LOCUS       c00228_3300024..       11842 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300024186.a:Ga0247688_1000045.
ACCESSION   c00228_3300024..
VERSION     c00228_3300024..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 09:28:56
            Original ID  :: 3300024186.a:Ga0247688_1000045
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 46978
            Orig. end    :: 58820
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11842
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[51978:53820](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or
                     TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or
                     TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692
                     or TIGR01193)"
                     /neighbourhood="5000"
                     /product="bacteriocin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..6842
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or
                     TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or
                     TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692
                     or TIGR01193)"
                     /neighbourhood="5000"
                     /product="bacteriocin"
                     /protocluster_number="1"
     cand_cluster    1..11842
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or
                     TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or
                     TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692
                     or TIGR01193)"
                     /kind="single"
                     /product="bacteriocin"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11842
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="bacteriocin"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or
                     TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or
                     TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or
                     TIGR01193)"
                     /tool="antismash"
     CDS             786..1979
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_tran_28_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg228_47"
                     /sec_met_domain="Glyco_tran_28_C (E-value: 4.4e-08,
                     bitscore: 25.2, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDQPRIPKILIISSDTGGGHRSAAAAIVAGVQKFLDSESYAIRV
                     VRAVEESHHLADKLVRLYNWILRNRQHWMKYYYWFINRIRPDTREFFHKRCVGYVRGLF
                     ERWCPHIVVSVHPLTQHIFGRVLKDLNLADRVPLVSVVTDPCYGFWKGWACDAVTLYLV
                     ASEEAQRQLIDYGVAPERIKISGMPVHPKFAYPGEEAAQAARRALGLDPEKFTVFVNAG
                     WIGGGNIPQIFRELVRGELDVQAIFLAGKNEDLRAVAETIARDAPFPIKVIGYSDEIEQ
                     LMSAANVMISKLGGLTTFEALACRVPIIADVITDPMPQEAGTARLIAQRGAGVMLKHSS
                     DVVAVVRRMVEDEVHYSRMRAATVGLAIPNATRHIVEEIAALIPPSEKAVLNEVVSA"
     CDS             2017..3696
                     /locus_tag="ctg228_48"
                     /transl_table=11
                     /translation="MDKEPWVLGISASHNGSVCLLHGDEIVVAIQEERLSRVKRHRIYG
                     KGPSLATSYCLSYAGIEPAELDLIVLCVQGRLSDEVNDIRLEPLLNIQAHRTPVVAIPH
                     HYGHAFSAFATSGFEESAILVVDGTGSPATDFTAAEKSILNGHAENGWETISLYYGSGT
                     DITPLEKHVVDRGAWLLMHDGEMPAFGSLGGMFSAAAEQIFGEVTEAGKVMGLAGYGKP
                     EFPARDFFEIENGRFHFKDKVPQQFRHNVRWPEAAPEYETLAASVQGALEDALLYLVRH
                     LRELCPSRNLCYAGGVALNSVANERLIRESGYDQIYIMPAAEDSGAAVGAAYYGLWQLT
                     GCNLRRRLPHDALGRSYSATEVTDVLERVSEVRSVRSTDVIRDAVELLCDGKIIGWFDG
                     GSELGPRALGQRSILCDPRSPDAKATLNRRVKMREAFRPFAPAVLLEAAPQWFEFGGSA
                     PESPFMLRVCEVKQEKKDEVPAIVHVDATGRLQTLTREANGRFYELVKQFYERTGVPML
                     LNTSFNRMGEPIVETPADAIGCLLRTDLDCCVFADRIVWKNG"
     CDS             3689..4294
                     /locus_tag="ctg228_49"
                     /transl_table=11
                     /translation="MAELSASHFNLYLAPHFFDAGECARLLAALRPSPTTQAPVYIEGS
                     DRFVHEDVRRTTSLHPADEIFSVVHSRLFEEKPALEKHFGLTLTDCERPQFLRYQTGDF
                     FVRHQDGNTEQLQFDHLRIRRISLIVFLNEHTGQPQADSFSGGSLNFYDLNEAGPDGPT
                     AFPLFGETGLLVAFTAETMHEVAPVTNGERFTVISWFR"
     CDS             4317..4877
                     /locus_tag="ctg228_50"
                     /transl_table=11
                     /translation="MAISCAGSLVTETFCRNGCLRCWPHLKLNRSHPWEKFMRDLDTLE
                     MAEEEGRLVTEIILEGRSKGKPSIRPEVRPEVQPEKAPRPIPEISPEKAPRPIPEIAPM
                     SPVPEVSPEKAPRPIPEIAPMSPVPEVSPEKAPRPIPEIAPSRPVPEIAPEKAPRPIPE
                     ISPEKTPRPVPEIAPDYPKKKDY"
     CDS             5001..6842
                     /gene_functions="biosynthetic (rule-based-clusters)
                     bacteriocin: TIGR03975"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="other (smcogs) SMCOG1277:Radical SAM
                     domain protein (Score: 164.4; E-value: 6.3e-50)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg228_51"
                     /sec_met_domain="TIGR03975 (E-value: 1.1e-165, bitscore:
                     544.3, seeds: 14, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.2e-14, bitscore: 47.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEEPIKPVALVSMPTLSARFPSFQLALLKPTLERAGMPVQTFSL
                     FMYFGNFIGWRINEALADVYPCMVGEWIWAKAAFGDFANDDEYFEIYHNNLEAICQPAG
                     CSIDDVRKIREQAVPEFIDFCLNSIDWTRFGVIGFSVVFQQTLASVAFARALKQRHPEI
                     PIIFGGATFEDDIAEEIMNGCPQVDYIHCGDADETLPQVIRRIYNNESMKGMPGVMWRD
                     RSAVAYTGRAPNLSDMNKTPVPDFDEYFYARKEGGYQNYDQAQEVLLPIETARGCWWGV
                     KNHCTFCGLNRAGMEFRSKHVDNVIEQLDELSQRYGILDFNAIDNIIAPEYIDKLFTRL
                     ADANTDIRLHYEVRPSLSRAQLKLMRKGGLFSIQPGVESLSTHILKLMRKHTTGMRNLE
                     LIKWSTYYGINNLYNILLRFPGETAEDYRTQCAVISKIHHLQAPWAIARARADRGSPMY
                     TEPESQSISRLVPSPCYDYLFPKDRFNLHRVSYYFEHEMGNTLADSEYDEIFEAVDTWQ
                     YRWRQRPRPYLRYRKAWATIIIDDGRNCSPHVTTYANNYAQLYEFCADARSAKEIAAEF
                     AGASWVDAALAEFVERDFMVHLDNRYLSIALPENAYF"
     CDS             6855..9719
                     /locus_tag="ctg228_52"
                     /transl_table=11
                     /translation="MLREPLSATLASFPQSFHAARCELLDLLRDRGILYRSPTQPILSR
                     DGTSGRWMLDSLAVTLSARGAELAGQCLLQLLQRFDGRQIATYGLTGVPLLQSCILQDH
                     RYRGLLVRKERKQHGSLKLIEGDIDPNEPVILLDDSVSSGMSMEEGTARLEEAGLRVEG
                     GVCLVRFGWYGGYASMQERGYHMEALYDIWDDFMSQMKDEEQPLANPSKSFPKFEWHAE
                     RAPERLQPAQLARVVISEYLSSGLLLRPPLRLDQEHDSSGGAWVSVRARSDIHQRFARG
                     GFWHFPDEAHGPAAEDVVLASLSTAAELSASEDGRRRLAESAIAVTFFSALERCSPGEL
                     DNDRYGIVVRSLERREWMGGALPRMPGIANEWQQFQHARIKNAKLASFEPYELFRHEVV
                     KVVELEVIWQPTGVATGSEPQWHKDKDVCGRVAERARDLVLARLFSRAPATVPLANDLL
                     PEQTESCYVTVYIDGQLRGCMGSVLRDLDKDLAQLAEAAIEDERFEGGAATDPDAVAVS
                     VSLLWNAFEMGQASPEEIVSYYLHGEHALMAYQGERLGLLLPFVASAWSYDRVSFAQAV
                     VEKAGLTDPPYYWCRFDCTTWLADDRGAWATVGGLPLEPSRTSVADLIERHLHYLLKHL
                     KPDGSFYSRYQPFQNRLYEAVDPARQAYGAYVLARAARILHRNDLQTAANTVIDALAKH
                     LSTDDDDLWLRFDDEIPSVAELSFLLLALCNLHNNAPQRSLIPIIATKLWRCIELPHGR
                     IATHPDPDPVLDPYQDYAPGQVLLALATAAAENASEIDHERLQRSFNYYRHRFRYKRHF
                     GQVTWLLQAFAKWWQVTKQQPFADLVFEVADWLLGYQQEKTGAFINDHQPDTPGYTTAV
                     YLEGLAAALLVATEQADKQRQANYDCSLARGVEFLDRLIIQERDRRILPNPDFALGGLR
                     QSLHYSEIRTDFVQHSLSALLARI"
     CDS             9806..10546
                     /NRPS_PKS="Domain: PKS_KR (7-120). E-value: 2.3e-11. Score:
                     35.7. Matches aSDomain: nrpspksdomains_ctg228_53_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     202.8; E-value: 1e-61)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg228_53"
                     /sec_met_domain="adh_short (E-value: 2.2e-33, bitscore:
                     107.7, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 6.4e-35, bitscore:
                     113.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LLEGKRAFVTGGTRGIGAAICEIFAREGADVAFSYNSRDDLAEEM
                     ERKIEAHGRRAFNAKVSVVDRVGMKKMTRELVEKWGGIDILVNNAAINRGDNFATTTDR
                     AWDEVIHTNVDSLFAVTKPIYKQMIRQRKGAILNITSIGAMRALPTAVHYATSKAAMIG
                     FTKCLSREAGTFGVRVNAIAAGIFDTDLAQALPDRLLQMHDFWTSAGRLGRPEELAEYA
                     AFMVSERNSFMNGEIVIVDGGAIT"
     aSDomain        9827..10165
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg228_53_PKS_KR.1"
                     /evalue="2.30E-11"
                     /label="ctg228_53_PKS_KR.1"
                     /locus_tag="ctg228_53"
                     /protein_end="120"
                     /protein_start="7"
                     /score="35.7"
                     /specificity="KR stereochemistry: C1"
                     /specificity="KR activity: inactive"
                     /tool="antismash"
                     /translation="FVTGGTRGIGAAICEIFAREGADVAFSYNSRDDLAEEMERKIEAH
                     GRRAFNAKVSVVDRVGMKKMTRELVEKWGGIDILVNNAAINRGDNFATTTDRAWDEVIH
                     TNVDSLFAVT"
     aSModule        9827..10165
                     /domains="nrpspksdomains_ctg228_53_PKS_KR.1"
                     /incomplete
                     /locus_tags="ctg228_53"
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       9830..9892
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg228_53_0001"
                     /evalue="1.80E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg228_53"
                     /protein_end="29"
                     /protein_start="8"
                     /score="17.4"
                     /tool="antismash"
                     /translation="VTGGTRGIGAAICEIFAREGAD"
     CDS             complement(10560..11594)
                     /locus_tag="ctg228_54"
                     /transl_table=11
                     /translation="MKLSELAELTGARIEGPNTDIEILGAAGLDEAGEEHVTFLANPRY
                     TPRVNTTRAAAIYLSEDAQTDREIAVLRVKDPYLAYTRALRIFHPEPKLDAHIHPSAVI
                     DPSARVATNVAIGAGSYIGRNAEIAEGVCIHPNVTVYEDVTVGKDSTIHSGVAIRERTV
                     IGERVVIYNNAVIGCDGFGYAKDEQKRWLKIPQTGRVVLEDDVEIGAGTTIDRASVGES
                     RIGRGTKLDNLVQIGHSCTVGEDSLLCAQVGLAGSSHIGNRVILAGQAGVAGHLTIGDD
                     VVLTAKSATSHDIPAGKIISGIPAFDNKDWLRSTAAFRRLGQLQRTVRELERKLATDDK
                     DKSA"
ORIGIN
        1 agtgtccggg cctgaacgtc accgtggcgc tcggcatcga tggcctaaag tcagagcacg
       61 agaagattcg ccagaaaccc ggttcgtggg acatcgccat cgatacggcg cgacagcttc
      121 aggagatcaa gaaacaacat ccgcaactcg atgtgcaaac gtgtacctgc tttatgaatt
      181 cgaaccagga cacgatcttc gagtggtacg actttctgaa gtacaacctc aagcctgaca
      241 aagtaaactt caactacatt cgcccgcctt cagccgatcc gaaagagctg gacatcgatc
      301 actcgcgtta cgcgcaactc gcgcagatga tcgacgacga ctcgcgtcac gccgcgatca
      361 agaacaacta caccggcaaa gccggattct tcaaagccgc gatcgacatt tacatgcacg
      421 ggctgatcgc gaagacgcag gaaacacagc aagcgcaaat gaagtgttac gccggcaccg
      481 cgggcggagt catctacgac gaggggactg tttcgtcttg cgagaacctc gcgccgatcg
      541 gcaacctgcg cgagtttgac tggaactttc aaaagctttg gttgtcgccg gcgatgaaag
      601 aacgtcgcca gcacgcggcg aacggttgtt tctgcacgca cgagtcgaat agttactacc
      661 cgtcgctgcc gttcaacccc ggccacttga tcaagatcaa gaaactggag cgcgagatga
      721 agaagtcgcg ccatgaaatc gacggcggtt tgtcagtcgg tgatctaaaa acaaccgaga
      781 tctaaatgcc ggatcaaccc cgcataccga agatactcat catctcctcc gataccggtg
      841 gcggtcatcg ctccgccgcg gccgcgatcg tggccggcgt gcagaagttt ctcgatagcg
      901 aatcctacgc gatccgcgtg gtgcgcgcgg tcgaggaatc acaccacctc gccgacaagc
      961 tggtccgtct ttacaactgg atcctgcgca atcggcagca ctggatgaaa tactattact
     1021 ggttcatcaa tcgtattcgt ccggacacgc gcgaattttt tcataaacgc tgcgtcggtt
     1081 acgttcgtgg cctgttcgaa cgctggtgcc cgcacatcgt cgtcagcgtg cacccgttga
     1141 cgcaacacat cttcgggcgc gtgctcaaag acttgaacct cgccgatcgc gtgccgctgg
     1201 tttccgtagt taccgatcct tgttacggct tctggaaagg ctgggcctgc gacgcggtga
     1261 cgctttatct ggtcgccagc gaagaagcgc aacggcagtt gatcgactac ggcgtggcgc
     1321 cggaacgcat caagatctcc ggcatgccgg tccatccgaa gtttgcttat cccggcgaag
     1381 aagcggccca ggccgcgcgg cgcgcactcg gtctcgatcc ggaaaagttc accgtcttcg
     1441 tcaacgccgg ctggatcggc ggcggcaaca ttccgcagat ctttcgcgaa ctcgtgcgcg
     1501 gcgagctcga cgtgcaggcc attttcctcg ccggcaagaa tgaagacctg cgcgcggttg
     1561 ctgaaacgat cgcgcgggac gcgccgtttc cgatcaaagt cattggttac tccgatgaga
     1621 tcgagcagtt gatgagcgcg gccaacgtga tgatttccaa actcggcggc ctcacgactt
     1681 ttgaagccct cgcctgtcgt gtgcccatca tcgctgacgt gatcaccgat ccgatgccgc
     1741 aggaagcggg caccgcaaga ctgatcgcgc aacgcggcgc cggtgtgatg ctcaagcatt
     1801 cgagcgacgt cgtggctgtc gtgcggcgca tggtggaaga cgaagtccac tactcacgaa
     1861 tgcgcgccgc gaccgttggc ctggccattc ccaacgcgac ccggcacatc gtcgaagaga
     1921 tcgccgctct cattccgcca tctgaaaaag cagtactaaa cgaagtcgtc tcagcctgat
     1981 ttcatcgcgc gcgcgcgcaa aggcttcgtg tcctcaatgg acaaagaacc gtgggtcctc
     2041 ggaataagcg cctcgcataa cggttcagtc tgcctgctcc acggcgacga gattgtcgtc
     2101 gcaattcagg aagaacgtct ttcccgcgtc aagcgtcatc gcatttacgg aaaaggacca
     2161 tccctcgcga ccagctattg cctgagttat gccggaatcg aacccgccga actggatctg
     2221 atcgtgttgt gcgtgcaggg gcggttgagc gacgaggtca acgacattcg cctggagccg
     2281 ttgctgaata tccaggcgca tcgcacgccg gtggtggcga taccgcatca ctacggacac
     2341 gccttcagcg cgtttgccac ctcgggcttc gaggaatcgg cgattctggt cgtcgatggc
     2401 accggctcgc cggccaccga ttttacggcg gcagagaaga gcattctcaa cggccacgcg
     2461 gaaaatggct gggaaacaat ctcgctctat tacggcagcg gaactgacat tacgccgctg
     2521 gagaagcacg ttgtcgatcg cggcgcgtgg ttgctgatgc acgacggcga gatgccggcg
     2581 tttggcagtt tgggtggaat gttttccgcg gcggcggaac agatcttcgg cgaagtgact
     2641 gaagccggaa aggtgatggg cctcgcgggt tacggcaaac cggaatttcc ggcgcgcgat
     2701 tttttcgaga tcgagaacgg gcggtttcat ttcaaagata aggtgccgca gcagtttcgg
     2761 cataacgtgc gttggcctga agccgcgccc gagtatgaaa cattggctgc ttcggtgcag
     2821 ggtgcgctcg aagatgcgtt gctgtacctg gtccggcatc tgcgcgagtt gtgcccgagc
     2881 cggaatcttt gttacgcggg cggcgtggcg ttgaatagcg tcgcgaacga gcggctgatt
     2941 cgcgagtcgg gttacgacca gatttacatc atgccggcgg cggaagacag cggcgctgcg
     3001 gtcggcgcgg cttattacgg gctgtggcaa ctgaccgggt gcaacttgcg acggcggttg
     3061 ccgcacgatg cgttggggcg gagttattca gccacggagg taacggacgt tttggagcga
     3121 gtgtcggaag ttcgctcggt ccgctcgaca gacgtcatcc gagacgcggt tgagttgttg
     3181 tgcgacggga agatcatcgg ctggttcgac ggcggctcgg aacttggccc aagagcgttg
     3241 ggccaacgaa gcattctctg cgacccgcgc agtccggatg cgaaggcgac gctcaaccgg
     3301 cgcgtgaaga tgcgcgaagc gtttcgcccg tttgcgccgg cggtgttgct tgaagcagcg
     3361 ccacagtggt ttgagtttgg cggttcagcg ccggaaagcc cgtttatgtt gcgcgtctgt
     3421 gaagtgaagc aggagaagaa agacgaggtg cccgcgatcg tgcacgtcga cgccaccggc
     3481 cgcttgcaaa cactgacgcg tgaagcgaac ggcagatttt atgagttggt gaagcagttt
     3541 tacgagcgga cgggtgtgcc gatgctgctc aacacgtcct tcaatcgcat gggcgaaccc
     3601 atcgtcgaaa cacccgccga cgcgatcggg tgtttgctcc gaacggacct tgattgctgc
     3661 gtgtttgcgg atagaatcgt ttggaaaaat ggctgagttg agtgcctcac attttaatct
     3721 gtacctggcg ccgcactttt tcgacgccgg agaatgtgcg cgactgctgg ccgcgttgcg
     3781 cccgtctccc accactcagg cgcccgtcta catcgaaggc tctgacaggt ttgttcacga
     3841 agatgtgcgg cgaacaacga gtcttcatcc ggcagacgaa attttttcgg tcgtgcatag
     3901 ccggcttttt gaagaaaagc cggcgctgga aaaacatttc ggcctcactt tgactgactg
     3961 cgagcggccg caatttctgc gttaccaaac gggcgacttc ttcgtccgtc atcaggacgg
     4021 caacaccgaa caactccagt ttgaccacct gcgaattcgc cgcatctcgc tcatcgtgtt
     4081 tctcaacgaa cacacgggcc aaccgcaagc tgattctttc tccggcggtt cgctcaattt
     4141 ctacgacctg aacgaagctg ggccagacgg cccaaccgcc tttcctctct tcggcgaaac
     4201 cgggctgctc gttgctttca ccgccgaaac gatgcacgaa gtcgctcccg taacgaacgg
     4261 cgaacggttc accgtcatca gttggtttcg ctgatttttg ttgacacaca cccgagatgg
     4321 caataagctg cgccggttcc ctcgtaaccg aaaccttctg ccgcaacggc tgtttgcgtt
     4381 gctggcctca cttgaaactc aaccgctcac atccctggga gaaattcatg agagatctag
     4441 atacgctcga gatggccgag gaagagggcc ggctggtaac tgaaatcatt ctggaaggcc
     4501 gctcgaaagg taagccgtcg atccggcccg aagtgagacc ggaagttcaa ccggagaagg
     4561 caccgcgccc gataccggaa atctcgccgg agaaagcgcc acggcccatt cccgagattg
     4621 cgccgatgag tcccgtgcct gaagtgtcgc cggagaaagc gccgcggccc attcccgaga
     4681 ttgcgccgat gagccccgtg cccgaagtgt cgccagagaa agcgccgcgg cccattcccg
     4741 agattgcgcc gtcgcgcccg gttccggaaa tagcaccgga gaaagcaccg cgtccgatac
     4801 ctgagatttc gccggagaag acgccgcggc ccgtgccgga aatcgcgccg gattacccga
     4861 aaaagaaaga ctactgagcg cttatccgtg aattagtgtt tgagtatatc gaaccccgac
     4921 gtggccggtg gcatttggat gtgtggttta cacggatctg aaagccatcg accagtcggg
     4981 tgaagtttac gttaaagtcc atgagcgaag agccaatcaa accggtcgct cttgtcagca
     5041 tgccgacgct ctcggcgcgc ttcccgtcat ttcagctcgc gttgctcaag cccaccctcg
     5101 aacgcgcggg catgcccgtg caaacctttt cgctcttcat gtacttcgga aacttcatcg
     5161 gctggcgcat caatgaagcg ctcgcagacg tctatccgtg catggtcggc gagtggatct
     5221 gggccaaagc cgcgtttggc gactttgcca acgatgacga gtacttcgag atctatcaca
     5281 acaatctcga ggcgatttgc cagccggcgg gttgctcgat cgacgacgtg cgcaagattc
     5341 gcgagcaagc cgtgccggag ttcatcgact tctgcctgaa cagcatcgat tggaccaggt
     5401 tcggcgtgat cggtttttca gtggtgtttc agcaaactct agcgagcgtt gctttcgcgc
     5461 gcgcgttgaa acagcgtcac ccggagattc caatcatctt tggcggcgcg acgtttgaag
     5521 acgacatcgc cgaagagatc atgaacggct gcccgcaagt cgattacatc cattgcggtg
     5581 acgccgacga aacgctgccg caagtgattc ggcgtattta caacaacgag tcgatgaagg
     5641 gcatgccggg tgtcatgtgg cgcgaccgct ccgcagttgc ttacaccgga cgcgcgccaa
     5701 acctcagcga catgaacaag acgccggtgc cggacttcga cgagtatttc tacgcacgca
     5761 aggaaggtgg ttatcaaaac tacgatcagg cgcaggaagt attgctgccg attgaaacgg
     5821 cacgcggttg ctggtgggga gtgaagaacc attgcacctt ctgcggactc aatcgcgcgg
     5881 gcatggagtt tcgctcgaag cacgtcgaca acgttatcga acagctcgac gaactgtcac
     5941 agcgctacgg catcctcgat ttcaatgcga tcgacaacat catcgcgccc gagtacatcg
     6001 acaagctctt cacccggctc gccgatgcga acactgacat tcgcctgcat tacgaagtgc
     6061 gcccgagcct cagccgcgca cagctcaagc taatgcgcaa aggtggcctg ttctcgatcc
     6121 agccgggcgt ggagagtttg tcgacgcata ttctcaagct catgcggaag cacacgacag
     6181 gcatgcgcaa cctcgagttg atcaagtggt ccacctacta cggcatcaac aatctttaca
     6241 acatcctgct gcgcttcccg ggtgaaactg ccgaagacta ccgcacgcaa tgcgccgtaa
     6301 tctcgaagat tcatcacctg caggcgccgt gggccatcgc cagggcgcgc gcggatcgtg
     6361 gctcgccgat gtatacagaa ccggagtcgc aatcgatcag ccgtctggtt ccgtcgcctt
     6421 gctacgacta cctgtttccg aaggatcgtt tcaatctcca ccgcgtctcg tattacttcg
     6481 aacacgaaat gggaaacacg ctggcagaca gcgagtacga cgagatcttc gaggccgtcg
     6541 acacgtggca atatcgctgg cgccagcgcc cgcggccgta tcttcgttat cgaaaagcgt
     6601 gggccacaat catcatcgac gacggccgca actgttcgcc tcacgtgacg acctatgcga
     6661 acaactacgc gcagctttac gaattttgcg ccgacgctcg tagcgcgaaa gagatcgccg
     6721 cggagtttgc aggcgcatcg tgggtcgacg ccgcgctcgc agagtttgtc gagcgagatt
     6781 tcatggtcca cctcgacaat cgttacctga gcatcgcgct acccgagaac gcgtacttct
     6841 aagattgcac gccgatgttg cgcgaaccgc tgtcagctac tctcgcctcg tttccccaga
     6901 gttttcacgc agcccgctgt gaactgctcg acctgctgcg cgatcgcggc atactctatc
     6961 gctcaccaac gcaaccgata ctttcacgcg acggcacgtc gggccgctgg atgctcgatt
     7021 cgctggcggt cacgctctcg gctcgtggcg ctgaactcgc aggccagtgt ttgctgcaac
     7081 tgctccagcg attcgatggg cggcagatcg cgacttacgg tttgaccggc gtgcctctgc
     7141 tgcagtcgtg cattctgcag gaccatcgtt atcgcggctt gctcgtgcgc aaagagcgga
     7201 agcaacacgg atctctgaag ctcatcgaag gcgacatcga tccaaacgaa ccggtgatcc
     7261 tgctcgacga ttcggtgagt tcgggaatgt cgatggagga gggcaccgcg cgtttggaag
     7321 aggcgggcct acgcgttgag ggcggtgttt gcctcgtgcg ttttgggtgg tacggcggtt
     7381 acgcgtcgat gcaggagcgc ggctatcaca tggaagcgct ctacgacatc tgggacgatt
     7441 tcatgtcgca gatgaaggac gaagagcagc cgctggcgaa tccgtcgaag tcgtttccga
     7501 aattcgagtg gcatgcggaa cgagcgcccg aacggctgca gccggcgcaa cttgcgcgcg
     7561 tcgtgatttc ggaatacttg tcgtcgggac ttctattgcg gccgcctttg cggttggacc
     7621 aggagcacga ctcgtcgggt ggcgcgtggg tcagtgttcg tgcgcgcagc gacattcatc
     7681 agcgctttgc gcgcggcggg ttttggcatt ttccggatga agcgcatggt cccgcggccg
     7741 aagacgtggt gctggcgtca ttgagcacgg cggcggagtt gtcggctagt gaagatggac
     7801 ggcggcgtct cgctgagagc gcgatcgcag tcacgttttt cagtgcgctc gaacgatgca
     7861 gtccgggcga gcttgataac gaccgttacg gcattgtggt gcgaagtttg gaacgacgcg
     7921 aatggatggg cggcgcgttg ccgcgcatgc caggcatcgc aaatgagtgg cagcagtttc
     7981 agcacgcgcg catcaagaat gcgaagctgg cctcgtttga gccgtacgag ctgtttcgtc
     8041 acgaggtggt gaaggtcgtc gaactggaag tgatctggca accgaccggt gtggcaacag
     8101 gaagcgaacc gcagtggcac aaggacaagg atgtttgcgg ccgagtcgcg gaacgcgcgc
     8161 gcgatctggt tttggcgcga ttgttcagtc gtgcgccggc gaccgtgccg ctggcgaacg
     8221 atctgctgcc ggagcagacc gaatcgtgct acgtcacggt ttacatcgac ggacagttgc
     8281 gtggctgcat gggctcagtg cttcgtgacc tcgataaaga tctggcgcaa ctggccgaag
     8341 ccgcgattga ggacgagaga ttcgaaggcg gcgcggcgac ggatcccgat gccgtggcgg
     8401 tgagtgtgtc gctgctttgg aacgcgtttg agatgggaca agcgtcgccc gaagagattg
     8461 tgagttatta cctgcacggc gagcacgcgt tgatggccta tcaaggcgaa cgactcggct
     8521 tgctcttgcc cttcgtcgcg tcggcctgga gctacgatcg cgtgagtttt gcgcaagcgg
     8581 tggtcgagaa ggcaggactg actgacccgc cgtattactg gtgccgcttt gattgcacga
     8641 cgtggttggc ggatgatcgc ggcgcctggg ccacggtggg cggcttgcct ttggagcctt
     8701 ccagaacttc agttgccgat ctcatcgagc gacaccttca ttacttattg aagcacctca
     8761 aacccgacgg cagcttctac tcgcgctatc agccctttca aaaccgactc tacgaagccg
     8821 tcgatcccgc acgacaagcc tacggcgcgt acgtgctcgc ccgcgccgct cgcattctgc
     8881 accgcaacga tcttcaaacc gccgccaaca ccgtcatcga cgcgctcgcg aaacatctct
     8941 ccaccgatga cgacgatctg tggctccgct tcgacgacga aatcccttcc gtcgccgaac
     9001 tctcgtttct cctattggcc ctctgcaact tacacaacaa cgctccccag cgatctctga
     9061 tcccaatcat cgccaccaaa ctctggcgct gcatcgaact cccccacggc cgcattgcca
     9121 cccacccgga ccccgatccc gtcttagatc cctaccagga ttacgcaccc ggacaagtgt
     9181 tgctcgcact cgcaaccgcc gccgcggaaa acgcgagcga gatcgatcac gaacgactcc
     9241 agcgcagctt caactactac cgccatcgct ttcgttacaa acgccatttc ggccaggtca
     9301 cctggctcct tcaggccttt gcgaagtggt ggcaagtcac caaacagcaa ccgttcgcgg
     9361 atctcgtttt cgaagtcgcc gactggctgc ttggttatca acaggaaaag accggcgcgt
     9421 tcataaacga ccatcagccg gacacgcccg gttacaccac cgccgtttat ctcgaaggcc
     9481 tcgcggccgc gctcttggtt gccaccgaac aagccgacaa acaacggcag gcaaactacg
     9541 attgttccct cgcgcgcggc gtcgaatttc tcgatcgcct gatcattcag gagcgagatc
     9601 ggcgcattct cccgaacccg gatttcgccc tgggcggcct gcgccagagt ctccattaca
     9661 gcgagatccg gaccgatttc gtgcagcatt cactctccgc cctgctggcg cgaatttgac
     9721 tgctccgcgc ctttcacggt ttaatcctcc gtcatttaaa ctagccccgg acttaattca
     9781 ggagaaagat agctaagtga gccttttgct tgagggaaaa cgcgcgttcg ttaccggtgg
     9841 aacgcgcggt attggcgccg ccatctgcga gatctttgcc cgcgaaggcg cggacgtagc
     9901 tttcagctac aacagtcgtg acgatctcgc tgaggagatg gagcgcaaga tcgaagctca
     9961 cggacgtcgc gcgttcaacg cgaaggtctc cgtcgtggac cgcgtcggca tgaagaagat
    10021 gacgcgcgag ttggtcgaga agtggggcgg tatcgacatc ctcgtcaata atgccgccat
    10081 caatcgcggc gacaacttcg ccaccacgac cgatcgcgcg tgggacgaag tgattcacac
    10141 gaacgtcgac agtctctttg cagtcaccaa gccgatttac aagcagatga ttcgccagcg
    10201 caaaggcgcc atcctcaaca tcacctcgat cggcgcgatg cgcgcgttgc cgacggcggt
    10261 gcattacgcg acttcgaaag cggcgatgat cggttttact aagtgtctct cgcgtgaggc
    10321 ggggacgttt ggcgtgcgcg tcaacgcgat tgcggccggc atattcgaca ccgatctcgc
    10381 gcaggcgtta ccggatcggt tgctgcagat gcatgatttt tggacctcag ccggccgcct
    10441 cggccgcccg gaagaactcg ccgagtatgc ggcgttcatg gtgagcgagc ggaatagttt
    10501 tatgaacggc gagatcgtga tcgtggacgg cggcgcgatc acgtaaagcc atccacagat
    10561 tacgcagatt tatctttgtc atccgtggcc agttttcttt ccaactcacg caccgtccgt
    10621 tgaagctgtc cgaggcgcct gaaagctgcc gtagatctaa gccagtcttt gttatcaaac
    10681 gccggaatac cggaaatgat ctttccggcc ggaatgtcgt gactggtcgc actcttcgcc
    10741 gtcagcacga cgtcgtcgcc gatcgtcaaa tgtcctgcga cgcctgcctg tcccgccaaa
    10801 atcacccgat tgccgatatg tgaactgccc gcgagcccga cctgcgcaca cagcaacgaa
    10861 tcttcaccga cagtacacga gtgaccaatc tggaccaggt tgtcgagctt cgtgccgcgc
    10921 ccgatgcggc tctcgccgac tgaagcgcga tcgatggtag tgccggcgcc aatctcgacg
    10981 tcgtcttcaa gcaccacacg cccggtttgc ggaatcttca gccaacgctt ttgttcgtct
    11041 ttcgcgtaac caaaaccgtc gcaaccaata acggcgttgt tgtaaatgac gacgcgttcg
    11101 ccgatcacgg tgcgctcgcg aatggcgacg cccgaatgaa tcgtcgagtc ttttccgacc
    11161 gtcacgtctt catagacagt cacattggga tgaatgcaga cgccttccgc gatctcggcg
    11221 ttgcggccga tgtaagagcc ggcgccgata gccacgttag tggcgacgcg tgcggatgga
    11281 tcgattacgg ccgacggatg aatgtgcgcg tcgagctttg gctcgggatg aaagatgcgc
    11341 agcgcgcgcg tgtacgcgag atacggatct ttcactcgca ggacggcgat ctcgcgatcg
    11401 gtctgcgcgt cttcgctgag atagatcgcg gcggcgcgcg tcgtgttgac gcgtggggtg
    11461 taacgcggat tggcgagaaa agtgacgtgc tcttcgcccg cttcgtcgag cccggcagcg
    11521 ccgagaatct cgatatccgt gtttggtcct tcgattctgg cgccggtcag ttcagcaagt
    11581 tctgaaagtt tcattaagga cctcacatta tcgaaacggg atcgatctct aagttgatgg
    11641 aacgtaaatt caagccttgt tcggaagctg atttcaacgc cgcgtccgct acctcgcgca
    11701 ggtggcggcg gctgcgtgat ttcagcagga gctggaaacg gtgttcgccc tttagccgcg
    11761 cgagcggcgc gggcgcgggg ccgagtatgc ggcagtgacg ctgctcgttc gcggcgtcaa
    11821 gctgcttgcg cagttcgagg ct
//
