LOCUS       c00343_3300025..        9512 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300025284.a:Ga0209130_1002384.
ACCESSION   c00343_3300025..
VERSION     c00343_3300025..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 08:19:25
            Original ID  :: 3300025284.a:Ga0209130_1002384
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9512
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9512
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2113:4192](-)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(2114..4192)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..9512
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9512
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             complement(3..269)
                     /locus_tag="ctg343_1"
                     /transl_table=11
                     /translation="MRKKVTRSEPGRTGFAGRLRRDARAAANCTRRRLGDAGMQARDTP
                     PWVLIHCFAAVAGRRHLGGSKLMRRLTDRTEARLAPGAATGRAG"
     CDS             complement(735..2012)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 147.5; E-value:
                     9.1e-45)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg343_2"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 9.5e-29, bitscore:
                     89.7, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENGPMQSFQNVAPPRLGFGGLDAELTDEERDVQRKIQSFALDVM
                     RPTAAKLDPMAAVDVIGEGSPLWEYLSRFDELGINPTWLATLSPQRLKRMLPLVFEELA
                     YGDAGLAVAAFTSKMARGVAAATGDPELIERFSPLRGCWIATLTDRGSDAIDHVGFELA
                     KGTRQREGSLRAMMRGSEVILNGVSSDWISCAPIAECALIHCPADYGGGIARPDGGVSG
                     IALLVPFDLPGIERGRPVEKIGQRTLPTGNVRFSDVRVPARYIIRGQDAFYASIAGTHA
                     SGAMNVAAIATGVAKAALDCALHYAQSREQGGVKLVAHQHVRWRLWEMWRKLELCRASV
                     RRGVTYNLSPEGPHLLASITAKTTTTQTAFEVAMEAIQIFGANGLSRDHVVERLLRDIT
                     VCLIQGGENHYLGLQGGNWLLHSLNS"
     CDS             complement(2114..4192)
                     /NRPS_PKS="Domain: CAL_domain (44-486). E-value: 2.7e-125.
                     Score: 410.3. Matches aSDomain:
                     nrpspksdomains_ctg343_3_CAL_domain.1"
                     /NRPS_PKS="Domain: ACP (616-667). E-value: 6.5e-15. Score:
                     47.0. Matches aSDomain: nrpspksdomains_ctg343_3_ACP.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     371.4; E-value: 9.9e-113)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg343_3"
                     /sec_met_domain="AMP-binding (E-value: 8.4e-90, bitscore:
                     290.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6.4e-12, bitscore:
                     35.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATDPLAKADDRCFSDILARRAEAHPAKDALVVVGADGAEKLRLT
                     YGELGAQVERYAAGLIERGLAGQRALMLFEPGAGFIVAFMACLRAGVTAVPCHLAKPGR
                     STWDRLVAIVRDAGAVAILSEEASIPKLTGWFVDSPELSLLPMLSPGDLDADPSDIDWQ
                     RPPADEPAFLQYTSGSTGVPKGNVVTFGNLIANASVVGVGCGFDFDATIVCWLPPYHDL
                     GLIGNILQSLLDGALCVLLPPVSVIQNPRRWLETISRYRATISMAPNFAYDLCVRRIPT
                     DRQNALDLSSWRCALNAAEPIRAATMSAFAEAYRDCGFREEAFQPAYGLAEATLMISVA
                     DLDRLPATLSVDAAALDTGRIVPADGPRSRRIAGSGKVRRPQRVTIVDPASRQVCEEGV
                     VGEIWVSGPCVAHGYWRRPDASAQTFGTRLADGQGPFLRTGDLGIVIDDELYITGRIKE
                     VMIVRGRNIYPQDIEASVQRAHDALKPAGGAVFSIDREDGEAIVVVQEIERSWLATANR
                     EDLIARIRDAVFQEHELTVAEVVLTKPETVPKTSAGKIQRVLCRDLYRRGKLEQAIQGR
                     STRIAPIAVTAADATVPADGVSAIPALIARWAAGRGIRPPEAGQTFAEAGFDSISAVEL
                     THFLETELGLELDQTLLWTCTTVETLSRHLAALQAPGAPGGAKVAAPAQAIAESAGW"
     aSDomain        complement(2192..2344)
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg343_3_ACP.1"
                     /evalue="6.50E-15"
                     /label="ctg343_3_ACP.1"
                     /locus_tag="ctg343_3"
                     /protein_end="667"
                     /protein_start="616"
                     /score="47.0"
                     /tool="antismash"
                     /translation="EAGQTFAEAGFDSISAVELTHFLETELGLELDQTLLWTCTTVETL
                     SRHLAAL"
     aSModule        2192..4060
                     /domains="nrpspksdomains_ctg343_3_CAL_domain.1"
                     /domains="nrpspksdomains_ctg343_3_ACP.1"
                     /incomplete
                     /locus_tags="ctg343_3"
                     /starter_module
                     /tool="antismash"
                     /type="unknown"
     aSDomain        complement(2735..4060)
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg343_3_CAL_domain.1"
                     /evalue="2.70E-125"
                     /label="ctg343_3_CAL_domain.1"
                     /locus_tag="ctg343_3"
                     /protein_end="486"
                     /protein_start="44"
                     /score="410.3"
                     /specificity="Minowa: NH2"
                     /tool="antismash"
                     /translation="TYGELGAQVERYAAGLIERGLAGQRALMLFEPGAGFIVAFMACLR
                     AGVTAVPCHLAKPGRSTWDRLVAIVRDAGAVAILSEEASIPKLTGWFVDSPELSLLPML
                     SPGDLDADPSDIDWQRPPADEPAFLQYTSGSTGVPKGNVVTFGNLIANASVVGVGCGFD
                     FDATIVCWLPPYHDLGLIGNILQSLLDGALCVLLPPVSVIQNPRRWLETISRYRATISM
                     APNFAYDLCVRRIPTDRQNALDLSSWRCALNAAEPIRAATMSAFAEAYRDCGFREEAFQ
                     PAYGLAEATLMISVADLDRLPATLSVDAAALDTGRIVPADGPRSRRIAGSGKVRRPQRV
                     TIVDPASRQVCEEGVVGEIWVSGPCVAHGYWRRPDASAQTFGTRLADGQGPFLRTGDLG
                     IVIDDELYITGRIKEVMIVRGRNIYPQDIEASVQRAHDALKPAG"
     CDS_motif       complement(2774..2836)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg343_3_0003"
                     /evalue="6.00E-05"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg343_3"
                     /protein_end="473"
                     /protein_start="452"
                     /score="15.7"
                     /tool="antismash"
                     /translation="TGRIKEVMIVRGRNIYPQDIEA"
     CDS_motif       complement(2918..3001)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg343_3_0002"
                     /evalue="1.90E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg343_3"
                     /protein_end="425"
                     /protein_start="397"
                     /score="42.5"
                     /tool="antismash"
                     /translation="GVVGEIWVSGPCVAHGYWRRPDASAQTFG"
     CDS_motif       complement(3626..3682)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg343_3_0001"
                     /evalue="1.20E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg343_3"
                     /protein_end="189"
                     /protein_start="170"
                     /score="21.0"
                     /tool="antismash"
                     /translation="AFLQYTSGSTGVPKGNVVTF"
     CDS             complement(4313..5584)
                     /NRPS_PKS="Domain: PKS_ER (58-330). E-value: 6.5e-20.
                     Score: 63.2. Matches aSDomain:
                     nrpspksdomains_ctg343_4_PKS_ER.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 288.5; E-value: 1e-87)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg343_4"
                     /transl_table=11
                     /translation="VTIIDLDSRSKDITEGPAILFGLGQDIPLGVIPERMHAWTIRREG
                     HGDPSTAFQREVVDVPAVGPDEVLVLVMAAGVNYNGIWAALGHPVSPMDFHDHSFHIAG
                     SDASGIVWAVGSNVRNWRVGDEVVAHCCQVAGDDEECNGGDPMLSASQKIWGYETSYGA
                     FAQFTRVQAAQLMPRPRHLSWEASACYTLVLATAYRMLFGHAPHVIGPGKTVLIWGAAG
                     GLGSMAIQLAAIVGAKPIAVVSDEAKAAHARKLGAAATINRSQFDCWGPPPTIGSPDHA
                     AYLDKVKAFGRAVRQAAGPGGEVDIVFEHPGRDTFAVSSFLVKRGGMVVFCAATSGYDL
                     TFDARYVWMRQKRIQGSHFANLKQAAEANRLVMAGRIDPCLSELFAWDQLPAAHAKMLR
                     NQHLPGNMAVLIHAARPGEGARLE"
     aSDomain        complement(4595..5410)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg343_4_PKS_ER.1"
                     /evalue="6.50E-20"
                     /label="ctg343_4_PKS_ER.1"
                     /locus_tag="ctg343_4"
                     /protein_end="330"
                     /protein_start="58"
                     /score="63.2"
                     /tool="antismash"
                     /translation="DVPAVGPDEVLVLVMAAGVNYNGIWAALGHPVSPMDFHDHSFHIA
                     GSDASGIVWAVGSNVRNWRVGDEVVAHCCQVAGDDEECNGGDPMLSASQKIWGYETSYG
                     AFAQFTRVQAAQLMPRPRHLSWEASACYTLVLATAYRMLFGHAPHVIGPGKTVLIWGAA
                     GGLGSMAIQLAAIVGAKPIAVVSDEAKAAHARKLGAAATINRSQFDCWGPPPTIGSPDH
                     AAYLDKVKAFGRAVRQAAGPGGEVDIVFEHPGRDTFAVSSFLVKRGGMVVF"
     aSModule        4595..5410
                     /domains="nrpspksdomains_ctg343_4_PKS_ER.1"
                     /incomplete
                     /locus_tags="ctg343_4"
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       complement(4889..4951)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg343_4_0001"
                     /evalue="2.80E-06"
                     /label="PKSI-ER_m5"
                     /locus_tag="ctg343_4"
                     /protein_end="232"
                     /protein_start="211"
                     /score="19.9"
                     /tool="antismash"
                     /translation="GKTVLIWGAAGGLGSMAIQLAA"
     CDS             complement(5729..6949)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 303.3; E-value: 4.3e-92)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg343_5"
                     /sec_met_domain="p450 (E-value: 2.2e-24, bitscore: 75.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVDAFAHPDITSAGFFADRYPTYRVLRDNFPRFATEIDGEQCIML
                     TRYADVDEALRNPLITVQPEPGEFPPEERIGRGPASVYYREAFVNIDPPVHTRIRKIAT
                     PSMTPRAVGAMRGWVEEIVERNLAALEDESKVDFATAFASSVTAEVSCRLVHAPVADAQ
                     MLLSKAHELLAIVGVASMSSGALEIADAAGHFYYEYFEDLVNTLRRVDLPEDDIVRVLL
                     DAEGRENGVTHTELLTTLIGFLIAGYHTTQAAMTNGVLAFLRHPDQKDLLVANPDLARS
                     AWEEILRYDGSVHFRHRYVSRPVTIGGEPIEPGQRLLLGLQPANRDERQFPDPDRFIID
                     RPNNRHLALAAGPHFCIGVQLARLEGEVVFSRLFRRFPKMSISDVHLASHRDLSFPMIE
                     HLNLHLN"
     CDS             7658..8644
                     /locus_tag="ctg343_6"
                     /transl_table=11
                     /translation="MNLVDLYRLMRNAHIQAQSIVDTIPEPLLVLDDSLRVEAVSRSFY
                     DTFQVSEEETVGRPIYELGNGQWDIPDLRHLLEEVAARSTAVVDFEVDHDFPTIGRRTM
                     LISAHRLFQPDRSSRSMLVSIVDASKSRQREAESELLVGELRHRIKNLLAMIQALAQQT
                     MTEGRSAEQYRDDFLGRFRSLAAAQDLAFGGEGETGLRSLVEQTIQPFAGKGKVVVEPG
                     PAVELARTQIVPLSLILHELATNALKYGALSAPEGRVQIGWRMERDSAPRLRVHWQEHD
                     GPPVTPPATTGFGTRLIEFAVSRELGGRVELDYLPSGLTVEILLPIP"
     CDS             8662..9018
                     /locus_tag="ctg343_7"
                     /transl_table=11
                     /translation="VAKTILIVEDEFLIAMDLEMILRRHGWLILGPVATVVEALRLLQA
                     DQPSVAILDVTLKDGVVSPVAEALQDLDVPFIVSSAYRQPEAIGGEVLAGATNVGKPVD
                     EYRLLAALEDVARP"
     CDS             9165..9512
                     /locus_tag="ctg343_8"
                     /transl_table=11
                     /translation="MNKAQTDSSTQTAPTPEEERAADLCVLSELVEIHMSIARATQREA
                     LQAPQPGVDYGQRIATIARSVRLTLLLKAKLSRQAKEKRKAAAKREAAQEDWHALRVKL
                     AMTSAVYAVSKD"
ORIGIN
        1 cggccggcgc ggccggtggc cgcgcccggg gccagccggg cctcggtcct gtcggtcagc
       61 cggcgcatca gcttcgaccc tcccagatgg cgccgcccgg ccaccgccgc gaagcagtgg
      121 atcaggaccc agggcggcgt gtcccgggcc tgcatcccgg cgtcgccgag acgccggcgg
      181 gtgcagttcg ccgccgccct cgcatcgcgg cgcagccgtc cagcgaagcc ggtccggccc
      241 ggctcgctcc tcgtcacctt cttccgcatc ccggcctcgc aaaaataagc ccgccgcggc
      301 tgggccgggc gggcacaact gtctgactgt gcccgaatta tggtgcggga tgcggcatcg
      361 cgtcaagaac aaaaagagaa cataagatcg gagcggttgt ccgcgtgcgg gctctttgcg
      421 gacaacatcg gtatgaccct cggctccgct ccgtcctcca ttgccgacgt tcgcgagcct
      481 cctagaccct ttcgaaacgg acacgtccgg gtgttttccg ccggcaggtt gagccgacgc
      541 aggcccgcca tctgattgcc ggcgacttgc ggcagaacgg caacaccgat gccttgccta
      601 cacatgcgtc ccttcacgtt ccgattgctc aaactcagga tgagcctcac gttcgggaag
      661 cgctcctcga gccaagcgat accggagaac gtcggagacc tgcgttctat ttcaataatg
      721 tccgattttg ggattcaact gttcagagaa tgcagcagcc aattgccgcc ctgaaggcca
      781 aggtaatggt tctcgccccc ctgaatcagg cagacggtga tgtcgcgcag cagccgctcg
      841 acaacatggt cccgcgacag cccgttggcg ccgaagatct ggatcgcctc catcgccacc
      901 tcgaacgcgg tctgcgtcgt cgtggtcttc gcggtgatgg aggcgagaag atgcggccct
      961 tccggcgaga gattataggt gacaccccgg cggaccgagg cgcggcagag ctcgagtttc
     1021 cgccacattt cccatagccg ccatctgaca tgctgatgcg caaccagctt gaccccgccc
     1081 tgctcgcgcg actgggcata atgcagggcg cagtcgagtg cggccttcgc cacgccggtg
     1141 gcgatagcgg cgacgttcat ggccccggag gcatgtgtcc cggctatcga ggcgtaaaac
     1201 gcgtcctggc cccggatgat gtagcgggcc gggacacgga catcgctgaa ccggacattc
     1261 ccggtcggca gcgtgcgctg gccgatcttc tccaccggcc gtccacgctc gatgccaggc
     1321 aggtcgaacg ggaccagcag agcgatgccg gacaccccgc catccggccg ggcgatgccg
     1381 ccgccatagt ccgcagggca atggatcagg gcacattccg cgatcggagc acaggagatc
     1441 cagtcggaag acaccccgtt caggatcacc tcggagccgc gcatcatggc gcgcaggctg
     1501 ccttcccgct gccgggtgcc cttcgccagc tcgaaaccga catggtcgat ggcgtcggat
     1561 cctctatccg tcagggtcgc gatccagcaa ccgcgcagcg ggctgaaccg ctcgatcagc
     1621 tccgggtcgc cggtggctgc ggccaccccc ctggccatct tcgaggtgaa ggccgcgacg
     1681 gcgagaccgg cgtcgccata ggcgagctcc tcgaagacga gcggcagcat gcgcttgaga
     1741 cgctgggggc tgagcgttgc cagccaggtc gggttgatgc cgagttcgtc gaaccgcgac
     1801 agatactccc agagcggcga gccctcgccg atcacgtcca ccgctgccat cgggtccagc
     1861 ttggcggcgg tcgggcgcat cacgtcgagc gcaaagctct ggatcttccg ctggacgtcc
     1921 cgctcctcat ccgtcagctc ggcgtcgagt ccgccgaacc cgagccgggg gggcgcgaca
     1981 ttctggaagc tctgcattgg tccgttctcc atccactcac tccgccgcca ggggcatggg
     2041 ctgtgccatc tgctttgcgg tcgcccgagg aagccggcca tggcctcgac cgcgggcctg
     2101 cacctcggac cgactaccag ccggccgatt ccgcgatcgc ctgtgccggt gccgccacct
     2161 tggccccgcc cggggcgccg ggcgcctgca gcgcggccag atgacgcgac agggtctcga
     2221 ccgtggtgca ggtccacagc agtgtctggt cgagctcgag tcccagctcg gtctcaagga
     2281 aatgggtcag ctcgacggcg ctgatggaat cgaagccggc ctcggcgaag gtttggccgg
     2341 cttcgggggg ccggattcct cggccggccg cccagcgcgc gatcagcgcg ggaatggcgc
     2401 tcaccccgtc cgccggcacc gtggcgtcgg ccgccgtcac ggcgatcggc gcgatcctgg
     2461 tcgatcggcc ctggatcgcc tgctccagct tgccgcgccg atacaggtcg cggcacagca
     2521 cgcgctggat cttgccggcc gacgtcttcg gcacggtctc gggcttggtc agcacaacct
     2581 ccgccaccgt gagctcgtgc tcctggaaga cggcatcccg gatccgggcg atcagatcct
     2641 cgcgattcgc agtcgccaac caggaccgct cgatctcttg gaccacgacg atcgcctcgc
     2701 catcctcacg gtcgatcgag aacaccgccc cgcccgcggg cttgagggcg tcgtgcgcgc
     2761 gctgcacgct ggcctcgatg tcctgaggat agatgttccg gccgcggacg atcatgacct
     2821 ccttgatccg gccggtgatg tagagctcgt cgtcgatgac gatgccgaga tcccccgtcc
     2881 gcaggaacgg cccctggcca tccgccaagc gcgtgccgaa ggtctgggcg gacgcgtcgg
     2941 gacgtcgcca gtagccatgg gcgacgcagg ggcccgatac ccagatctcg ccgaccacgc
     3001 cttcctcgca gacttggcgg gacgcgggat cgacgatggt gacccgctgc ggccgtcgca
     3061 ccttgccgga gcctgcgatc cggcgagatc gcggaccgtc agccggcaca atccgccccg
     3121 tatcgagcgc ggccgcgtcg actgagaggg tcgccggcag ccgatcaaga tcggcgaccg
     3181 aaatcatcag cgttgcctct gccagcccgt atgccggctg gaaggcctcc tctcggaagc
     3241 cgcagtctcg gtacgcctct gcgaaggcac tcatcgtcgc cgcgcggatc ggctcggcgg
     3301 cattgagggc gcaccgccag ctcgacaggt cgagagcatt ctgcctgtcg gtcgggatgc
     3361 ggcggacgca gagatcgtag gcgaagttcg gcgccatgct gatcgtggcc cggtaccggc
     3421 tgatggtctc gagccaccgc cggggattct ggatcaccga caccggtggc aacaggacgc
     3481 agagcgcgcc gtcgagcagc gactggagga tgttcccgat cagcccgagg tcgtgatagg
     3541 gcggcagcca gcacacgatc gtcgcgtcga aatcgaagcc gcagcccacg ccgacgacgg
     3601 acgcattggc aatcaggttg ccaaaggtca cgacgttgcc cttggggacc ccggtcgatc
     3661 ccgaggtgta ttgcagaaaa gccggttcgt ctgctggcgg gcgttgccag tcgatatcgg
     3721 acgggtccgc atccagatcg ccaggagaca gcatcgggag caatgacagc tccgggctat
     3781 cgacgaacca gcccgtgagt ttcgggatcg acgcttcctc ggagagaatg gccacggcgc
     3841 cggcatcgcg cacgatcgcg accagccgat cccaggtgga ccggcccggc ttggccaagt
     3901 ggcaaggcac cgcggtgaca cccgcgcgca ggcaggccat aaacgccacg atgaagccgg
     3961 caccaggctc gaacagcatc agcgcccgct gcccggccaa gccgcgctca attagcccgg
     4021 cagcatatcg ctccacctgc gcgccgagct cgccataggt cagccggagc ttctcggcgc
     4081 cgtcggcgcc gacgacgacc agcgcgtcct tggccggatg ggcctcggct cttcgggcga
     4141 gaatatccga gaagcagcgg tcatcagcct tcgccagcgg gtccgttgcc atcgatgtct
     4201 ccttgcgccc ggaaacggcg cagcatcggg gtgatccgca cctgaaggag gcgcggggtt
     4261 cggtccagtc cgtcagtgtc ggtatcgtgc gtccctggcc ggtctcagcc ggtcattcca
     4321 gccgcgcacc ctcaccggga cgagcggcat ggatcaggac cgccatgttt ccgggaaggt
     4381 gttggttccg cagcatcttg gcatgggccg ccggcagctg gtcccaggcg aacagctcgg
     4441 acaggcacgg atcgatccgg cccgccatga ccaggcggtt ggcttcggcc gcctgcttca
     4501 gattggcgaa atggctgccc tggatccgct tctgccgcat ccacacgtag cgggcatcga
     4561 aggtcaggtc gtagccgctg gtcgccgcgc agaacaccac catgccgccg cgcttcacca
     4621 ggaagctcga gaccgcgaag gtgtcccggc ccggatgttc gaacacgatg tcgacctcgc
     4681 cgccgggacc ggccgcctgg cgcacggccc gcccgaacgc cttgaccttg tccagatagg
     4741 cggcgtggtc gggcgatccg atcgtcggcg gaggccccca gcagtcgaac tgggaccggt
     4801 tgatcgtcgc cgccgcgccg agcttgcggg catgggcggc cttcgcctcg tcggaaacca
     4861 ccgcgatcgg cttggccccg acgatggccg cgagctggat ggccatggag ccgagcccac
     4921 ccgcggctcc ccagatgagc accgtcttgc ccggcccgat gacatgcggc gcgtgcccga
     4981 acaacatccg gtacgcggtg gccagaacca gcgtgtagca ggcgctggct tcccagctca
     5041 gatgcctcgg tcgcggcatc agctgggcgg cctggacgcg ggtgaactgg gcgaaggcgc
     5101 cgtaggatgt ctcgtagccc cagatcttct ggctggccga cagcatcggg tcgccgccgt
     5161 tgcactcctc gtcgtcgccg gcgacctggc agcaatgggc cacgacctcg tcgccgacac
     5221 gccagttgcg gacattcgag ccgaccgccc agacgatccc ggacgcgtcc gagccggcga
     5281 tgtggaagga atgatcgtgg aagtccatgg gcgacacggg gtggccgagc gccgcccaga
     5341 tgccgttgta gttgacgcca gctgccatca ccaggacgag gacctcgtcc gggccgaccg
     5401 ccggaacatc gacgacctcc cgttgaaagg cggtcgaggg gtcgccgtga ccctctcgcc
     5461 ggatcgtcca ggcatgcatt cgctccggga tgacgccgag cggaatgtcc tggcccaacc
     5521 cgaatagaat cgcaggcccc tcggtgatat ccttggatct actgtccaga tcgatgatag
     5581 tcacggcatt ctcttctcat gagcccacgc ggcctccttc gcaggtatgg ttaccagcgc
     5641 gatgcactat cgatgtgggc cagggatacg ctaatgttgc taaggtgaga tatccgtgcg
     5701 cacgaaacgc actaacggct tccttgacct agtttaggtg gagattgagg tgctcgatca
     5761 tcgggaacga cagatcccga tgtgacgcca agtgcacgtc gctgatgctc atcttcggaa
     5821 atcggcggaa gaggcggctg aagacgactt cgccttccag ccgggccagc tggacgccga
     5881 tgcagaagtg aggtccggcg gccagggcga gatgccgatt gttgggccgg tcgatgatga
     5941 agcggtctgg gtccggaaac tgccgctcat cgcggttcgc gggctgcagg ccgagcaaca
     6001 gccgctggcc cggctcgatg ggttcgccgc cgatcgtgac cgggcggctg acatagcggt
     6061 gccggaaatg cacggacccg tcgtagcgca ggatttcttc ccaggcggac cgtgcgaggt
     6121 ccgggttggc gacgagcaag tccttctggt cgggatggcg aaggaacgcc aggaccccgt
     6181 tggtcatcgc tgcctgagtt gtgtgatagc ccgcgatcag gaacccgatc agcgtcgtga
     6241 gaagctcggt atgggtcacg ccgttctcgc ggccctccgc atcgagcaga actcggacaa
     6301 tatcgtcctc gggcaggtcc acgcgcctca gggtgttcac caggtcctcg aagtactcgt
     6361 agtagaagtg ccccgccgca tcggcgattt cgagcgcacc tgaagacatg ctggccacac
     6421 cgacgatcgc gagcagctca tgtgccttcg acagcagcat ctgcgcgtcg gcaaccggtg
     6481 catggacaag cctgcaggaa acttctgcgg tgaccgagga cgcgaaagcc gttgcgaaat
     6541 cgaccttgga ttcgtcctct agcgcggcca ggttccgctc gacaatctcc tcaacccacc
     6601 cccgcatcgc cccgaccgcc cgtggcgtca tcgacggggt cgcaatcttc cgtatacgcg
     6661 tgtgaacggg cggatcgatg ttgacgaagg cttcgcggta atagaccgac gccggtcccc
     6721 tgccaattcg ctcctctggc gggaattccc caggctcggg ttgcaccgtg atgagtggat
     6781 ttctcaacgc ctcatctaca tccgcgtagc gggtgagcat aatgcactgc tccccgtcga
     6841 tctcggtggc gaagcgagga aaattgtcgc gcagcacgcg ataggttgga tagcggtcgg
     6901 caaagaagcc ggccgacgtg atatcagggt gcgcgaaagc atccaccatt cgtctccatg
     6961 gctattgctt gcgatgatcc agcttgagcg ggtcagacca ggcagatgcg gcaccgacgt
     7021 tgcccctctc cttggtcagc ttccgactcc tgcggcggga tggccgtttc agtcccttgg
     7081 tcgacgctag gggatggtga gagcaggccc ctgatcatcg acacgagtgg aagtcagttc
     7141 ggtctggctc tcgatgcaca tctttgtttc tcacccgcct aatgttccta aggaaaggag
     7201 cggaattcat ctttcctcca ccgatcaatc cgaacatcga aacgatattc tgaatcatct
     7261 gagggtcaaa ctgaatcttc cgtggaatat tttattatat aaattgtata attaagaaaa
     7321 atgtcaggca agcggagccc ctattattaa tacaattctg cgtcttgttt gccatctgga
     7381 ttaattcgca ttccgttcta ctttggaata atatgctgcg ggcataatga tgcgctgctg
     7441 gccgcctgga cgaatcgcag acgggggtgc gtggtggatt tcggcgccgg cccgcccggc
     7501 tccctggaac cggacaattc cttatggcca tattgcctgg tggtggagcg ccatccatac
     7561 ttgaatgagg gccaactatt cgcgtcccgc tcgctgttcc gatgcggcgg cgcgatcgcg
     7621 gctctgaatt ggccggatgc gagagggacc ggcgcatatg aatctggtcg atctctaccg
     7681 tctgatgcgc aatgcgcata tccaggccca aagtattgtc gataccattc ctgagcccct
     7741 gctcgttctc gatgacagcc tgcgcgtcga ggccgtcagc cgaagcttct acgacacgtt
     7801 tcaggtcagc gaggaagaga ccgtcggccg gccgatctat gaattgggca atggccagtg
     7861 ggatattccc gatttgcgcc atctgctcga agaggtcgcg gccaggagca ctgcggtcgt
     7921 cgacttcgag gtcgatcacg acttcccgac catcggccgg cgaacgatgc tgatctcggc
     7981 gcaccggctg ttccagcccg accggtcgag ccggagcatg ctggtgtcga tcgtcgatgc
     8041 gtcgaagagc cggcagcgcg aagcggaatc ggagctgctc gtcggcgagc tgagacatcg
     8101 gatcaagaat ctgctggcga tgatccaggc gctggcgcag cagaccatga ccgaaggccg
     8161 ttccgcagag cagtaccgtg acgatttcct cggcaggttc agatccctgg cggcggcgca
     8221 agacctggcg ttcggaggcg agggggagac cgggctgcgc agcctggtcg agcagacgat
     8281 ccaacccttt gccggcaagg ggaaggtggt ggtcgaaccc ggaccggcgg tggagctcgc
     8341 gcgcacgcag atcgttcccc tcagcctcat cctgcatgag ctcgcaacca acgccctgaa
     8401 atatggcgcg ctgtcggcgc ctgaaggccg cgtgcagatc ggctggcgca tggaacggga
     8461 cagcgcgccg cgcctccgcg ttcattggca ggagcatgac ggtcctccgg tgacgccgcc
     8521 cgccacgacc ggtttcggca cgcgtctcat cgagttcgcc gtatcgcgcg aacttggcgg
     8581 gcgagtggaa ctcgattacc tgccgtccgg tttgacagtg gagatcctgc tcccgatacc
     8641 ttgatctcct ggaccgttcc ggtggcgaaa acgatactca ttgtcgagga cgagttcctc
     8701 atcgccatgg acctcgaaat gatcctccgc cggcatggct ggctcattct cggacccgtg
     8761 gccaccgtcg tggaggcatt gcggctgctg caggcggacc agccgtccgt ggccatcctc
     8821 gacgtcacgc tgaaagacgg ggtggtgtcg cccgtcgccg aagccctcca ggacctcgac
     8881 gtgcccttca tcgtgtcgag cgcctatcgg cagcccgaag ccatcggcgg agaggtcctg
     8941 gccggagcga ccaacgtcgg caagccggtc gacgaatatc ggctcctggc ggccctcgag
     9001 gacgttgcgc gaccttgatc gggccgaggc accgatccgc aatcgaactg gagcagagcc
     9061 cgacccggtg catggcgagg tcggtgtcgg aagcctgcca tgatcgctgc agtaaacaca
     9121 ttgtgcagtt gtattatccg gcgtcttcgt tcatgttatg ttccatgaac aaggcgcaga
     9181 ccgattcgag cacgcagacc gcgcccactc ccgaggagga gcgggcggcg gatctgtgcg
     9241 tgctgtcgga gctggtcgag atccatatgt cgatcgcccg ggcgacgcag cgggaggcgc
     9301 tgcaggcgcc gcagcccggc gtcgactatg gccagcggat cgccaccatc gcgcgctccg
     9361 tgcggctgac cctgctgctc aaggccaagc tgtcccggca ggccaaggag aagcgcaagg
     9421 ccgcggcgaa gcgcgaggcg gcgcaggagg actggcacgc gctgcgggtg aagctggcga
     9481 tgacgtcggc ggtctatgcg gtgtccaagg ac
//
