LOCUS       c00353_3300024..        3440 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300024186.a:Ga0247688_1001792.
ACCESSION   c00353_3300024..
VERSION     c00353_3300024..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 09:28:56
            Original ID  :: 3300024186.a:Ga0247688_1001792
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3440
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3440
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:3440](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(3..3440)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..3440
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3440
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             complement(3..3440)
                     /NRPS_PKS="Domain: AMP-binding (292-684). E-value:
                     1.5e-112. Score: 367.9. Matches aSDomain:
                     nrpspksdomains_ctg353_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (794-860). E-value: 1.5e-24. Score:
                     77.7. Matches aSDomain: nrpspksdomains_ctg353_1_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (872-1145). E-value:
                     6.6e-125. Score: 409.3. Matches aSDomain:
                     nrpspksdomains_ctg353_1_Epimerization.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 386;
                     E-value: 3.8e-117)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg353_1"
                     /sec_met_domain="Condensation (E-value: 8.5e-58, bitscore:
                     181.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 4.1e-124, bitscore:
                     400.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.1e-16, bitscore:
                     45.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="AAWQHEWLRGERLAAEVSYWRQQLEGAPRVLELPVARPRPAVQTL
                     AGRTESFELQAEVSRRIRQLCQQEGVTLFMLLLAAFKVLLFRYTGQQELIVGTTIAGRN
                     RKELEGLIGCFVNTLALRSKLTDRLTFRELLRQVRETTLDAYAHQDLPFEKVVEEIHPE
                     RNLSHAPLVQVMFGLALSPERQESAPDVGLTWSKLDIESVTAKFDLTLEMFDCGESLRG
                     ALEYSTDLFEQATIRRMAAHFQTLLGTIASSPSERISYLQLLTEAEREQLLGGWSNAGT
                     QDSTANCFQQLFEKQVAQSPQARALEFAGQAMSYDDLNRRANQLAHYLRELGVGPDTLV
                     AIMLERSAEMLVALVAVLKSGGAYLPLEPSYPRERLALMLEDAKAKVVLTQSHLTGLLP
                     EIGATIVCLDQCREVIEQLSEENPGRLADDDNVAYVIYTSGTTGQPKGVMVRHGGLRNL
                     VAAQLETFHIPSEDRILQFASLGFDASIFEITLALCSGATLYVSEREALLGPPLVQLLR
                     DRAITTATLPPSVLAVLPSEQLAALRTIIVAGEACPAALVAQWASGGRRFFNAYGPTEA
                     TVWATVAQCFAGSRQPPIGRPIPGAQIYLLDQSMQPAPVGVPGELFIGGEGIVRGYLGR
                     PDLTAAKFIPHPFADQPGARLYRTGDLARYLPDGQLEFLGRLDRQVKIRGFRIELGEVE
                     SVLRQHPAVQDMFLTVREDTPGRRWLVAYVVPKPETVCQVTELRSFLADRLPDHMAPSA
                     FVLLEELPLNTHGKVDQRQLPAPEPFHTKGGGEYMAPRTEVEKVLSRIWAEVLNVERVS
                     IEDNFFALGGDSILSLQLITQAHRAGLHFTPRQLFQYQTIAELATVASLRQPVSAEQGL
                     VTGAVSLTPIQHWFFEQPLLDRHHFNLAIMLEAQQTLDAKALATAMAHLLDHHDALRLR
                     FEYVEERWQQFDSAREEECVLTSFDVSRLAEEAQVKAIETTASELQRSLDLSKGPLVRM
                     ALFELGAGKANRLLWIIHHLIVDWVSWRILLEDLATAYGQLMNGEEVKLPPKTTSFKEW
                     AHKLALYAETEELASEAGYWLAHARLTSKALPVDHHAGDNTVASARTVSVSLSTDETRA
                     LLQDVSAAHGAQVNEVLLAALARSCLRWTAEGRLLVDVD"
     aSDomain        complement(6..824)
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg353_1_Epimerization.1"
                     /evalue="6.60E-125"
                     /label="ctg353_1_Epimerization.1"
                     /locus_tag="ctg353_1"
                     /protein_end="1145"
                     /protein_start="872"
                     /score="409.3"
                     /tool="antismash"
                     /translation="TGAVSLTPIQHWFFEQPLLDRHHFNLAIMLEAQQTLDAKALATAM
                     AHLLDHHDALRLRFEYVEERWQQFDSAREEECVLTSFDVSRLAEEAQVKAIETTASELQ
                     RSLDLSKGPLVRMALFELGAGKANRLLWIIHHLIVDWVSWRILLEDLATAYGQLMNGEE
                     VKLPPKTTSFKEWAHKLALYAETEELASEAGYWLAHARLTSKALPVDHHAGDNTVASAR
                     TVSVSLSTDETRALLQDVSAAHGAQVNEVLLAALARSCLRWTAEGRLLVDVD"
     aSModule        6..2564
                     /complete
                     /domains="nrpspksdomains_ctg353_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg353_1_PCP.1"
                     /domains="nrpspksdomains_ctg353_1_Epimerization.1"
                     /locus_tags="ctg353_1"
                     /monomer_pairings="X -> D-X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(372..437)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg353_1_0009"
                     /evalue="1.20E-08"
                     /label="NRPS-E2"
                     /locus_tag="ctg353_1"
                     /protein_end="1023"
                     /protein_start="1001"
                     /score="27.3"
                     /tool="antismash"
                     /translation="LLWIIHHLIVDWVSWRILLEDLA"
     CDS_motif       complement(648..722)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg353_1_0008"
                     /evalue="1.40E-05"
                     /label="C2_starter_024-063"
                     /locus_tag="ctg353_1"
                     /protein_end="931"
                     /protein_start="906"
                     /score="17.8"
                     /tool="antismash"
                     /translation="TLDAKALATAMAHLLDHHDALRLRFE"
     CDS_motif       complement(780..809)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg353_1_0007"
                     /evalue="7.20E-05"
                     /label="NRPS-E1"
                     /locus_tag="ctg353_1"
                     /protein_end="887"
                     /protein_start="877"
                     /score="15.5"
                     /tool="antismash"
                     /translation="LTPIQHWFFEQ"
     aSDomain        complement(861..1058)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg353_1_PCP.1"
                     /evalue="1.50E-24"
                     /label="ctg353_1_PCP.1"
                     /locus_tag="ctg353_1"
                     /protein_end="860"
                     /protein_start="794"
                     /score="77.7"
                     /tool="antismash"
                     /translation="EKVLSRIWAEVLNVERVSIEDNFFALGGDSILSLQLITQAHRAGL
                     HFTPRQLFQYQTIAELATVASL"
     CDS_motif       complement(1359..1424)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg353_1_0006"
                     /evalue="5.00E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg353_1"
                     /protein_end="694"
                     /protein_start="672"
                     /score="37.7"
                     /tool="antismash"
                     /translation="FLGRLDRQVKIRGFRIELGEVES"
     aSDomain        complement(1389..2564)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg353_1_AMP-binding.1"
                     /evalue="1.50E-112"
                     /label="ctg353_1_AMP-binding.1"
                     /locus_tag="ctg353_1"
                     /protein_end="684"
                     /protein_start="292"
                     /score="367.9"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FEKQVAQSPQARALEFAGQAMSYDDLNRRANQLAHYLRELGVGPD
                     TLVAIMLERSAEMLVALVAVLKSGGAYLPLEPSYPRERLALMLEDAKAKVVLTQSHLTG
                     LLPEIGATIVCLDQCREVIEQLSEENPGRLADDDNVAYVIYTSGTTGQPKGVMVRHGGL
                     RNLVAAQLETFHIPSEDRILQFASLGFDASIFEITLALCSGATLYVSEREALLGPPLVQ
                     LLRDRAITTATLPPSVLAVLPSEQLAALRTIIVAGEACPAALVAQWASGGRRFFNAYGP
                     TEATVWATVAQCFAGSRQPPIGRPIPGAQIYLLDQSMQPAPVGVPGELFIGGEGIVRGY
                     LGRPDLTAAKFIPHPFADQPGARLYRTGDLARYLPDGQLEFLGRLDRQVKIRG"
     CDS_motif       complement(1512..1601)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg353_1_0005"
                     /evalue="8.40E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg353_1"
                     /protein_end="643"
                     /protein_start="613"
                     /score="50.0"
                     /tool="antismash"
                     /translation="PVGVPGELFIGGEGIVRGYLGRPDLTAAKFI"
     CDS_motif       complement(2085..2144)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg353_1_0004"
                     /evalue="8.80E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg353_1"
                     /protein_end="452"
                     /protein_start="432"
                     /score="33.6"
                     /tool="antismash"
                     /translation="AYVIYTSGTTGQPKGVMVRHG"
     CDS_motif       complement(2340..2375)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg353_1_0003"
                     /evalue="4.90E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg353_1"
                     /protein_end="367"
                     /protein_start="355"
                     /score="13.6"
                     /tool="antismash"
                     /translation="AVLKSGGAYLPLE"
     CDS_motif       complement(2907..3026)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg353_1_0002"
                     /evalue="2.90E-25"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg353_1"
                     /protein_end="178"
                     /protein_start="138"
                     /score="80.8"
                     /tool="antismash"
                     /translation="RETTLDAYAHQDLPFEKVVEEIHPERNLSHAPLVQVMFGLA"
     CDS_motif       complement(3075..3161)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg353_1_0001"
                     /evalue="1.20E-15"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg353_1"
                     /protein_end="122"
                     /protein_start="93"
                     /score="49.8"
                     /tool="antismash"
                     /translation="LIVGTTIAGRNRKELEGLIGCFVNTLALRS"
ORIGIN
        1 ccatccacat ccacgagcaa tctgccttcc gccgtccacc tcaaacacga ccgtgctaac
       61 gcggccagca atacctcgtt gacctgcgcg ccgtgcgcgg ctgacacgtc ttgcagtaaa
      121 gcccgtgtct cgtctgtgct cagggaaacg gagaccgtac gcgcagacgc caccgtgtta
      181 tcaccggcgt ggtgatccac cggcaacgcc ttcgatgtca ggcgtgcatg ggccagccag
      241 taacccgcct cgctcgcaag ttcctccgtc tcggcataca gggccagctt gtgcgcccac
      301 tctttgaacg aagtcgtttt gggcggcagc ttgacctctt caccgttcat caactgcccg
      361 taagccgtcg ccaaatcttc caacaaaatt ctccaggaca cccagtcaac gatcaaatga
      421 tgaatgatcc acaacagacg attggctttg cccgcgccca actcaaacaa cgccatcctg
      481 acgagcggac ctttcgacaa atccaggctc ctctgtagct cactggccgt cgtttctatg
      541 gccttcacct gtgcttcttc cgctaatctt gagacgtcaa aactcgtcag gacgcactct
      601 tcctcccgcg cactatcgaa ctgctgccac ctctcttcga cgtactcaaa acgcaggcgc
      661 aacgcatcgt gatgatcgag tagatgggcc atagccgtcg ccaatgcttt cgcgtcgagc
      721 gtttgttgag cttcaagcat aatggccaga ttgaagtgat gcctgtctaa gagaggttgt
      781 tcaaagaacc aatgctggat gggcgtcagc gagactgctc cggtcaccag accttgttcc
      841 gcactgacag gctgacgcaa gctcgccacg gtcgccagtt cggcaatcgt ctgatactgg
      901 aagagctgtc tcggcgtgaa atgcaggccg gcacgatgag cctgcgttat gagttgcagg
      961 ctgagaatcg aatcaccgcc gagagcgaaa aaattatcct cgatgctcac gcgctcgacg
     1021 ttgaggacct cggcccagat tctcgacagc accttttcca cttcagtgcg cggagccatg
     1081 tactcgccgc cgccttttgt atgaaagggt tcgggcgcgg gaagctggcg ttggtctacc
     1141 ttgccgtgag tgttaagagg aagctcctcc agcagcacaa acgcggaagg cgccatgtgg
     1201 tccggcaatc tgtccgccag aaagctgcgc aactctgtta cctgacaaac tgtttccggc
     1261 ttcggaacca cgtatgcaac caaccatctg cgccccggtg tatcctcacg cactgtcagg
     1321 aacatatcct gcacggcggg gtgctgtctc agcacagact caacctctcc cagctcgatg
     1381 cgaaatcccc tgatcttgac ttggcgatca agccggccga gaaattctaa ttggccgtcg
     1441 ggcaggtaac gcgccaggtc gcctgtgcgg tacaggcgtg caccgggttg atcagcgaaa
     1501 ggatgcggga tgaatttagc agcagtcagg tcagggcgac ccaaatagcc tcgaacgatt
     1561 ccctctccac cgatgaataa ctcgccaggc acaccgacag gcgccggttg catactttgg
     1621 tctaataagt aaatttgtgc gccgggaatc ggccggccta tcggaggctg ccgggagcct
     1681 gcgaagcatt gcgcgactgt ggcccagaca gtcgcttctg tcggcccata tgcgttgaag
     1741 aagcgacgac cgccactggc ccattgcgca accagagcag caggacaagc ttccccagcg
     1801 acgatgatgg ttcgcaacgc cgccaactgt tccgacggca agaccgccag gaccgacggc
     1861 ggtagcgtcg cggtcgtgat tgcccgatca cgcaacagtt gaaccaacgg agggcctaag
     1921 agggcctcac gctccgacac gtagagcgtc gcgcctgagc agagggctaa agtgatctcg
     1981 aagatcgagg catcaaagcc gagcgaggca aactgaagga ttcgatcttc ggacggaata
     2041 tgaaatgtct caagttgggc ggccactaag ttcctcaggc caccgtgcct gaccatcacg
     2101 cctttgggct gtcccgtagt ccccgaagtg tagatcacat aagccacgtt atcgtcgtcc
     2161 gccagacggc ctgggttttc ctcgctcaac tgctcgatga cttcgcggca ttggtccaga
     2221 caaacgatcg tcgcgccgat ctccggcagc aggccggtga ggtgcgattg cgttaacacc
     2281 actttcgcct tcgcgtcctc gagcattaag gcaagacgtt ctcgcggata agagggttct
     2341 agcgggagat aggcgccacc cgacttgagg acggcaacta aggccaccag catctctgcc
     2401 gatcgctcca gcatgatggc aacgagcgtg tccggcccga cgcccaactc gcgcaagtag
     2461 tgggccaact gattcgccct gcggttcaga tcatcgtagc tcatcgcttg cccggcaaac
     2521 tccaacgctc tggcttgagg agattgcgcc acttgcttct cgaatagctg ttggaagcaa
     2581 ttagctgttg agtcttgagt tcccgcgttg ctccacccac cgagcaattg ctctctctcg
     2641 gcttcagtca acaactgcaa ataggagatg cgctctgacg gactcgacgc gatggttccg
     2701 agcaaggtct ggaagtgtgc cgccatacgt ctgatcgtcg cttgctcaaa gagatccgtg
     2761 ctgtattcaa gagcgccgcg gagactttct ccgcagtcga acatctccag cgtcagatcg
     2821 aatttcgccg tgacgctctc aatatccagt ttggaccatg tcagtcccac atccggcgca
     2881 ctctcctgcc gctcaggact gagtgccaga ccgaacatta cctggaccaa gggggcatgg
     2941 ctcagattgc gctccgggtg aatctcttcc accacctttt caaagggcag gtcctgatgc
     3001 gcgtaagcgt ccagggtcgt ctctctgact tgtctgagca attcccgaaa cgtcaggcgg
     3061 tccgtcagct tgctgcgcag ggcgagcgta ttgacgaaac atccgatcaa tccctcaagc
     3121 tcttttcggt tacgaccggc tatggtcgtg ccgacgatta gctcctgttg gcccgtgtag
     3181 cgaaataaca aaaccttgaa agctgccagc aacagcatga aaagggtgac gccctcctgc
     3241 tggcacaatt gcctgatcct tcgtgagact tcggcttgca attcaaacga ttccgttcgc
     3301 cccgcaagag tctgcacggc agggcgcggg cgcgctacgg gaagttcgag tacgcgcggc
     3361 gctccctcga gttgctgcct ccagtaagaa acctctgccg ccaatctctc tccgcgcagc
     3421 cattcgtgct gccaggcggc
//
