LOCUS       c00061_3300024..        3340 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300024186.a:Ga0247688_1001886.
ACCESSION   c00061_3300024..
VERSION     c00061_3300024..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 09:28:56
            Original ID  :: 3300024186.a:Ga0247688_1001886
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3340
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3340
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:3338](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(3..3338)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..3340
                     /SMILES="N1C(CCC1)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3340
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             complement(3..3338)
                     /NRPS_PKS="Domain: AMP-binding (1-312). E-value: 2.1e-72.
                     Score: 235.6. Matches aSDomain:
                     nrpspksdomains_ctg61_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (423-490). E-value: 4.5e-29. Score:
                     92.2. Matches aSDomain: nrpspksdomains_ctg61_1_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (514-816). E-value:
                     4.3e-119. Score: 388.6. Matches aSDomain:
                     nrpspksdomains_ctg61_1_Condensation_LCL.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 95.4;
                     E-value: 4.4e-29)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_1"
                     /sec_met_domain="Condensation (E-value: 2.8e-85, bitscore:
                     272.1, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-88, bitscore:
                     283.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.6e-20, bitscore:
                     58.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="AGARVVLTQQSLAQRLPEQSPHVVRLDADWATIAQERAQNPENVA
                     TPDSAAYVIYTSGSTGLPKAVVMPHRGAVNLINYQIQSAGKPLRTLQFASLSFDVSFQE
                     IFPTLCSGGSLVLLREDVRRDAAELWRLIAEQRVQRLFLPFVALQHLAEEAGRQESVPS
                     SLRQVITAGEQLKITPQVARLFQRLDGCTLDNHYGPTETHLATAWRLEGDAGSWSRLPP
                     IGKPITNAQAYVLDDALQLVPAGVTGELYIGGAQLARGYLNRPDQTAERFIPNPFDHHG
                     SRLYRTGDLARYAANGVLGYAGRRDLQVKVRGFRVEVGEIEAVLKQHGSVKQAVVTAAE
                     DEAGRKRLVAYIIAARGSASPTREELRSHLKDKLPEYMIPSLFLLLDAFPLTGSGKVDR
                     RALPAPDAEHAALAEAIVAPRSGVEEMLASIWSEVLGGVRVGVKDNFFDLGGHSLLATQ
                     VMSRVREAFGIEIALRSLFEQPTVGELAETIGELLAAKAGMPRQVESVKRAQREGNAVP
                     LSFAQQRLWFLDKLEQDSSFYNLSSIVRICGAKLDAGALEKSLREVTQRHEVLRTTFTI
                     IDQQPVQVISPESQFTLPVVELGHLPPAERNAAAQRLEREETERRFDLSTGPIIRARLL
                     RLSSEEHVLILSMHHIASDGWSTSVLIREVAALYEAYASGVESPLKELNIQYGDFAVWQ
                     REWLQGEVLDQQLAYWRKQLAGAPPVLELPTDYPRPAVKTFNGAALPLRLPRSLSDALT
                     ALSRREGVTLFMSLLAAFQLLLWRYSGQDDISVGTAVANRTRAETEELIGFFVNTLVLR
                     TDVSGNPTFRELVQRVRETALGAYAHQDIPFEKLVEELATERNLSFTPLFQVVFALQNT
                     PSPEFRLRDLQLTLLETERDIAKFDLSLVMWETAEGLEGTLEYNTDLFETGTMQRLLRH
                     FRTLLEGIVANPDALIADLPLLTASERAQLLVEWNDTQRPFARELCIHELFESQAAKSP
                     QATAVVFADQQLSYEELNTRANRLAHQLKALGIGPEQRVGVLLERSLEMPLAVVSVLKA
                     GGTYVPLDPAWPSERLRWIASSLGIRCLLTQSAQLRAVHELQWKLPQLTDVICLDVDTQ
                     RPPAE"
     CDS_motif       complement(171..209)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg61_1_0010"
                     /evalue="1.50E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg61_1"
                     /protein_end="1056"
                     /protein_start="1043"
                     /score="15.1"
                     /tool="antismash"
                     /translation="SVLKAGGTYVPLDP"
     CDS_motif       complement(735..854)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg61_1_0009"
                     /evalue="2.10E-23"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg61_1"
                     /protein_end="868"
                     /protein_start="828"
                     /score="74.8"
                     /tool="antismash"
                     /translation="RETALGAYAHQDIPFEKLVEELATERNLSFTPLFQVVFALQ"
     aSDomain        complement(891..1796)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg61_1_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="4.30E-119"
                     /label="ctg61_1_Condensation_LCL.1"
                     /locus_tag="ctg61_1"
                     /protein_end="816"
                     /protein_start="514"
                     /score="388.6"
                     /tool="antismash"
                     /translation="AVPLSFAQQRLWFLDKLEQDSSFYNLSSIVRICGAKLDAGALEKS
                     LREVTQRHEVLRTTFTIIDQQPVQVISPESQFTLPVVELGHLPPAERNAAAQRLEREET
                     ERRFDLSTGPIIRARLLRLSSEEHVLILSMHHIASDGWSTSVLIREVAALYEAYASGVE
                     SPLKELNIQYGDFAVWQREWLQGEVLDQQLAYWRKQLAGAPPVLELPTDYPRPAVKTFN
                     GAALPLRLPRSLSDALTALSRREGVTLFMSLLAAFQLLLWRYSGQDDISVGTAVANRTR
                     AETEELIGFFVNTLVLRTDVSG"
     aSModule        891..1796
                     /domains="nrpspksdomains_ctg61_1_Condensation_LCL.1"
                     /incomplete
                     /locus_tags="ctg61_1"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(903..992)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg61_1_0008"
                     /evalue="5.10E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg61_1"
                     /protein_end="812"
                     /protein_start="782"
                     /score="51.0"
                     /tool="antismash"
                     /translation="DISVGTAVANRTRAETEELIGFFVNTLVLRT"
     CDS_motif       complement(1245..1283)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg61_1_0007"
                     /evalue="6.20E-07"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg61_1"
                     /protein_end="698"
                     /protein_start="685"
                     /score="21.7"
                     /tool="antismash"
                     /translation="QYGDFAVWQREWLQ"
     CDS_motif       complement(1332..1397)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg61_1_0006"
                     /evalue="3.40E-12"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg61_1"
                     /protein_end="669"
                     /protein_start="647"
                     /score="38.7"
                     /tool="antismash"
                     /translation="MHHIASDGWSTSVLIREVAALYE"
     CDS_motif       complement(1617..1730)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg61_1_0005"
                     /evalue="7.30E-13"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg61_1"
                     /protein_end="574"
                     /protein_start="536"
                     /score="40.9"
                     /tool="antismash"
                     /translation="FYNLSSIVRICGAKLDAGALEKSLREVTQRHEVLRTTFT"
     CDS_motif       complement(1752..1784)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg61_1_0004"
                     /evalue="1.80E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="ctg61_1"
                     /protein_end="529"
                     /protein_start="518"
                     /score="10.8"
                     /tool="antismash"
                     /translation="SFAQQRLWFLDK"
     aSDomain        complement(1869..2069)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg61_1_PCP.1"
                     /evalue="4.50E-29"
                     /label="ctg61_1_PCP.1"
                     /locus_tag="ctg61_1"
                     /protein_end="490"
                     /protein_start="423"
                     /score="92.2"
                     /tool="antismash"
                     /translation="EEMLASIWSEVLGGVRVGVKDNFFDLGGHSLLATQVMSRVREAFG
                     IEIALRSLFEQPTVGELAETIGE"
     aSModule        1869..3335
                     /complete
                     /domains="nrpspksdomains_ctg61_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg61_1_PCP.1"
                     /locus_tags="ctg61_1"
                     /monomer_pairings="pro -> pro"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(2373..2438)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg61_1_0003"
                     /evalue="1.30E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg61_1"
                     /protein_end="322"
                     /protein_start="300"
                     /score="30.2"
                     /tool="antismash"
                     /translation="YAGRRDLQVKVRGFRVEVGEIEA"
     aSDomain        complement(2403..3335)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg61_1_AMP-binding.1"
                     /evalue="2.10E-72"
                     /label="ctg61_1_AMP-binding.1"
                     /locus_tag="ctg61_1"
                     /protein_end="312"
                     /protein_start="1"
                     /score="235.6"
                     /specificity="consensus: pro"
                     /tool="antismash"
                     /translation="GARVVLTQQSLAQRLPEQSPHVVRLDADWATIAQERAQNPENVAT
                     PDSAAYVIYTSGSTGLPKAVVMPHRGAVNLINYQIQSAGKPLRTLQFASLSFDVSFQEI
                     FPTLCSGGSLVLLREDVRRDAAELWRLIAEQRVQRLFLPFVALQHLAEEAGRQESVPSS
                     LRQVITAGEQLKITPQVARLFQRLDGCTLDNHYGPTETHLATAWRLEGDAGSWSRLPPI
                     GKPITNAQAYVLDDALQLVPAGVTGELYIGGAQLARGYLNRPDQTAERFIPNPFDHHGS
                     RLYRTGDLARYAANGVLGYAGRRDLQVKVRG"
     CDS_motif       complement(2523..2612)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg61_1_0002"
                     /evalue="9.80E-19"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg61_1"
                     /protein_end="272"
                     /protein_start="242"
                     /score="59.4"
                     /tool="antismash"
                     /translation="PAGVTGELYIGGAQLARGYLNRPDQTAERFI"
     CDS_motif       complement(3129..3188)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg61_1_0001"
                     /evalue="3.50E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg61_1"
                     /protein_end="70"
                     /protein_start="50"
                     /score="28.7"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGLPKAVVMPHR"
ORIGIN
        1 gtctcggccg gcggcctttg cgtgtctacg tcgaggcaga tcacgtcggt taactgcggc
       61 agtttccatt gcaactcgtg cacggcgcga agctgcgccg attgcgtgag caggcaacga
      121 atgccgagcg aggaagcgat ccagcgcagt cgttccgacg gccacgccgg atcgagcggc
      181 acataagtgc ctccggcctt gagcacgctt acgacggcca agggcatctc gagcgaacgt
      241 tccagcaaaa cgccgacgcg ctgttccggc ccgatgccga gcgccttcaa ctgatgcgcc
      301 agccggtttg cccgagtgtt caactcttca taactcagtt gctgatctgc aaagaccacc
      361 gctgtcgcct gcgggctttt cgctgcctgc gactcaaaca attcatggat gcaaagctcg
      421 cgggcgaaag gccgttgcgt gtcgttccat tcaacgagca actgcgctcg ctcgctcgcg
      481 gtcaacaaag gcaggtcggc aatcagcgcg tcgggattcg caacgatgcc ttcgagcaac
      541 gtccggaagt ggcgaagcaa ccgttgcatt gtcccggttt caaagaggtc cgtgttgtat
      601 tccagcgtgc cttcgagacc ttccgccgtc tcccacatca ccagcgaaag atcgaacttc
      661 gcgatgtccc gttcagtttc cagcagggtc agttgcaaat ctcgcaaacg gaactccgga
      721 gacggagtgt tctgcaacgc gaacacaacc tgaaacagcg gcgtgaaact caggttgcgc
      781 tcggtcgcta actcctccac caatttctca aacgggatgt cctgatgcgc atacgcaccc
      841 aacgccgtct ctctgacgcg ttggaccaac tcgcggaagg tcggatttcc gctcacgtcc
      901 gtgcgcagca ccagcgtgtt gacgaagaat ccgatcaact cttcggtctc cgcgcgcgtg
      961 cgattcgcca ccgccgtgcc gaccgaaatg tcgtcctgcc cgctgtaacg ccagagcagg
     1021 agctggaacg ccgccagcaa gctcatgaac agcgttacgc cttcgcgccg gctcaacgcc
     1081 gtcagcgcgt cgctcaacga acgcggcaac cgcagcggca gcgccgcgcc gttgaaagtc
     1141 ttcaccgcgg ggcgcggata atcggtcggc aactccagca ccggtggcgc gcccgcgagt
     1201 tgcttgcgcc agtacgcgag ttgctggtcc aacacctcgc cttgcaacca ctcgcgctgc
     1261 cagaccgcaa agtcgccata ctgaatattg agttccttga gcggcgactc cacgcccgag
     1321 gcgtaagctt cataaagtgc cgccacttca cgaatcagca cgctggtgga ccagccgtca
     1381 ctggcgatgt ggtgcatcga caagatcaaa acgtgctctt cgctcgagag acgcaacagg
     1441 cgcgcgcgga tgatcggccc ggttgacaga tcgaaacgcc gctcggtctc ttcacgctcc
     1501 agccgttgtg ccgcggcgtt tcgttccgcc ggcggcagat ggcccagctc aactacgggc
     1561 agagtgaatt gcgattccgg agagatcacc tgcaccggct gttggtcgat gatggtgaag
     1621 gtggtgcgca ggacttcgtg acgttgcgtc acttcgcgca ggcttttttc gagcgcgccg
     1681 gcgtcaagct tcgcgccgca aatacgcacg attgaagaaa ggttgtagaa cgagctgtcc
     1741 tgttcgagct tatcgagaaa ccacagtcgt tgctgcgcga aagagagcgg caccgcattg
     1801 ccttcccgct gcgctctctt aacgctctcg acctggcgcg gcattcctgc ctttgcggcg
     1861 agcagttcac cgatggtttc cgccaactct ccgacggtcg gttgctcgaa caagctccgc
     1921 aacgcaatct cgatcccgaa cgcttcccgc actcgcgaca tcacctgtgt cgccaacagt
     1981 gagtggccgc cgagatcgaa gaagttgtct ttgactccga ctcttacacc gcctaacact
     2041 tctgaccaga tcgacgccag catctcttcc acaccactgc gcggtgcgac gatggcttcg
     2101 gcgagtgcgg catgttcagc atcgggcgcc ggcaacgcgc gccgatcaac cttgccgctg
     2161 ccggtcaggg ggaacgcatc gagcagcagg aagagcgacg ggatcatgta ttcgggcagt
     2221 ttgtccttga gatgactgcg cagttcttcc ctggtcggcg acgcagatcc tcgcgccgcg
     2281 atgatgtaag cgacgaggcg ttttctgcca gcctcgtctt ctgccgccgt cacgaccgcc
     2341 tgcttcaccg agccgtgctg tttcaaaacc gcttcaatct cgccgacctc gacccgaaaa
     2401 ccgcgcacct tcacctgcag atcgcgacgg ccggcgtatc cgagcacgcc gttggccgcg
     2461 taacgggcga ggtcgccggt tcgatagagc cggctgccgt ggtgatcgaa aggattagga
     2521 atgaatctct cggccgtctg gtccgggcga ttcaagtaac cgcgcgcgag ttgcgcaccg
     2581 ccgatgtaca actcacccgt gacgccggcg gggacgagtt gcagcgcatc gtcgagcaca
     2641 tacgcctgcg cgttggtgat gggcttgccg atcggaggca acctggacca cgaaccggcg
     2701 tcgccttcga gtcgccaggc cgtggcgaga tgtgtttcag ttgggccgta gtgattgtcg
     2761 agcgtgcaac cgtcgagtcg ctgaaacagg cgcgcgacct gcggggtgat cttcaactgc
     2821 tcaccggccg tgatgacctg acgcaaactc gaaggcacgc tctcctgccg gccggcctcc
     2881 tcggccagat gttgcaaagc aacaaacggc aggaacaacc gctgcacccg ttgctcagca
     2941 atcaagcgcc acaactccgc cgcgtcgcgt cgcacatctt cgcgcaacag cacgagcgag
     3001 ccgccactgc acagtgtcgg aaagatttcc tgaaacgaca cgtcaaaact cagcgacgcg
     3061 aattgcagcg tacgcagcgg cttacccgca ctctgaattt gatagttgat caggttcacc
     3121 gcgccgcgat gaggcatcac gactgctttc ggcaagccag tcgaaccgga agtgtagatg
     3181 acgtaggcgg cactgtcggg cgtggcgaca ttctcgggat tctgcgcgcg ctcttgggcg
     3241 atggtggccc agtccgcatc gagtcgaacg acgtgcgggc tctgttccgg caggcgttgg
     3301 gcgaggcttt gctgcgtcag gaccacgcgc gcgcccgcat
//
