LOCUS       c00174_3300025..        3764 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300025256.a:Ga0209759_1006861.
ACCESSION   c00174_3300025..
VERSION     c00174_3300025..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 16:33:24
            Original ID  :: 3300025256.a:Ga0209759_1006861
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3764
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3764
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:3764](-)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(3..3764)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..3764
                     /SMILES="CC(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3764
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     CDS             complement(3..3764)
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (0-353). E-value:
                     8.8e-135. Score: 441.6. Matches aSDomain:
                     nrpspksdomains_ctg174_1_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (450-738). E-value: 2.9e-101.
                     Score: 330.5. Matches aSDomain:
                     nrpspksdomains_ctg174_1_PKS_AT.1"
                     /NRPS_PKS="Domain: PP-binding (852-919). E-value: 9.2e-16.
                     Score: 49.9. Matches aSDomain:
                     nrpspksdomains_ctg174_1_PP-binding.1"
                     /NRPS_PKS="type: PKS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 252.3; E-value: 1.8e-76)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg174_1"
                     /sec_met_domain="PP-binding (E-value: 1.8e-17, bitscore:
                     49.9, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 5.7e-103, bitscore:
                     330.5, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 3.8e-140, bitscore:
                     453.5, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="SPREAELMDPQQRIFLELCWECLERAGYVPDEHDVPVGVFGGMHN
                     ATYFQRHVSTRPDLVEKLGAFQVMLGNEKDYLATRVAHKLNLTGPAISMNTACSTSLVA
                     LCQAFDALRAGHCDMALAGGSSITCPPRSGYMAQEGSMLSPDGHTRSFDADAQGTVFSD
                     GAAVILLKRLSDALRDGDPIYAVVRGAAVNNDGGVKASFTAPNSAGQAAVITMALDNAG
                     VPAHTISYVETHGTATPLGDPIEIEGLTQAFHQSTNERGVCAIGSVKSNVGHLVMAAGA
                     AGVIKTALALAERRLPPSLHFRANNPKLDLGNSPFFVNDTLRAWTSNGGPLRAGVSSFG
                     VGGTNAHVVLEEPPLREPSDAANGPQLLLLSARSDAALGHAAAQLGEHLSTRPDTNLAD
                     VAFTLCKGRKVFAQRMHVVTDSVDDAAKRLRELAQLPVAKTALHPAPGVVFMFPGQGSQ
                     YAGMGRELYAAEPAFGAALDECAEILRDELGFDLRERLFADDADALRATGLTQPAIFAM
                     EYALARLWMSYGVTPVAMVGHSVGEFVAAVIAGVMSLADGARLVAKRGRLMQALPAGSM
                     LSVRMDATQLMARLAAALSLAAENAPNACVVSGETPLVQAFQAELEQAGIACRMLHTSH
                     AFHSSMMDPALASFRQAVEQIALSPPRIPIASTSTGGMLSDGEATSPDYWTQHLRSTVH
                     FSSALQSLLADPQHAFLEVGPRTTLSLLARQHPQSRGRMVLASLADMPSNERAAWLDAV
                     GQLWSCGVDVAIDRLDRRQRKHRVRLPTYPFERKRHWIDAPAAVAPLPAAAVSNVVTLP
                     LRVDLAATATPLNLIPDAPMASASPAVSSAASARATRLVAQLVALFEDVAGAEFDGVDP
                     ATHFVELGLDSLSLTQVALQLQKTFALKITFRELMESCSSFENLAQHIDRLLPPEAAAV
                     ATATEAATVAAPATPVAATSQVTVMSLPTSGGLIQDVIQQQMLIMQQQLALLAQAGAPA
                     AAPVATAPMAAASPAPVAARPAAPATDAPPDEEAALAHTTYDVKKAFGAIARIHSGSTE
                     LTRRQRVRLDAFMRRYIERTKRSKAYTQEHRPHLADPRVVNGFRPLLKEIIYQIVVERS
                     KGPKVWDLDGNEYVDALNGFGMNLFGWQPDFVLDAVRKQLDAGYEIGPQHPLAGIVAKQ
                     ICELTGFDRAALCNTGSEAVMGTVRVARTITGRDTLVIFTGSYHGIFDEVIVRGTKKLR
                     SVPAAPGILRNTSEHVLVLDYGTPESLAI"
     aSDomain        complement(1008..1208)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg174_1_PP-binding.1"
                     /evalue="9.20E-16"
                     /label="ctg174_1_PP-binding.1"
                     /locus_tag="ctg174_1"
                     /protein_end="919"
                     /protein_start="852"
                     /score="49.9"
                     /tool="antismash"
                     /translation="QLVALFEDVAGAEFDGVDPATHFVELGLDSLSLTQVALQLQKTFA
                     LKITFRELMESCSSFENLAQHID"
     aSModule        1008..3764
                     /complete
                     /domains="nrpspksdomains_ctg174_1_PKS_KS.1"
                     /domains="nrpspksdomains_ctg174_1_PKS_AT.1"
                     /domains="nrpspksdomains_ctg174_1_PP-binding.1"
                     /locus_tags="ctg174_1"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     misc_feature    complement(1365..1367)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        complement(1551..2414)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg174_1_PKS_AT.1"
                     /evalue="2.90E-101"
                     /label="ctg174_1_PKS_AT.1"
                     /locus_tag="ctg174_1"
                     /protein_end="738"
                     /protein_start="450"
                     /score="330.5"
                     /specificity="consensus: mal"
                     /specificity="Minowa: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /tool="antismash"
                     /translation="MFPGQGSQYAGMGRELYAAEPAFGAALDECAEILRDELGFDLRER
                     LFADDADALRATGLTQPAIFAMEYALARLWMSYGVTPVAMVGHSVGEFVAAVIAGVMSL
                     ADGARLVAKRGRLMQALPAGSMLSVRMDATQLMARLAAALSLAAENAPNACVVSGETPL
                     VQAFQAELEQAGIACRMLHTSHAFHSSMMDPALASFRQAVEQIALSPPRIPIASTSTGG
                     MLSDGEATSPDYWTQHLRSTVHFSSALQSLLADPQHAFLEVGPRTTLSLLARQHPQSRG
                     RMVLASLA"
     CDS_motif       complement(1680..1715)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg174_1_0009"
                     /evalue="2.10E-03"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="ctg174_1"
                     /protein_end="695"
                     /protein_start="683"
                     /score="11.6"
                     /tool="antismash"
                     /translation="YWTQHLRSTVHFS"
     CDS_motif       complement(1938..1976)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg174_1_0008"
                     /evalue="3.10E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="ctg174_1"
                     /protein_end="609"
                     /protein_start="596"
                     /score="10.9"
                     /tool="antismash"
                     /translation="AAENAPNACVVSGE"
     CDS_motif       complement(2058..2180)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg174_1_0007"
                     /evalue="4.60E-24"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ctg174_1"
                     /protein_end="569"
                     /protein_start="528"
                     /score="76.7"
                     /tool="antismash"
                     /translation="GVTPVAMVGHSVGEFVAAVIAGVMSLADGARLVAKRGRLMQA"
     CDS_motif       complement(2184..2237)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg174_1_0006"
                     /evalue="9.90E-05"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="ctg174_1"
                     /protein_end="527"
                     /protein_start="509"
                     /score="15.4"
                     /tool="antismash"
                     /translation="TQPAIFAMEYALARLWMSY"
     CDS_motif       complement(2364..2420)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg174_1_0005"
                     /evalue="2.70E-08"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="ctg174_1"
                     /protein_end="467"
                     /protein_start="448"
                     /score="25.7"
                     /tool="antismash"
                     /translation="VFMFPGQGSQYAGMGRELYA"
     CDS_motif       complement(2664..2684)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg174_1_0004"
                     /evalue="2.90E+01"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="ctg174_1"
                     /protein_end="367"
                     /protein_start="360"
                     /score="-1.2"
                     /tool="antismash"
                     /translation="AANGPQLL"
     aSDomain        complement(2706..3764)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg174_1_PKS_KS.1"
                     /evalue="8.80E-135"
                     /label="ctg174_1_PKS_KS.1"
                     /locus_tag="ctg174_1"
                     /protein_end="353"
                     /protein_start="0"
                     /score="441.6"
                     /tool="antismash"
                     /translation="SPREAELMDPQQRIFLELCWECLERAGYVPDEHDVPVGVFGGMHN
                     ATYFQRHVSTRPDLVEKLGAFQVMLGNEKDYLATRVAHKLNLTGPAISMNTACSTSLVA
                     LCQAFDALRAGHCDMALAGGSSITCPPRSGYMAQEGSMLSPDGHTRSFDADAQGTVFSD
                     GAAVILLKRLSDALRDGDPIYAVVRGAAVNNDGGVKASFTAPNSAGQAAVITMALDNAG
                     VPAHTISYVETHGTATPLGDPIEIEGLTQAFHQSTNERGVCAIGSVKSNVGHLVMAAGA
                     AGVIKTALALAERRLPPSLHFRANNPKLDLGNSPFFVNDTLRAWTSNGGPLRAGVSSFG
                     VGGTNAHVVLEEPP"
     CDS_motif       complement(2925..2969)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg174_1_0003"
                     /evalue="7.70E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="ctg174_1"
                     /protein_end="280"
                     /protein_start="265"
                     /score="9.2"
                     /tool="antismash"
                     /translation="GSVKSNVGHLVMAAGA"
     CDS_motif       complement(3030..3077)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg174_1_0002"
                     /evalue="1.30E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="ctg174_1"
                     /protein_end="245"
                     /protein_start="229"
                     /score="11.2"
                     /tool="antismash"
                     /translation="YVETHGTATPLGDPIEI"
     CDS_motif       complement(3453..3500)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg174_1_0001"
                     /evalue="8.60E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="ctg174_1"
                     /protein_end="104"
                     /protein_start="88"
                     /score="14.9"
                     /tool="antismash"
                     /translation="GPAISMNTACSTSLVAL"
ORIGIN
        1 atgatcgcca gcgattcggg cgtgccgtaa tccagcacca gcacatgttc ggaggtgttg
       61 cgcaggatgc ccggcgcggc tggaaccgaa cgcagtttct tggtgccgcg cacgatcact
      121 tcatcgaaga tgccgtgata cgagccggta aagatcacca gcgtatcgcg gccggtgatg
      181 gtgcgcgcca cgcgcaccgt gcccatcacc gcttcggagc cggtgttgca caaggcggcg
      241 cgatcgaaac cggtgagctc gcagatctgc ttggcgacga tgccggcaag cgggtgttgc
      301 ggaccgatct catagccggc gtcgagctgc ttgcgcacgg catccagcac gaagtccggt
      361 tgccagccaa acaggttcat gccgaaaccg ttcagcgcat cgacgtattc gttgccatcc
      421 aggtcccaca ctttcgggcc cttggagcgc tcgaccacga tctggtagat gatttccttc
      481 agcagtggcc ggaagccgtt gaccacgcgc ggatcggcca ggtgcgggcg atgttcctgc
      541 gtataggctt tcgatcgttt cgtgcgttcg atgtagcggc gcatgaaggc atccaggcgt
      601 acgcgctggc ggcgggtcag ctcggtcgag ccggaatgga tacgcgcgat tgcgccgaac
      661 gccttcttga cgtcgtaggt ggtgtgcgcc agcgcggctt cttcgtctgg cggcgcatcg
      721 gttgcgggtg ctgccggtct tgccgcaacg ggcgcgggcg atgctgctgc catcggcgcg
      781 gttgcgacag gtgccgctgc gggtgcgcct gcctgggcaa gcagcgccag ctgctgttgc
      841 atgatcagca tttgctgctg gatcacgtcc tggatcaatc caccgcttgt cggtagggac
      901 ataaccgtta cctggctggt tgccgcgact ggagtggccg gcgccgcgac ggtcgctgct
      961 tcggtcgcgg tagcgactgc ggcagcttcg ggcggcagca gccggtcgat atgttgggcg
     1021 aggttttcga acgaggaaca ggattccatc agctcgcgga aggtgatctt cagcgcgaag
     1081 gtcttttgca gttgcagggc cacctgggtc agcgacagcg aatccaggcc cagttcgacg
     1141 aaatgcgtgg ccggatccac gccgtcgaat tcggcaccgg caacgtcttc gaacaaggcg
     1201 acgagttgcg cgaccaggcg cgtggcgcgc gcggatgcgg cggatgagac ggcaggcgag
     1261 gcagaggcca tgggtgcgtc cggaatgaga ttgaggggtg tggctgttgc ggcgagatca
     1321 acgcgcagcg gaagcgtgac gacgttggat accgctgccg ccggtaatgg agcgacagcc
     1381 gctggcgcat cgatccagtg acgcttgcgt tcgaacggat aggtcggcag gcgcacgcga
     1441 tgcttgcgtt gccgccgatc caatcgatcg atggcaacgt cgacgccgca cgaccacagt
     1501 tgtccgaccg catcgagcca cgcggcgcgt tcgttcgatg gcatgtcggc cagcgacgcc
     1561 agcaccatcc ggccacggct ttgtggatgc tgccgcgcca gcaggctgag cgtcgtgcgc
     1621 ggtcccactt ccaggaaggc atgctgcgga tcggccagca ggctttgcag tgcgctggaa
     1681 aaatgcacgg tgctgcgcag gtgctgcgtc cagtaatccg gggatgtcgc ttcgccgtcg
     1741 ctcagcatgc cgccggtcga tgtcgaggca atgggaatgc gcggcggcga cagtgcgatc
     1801 tgttcgaccg cctgccggaa cgaggccaag gccggatcca tcatggaaga atggaaagcg
     1861 tgggacgtat gcaacatccg gcaagcgatg ccggcttgtt ccagttccgc ctggaatgcc
     1921 tgcaccagtg gcgtttcgcc ggacaccacg caggcgttcg gtgcgttttc ggcagcgagc
     1981 gatagcgcag ccgcaagccg cgccatcagt tgcgtggcgt ccatgcgcac cgacaacatc
     2041 gaaccggccg gcagcgcctg catcaggcga ccgcgcttgg cgaccaggcg ggcaccatcg
     2101 gcaagactca tcacaccggc gatcactgcc gccacgaatt cgcccacgct atggccgacc
     2161 atggcgacgg gcgtcacgcc gtagctcatc cacagccggg ccagcgcata ttccattgcg
     2221 aagatcgccg gctgggtgag tccggtggcg cgcagggcat ccgcatcgtc ggcaaacagc
     2281 cgttcgcgca ggtcgaagcc gagttcgtcg cgaagtattt cggcgcattc gtcgagcgct
     2341 gcgccgaatg ccggttccgc ggcgtacagc tcgcgtccca tgccggcgta ttgcgaaccc
     2401 tggccgggga acatgaagac gacgccaggc gccggatgca gcgcggtctt cgcgaccggc
     2461 aactgcgcca gttcgcgcaa gcgtttcgcg gcatcgtcga cgctgtcggt aaccacgtgc
     2521 atgcgttgcg cgaaaacctt tcgtcctttg cacagcgtga aggccacgtc ggcgaggttg
     2581 gtgtccggtc gcgtggaaag atgctcgccc aattgcgccg ccgcatggcc gagcgccgca
     2641 tcgctgcgcg cggaaagcag caagagctga ggaccgttgg cagcatcgga aggctcgcgc
     2701 agcggtggct cttccagcac cacatgcgcg ttggtgccgc cgacgccgaa cgagctgacg
     2761 ccggcgcgca gcggaccgcc gttcgatgtc cacgcccgca aggtatcgtt gacgaagaac
     2821 ggcgagttgc cgagatcgag cttcgggttg ttggcacgga agtgcagtga cggtggcaag
     2881 cgccgttcgg ccagcgccaa cgcggtcttg atcacgccgg ccgcgccggc cgccatcacc
     2941 agatggccca cgttgctctt gaccgaaccg atcgcgcaga cgccgcgttc gttcgtgctc
     3001 tggtggaatg cctgggtcag tccttcgatt tcgattggat cgcccaacgg cgtggccgta
     3061 ccgtgggttt ccacgtagga aatcgtatgg gccggcaccc cggcgttatc cagcgccatg
     3121 gtgatcacgg ccgcttgccc ggcgctgttc ggcgcggtga agctcgcctt gacgccgcca
     3181 tcgttgttga ccgccgcacc gcgaacgacg gcgtagatcg gatcgccgtc gcgcaaggca
     3241 tcggaaagcc gtttcaacaa aatgacggcg gcgccatcgc tgaataccgt gccctgcgca
     3301 tcggcgtcga aactgcgcgt gtgcccgtcg ggcgacagca tcgagccttc ctgcgccatg
     3361 taaccgctgc gcggcggaca ggtgatcgac gagccgccgg ccagcgccat gtcgcaatgg
     3421 cccgcgcgca aggcatcgaa ggcctggcag agcgccacca gcgaggtgga gcatgcggtg
     3481 ttcatgctga tcgccgggcc ggtgaggttg agcttgtgcg cgacgcgcgt ggccagatag
     3541 tccttttcgt tgcccaacat cacttggaag gcgccgagct tttcgaccag gtccggccgc
     3601 gtgctgacgt ggcgctggaa atacgtggcg ttgtgcatgc cgccgaacac gcccaccggc
     3661 acgtcatgtt cgtccggcac gtagccggcg cgctccaggc actcccagca cagttccagg
     3721 aagatccgct gttgcggatc catcagctcc gcttcgcgcg gcga
//
