3300025272_10 - 8 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

c00005_3300025.. (original name was: 3300025272.a:Ga0209455_1000079)

Region	Type	From	To	Most similar known cluster		Similarity
Region 5.1	arylpolyene	1	39,564

c00006_3300025.. (original name was: 3300025272.a:Ga0209455_1000056)

Region	Type	From	To	Most similar known cluster		Similarity
Region 6.1	bacteriocin	341,594	349,821

c00010_3300025.. (original name was: 3300025272.a:Ga0209455_1000054)

Region	Type	From	To	Most similar known cluster		Similarity
Region 10.1	bacteriocin	241,607	252,449

c00012_3300025.. (original name was: 3300025272.a:Ga0209455_1000082)

Region	Type	From	To	Most similar known cluster		Similarity
Region 12.1	terpene	1	18,894

c00014_3300025.. (original name was: 3300025272.a:Ga0209455_1000027)

Region	Type	From	To	Most similar known cluster		Similarity
Region 14.1	terpene	437,206	460,336
Region 14.2	bacteriocin	527,462	538,268

c00015_3300025.. (original name was: 3300025272.a:Ga0209455_1000020)

Region	Type	From	To	Most similar known cluster		Similarity
Region 15.1	NRPS,T1PKS	317,849	375,521
Region 15.2	NRPS	651,176	702,259

Region	Type	From	To	Similarity
Region 5.1	arylpolyene	1	39,564
Region 6.1	bacteriocin	341,594	349,821
Region 10.1	bacteriocin	241,607	252,449
Region 12.1	terpene	1	18,894
Region 14.1	terpene	437,206	460,336
Region 14.2	bacteriocin	527,462	538,268
Region 15.1	NRPS,T1PKS	317,849	375,521
Region 15.2	NRPS	651,176	702,259

No secondary metabolite regions were found in these records:: c00001_3300025.. (original name was: 3300025272.a:Ga0209455_1000039); c00002_3300025.. (original name was: 3300025272.a:Ga0209455_1000071); c00003_3300025.. (original name was: 3300025272.a:Ga0209455_1000163); c00004_3300025.. (original name was: 3300025272.a:Ga0209455_1000355); c00007_3300025.. (original name was: 3300025272.a:Ga0209455_1000019); c00008_3300025.. (original name was: 3300025272.a:Ga0209455_1001041); c00009_3300025.. (original name was: 3300025272.a:Ga0209455_1000501); c00011_3300025.. (original name was: 3300025272.a:Ga0209455_1000120); c00013_3300025.. (original name was: 3300025272.a:Ga0209455_1000533); c00016_3300025.. (original name was: 3300025272.a:Ga0209455_1000086); c00017_3300025.. (original name was: 3300025272.a:Ga0209455_1000155); c00018_3300025.. (original name was: 3300025272.a:Ga0209455_1000270); c00019_3300025.. (original name was: 3300025272.a:Ga0209455_1000164); c00020_3300025.. (original name was: 3300025272.a:Ga0209455_1000348); c00021_3300025.. (original name was: 3300025272.a:Ga0209455_1001751)

Compact view

c00005_3300025.. - Region 1 - arylpolyene

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Location: 1 - 39,564 nt. (total: 39,564 nt) Show pHMM detection rules used

Region on contig edge.

arylpolyene: (APE_KS1 or APE_KS2)

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c00006_3300025.. - Region 1 - bacteriocin

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Location: 341,594 - 349,821 nt. (total: 8,228 nt) Show pHMM detection rules used

Region on contig edge.

bacteriocin: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or TIGR01193)

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core biosynthetic genes

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c00010_3300025.. - Region 1 - bacteriocin

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Location: 241,607 - 252,449 nt. (total: 10,843 nt) Show pHMM detection rules used

bacteriocin: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or TIGR01193)

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core biosynthetic genes

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TTA codons

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c00012_3300025.. - Region 1 - terpene

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Location: 1 - 18,894 nt. (total: 18,894 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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c00014_3300025.. - Region 1 - terpene

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Location: 437,206 - 460,336 nt. (total: 23,131 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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core biosynthetic genes

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c00014_3300025.. - Region 2 - bacteriocin

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Location: 527,462 - 538,268 nt. (total: 10,807 nt) Show pHMM detection rules used

bacteriocin: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or TIGR01193)

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core biosynthetic genes

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c00015_3300025.. - Region 1 - NRPS,T1PKS

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Location: 317,849 - 375,521 nt. (total: 57,673 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 317848 - 375521:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (val - mal) + (gly - gly)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg15_290

Search NORINE for peptide: strict or relaxed

AMP-binding (117..314): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: Drp-iAtLIK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 50% (weak)

ctg15_294

Search NORINE for peptide: strict or relaxed

AMP-binding (491..888): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQiGaVWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 80% (moderate)

AMP-binding (1549..1944): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGmVWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 90% (moderate)

ctg15_295

Search NORINE for peptide: strict or relaxed

AMP-binding (215..608): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DALWLGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 100% (strong)

PKS_AT (1328..1617): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 83.3%; Methylmalonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 153.7
inactive: 82.2
Methylmalonyl-CoA: 63.7
Methoxymalonyl-CoA: 60.8
Propionyl-CoA: 46.8
Acetyl-CoA: 29.9
Isobutyryl-CoA: 26.5
Benzoyl-CoA: 24.9
CHC-CoA: 24.2
Ethylmalonyl-CoA: 23.5
2-Methylbutyryl-CoA: 23.2
fatty_acid: 18.0
trans-1,2-CPDA: 15.6
3-Methylbutyryl-CoA: 10.3

c00015_3300025.. - Region 2 - NRPS

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Location: 651,176 - 702,259 nt. (total: 51,084 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 651175 - 702259:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X) + (asp) + (val)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg15_561

Search NORINE for peptide: strict or relaxed

AMP-binding (473..875): X

NRPSPredictor2: tyr, bht

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: tyr, bht
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DvSviGAICK
Nearest Stachelhaus code:: bht
Stachelhaus code match:: 70% (weak)

ctg15_562

Search NORINE for peptide: strict or relaxed

AMP-binding (496..899): asp

NRPSPredictor2: asp

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asp

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKVaHVaK
Nearest Stachelhaus code:: asp
Stachelhaus code match:: 80% (moderate)

ctg15_564

Search NORINE for peptide: strict or relaxed

AMP-binding (36..428): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DgflLGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 70% (weak)