LOCUS       c00431_3300024..        5505 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300024186.a:Ga0247688_1000971.
ACCESSION   c00431_3300024..
VERSION     c00431_3300024..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 09:28:56
            Original ID  :: 3300024186.a:Ga0247688_1000971
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5505
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5505
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:5504]"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..5504
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..5505
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5505
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             2..3979
                     /NRPS_PKS="Domain: PCP (149-216). E-value: 1.9e-26. Score:
                     83.8. Matches aSDomain: nrpspksdomains_ctg431_1_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (237-539). E-value:
                     2.5e-119. Score: 389.4. Matches aSDomain:
                     nrpspksdomains_ctg431_1_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (704-1110). E-value:
                     2.8e-109. Score: 357.1. Matches aSDomain:
                     nrpspksdomains_ctg431_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1214-1280). E-value: 1.7e-24.
                     Score: 77.5. Matches aSDomain:
                     nrpspksdomains_ctg431_1_PCP.2"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     448.4; E-value: 5.4e-136)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg431_1"
                     /sec_met_domain="Condensation (E-value: 4.3e-86, bitscore:
                     275.7, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-119, bitscore:
                     386.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9e-20, bitscore:
                     58.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="PHPYSETGGERLYATGDVASWRADGRIEFVGRRDGQVKVRGFRIE
                     LAEIETVLRAHSAVEECVVLVKQSEGDEKSLVAYCANEDGELSAATLREYMKARVPDYL
                     LPSQFVTVTKMPLTPNGKIDRDALAALGTSEPEDQTSFSLPKSPAEELLASIWAKALKL
                     ERVGRDDDFFELGGHSLLATRIISRVRETFSVEVPLSVLFENPTPALMAKQVEAAVRRS
                     AGSSPPASIEPVSRDRQLPLSFAQQRLWFLNELEPGSAFYNIPVVLRLSGPLNVPVLEQ
                     TLTEVIRRHELLRTTFVTSADGTPYQHLNPATPFTLAVEDLSDLEPAERQAEAQRRASA
                     EAQKPFDLAWGPLLRVGLLRLAEDDHVAMVTLHHIISDAWSTDVFVREVATLYETYSEG
                     NESPLEELPVQYGDFAVWQRDWLSGAVLEEQLGYWRDHLGGELSVLNLPADHPRPPLQS
                     YRGAHQVLLLSAELRAKVKELCRSEGVTFYMALLAAFQVLLHRYTSQNDIVVGTPIAGR
                     NRAETEGLIGFFVNTLVMRTDLSGEPSFKEVLRRVREVSLGAYAHQDLPFEKLVEELQP
                     ERDLSRHPLFQVMFETPNPPGDLMRLSKLEMESINVDDATAKFDLTMLVAEHDDGMSVR
                     LDYCIDLFEAETITRLGRHFENLLTGLVADPSRAVGDVPFLTEDEREQLLGEWNETKTQ
                     FPHELCFQQLFAAQAERSPEATAAACAGRSWTYRELDQRTNQLARCLQENGLRAEQRVG
                     VCMERGLELLESVIAIFKAGGVYVPLDPFYPKDRLAFLTTDAEVSVLLTREASLANLPE
                     HDLPVICVDRDWDQNIATQSDGALANSTLPENLAYVIYTSGSTGKPKGAMIEHRGMLNH
                     LCAKIHDLDLSANEVVAQTASQTFDISVWQLLVPLLLGGRVEIFADEVAHHPQRLFAAA
                     TKEQVTILEVVPALLRGLLEEPDAAEASESSRLRWLIVTGEALPPGLCRQWLDLRPDVS
                     LLNAYGPTECSDDVAHFAIREPLPIEATLTPIGRPVANTRLYVADEKLRLLPIGVVGEL
                     YAAGTGVGRGYLNQPDLTAEKFLPDPFSSEPGARIYRTGDLARFNAQGNIEFLGRLDHQ
                     VKVHGFRIELGEIETALRQYEGVSEAVVMVSGGSLRAYVVAASENSLAVDELRRHLKGV
                     LPEYMIPTGFVRLETLPLTSNGKIDRRALAQLEAAETARVYVPPRTAVEEVVAAIWMEV
                     LKLERIGIHDSFFELGGHSLLSIQVLTRLQKTFHVDLPLRALFEYDTVAGISQRIVAME
                     ARPGQMEKIAEIVKRIGSMSDADKQRMLQQKRDREVAHVES"
     CDS_motif       86..151
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg431_1_0001"
                     /evalue="2.00E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg431_1"
                     /protein_end="50"
                     /protein_start="28"
                     /score="35.8"
                     /tool="antismash"
                     /translation="FVGRRDGQVKVRGFRIELAEIET"
     aSDomain        449..649
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg431_1_PCP.1"
                     /evalue="1.90E-26"
                     /label="ctg431_1_PCP.1"
                     /locus_tag="ctg431_1"
                     /protein_end="216"
                     /protein_start="149"
                     /score="83.8"
                     /tool="antismash"
                     /translation="EELLASIWAKALKLERVGRDDDFFELGGHSLLATRIISRVRETFS
                     VEVPLSVLFENPTPALMAKQVEA"
     aSModule        449..649
                     /domains="nrpspksdomains_ctg431_1_PCP.1"
                     /incomplete
                     /locus_tags="ctg431_1"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        713..1618
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg431_1_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="2.50E-119"
                     /label="ctg431_1_Condensation_LCL.1"
                     /locus_tag="ctg431_1"
                     /protein_end="539"
                     /protein_start="237"
                     /score="389.4"
                     /tool="antismash"
                     /translation="RQLPLSFAQQRLWFLNELEPGSAFYNIPVVLRLSGPLNVPVLEQT
                     LTEVIRRHELLRTTFVTSADGTPYQHLNPATPFTLAVEDLSDLEPAERQAEAQRRASAE
                     AQKPFDLAWGPLLRVGLLRLAEDDHVAMVTLHHIISDAWSTDVFVREVATLYETYSEGN
                     ESPLEELPVQYGDFAVWQRDWLSGAVLEEQLGYWRDHLGGELSVLNLPADHPRPPLQSY
                     RGAHQVLLLSAELRAKVKELCRSEGVTFYMALLAAFQVLLHRYTSQNDIVVGTPIAGRN
                     RAETEGLIGFFVNTLVMRTDLS"
     aSModule        713..3841
                     /complete
                     /domains="nrpspksdomains_ctg431_1_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg431_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg431_1_PCP.2"
                     /locus_tags="ctg431_1"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       728..760
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg431_1_0002"
                     /evalue="2.40E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="ctg431_1"
                     /protein_end="253"
                     /protein_start="242"
                     /score="10.4"
                     /tool="antismash"
                     /translation="SFAQQRLWFLNE"
     CDS_motif       779..895
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg431_1_0003"
                     /evalue="1.60E-18"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg431_1"
                     /protein_end="298"
                     /protein_start="259"
                     /score="59.0"
                     /tool="antismash"
                     /translation="AFYNIPVVLRLSGPLNVPVLEQTLTEVIRRHELLRTTFVT"
     CDS_motif       1115..1180
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg431_1_0004"
                     /evalue="4.00E-11"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg431_1"
                     /protein_end="393"
                     /protein_start="371"
                     /score="35.3"
                     /tool="antismash"
                     /translation="LHHIISDAWSTDVFVREVATLYE"
     CDS_motif       1229..1267
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg431_1_0005"
                     /evalue="2.90E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg431_1"
                     /protein_end="422"
                     /protein_start="409"
                     /score="19.7"
                     /tool="antismash"
                     /translation="QYGDFAVWQRDWLS"
     CDS_motif       1520..1609
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg431_1_0006"
                     /evalue="1.20E-18"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg431_1"
                     /protein_end="536"
                     /protein_start="506"
                     /score="59.3"
                     /tool="antismash"
                     /translation="DIVVGTPIAGRNRAETEGLIGFFVNTLVMRT"
     CDS_motif       1658..1771
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg431_1_0007"
                     /evalue="1.90E-26"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg431_1"
                     /protein_end="590"
                     /protein_start="552"
                     /score="84.6"
                     /tool="antismash"
                     /translation="REVSLGAYAHQDLPFEKLVEELQPERDLSRHPLFQVMFE"
     aSDomain        2114..3331
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg431_1_AMP-binding.1"
                     /evalue="2.80E-109"
                     /label="ctg431_1_AMP-binding.1"
                     /locus_tag="ctg431_1"
                     /protein_end="1110"
                     /protein_start="704"
                     /score="357.1"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FAAQAERSPEATAAACAGRSWTYRELDQRTNQLARCLQENGLRAE
                     QRVGVCMERGLELLESVIAIFKAGGVYVPLDPFYPKDRLAFLTTDAEVSVLLTREASLA
                     NLPEHDLPVICVDRDWDQNIATQSDGALANSTLPENLAYVIYTSGSTGKPKGAMIEHRG
                     MLNHLCAKIHDLDLSANEVVAQTASQTFDISVWQLLVPLLLGGRVEIFADEVAHHPQRL
                     FAAATKEQVTILEVVPALLRGLLEEPDAAEASESSRLRWLIVTGEALPPGLCRQWLDLR
                     PDVSLLNAYGPTECSDDVAHFAIREPLPIEATLTPIGRPVANTRLYVADEKLRLLPIGV
                     VGELYAAGTGVGRGYLNQPDLTAEKFLPDPFSSEPGARIYRTGDLARFNAQGNIEFLGR
                     LDHQVKVH"
     CDS_motif       2303..2341
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg431_1_0008"
                     /evalue="6.80E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg431_1"
                     /protein_end="780"
                     /protein_start="767"
                     /score="16.1"
                     /tool="antismash"
                     /translation="AIFKAGGVYVPLDP"
     CDS_motif       2537..2596
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg431_1_0009"
                     /evalue="8.80E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg431_1"
                     /protein_end="865"
                     /protein_start="845"
                     /score="33.6"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGKPKGAMIEHR"
     CDS_motif       3122..3211
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg431_1_0010"
                     /evalue="1.50E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg431_1"
                     /protein_end="1070"
                     /protein_start="1040"
                     /score="52.4"
                     /tool="antismash"
                     /translation="PIGVVGELYAAGTGVGRGYLNQPDLTAEKFL"
     CDS_motif       3299..3364
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg431_1_0011"
                     /evalue="1.00E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg431_1"
                     /protein_end="1121"
                     /protein_start="1099"
                     /score="36.8"
                     /tool="antismash"
                     /translation="FLGRLDHQVKVHGFRIELGEIET"
     aSDomain        3644..3841
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg431_1_PCP.2"
                     /evalue="1.70E-24"
                     /label="ctg431_1_PCP.2"
                     /locus_tag="ctg431_1"
                     /protein_end="1280"
                     /protein_start="1214"
                     /score="77.5"
                     /tool="antismash"
                     /translation="EEVVAAIWMEVLKLERIGIHDSFFELGGHSLLSIQVLTRLQKTFH
                     VDLPLRALFEYDTVAGISQRIV"
     CDS             3966..5504
                     /NRPS_PKS="Domain: Condensation_LCL (44-346). E-value:
                     2.4e-118. Score: 386.2. Matches aSDomain:
                     nrpspksdomains_ctg431_2_Condensation_LCL.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     459.1; E-value: 3.1e-139)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg431_2"
                     /sec_met_domain="Condensation (E-value: 2.1e-86, bitscore:
                     276.7, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSHEELRKKATLSADDFELLAHLLEEEGIETSAPSTITPRKRSA
                     EVELSFAQQRLWFIDQLEPGTPTYNIPFALRLNGRLDVPALERTITEIVRRHEVLRTTF
                     STAADGTPRQRVAAPGPYQLTIEDLSGMPDSDREPEALRMATLEAQAPFDLKEGPLLRV
                     KLVRLGDDDHIVLVTLHHTISDGWSTGIFMGEVANLYEAYRNGRQSSLPDLQVQYADYA
                     LWQREWLSEEVLEEQLSYWRTQLGAEQAALDLPADRPRPAVQTFRGARQKFQLAAGVKE
                     QLLKLGREEGATLFMTLLAAWQVLLHRYTGAASISTGTPIAGRTRTEIEGLIGFFVNTL
                     VLRTDVNGAESFRQLLRRVREVALGAFTHQDLPFEKLVEELHPARDASHTPLFQVWFVL
                     QNAVVGPTQFPGLTFTPVVIDSGITQFDLSLDISEAPQGMSGTLMYNVDLFNDTTISRL
                     ITHFQNLLDSIVAEPDQPVAALSLLSPYETRKLLHEWNETRATVADDRCVHELFE"
     aSDomain        4098..5003
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg431_2_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="2.40E-118"
                     /label="ctg431_2_Condensation_LCL.1"
                     /locus_tag="ctg431_2"
                     /protein_end="346"
                     /protein_start="44"
                     /score="386.2"
                     /tool="antismash"
                     /translation="AEVELSFAQQRLWFIDQLEPGTPTYNIPFALRLNGRLDVPALERT
                     ITEIVRRHEVLRTTFSTAADGTPRQRVAAPGPYQLTIEDLSGMPDSDREPEALRMATLE
                     AQAPFDLKEGPLLRVKLVRLGDDDHIVLVTLHHTISDGWSTGIFMGEVANLYEAYRNGR
                     QSSLPDLQVQYADYALWQREWLSEEVLEEQLSYWRTQLGAEQAALDLPADRPRPAVQTF
                     RGARQKFQLAAGVKEQLLKLGREEGATLFMTLLAAWQVLLHRYTGAASISTGTPIAGRT
                     RTEIEGLIGFFVNTLVLRTDVN"
     aSModule        4098..5003
                     /domains="nrpspksdomains_ctg431_2_Condensation_LCL.1"
                     /incomplete
                     /locus_tags="ctg431_2"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       4113..4142
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg431_2_0001"
                     /evalue="1.10E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="ctg431_2"
                     /protein_end="59"
                     /protein_start="49"
                     /score="11.4"
                     /tool="antismash"
                     /translation="SFAQQRLWFID"
     CDS_motif       4164..4277
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg431_2_0002"
                     /evalue="4.60E-21"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg431_2"
                     /protein_end="104"
                     /protein_start="66"
                     /score="67.2"
                     /tool="antismash"
                     /translation="PTYNIPFALRLNGRLDVPALERTITEIVRRHEVLRTTFS"
     CDS_motif       4500..4565
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg431_2_0003"
                     /evalue="4.80E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg431_2"
                     /protein_end="200"
                     /protein_start="178"
                     /score="31.9"
                     /tool="antismash"
                     /translation="LHHTISDGWSTGIFMGEVANLYE"
     CDS_motif       4614..4652
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg431_2_0004"
                     /evalue="5.60E-07"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg431_2"
                     /protein_end="229"
                     /protein_start="216"
                     /score="21.9"
                     /tool="antismash"
                     /translation="QYADYALWQREWLS"
     CDS_motif       4917..4994
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg431_2_0005"
                     /evalue="1.30E-15"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg431_2"
                     /protein_end="343"
                     /protein_start="317"
                     /score="49.6"
                     /tool="antismash"
                     /translation="GTPIAGRTRTEIEGLIGFFVNTLVLRT"
     CDS_motif       5043..5162
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg431_2_0006"
                     /evalue="5.50E-23"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg431_2"
                     /protein_end="399"
                     /protein_start="359"
                     /score="73.4"
                     /tool="antismash"
                     /translation="REVALGAFTHQDLPFEKLVEELHPARDASHTPLFQVWFVLQ"
ORIGIN
        1 gccgcacccg tacagcgaaa caggcggcga gcgcttgtat gcgacgggag acgtcgcgag
       61 ctggcgcgcg gatgggcgaa tcgaatttgt gggccggcgc gacgggcagg tgaaggtgcg
      121 cggcttccgc atcgagcttg ccgaaatcga aaccgtattg cgtgcgcatt cggcagttga
      181 agaatgtgtc gtgctcgtga agcagtcaga gggagacgag aaatccctgg tggcttactg
      241 cgcgaatgaa gacggagagc tgagtgccgc tacgttgcgc gagtacatga aggccagggt
      301 ccctgattac ctgctgccct cgcagtttgt gaccgttacc aaaatgcctc tgacgcctaa
      361 cggcaagatc gatcgcgacg ccttagccgc tctcggaacc agcgaacccg aagatcaaac
      421 cagctttagc ctgccaaaat caccggcgga agaattgctg gcgagcattt gggccaaggc
      481 gctgaagctc gaacgagtcg gacgtgatga cgacttcttc gagttaggcg gacactcgct
      541 gctggccact cgaatcattt cgcgcgttcg cgaaaccttc agcgtagagg ttccactgag
      601 tgtcttattt gagaatccga ctcccgcgct catggcgaaa caggttgaag ccgccgtgcg
      661 acgcagcgcc ggctcctccc cgccggcgtc tatcgaaccc gtttcgcgcg atcgacaact
      721 gcccttgtcg tttgctcagc aacgtctctg gttcctcaac gagttggagc cgggcagtgc
      781 tttttacaac attcccgtgg tgttgaggct gagtggacca ctcaacgtac cggtactcga
      841 acagacgctc accgaggtca ttcgccgtca cgaactgttg cgaacaacct ttgtcacgtc
      901 tgctgacggc actccttacc agcacctcaa tccagcaact ccgttcaccc tcgcggtcga
      961 agatctttcc gatctggaac cggcagagcg gcaagctgag gcccagcgcc gtgcttcagc
     1021 agaggcacag aaacctttcg atctcgcctg gggaccgttg ctgcgcgtcg gcctgttgcg
     1081 gctggcggag gacgaccatg tcgcgatggt tacgcttcat cacatcatct ccgacgcctg
     1141 gtcgacagac gtcttcgtgc gagaagtcgc aacgctttac gaaacgtaca gcgaaggaaa
     1201 cgagtctccg ctagaagaat tgccggtgca gtacggcgac tttgccgtct ggcaacggga
     1261 ttggttgagc ggggcggtac tggaagagca gttaggctac tggcgcgatc acctcggcgg
     1321 cgaactctca gttttgaact tgccggccga tcacccacgt cctccgctcc agagttaccg
     1381 gggcgcacat caggtgttgc tgctttctgc cgagctgcgc gcgaaggtga aggagttatg
     1441 ccgcagcgaa ggggtcactt tctacatggc gctattggcc gcgtttcaag tgctgctcca
     1501 tcgctacacg agccaaaacg atattgtcgt cggcactcca atcgcgggcc gcaaccgagc
     1561 agagaccgaa ggactcatcg ggttcttcgt gaacactctc gtgatgagga cagatctctc
     1621 gggcgagccg tcctttaaag aagtcttgcg ccgggtgcgg gaagtctccc ttggcgccta
     1681 cgcgcaccag gatcttccgt ttgagaagct ggtggaggaa ctacagcccg aacgcgacct
     1741 cagccgccat cctctcttcc aggtgatgtt tgaaacgccg aacccgccgg gcgatctgat
     1801 gcggttgtca aaactcgaga tggagtcgat caacgttgac gatgcgaccg caaaatttga
     1861 tttgacgatg ctggttgcgg aacacgacga cggcatgtcg gtgaggctcg attactgtat
     1921 cgacttgttc gaagcggaaa cgatcacgcg cctgggacga cactttgaaa acctgttaac
     1981 aggcctcgtt gccgatccgt cgcgtgctgt cggagacgtt ccgttcttga cggaagacga
     2041 acgagaacag ctcctcggag agtggaatga gacgaagacg cagtttccgc acgagctgtg
     2101 cttccagcaa ctcttcgcgg cgcaggccga acgttctccg gaggcgacag ccgcagcttg
     2161 cgcgggccgc agttggacct atcgcgagtt ggaccagcgc acgaaccagt tggcgcgttg
     2221 tttacaggaa aacgggttaa gagcagagca gcgcgtcggc gtctgcatgg aacgtggact
     2281 cgaactgctg gagagcgtga tcgcgatctt caaagccggc ggcgtgtacg ttccgctcga
     2341 tcccttttat ccgaaagaca gactcgcgtt tctgacgact gatgctgaag tctccgtgtt
     2401 gttaacccgc gaagcctcgc tcgcgaatct gcccgaacat gatctgcccg taatctgtgt
     2461 tgatagagac tgggaccaga acatcgccac tcagagcgat ggagcgctgg ctaacagcac
     2521 gcttcccgaa aaccttgctt atgtaatcta cacttcaggt tctactggaa aaccgaaggg
     2581 cgcgatgatc gagcatcgcg gcatgctcaa tcacctctgc gccaagattc atgatttgga
     2641 tctctccgcg aatgaggtgg tggcccaaac agcttcacaa acgtttgata tctctgtttg
     2701 gcagttgctg gttccgttac tcctgggcgg gcgggtcgag atatttgctg atgaagtcgc
     2761 gcatcatccg cagcgactct tcgccgcagc gaccaaagag caggtcacga tcctcgaggt
     2821 tgtgccggct ctgctgcgcg gactgttgga ggaaccggac gcagccgagg cgagcgagtc
     2881 atcccgcttg cgatggctga tcgtaactgg agaagcgttg ccgcccgggc tgtgtcgaca
     2941 gtggctggat cttcgtccgg acgtgtcgct gctcaatgcc tatggtccaa ccgagtgctc
     3001 ggacgacgtc gcccacttcg cgatccgtga gccgctcccg atcgaagcga ctctgacacc
     3061 gatcggacgc ccggttgcca atacgcgact ttacgtcgcg gatgaaaagc tacgactgtt
     3121 gcccattggc gtggttggtg aattgtatgc cgcgggaacc ggcgtaggac gcggatacct
     3181 taaccagccc gacctgaccg ctgagaaatt cctgcccgat ccgttttcct cagaacccgg
     3241 cgcgcgtatc taccggaccg gcgatctggc gcgcttcaat gcacagggaa acattgaatt
     3301 cctcggacgc ctggaccacc aggtgaaagt acacggcttc cggattgaac tcggcgagat
     3361 cgagacggca ttgcgacagt acgaaggcgt cagtgaagcc gtcgtgatgg taagtggcgg
     3421 atcgctccgg gcctacgtcg tcgccgccag cgaaaactcg ctcgcggtgg atgagcttcg
     3481 ccgtcacctc aaaggtgtct tgccggagta catgattccc accggcttcg tcaggctcga
     3541 gacgctgccg ctgacaagta acggaaaaat agatcgtcgt gccctggccc aactcgaggc
     3601 cgcggaaaca gctcgtgttt acgtgccgcc gcgcaccgcg gttgaagagg tggtcgccgc
     3661 gatctggatg gaagtgctca aacttgaacg catcggcatt cacgacagct tcttcgagct
     3721 tggcgggcac tcgttgctgt ccatccaggt cctgacccga ttgcagaaaa ccttccacgt
     3781 cgatttaccg ctgcgcgcgc tgttcgagta cgacacggtg gccggcatat cgcaacgcat
     3841 cgtggccatg gaagcgaggc cgggccaaat ggaaaagatc gcggaaatcg tgaagcgaat
     3901 cggcagcatg tcggacgctg acaagcagcg aatgctccag cagaagcgag accgggaggt
     3961 agcccatgtt gagtcatgaa gagttacgca aaaaggccac gctttcggct gacgatttcg
     4021 agctattggc ccacctcctc gaggaagagg gaatcgaaac cagcgctcct tcaaccatca
     4081 ctccgagaaa aaggagtgct gaagtagaac tctcgttcgc ccagcagcgg ctttggttca
     4141 tcgatcagct agaaccggga acgccgactt acaatattcc tttcgccctg cggttgaacg
     4201 gccggcttga cgtgcctgct ctcgaacgaa cgatcacgga aattgttcga cgccacgaag
     4261 ttcttcgcac caccttcagc accgccgccg acggcactcc caggcaacgc gtcgctgcgc
     4321 ctgggccgta tcagctcacg atcgaagacc tctcgggcat gcctgactcc gatcgcgaac
     4381 cggaagctct gcgaatggcc acgcttgaag cgcaggcgcc gtttgatctc aaggaaggcc
     4441 cgctactgcg agtgaaactc gtgcgtctgg gggacgacga tcacatcgtc ctggtgacct
     4501 tgcatcacac catctccgac ggctggtcca ccggaatttt catgggcgaa gttgccaacc
     4561 tttacgaagc atatcgaaac ggccggcaat catcgctgcc ggacttgcag gtgcagtatg
     4621 cggactatgc gctctggcaa agagagtggt tgagcgagga agtactcgag gagcagttga
     4681 gttactggcg tacgcaattg ggcgcagaac aggcggcgct cgatctgcct gcggatcggc
     4741 cgcggcccgc agtgcagacg tttcgcggag cgcggcaaaa attccaatta gccgcgggcg
     4801 tgaaagagca attgctgaag ctgggccgcg aggaaggagc aacgttgttc atgacgttgc
     4861 tggcggcgtg gcaagtgtta ctgcaccgtt atacgggcgc ggcgtcaata tcaaccggca
     4921 ctccgatcgc gggccgcacg cgcacggaga ttgaaggact gatcggcttc tttgtgaata
     4981 cgctcgtgct gcgtactgac gtgaacggcg ccgagagctt tcgccagttg ttgagacgcg
     5041 tgcgcgaagt cgccctcggt gcattcacgc accaggacct tccgtttgag aagctggtgg
     5101 aagaactgca cccggcccgc gacgcgagtc acacaccgct gtttcaggtt tggtttgtat
     5161 tgcaaaacgc ggtcgttggg ccaacccaat ttcccggcct caccttcacg cccgtcgtca
     5221 tcgatagcgg cattacccag tttgatctct ctctggacat ctctgaagcg ccgcagggaa
     5281 tgtccggaac gttgatgtac aacgtcgact tatttaacga caccaccatt agccggctga
     5341 tcacgcattt ccagaacctg ctggacagca tcgtggctga gccggaccag ccagtcgcgg
     5401 ctctatctct cttatcaccg tacgaaactc gcaagctttt gcacgaatgg aacgagacgc
     5461 gcgcaacagt cgctgacgat cgctgcgtcc atgaattgtt cgagg
//
