LOCUS       c00408_3300024..        7102 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300024186.a:Ga0247688_1000757.
ACCESSION   c00408_3300024..
VERSION     c00408_3300024..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 09:28:56
            Original ID  :: 3300024186.a:Ga0247688_1000757
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7102
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..7102
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:4684](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(2..4684)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..7102
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..7102
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             complement(2..4684)
                     /NRPS_PKS="Domain: CAL_domain (62-502). E-value: 1.1e-131.
                     Score: 431.5. Matches aSDomain:
                     nrpspksdomains_ctg408_1_CAL_domain.1"
                     /NRPS_PKS="Domain: PP-binding (615-679). E-value: 7.9e-13.
                     Score: 40.5. Matches aSDomain:
                     nrpspksdomains_ctg408_1_PP-binding.1"
                     /NRPS_PKS="Domain: Condensation_LCL (700-995). E-value:
                     1.2e-101. Score: 331.4. Matches aSDomain:
                     nrpspksdomains_ctg408_1_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1177-1560). E-value:
                     1.3e-97. Score: 318.7. Matches aSDomain:
                     nrpspksdomains_ctg408_1_AMP-binding.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     407.6; E-value: 1.3e-123)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg408_1"
                     /sec_met_domain="Condensation (E-value: 2.2e-75, bitscore:
                     240.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 7.9e-97, bitscore:
                     311.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.1e-14, bitscore:
                     40.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIEELKYNEEFLPSQTRRADVVRSSPEYSTLVDVLRHWATRKPD
                     HVSHTFLVDGENEKVSLTYAELERRAMSIAAFLQGINAAGQRVLLLDPPGLEYIAAFFG
                     CLYAGAVAVPAYPPRMNRSFSRLQEIVNDARPVAALTTASILAKADQLFEQAPELKKLS
                     WITTDNVSSQYAKHWREPHLDGSTLAFLQYTSGSTSSPKGVMVSHANLLNNQRTIRAVF
                     KQSEESIIVGWLPLYHDMGLIGNMLQPLFLGAQCILMSPVAFLQRPLRWLQAISNYRAT
                     TSGGPNFAFDLCVKRISPEDRESLDLGSWTVAFNGAEPLRANTLKRFAEVFAPCGFNPE
                     AFYPCYGLAEATLLVSGKQNSGPPIVREVSGEQLKRNRITGSDNGDRISLVSSGGSLED
                     VLIVEPETCMPCAPAAVGEVWVSGPSVAQGYWNRPDESERTFKAQLAGGGAGRFLRTGD
                     LGFINDGELFITGRLKDLMIFRGLNYYPQDIEATVERAHEQLRPLGAAFSVTVDNEERL
                     VVVQELTPRCASGFPEISEAIVQAVAEGHELQVHALWLLKAGSIPTTSSGKIRRQECRS
                     RFLANTLDSVFEWRANVPAGSYQNSNSRRLFGTVADLEAWLKTTVAERLGLDVSRVDAN
                     QRLSTYAIDSLLAVELAHTIEATTGVSLSLATFLQQVSINELAIEISARAAGSPNSISS
                     GSATAEYLPSFGQQALWFLQQLEPESSAYNIARALRFRGPLNRTALRQAFQECVNRHAV
                     LRTAFSGDGKQPVCKVREGLEASFVEQDASRWSDALLGERLSAAAQQPFNLEKDVLLRA
                     SLFERAPEEHVLLLAVHHIAADLWSMGVLFNEIVLSYEAALSGNQSILPPLALEYVDYT
                     NWQRGMLEGDEGERLWTYWQEKLGGDQPVVELPTDKPRPAVQTFQGKSHNFKLPRELTR
                     RLKALAGERGATLYMTLLAGFEVLLYHYTGQKDILVGSPVSGRSRVDFKKSVGYFVNPL
                     VMRADLSQRPSFNSFLEQVRQTTLEALVHQELPFPLLVEHLQPDRDLSRSPLFQIMFVM
                     QNMQSPGDIPLSSFALGAPGVAVTMGPLTFESVPLEQRIAQFDLTLMMAETGDELSGCF
                     EYSTDLFEAHTIERMAAHFCTLLQSIVDFPERRVSEYSLLPPAERRQLLVEWNSEQIPS
                     SSSAVCIHQLIEEQAVKTPLATALVCGAERLSYAELDQRADQLATRLRALGVGPEVRVG
                     ICLGRKTELVVALLAVLKAGGAYVPLDPGYPEERLSYMVADSGAAVVLTEAGYGERLHG
                     TASRKLYLNRAAEPVSKELSAAAVSGSNLAYVIYTSGSTGQPKGVGIEHHSAVAFLEWA
                     RRQFTDEEMAVTLAGTSICFDLSVFEIFAPLTRGGTVVLVENVLAVAADGWTNDAGLTL
                     VNTVPSALAELLRLQAVPETVRTVNLAGEALSGVLVQQLYEQSAVQSVYNLYGPTEDTT
                     YSTVQLVRAGAAPNIGRAIAQSRAYVLNEQLGLCPVGVIGELYLSGAGVARGYLGQAAR
                     TAERFMPDPYSGAAGARMYRTGDRARWLSGGELEFLGRADQ"
     aSDomain        complement(5..1153)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg408_1_AMP-binding.1"
                     /evalue="1.30E-97"
                     /label="ctg408_1_AMP-binding.1"
                     /locus_tag="ctg408_1"
                     /protein_end="1560"
                     /protein_start="1177"
                     /score="318.7"
                     /specificity="consensus: ala"
                     /tool="antismash"
                     /translation="EEQAVKTPLATALVCGAERLSYAELDQRADQLATRLRALGVGPEV
                     RVGICLGRKTELVVALLAVLKAGGAYVPLDPGYPEERLSYMVADSGAAVVLTEAGYGER
                     LHGTASRKLYLNRAAEPVSKELSAAAVSGSNLAYVIYTSGSTGQPKGVGIEHHSAVAFL
                     EWARRQFTDEEMAVTLAGTSICFDLSVFEIFAPLTRGGTVVLVENVLAVAADGWTNDAG
                     LTLVNTVPSALAELLRLQAVPETVRTVNLAGEALSGVLVQQLYEQSAVQSVYNLYGPTE
                     DTTYSTVQLVRAGAAPNIGRAIAQSRAYVLNEQLGLCPVGVIGELYLSGAGVARGYLGQ
                     AARTAERFMPDPYSGAAGARMYRTGDRARWLSGGELEFLGRADQ"
     aSModule        5..2584
                     /domains="nrpspksdomains_ctg408_1_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg408_1_AMP-binding.1"
                     /incomplete
                     /locus_tags="ctg408_1"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(110..199)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg408_1_0011"
                     /evalue="3.60E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg408_1"
                     /protein_end="1525"
                     /protein_start="1495"
                     /score="51.2"
                     /tool="antismash"
                     /translation="PVGVIGELYLSGAGVARGYLGQAARTAERFM"
     CDS_motif       complement(686..745)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg408_1_0010"
                     /evalue="4.40E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg408_1"
                     /protein_end="1333"
                     /protein_start="1313"
                     /score="31.4"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGQPKGVGIEHH"
     CDS_motif       complement(929..970)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg408_1_0009"
                     /evalue="3.10E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg408_1"
                     /protein_end="1252"
                     /protein_start="1238"
                     /score="20.1"
                     /tool="antismash"
                     /translation="LAVLKAGGAYVPLDP"
     CDS_motif       complement(1541..1660)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg408_1_0008"
                     /evalue="3.80E-22"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg408_1"
                     /protein_end="1048"
                     /protein_start="1008"
                     /score="70.8"
                     /tool="antismash"
                     /translation="RQTTLEALVHQELPFPLLVEHLQPDRDLSRSPLFQIMFVMQ"
     aSDomain        complement(1700..2584)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg408_1_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="1.20E-101"
                     /label="ctg408_1_Condensation_LCL.1"
                     /locus_tag="ctg408_1"
                     /protein_end="995"
                     /protein_start="700"
                     /score="331.4"
                     /tool="antismash"
                     /translation="YLPSFGQQALWFLQQLEPESSAYNIARALRFRGPLNRTALRQAFQ
                     ECVNRHAVLRTAFSGDGKQPVCKVREGLEASFVEQDASRWSDALLGERLSAAAQQPFNL
                     EKDVLLRASLFERAPEEHVLLLAVHHIAADLWSMGVLFNEIVLSYEAALSGNQSILPPL
                     ALEYVDYTNWQRGMLEGDEGERLWTYWQEKLGGDQPVVELPTDKPRPAVQTFQGKSHNF
                     KLPRELTRRLKALAGERGATLYMTLLAGFEVLLYHYTGQKDILVGSPVSGRSRVDFKKS
                     VGYFVNPLVMRADLS"
     CDS_motif       complement(1709..1798)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg408_1_0007"
                     /evalue="7.10E-13"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg408_1"
                     /protein_end="992"
                     /protein_start="962"
                     /score="40.9"
                     /tool="antismash"
                     /translation="DILVGSPVSGRSRVDFKKSVGYFVNPLVMRA"
     CDS_motif       complement(2144..2203)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg408_1_0006"
                     /evalue="3.10E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg408_1"
                     /protein_end="847"
                     /protein_start="827"
                     /score="26.1"
                     /tool="antismash"
                     /translation="VHHIAADLWSMGVLFNEIVLS"
     CDS_motif       complement(2294..2332)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg408_1_0005"
                     /evalue="2.60E+01"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg408_1"
                     /protein_end="797"
                     /protein_start="784"
                     /score="-2.1"
                     /tool="antismash"
                     /translation="WSDALLGERLSAAA"
     CDS_motif       complement(2411..2524)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg408_1_0004"
                     /evalue="7.40E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg408_1"
                     /protein_end="758"
                     /protein_start="720"
                     /score="53.7"
                     /tool="antismash"
                     /translation="SAYNIARALRFRGPLNRTALRQAFQECVNRHAVLRTAFS"
     aSDomain        complement(2648..2839)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg408_1_PP-binding.1"
                     /evalue="7.90E-13"
                     /label="ctg408_1_PP-binding.1"
                     /locus_tag="ctg408_1"
                     /protein_end="679"
                     /protein_start="615"
                     /score="40.5"
                     /tool="antismash"
                     /translation="WLKTTVAERLGLDVSRVDANQRLSTYAIDSLLAVELAHTIEATTG
                     VSLSLATFLQQVSINELAIE"
     aSModule        2648..4498
                     /domains="nrpspksdomains_ctg408_1_CAL_domain.1"
                     /domains="nrpspksdomains_ctg408_1_PP-binding.1"
                     /incomplete
                     /locus_tags="ctg408_1"
                     /starter_module
                     /tool="antismash"
                     /type="unknown"
     aSDomain        complement(3179..4498)
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg408_1_CAL_domain.1"
                     /evalue="1.10E-131"
                     /label="ctg408_1_CAL_domain.1"
                     /locus_tag="ctg408_1"
                     /protein_end="502"
                     /protein_start="62"
                     /score="431.5"
                     /specificity="Minowa: NH2"
                     /tool="antismash"
                     /translation="TYAELERRAMSIAAFLQGINAAGQRVLLLDPPGLEYIAAFFGCLY
                     AGAVAVPAYPPRMNRSFSRLQEIVNDARPVAALTTASILAKADQLFEQAPELKKLSWIT
                     TDNVSSQYAKHWREPHLDGSTLAFLQYTSGSTSSPKGVMVSHANLLNNQRTIRAVFKQS
                     EESIIVGWLPLYHDMGLIGNMLQPLFLGAQCILMSPVAFLQRPLRWLQAISNYRATTSG
                     GPNFAFDLCVKRISPEDRESLDLGSWTVAFNGAEPLRANTLKRFAEVFAPCGFNPEAFY
                     PCYGLAEATLLVSGKQNSGPPIVREVSGEQLKRNRITGSDNGDRISLVSSGGSLEDVLI
                     VEPETCMPCAPAAVGEVWVSGPSVAQGYWNRPDESERTFKAQLAGGGAGRFLRTGDLGF
                     INDGELFITGRLKDLMIFRGLNYYPQDIEATVERAHEQLRPL"
     CDS_motif       complement(3362..3442)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg408_1_0003"
                     /evalue="1.90E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg408_1"
                     /protein_end="441"
                     /protein_start="414"
                     /score="36.2"
                     /tool="antismash"
                     /translation="AVGEVWVSGPSVAQGYWNRPDESERTFK"
     CDS_motif       complement(4061..4120)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg408_1_0002"
                     /evalue="6.60E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg408_1"
                     /protein_end="208"
                     /protein_start="188"
                     /score="24.8"
                     /tool="antismash"
                     /translation="AFLQYTSGSTSSPKGVMVSHA"
     CDS_motif       complement(4343..4378)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg408_1_0001"
                     /evalue="1.80E-01"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg408_1"
                     /protein_end="114"
                     /protein_start="102"
                     /score="5.8"
                     /tool="antismash"
                     /translation="FGCLYAGAVAVPA"
     CDS             complement(4746..7100)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M42"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg408_2"
                     /sec_met_domain="Peptidase_M42 (E-value: 2.2e-10, bitscore:
                     27.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="KAGFRIWELVNGYLPGLLMLVSVILFALLALNQQNPPQAVAASAP
                     PEQFSSARAFSHVEVIGRAPHEIGSAEHRVVRDYIISQLTALGVVPQVQKTTAFTTRRG
                     LPEAGTVENVVARLNGTNNSRAVLLVSHYDSVPTGPGASDNGTGVASLLETLRALKSQA
                     PLKNDVIFLFTDGEEVGLLGASAFANEHPWAKDVGLVLNLEARGNTGPSIMFETSSQNG
                     WLIGELASAAPYPVGNSLSYDIYKLLPNDTDFTALRDSKLPGLNFAFIEGLTRYHTQLD
                     SVSNVDQRSLQHHGSNALALTRHFGNMNLAEKKEQNAVYFNVPGSILIHYSSFWIMPLT
                     LFVAAVFVAVIVYGLRKKQLSIGGLAMGFLACLLNIVVVAAVIFGIWFLISITTVAYSR
                     MPFGDTYNSTLYLVGFSALTIAIVATVFMLLRRKIRTENLWVGGLLWFLIMLVLSALYL
                     PGGTYLFTWPLLFGLFGLAATIALKTRASANDQNLPLRLAIVFSICALPGVILLTPLIG
                     QIFTALTVQVVFVPMIFVVLLLWSLIPLLDQLTARRRWLLSGVMLAVSFVFIGLGGLTA
                     GFDKNHPQPYHVVYGFDADSGKAVWASASGNPGKWAAQFFAAGAERAPLGKYFYKNPRP
                     FLISQAPVTPLPTPEVTLVSDKKMENGSRVLRLHITAPEQNTSVFINVSGTARTTQASL
                     NGKELKATGPNSKFEMGTDWGVRYYAPQNPGIDLDLVMESAAAVNVRLIGLSHGLPNIP
                     NTPVTNRPEYMMPAPVMLSDSTMVSRTFSFN"
ORIGIN
        1 gctggtccgc gcgcccgagg aactccagtt cgccgccact cagccaacgc gctcgatcgc
       61 ccgtgcgata catccgcgcg cccgctgcgc cgctgtaggg atcgggcata aaccgctccg
      121 ccgtgcgcgc cgcctggccc aggtaacctc gcgctactcc cgccccgctc agatacagct
      181 cgccgatcac tcccaccgga cacaatccca gttgctcatt caacacgtaa gcccggctct
      241 gcgcgatcgc tcgcccgatg ttcggcgccg cgcccgcgcg caccagttgc accgtggaat
      301 aggtagtgtc ttccgttggc ccatacaggt tatagacaga ctgcaccgcg ctctgctcgt
      361 acaactgctg caccagcacc ccgctcagcg cttcaccagc cagattcact gttcgcactg
      421 tttccggcac ggcctgcaaa cgaagcagtt ccgccaatgc tgacggcacc gtgttcacca
      481 gcgtcaaccc ggcgtcatta gtccaaccat cggccgccac ggccagcacg ttctccacca
      541 gcaccacggt cccgccgcgc gtcagcggcg caaagatctc aaacactgac aggtcgaaac
      601 agatcgacgt gcccgccagc gtcacggcca tttcttcgtc tgtaaactgg cgccgcgccc
      661 actccagaaa tgcgacggcg ctgtgatgct cgatgccgac tcctttcggt tggcccgtcg
      721 agccggacgt gtagatcaca tacgccagat ttgatccgct caccgccgcg gcactcagtt
      781 ctttactcac cggctcggcc gcccggttga gatacagctt gcggctcgct gtcccatgca
      841 gccgttcacc gtaaccagcc tcggtcagca ccaccgccgc gcccgagtcg gccaccatgt
      901 aactcaagcg ctcttccgga taacccggat ccagcggcac gtaagcgcct ccggctttca
      961 acactgccag cagcgctact accaattctg tcttccggcc caaacagatc cccacacgca
     1021 cttccggccc cacgcccaaa gctcgcaacc gcgttgccaa ctgatccgcg cgctggtcca
     1081 actccgcata actcaaccgc tccgcgccgc acaccaacgc cgtcgctagg ggcgtcttca
     1141 ccgcctgctc ttcgattaac tgatggatgc aaactgccga tgatgaagag gggatctgtt
     1201 cactgttcca ttcaacgagc aactgccggc gctcggcggg cggcaacaac gagtattcgg
     1261 aaactcgccg ctcgggaaaa tcaacgatgc tctgcagcaa ggtgcagaaa tgcgcggcca
     1321 tgcgctcaat tgtgtgggcc tcaaacaggt cggtgctgta ttcgaagcaa ccactcaatt
     1381 cgtcgccggt ctctgccatc atcaacgtca gatcaaactg cgctatacgt tgctccagcg
     1441 gcaccgactc gaaagtcaat ggacccatcg tcaccgcaac gcccggcgcg cccagggcaa
     1501 aagaagagag cgggatatcg cccggcgact gcatgttctg catgacgaac ataatctgaa
     1561 aaagtggtga gcgactaaga tcgcgatccg gctgcaggtg ttcgacgagg agcgggaacg
     1621 gcaactcctg atggaccagg gcctcgagtg tagtttgccg aacctgctcg agaaaggaat
     1681 tgaaagacgg ccgctgcgaa aggtcagcgc gcatcaccag cgggtttaca aagtagccga
     1741 ccgatttctt gaaatcgacg cgactgcgac ccgataccgg cgaacccacc agaatgtctt
     1801 tctgtccggt gtagtgataa agcaagactt caaagcccgc cagcagcgtc atgtaaagcg
     1861 tcgctccgcg ttcaccggcc agcgctttga gtcgacgcgt tagttcacgc ggcaatttga
     1921 aattgtgaga cttgccctgg aaggtctgaa ccgcgggccg cggcttgtcc gtcggcaact
     1981 ctaccaccgg ctgatcgccg cccaactttt cttgccagta ggtccagagc cgttcacctt
     2041 cgtcgccttc cagcattccg cgctgccagt ttgtgtagtc cacgtactct aaagcgaggg
     2101 gcggcaagat cgattgattg ccggagagcg ccgcttcgta actaagcacg atctcgttga
     2161 acaacactcc catggaccat agatcggcag cgatgtgatg aaccgcaagc agcagcacgt
     2221 gctcttccgg tgcgcgctcg aacaaactgg cccgcaacaa cacatccttt tcaagattga
     2281 aaggttgctg cgcggcggcg ctcaaacgct caccgagtaa agcatcgctc caacgcgaag
     2341 catcttgttc gacaaaactg gcttcgaggc cctcgcgaac tttgcagaca ggttgcttgc
     2401 cgtcgcccga gaaagcggtt cgcaaaacgg catgacggtt cacgcattcc tggaacgcct
     2461 gccgcaacgc cgtccggttt aggggtccgc gaaagcgcaa cgcacgcgcg atgttgtaag
     2521 cggaactctc gggctctaac tgctggagaa accagagggc ctgctgaccg aacgaaggca
     2581 agtactcagc cgtcgcggaa cctgacgaga ttgagttggg ggagcctgcg gcccgcgcac
     2641 ttatttcaat ggccagttcg ttgatgctga cttgttgcag gaaagtcgcg agagaaagac
     2701 taacgcccgt ggttgcttcg atggtgtggg ccaattcaac tgccagcaac gaatcgatgg
     2761 cataggtcga tagtcgttgg tttgcgtcaa cacgcgaaac gtcgagcccc aaacgctccg
     2821 ctactgtcgt tttcaaccaa gcttcgagat ccgcaacggt tccaaagagc cggcgcgaat
     2881 tcgagttctg ataactgccg gcgggcacgt tagcgcgcca ttcaaaaacc gagtccagcg
     2941 tgttggcgag aaaacgcgag cggcactcct gccggcgaat cttcccgctc gaggtcgtcg
     3001 gaatcgagcc ggctttgagc agccacagcg cgtgcacttg cagttcgtgt ccttcagcca
     3061 cggcctgcac gattgcttcg ctgatttccg gaaagcccga cgcgcaccga ggcgtcaatt
     3121 cctgaacgac tacgagccgt tcttcgttat cgaccgtcac tgagaacgcc gcgcctaaag
     3181 gccgcaactg ttcgtgcgcc ctttcaactg ttgcttcgat atcctgcgga tagtagttca
     3241 gcccacggaa gatcatcaga tctttcaggc gtccggtgat gaaaagctcg ccgtcgttga
     3301 tgaatcctaa atcgcctgtg cgcagaaaac gccccgctcc gccgccggca agctgcgcct
     3361 tgaacgtccg ctcactttcg tcaggccggt tccaatagcc ctgggccacg gatgggccag
     3421 aaacccagac ttcacccact gcggcaggtg cgcacggcat acatgtctca ggctcgacaa
     3481 tgagaacgtc ttccaaactg ccgccactgc tcaccaggct gatgcgatct ccgttgtcac
     3541 ttccggtgat gcgattcctc ttgagctgtt cgccacttac ttccctgacg atgggtggtc
     3601 ctgaattttg tttacctgaa accagcagcg tcgcctcggc aaggccgtaa cagggataga
     3661 acgcttcagg gttgaagccg caaggcgcaa atacttcggc gaagcgcttg agcgtgttgg
     3721 cacggagggg ttcggcgccg ttgaaagcta cggtccaact gccgagatcc aacgactcgc
     3781 gatcttcggg actaattctt ttgacgcaaa gatcgaaagc gaaattagga cctccactcg
     3841 tcgtcgcgcg atagttagag atcgcctgca accaacgcag cggacgttgg aggaaagcta
     3901 ccggcgacat cagtatgcac tgcgcgccga gaaataacgg ttgcagcatg ttaccgatga
     3961 ggcccatgtc gtgataaagc ggcaaccacc cgacgatgat cgactcttcg ctctgtttga
     4021 agaccgcgcg aatcgtccgc tggttgttga gcagattggc gtggctcacc atcacgccct
     4081 tgggagaaga agtcgagccg gaggtgtatt gcagaaaagc gagcgtggac ccgtcgagat
     4141 gcggttcgcg ccagtgcttt gcatattgag agctgacgtt gtcagtagtg atccaactaa
     4201 gcttcttcaa ctccggcgcc tgctcaaaga gttggtcggc tttggctaga atcgacgctg
     4261 tggtcaaagc ggcaactggc cgagcgtcat taacgatctc ttgcaagcgt gaaaacgatc
     4321 gattcatgcg cggcgggtat gcgggtaccg cgacggcccc cgcatagaga caaccgaaga
     4381 atgcggcgat gtattcgaga cccggaggat cgagaagtaa cacgcgttga ccggccgcat
     4441 taatcccttg caggaatgcc gcaatcgaca ttgcccgccg ttcaagctcg gcgtaagtca
     4501 ggctgacctt ttcattctca ccatcaacca gaaaagtgtg cgacacgtga tcgggttttc
     4561 gcgtcgccca atgccgcaac acatcgacaa gagtcgagta ttcgggagat gaacgaacga
     4621 catccgctcg tcgcgtctgc gaaggcaaga attcttcgtt gtatttgagt tcttcgattg
     4681 acatagatcg ccaacctgtc ttggcgacgg tcttcgggct agaaattgtg agaagactgc
     4741 ggagactaat taaatgagaa ggtcctggaa accatcgttg aatcactgag catgacaggc
     4801 gccggcatca tgtactcggg ccggttggtg acgggtgtat tcggaatatt cgggagccca
     4861 tgcgacaagc cgatcaagcg cacgttaacg gcagcagccg actccattac cagatccaaa
     4921 tcaatgccgg gattctgcgg cgcgtaatag cgcacgcccc agtctgttcc catctcaaac
     4981 tttgagtttg gtccggtggc tttgagttct ttgccgttta gtgaagcttg cgtagttctt
     5041 gcggttccgc tgacgttgat gaaaacggaa gtgttctgct cgggtgcggt gatatgcaac
     5101 cgcagcacgc ggctgccgtt ttccatcttc ttatcgctta ccaatgtgac ttcgggtgtc
     5161 ggcagtggtg ttactggcgc ctggctgata agaaatggac gcggattctt gtagaaatac
     5221 ttgcccaacg gcgctcgttc cgctcccgcg gcaaagaatt gggccgccca cttgccgggg
     5281 ttgccagagg cactggccca gaccgccttg ccgctatcag cgtcaaaacc atagaccacg
     5341 tgatacggct ggggatgatt cttatcgaac cctgcggtca ggccgcccaa accgatgaaa
     5401 acaaaactga cggccagcat cactcccgac aacaaccaac ggcggcgggc cgtcaattgg
     5461 tccagcaacg gaatcagcga ccagagcagt aacaccacga agatcatcgg cacgaaaacc
     5521 acttgcactg tcaaagcagt aaaaatttga ccgatcaaag gtgtcagcaa aatcacgcct
     5581 ggcagagcac aaatcgaaaa cacgatcgcc agtctcagcg gcaagttctg atcgttagcc
     5641 gaagctcgcg tctttagggc aatcgtggct gcgagtccaa acaggccgaa gagcaacggc
     5701 cacgtaaaga ggtaagtgcc tccgggcaag tagagggcgc tcagcacgag catgatcaaa
     5761 aaccacagca ggccaccaac ccagagattc tcggtcctga tctttcttcg caaaagcatg
     5821 aagacagttg ccacgatcgc gatggtcaac gcgctaaatc cgaccagata gagagtgctg
     5881 ttgtaagtat cgccaaacgg catccttgaa taagcgaccg tggtaatgct gatcaagaac
     5941 cagatgccga aaatcacggc cgccaccacc acgatgttca gcaggcaggc gaggaatccc
     6001 atggccaggc caccgatact cagttgtttt tttctcaagc cgtagacgat caccgccacg
     6061 aacacggcag cgacgaatag tgttaacggc atgatccaga agcttgaata gtgaatgagg
     6121 attgagcccg ggacgttgaa gtagacggcg ttttgttcct tcttctccgc cagattcata
     6181 ttgccgaaat ggcgggtcaa tgcgagtgca ttactgccat gatgctgaag gctgcgctgg
     6241 tccacattgc tcactgaatc gagttgcgtg tggtagcgcg tcaagccttc gataaatgcg
     6301 aagttcaggc ctggcagctt ggaatctcgc aacgccgtga agtcagtgtc gttaggcaac
     6361 agtttataga tgtcgtagga gagcgagttc ccaaccgggt aaggagcggc actggcaagc
     6421 tcacctatca gccatccatt ctggctcgac gtttcaaaca tgatcgacgg acctgtgttt
     6481 ccgcgcgctt caaggttgag cacgagcccc acatctttgg cccacggatg ctcgttagca
     6541 aacgctgagg ctcccagcag cccgacttct tctccgtccg tgaaaaggaa gattacatcg
     6601 ttcttcaacg gcgcctgtga tttcaaagcg cgcagcgttt cgagcagact ggcgacgcct
     6661 gttccgttgt cactggctcc tggtccagtc ggcacggagt cgtaatgact taccagtagc
     6721 acggcccggc tgttgttggt cccattcaac cgcgccacaa cattttccac ggtaccggct
     6781 tcgggaaggc cgcgcctggt ggtgaaggcg gttgttttct gcacctgcgg aacgacgccc
     6841 aatgcagtca actggctgat tatgtaatcg cgaaccacgc gatgctccgc ggacccaatc
     6901 tcgtgcggtg cgcgaccaat gacctccaca tgtgaaaagg cgcgagcgga tgaaaattgc
     6961 tcaggcggag cactcgctgc aactgcttgc ggcgggttct gctgattcag ggccaggagc
     7021 gcaaacagaa tcacgcttac gagcatcaag agtcccggca agtaaccatt caccaactcc
     7081 caaattcgaa agcctgcttt gg
//
