     YDYSGKRYIDFSSGLMNVNIGHGHPRITEAVVRQMQRVSYVTPSCVTKARGDLGKKLAQ
                     ICPGDLNKAFFTVCGASSIENAIKLARLYTGRHKILARYQSYHGATGGALSASGDPRRQ
                     PVDAQQAPNFVHFDLPYLYRWDYGEANLLKESVHQLERLIEYEGTASIAAIILEGESGT
                     SGCLKYPIGYMKAVRALCDRYGILLISDEVMSGFGRTGQWFGFQNHDIVPDMIAMAKGL
                     TCGYLPFGCLMVSDRIAGKYDDAVLPLGLTYSAHPVCCAAALETLQVYEDEDLIDRAAA
                     TGRYIDSQVARLREQHPSIGDWRNTGLLGCLELIKDRETKEPLAPFNAKPQEMGVMNEV
                     AGRIRELGMYTFVRWNYVFIAPPLTITRDQVDEGLAIIGEALTIADKAVTGRAS"
     aSDomain        complement(1147..2160)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg415_2_Aminotran_3.1"
                     /evalue="5.10E-89"
                     /label="ctg415_2_Aminotran_3.1"
                     /locus_tag="ctg415_2"
                     /protein_end="374"
                     /protein_start="36"
                     /score="290.3"
                     /tool="antismash"
                     /translation="VERAEGVYLYDYSGKRYIDFSSGLMNVNIGHGHPRITEAVVRQMQ
                     RVSYVTPSCVTKARGDLGKKLAQICPGDLNKAFFTVCGASSIENAIKLARLYTGRHKIL
                     ARYQSYHGATGGALSASGDPRRQPVDAQQAPNFVHFDLPYLYRWDYGEANLLKESVHQL
                     ERLIEYEGTASIAAIILEGESGTSGCLKYPIGYMKAVRALCDRYGILLISDEVMSGFGR
                     TGQWFGFQNHDIVPDMIAMAKGLTCGYLPFGCLMVSDRIAGKYDDAVLPLGLTYSAHPV
                     CCAAALETLQVYEDEDLIDRAAATGRYIDSQVARLREQHPSIGDWRNTGLLGCLELIK"
     CDS             complement(2300..3757)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 431.1; E-value:
                     6.6e-131)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg415_3"
                     /transl_table=11
                     /translation="MRYPAVQNFINGQFVSAASDRSLDVISPLDGERLSTVPLSSAADL
                     DRAVATAMTAFAGWSRTPIKERVQVFFKYKYLLEKNMQELAALCSEENGKTIGESIAEI
                     EKCIELTEFACSLPQLVTGEVLEVSKGVECRTEHVPLGVVASIVPFNFPSMVPNWTIPN
                     ALALGNCMILKPSEKVPLSAGRLAQLLQEAGLPDGVLNIVHGDVGIVEAICDHPHIEAV
                     SFVGSTKVARIVYQRATQSYKRCLALGGAKNHLMVMPDAIPGMTAQNVAASMSGCAGQR
                     CMAASAMVAVGAVDHIIQGIVAEAKKIVPGQNLGAVISREAKERIEKYITEAEAEGATI
                     LVDGRNAVVDGKEGGSYVGPTVIDHVTPGMAVAREEIFGPVISIMRAGTVDEALAIENA
                     NPYGNAASVFTQNGGVARYIIDRASAGMVGVNVGVPVPREPFSFGGWNESKFGVGDITG
                     KSSIEFWTKLKKSTVKWNPEAGVNWMS"
     CDS             3879..4334
                     /locus_tag="ctg415_4"
                     /transl_table=11
                     /translation="MEQTIQNFYPVKVWLATNVSGTFFLLLGFIFSAGTGMRDIADAMP
                     IVLYIFFFGLLFSVPALGLFWVLFLWIKRLDMGISGKKAILIGGGMVMILLTFFIITSD
                     LFSPTNSTWLVFPGAYSAALAFSVWLIHLYKTPRLETDFAPEPGETI"
     CDS             4443..5477
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111:GCN5-related N-acetyltransferase (Score: 128.9;
                     E-value: 3.1e-39)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg415_5"
                     /transl_table=11
                     /translation="MERTTRTYYPLRILLMTHLAGPLIAVPVMVLREGGNFEDFLADEI
                     RGVIIWAIGTGFSMPSFGIFWLLFLGIKDLHIGTWAKKLILLIGGLPLVWLTFYLLNNA
                     FYKTENWMTDYITLIYAATFAFAVLYTGLYRKPRPEPKPQAEPAEALQDTTSIYTYREK
                     VEKEFVIETERLYLRHIQLSDEDGIFELDSSPAVHAYLGKRPITTRAQAREAIEYIRRQ
                     YLENGIGRWAVIDKETSEFIGWAGLKFIGEEINGLSGFYDVGYRLIERYWGRGLATEAT
                     IAALNYAFKTMKLREVYGMCDVRNKASRRVLEKAGLTWLGTFILDGDEHDWLRIRRKEF
                     SARS"
     CDS             complement(5651..8320)
                     /locus_tag="ctg415_6"
                     /transl_table=11
                     /translation="MNRLRFASGALALLAFSAGAQDRPIYEAGAYQLYRDSIVQGPYRA
                     DALSDGALRSNYRSAANEYKSVNIGFKFSINGKDNEMKPGIDHHFTYTATDGSAETPII
                     RFGTQLNQKPAGGYLPAGTRLTFRLDMREVLQAFDTKGYYTTYNGDKIYKTDFKGVYVA
                     GNTTPLIWDFDNLVNHQQLQLHDRDGDGIYEATLVLNKSDDAPATAPEWRQRRDLSAFP
                     SYTSPFTITNTLYNLAIEEMINAVEPDSTFRTGKEWAGVWTRDISYSIILAMAHLQPEV
                     AKKSLLRKVSAKKKIIQDTGTGGAWPASTDRAIWAVAAWELYKVTGDKDWLQQAYVIIK
                     NSIDDDSHVAYNPATGLVKGESSFLDWREQTYPKWMQPVDIAESECLGTNAVHYQANNV
                     LARMAAALNHPAEAARYGAVAERIKKAINNYLWLPQQQYYGQYIYGRNSRLLSPRAEAL
                     GEALCVIFGIAPEDRARNIVAHVPQTAYGISCIYPQIPDIPPYHNNAVWPFVQTYWLWA
                     AAKAGNEKAVTESMAAIYRPAALFATNKENFVADNGDFAGTQINSSNMLWSLSGNISIV
                     HKVLFGVRFNEDGLSFEPFVPRVFAGKRSLNNFRYRRAVLDIDMNGWGNRIREFWLDGK
                     KQAQATLAAGLQGHHAIRIVLANNATGGTINRVANHTTLPAPDVSYDGRTLSWTKMPAT
                     KAFQVWKNGRLIATTNAVQWPASDNSYAEYQVIAMDAEGYPSFASEPVTTGTSRAIRYE
                     LEDIKGKDRHEGQGYSGTGFTHISVTKNTTVEMPVKVEESGLYAIDFRYANGNGPTNTE
                     NKCALRTLEVDGVTVGTSLFPQRGKDEWSNWGFSNAVRVKLSRGNHTLRLIYKDWNENM
                     NGAINEALLDYVRLLKVE"
     CDS             complement(8461..11310)
                     /NRPS_PKS="Domain: AMP-binding (0-334). E-value: 2.2e-82.
                     Score: 268.5. Matches aSDomain:
                     nrpspksdomains_ctg415_7_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (440-510). E-value: 4.6e-21. Score:
                     66.6. Matches aSDomain: nrpspksdomains_ctg415_7_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (526-806). E-value:
                     1.3e-59. Score: 193.4. Matches aSDomain:
                     nrpspksdomains_ctg415_7_Condensation_LCL.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     273.1; E-value: 6.3e-83)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg415_7"
                     /sec_met_domain="Condensation (E-value: 3.4e-58, bitscore:
                     185.9, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3.7e-95, bitscore:
                     307.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.9e-14, bitscore:
                     41.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRSARLVAVLLGVLKSGRAFIPLDPAFPADRLRYIVGHSRAACI
                     AGTDEFKNLFEGTPFISIDAMNDSNSELPTVSSSGDAYIIYTSGSTGQPKGVVVGHRSL
                     LNFLLSMQRRPGLAEGDLFFSVTTQSFDISMLEFFGPLVSGGSIYIAGREVVLNPPVLV
                     ARLQALRPAIIQATPSLYQLLFDAGWPGDERLKVLCGGDLLGSALAAQLLRSCAELWNM
                     YGPTETTIWSSLRKITDPEQSSNIGRPIANTQLYILDDCGQLLPVGMAGELHIGGDGLA
                     KGYHRAPELTAERFIDDPFHEGKKIYRTGDLARWTADGTVDFLGRNDHQVKIRGYRIEL
                     GEIESRIDALPSVHASVVVAHKGNGDVVLVAYVVPGEKDIDTVFIRSALQEVLPAYMVP
                     QVIVPLDSFPLTPNKKIDRKQLASRPIEAVASPEAAPATALEEQLCGLFGEALGHSIRI
                     NTGDDFFALGGHSLNAMKLVNLVENRLQYKLALRTVFDFPTVQALALHLGRQQAVAQTG
                     ITVSAPRPWYPLTPAQYAIWLAAQGNEERSSAYNVFNLYEISGALDIDRLQNAFLRLIE
                     KYEVLRTRFAEREGGPAQLFVSATDFTIDRIDPADDEWAAMEDYVNRPFDLESGLLLRA
                     GLFVKEGRSFLAFATHHIIMDGWSVEILMRAVVDQYRGEGVDEALPFQFRDYIDWLETA
                     AAAREETNRTFWTGYLEGHRWKTAPTASLEPAAGEQHFEWTGDFFSSLRGAVRRQGTTL
                     HNFLAAAFFILWHRQEGDEDMCIGTVNSGRTLEGLHEQLGMFVKTLPLRVRLDPAASFT
                     QLLASVQAGLLGIDAHQDLPADIYSRLRLDVLFVLQPLSFNYDAIELAQGLRLSALPIA
                     QRFSRLPLLVNFREDGDALRCTLTYDKKRWTAEAIDVLMMKYEKVLVQLIENAHGPIED
                     LDSSLVLPETPALDFEFDF"
     aSDomain        complement(8893..9732)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg415_7_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="1.30E-59"
                     /label="ctg415_7_Condensation_LCL.1"
                     /locus_tag="ctg415_7"
                     /protein_end="806"
                     /protein_start="526"
                     /score="193.4"
                     /tool="antismash"
                     /translation="YPLTPAQYAIWLAAQGNEERSSAYNVFNLYEISGALDIDRLQNAF
                     LRLIEKYEVLRTRFAEREGGPAQLFVSATDFTIDRIDPADDEWAAMEDYVNRPFDLESG
                     LLLRAGLFVKEGRSFLAFATHHIIMDGWSVEILMRAVVDQYRGEGVDEALPFQFRDYID
                     WLETAAAAREETNRTFWTGYLEGHRWKTAPTASLEPAAGEQHFEWTGDFFSSLRGAVRR
                     QGTTLHNFLAAAFFILWHRQEGDEDMCIGTVNSGRTLEGLHEQLGMFVKTLPLRVRLDP
                     "
     aSModule        8893..9732
                     /domains="nrpspksdomains_ctg415_7_Condensation_LCL.1"
                     /incomplete
                     /locus_tags="ctg415_7"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(8905..8994)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg415_7_0007"
                     /evalue="1.50E-08"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg415_7"
                     /protein_end="802"
                     /protein_start="772"
                     /score="27.1"
                     /tool="antismash"
                     /translation="DMCIGTVNSGRTLEGLHEQLGMFVKTLPLRV"
     CDS_motif       complement(9298..9360)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg415_7_0006"
                     /evalue="1.80E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg415_7"
                     /protein_end="671"
                     /protein_start="650"
                     /score="30.1"
                     /tool="antismash"
                     /translation="HHIIMDGWSVEILMRAVVDQYR"
     CDS_motif       complement(9553..9669)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg415_7_0005"
                     /evalue="6.30E-13"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg415_7"
                     /protein_end="586"
                     /protein_start="547"
                     /score="41.1"
                     /tool="antismash"
                     /translation="SAYNVFNLYEISGALDIDRLQNAFLRLIEKYEVLRTRFAE"
     CDS_motif       complement(9694..9732)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg415_7_0004"
                     /evalue="4.40E-03"
                     /label="C1_starter_004-017"
                     /locus_tag="ctg415_7"
                     /protein_end="539"
                     /protein_start="526"
                     /score="10.0"
                     /tool="antismash"
                     /translation="YPLTPAQYAIWLAA"
     aSDomain        complement(9781..9990)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg415_7_PCP.1"
                     /evalue="4.60E-21"
                     /label="ctg415_7_PCP.1"
                     /locus_tag="ctg415_7"
                     /protein_end="510"
                     /protein_start="440"
                     /score="66.6"
                     /tool="antismash"
                     /translation="EEQLCGLFGEALGHSIRINTGDDFFALGGHSLNAMKLVNLVENRL
                     QYKLALRTVFDFPTVQALALHLGRQQ"
     aSModule        9781..11310
                     /complete
                     /domains="nrpspksdomains_ctg415_7_AMP-binding.1"
                     /domains="nrpspksdomains_ctg415_7_PCP.1"
                     /locus_tags="ctg415_7"
                     /monomer_pairings="gly -> gly"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(10279..10344)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg415_7_0003"
                     /evalue="6.40E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg415_7"
                     /protein_end="344"
                     /protein_start="322"
                     /score="40.5"
                     /tool="antismash"
                     /translation="FLGRNDHQVKIRGYRIELGEIES"
     aSDomain        complement(10309..11310)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg415_7_AMP-binding.1"
                     /evalue="2.20E-82"
                     /label="ctg415_7_AMP-binding.1"
                     /locus_tag="ctg415_7"
                     /protein_end="334"
                     /protein_start="0"
                     /score="268.5"
                     /specificity="consensus: gly"
                     /tool="antismash"
                     /translation="MPRSARLVAVLLGVLKSGRAFIPLDPAFPADRLRYIVGHSRAACI
                     AGTDEFKNLFEGTPFISIDAMNDSNSELPTVSSSGDAYIIYTSGSTGQPKGVVVGHRSL
                     LNFLLSMQRRPGLAEGDLFFSVTTQSFDISMLEFFGPLVSGGSIYIAGREVVLNPPVLV
                     ARLQALRPAIIQATPSLYQLLFDAGWPGDERLKVLCGGDLLGSALAAQLLRSCAELWNM
                     YGPTETTIWSSLRKITDPEQSSNIGRPIANTQLYILDDCGQLLPVGMAGELHIGGDGLA
                     KGYHRAPELTAERFIDDPFHEGKKIYRTGDLARWTADGTVDFLGRNDHQVKIRG"
     CDS_motif       complement(10426..10515)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg415_7_0002"
                     /evalue="6.30E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg415_7"
                     /protein_end="295"
                     /protein_start="265"
                     /score="50.4"
                     /tool="antismash"
                     /translation="PVGMAGELHIGGDGLAKGYHRAPELTAERFI"
     CDS_motif       complement(11008..11067)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg415_7_0001"
                     /evalue="2.60E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg415_7"
                     /protein_end="101"
                     /protein_start="81"
                     /score="32.1"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGQPKGVVVGHR"
ORIGIN
        1 caaatggtcg ttccataaat tatcgtcgtt gccgatgtga ccaccacgcc gataaaagca
       61 aaaagggtca tcgatgcagg cagaccgatg gcctggccgc gaacctgcgc ccgctggctg
      121 cgggcatagc gggtgaagtc gggaatgttg agcgagagcg tagcccagaa accgaccatg
      181 ccggtgaggg cggggaaaaa atatttccag aaggacgcgc tgtccgtaaa cttcgacggc
      241 gtcttcagga tcgggcccag cccatgcgag gccgacacgg cccagaacac aagggccagc
      301 gccgccagcg gcaggaagaa ggctttgaac accagcagct tttttatgct gtcgacaccc
      361 agataaacca cgagcatatt gatcagccag aatacgaaaa agcaaagcgc cggtcctgaa
      421 gccagctcga atgaagcggg aaatagttgc ggcaacgcat cgatggacgg ccaccaaagg
      481 cgcaccatct gataaagcgc atagccgccg atccaggtct gaatgccgaa ccagccgcag
      541 gccacgatgg cgcgcagcag ggcgggaata ttggcgccgc gcacgccgaa gctcgagcgc
      601 gccagcacgg gaaaaggtat gccgtacctg gcgccggcgc ggccgttgag gatcatcggc
      661 accagcacta ccatgttgcc gagaaagatc gtgacgatgg cctgccacca gttcatgccg
      721 ccttctatca gcgagctggc aagcatataa gtgggaatgc aaaggctcat gctcacccag
      781 agggctacgt agttccacgt ggtccaggtg cgcttgcgcg gcggcacgat ggccaggtct
      841 tcgttgtaga gcgatggatc gtgcgggctg ctcgttttgg tatcggtcat gccttatact
      901 tatggtttat gatgcgcggc cggtcacggc cttgtcggcg atggtgaggg cttcgccgat
      961 gatggccagt ccttcatcca cctggtcgcg ggtaatggtg agcggcggtg cgatgaacac
     1021 atagttccag cgtacgaagg tgtacatgcc cagctcgcgg atgcggccgg ccacttcgtt
     1081 catcacgccc atctcctgcg gctttgcatt gaagggcgcc agcggttctt tcgtctcgcg
     1141 gtcctttata agctcgaggc agccgagcag tccggtgttg cgccagtcgc cgatgctggg
     1201 atgctgctcg cgcaggcggg ccacctggct gtcgatatag cggcctgtgg cggcggcgcg
     1261 gtcgatgagg tcttcgtctt cgtacacctg cagggtttcg agggcggcgg cgcagcacac
     1321 ggggtgggcc gagtaagtaa gtccgagggg cagcaccgca tcatcgtatt taccggcgat
     1381 gcgatcgctc accatcaggc agccgaaggg caggtagccg caggtaagcc ccttggccat
     1441 ggcgatcatg tcgggcacga tgtcgtggtt ctggaagccg aaccactggc cggtgcgacc
     1501 gaagccgctc atcacctcgt cgctgatgag gaggatgccg tagcggtcgc agagcgcgcg
     1561 aacggccttc atataaccta tgggatattt gaggcagccc gaagtgcccg actcgccctc
     1621 gaggatgatg gcggcgatgc tggcggtgcc ttcatattcg atgagacgtt cgagctggtg
     1681 caccgattct ttcaggaggt tggcctcgcc atagtcccac cggtataaat acggtaggtc
     1741 gaagtgtacg aagttgggcg cctgctgggc atccacgggc tggcggcgcg ggtcgccgct
     1801 ggccgagagg gcgccgccgg tagcgccgtg gtacgactgg tagcgggcca gtatcttgtg
     1861 ccgcccggtg tagaggcggg cgagcttgat ggcgttctcg atggagctgg cgccgcaaac
     1921 ggtgaagaag gctttgttca gatcgccggg gcagatctgc gcaagctttt tcccgaggtc
     1981 gccgcgggcc ttggttacgc agctgggcgt tacatagctc acccgctgca tctggcgcac
     2041 gacggcctcg gtgatgcgcg ggtgtccatg gccgatgttc acgttcatca gtcccgaaga
     2101 gaaatcgatg tagcgcttgc cgctgtagtc gtaaaggtaa acgccctcgg cgcgctccac
     2161 ggctatgggg cgatgaccct tctgcttgct ccaggaaaaa agggtgtagt cgaaattgtc
     2221 ctggatgatc tcttcggaca ggaacgtggc ggccacggta tcgagcatat aattattttt
     2281 tatataatat taataaatat caggacatcc agttgacgcc cgcctcgggg ttccacttga
     2341 cggttgattt tttgagcttg gtccagaact cgatggagct cttgccggtg atgtcgccca
     2401 cgccgaactt gctttcgttc cagccgccga aagaaaaggg ctcgcgcggt acgggcacgc
     2461 ccacgttcac gcccaccatg ccggcgctgg cccggtcgat gatgtagcgg gctacgccgc
     2521 cgttctgcgt aaataccgaa gcggcattgc cgtatgggtt ggcgttctcg atggccaggg
     2581 cttcgtccac ggtcccggcc cgcatgatgc tgatgacggg accgaagatc tcctcacgcg
     2641 ccacggccat gccgggcgtt acatggtcga tgacggtggg gcctacatag ctgccgcctt
     2701 ccttgccatc gacgacggcg ttgcgtccat cgacgaggat ggtagcgcct tcggcctcgg
     2761 cctccgtaat atatttttcg atgcgctctt tggcttcgcg gctgatgacg gcgccgaggt
     2821 tctgacccgg aacgatcttt ttcgcttcgg caacgatgcc ctgtatgata tgatccaccg
     2881 cacctacggc caccatggcc gatgccgcca tgcaacgctg acctgcgcag ccgctcatgg
     2941 aggccgccac gttctgggcc gtcatgccgg ggatggcatc gggcatgacc atcaggtggt
     3001 tcttggcgcc gccgagggcg agacagcgct tgtagctctg tgttgcgcgc tggtaaacga
     3061 tcctggccac cttggtcgag ccgacaaaag acacggcttc gatatgggga tgatcgcaga
     3121 tggcttccac gatgcccacg tcgccgtgaa cgatattgag cacgccgtcg ggcagtccgg
     3181 cctcctgcaa aagctgcgcg aggcggccgg cgctgagggg tactttttca ctcggcttca
     3241 ggatcatgca attgccgagg gcgagtgcat tggggatggt ccagttgggc accatgctcg
     3301 gaaaattgaa gggcacgatg gaagcgacga cacccagcgg cacgtgctcg gtgcggcatt
     3361 ccacgccctt gctcacttca agcacctcgc cggtaacgag ctggggcagg gagcaggcga
     3421 actcggtgag ctcgatacat ttttcgatct cggcgatgga ctcgccgatg gtcttgccgt
     3481 tctcctcgga gcagagggcg gcaagctcct gcatattttt ttcgaggagg tatttgtatt
     3541 tgaaaaagac ctgtacgcgt tccttgatgg gtgtgcgcga ccagccggca aaggccgtca
     3601 tggcggtggc aacggcgcga tcaaggtcgg cggcggacga gaggggcacg gtggagagtc
     3661 gttcgccgtc gaggggcgag atcacgtcga gcgacctgtc ggaggctgcg gacacgaact
     3721 ggccattgat aaagttctgt actgccgggt agcgcatgga aataatttag tctggacaat
     3781 ttactctttt tgaatgagaa ccggaagagc gaataacacc cgtccgccgc gcaaccgccg
     3841 ggctgtttta tccgtaaatt gccggtaaag caggctcgat ggaacaaacg atacagaatt
     3901 tttacccggt gaaggtctgg ctggcaacga acgtctcagg cacctttttt cttttgctgg
     3961 gtttcatatt cagcgccggc acgggcatga gggatattgc agacgcgatg ccgatcgttt
     4021 tgtacatatt ctttttcggc ctgctgtttt cggtgccggc gctgggactt ttttgggtat
     4081 tgttcctatg gatcaagcgc cttgacatgg gaatatcagg aaaaaaagcg atcctcatcg
     4141 gcggcggcat ggtgatgatc ctgctcacat tttttatcat cacgtccgac ctgttctctc
     4201 ctaccaattc gacatggctg gtttttcccg gggcttattc ggcggcactg gcattcagcg
     4261 tatggctcat ccacctgtat aaaacaccac ggcttgaaac ggacttcgca cccgaaccgg
     4321 gggaaacgat ttaagcaaga gcgggagctg cggcgcggtg gaattgccat tgacaaattt
     4381 ctgatcgtcc gaataaatat tttaatttaa ataattattt ttttaaatct aaccgggttg
     4441 tcatggaacg aaccacaaga acctattacc cgctccgcat cttgctgatg acgcatcttg
     4501 cagggccgct catagcggtg ccggtcatgg tcttgcgcga aggcggaaac tttgaggatt
     4561 ttctcgcgga cgaaatccgg ggcgtgatca tctgggccat cggaacaggg ttctcaatgc
     4621 catcgttcgg gatcttctgg ctgctgttcc tgggcattaa ggacctgcat atcgggacat
     4681 gggcaaaaaa gctgatcctc cttatcggcg gcctgccgct cgtctggctc actttttatc
     4741 tcctcaataa tgccttttac aaaacggaga actggatgac ggactacatc accctcattt
     4801 atgcggccac cttcgccttt gccgtattat acacagggct gtacagaaaa ccccgccccg
     4861 agcccaaacc tcaagccgaa ccggccgaag cgctacagga cacaaccagt atttatacgt
     4921 atcgcgagaa agtggaaaag gaatttgtca tagaaaccga acgcctctac ctgcgccata
     4981 tccagctctc cgacgaggac ggcatctttg agctggacag cagtcccgcc gtccacgcct
     5041 acctcggcaa gcggcccatc accacgcggg cgcaggcgcg ggaagccatc gaatacatcc
     5101 gccggcagta cctcgaaaac ggcatcggcc gctgggccgt gatcgacaag gaaacctcgg
     5161 aatttatcgg ctgggccggt cttaaattta tcggcgaaga gatcaacggc ctgtccggtt
     5221 tttacgatgt cggctaccgc ctcatcgaac gctactgggg ccgcgggctg gccacagaag
     5281 ccacgatcgc agcgctgaac tatgccttca agacgatgaa gctgcgcgaa gtctacggca
     5341 tgtgcgacgt acgcaacaaa gcctcgcgcc gcgttctcga aaaagccggc ctcacgtggc
     5401 tcggcacctt catcctcgac ggcgacgagc acgactggct gcgcattcga agaaaagagt
     5461 tttcagctcg cagttagcag taggcagttg gtgtcctaaa gaagtaatcg ctttataata
     5521 ccggcctcat tttgttcagt ttagttgcat aaaaagggtc cgtataaata cggaccctaa
     5581 ctctttagtg aaccaactgc ctactgccaa ctgcttactg ctaactgccg tagcttcagc
     5641 gaaggcgagg ctactctact ttcaaaagcc gtacatagtc cagcaaggct tcgttgatgg
     5701 cgccgttcat gttttcgttc cagtccttgt atataaggcg cagcgtgtgg ttgccccgcg
     5761 acagcttcac gcgcaccgca ttgctgaagc cccagttcga ccattcgtcc ttgccgcgct
     5821 gcggaaagag gctcgtgccc acggtcacgc catccacctc gagcgtgcgg agggcgcact
     5881 tgttctcggt attggtcgga ccgttgccgt tggcatagcg gaagtcgatc gcatagagac
     5941 cgctctcctc caccttcacc ggcatttcta cggtcgtatt ttttgtaacg ctgatatgcg
     6001 tgaagccggt ccccgagtaa ccctgacctt cgtgccggtc cttgcccttg atatcctcca
     6061 gctcatatct tatcgcgcgg ctcgtgcccg tagttaccgg ctcgctggcg aaggagggat
     6121 aaccctcggc atccatagcg atcacctggt actcggcata ggaattatcg gaggcgggcc
     6181 attgcacggc attggtcgtg gctatcaggc ggccgttctt ccatacctga aaagcttttg
     6241 tggccggcat cttcgtccag ctcaatgtgc ggccgtcgta gctcacgtcg ggcgcaggca
     6301 gcgtggtatg gttggctacg cggttgatcg ttccgcccgt tgcattattg gccagcacga
     6361 tgcggatggc atgatgcccc tgaagaccgg cggccagcgt ggcctgcgcc tgcttctttc
     6421 catcgagcca gaactctctg atgcggttgc cccagccatt catgtctatg tcgagaacgg
     6481 cgcggcggta cctgaaatta ttgagactgc gcttgcccgc aaatacccgc gggacaaagg
     6541 gttcgaagga cagtccgtcc tcgttgaagc gcacgccgaa aagcaccttg tgcacgatac
     6601 tgatattgcc cgacaggctc cagagcatat tgctcgaatt gatctgcgtg cccgcgaagt
     6661 cgccgttgtc ggccacgaag ttttccttat tggtagcgaa gagcgcagcg gggcgataga
     6721 tggcggccat gctttcggta acggcctttt cattgccggc ttttgcggcg gcccagagcc
     6781 agtaggtttg cacgaagggc cacacggcat tattgtgata gggcggaata tcgggtatct
     6841 ggggatagat gcaggagatg ccgtaagcgg tctgcggcac atgcgccacg atgttccttg
     6901 cgcgatcctc aggagcgatg ccgaagatca cgcaaagcgc ttcgccaagg gcttcggcgc
     6961 ggggcgaaag caggcggctg ttgcgcccgt agatatactg gccgtagtat tgctgctgcg
     7021 gcagccacag gtaattgttg atggcctttt tgatccgttc ggctacagcg ccgtagcgtg
     7081 ccgcttcggc gggatggttg agggcggcgg ccatgcgggc cagcacgttg ttggcctggt
     7141 agtgaacggc attggtgccg aggcattcgg attcggcgat gtccacgggc tgcatccact
     7201 tgggataggt ctgctcgcgc cagtcgagga aggaagactc acccttcacc agtcccgttg
     7261 cgggattgta agctacgtga ctgtcgtcgt cgatggagtt tttgatgatg acgtaggcct
     7321 gttgcagcca gtccttatcg ccggtgacct tgtagagttc ccaggcggcc acggcccaga
     7381 tggcgcggtc ggtactggcg ggccaggcgc cgccggtgcc cgtgtcctgg atgatctttt
     7441 tcttggcgct caccttgcgc agcaggcttt tcttcgccac ctcgggctgc aggtgggcca
     7501 tggcgaggat gatgctgtag ctgatgtcgc gggtccatac gccggcccat tccttgcctg
     7561 tgcggaaggt gctgtcgggt tcaacggcat tgatcatctc ctcaatcgca agattgtaaa
     7621 gggtgttggt gatcgtgaat ggcgaggtgt aggaaggaaa ggccgagagg tcgcggcgct
     7681 gccgccattc gggtgcggtt gcgggcgcat cgtcggattt gttgagcacg agggtcgctt
     7741 cgtagatgcc gtcgccgtcg cggtcgtgga gctgcagctg ctggtgattc acgaggttgt
     7801 cgaaatccca gatgaggggt gtggtattgc ccgccacgta tacgcccttg aaatccgttt
     7861 tatatatttt atcaccatta tatgtcgtgt agtagccttt tgtgtcgaag gcctggagta
     7921 cctcgcgcat gtcgaggcgg aaggtgagac gggtgccggc cggaagatag ccgccggcgg
     7981 gcttctggtt cagttgcgtg ccgaagcgga tgataggcgt ttcggcgctg ccgtcggtgg
     8041 ccgtataggt gaagtgatgg tcgatgcccg gcttcatctc gttgtccttg ccgttgatgc
     8101 taaacttgaa gccgatgttg acgctcttgt attcattggc cgcgctgcgg tagttggagc
     8161 ggagcgcccc gtccgagagg gcgtcggccc tgtagggtcc ctgcacgatg ctgtcccggt
     8221 agagctggta ggcgccggct tcataaatgg ggcggtcctg tgcgccggcg gagaaagcca
     8281 gcagggcgag agcgccggag gcaaagcgaa gtctattcat acaattcttt atttccccaa
     8341 atgagggttt caacccatga atttaggcaa agtgaagaaa gtgacgaaga gagcggagaa
     8401 agagaagcgg cacagggtct gtctcttcag aacataaacc ctgtaccggc cataaatttc
     8461 ttagaaatca aattcgaaat cgagcgccgg cgtctcgggc aggacaagcg agctatcgag
     8521 atcctctatg ggcccatgcg cgttctctat cagctgaacc agcacctttt catacttcat
     8581 cataagcacg tcgatggctt cggcggtcca tcgcttctta tcgtacgtga gcgtgcagcg
     8641 cagggcgtcg ccgtcctcgc ggaaattgac aagcaggggc aggcggctga agcgctgggc
     8701 tatgggcagg gcgctcaaac gcaggccctg cgccagctct atcgcatcgt agttgaagga
     8761 cagcggctga agcacgaaga gcacgtcgag gcgcaggcgg ctgtatatgt cggcgggcag
     8821 gtcctggtgc gcatcgatgc ccagcaggcc ggcctgcacc gatgccagca gctgcgtaaa
     8881 gctggcggcg gggtcgaggc gcacgcgcag cggcaaggtt tttacaaaca tgcccaattg
     8941 ctcgtgaaga ccctcgagcg tacggcccga gttgaccgtg ccgatacaca tatcctcatc
     9001 gccctcctgc ctgtgccata aaataaaaaa ggcggcggcc agaaaattat gcagcgtcgt
     9061 accctgccgc cgcacggcgc cgcgcagcga tgaaaagaag tcgccggtcc attcgaaatg
     9121 ctgttcgccg gcggccggct ccaatgaggc cgtgggtgcg gttttccagc gatgaccctc
     9181 gaggtagccg gtccagaagg tgcgatttgt ttcttccctt gcggcggcag cggtttccag
     9241 ccagtcgata taatcacgga actggaaggg cagcgcttca tccacacctt cgccgcggta
     9301 ctgatccacc actgcgcgca tcagtatttc tacggaccag ccgtccatga tgatgtggtg
     9361 cgtggcaaag gcaagaaagc ttcgcccctc ttttacaaac aagccggcgc gcagcagcag
     9421 gccgctttcc agatcgaagg gacgattcac atagtcttcc atggccgccc attcatcatc
     9481 ggcgggatcg atgcggtcga tggtaaagtc cgtggccgac acgaacagct gtgcggggcc
     9541 gccctcgcgc tcggcgaagc gcgtacgcag cacctcgtat ttttcgatca acctaaggaa
     9601 agcattttgc aggcgatcga tatcgagcgc acccgaaatt tcatagaggt tgaaaacatt
     9661 gtaggcggac gagcgctcct cattgccctg cgcggccagc cagatggcgt actgggcggg
     9721 cgtgagcggg taccagggcc gtggcgcgga caccgtaatg cctgtctgcg ctaccgcctg
     9781 ctgccggccg agatgaaggg ccagggcctg cacggtcggg aagtcgaaga cggtgcggag
     9841 ggccagcttg tactgcagcc ggttctccac caggtttacg agcttcatgg cattgagcga
     9901 atggccgccg agcgcaaaaa aatcgtcacc cgtatttata cgtatgctgt ggccgagcgc
     9961 ttccccgaaa agaccacaca gctgctcttc cagcgcggta gcgggcgccg cctcgggcga
    10021 ggcgacggct tcgatcgggc ggctggcgag ttgcttgcgg tctatctttt tattcggcgt
    10081 gagcgggaag ctatcgaggg gaacgatcac ctggggcacc atgtaggccg gcaggacttc
    10141 ctgcagcgcc gaccgtataa atacagtatc gatatctttt tcaccgggca cgacataagc
    10201 cacaagcacg acatcgccat tgcctttgtg ggccaccact accgacgcgt gcacggaggg
    10261 tagcgcatcg atcctcgact cgatctcgcc cagctcgatg cggtagccgc ggatcttcac
    10321 ctggtggtcg ttgcggccga ggaagtcgac agtgccgtcg gcggtccagc gcgcgaggtc
    10381 gccggtccgg tagatctttt tgccttcgtg aaagggatcg tcaataaagc gttcggccgt
    10441 aagctccggc gcccggtgat aaccttttgc aagaccgtcg cccccgatat ggagctcgcc
    10501 ggccatgccg acgggcagca gctgaccgca gtcgtcgaga atataaagct gcgtattggc
    10561 gatcggccgg ccgatgttgg atgactgttc ggggtccgtg atctttcgca ggctcgacca
    10621 aatcgtcgtt tccgtggggc cgtacatatt ccatagctcg gcgcagctgc gcaacagctg
    10681 tgcggccagc gcgctgccga ggagatcgcc gccgcacagc accttcaggc gctcgtcgcc
    10741 gggccagccc gcatcgaaga gcagttggta aagactgggc gtggcttgga tgatcgcggg
    10801 ccgcaaagcc tgcagccttg ccaccagcac cggcggattc agcaccacct cgcggccggc
    10861 aatgtaaata ctgcctccgg aaacaagcgg tccgaaaaac tcgagcattg aaatatcgaa
    10921 ggactgcgtg gtgaccgaaa aaaacagatc gccctccgca agccccggcc gccgctgcat
    10981 gctcaacaaa aaattgagca gcgagcgatg accgaccacc acgcccttgg gctggcccgt
    11041 cgagcccgaa gtataaatga tgtaggcatc gcccgacgaa gacacggttg gcagctcgct
    11101 attgctatcg ttcatggcgt cgatggaaat aaacggcgtc ccctcgaaaa ggtttttgaa
    11161 ttcatccgta ccggcaatgc aggccgcacg gctatgtccg acgatataac gcagtctatc
    11221 cgcgggaaaa gcgggatcga gcgggatgaa ggcccggccg cttttcagca cgccgagaag
    11281 aacggccacc aggcgcgccg agcgcggcat ca
//
