LOCUS       c00434_3300023..       11185 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300023267.a:Ga0247771_1000608.
ACCESSION   c00434_3300023..
VERSION     c00434_3300023..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 15:23:16
            Original ID  :: 3300023267.a:Ga0247771_1000608
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11185
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..591)
                     /locus_tag="ctg434_1"
                     /transl_table=11
                     /translation="MKPMLICLTALLFGFLTPGSLRAQGGGKISGRITDTSRALVPGAV
                     ASLTEVAGGKVIRNMLTTEAGLFSFAGLADGTYKVRVSCLGFLEASSEEIRVEGGTDRA
                     LEFRLMPDVKMLATIQVSAKRPVVEQRTDMTVLNVNETVRREAPNALEILKLAPGVIVS
                     DNEDEVTLTGKNAVQIMLNGHEVRLTGRDLLKLL"
     protocluster    1..11185
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[8273:11183](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(8274..11183)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..11185
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11185
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             complement(743..1705)
                     /locus_tag="ctg434_2"
                     /transl_table=11
                     /translation="MLPTTEVDEKITQLIGLLKQRLEPDGQNLSCFLEGLYHSRYPTYW
                     EYLQLELLLNLQHPRTSIPDELVFITYHQITELYFKLILAEIGQVTAREDIDAAFFAER
                     IGRVNRYLQNLVYSFDIMAGGMDREQFQAFRTALSPASGFQSYQFRVIEIISTGLANLR
                     ELRYRNETQGGPEAADLYDQIYWKQGATVTDTGKKDMSLILFERQYDPALRQRAADLRS
                     SNLEAQLSRIACDDPGYEHLRASLRTMDQLVNIDWRLSHFRSAARHLSAQNGDLKATGS
                     TNWRQYLPPRFQKLMFFPALWSAEERAEWGRSYVEALFQ"
     CDS             complement(1736..3463)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg434_3"
                     /sec_met_domain="PF00561 (E-value: 1.6e-09, bitscore: 26.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLRSLLAALAVLALGCAAHAQSGAIPAQYMSGQHWSRRIAWTRT
                     VDAASVPGLVDDNNNVDSAKLAASLRAMSESGGGVLDFGLGTYYFNFSLPVYDGAVIRG
                     ATAPDSAATPATRFIFPMLISKRGRRTDAERFVTYVPKVIFNATGHAAVIGLVNLDISR
                     AALVLDGSAGPRTSGSEPFIVDRLLLYNIRSNNAALLDPSIPTQKQIEGGQGWQIWADG
                     KAGNLNAFVGEGYTIARCRFNNAVTDSVLQHDFLTDDGMRYDGTEAQFRFAHHPAIRLR
                     TPQKFRGGELLDNSFRVVRGEEFVVVNEAPAPTQRNETLYLNETADLVLDGYRSASDTH
                     DLLFLDRFPSELKYFYGPHGDTLPYRLIRPEHYDQSKTYPLVVYLHDFWDKGNDGKKHL
                     RNFIWQLLTPENRAAYPCFIIAPQMPVDEPKWKPDGGLGSETWPLRATALIIERESEAL
                     PIDKKRVYMIGHSMGGAGAIHFTTHNPEKLAAMVAISAFYKFTPNAALQLAKVPSWLIY
                     GAQDNKIPLQLRQEIRLYLREAKANFKFTEVPGKAHRCWNTLTETTPELLPWLFAQHQ"
     CDS             complement(3489..5093)
                     /locus_tag="ctg434_4"
                     /transl_table=11
                     /translation="MKKELVYLKPNVVIEPLIDGWYAWSHLVSPATAAMNIEHRHLKIM
                     NSFIRSPEGHRLAVANPKLKGGPFMDIDPAKVEEVRMLRDETMDKREKMIAFSQAVREL
                     SQMLRQEAKGYSLQPLYARVPAPLRGYVELVYDLNNAPSFRFFEKLLYKSDYYDPASQS
                     IALWITENDERPFILTTPKLKSDNVLNVPVAFSDPFIDELSRMKRAPKPYEKIRDMVVL
                     QDENEERLFQSLFTTQVPPPYLPYTGNKARMRYFGHACILVEVSGISILVDPLVSYYGY
                     ESSIEHFSDFDLPERIDYVLITHNHQDHILFETLLPLRHRIGKIVVPKASGGTLQDPSL
                     KLMFEAVGFEHVEELGELDTLQFGDCAITGIPFLGEHSDLNIQSKICHHIRMRHFSMLF
                     VADSCNIEPLVYEHVHRELGDVDVVFLGMECDGAPLSWLYGPLLTDDLPRDKDQTRRLA
                     GSNYEQGAALVRVFNPKELYVYAMGQEPWLEFISSIKYTPDSNPIVASNKLIDECRRQG
                     LISERLFGEKEILYYIN"
     CDS             complement(5214..6875)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 114.9; E-value:
                     7.1e-35)"
                     /gene_kind="transport"
                     /locus_tag="ctg434_5"
                     /transl_table=11
                     /translation="MYMKRVIRHNRPFLIRVIALSIVNSALFGAIPLLISLIIRGEGLL
                     NFEPRQVWIPFLMLIAGSFLCRAVFQRDMIRFTNTVLFDLETTLLRQLNESDLENFNRL
                     DKSTVYTVFADIRTVSQLPRFFIDTVNYAVVILVSLIYLTWVSAAAALMLIGCAAFLAT
                     YYYVRNRSVARMLEGSRTLENQFYRYLGDLLAGFKGLKLNAERRTSMFDNFIHPNRSKA
                     CELEVSASTVYMNNELLGSYSWFIILGLIVFVLPLVTSFSMADSLSFIVIILYLMSPLS
                     ALINTLPFYTRISIAFKRIGRFIESNRKKTPPTAAVKETPAPLQQIRFEGVGYQYPPQT
                     DRQPFQIEGLDLDIRRGEVIFVTGENGSGKSTFLLLLTGLLQPHAGCLTVNGRPLEPAE
                     SEGYSSRFSAIFSDSILYSENYDGYALHPGNQVLMDHFSLMKLRTDIITRDATIRTELS
                     KGQQKRLALIYSLLEEREVLVLDEWAAEQDPHFRAYFYKNVLPELKRLGKTIIAVTHDD
                     KYFHLADRTFRFHQGSLTIESRASFSINGHTEGIWF"
     CDS             complement(6923..8251)
                     /locus_tag="ctg434_6"
                     /transl_table=11
                     /translation="MKLIFCPGRHALLPVLFALLCLNARAANSPALITDVRVTVDKTAQ
                     TLRVSYVLADKDNASATVQFLVSGDGGTTYAVATGNATGDVGKSVRTGRHSFTWSFAAS
                     GLRPGAIRFQLVADDGEAADPAELIRQVDTARLRKRLSSIAIPRDSETDTGRANLEQVR
                     KTIAGTFEKGQYALETQNFVFGDIHGRNIIGRKKGTQQDNLIYVLCASYDGMPNCPAAN
                     NNGSGVAGMMEIADILSRYSFRHTIVVLATDYTGEEFIGSNWFVFHGGIRDSDVMDGAI
                     DLDRIGTSSDAPNTHIIGESKPVLFPENCKAIEADSLRANFLKVISNNRSMPLVDVMQR
                     VARKYEPRLTNYVEEFPGYGEFSIGTEDYLQFSDHIAFWYNRYKAIWITDAREGIRRDN
                     TPDDTIDKLNFRFMGQAVRIALGTLIDLAGLQHSTTYRGVFRL"
     CDS             complement(8274..11183)
                     /NRPS_PKS="Domain: Condensation_DCL (5-222). E-value:
                     4.7e-68. Score: 221.2. Matches aSDomain:
                     nrpspksdomains_ctg434_7_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (386-778). E-value: 4.8e-95.
                     Score: 310.2. Matches aSDomain:
                     nrpspksdomains_ctg434_7_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (882-950). E-value: 2.8e-20. Score:
                     64.1. Matches aSDomain: nrpspksdomains_ctg434_7_PCP.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     335.7; E-value: 6.7e-102)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg434_7"
                     /sec_met_domain="Condensation (E-value: 4.8e-49, bitscore:
                     155.9, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2e-107, bitscore:
                     348.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.1e-15, bitscore:
                     45.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="ERAPEFRCIDLPAGTDTQQALETFLTEDRDRRFDLRRDVLMRLTL
                     FQQGTDRSIFVWSYHHILMDGGCTPILVAEFNRIYAALASGVEVALPAPAPYRRYIEWL
                     ERQDRKISSAFWKSYLDGFEGNPALPGRMPGRHTDNRQVEVQCNFTLQETAALRAAALG
                     QRVTFNNYLSTVWGLLLSLYGNQRDVVFGTVSMVRPVEVEGIGNMVGLFINTTPWRLRY
                     DAGDTFETLLQAQSRQRSESLRHQYFPLADIQSATPLGNRLFDHLFVISSELGLPASAS
                     GDTQPQFAVAGVRSIEEVNYGFSVHAGVGAELRIHFTYRTGAVDGAWVENLARHFRRLL
                     FAVSQSPTLPLDRIQVLDSEEIKDLLTLGDGPVRDYSGTIIDHVLKTVQEHGGRTAVVC
                     ESGNLTYDELDNRSTLLALELEKRGLRPGDVVGVLCQRRASWIAAILAIWKAGGTYLPL
                     DRAHPDVRLLLQLEDAQCRLLLTDEEEAGRLQEATVPRLVLDLPLTPSLLPDRSPYRGC
                     TPQQTAYIIYTSGTTGKPKGVPITQASLVETIAWHNEYFSMQEGEGVLQFASCGFDASL
                     VEIFMALLSGGRLVLLPERIKNNTGHFAGFLQQHRVHLAILPPAYIRLFSAEDLPGLTK
                     IISTGEEAAWDRMIKLSRGRMVCNGYGPTETCVGACFHRVRSERSEEYRATRNIPIGRP
                     FANRRILVLDADGRLLPKGASGEICIGGPGISAGYIGEAALTAERFIEDPYHPGQRLYR
                     TGDRGRWDAAGELLFEGRYDNQVQLHGIRVELGEVESALLRFPGVRQACTRLLYRGGEP
                     FLAAYIQVDEQLDEQELSVHLYRHLPAHMVPAWCKQLPLFPTTSNGKIDVAALPQPGDI
                     SSTHRAPLTPTEEAVCQIFARVLERESTGAADNFFLSGGHSIRGIRLLTQIEKKFDLSI
                     SLKHLFEHPTPELLSRYIDARLWARNALLPADDTESVII"
     aSDomain        complement(8334..8537)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg434_7_PCP.1"
                     /evalue="2.80E-20"
                     /label="ctg434_7_PCP.1"
                     /locus_tag="ctg434_7"
                     /protein_end="950"
                     /protein_start="882"
                     /score="64.1"
                     /tool="antismash"
                     /translation="EEAVCQIFARVLERESTGAADNFFLSGGHSIRGIRLLTQIEKKFD
                     LSISLKHLFEHPTPELLSRYIDAR"
     aSModule        8334..11168
                     /complete
                     /domains="nrpspksdomains_ctg434_7_Condensation_DCL.1"
                     /domains="nrpspksdomains_ctg434_7_AMP-binding.1"
                     /domains="nrpspksdomains_ctg434_7_PCP.1"
                     /locus_tags="ctg434_7"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(8817..8879)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg434_7_0008"
                     /evalue="1.90E-07"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg434_7"
                     /protein_end="789"
                     /protein_start="768"
                     /score="23.5"
                     /tool="antismash"
                     /translation="EGRYDNQVQLHGIRVELGEVES"
     aSDomain        complement(8850..10025)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg434_7_AMP-binding.1"
                     /evalue="4.80E-95"
                     /label="ctg434_7_AMP-binding.1"
                     /locus_tag="ctg434_7"
                     /protein_end="778"
                     /protein_start="386"
                     /score="310.2"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="TVQEHGGRTAVVCESGNLTYDELDNRSTLLALELEKRGLRPGDVV
                     GVLCQRRASWIAAILAIWKAGGTYLPLDRAHPDVRLLLQLEDAQCRLLLTDEEEAGRLQ
                     EATVPRLVLDLPLTPSLLPDRSPYRGCTPQQTAYIIYTSGTTGKPKGVPITQASLVETI
                     AWHNEYFSMQEGEGVLQFASCGFDASLVEIFMALLSGGRLVLLPERIKNNTGHFAGFLQ
                     QHRVHLAILPPAYIRLFSAEDLPGLTKIISTGEEAAWDRMIKLSRGRMVCNGYGPTETC
                     VGACFHRVRSERSEEYRATRNIPIGRPFANRRILVLDADGRLLPKGASGEICIGGPGIS
                     AGYIGEAALTAERFIEDPYHPGQRLYRTGDRGRWDAAGELLFEGRYDNQVQLH"
     CDS_motif       complement(8964..9053)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg434_7_0007"
                     /evalue="3.00E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg434_7"
                     /protein_end="740"
                     /protein_start="710"
                     /score="38.7"
                     /tool="antismash"
                     /translation="PKGASGEICIGGPGISAGYIGEAALTAERFI"
     CDS_motif       complement(9561..9617)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg434_7_0006"
                     /evalue="3.70E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg434_7"
                     /protein_end="541"
                     /protein_start="522"
                     /score="28.6"
                     /tool="antismash"
                     /translation="AYIIYTSGTTGKPKGVPITQ"
     CDS_motif       complement(9807..9848)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg434_7_0005"
                     /evalue="1.90E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg434_7"
                     /protein_end="459"
                     /protein_start="445"
                     /score="17.8"
                     /tool="antismash"
                     /translation="LAIWKAGGTYLPLDR"
     CDS_motif       complement(10377..10475)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg434_7_0004"
                     /evalue="6.00E-12"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="ctg434_7"
                     /protein_end="269"
                     /protein_start="236"
                     /score="37.9"
                     /tool="antismash"
                     /translation="RQRSESLRHQYFPLADIQSATPLGNRLFDHLFVI"
     aSDomain        complement(10518..11168)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg434_7_Condensation_DCL.1"
                     /domain_subtype="Condensation_DCL"
                     /evalue="4.70E-68"
                     /label="ctg434_7_Condensation_DCL.1"
                     /locus_tag="ctg434_7"
                     /protein_end="222"
                     /protein_start="5"
                     /score="221.2"
                     /tool="antismash"
                     /translation="FRCIDLPAGTDTQQALETFLTEDRDRRFDLRRDVLMRLTLFQQGT
                     DRSIFVWSYHHILMDGGCTPILVAEFNRIYAALASGVEVALPAPAPYRRYIEWLERQDR
                     KISSAFWKSYLDGFEGNPALPGRMPGRHTDNRQVEVQCNFTLQETAALRAAALGQRVTF
                     NNYLSTVWGLLLSLYGNQRDVVFGTVSMVRPVEVEGIGNMVGLFINTTPWRLRYD"
     CDS_motif       complement(10527..10622)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg434_7_0003"
                     /evalue="1.00E-12"
                     /label="C5_DCL_263-294"
                     /locus_tag="ctg434_7"
                     /protein_end="219"
                     /protein_start="187"
                     /score="40.5"
                     /tool="antismash"
                     /translation="DVVFGTVSMVRPVEVEGIGNMVGLFINTTPWRL"
     CDS_motif       complement(10860..10898)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg434_7_0002"
                     /evalue="1.10E-03"
                     /label="C4_DCL_171-183"
                     /locus_tag="ctg434_7"
                     /protein_end="108"
                     /protein_start="95"
                     /score="11.5"
                     /tool="antismash"
                     /translation="PYRRYIEWLERQDR"
     CDS_motif       complement(10944..11009)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg434_7_0001"
                     /evalue="1.50E-07"
                     /label="C3_DCL_135-156"
                     /locus_tag="ctg434_7"
                     /protein_end="80"
                     /protein_start="58"
                     /score="23.9"
                     /tool="antismash"
                     /translation="YHHILMDGGCTPILVAEFNRIYA"
ORIGIN
        1 gagcagcttc agcaggtcgc ggccggtgag gcgcacctcg tggccattga gcatgatctg
       61 aaccgcattc ttgccggtca gtgtcacttc gtcctcgttg tcggatacga tcacgcccgg
      121 cgcgagcttc agtatctcca gcgcattggg cgcttccctg cgaacggttt cattcacatt
      181 cagcacggtc atgtcggtcc tttgctccac taccggtctt ttggcgctta cctggatggt
      241 ggccagcatc ttcacatcgg gcatcaagcg aaattccagc gcacggtccg ttccgccctc
      301 caccctgatc tcctcgctcg acgcttcgag aaatccgagg cagcttaccc gcaccttgta
      361 ggttccatct gcaagaccgg caaaagaaaa caggccggct tccgtggtca gcatattgcg
      421 aatgaccttg ccgccggcaa cctcggtaag cgaggccacg gcgccaggca ctagtgccct
      481 ggaggtgtcg gtgatgcggc cggaaatctt gccgccgccc tgggcgcgca ggcttcccgg
      541 cgttaaaaac ccaaagagca gggccgtcag gcagatgagc atcggtttca taacagtcgt
      601 tttggtaaag tgagtacaaa gcgggatcgt aatcgccgca aatcataatt tgaggcaagc
      661 gcaaccggtc tcaaatctta aaagtttgaa cgtcagaatg ttggatcggc ataatgcagg
      721 atttgagacc tgcccgccat cgttattgaa acagggcctc cacataggaa cgtccccatt
      781 cggcccgctc ttccgccgac cacagggcag ggaagaacat caatttctgg aacctgggtg
      841 gcaggtactg ccgccagttg gtgctgccgg ttgctttaag gtcgccgttc tgggcgctca
      901 ggtggcgtgc agccgatcgg aaatgcgaga gtcgccagtc gatgttgacc agctggtcca
      961 tggtccggag cgaggcgcgg aggtgctcgt aacccggatc gtcgcaagcg atcctggaca
     1021 gctgcgcctc gagattcgac gaccggagat cggccgcccg ctgccgcagc gccgggtcgt
     1081 actgccgttc gaaaaggatc aggctcatat cttttttgcc ggtatcggtt accgtcgcgc
     1141 cctgcttcca gtagatctgg tcgtacaggt cggccgcttc ggggccgccc tgcgtttcat
     1201 tgcggtagcg cagctcgcgg aggttagcca ggccggtaga gatgatctcg atcacccgga
     1261 actggtacga ctgaaagccg cttgccggcg aaagcgccgt gcgaaaagcc tggaactgct
     1321 ccctgtccat tccacccgcc atgatgtcga aagaatagac aaggttttgc aggtagcggt
     1381 tgacccgccc gatgcgttcg gcaaagaagg cagcatctat gtcctcgcgc gctgttacct
     1441 gcccgatctc ggcgaggatc agcttgaaat acagctcggt gatctggtgg taggtgatga
     1501 acaccagctc gtcggggatc gaggtacgcg ggtgttggag attgagcagc agctccagtt
     1561 gaagatattc ccagtaagtg ggataccggc tatggtacag tccttcgaga aagcaggaaa
     1621 gattctgccc gtcgggctcg agtctttgct tcagcaggcc gatcagctgc gtaatttttt
     1681 cgtcgacttc agttgtggga agcatggcag gaattttatt atccggtgcg tccggttatt
     1741 ggtgttgtgc aaaaagccag ggcagcagtt cgggcgttgt ttcggtaagc gtgttccagc
     1801 accggtgtgc ctttcccggc acttcggtga atttgaaatt ggccttggct tcacggaggt
     1861 acaagcggat ttcctgccgg agctgcagcg gtatcttgtt gtcctgcgca ccgtaaatga
     1921 gccagctggg cacctttgcc aactgcagcg cggcgttggg agtgaacttg taaaaggccg
     1981 atatcgccac catcgcggcc agcttttcgg ggttgtgcgt ggtgaaatgg atggcgcccg
     2041 cgccgcccat ggagtgcccg atcatgtaaa cccgtttttt atcgatgggg agcgcttccg
     2101 attcgcgttc gatgatcagc gccgtggcgc gcagcggcca ggtttcgctg cccaaaccgc
     2161 cgtcgggctt ccacttcggc tcgtcgaccg gcatttgtgg tgcgatgata aagcagggat
     2221 aggcggccct gttttccggc gtcagcaatt gccagataaa attgcgcaag tgctttttcc
     2281 catcgttccc tttgtcccag aaatcatgca ggtatactac cagcgggtag gtcttcgact
     2341 gatcgtaatg ctccgggcgg atgaggcggt aaggaagggt atcgccgtgc gggccgtaaa
     2401 aatatttcag ctcggaaggg aagcggtcga ggaaaagcag gtcgtgcgtg tcgcttgccg
     2461 agcggtagcc gtcaagcacc agatcggcgg tctcgttaag gtagagggtc tcgttccttt
     2521 gtgttggggc cggcgcttcg ttgaccacga cgaactcttc tcccctcact acgcgaaagc
     2581 tgttgtcgag gagctcgccc ccgcgaaatt tctgcggcgt gcgtagccgg atcgcggggt
     2641 ggtgagcaaa acggaactgc gcttccgtac cgtcgtaacg catgccgtcg tccgtgagaa
     2701 aatcgtgctg caatacgctg tcggtaacgg cattgttgaa ccggcagcgc gcgatggtgt
     2761 agccctcgcc gacaaatgcg ttgaggttgc cggccttgcc atcggcccat atctgccatc
     2821 cctgtccgcc ttcgatctgc ttttgcgtcg ggatcgacgg gtcgagcagg gccgcgttat
     2881 tgctgcggat attgtacaga agcaggcgat cgactataaa gggttcgctc ccgctagtgc
     2941 gcggaccggc gctgccgtcg aggacgagcg ctgcgcggct gatgtcgagg ttgaccaggc
     3001 cgatcacggc agcgtggccc gtggcattga agatcacctt cggcacatag gtcacaaagc
     3061 gttcggcatc ggtgcggcgg ccgcgtttcg agatcagcat gggaaagatg aagcgggtcg
     3121 cgggagttgc ggcgctgtca ggggctgtag cgccgcggat aacggcgcca tcgtacaccg
     3181 gcaggctgaa gttgaagtaa tacgttccga gcccgaagtc aagcacgccg ccgccgctct
     3241 ccgacatggc gcggaggctt gcggcaagct tggcggaatc gacattgtta ttgtcgtcga
     3301 ccagccccgg taccgaagcg gcatccactg tgcgcgtcca ggcgatgcgg cgggaccaat
     3361 gctgtcctga catgtactgt gccgggatcg cgccggactg cgcgtgtgcg gcacatccca
     3421 gcgccaggac ggccagcgcc gcgagtaagg atcgaagatt cataaaaaag atagtttagg
     3481 taaagaggtc agttgatgta ataaaggatt tccttttcgc caaaaagccg ttcggagatg
     3541 agcccctgcc gccggcactc gtctatcagc ttgttggacg cgacgatcgg gttcgagtcg
     3601 ggggtgtatt tgatcgatga aataaattcc agccacggct cctgtcccat cgcatatacg
     3661 taaagctcct tgggattgaa cacgcgaacc agcgcggcgc cctgctcgta attggagccg
     3721 gccagtcgac gggtctggtc cttgtcgcgt ggcaggtcgt cggtgagcag ggggccatag
     3781 agccaggaaa gcggcgcgcc gtcgcactcc atgccgagga acaccacatc cacgtctccg
     3841 agctcacggt gaacgtgctc atacacgagg ggttcgatgt tgcaggagtc ggccacgaaa
     3901 agcatcgaaa agtggcgcat gcgtatatgg tgacagatct tgctttggat gttcaggtcg
     3961 gaatgctcgc cgaggaaagg aatgcccgtg atggcgcagt cgccgaattg cagcgtatcc
     4021 agctccccga gctcttccac atgctcgaac ccgacggctt cgaacataag cttcaggctc
     4081 gggtcctgca gggtaccgcc cgaagccttg ggcaccacga tcttgccgat gcggtgacgc
     4141 agcggcaaca gcgtttcgaa gaggatatga tcctggtgat tgtgggtgat cagcacataa
     4201 tcgatgcgct cgggcaggtc gaaatcggag aaatgctcaa tgctcgattc gtaaccgtag
     4261 tagctcacca gcggatcgac caggatggaa attccgctga cctcgacaag gatgcaggca
     4321 tgaccgaaat accgcatccg ggccttgttg ccggtatagg gcaggtaggg cggcggcacc
     4381 tgggtggtga acagcgattg aaaaaggcgt tcctcgttct catcctgcaa cacgaccata
     4441 tcgcgtattt tttcgtaagg cttcggcgcc cgcttcatcc ggctcagctc atcgatgaac
     4501 gggtcggaga aagcaaccgg cacgttcagc acgttatccg atttgagctt gggcgtcgtg
     4561 aggatgaaag gccgttcatc gttctcggtg atccacagcg cgatgctctg cgaagccgga
     4621 tcgtagtagt cgctcttgta cagcagcttc tcgaaaaacc tgaacgaggg cgcattgtta
     4681 aggtcataca ccaattccac gtaaccccgc agcggagcgg gtacccgcgc ataaagaggc
     4741 tgcagcgagt agcccttcgc ttcctgacgc agcatctggc tcagttcgcg aacggcctgt
     4801 gaaaacgcga tcatcttttc gcgcttgtcc atcgtttcat cgcgcagcat ccgcacttcc
     4861 tccacctttg ccgggtcgat gtccatgaaa ggaccgccct tcagcttggg gttggccacg
     4921 gcgagccggt ggccttcggg cgaacggatg aatgagttca tgatcttcag gtgccggtgc
     4981 tcgatgttca tggcggcggt tgccggagac acaaggtgcg accacgcgta ccatccgtcg
     5041 atcagcggtt cgatgaccac gttgggcttg agataaacaa gttccttttt catgtaagag
     5101 attttagtgt gatgttgaaa agctgcgctg ccggtgctgc ttgcgaaaaa tgaaaaatat
     5161 attcggccgg cagcgtgcac agggctgccg cccgtgaaat gaaaagcaaa aggtcagaac
     5221 cagatacctt ccgtatggcc gttaatgctg aaggatgccc gcgattcgat cgtcaggctg
     5281 ccctggtgaa agcggaaggt gcggtcggcg aggtggaagt atttgtcgtc gtgcgttacg
     5341 gcaatgatcg ttttgcccag gcgcttcaat tcgggcagca cgttcttgta gaagtacgcg
     5401 cgaaaatgcg gatcctgctc ggccgcccat tcgtcgagca ccagcacttc ccgttcttca
     5461 agaagggaat atatcaacgc cagccgcttc tgctgtcctt tcgataattc ggtgcggatg
     5521 gtagcgtcgc gcgtgatgat atcggtgcgc agcttcatca ggctgaaatg atccatgagc
     5581 acctggttac cgggatgaag ggcgtagccg tcgtagtttt cgctgtacag gatgctgtcg
     5641 gaaaagatcg cggagaaacg gctggaatat ccttcgcttt cggcgggttc cagcgggcgt
     5701 ccgttgacgg tgaggcagcc tgcgtgcggt tgcagcaaac cggtgagcag aagaaggaag
     5761 gtgcttttgc cgctgccgtt ctcgccggtc acgaagatca cttcgccacg ccggatgtcg
     5821 aggtcgaggc cttcgatctg gaacggttgc cggtcggtct gcggaggata ctggtagcct
     5881 acgccttcga agcggatctg ctgcaagggt gcgggcgtct ccttgacggc agccgtgggc
     5941 ggcgtttttt tgcggttgct ctcgatgaac cggcctatgc gcttgaaggc gatcgatatc
     6001 cgggtgtaga atggcaatgt gtttatcaag gcgctcaacg gcgacatcag gtaaaggatg
     6061 atgacaatga acgatagcga atcggccatg gagaacgagg taacaagcgg cagcacgaac
     6121 acgatcaggc ccaggataat gaaccagctg tagctgccca gcaattcgtt attcatgtac
     6181 accgtggatg cgctcacctc aagctcgcag gccttgctgc ggttcgggtg aatgaaattg
     6241 tcaaacatgc tcgtgcgccg ctctgcattc agcttaaggc ctttgaagcc cgcaagcagg
     6301 tcgccgagat agcggtaaaa ttgattctcc agcgtcctcg acccttcgag catgcgggcc
     6361 accgagcggt tgcggacata atagtaggtg gcgagaaaag ccgcgcagcc tatgagcatg
     6421 agggcggccg cggccgatac ccaggtgagg taaataaggc tgacgaggat cacgaccgca
     6481 tagtttaccg tgtcgatgaa aaagcgcggc agctgcgaga ctgtccggat atccgcgaac
     6541 acggtgtata ccgtcgactt gtcgagccgg ttgaaattct caaggtccga ttcgttcaac
     6601 tgccgcagca gcgtggtttc caggtcgaaa agcacggtgt tggtaaagcg gatcatgtca
     6661 cgctgaaaaa cagcacggca aagaaaggaa ccggcgatca gcatcaggaa ggggatccac
     6721 acctggcggg gttcgaaatt caacaagccc tcgccgcgta tgatcaggct gatgaggagc
     6781 ggaatggcgc cgaacagcgc actgttgaca atgctgaggg cgatcacccg tatcaggaaa
     6841 ggacggttgt ggcgaatcac gcgcttcatg tacatggaaa taatttgaag gttctgaatt
     6901 gggcatcagg catcacgacg gatcataagc ggaacactcc ccgataggtg gtgctgtgct
     6961 gcaggccggc caggtctatg agggttccga gggcgatacg tacggcctgc cccataaacc
     7021 ggaagttgag cttgtcgatg gtatcgtcgg gcgtgttgtc gcgcctgatg ccctcgcggg
     7081 catcggtgat ccagatcgcc ttgtagcggt tataccaaaa agcaatatgg tcgctgaact
     7141 gcagatagtc ttcggtgcct atcgagaatt cgccatagcc gggaaactct tcgacatagt
     7201 tggtcagcct gggctcgtac ttgcgggcaa cccgctgcat cacgtccacc aacggcatcg
     7261 accggttgtt gctgatcact ttcaggaaat tggcccgcag gctgtcggcc tcgatggcct
     7321 tgcagttttc ggggaagagc accggcttgc tttcgccgat gatgtgggtg ttgggcgcat
     7381 cgctgctggt gccgatccgg tccaggtcga tcgctccgtc catgacgtcg gaatcgcgga
     7441 tgccgccgtg aaagacgaac cagttgctgc cgatgaactc ttcgccggta taatcggtgg
     7501 ccagcactac gatagtgtgg cgaaacgaat accgcgagag gatgtcggcg atttccatca
     7561 tcccggccac gccggatcca ttgttgttgg cggcgggaca attgggcatc ccgtcataag
     7621 atgcgcaaag cacatagatc aggttatcct gctgcgttcc ctttttccgg ccgatgatgt
     7681 tccggccatg gatatctccg aatacgaagt tttgcgtttc gagcgcgtac tgcccttttt
     7741 caaaggtgcc cgcaatggtt ttccgcacct gctccaggtt ggcgcgcccg gtgtccgttt
     7801 cactgtcgcg cggaatggcg atgctgctga gccgtttacg cagccgcgcg gtatctacct
     7861 ggcggatgag ctccgcgggg tcggcggctt cgccgtcgtc ggccaccaat tgaaaacgga
     7921 tcgcgccggg ccggaggccg ctggcggcga agctccacgt gaaggaatgg cggcccgtgc
     7981 gcacgctctt gcccacatcg cccgtggcat tgccggtggc gacggcataa gtggttccgc
     8041 catcgccgga tacgaggaac tgaacggtcg ccgaagcatt gtccttatcc gccagcacat
     8101 agcttacgcg gagggtttgc gcggtcttgt ccacggtaac gcgcacgtcg gtgatcaggg
     8161 ccggcgagtt ggctgcgcgc gcgttcaggc aaagcaaggc aaaaaggacc ggcagcaggg
     8221 catgacgccc ggggcaaaaa ataagtttca taaaaattat tataaataaa aaattatata
     8281 attaccgatt cggtatcgtc ggccggcagc agcgcattgc gcgcccacaa gcgggcgtcg
     8341 atgtaccggg aaagcagctc gggcgtgggg tgttcaaaca ggtgcttgag cgaaatgctc
     8401 agatcgaact ttttttcaat ctgggtcagg agcctgatgc cgcggatcga gtggccgccg
     8461 ctcaggaaaa agttatcggc agcgcccgtg ctctcccgct ccagcacgcg tgcaaagatt
     8521 tggcagactg cttcctcggt gggcgtcaac ggtgcgcggt gcgtggaact gatatctccc
     8581 ggctgcggca gcgcggcgac atcgatcttg ccgttggacg tagtgggaaa gagcggcagc
     8641 tgcttgcacc atgccggtac catgtgggcc ggcaggtgcc ggtaaagatg caccgacagc
     8701 tcctgctcgt cgagctgctc gtccacctga atataggcgg caagaaaagg ttcgcccccg
     8761 cggtacagga gccgcgtgca ggcttgccgt acgccgggaa accgcagcag cgccgactcc
     8821 acttccccga gctccacgcg tatgccgtgc agctgcacct ggttgtcgta ccgcccttcg
     8881 aacagcaact cgccggcagc atcccaccgc ccgcgatcgc cggtgcggta aaggcgctgg
     8941 ccgggatgat acgggtcttc gatgaagcgc tcggcagtaa gtgccgcctc gccgatataa
     9001 cccgccgaga taccgggacc gccaatgcaa atttctccgg atgcgccctt cggcagaagc
     9061 cggccatcgg catccagcac cagtatccgc ctgttggcga aaggccgccc tattggaatg
     9121 ttccgcgttg cccggtattc ttccgaacgc tcggaccgca cccggtgaaa gcaggcgccg
     9181 acgcaggttt ccgtcggccc atagccattg caaaccattc gtccgcggct tagtttgatc
     9241 atgcggtccc atgctgcctc ctcgccggtg gaaatgatct ttgtcaatcc cggcagatct
     9301 tccgcgctga agagacggat ataggcagga ggcagaatgg ccaggtggac ccgatgctgc
     9361 tgaagaaaac cggcaaagtg acccgtgtta tttttaatgc gctccggcag caggaccagg
     9421 cggccgccac tcagcaaagc catgaaaatt tcaaccagcg aggcatcgaa accgcaggat
     9481 gcgaattgca gcacgccttc cccctcctgc atggaaaagt attcgttgtg ccacgcaatg
     9541 gtctccacca gcgaagcctg cgtgatcggc actcctttcg gtttcccggt cgtgcccgac
     9601 gtgtagatga tgtaagccgt ttgttgaggc gtgcatccgc ggtacgggct tcggtcagga
     9661 agcagcgatg gcgtcagcgg caggtcaagt accaggcgcg gcacggtcgc ctcctgtagc
     9721 cgcccggcct cctcttcgtc cgtcaatagc aggcggcact gcgcatcctc gagctgaaga
     9781 agcaggcgta cgtcggggtg ggcgcggtcg agaggaagat aggtgccgcc ggccttccat
     9841 atcgccagga tggctgcgat ccaggatgcc cggcgctggc aaagaacccc cactacgtcc
     9901 cccggacgaa gcccgcgctt ttccagttcc agtgctagca aggtgctccg gttgtccagt
     9961 tcatcgtacg taaggttgcc gctttcgcag actaccgccg tccggccgcc atgctcctgc
    10021 actgttttca ggacgtgatc gatgattgtg ccggagtagt cgcgcacagg gccgtcgcca
    10081 agcgtcagca ggtcttttat ttcttcgctg tccagtactt gtatccggtc gagcggcagc
    10141 gtggggcttt gggagacggc aaacagcaag cggcggaagt ggcgggccag gttttcgacc
    10201 catgctccat cgacagcgcc ggtgcggtaa gtgaaatgga tccgcaactc cgctcctacg
    10261 ccggcatgca cgctgaagcc gtaattgacc tcttcgatac tgcgtacgcc ggcaactgcg
    10321 aactgcggct gcgtgtcgcc ggaagcggaa gccggaaggc caagctccga gctgatcacg
    10381 aaaaggtgat cgaacaaacg gttgcccagg ggcgttgcgg attgaatgtc ggcgagcgga
    10441 aaatactgat gccgcaggct ctccgaacgc tggcggctct gggcctgcaa cagggtttcg
    10501 aacgtatcgc cggcatcgta gcgaagccgc cagggagtcg tgttaatgaa cagtccgacc
    10561 atattgccga tgccttcaac ttcgaccggg cgcaccatgg aaacggtgcc gaagaccacg
    10621 tcgcgctggt tgccataaag agaaagcagc agtccccaga ccgtcgacaa gtaattgttg
    10681 aatgtaacgc gctggccgag cgccgctgcg cgcaatgccg ccgtttcctg caaggtaaaa
    10741 ttgcattgaa cctcaacctg cctgttgtcc gtatgcctcc cgggcatgcg gcccggaagt
    10801 gcggggtttc cctcaaagcc atcgagatag gatttccaga atgccgacga gatcttgcgg
    10861 tcctgccgct ccagccattc gatgtaccgg cggtagggcg ccggcgccgg caacgcgacc
    10921 tcgacgcccg aggccaacgc tgcgtaaatg cggttaaact cggcgacaag gatcggggtg
    10981 catccgccat ccatcaggat gtggtggtag ctccatacga agatcgaacg gtcggttccc
    11041 tgctgaaaca gggtcaaacg catcaataca tccctgcgca gatcgaaacg gcggtcacgg
    11101 tcctccgtaa gaaaggtttc gagggcctgc tgcgtatctg tgcctgccgg cagatcgatg
    11161 caccggaact cgggcgcgcg ttcac
//
