LOCUS       c00205_3300024..        4543 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300024186.a:Ga0247688_1001222.
ACCESSION   c00205_3300024..
VERSION     c00205_3300024..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 09:28:56
            Original ID  :: 3300024186.a:Ga0247688_1001222
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4543
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4543
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:2474](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(3..2474)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..4543
                     /SMILES="NC(CC(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..4543
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     aSDomain        complement(3..125)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg205_1_PCP.1"
                     /evalue="1.10E-16"
                     /label="ctg205_1_PCP.1"
                     /locus_tag="ctg205_1"
                     /protein_end="824"
                     /protein_start="783"
                     /score="52.6"
                     /tool="antismash"
                     /translation="EEVLAGIWSQVLGVDAVGIHENFFESGGHSLLATQAISQIR"
     aSModule        3..1646
                     /complete
                     /domains="nrpspksdomains_ctg205_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg205_1_PCP.1"
                     /locus_tags="ctg205_1"
                     /monomer_pairings="leu -> leu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS             complement(3..2474)
                     /NRPS_PKS="Domain: AMP-binding (276-671). E-value:
                     8.8e-103. Score: 335.7. Matches aSDomain:
                     nrpspksdomains_ctg205_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (783-824). E-value: 1.1e-16. Score:
                     52.6. Matches aSDomain: nrpspksdomains_ctg205_1_PCP.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     110.1; E-value: 2.5e-33)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg205_1"
                     /sec_met_domain="Condensation (E-value: 5.7e-16, bitscore:
                     45.5, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-117, bitscore:
                     380.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2e-09, bitscore:
                     25.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERVIDEKAPGLVIFDRKTKGQQEYWVKQLSRAIEPSNIALDYPR
                     PRTYSGETETVEFELTPEVYRRLIDLVRDGDFLLYTTLLAALKVCLHKYTGNRTIVVGS
                     PSRKQDNAAPHAGNALAIVAEVHPQLPFKQLLINMRQTLLDAYSNQHYPFERLVRDLEL
                     EDIDNKCPLFDVELALANIHLPTANLKTDINITFIRHADRITGRIEFNQSLFQLKSIEV
                     FLKHYLNVLSSALENTSAPIADLHLLSSAERQQLLFDWNDTRTEYERDACIHELFAAQA
                     EKNPQAIAVSTPAGAITYQELNLRANKLARYLKTLGVGPEVLVAICAERGSEIILAMLG
                     ILKAGGAFVPLDPDYPKDRVAFMLADSNAPVLITMRELADDLPEHNAHTVYLDADWQAI
                     EQHSDENLPVETSTHNLAYMIYTSGSTGWPKGVQVQHRGLVNLVTWHQRFYGVTPADRA
                     SQLATPAFDAYVWEVWPYLTAGASVHVPDRETGLSVPKLLQWLAGERITFSFLVTALAE
                     VAIETEWPDGLCLKAVLTGGDKLHAAPRQPLVGNLFNHYGPTEATVVATWGPVAETQTD
                     VAPSIGRPLPNTQAYLLSDDLQPVPAGARGELFIGGDGLARGYLNHPDLTAASFIPNPF
                     SSEPGARLYRSGDFARYLPDGSIDFIGRDDHQVKIRGFRIELGEIEIALEEHPAVRQAI
                     VMGRDDPRGERRLAAYVVQEESHDGVVAQSELRNFLAERLPSYMVPSAFVQLERLPLTA
                     NGKVDRRALPAPDWVSQEARAAFVSPRNAIEEVLAGIWSQVLGVDAVGIHENFFESGGH
                     SLLATQAISQIR"
     CDS_motif       complement(432..497)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg205_1_0005"
                     /evalue="3.60E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg205_1"
                     /protein_end="681"
                     /protein_start="659"
                     /score="38.2"
                     /tool="antismash"
                     /translation="FIGRDDHQVKIRGFRIELGEIEI"
     aSDomain        complement(462..1646)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg205_1_AMP-binding.1"
                     /evalue="8.80E-103"
                     /label="ctg205_1_AMP-binding.1"
                     /locus_tag="ctg205_1"
                     /protein_end="671"
                     /protein_start="276"
                     /score="335.7"
                     /specificity="consensus: leu"
                     /tool="antismash"
                     /translation="FAAQAEKNPQAIAVSTPAGAITYQELNLRANKLARYLKTLGVGPE
                     VLVAICAERGSEIILAMLGILKAGGAFVPLDPDYPKDRVAFMLADSNAPVLITMRELAD
                     DLPEHNAHTVYLDADWQAIEQHSDENLPVETSTHNLAYMIYTSGSTGWPKGVQVQHRGL
                     VNLVTWHQRFYGVTPADRASQLATPAFDAYVWEVWPYLTAGASVHVPDRETGLSVPKLL
                     QWLAGERITFSFLVTALAEVAIETEWPDGLCLKAVLTGGDKLHAAPRQPLVGNLFNHYG
                     PTEATVVATWGPVAETQTDVAPSIGRPLPNTQAYLLSDDLQPVPAGARGELFIGGDGLA
                     RGYLNHPDLTAASFIPNPFSSEPGARLYRSGDFARYLPDGSIDFIGRDDHQVKIRG"
     CDS_motif       complement(585..674)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg205_1_0004"
                     /evalue="4.50E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg205_1"
                     /protein_end="630"
                     /protein_start="600"
                     /score="50.9"
                     /tool="antismash"
                     /translation="PAGARGELFIGGDGLARGYLNHPDLTAASFI"
     CDS_motif       complement(1167..1226)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg205_1_0003"
                     /evalue="4.60E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg205_1"
                     /protein_end="436"
                     /protein_start="416"
                     /score="28.3"
                     /tool="antismash"
                     /translation="AYMIYTSGSTGWPKGVQVQHR"
     CDS_motif       complement(1419..1460)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg205_1_0002"
                     /evalue="7.70E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg205_1"
                     /protein_end="352"
                     /protein_start="338"
                     /score="19.0"
                     /tool="antismash"
                     /translation="LGILKAGGAFVPLDP"
     CDS_motif       complement(1983..2057)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg205_1_0001"
                     /evalue="6.30E-11"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg205_1"
                     /protein_end="164"
                     /protein_start="139"
                     /score="34.6"
                     /tool="antismash"
                     /translation="RQTLLDAYSNQHYPFERLVRDLELED"
     CDS             complement(2502..4541)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="other (smcogs) SMCOG1277:Radical SAM
                     domain protein (Score: 282.3; E-value: 1.1e-85)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg205_2"
                     /sec_met_domain="PF04055 (E-value: 5.1e-26, bitscore: 79.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VTTTLYVSPYPILEIISFIREHNKTAQILVGGPFIHGQIKDHDEL
                     SLQRLFKMIGADIYVISQEGEAALVNIIRTLKNRGNLDNVNNIAYRSGEKYIRTAESIE
                     SNPLEENMVDYALFPSNEIGEFVSLRTAKSCPFSCAFCGFPQRAGKYKYESVELVEGEL
                     NRLRDIGTVTTLTFLDDTFNVPKERFKEILRMMIRNQYGFKWNSFYRSDHGDEEAIELM
                     GKAGCEGVFLGVESGSDEMLLRMNKTARQKHYLKAIPLLRAAGVSTHANVIVGFPGETY
                     DTVQETVDFIETAKPDFFRAQLWYADPVTPIWEKRDQYGVKGTAFNWSHNTMDFETACD
                     LIDKMFVSIENSIWLPQNGFEQWSTFYLQRKGMTVEQIKTFLKCFNAVIKEKLTYPSKQ
                     EIDPKLFASLKQSCEFDRSARPDMSPVEIFNGYETARKYWLSEFGGDVPASHIELLADH
                     EGTAAEERTTTSFPVSSLVSNGLTLRPEEDWPTFILAAFGALLLRLNGQEDITVVSSLA
                     DEAAPPIPLRLKPLWSSTFAEFLQSVRQKTVQGAAQRTYALHILTNPLRLAEYGCKPPI
                     LDLGFTYREAGRKHEAGLHPEVDQKLKLVLNVTRDGDELSFAFSCMKSWFKEETIVRLG
                     SYLDSIFKEVAINPTVMMGEIVLDSGERESDSAIEQDANEAFNF"
ORIGIN
        1 tcgcggatct gcgagatcgc ctgcgtcgcg agcagtgagt ggccgccact ctcgaagaag
       61 ttctcgtgaa tcccgactgc atccacgccc agcacctgtg accaaatgcc cgctaacact
      121 tcttcgatcg cattgcgcgg cgagacaaac gccgcccgcg cttcctggct cacccagtcc
      181 ggcgccggca acgcgcgccg gtctaccttc ccgttagccg ttaacggcaa tcgttctaac
      241 tgcacgaagg ccgacggcac catgtacgac ggcaatctct ccgccagaaa gtttcgcaac
      301 tcactctgcg ctaccactcc atcatgcgac tcttcctgca ccacataagc tgcgagccgg
      361 cgttcaccgc gcggatcgtc acggcccatc acgatcgcct ggcgaacggc gggatgttct
      421 tccagggcaa tctcgatctc gcccagttcg atacgaaaac ctcgaatctt cacctggtga
      481 tcgtcacggc cgatgaagtc aatcgagccg tcaggcaggt aacgagcaaa atcgcctgag
      541 cgataaagcc tggcacctgg ctccgagctg aatggattgg gaataaaact cgccgccgtc
      601 aggtcgggat gattcaaata gcctcgcgcg agcccgtcac cgccgatgaa taattcgccg
      661 cgcgcgcctg cgggaaccgg ctgcagatcg tcagacaaca aatacgcctg cgtgttaggc
      721 agcggtcgcc caatcgaggg cgccacgtcc gtttgagttt cagccaccgg cccccacgtc
      781 gcgacgacgg tggcttcagt tgggccatag tggttgaata aattgccaac gagcggctgc
      841 cgtggcgccg catggagttt gtcgccacca gtaagcacag ctttcaaaca caggccgtcg
      901 ggccattccg tttcaatcgc gacttccgcg agggcagtta cgagaaagct gaaggtgatc
      961 cgttcgccgg ccagccactg caacaacttc ggaacgctca ggccggtttc tcgatcgggc
     1021 acgtgcacgc tggctccggc ggtcaggtac ggccacactt cccacacgta ggcgtcgaat
     1081 gccggtgtcg ctaactgcga agcacgatct gccggcgtga cgccgtaaaa ccgctggtgc
     1141 caggtaacaa gattcaccag cccgcgatgc tgcacctgta cgcccttggg ccaaccagtg
     1201 gatcccgacg tgtagatcat gtaagcgaga ttatgagttg acgtttcgac cggaaggttc
     1261 tcgtcgctgt gctgttcgat ggcttgccaa tcggcatcga gataaaccgt gtgcgcgttg
     1321 tgctcgggca gatcatcggc gagttcacgc atcgtgatca gcaccggcgc gtttgaatcc
     1381 gccaacatga acgcgacccg atcctttgga tagtccggat cgagaggcac gaacgcaccg
     1441 ccggccttga gaatgcccag catcgccaga atgatctcgg aaccgcgttc ggcgcagatt
     1501 gctaccagca cctctggccc aacacccaga gtcttcaggt aacgggccag cttgttcgcg
     1561 cggagattca actcttgata ggtgatcgcg ccggccggag ttgagactgc aatggcttgc
     1621 ggatttttct cggcctgcgc tgcaaatagc tcgtgaatgc acgcatcccg ctcgtactcc
     1681 gtccgcgtgt cgttccaatc aaacagaagt tgttgtcgct ccgcggaact caggaggtga
     1741 agatcggcga tgggcgcact ggtattttcc aacgcgctgc tcaacacgtt gaggtagtgt
     1801 ttgagaaaga cctcgatgct cttcagttgg aaaaggcttt gattgaattc aatccggccg
     1861 gttatgcgat cggcgtgtcg aatgaacgtg atgtttatgt cggtcttgag attggccgtg
     1921 ggaaggtgaa tgttagccag cgccaactcg acgtcaaaca acgggcattt gttatctata
     1981 tcctccaact ccagatctct taccagccgt tcaaacggat aatgctgatt ggaataagca
     2041 tccagcagag tctggcgcat attaataagg agctgtttga acggcagttg aggatgaact
     2101 tcagcgacga tcgcgagcgc gttgccggca tgaggcgccg cattgtcctg cttgcggctc
     2161 gggctgccca cgacgatggt cctgttgccc gtgtacttgt gcaggcaaac tttcagcgcc
     2221 gccagcaacg tcgtgtaaag cagaaaatcg ccgtcgcgga caagatcgat caagcggcga
     2281 tagacctcgg gcgtcaactc gaattcaaca gtctcagtct caccgctgta agtcctgggc
     2341 cggggataat cgagggcgat gtttgacggc tcgattgccc gggacaactg tttgacccag
     2401 tactcctgct gccctttcgt cttacggtcg aagattacga ggcccggcgc tttttcgtcg
     2461 attacccgtt ccatttgacc ttaccttttc gaagattgtg atcagaaatt gaaggcttcg
     2521 tttgcgtcct gctcgatcgc tgaatcggat tcccgttcac cactatccaa cacaatctcg
     2581 cccatcatca cggtcgggtt tatggcgacc tctttgaaga tggaatccag ataagagccg
     2641 agccggacga ttgtttcttc cttgaaccag ctcttcatgc aggagaaggc gaagctcaac
     2701 tcgtcaccgt cgcgggttac gttgaggacc agtttcaact tctgatcgac ttccggatgg
     2761 agacctgctt catgcttgcg gccggcttcg cgataggtga atcccaaatc caaaatcggc
     2821 ggcttgcagc cgtactccgc gaggcgcaaa ggattcgtga gaatgtgaag tgcgtaggtg
     2881 cgttgggccg ccccttgaac agtcttttgc cgcacgctct gcaggaactc agcgaaggtt
     2941 gaactccaca aaggcttgag acgaagcgga atcggcggtg ctgcttcgtc agccaaactg
     3001 ctgacgactg tgatgtcctc ctgcccattt agtcgcagga gcaacgcgcc gaacgccgct
     3061 aggataaagg tgggccagtc ttcttccggc ctcagggtca acccattact aacgaggctg
     3121 gaaacaggga aagaagtcgt ggttcgttct tctgctgctg ttccttcatg atctgccagc
     3181 agctcaatat gggaagccgg tacatcacca ccaaattcac tgagccagta ctttcgcgcc
     3241 gtctcatagc cgttgaagat ctcaaccggc gacatgtcgg gacgtgcgga tcgatcgaac
     3301 tcgcaactct gtttcaggct cgcgaacagt ttcggatcga tctcttgctt gctcgggtag
     3361 gtcagcttct ccttgatcac ggcgttgaaa catttcagga acgtcttgat ctgctcaacc
     3421 gtcattccct ttctttgcag gtaaaaagtg ctccactgtt caaaaccatt ctgcggcagc
     3481 cagatcgagt tctcgatgga gacaaacatt ttgtcgatca ggtcgcaggc ggtttcgaag
     3541 tccatcgtgt tgtgcgacca gttgaaagcg gttcctttca ctccatactg atcgcgcttt
     3601 tcccagatgg gagtgaccgg atcggcatac cacagttgcg ctctaaagaa atcgggcttt
     3661 gccgtttcga tgaaatcaac tgtctcctgc acggtgtcgt acgtctctcc aggaaaacca
     3721 acgatcacgt ttgcatgggt tgagacaccg gccgccctca acaacgggat ggcctttaaa
     3781 tagtgttttt gcctggccgt cttgttcatt cgcagcagca tctcgtcact gcctgactcg
     3841 accccgagaa acacgccctc acatcctgct ttccccatca actcaatggc ttcttcatcg
     3901 ccatgatcag agcggtaaaa tgagttccac ttgaaaccgt actggtttct gatcatcatc
     3961 cgcaggatct ctttgaatcg ttctttcggc acgttgaagg tatcgtcgag gaaagtcagc
     4021 gtggtgacgg tgccgatatc gcgcagtcga ttcaactcgc cttcgaccag ctcaaccgac
     4081 tcatacttgt atttgccggc gcgttgcggg aaaccacaga acgcacacga gaaaggacac
     4141 gacttcgcgg tgcggaggga aacaaactcg ccaatctcat tactcgggaa gagagcgtaa
     4201 tccaccatgt tctcttccag cgggtttgac tcgatcgact cggcggtgcg gatgtatttt
     4261 tcgccgctgc gataagcaat gttattgacg ttatcgaggt tgccgcgatt cttcagcgta
     4321 cgaatgatat tgacgagagc ggcttctccc tcctggctga tgacataaat gtccgcccca
     4381 atcattttga acagccgttg cagagatagt tcgtcgtgat ccttgatctg gccgtgaatg
     4441 aaaggcccgc cgacaaggat ctgcgcggtc ttgttatgct cacgaatgaa ggagatgatc
     4501 tcgaggatcg ggtaaggcga aacgtataac gtggtggtga cgg
//
