LOCUS       c00256_3300024..        5840 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300024186.a:Ga0247688_1000907.
ACCESSION   c00256_3300024..
VERSION     c00256_3300024..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 09:28:56
            Original ID  :: 3300024186.a:Ga0247688_1000907
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5840
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5840
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1674:5838](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(1675..5838)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..5840
                     /SMILES="NC(C(C)CC)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5840
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             complement(2..1678)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="other (smcogs) SMCOG1277:Radical SAM
                     domain protein (Score: 197.4; E-value: 6.2e-60)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg256_1"
                     /sec_met_domain="PF04055 (E-value: 1.3e-21, bitscore: 64.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLVSIGRSDALRKLAGVDPKERKILLVKPPYFSPWTPPLGIAIL
                     KSFLEPHGYEVRCYDFNSDPELWGMHHKYFSVLQTLEDVSINDGYSKLWWILNAHMLAF
                     ANGADPAACAKVLSSVVPLQGMRISQGVIRQLLPLVENFYQRLNVLTEEFNLAEYGTVG
                     TSTYTTSLGPSLFFLKRVKEQHPNIRTIMGGGAFADDLALGSDNLDTLVREYDFIDHFV
                     LGEGELLLLKLLQGDFAGQRLISLADLHGVTLEMKDVPIPDFSDVGTENYYHLTIEGAR
                     SCPFQCSFCSETIQWGDYRKRPMQAFADQVSDLAKRYNNNSFFMGDSLMNPYINQFAGQ
                     LLDRKANILYDGYLRADKPVANRAFVKMWADSGCYRVRLGIESAAARVLDSMDKMTTPK
                     VISDVLKTLANAGIRTTTYWITGFSGETEEDFRETCEFIREHHRYIYELEAHAYYYYPY
                     GQIGSRLHECRSLYPDEVTDIIKFKVWEIKDANPPRVERFDRLRRVSALASELGLPNIY
                     TMAERFAAEERWHRLHPLALEVYEGTRLHRDVPSLPETEIPA"
     CDS             complement(1675..5838)
                     /NRPS_PKS="Domain: Condensation_LCL (0-154). E-value:
                     3.6e-63. Score: 205.1. Matches aSDomain:
                     nrpspksdomains_ctg256_2_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (317-715). E-value:
                     2.2e-110. Score: 360.8. Matches aSDomain:
                     nrpspksdomains_ctg256_2_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (828-895). E-value: 2.3e-22. Score:
                     70.7. Matches aSDomain: nrpspksdomains_ctg256_2_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (915-1215). E-value:
                     4.7e-115. Score: 375.4. Matches aSDomain:
                     nrpspksdomains_ctg256_2_Condensation_LCL.2"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 376;
                     E-value: 3.9e-114)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg256_2"
                     /sec_met_domain="Condensation (E-value: 2.3e-84, bitscore:
                     270.1, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.7e-116, bitscore:
                     376.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7.6e-18, bitscore:
                     52.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LVKEVGTLYEAYSQGNESPLEELPLQYADYAVWQRGWLQDEVLEQ
                     QLSYWREQLNGAPVLELPVDHVRPAVQTYRGAAQSLQVRKEVLAELKALSRREGVTLFM
                     TLVAAFQTLLSRVSGQEDIVVGTGIANRTRGEVEGLIGFFVNTLALRTDLSGDPTFREL
                     LGRVREVTLGAYAHQDVPFEKLVEEVELERGVGHMFQVMFAMSNMPMPELELAGVTLTA
                     EERECETAKSDLILAATEREGELGFKLEYSTELFEAETITRLLQHLATLLADIGRDADQ
                     RLSALRLLTAAEENQLLCEWNQTNAPYPREHSIHALFETQAAATPDAVAVVAGETMLSY
                     AELNRRANQLAHHLRSLGVSAEVPVGICLERSAELIVGLLGILKAGGVYVPLDASYPEA
                     RLRLMLEDAGVSLVLTTEQFAELFVTNETVRLIDMEETLSGYSQDDPEAAVGPGNLAYV
                     MYTSGSTGRPKGVSITHRSVVRLVRDTEYVQLTSDDRIAQAANPAFDAATFEIWGSLLN
                     GARLVIIRREVTISPEEFAWEIENLGLTVLFLTTALFNQIARRIPEAFASLKYLLFGGE
                     AVDPQWVREVLAKGAPQHLLHVYGPTENTTFSSWFPVREVPDSAVTIPIGKPITNTTAY
                     VLDRRLQPVPIGVIGDLYAGGDGLMRGYLNEPALTAESLIPNPHSSVAGERLYRTGDLV
                     RLLSDGSIEFAGRADSQVKIRGFRIEPNEIAAVLREEPGVEDSVVLVRRSPTGDQQLVA
                     YCAVNGDAGNGADAAAQLRKQLQEKLPEYMVPSQFVLLDHLPLTPNGKVDREKLAALAT
                     TEPESESEFIPAKTPVEELLTHIFATILDLDSIGANDDFFQVGGHSLLATQVMSRVRET
                     FKIQIPLTALFEYSTVASLAPHIEAAIQASAGVVTPIIARGEAAEPLPLSFGQQRLWFV
                     DQLQSGTAAYNVPLAMRLTGPLNVSALEQSFTEIIRRHESLRTCFPERDGQPVQLINPA
                     EPFTLPVSDLADLPVSEREATAIRMAQAEMNQPFTLSTGPLLRIKLLRLSDSEHIVVVT
                     MHHIISDGWSMNNLIEEMGALYAAYRDGQPSPLPAPAIQYGDFTLWQREWMQSDVLEKQ
                     IKYWAEKLSGLSTLELPIDRPRVEGQSLRGLTQKAAFSPELSQEVKRLSRESGTTQFMT
                     MLAAFKSLLHRYSGQEDIVVGTTVANRNHPETEKLMGFFVNMLVLRTDLSGNPTFRELL
                     QRVKEVTLGAYMHQDLPFDKLVEALRPERTLSSNSLFQVVFGVQHARELTLPELDIKLS
                     AVNVDWQATQFDLIVRATETSEGLTLLMTYSSDLFEPQTIARLLKHYEAWLTAVVADPD
                     SRLLDIPLRLDGKAAAAGESPADLTLPFATDQFSFGLPVERTRS"
     CDS_motif       complement(1687..1725)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg256_2_0013"
                     /evalue="3.40E+01"
                     /label="C3_starter_134-155"
                     /locus_tag="ctg256_2"
                     /protein_end="1384"
                     /protein_start="1371"
                     /score="-2.1"
                     /tool="antismash"
                     /translation="ATDQFSFGLPVERT"
     CDS_motif       complement(2038..2154)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg256_2_0012"
                     /evalue="7.90E-22"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg256_2"
                     /protein_end="1267"
                     /protein_start="1228"
                     /score="69.7"
                     /tool="antismash"
                     /translation="KEVTLGAYMHQDLPFDKLVEALRPERTLSSNSLFQVVFGV"
     aSDomain        complement(2194..3093)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg256_2_Condensation_LCL.2"
                     /domain_subtype="Condensation_LCL"
                     /evalue="4.70E-115"
                     /label="ctg256_2_Condensation_LCL.2"
                     /locus_tag="ctg256_2"
                     /protein_end="1215"
                     /protein_start="915"
                     /score="375.4"
                     /tool="antismash"
                     /translation="EPLPLSFGQQRLWFVDQLQSGTAAYNVPLAMRLTGPLNVSALEQS
                     FTEIIRRHESLRTCFPERDGQPVQLINPAEPFTLPVSDLADLPVSEREATAIRMAQAEM
                     NQPFTLSTGPLLRIKLLRLSDSEHIVVVTMHHIISDGWSMNNLIEEMGALYAAYRDGQP
                     SPLPAPAIQYGDFTLWQREWMQSDVLEKQIKYWAEKLSGLSTLELPIDRPRVEGQSLRG
                     LTQKAAFSPELSQEVKRLSRESGTTQFMTMLAAFKSLLHRYSGQEDIVVGTTVANRNHP
                     ETEKLMGFFVNMLVLRTDLS"
     aSModule        2194..3093
                     /domains="nrpspksdomains_ctg256_2_Condensation_LCL.2"
                     /incomplete
                     /locus_tags="ctg256_2"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(2203..2292)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg256_2_0011"
                     /evalue="2.80E-17"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg256_2"
                     /protein_end="1212"
                     /protein_start="1182"
                     /score="55.0"
                     /tool="antismash"
                     /translation="DIVVGTTVANRNHPETEKLMGFFVNMLVLRT"
     CDS_motif       complement(2542..2580)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg256_2_0010"
                     /evalue="1.10E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg256_2"
                     /protein_end="1099"
                     /protein_start="1086"
                     /score="17.9"
                     /tool="antismash"
                     /translation="QYGDFTLWQREWMQ"
     CDS_motif       complement(2629..2694)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg256_2_0009"
                     /evalue="1.10E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg256_2"
                     /protein_end="1070"
                     /protein_start="1048"
                     /score="33.9"
                     /tool="antismash"
                     /translation="MHHIISDGWSMNNLIEEMGALYA"
     CDS_motif       complement(2911..3027)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg256_2_0008"
                     /evalue="5.70E-21"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg256_2"
                     /protein_end="976"
                     /protein_start="937"
                     /score="66.9"
                     /tool="antismash"
                     /translation="AAYNVPLAMRLTGPLNVSALEQSFTEIIRRHESLRTCFPE"
     aSDomain        complement(3154..3354)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg256_2_PCP.1"
                     /evalue="2.30E-22"
                     /label="ctg256_2_PCP.1"
                     /locus_tag="ctg256_2"
                     /protein_end="895"
                     /protein_start="828"
                     /score="70.7"
                     /tool="antismash"
                     /translation="EELLTHIFATILDLDSIGANDDFFQVGGHSLLATQVMSRVRETFK
                     IQIPLTALFEYSTVASLAPHIEA"
     aSModule        3154..5838
                     /complete
                     /domains="nrpspksdomains_ctg256_2_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg256_2_AMP-binding.1"
                     /domains="nrpspksdomains_ctg256_2_PCP.1"
                     /locus_tags="ctg256_2"
                     /monomer_pairings="ile -> ile"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(3667..3729)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg256_2_0007"
                     /evalue="2.40E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg256_2"
                     /protein_end="724"
                     /protein_start="703"
                     /score="32.5"
                     /tool="antismash"
                     /translation="FAGRADSQVKIRGFRIEPNEIA"
     aSDomain        complement(3694..4887)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg256_2_AMP-binding.1"
                     /evalue="2.20E-110"
                     /label="ctg256_2_AMP-binding.1"
                     /locus_tag="ctg256_2"
                     /protein_end="715"
                     /protein_start="317"
                     /score="360.8"
                     /specificity="consensus: ile"
                     /tool="antismash"
                     /translation="FETQAAATPDAVAVVAGETMLSYAELNRRANQLAHHLRSLGVSAE
                     VPVGICLERSAELIVGLLGILKAGGVYVPLDASYPEARLRLMLEDAGVSLVLTTEQFAE
                     LFVTNETVRLIDMEETLSGYSQDDPEAAVGPGNLAYVMYTSGSTGRPKGVSITHRSVVR
                     LVRDTEYVQLTSDDRIAQAANPAFDAATFEIWGSLLNGARLVIIRREVTISPEEFAWEI
                     ENLGLTVLFLTTALFNQIARRIPEAFASLKYLLFGGEAVDPQWVREVLAKGAPQHLLHV
                     YGPTENTTFSSWFPVREVPDSAVTIPIGKPITNTTAYVLDRRLQPVPIGVIGDLYAGGD
                     GLMRGYLNEPALTAESLIPNPHSSVAGERLYRTGDLVRLLSDGSIEFAGRADSQVKIRG
                     "
     CDS_motif       complement(3820..3906)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg256_2_0006"
                     /evalue="1.70E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg256_2"
                     /protein_end="673"
                     /protein_start="644"
                     /score="42.7"
                     /tool="antismash"
                     /translation="PIGVIGDLYAGGDGLMRGYLNEPALTAESL"
     CDS_motif       complement(4414..4473)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg256_2_0005"
                     /evalue="5.00E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg256_2"
                     /protein_end="475"
                     /protein_start="455"
                     /score="31.3"
                     /tool="antismash"
                     /translation="AYVMYTSGSTGRPKGVSITHR"
     CDS_motif       complement(4660..4701)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg256_2_0004"
                     /evalue="1.30E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg256_2"
                     /protein_end="393"
                     /protein_start="379"
                     /score="18.3"
                     /tool="antismash"
                     /translation="LGILKAGGVYVPLDA"
     CDS_motif       complement(5224..5337)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg256_2_0003"
                     /evalue="3.70E-18"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg256_2"
                     /protein_end="205"
                     /protein_start="167"
                     /score="57.9"
                     /tool="antismash"
                     /translation="REVTLGAYAHQDVPFEKLVEEVELERGVGHMFQVMFAMS"
     aSDomain        complement(5377..5838)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg256_2_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="3.60E-63"
                     /label="ctg256_2_Condensation_LCL.1"
                     /locus_tag="ctg256_2"
                     /protein_end="154"
                     /protein_start="0"
                     /score="205.1"
                     /tool="antismash"
                     /translation="LVKEVGTLYEAYSQGNESPLEELPLQYADYAVWQRGWLQDEVLEQ
                     QLSYWREQLNGAPVLELPVDHVRPAVQTYRGAAQSLQVRKEVLAELKALSRREGVTLFM
                     TLVAAFQTLLSRVSGQEDIVVGTGIANRTRGEVEGLIGFFVNTLALRTDLS"
     CDS_motif       complement(5386..5475)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg256_2_0002"
                     /evalue="3.00E-15"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg256_2"
                     /protein_end="151"
                     /protein_start="121"
                     /score="48.5"
                     /tool="antismash"
                     /translation="DIVVGTGIANRTRGEVEGLIGFFVNTLALRT"
     CDS_motif       complement(5725..5763)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg256_2_0001"
                     /evalue="1.70E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg256_2"
                     /protein_end="38"
                     /protein_start="25"
                     /score="20.3"
                     /tool="antismash"
                     /translation="QYADYAVWQRGWLQ"
ORIGIN
        1 aagccggaat ttctgtctcc ggcagcgaag gaacatctcg atgcaatcgg gttccttcgt
       61 acacttcgag cgcgagcggg tgcagccggt gccaacgttc ttccgcggca aagcgttcgg
      121 ccatcgtgta gatgttcggc aggcccagct ccgacgcgag cgcggaaacg cgtcgcaagc
      181 gatcaaaacg ctcgacgcgc ggcgggttgg cgtctttgat ctcccacact ttgaacttga
      241 tgatgtccgt tacttcgtcg ggatagagcg aacggcactc gtgcaatctc gatccgattt
      301 ggccgtaggg atagtagtag taagcgtgtg cttcgagttc gtagatgtag cgatgatgtt
      361 cgcgaatgaa ctcgcacgtt tcccgaaagt cctcttcggt ctccccggag aagccggtga
      421 tccagtaagt agtggtgcga atgccggcgt tggcgagtgt cttcagaacg tctgaaatga
      481 ccttcggcgt agtcatcttg tccatcgaat ccaacacgcg cgcggcggcg ctctcaatgc
      541 ccaggcgcac gcgatagcaa ccggagtcgg cccacatctt gacgaaagct ctgttggcca
      601 cgggcttatc agcccgaagg taaccgtcgt aaagaatgtt tgctttccga tcgagaagct
      661 gtccggcgaa ctggttgatg taggggttca tcaacgagtc gcccatgaag aaggaattat
      721 tgttgtagcg cttcgcgaga tcgctgactt gatccgcgaa ggcctgcatc ggccgcttgc
      781 gatagtcgcc ccactgaatc gtctctgagc agaagctgca ttgaaacggg caactgcgcg
      841 cgccttcgat ggtcaggtga tagtagttct ccgtgccgac atcagaaaaa tcgggaatcg
      901 gaacatcctt catttccagg gtgacgccgt ggagatccgc gagtgagatc aatcgctggc
      961 cggcaaagtc gccctggaga agtttgagca acagcagctc gccttctcca agcacgaaat
     1021 gatcgatgaa gtcgtattcg cgcacgaggg tgtcgagatt gtcggagccg agcgccaggt
     1081 cgtcggcaaa cgcgccgccg cccatgatgg ttctgatgtt cgggtgctgc tccttgactc
     1141 tcttcaggaa aaacagagac gggccaagcg atgtggtgta ggtgctggtc ccaaccgttc
     1201 cgtattccgc cagattgaat tcttcagtca gaacattcag gcgttggtaa aaattctcga
     1261 cgaggggcag cagttggcgg atgactccct gcgagatgcg catcccttga aggggaacaa
     1321 cggagctaag caccttcgca caagctgccg ggtcggcgcc attggcaaac gcgagcatgt
     1381 gcgcgttcag gatccaccag agtttcgaat agccatcgtt gatggaaacg tcctcgagtg
     1441 tctgcagcac actgaaatac ttgtggtgca tgccccagag ttcgggatcc gaattgaaat
     1501 cgtaacagcg cacctcataa ccgtgaggtt cgagaaacga cttcagaatg gcaatcccga
     1561 gcggaggcgt ccacggcgag aaataagggg gcttgaccag caggatcttg cgctccttcg
     1621 gatcgacgcc ggccagtttc cgcaaggcgt ccgaacggcc aattgacacc aaattcatga
     1681 tcgtgtcctt tccacgggta gaccgaaact gaactgatcg gtggcgaacg gcaacgtcaa
     1741 atccgccggc gactcacctg cggccgcagc ttttccatcg aggcgcagcg ggatatcgag
     1801 taaccggcta tcggggtccg caacaacggc cgtgagccat gcttcgtagt gcttcagcaa
     1861 gcgggcgatg gtctgaggct caaaaagatc gctgctgtaa gtcatcagca acgtcaaccc
     1921 ctcgcttgtc tcggtcgccc tcacgatcag atcaaactgc gtcgcttgcc agtcgacgtt
     1981 caccgcactc agctttatat cgagctcggg caacgtgagt tcacgcgcgt gctggacgcc
     2041 gaacacaacc tggaagagtg aattgctgct gagagtacgt tcgggccgca gcgcttccac
     2101 cagcttgtcg aagggcaagt cctgatgcat gtacgcgccg agcgtgactt ccttaacgcg
     2161 ttgcaacaac tctctgaaag tcgggttgcc ggaaagatcg gttcgcagca ccagcatgtt
     2221 gacgaagaat cccatgagct tctccgtctc cggatgattg cgattggcga cggtcgtacc
     2281 gacgacgatg tcttcctgcc cgctgtaacg gtgcagcaaa ctcttgaagg cggccagcat
     2341 cgtcatgaac tgcgtcgtcc cgctctcgcg gctcagtcgt ttaacttcct gcgatagttc
     2401 cggggagaac gccgcctttt gcgtcaggcc gcgcaggctc tggccttcca cccgcggtcg
     2461 atcgatcggt aactcgagag tcgacagccc gctcaatttc tccgcccagt acttgatctg
     2521 tttttcgagt acgtcactct gcatccattc ccgttgccag agggtgaagt cgccatattg
     2581 aatcgcgggc gccggcagcg gcgacggctg accgtcacgg tacgcggcat agagcgctcc
     2641 catttcctcg ataaggttat tcatggacca gccgtcggag atgatgtggt gcatcgtcac
     2701 gacgacaatg tgttcgctat ccgaaagccg cagcagtttg atccgtaaaa gcgggccggt
     2761 agagagcgtg aagggctggt tcatctcagc ctgggccatc cggatcgcag ttgcttcacg
     2821 ttcggagacg gggagatcgg ccaggtcact aacgggaagg gtgaatggtt ccgccggatt
     2881 aatgagctgt accggttgtc cgtcacgctc agggaagcag gtgcgcaacg actcgtgccg
     2941 gcggatgatc tccgtgaagc tctgctcgag cgcgctcacg ttcaatggac cagtcaagcg
     3001 catcgcgagc ggaacgttgt aggctgccgt gccggactgt aattgatcga cgaaccaaag
     3061 ccgttgttgc ccaaacgaaa gcggcaatgg ctccgccgct tcgccgcgcg cgatgatggg
     3121 tgtcacgaca cccgcgctgg cctgtatcgc agcctcaatg tgcggcgcga ggctggccac
     3181 cgttgaatat tcaaacaacg cggtcagtgg tatctggatt ttgaaagttt cgcgcacgcg
     3241 cgacatcact tgcgtggcca gtaacgaatg gccgcccacc tggaagaagt cgtcattcgc
     3301 tccgatcgag tcgaggtcca ggatggtggc aaagatatgc gtgagcagtt cttcaaccgg
     3361 cgttttcgcg ggaatgaact ccgactcact ttccggctcg gtcgttgcga gcgctgccag
     3421 cttttcgcga tcgaccttgc cgttcggagt taacggcagg tggtccagca gcacgaattg
     3481 cgacggcacc atgtactccg gcagtttctc ctgcaactgt tttcgtaact gtgcggcggc
     3541 gtcagcgccg ttgccggcgt cgccattcac cgcacaataa gcgacaagct gctggtctcc
     3601 ggtgggcgaa cgtctcacca gcacaacgct atcttcgacg ccgggctcct cgcgcaatac
     3661 tgccgcgatt tcgttcggct cgatgcgaaa gccacgaatc ttgacctggc tgtccgcgcg
     3721 cccggcaaat tcgatcgacc cgtcgctcag caagcgcact agatcaccgg tgcggtacaa
     3781 ccgctctccg gctacggaac tatgtgggtt cgggatcagg ctctcggccg tcaatgccgg
     3841 ctcattaaga tagccgcgca tcaatccgtc gccgccggcg taaagatctc cgatcacacc
     3901 gatcggtacg ggttgtaacc ttcgatcgag cacgtacgcc gtcgtgttcg taatcggctt
     3961 gccgatcgga attgtaaccg cagagtcagg cacttcgcgg accgggaacc acgagctgaa
     4021 ggttgtattc tcagttgggc catagacgtg cagcagatgt tggggcgctc cctttgcgag
     4081 cacttccctg acccattgcg gatcgaccgc ctcaccgccg aacaggagat acttaagtga
     4141 agcgaacgct tccggaatgc ggcgcgcaat ctggttgaaa agggcggtgg ttaagaacag
     4201 caccgtgagg cccaggtttt cgatttccca cgcaaactct tccggtgaga tggtaacttc
     4261 gcgccggatg atcacgagcc gcgcgccgtt cagcaggctg ccccaaattt caaacgtggc
     4321 cgcatcgaac gccgggtttg cagcttgcgc gatgcgatcg tcgctggtca gttgcacata
     4381 ctctgtatcg cgaaccagtc ggacaacgct gcgatgagta atgctcacgc ctttcggccg
     4441 gccggttgag cccgacgtgt acatcacata cgcgagattg cctggtccaa cggcagcctc
     4501 cggatcgtcc tgcgagtaac cagagagcgt ctcctccata tcgatcaggc gcaccgtttc
     4561 attagtcaca aacagttctg cgaattgttc ggttgtcagc acgagactaa cgcccgcatc
     4621 ttccagcatg agccgcagcc gcgcttccgg atagctcgca tccagcggca catagacgcc
     4681 accggccttg aggattccca gcaagccaac gatcaattcc gcgcttcgct ccaaacagat
     4741 cccgaccggc acttccgcgc tcactcccag cgatcgcaga tgatgggcca actggttggc
     4801 gcgccggttc aactcggcgt agctgagcat cgtttcacca gccacgaccg ctaccgcgtc
     4861 aggcgttgct gctgcttgcg tctcaaagag cgcgtggatg ctgtgttcac gtggatacgg
     4921 agcgttcgtc tggttccact cacacaacaa ctgattttct tctgccgccg ttagcagtcg
     4981 cagcgccgac aggcgttgat cggcatctcg gccaatgtcc gccaacaacg ttgcgagatg
     5041 ctgcaatagc cgcgtgatcg tctctgcttc gaacagctcc gtgctgtact ccagcttgaa
     5101 ccctaactcg ccttctcttt ccgtcgcggc gagaatcaga tcggatttcg cagtttcaca
     5161 ttcgcgctcc tctgccgtca gcgttacgcc cgctagctca agttccggca tcggcatgtt
     5221 tgacatcgca aacatcactt gaaacatgtg gcctacgccg cgctcgagtt ctacctcttc
     5281 cacgagcttc tcaaacggca cgtcctgatg cgcgtacgct cccagcgtca cttctcgcac
     5341 gcgacctagc aattcgcgga aagtcggatc gccactcagg tctgtgcgca gcgcgagcgt
     5401 gtttacgaag aacccgatca gtccttcgac ttcgccacgc gtccggttcg cgattccggt
     5461 ccctaccacg atgtcttcct gaccgctgac gcgcgacagc aacgtttgaa acgcggccac
     5521 tagcgtcatg aacaacgtca cgccttcgcg ccggctcaac gccttcaact ccgccaatac
     5581 ttccttgcgc acctggaggc tctgcgccgc accgcgatag gtctgcactg ccggtcgcac
     5641 gtgatccacc ggcaactcca acaccggcgc tccgtttaac tgctcgcgcc agtagctgag
     5701 ctgttgctcc agcacttcat cttgcaacca acctcgttgc cacactgcat aatccgcgta
     5761 ctgcaacggc agctcttcga gcggcgattc atttccctgg ctgtaagctt cgtaaagtgt
     5821 cccgacttct ttcaccaaca
//
