LOCUS       c00458_3300024..        3862 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300024186.a:Ga0247688_1001507.
ACCESSION   c00458_3300024..
VERSION     c00458_3300024..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 09:28:56
            Original ID  :: 3300024186.a:Ga0247688_1001507
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3862
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..3861
                     /NRPS_PKS="Domain: PCP (210-273). E-value: 8e-23. Score:
                     72.2. Matches aSDomain: nrpspksdomains_ctg458_1_PCP.1"
                     /NRPS_PKS="Domain: Condensation_DCL (307-608). E-value:
                     8.1e-69. Score: 223.7. Matches aSDomain:
                     nrpspksdomains_ctg458_1_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (768-1169). E-value: 5e-102.
                     Score: 333.2. Matches aSDomain:
                     nrpspksdomains_ctg458_1_AMP-binding.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     235.3; E-value: 2.6e-71)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg458_1"
                     /sec_met_domain="Condensation (E-value: 6.5e-56, bitscore:
                     175.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-115, bitscore:
                     372.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.3e-17, bitscore:
                     49.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="YSAHGSRIGTPLPDLSVYMLDHRMQPVPAGIRGELYVGGTGVARG
                     YLHRPELTAERFVPDPYSATAGARLYRSGDTARLLYSGALEYLGRLDSQVKVRGFRIEL
                     GEIEAALGRHESVREVAVLLREEPASDKRLTAYLVLKPTPQTRPSIEELRRFLSESLPE
                     YMLPSAFVFLERLPLTPNGKRDTSALLAIEGVRAEMAKEYVGPQTEREKELVKIWERVL
                     GLDHVGVNDNFFDLGGDSILSLQVLADARQGGISFSLQQLFRHPTVRQLAGEAAVNDGD
                     PLARPQTELFSLISEADRLKLPGGIVDAYPLARLQTGMLFHSVYHEDSVTYHNVSTLRL
                     RTHLDSSKWQLAVQQLAGRHPVLRTSFDLDRFSEPLQLVHETASIPCTIEDLRALTSEE
                     QERRLALFLEDERGRRFNWSNPPLLRFYIHRLTDETFQLSWTEHHAILDGWSVASMLTE
                     LFQTYSALLNNENSAAEPLPVVAFRDFVALEQEALKSEEFAGYWSRKLEGSTFTPLPRG
                     SSSGHLKRVPQVRSLEISLPATTYEELKHVARSASVPFKSVFLAAHLKALSFISGQADV
                     LTGLVSNGRPAEAGSERVLGLFLNTLPFRFRLSGGTWVQLMQRVFADEQELLSFRRYPL
                     SELQSLRGGQPLFETIFNFVDFHVYDNLRAREIEVLQETSFNETGFTLEANFVHERLLS
                     QVRFILKYNAVELSDEQAAAIAGYYVKSFEPISQRPHESHDSCSLLSEHESEQLVRVWN
                     QTQADYPKELCIHHLFQAQAEQSPHACAVLCDSGQLTYRELDQRANRLACYLQSLGVGP
                     EVLVGLYLERSSEMLIGLLSVLKAGGAYVPLAIEYPQERLEFMLRDSGARVLLTESKLR
                     ESLPETEAQIICVDTEWEKIAGLDQFTPADHTTPGNLAYVIYTSGSTGQPKAVAMPHRP
                     LVNLICWQLKRSAATHLRTLQFAPLSFDASFQEIFSTWWAGGTLVLIAEETRRDPVALS
                     RFLSHTQIERLFLPFVALQHLAEAAETAPQNLRQIITAGEQLKITAHIRRMFERLPQCT
                     LDNQYGPSESHVASAFMLPEDRREWMELPPIGRPIANTEMYVLDDRMQPLPSGVAGQLY
                     LGGDALARGYLNRPELTAGNFVPHPFSQKAGARLYRTGDLARHLPCGQIEFVGRSDDQV
                     KVRGFRIELGEIEAVLAQHEDVNQAVIMVVEDVPGQKRLVAYVVIRAGVALTASELRSF
                     LAAKLPNHMLPSAFVRLEKLPLTASGKVNRAALPAPESMRPALKETYAPPRNPLEERLV
                     RIW"
     protocluster    1..3862
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:3861](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..3861
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..3862
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3862
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS_motif       82..171
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg458_1_0001"
                     /evalue="1.70E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg458_1"
                     /protein_end="57"
                     /protein_start="27"
                     /score="52.3"
                     /tool="antismash"
                     /translation="PAGIRGELYVGGTGVARGYLHRPELTAERFV"
     CDS_motif       259..324
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg458_1_0002"
                     /evalue="4.00E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg458_1"
                     /protein_end="108"
                     /protein_start="86"
                     /score="38.0"
                     /tool="antismash"
                     /translation="YLGRLDSQVKVRGFRIELGEIEA"
     aSDomain        631..819
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg458_1_PCP.1"
                     /evalue="8.00E-23"
                     /label="ctg458_1_PCP.1"
                     /locus_tag="ctg458_1"
                     /protein_end="273"
                     /protein_start="210"
                     /score="72.2"
                     /tool="antismash"
                     /translation="EKELVKIWERVLGLDHVGVNDNFFDLGGDSILSLQVLADARQGGI
                     SFSLQQLFRHPTVRQLAGE"
     aSModule        631..819
                     /domains="nrpspksdomains_ctg458_1_PCP.1"
                     /incomplete
                     /locus_tags="ctg458_1"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        922..1824
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg458_1_Condensation_DCL.1"
                     /domain_subtype="Condensation_DCL"
                     /evalue="8.10E-69"
                     /label="ctg458_1_Condensation_DCL.1"
                     /locus_tag="ctg458_1"
                     /protein_end="608"
                     /protein_start="307"
                     /score="223.7"
                     /tool="antismash"
                     /translation="DAYPLARLQTGMLFHSVYHEDSVTYHNVSTLRLRTHLDSSKWQLA
                     VQQLAGRHPVLRTSFDLDRFSEPLQLVHETASIPCTIEDLRALTSEEQERRLALFLEDE
                     RGRRFNWSNPPLLRFYIHRLTDETFQLSWTEHHAILDGWSVASMLTELFQTYSALLNNE
                     NSAAEPLPVVAFRDFVALEQEALKSEEFAGYWSRKLEGSTFTPLPRGSSSGHLKRVPQV
                     RSLEISLPATTYEELKHVARSASVPFKSVFLAAHLKALSFISGQADVLTGLVSNGRPAE
                     AGSERVLGLFLNTLPFRFRLS"
     aSModule        922..3507
                     /domains="nrpspksdomains_ctg458_1_Condensation_DCL.1"
                     /domains="nrpspksdomains_ctg458_1_AMP-binding.1"
                     /incomplete
                     /locus_tags="ctg458_1"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       928..966
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg458_1_0003"
                     /evalue="4.50E-04"
                     /label="C1_dual_004-017"
                     /locus_tag="ctg458_1"
                     /protein_end="322"
                     /protein_start="309"
                     /score="13.1"
                     /tool="antismash"
                     /translation="YPLARLQTGMLFHS"
     CDS_motif       994..1101
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg458_1_0004"
                     /evalue="7.50E-09"
                     /label="C2_DCL_024-062"
                     /locus_tag="ctg458_1"
                     /protein_end="367"
                     /protein_start="331"
                     /score="27.9"
                     /tool="antismash"
                     /translation="YHNVSTLRLRTHLDSSKWQLAVQQLAGRHPVLRTSFD"
     CDS_motif       1327..1389
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg458_1_0005"
                     /evalue="2.20E-08"
                     /label="C3_DCL_135-156"
                     /locus_tag="ctg458_1"
                     /protein_end="463"
                     /protein_start="442"
                     /score="26.6"
                     /tool="antismash"
                     /translation="HHAILDGWSVASMLTELFQTYS"
     CDS_motif       1723..1815
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg458_1_0006"
                     /evalue="4.10E-10"
                     /label="C5_DCL_263-294"
                     /locus_tag="ctg458_1"
                     /protein_end="605"
                     /protein_start="574"
                     /score="32.1"
                     /tool="antismash"
                     /translation="DVLTGLVSNGRPAEAGSERVLGLFLNTLPFRF"
     CDS_motif       1876..1956
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg458_1_0007"
                     /evalue="2.70E-03"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="ctg458_1"
                     /protein_end="652"
                     /protein_start="625"
                     /score="10.0"
                     /tool="antismash"
                     /translation="ELLSFRRYPLSELQSLRGGQPLFETIFN"
     aSDomain        2305..3507
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg458_1_AMP-binding.1"
                     /evalue="5.00E-102"
                     /label="ctg458_1_AMP-binding.1"
                     /locus_tag="ctg458_1"
                     /protein_end="1169"
                     /protein_start="768"
                     /score="333.2"
                     /specificity="consensus: pro"
                     /tool="antismash"
                     /translation="FQAQAEQSPHACAVLCDSGQLTYRELDQRANRLACYLQSLGVGPE
                     VLVGLYLERSSEMLIGLLSVLKAGGAYVPLAIEYPQERLEFMLRDSGARVLLTESKLRE
                     SLPETEAQIICVDTEWEKIAGLDQFTPADHTTPGNLAYVIYTSGSTGQPKAVAMPHRPL
                     VNLICWQLKRSAATHLRTLQFAPLSFDASFQEIFSTWWAGGTLVLIAEETRRDPVALSR
                     FLSHTQIERLFLPFVALQHLAEAAETAPQNLRQIITAGEQLKITAHIRRMFERLPQCTL
                     DNQYGPSESHVASAFMLPEDRREWMELPPIGRPIANTEMYVLDDRMQPLPSGVAGQLYL
                     GGDALARGYLNRPELTAGNFVPHPFSQKAGARLYRTGDLARHLPCGQIEFVGRSDDQVK
                     VRG"
     CDS_motif       2491..2529
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg458_1_0008"
                     /evalue="1.60E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg458_1"
                     /protein_end="843"
                     /protein_start="830"
                     /score="15.0"
                     /tool="antismash"
                     /translation="LSVLKAGGAYVPLA"
     CDS_motif       2725..2784
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg458_1_0009"
                     /evalue="1.70E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg458_1"
                     /protein_end="928"
                     /protein_start="908"
                     /score="29.7"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGQPKAVAMPHR"
     CDS_motif       2899..2931
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg458_1_0010"
                     /evalue="4.10E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg458_1"
                     /protein_end="977"
                     /protein_start="966"
                     /score="-1.2"
                     /tool="antismash"
                     /translation="TWWAGGTLVLIA"
     CDS_motif       3295..3384
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg458_1_0011"
                     /evalue="2.50E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg458_1"
                     /protein_end="1128"
                     /protein_start="1098"
                     /score="45.3"
                     /tool="antismash"
                     /translation="PSGVAGQLYLGGDALARGYLNRPELTAGNFV"
     CDS_motif       3472..3537
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg458_1_0012"
                     /evalue="1.40E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg458_1"
                     /protein_end="1179"
                     /protein_start="1157"
                     /score="39.4"
                     /tool="antismash"
                     /translation="FVGRSDDQVKVRGFRIELGEIEA"
ORIGIN
        1 tacagcgccc acggcagccg tatcggaaca ccattgccgg atctgtctgt ttacatgctc
       61 gaccaccgca tgcagcctgt gcctgcagga atcaggggcg agttgtatgt cggcggtacg
      121 ggggtggcgc gtggttatct gcaccgcccg gagttgaccg ccgagagatt cgtgcctgac
      181 ccgtactccg ccaccgcggg ggcaagactc taccggagtg gcgacacggc ccggctgctc
      241 tacagcggag cgctggagta tctggggcgg ctggacagcc aagtgaaagt gcgaggcttc
      301 cgcattgagc tcggagagat cgaagctgct ctgggccggc atgagtctgt gcgcgaagtg
      361 gcggtgttgt tacgtgaaga accggcttcg gataagcgcc tgacagctta cctggtccta
      421 aagccgacgc cgcagaccag accctccatc gaggagttgc gtcgcttttt aagcgagagc
      481 ttgccggagt acatgttgcc ttctgctttc gtctttctag aaagactgcc cctcacgccc
      541 aatgggaaga gggatacaag cgcgttgctc gcaattgaag gcgttcgtgc ggagatggcg
      601 aaagaatacg tcgggccgca aaccgagagg gaaaaggagc tggtaaagat ttgggagcgc
      661 gtcctgggcc tcgatcatgt cggggttaac gataacttct ttgatctcgg cggtgattca
      721 attctctctc ttcaagtcct ggcggacgcc agacaaggtg gaattagttt ttctcttcaa
      781 caactctttc gccatccgac cgttcgtcag ttagcgggcg aagcagcggt gaacgacggc
      841 gaccctttgg cgcgacctca gaccgagctg ttcagcctta tcagtgaggc agaccgtttg
      901 aaacttccgg gcgggattgt tgacgcatac ccgctggcgc gcttgcaaac ggggatgctt
      961 tttcacagcg tctatcatga agacagcgtc acctatcata atgtgagcac tctgcggctg
     1021 cggacacatc tggacagctc gaaatggcaa ctcgccgtcc aacaactcgc cgggcgccac
     1081 ccggttctgc gcacttcgtt cgacctcgac cgtttcagcg agccgttaca attggtccac
     1141 gagacagcct ccatcccgtg cacgattgaa gatctacgcg ccttgacttc cgaggaacag
     1201 gaaaggcgcc tggcgctctt cctcgaagat gaaagaggcc gcagatttaa ttggtctaac
     1261 ccgcctttac tgcgcttcta cattcatcgt ttgaccgatg agacgttcca gttaagctgg
     1321 accgagcatc acgccattct cgacggctgg agtgtcgcct ccatgctcac cgagttattt
     1381 cagacctact cggcccttct gaataatgag aactcggccg ccgagccgct gccggtcgtc
     1441 gcctttcgcg atttcgtggc tctggagcag gaggctctca agtcggagga atttgctggt
     1501 tactggtcca ggaaattgga aggcagcacg ttcacaccat tgccacgtgg ctcttcctcc
     1561 ggccatttga agcgtgttcc acaagtccgc tctctggaaa tttctctgcc tgcaacgacc
     1621 tacgaggagt tgaagcatgt ggcccgttcg gcgtcagttc cgttcaagag tgttttcctg
     1681 gccgcgcatc tcaaggccct aagcttcatc agtggtcaag cggatgtctt gacgggtttg
     1741 gtcagtaatg gccggcctgc ggaggccggg agtgaacgtg tgcttggcct ctttctcaac
     1801 acgctgccgt ttcgttttcg attatccgga ggaacgtggg tgcagttgat gcagcgagtc
     1861 tttgcggacg aacaagaatt gttgtctttt cgtcgctacc cgctgtcgga attgcagagt
     1921 ctgcgaggag gtcaacctct gtttgagacc atattcaatt ttgtcgactt tcacgtctac
     1981 gacaatctac gtgcgcgcga gattgaggtc ttgcaagaga caagtttcaa cgagaccggc
     2041 ttcacgctcg aagccaactt cgtacatgag agactgctat ctcaagtacg attcatcctc
     2101 aaatacaacg ccgtggagtt gagcgacgaa caggccgcgg ccattgctgg ttattacgtc
     2161 aagagcttcg aacccatctc gcaacggccg cacgagtcac acgactcctg ctcgcttctc
     2221 tccgagcacg aatccgagca gttagtgaga gtttggaatc agacgcaggc agactatccg
     2281 aaagagcttt gcattcatca tctgttccag gcgcaagccg aacaatcgcc gcatgcctgc
     2341 gccgtgctct gtgactctgg gcaattgact taccgcgagt tggaccagcg agcaaaccgg
     2401 ctggcctgtt acctgcaaag tttaggagtc ggaccagagg tgctggtcgg gctttatctg
     2461 gaacgctctt cggagatgct gatcgggctg ctgagtgtcc tcaaagccgg tggggcttac
     2521 gttccgttgg ccattgagta ccctcaggaa cgattggaat ttatgctgcg agactcaggc
     2581 gcgcgcgttc tgctcactga aagcaaactc cgtgagagtc ttcctgagac agaggcgcag
     2641 atcatctgcg ttgacacgga atgggagaaa atcgccggtt tggaccaatt cactccggca
     2701 gaccacacga caccgggcaa tctcgcctat gtcatttata cctcgggatc gacaggacag
     2761 ccgaaggccg tggcaatgcc acatcggccg ctcgtcaacc ttatctgctg gcagctcaag
     2821 cgctcagccg ctactcattt gcgcacgctg caattcgctc cgctgagttt cgacgcttcg
     2881 tttcaggaaa tcttctcgac gtggtgggca ggcggaacgc tcgtgctcat cgcagaggag
     2941 actcggcgcg acccggtggc attgtcgcgg ttcctctcac acacacagat cgaaagattg
     3001 tttctgccct tcgtcgcgct gcaacatctg gccgaagctg ccgaaaccgc gccgcaaaac
     3061 ttacgtcaga tcataacggc gggcgagcag ttgaagatta cagcgcacat tcgccggatg
     3121 ttcgagagac ttccgcaatg cactttggac aatcagtatg ggccaagcga aagccatgtg
     3181 gcgagcgcct tcatgttacc cgaagaccgc cgcgagtgga tggaattacc acccatcgga
     3241 cggcccatcg ccaacaccga aatgtatgtt ctggacgaca gaatgcagcc gcttccatcg
     3301 ggagtcgccg gtcaacttta tctcggcggt gacgcactgg cgcggggcta tctgaaccgg
     3361 ccggagttga ccgccggcaa ttttgtgccc catccgttta gtcagaaagc gggagcgcgt
     3421 ctgtaccgga cgggcgacct ggcacgccac ctgccctgcg gccaaataga gtttgtcggt
     3481 cgctcggacg atcaggtcaa ggtgcgaggc ttccgcatcg agttgggcga gatagaggcc
     3541 gtgctggctc agcatgaaga cgtcaatcag gcggtgatca tggtggtgga ggatgtgccc
     3601 ggccagaaac gcctggtggc ttacgtcgtg atacgcgctg gagttgcgct cacggccagc
     3661 gagctgcgca gttttctcgc cgccaaactc ccgaaccata tgctgccttc ggcgttcgtc
     3721 aggttggaaa aattgcccct gactgcgagc ggaaaagtaa accgcgcagc gctgcccgcg
     3781 ccggagagca tgaggccggc gctcaaggag acgtatgcac cgccgcgtaa tcctttggag
     3841 gaaaggctcg ttcgtatctg gg
//
