3300025094_11 - 7 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

c00003_3300025.. (original name was: 3300025094.a:Ga0209478_1000073)

Region	Type	From	To	Most similar known cluster		Similarity
Region 3.1	phosphonate,terpene	3,453	45,120

c00008_3300025.. (original name was: 3300025094.a:Ga0209478_1000038)

Region	Type	From	To	Most similar known cluster		Similarity
Region 8.1	T3PKS	269,930	311,012

c00014_3300025.. (original name was: 3300025094.a:Ga0209478_1000040)

Region	Type	From	To	Most similar known cluster		Similarity
Region 14.1	terpene	171,790	192,821

c00017_3300025.. (original name was: 3300025094.a:Ga0209478_1000012)

Region	Type	From	To
Region 17.1	T1PKS,NRPS	51,839	104,120
Region 17.2	ladderane	178,735	219,904
Region 17.3	hglE-KS,T1PKS	297,037	350,603
Region 17.4	acyl_amino_acids	535,556	596,362

Region	Type	From	To	Similarity
Region 3.1	phosphonate,terpene	3,453	45,120
Region 8.1	T3PKS	269,930	311,012
Region 14.1	terpene	171,790	192,821
Region 17.1	T1PKS,NRPS	51,839	104,120
Region 17.2	ladderane	178,735	219,904
Region 17.3	hglE-KS,T1PKS	297,037	350,603
Region 17.4	acyl_amino_acids	535,556	596,362

No secondary metabolite regions were found in these records:: c00001_3300025.. (original name was: 3300025094.a:Ga0209478_1000154); c00002_3300025.. (original name was: 3300025094.a:Ga0209478_1000151); c00004_3300025.. (original name was: 3300025094.a:Ga0209478_1000100); c00005_3300025.. (original name was: 3300025094.a:Ga0209478_1001264); c00006_3300025.. (original name was: 3300025094.a:Ga0209478_1000272); c00007_3300025.. (original name was: 3300025094.a:Ga0209478_1001169); c00009_3300025.. (original name was: 3300025094.a:Ga0209478_1000182); c00010_3300025.. (original name was: 3300025094.a:Ga0209478_1000090); c00011_3300025.. (original name was: 3300025094.a:Ga0209478_1000281); c00012_3300025.. (original name was: 3300025094.a:Ga0209478_1000086); c00013_3300025.. (original name was: 3300025094.a:Ga0209478_1000017); c00015_3300025.. (original name was: 3300025094.a:Ga0209478_1000117); c00016_3300025.. (original name was: 3300025094.a:Ga0209478_1000426); c00018_3300025.. (original name was: 3300025094.a:Ga0209478_1000106); c00019_3300025.. (original name was: 3300025094.a:Ga0209478_1000175)

Compact view

c00003_3300025.. - Region 1 - phosphonate,terpene

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Location: 3,453 - 45,120 nt. (total: 41,668 nt) Show pHMM detection rules used

phosphonate: phosphonates
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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c00008_3300025.. - Region 1 - T3PKS

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Location: 269,930 - 311,012 nt. (total: 41,083 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

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c00014_3300025.. - Region 1 - terpene

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Location: 171,790 - 192,821 nt. (total: 21,032 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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c00017_3300025.. - Region 1 - NRPS,T1PKS

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Location: 51,839 - 104,120 nt. (total: 52,282 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 51838 - 104120:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (cys) + (gly) + (ohmal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 51838 - 95087:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (cys) + (gly) + (ohmal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 55950 - 104120:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (cys) + (gly) + (ohmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg17_71

PKS_AT (526..821): mal

ATSignature: Malonyl-CoA, inactive

Top 3 matches:: Malonyl-CoA: 91.7%; inactive: 91.7%; Propionyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 170.1
inactive: 106.2
Methoxymalonyl-CoA: 84.9
Methylmalonyl-CoA: 72.1
Propionyl-CoA: 54.9
Isobutyryl-CoA: 43.5
Ethylmalonyl-CoA: 36.5
2-Methylbutyryl-CoA: 32.6
CHC-CoA: 29.5
3-Methylbutyryl-CoA: 24.4
trans-1,2-CPDA: 22.8
Benzoyl-CoA: 20.0
Acetyl-CoA: 20.0
fatty_acid: 19.7

ctg17_72

Search NORINE for peptide: strict or relaxed

AMP-binding (785..1177): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGMIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

ctg17_74

Search NORINE for peptide: strict or relaxed

AMP-binding (255..657): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DMyNiGLIhK
Nearest Stachelhaus code:: orn
Stachelhaus code match:: 70% (weak)

c00017_3300025.. - Region 2 - ladderane

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Location: 178,735 - 219,904 nt. (total: 41,170 nt) Show pHMM detection rules used

ladderane: ladderane

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c00017_3300025.. - Region 3 - T1PKS,hglE-KS

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Location: 297,037 - 350,603 nt. (total: 53,567 nt) Show pHMM detection rules used

hglE-KS: (hglE or hglD)
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 5, location 297036 - 350603:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg17_307

PKS_AT (1254..1549): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%; inactive: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 72.4
Methoxymalonyl-CoA: 33.2
Methylmalonyl-CoA: 30.8
inactive: 30.6
CHC-CoA: 16.9
Propionyl-CoA: 16.4
Ethylmalonyl-CoA: 12.6
fatty_acid: 11.7
trans-1,2-CPDA: 10.3
Isobutyryl-CoA: 1.8
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg17_308

PKS_AT (582..885): mxmal

ATSignature: (unknown)

No matches above 50%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 33.4
Methylmalonyl-CoA: 20.6
Malonyl-CoA: 20.4
Isobutyryl-CoA: 16.9
Propionyl-CoA: 15.3
Acetyl-CoA: 12.3
3-Methylbutyryl-CoA: 9.1
fatty_acid: 5.8
CHC-CoA: 2.4
Ethylmalonyl-CoA: 0.9
trans-1,2-CPDA: 0.0
inactive: 0.0
Benzoyl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

c00017_3300025.. - Region 4 - acyl_amino_acids

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Location: 535,556 - 596,362 nt. (total: 60,807 nt) Show pHMM detection rules used

acyl_amino_acids: NasY

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