LOCUS       c00122_3300024..        4179 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300024186.a:Ga0247688_1001353.
ACCESSION   c00122_3300024..
VERSION     c00122_3300024..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 09:28:56
            Original ID  :: 3300024186.a:Ga0247688_1001353
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4179
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..282)
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg122_1"
                     /sec_met_domain="Condensation (E-value: 6.3e-17, bitscore:
                     48.6, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQQQASESFRLSPQQKRVWLLQQESPAAFQVQCAIRLEGALKTEA
                     LRGAVRRLVARHGILRTTFPCVAGIKTPLQSIASDTTFAWRELDWMSCD"
     protocluster    1..4179
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:4177]"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..4177
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..4179
                     /SMILES="NC(C(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..4179
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             complement(266..4177)
                     /NRPS_PKS="Domain: AMP-binding (32-298). E-value: 7.2e-75.
                     Score: 243.8. Matches aSDomain:
                     nrpspksdomains_ctg122_2_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (407-475). E-value: 1.4e-24. Score:
                     77.9. Matches aSDomain: nrpspksdomains_ctg122_2_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (495-795). E-value:
                     6.7e-116. Score: 378.2. Matches aSDomain:
                     nrpspksdomains_ctg122_2_Condensation_LCL.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     245.5; E-value: 1.4e-74)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg122_2"
                     /sec_met_domain="Condensation (E-value: 2.5e-82, bitscore:
                     263.4, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1e-88, bitscore:
                     284.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.7e-19, bitscore:
                     56.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="QSRLPAYGGRVVCLDGEWSEIGRESEAAVASGVSGANLAYVIYTS
                     GSTGRPKGVAVTHENLVHSTTARFAYYRETVDRFLWLSSFAFDSSVAGIYWTLASGGVL
                     ILPSPGLQRDPSALIRLIEEQEVTHLLSLPSLYAAILTAKSDGELLGLRTAIVAGETCS
                     AELGKRHHEELNTAKLYNEYGPTEATVWSTAYECQSFHSGRSIPIGRAISNTKIYILDE
                     LQRETPIGVAGEIYIGGPGITRGYLNAGELTAEKFIPDQFSQSPGARLYRTADMARYLT
                     NGDIEFLGRTDNQVKLRGYRIELEEIQAVLSSHPAIAEVTITVREDVPGDQRLVAYIVG
                     LEPGKLSGRELRTYLQERLPEYMIPSAYVTLDVMPLMANGKVDRKALPLPSLNRPQDGA
                     VVLPRTLLEEVIAGIWMTVLGAGEVSVTANFFELGGHSLLATQITSRIKEAFGVELSLR
                     TLFSVPTVRGLAEVVEQELNQTPGLKAPPLKAVERAGELPLSYAQQRMWFADQLRAEGA
                     VYNVAAAVRLSGTLNRAALEETLREIIKRHEVLRTSFPAVGGRPRQVIAASVDFALGFQ
                     DLSQLAAAEREAAAQLLSLVESQAPFDLAQGPLVRASLLKLGSEEHVALFTMHHIVSDG
                     WSMGVLVREVSELYEAHSRGEEPRLAALPLQYADYAVWQREWLQGEVLAGQLRYWREQL
                     KGVPGHLRLPADRVRPEVPTYRGGHHSFAIGAERSEQLKQLSQREGATLFMTLLAAFKV
                     LLHYYSKQDDLVVGIDIANRNQLEVEGLIGFFINILIVRTNLSGNPTFRDTLRLVRDAT
                     LGAYAHQDLPFDRLVEELRPERSLSGMPLVQVMLSFQNAPQEELHLSELTLSPFEIKKS
                     TAKRDLTLFITNTKQGLAGNWNYSSELFNPTTIKRMSAHFETLLAEITAQPELRLDAAG
                     AILAAADRKQKASEKDERRNSRLKQFMNVAPRAIRVSQVPLIKTSFLSATERIPLVVEP
                     AFDDVDLPAWASSQTNFLEATLSDHGAILFRGFNAVSPHDLEQFALSVCPELFGEYGDL
                     PREGISGKVYGSTPYPPEQAILFHNESSHLRRWPMKIWFFCMRPATQGGETPVVDCRRV
                     YESLRPEIRERFARKKIMYVRNYVEGLDVSWQQFFRTSDKAIVEEYCRKNSVAWEWTPG
                     NGLRTRQVCDAVQQHPTTGQTVFFNQLQAHHLSCLEPATRSSLLSLLKEEDLPRNAYYG
                     DGSRIEDSVVDEIREVYQANAISFLWQKGDILMLDNMLTAHGRNPYRGERKIVVAMGEM
                     MSNQQVDAREMRQVNATAS"
     CDS_motif       complement(1634..1753)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg122_2_0009"
                     /evalue="3.50E-23"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg122_2"
                     /protein_end="848"
                     /protein_start="808"
                     /score="74.1"
                     /tool="antismash"
                     /translation="RDATLGAYAHQDLPFDRLVEELRPERSLSGMPLVQVMLSFQ"
     aSDomain        complement(1793..2692)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg122_2_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="6.70E-116"
                     /label="ctg122_2_Condensation_LCL.1"
                     /locus_tag="ctg122_2"
                     /protein_end="795"
                     /protein_start="495"
                     /score="378.2"
                     /tool="antismash"
                     /translation="ELPLSYAQQRMWFADQLRAEGAVYNVAAAVRLSGTLNRAALEETL
                     REIIKRHEVLRTSFPAVGGRPRQVIAASVDFALGFQDLSQLAAAEREAAAQLLSLVESQ
                     APFDLAQGPLVRASLLKLGSEEHVALFTMHHIVSDGWSMGVLVREVSELYEAHSRGEEP
                     RLAALPLQYADYAVWQREWLQGEVLAGQLRYWREQLKGVPGHLRLPADRVRPEVPTYRG
                     GHHSFAIGAERSEQLKQLSQREGATLFMTLLAAFKVLLHYYSKQDDLVVGIDIANRNQL
                     EVEGLIGFFINILIVRTNLS"
     aSModule        1793..2692
                     /domains="nrpspksdomains_ctg122_2_Condensation_LCL.1"
                     /incomplete
                     /locus_tags="ctg122_2"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(1802..1891)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg122_2_0008"
                     /evalue="5.30E-11"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg122_2"
                     /protein_end="792"
                     /protein_start="762"
                     /score="34.9"
                     /tool="antismash"
                     /translation="DLVVGIDIANRNQLEVEGLIGFFINILIVRT"
     CDS_motif       complement(2144..2182)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg122_2_0007"
                     /evalue="8.50E-07"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg122_2"
                     /protein_end="678"
                     /protein_start="665"
                     /score="21.3"
                     /tool="antismash"
                     /translation="QYADYAVWQREWLQ"
     CDS_motif       complement(2231..2296)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg122_2_0006"
                     /evalue="2.50E-13"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg122_2"
                     /protein_end="649"
                     /protein_start="627"
                     /score="42.3"
                     /tool="antismash"
                     /translation="MHHIVSDGWSMGVLVREVSELYE"
     CDS_motif       complement(2513..2629)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg122_2_0005"
                     /evalue="1.60E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg122_2"
                     /protein_end="555"
                     /protein_start="516"
                     /score="55.8"
                     /tool="antismash"
                     /translation="AVYNVAAAVRLSGTLNRAALEETLREIIKRHEVLRTSFPA"
     CDS_motif       complement(2651..2680)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg122_2_0004"
                     /evalue="3.60E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="ctg122_2"
                     /protein_end="509"
                     /protein_start="499"
                     /score="9.9"
                     /tool="antismash"
                     /translation="SYAQQRMWFAD"
     aSDomain        complement(2753..2956)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg122_2_PCP.1"
                     /evalue="1.40E-24"
                     /label="ctg122_2_PCP.1"
                     /locus_tag="ctg122_2"
                     /protein_end="475"
                     /protein_start="407"
                     /score="77.9"
                     /tool="antismash"
                     /translation="EEVIAGIWMTVLGAGEVSVTANFFELGGHSLLATQITSRIKEAFG
                     VELSLRTLFSVPTVRGLAEVVEQE"
     aSModule        2753..4081
                     /complete
                     /domains="nrpspksdomains_ctg122_2_AMP-binding.1"
                     /domains="nrpspksdomains_ctg122_2_PCP.1"
                     /locus_tags="ctg122_2"
                     /monomer_pairings="val -> val"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(3254..3319)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg122_2_0003"
                     /evalue="2.20E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg122_2"
                     /protein_end="308"
                     /protein_start="286"
                     /score="32.6"
                     /tool="antismash"
                     /translation="FLGRTDNQVKLRGYRIELEEIQA"
     aSDomain        complement(3284..4081)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg122_2_AMP-binding.1"
                     /evalue="7.20E-75"
                     /label="ctg122_2_AMP-binding.1"
                     /locus_tag="ctg122_2"
                     /protein_end="298"
                     /protein_start="32"
                     /score="243.8"
                     /specificity="consensus: val"
                     /tool="antismash"
                     /translation="VSGANLAYVIYTSGSTGRPKGVAVTHENLVHSTTARFAYYRETVD
                     RFLWLSSFAFDSSVAGIYWTLASGGVLILPSPGLQRDPSALIRLIEEQEVTHLLSLPSL
                     YAAILTAKSDGELLGLRTAIVAGETCSAELGKRHHEELNTAKLYNEYGPTEATVWSTAY
                     ECQSFHSGRSIPIGRAISNTKIYILDELQRETPIGVAGEIYIGGPGITRGYLNAGELTA
                     EKFIPDQFSQSPGARLYRTADMARYLTNGDIEFLGRTDNQVKLRG"
     CDS_motif       complement(3407..3496)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg122_2_0002"
                     /evalue="2.00E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg122_2"
                     /protein_end="257"
                     /protein_start="227"
                     /score="48.9"
                     /tool="antismash"
                     /translation="PIGVAGEIYIGGPGITRGYLNAGELTAEKFI"
     CDS_motif       complement(4004..4063)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg122_2_0001"
                     /evalue="7.20E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg122_2"
                     /protein_end="58"
                     /protein_start="38"
                     /score="33.8"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVAVTHE"
ORIGIN
        1 gtcacaactc atccaatcaa gctcgcgcca cgcaaaggta gtatcgctcg cgatagattg
       61 gaggggagtt ttgatcccag ccacgcaagg aaaagtcgta cgcaggattc cgtgccgcgc
      121 aaccagtctg cgcacagctc ctcttaacgc ttccgttttc aacgctcctt cgagtcgaat
      181 cgcacactgc acttgaaaag cagcagggct ctcctgttgt aatagccaca ctcgcttttg
      241 ttgaggagag agccggaaag attcactagc ttgctgttgc atttacttgc ctcatttcgc
      301 gtgcgtcaac ctgctggtta ctcatcatct cgcccatcgc caccacaatc tttcgttcgc
      361 cgcgatacgg attgcgaccg tgagccgtga gcatattgtc gagcattaat atgtctccct
      421 tctgccagag aaagctgatg gcgttcgctt gatagacctc gcgaatctcg tctaccactg
      481 agtcttcgat tcgcgagcca tcaccgtagt aagcgttccg cggtaaatct tcttccttta
      541 acagagatag cagtgacgac cgtgtcgccg gttccaggca tgagagatga tgagcctgaa
      601 gttgattgaa aaatacggtc tggcctgttg tcggatgctg ttgtactgcg tcgcatacct
      661 gccgcgttct taaaccgttg ccaggtgtcc attcccaggc caccgaattc ttacggcagt
      721 attcctccac tattgccttg tcgctggtac gaaagaactg ttgccagctc acgtccagtc
      781 cttccacgta gtttcggaca tacattattt tcttgcgcgc aaatcgctct cggatttccg
      841 gtcgaaggga ttcatatact ctgcggcaat caacaaccgg cgtctcgccg ccctgagttg
      901 ccggccgcat gcagaagaac cagattttca tgggccagcg tcgcaggtga gagctttcgt
      961 tatgaaacag aatggcctgt tctggcggat agggcgttga gccgtagact ttcccgctta
     1021 tgccttcgcg tggcaagtca ccgtattctc caaacagctc tggacacaca ctcagcgcaa
     1081 actgctcgag gtcatgcggc gatacggcat tgaatccacg gaacaggatg gcgccgtgat
     1141 ccgacaatgt tgcttcgagg aaatttgttt ggctactggc ccacgcaggc agatcaacat
     1201 catcaaaggc aggttccacc actaacggaa ttctttcagt tgcactcaga aaactcgtct
     1261 tgattaaggg cacttgcgat accctgatgg ctcgcggcgc aacgttcatg aactgtttca
     1321 accgactatt tctccgctcg tctttctcgc ttgctttttg tttcctgtct gccgcagcca
     1381 aaatcgcgcc ggctgcatcc agtcgcagct cgggttgcgc tgtgatctca gccagcagcg
     1441 tctcaaagtg cgcggacatc cgtttgatgg tggtgggatt gaagagctcg ctactgtagt
     1501 tccagttgcc ggcgagccct tgtttggtat tcgtaatgaa caaggtcaaa tcgcgtttgg
     1561 ctgtgctctt tttgatctcg aatggactga gtgtcagctc ggataagtgc agttcttctt
     1621 gcggcgcgtt ttgaaatgag agcattacct gaacgagagg catcccgctc aaggatcttt
     1681 ctggccgtaa ttcttcgacc aatcgatcga atggtagatc ctgatgcgcg tatgctccca
     1741 acgtcgcgtc tcgcaccagg cgcagtgtgt cccgaaaagt tggattgcca gagaggttgg
     1801 tccgaacaat caggatattg ataaagaacc ctatcagtcc ttcaacctca agctgattcc
     1861 ggttagcgat atcaattccc actaccagat cgtcttgttt cgagtagtaa tgcaacagca
     1921 ctttgaaagc cgccagcagg gtcatgaaca gagtcgcacc ttcacgctgg ctcaactgct
     1981 tcaactgctc gctccgctcc gctccgatgg caaacgagtg atgtccgcca cggtaggtcg
     2041 gcacctccgg ccgcacccgg tccgccggta atcttaagtg ccctggcact ccctttaact
     2101 gctcccgcca gtaccgcaac tggcccgcca atacttctcc ttgcagccac tcccgctgcc
     2161 atactgcata atctgcgtat tgcaacggca acgccgccaa ccttggctct tccccgcgac
     2221 tgtgcgcttc gtacagctca ctcacttctc gcaccaacac tcccatcgac cacccgtcac
     2281 tcacgatgtg gtgcatggtg aacaaggcca cgtgctcttc gctccccagt ttcaacaaac
     2341 tcgcccgcac caatggtccc tgcgccaggt cgaacggcgc ttgcgactcg accagcgaca
     2401 acagctgcgc ggccgcttcc cgctccgccg ccgctaactg actcaggtct tgaaacccaa
     2461 gggcaaagtc gacgctcgcc gcgatcacct gccgcggtct accacccact gccggaaagc
     2521 tcgtgcgcaa cacttcatgg cgcttgatga tctcgcgcag cgtttcttcc agcgccgctc
     2581 ggttcaacgt cccgctcaga cgcactgccg cggccacgtt gtagaccgcg ccttcagctc
     2641 gtagctgatc ggcgaaccac atgcgctgtt gcgcatagga caacggcaac tcacctgccc
     2701 gttctactgc cttcagtggc ggcgccttca ggccaggtgt ctgattcagt tcctgctcga
     2761 ctacttctgc caacccacga actgttggaa cactaaacaa agtacgaagc gacaactcaa
     2821 ccccgaacgc ttctttgata cgcgaagtta tttgagtcgc cagcagtgaa tgcccgccta
     2881 gctcgaagaa gtttgcagtg acactcactt cgccggctcc tagcaccgtc atccagatac
     2941 ctgcgattac ttcttcgagc agcgtccgag gcaatacgac tgcgccatcc tgtggtctat
     3001 tcagtgaagg cagtggcagt gctttacgat ctactttacc gttagccatc aacggcatta
     3061 catcaagcgt tacgtaagct gacgggatca tgtattccgg taaacgctct tgcagatacg
     3121 tgcgcaattc cctgcctgat aacttgccgg gctctaaccc cacgatgtag gcaaccaatc
     3181 gttgatcccc ggggacgtct tcgcgcactg tgatcgtaac ttcagcaatc gcgggatggg
     3241 agctaagcac cgcttgaatc tcttcgagtt ctatgcgata gcccctcagc ttcacctgat
     3301 tgtctgttcg cccgaggaac tcgatatcgc cgttcgtcag gtaccgggcc atatctgcgg
     3361 ttcgatagag tcgtgctccc ggcgattgac tgaactgatc agggataaac ttctcggccg
     3421 tcagctcacc ggcattcaga tatccgcgcg tgatgcctgg gccaccgata tatatttcac
     3481 ctgcaacccc gatgggtgtt tcccgttgca gttcgtcaag gatgtagatc tttgtattgc
     3541 tgattgcccg cccaatagga attgagcgcc ctgagtgaaa cgattggcat tcataagccg
     3601 tgctccagac ggtggcttca gttggaccat actcgttgta caactttgct gtgttcaact
     3661 cctcgtggtg ccgtttgcct aactccgcgc tgcacgtctc gccggcgaca atagcggttc
     3721 tcaaccccag cagctcgccg tcgcttttcg cggtcaagat ggcagcatat aaagacggca
     3781 gactcagcag gtgcgtcacc tcttgctctt cgatcaggcg gatcagtgcg ctcgggtcgc
     3841 gctggagtcc tggcgacggc agtatcagta caccgccact tgccagcgtc cagtagatgc
     3901 cggccacaga gctgtcgaac gcgaacgagg agagccacag aaaccgatca accgtttcgc
     3961 ggtaataagc gaaacgtgcg gtggtcgaat ggaccagatt ttcgtgagtg accgccactc
     4021 ctttcggccg ccccgtcgaa cccgacgtgt agatcacata ggccaggttc gccccgctca
     4081 ccccgctcgc gacagccgcc tcactctccc gcccgatctc actccattcc ccatccagac
     4141 acaccactcg cccaccgtag gccggcaacc gcgactgca
//
