LOCUS       c00081_3300024..        4935 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300024186.a:Ga0247688_1001110.
ACCESSION   c00081_3300024..
VERSION     c00081_3300024..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 09:28:56
            Original ID  :: 3300024186.a:Ga0247688_1001110
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4935
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..2157)
                     /NRPS_PKS="Domain: CAL_domain (48-492). E-value: 7.8e-142.
                     Score: 465.1. Matches aSDomain:
                     nrpspksdomains_ctg81_1_CAL_domain.1"
                     /NRPS_PKS="Domain: PP-binding (604-669). E-value: 3.8e-15.
                     Score: 48.0. Matches aSDomain:
                     nrpspksdomains_ctg81_1_PP-binding.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     388.4; E-value: 6.8e-118)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg81_1"
                     /sec_met_domain="AMP-binding (E-value: 1.6e-98, bitscore:
                     317.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.2e-16, bitscore:
                     48.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTYLECLYQPDFTVSSLAELLQQRAEAAPEELAYRFLGDGEAGE
                     SRITYGELHRRARAIAARLQEMGARGERALLLYPAGLACVEAFFGCLCAGVVAVPAPPP
                     RLKRNAQRLHAMATDAAATFALTDAKLLARMESAPLPELARLRWLATDTIDESWAGAFR
                     EPELGTDSLAYLQYTSGSTSTPKGVMITHGNVLHNSAAIHRGFAHTPDSRALTWLPHFH
                     DMGLVEGIIQPLYGGFPATIMSPNSFLQHPLRWLEAVTRFQITHTGGPNFAYDLCVRRV
                     NAEQRARLDLRSWRVAYNGAEPVRVETLRHFADAFRECGFRWEAFYPGYGLAEATLKVT
                     GGNSDEPLVTCTVRADALEQHRIVAAVAEQGDTRTLVGCGQAGSDTEIEIVDAETFTPC
                     APNEIGEVWVHGPGVAAGYWGRPEETAQTFHARLAGDLASEKTYLRTGDLGFVRDGELF
                     VTGRVKDLIIIRGRNLYPHDLELAVEQCHEALRAGGGAAFALEVEGAEHLVVVQELEPR
                     RQADAAALVELIRQTLAEEFEVQPYAILLVKAGSVPKTSSGKVQRSACRLMFETGAFAA
                     LADWRRDFGVDVGQIEASQLASAEAIANWLREQLAARLRIDASAIEVDSSLTRYGVDSL
                     LAVELTHSIETQLGVLLPMSDFLSSQSITQIAARCFELFEASRSAVGSVLPAAAGGTDP
                     FPLSHGQQALWFLQQLAPESTAYNI"
     protocluster    1..4935
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:2157](-)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(1..2157)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..4935
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..4935
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     aSDomain        complement(151..345)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg81_1_PP-binding.1"
                     /evalue="3.80E-15"
                     /label="ctg81_1_PP-binding.1"
                     /locus_tag="ctg81_1"
                     /protein_end="669"
                     /protein_start="604"
                     /score="48.0"
                     /tool="antismash"
                     /translation="WLREQLAARLRIDASAIEVDSSLTRYGVDSLLAVELTHSIETQLG
                     VLLPMSDFLSSQSITQIAARC"
     aSModule        151..2013
                     /domains="nrpspksdomains_ctg81_1_CAL_domain.1"
                     /domains="nrpspksdomains_ctg81_1_PP-binding.1"
                     /incomplete
                     /locus_tags="ctg81_1"
                     /starter_module
                     /tool="antismash"
                     /type="unknown"
     aSDomain        complement(682..2013)
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg81_1_CAL_domain.1"
                     /evalue="7.80E-142"
                     /label="ctg81_1_CAL_domain.1"
                     /locus_tag="ctg81_1"
                     /protein_end="492"
                     /protein_start="48"
                     /score="465.1"
                     /specificity="Minowa: NH2"
                     /tool="antismash"
                     /translation="TYGELHRRARAIAARLQEMGARGERALLLYPAGLACVEAFFGCLC
                     AGVVAVPAPPPRLKRNAQRLHAMATDAAATFALTDAKLLARMESAPLPELARLRWLATD
                     TIDESWAGAFREPELGTDSLAYLQYTSGSTSTPKGVMITHGNVLHNSAAIHRGFAHTPD
                     SRALTWLPHFHDMGLVEGIIQPLYGGFPATIMSPNSFLQHPLRWLEAVTRFQITHTGGP
                     NFAYDLCVRRVNAEQRARLDLRSWRVAYNGAEPVRVETLRHFADAFRECGFRWEAFYPG
                     YGLAEATLKVTGGNSDEPLVTCTVRADALEQHRIVAAVAEQGDTRTLVGCGQAGSDTEI
                     EIVDAETFTPCAPNEIGEVWVHGPGVAAGYWGRPEETAQTFHARLAGDLASEKTYLRTG
                     DLGFVRDGELFVTGRVKDLIIIRGRNLYPHDLELAVEQCHEALRAG"
     CDS_motif       complement(718..780)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg81_1_0003"
                     /evalue="2.40E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg81_1"
                     /protein_end="480"
                     /protein_start="459"
                     /score="13.9"
                     /tool="antismash"
                     /translation="TGRVKDLIIIRGRNLYPHDLEL"
     CDS_motif       complement(871..954)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg81_1_0002"
                     /evalue="3.40E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg81_1"
                     /protein_end="429"
                     /protein_start="401"
                     /score="41.7"
                     /tool="antismash"
                     /translation="NEIGEVWVHGPGVAAGYWGRPEETAQTFH"
     CDS_motif       complement(1582..1641)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg81_1_0001"
                     /evalue="1.80E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg81_1"
                     /protein_end="192"
                     /protein_start="172"
                     /score="29.6"
                     /tool="antismash"
                     /translation="AYLQYTSGSTSTPKGVMITHG"
     CDS             2404..3672
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 294; E-value: 2.8e-89)"
                     /gene_kind="transport"
                     /locus_tag="ctg81_2"
                     /transl_table=11
                     /translation="MTFFKSLKVRPFALLWSGQQLSALGDSIYRVALAWWILEKTGSAK
                     AMSTIFIFASVPMLVFLLIGGVAVDRYPRARVMLLSDTFRGLLIGLVAVLAFAHRLEVW
                     HIYVVSLFFGIVGAFFGPAYRAIVPDIVARDLLPSANGLTTLSLQLADIVGPALGAMIV
                     SLSGSPTAFTLDCLSFVISALCIAPLARLALAHRSPKERKSVLHDFREGVDVVRKSSWL
                     SITIVIASLANITLSAPFAIALPFLIKRSLHGGVGSLGLVYSMLAAGSIAGTIFGTIWL
                     ERTAGLRARGLFAYSLWIAGGLFIVVFGLPVTIYAIAPAAFFVGVAFAIPELIFINTLQ
                     ELIPGKLLGRVMSIATLGAIGLVPLGSALVGWATDHVGAPTIFLLSGILTALLAALALM
                     HPVIRNLDRAAATEATDSFVQSV"
     CDS             complement(3652..4935)
                     /NRPS_PKS="Domain: nMT (1-174). E-value: 2.8e-80. Score:
                     261.1. Matches aSDomain: nrpspksdomains_ctg81_3_nMT.1"
                     /NRPS_PKS="Domain: PCP (328-396). E-value: 2.2e-30. Score:
                     96.4. Matches aSDomain: nrpspksdomains_ctg81_3_PCP.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg81_3"
                     /sec_met_domain="PP-binding (E-value: 2.8e-19, bitscore:
                     57.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="ARYVGTDFSPAALNYVRQQLATSSATNDKVVLFERRADDFQNIAP
                     NLFDCVILNSVVQYFPSVAYLLRVLEGAVNATRSGGVVFVGDVRSLPLLEAFHTSVELA
                     KADAALPLDQLRQLIRKRVGDEEELILDPAFFAALKTHLPQISHVEIMPKRARVQNELT
                     RFRYQVVIHVGEQAAPAAPLTWLDYQNVTNERTSEAARAVAMLERLAAQNGEGPTNVGE
                     FKELLSEEKGLPEQSPGPSRESSLRHKAWSEFANNPLQARFARSLVPQLRNALAEQLPD
                     YMLPSSFVVLDEWPLTPGGKIDLHALPAPDSARSPERGTLVAPRTPVEQTLAAIWSELL
                     GLERIGIHDNFFESGGHSLLATQLISRVREKFQVEIALRQLFERPTIELFARVIEEAPR
                     GSADSHIPPIVPVARQARRIQRSHRLHK"
     aSDomain        complement(3748..3951)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg81_3_PCP.1"
                     /evalue="2.20E-30"
                     /label="ctg81_3_PCP.1"
                     /locus_tag="ctg81_3"
                     /protein_end="396"
                     /protein_start="328"
                     /score="96.4"
                     /tool="antismash"
                     /translation="EQTLAAIWSELLGLERIGIHDNFFESGGHSLLATQLISRVREKFQ
                     VEIALRQLFERPTIELFARVIEEA"
     aSModule        3748..4932
                     /domains="nrpspksdomains_ctg81_3_nMT.1"
                     /domains="nrpspksdomains_ctg81_3_PCP.1"
                     /incomplete
                     /locus_tags="ctg81_3"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        complement(4414..4932)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg81_3_nMT.1"
                     /domain_subtype="nMT"
                     /evalue="2.80E-80"
                     /label="ctg81_3_nMT.1"
                     /locus_tag="ctg81_3"
                     /protein_end="174"
                     /protein_start="1"
                     /score="261.1"
                     /tool="antismash"
                     /translation="RYVGTDFSPAALNYVRQQLATSSATNDKVVLFERRADDFQNIAPN
                     LFDCVILNSVVQYFPSVAYLLRVLEGAVNATRSGGVVFVGDVRSLPLLEAFHTSVELAK
                     ADAALPLDQLRQLIRKRVGDEEELILDPAFFAALKTHLPQISHVEIMPKRARVQNELTR
                     FRYQVVIHVGE"
ORIGIN
        1 gatgttgtac gccgtgcttt ccggcgcgag ctgttgcaga aaccagagcg cctgttggcc
       61 gtgagacagc gggaacgggt cagtaccacc tgcggcagcg ggtaacaccg atccaaccgc
      121 ggagcggctc gcctcaaaaa gctcaaaaca gcgcgcggca atctgggtga tgctctggct
      181 gctgaggaag tcagacatcg gcagcagcac gccgagttgc gtctcgatgc tgtgcgtcag
      241 ctcaaccgcc agcaacgaat cgacaccgta gcgcgtgagc gagctatcaa cctcgatcgc
      301 gcttgcatca attctcaacc tcgcggccag ttgctcccgc aaccaattcg cgatcgcttc
      361 ggcgctcgcg agttgtgatg cttcgatttg cccgacatcg actccgaagt cgcgccgcca
      421 atctgccaac gctgcaaacg cacccgtctc aaacatgagg cgacaagcac tgcgttgcac
      481 cttgccgctc gatgtcttcg gcacgcttcc agctttcacc agcaggatcg cgtacggctg
      541 cacttcaaac tcttcggcca gcgtttgccg aatcaattcg acgagtgccg ccgcgtccgc
      601 ctgccgtcgt ggttccagtt cctgcaccac gaccaaatgc tctgcacctt caacttcaag
      661 cgcgaacgcc gcgccgccgc ccgctcgcaa cgcttcgtga cactgctcga cggcgagttc
      721 gagatcgtgt gggtagagat tgcggccgcg aatgatgatc agatctttga cgcggccggt
      781 gacgaacaac tcaccgtcac ggacgaaacc tagatccccc gttcgcaggt aagtcttttc
      841 agaagccaag tcgccggcga gtcgcgcgtg aaatgtttgt gctgtttcct ccggccggcc
      901 ccagtatccc gcagccacgc ctggcccatg gacccaaacc tcgccgattt cattcggcgc
      961 acatggcgtg aaagtctcgg catcgacgat ctcgatctcg gtgtcgcttc ccgcctgccc
     1021 gcaaccgacg agcgtgcgtg tgtcgccttg ctcggcaaca gccgcgacga tgcgatgttg
     1081 ttcgagcgca tccgctcgca cggtgcaggt gaccaatggt tcgtcgctgt tgccgccggt
     1141 cactttcagt gtcgcttccg cgaggccgta ccccggatag aacgcttccc aacgaaagcc
     1201 gcactcgcga aacgcatcag caaagtgtcg cagtgtctcg acgcgcaccg gctccgcgcc
     1261 gttgtaggcc acgcgccaac tgcgcaaatc cagacgcgca cgctgctctg cgttcacgcg
     1321 gcgcacgcac aggtcgtaag cgaagtttgg cccaccggtg tgcgtgattt gaaagcgcgt
     1381 gacggcttcg agccagcgca gcggatgctg gagaaaagag ttcggcgaca tgatggtggc
     1441 cgggaatccg ccgtagagcg gctggatgat cccttcaacc aaacccatgt cgtgaaagtg
     1501 cggcagccag gtgagcgcac ggctgtcagg cgtgtgcgca aagccgcgat gaatggcggc
     1561 ggagttgtgc agtacgttgc cgtgcgtgat catcacgcct ttcggcgtgg acgtcgaccc
     1621 ggaggtgtat tgcaagtagg cgaggctgtc cgtgcccaac tccggttcgc gaaatgctcc
     1681 ggcccatgat tcgtcaatcg tatcggtggc cagccaacgc aaacgcgcga gttccggcag
     1741 cggcgcggac tccatccggg cgagcaactt cgcgtcggtt aaagcaaacg tcgcggcagc
     1801 gtccgtggcc atcgcatgca gtcgttgtgc atttcgcttg agacgtggcg gaggcgcagg
     1861 aacggcgacg acgccggcgc agaggcagcc gaaaaatgct tcgacgcaag cgagtccggc
     1921 cgggtaaagg agcaatgcgc gttcgccacg cgcacccatc tcttgcagcc gcgcggcaat
     1981 cgcgcgcgca cgccggtgca gctcgccgta agtaatgcgc gactcaccgg cctcaccgtc
     2041 gccgaggaaa cgataagcca gctcttccgg cgcagcttca gcccgctgct gaagcagttc
     2101 ggccagtgaa gaaactgtga agtcgggttg ataaagacac tctaagtacg tcgtcatgtt
     2161 gcgcccagta aatcaaaatg acgaggatct cagcagagta agaagagagg tggtgggagt
     2221 tatggcacca aacctgattt cactgcgaag agatacttat ataacacatc tcactttcaa
     2281 ggtataagta acgctgtaaa tctctgtgtc tctgtgcctc tgtggttaat tcaaaatcaa
     2341 accacagaga cacagaggca cagagacaca gcattagcca ggtggttgaa caactctccg
     2401 cctatgactt ttttcaaatc gctcaaggtc cgtcctttcg cgctcctctg gtcaggacaa
     2461 caactttccg cgctcggcga cagcatttat cgcgtcgccc tggcctggtg gatcctggaa
     2521 aaaaccggct cggcgaaggc gatgagcacg attttcatct tcgcttcagt gccgatgctc
     2581 gtctttctgc tcatcggcgg cgtcgccgtc gatcgttacc cgcgcgcccg ggtgatgctt
     2641 ttgtcagaca ccttccgcgg ccttttgatc ggcctcgtcg ccgtgctcgc gtttgcgcac
     2701 cgtctggaag tctggcacat ctacgtcgtt agccttttct tcggcatcgt cggcgcgttt
     2761 ttcgggccgg cttaccgggc catcgtcccg gacatcgtgg ctcgcgattt actgccgagc
     2821 gccaacggac tgacgaccct gagcctccag ctcgccgaca tcgtcggccc ggcgctcggc
     2881 gccatgatcg tcagcctcag cggttcaccg actgctttca cgctcgactg cctttcgttc
     2941 gtcatctcgg cgctctgcat cgcgccgctc gccaggctcg cgctggccca ccgctcgccg
     3001 aaagaacgca agagcgtgct gcatgatttt cgcgaaggcg tcgacgtcgt gcgtaagtca
     3061 tcgtggcttt cgatcacgat cgtgattgct tcactcgcca acatcactct ctcggcgccg
     3121 tttgcgatcg cgcttccctt cctcattaaa cgttcgctgc acggcggcgt cggctctctc
     3181 ggcctggtct attcgatgct cgccgccgga tcgattgccg gaacgatatt cggaacgatc
     3241 tggctggaac gaacagccgg cctgcgcgca cgcggcctgt tcgcctacag cctctggata
     3301 gcgggcggac tattcatcgt cgtgttcggt ttgcccgtca ccatttacgc gattgccccg
     3361 gctgcatttt ttgtcggcgt ggctttcgcc ataccggaat taattttcat caacaccttg
     3421 caggaactga tccccggcaa gctgctcggc cgagtgatga gcattgccac gctcggcgcg
     3481 attggcctcg ttccgctcgg cagtgccctc gtcggctggg ccaccgatca cgttggcgcg
     3541 ccgaccatct tcctgctctc cggcatactc accgcgctgc tcgcagctct cgcgctgatg
     3601 catcccgtca ttcgcaatct cgaccgcgcc gccgccacgg aggccacaga ttcatttgtg
     3661 caatctgtgt gatctctgaa tccggcgtgc ttgtcgcgcc actggaacga tcggcggtat
     3721 gtggctgtcc gcgctgccgc gcggtgcttc ttcgatgacg cgcgcgaaca actcgatggt
     3781 cgggcgctca aacaattggc gcaacgcgat ctcaacctga aatttctcgc gcacgcgcga
     3841 gatgagttgc gtggccagca gcgaatggcc gcctgactcg aaaaagttgt cgtgtatgcc
     3901 gatgcgttca agaccgagca actcagacca gatcgcggcc aacgtttgct ccaccggcgt
     3961 gcgcggagcg accagcgtgc ctcgctctgg tgatctcgca ctgtcaggcg ccggcagcgc
     4021 gtgcaggtcg atcttgccgc cgggcgtgag cggccactcg tcgagcacca cgaacgacga
     4081 aggcagcatg tagtcaggca attgttcagc aagcgcgttg cgcaattgcg gaaccagcga
     4141 acgcgcaaac ctggcttgca gaggattgtt ggcaaactcg ctccacgctt tgtggcgcaa
     4201 gctgctttcg cgtgatgggc ctggtgactg ctcgggcaaa cctttctctt cactcagcaa
     4261 ttctttgaac tcgccaacgt ttgtcggacc ctcgccgttt tgggccgcca gccgttcgag
     4321 cattgcaacc gcccgcgctg cttctgacgt cctttcgttc gtaacgtttt gataatcaag
     4381 ccacgtgagt ggcgcggcag gtgcagcctg ttcgccgacg tgaatgacga cctgataacg
     4441 gaaacgcgtc agctcgtttt gcacgcgcgc ccgcttgggc atgatctcga cgtggctgat
     4501 ctgtggcaga tgcgttttga gcgccgcgaa aaaagcggga tcgagaatca gttcctcttc
     4561 gtcgcccacg cgtttgcgga tgagctgccg caactggtcc aacggcagcg cggcgtcggc
     4621 tttcgccagc tcgacagatg tgtgaaaagc ttcgagcagc ggcaagctac gcacatcgcc
     4681 gacaaagaca acgccgcctg agcgagtcgc gttgaccgcg ccttcgagca ctcgcaagag
     4741 ataagcaaca ctcggaaaat actgcacgac cgaattgaga atcacgcagt cgaacaagtt
     4801 aggcgcgatg ttttgaaagt cgtcggcacg tctttcaaac agaacgacct tgtcgttcgt
     4861 cgcgctgctg gtggccaact gctgccgcac atagttaagc gccgcgggtg agaagtctgt
     4921 gccgacgtac cgtgc
//
