LOCUS       c00015_3300025..       14891 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300025298.a:Ga0209050_1000009.
ACCESSION   c00015_3300025..
VERSION     c00015_3300025..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 09:55:52
            Original ID  :: 3300025298.a:Ga0209050_1000009
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 300349
            Orig. end    :: 315240
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14891
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[305349:310240]"
                     /cutoff="10000"
                     /detection_rule="((TIGR03104 or cds(GATase_7 and
                     Asn_synthase)) and TIGR03103 and (TIGR03106 or
                     Peptidase_M42))"
                     /neighbourhood="5000"
                     /product="NAGGN"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..9891
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((TIGR03104 or cds(GATase_7 and
                     Asn_synthase)) and TIGR03103 and (TIGR03106 or
                     Peptidase_M42))"
                     /neighbourhood="5000"
                     /product="NAGGN"
                     /protocluster_number="1"
     cand_cluster    1..14891
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((TIGR03104 or cds(GATase_7 and
                     Asn_synthase)) and TIGR03103 and (TIGR03106 or
                     Peptidase_M42))"
                     /kind="single"
                     /product="NAGGN"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14891
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NAGGN"
                     /region_number="1"
                     /rules="((TIGR03104 or cds(GATase_7 and Asn_synthase)) and
                     TIGR03103 and (TIGR03106 or Peptidase_M42))"
                     /tool="antismash"
     CDS             423..2516
                     /locus_tag="ctg15_261"
                     /transl_table=11
                     /translation="MAIPDALSQQRNTHRLLQPTVKSHLAYTLLCALVMMVMFSLLRVA
                     LLVYNREMILDTPASTFVEAFVNGLRFDLRLVVYLCIPLLLALFSARAMAARGFFRFWL
                     TVTSSIALFLGLMEMDFYREFHQRLNGLVFQYVKEDPKTVMSMLWYGFPVVRYLLAWVG
                     GTLILSLAFKGADRATRPRGPFSGGTIGTRQIAPWYGRVAVFMVCLLVAVAAARGTLRQ
                     GPPLRWGDVYTTDSNFANQLGLNGTLSLVAAAKSRMSEDRDNIWKATLEQPLAQQTVRD
                     MLVMPDDKLVDTETAAVRRDYTPPADKTLPIKNVVVILMESMAGHSVGALGAPGNITPY
                     LDKLSKEGLLFDRFFSNGTHTHQGMFATMACFPNLPGFEYLMQTPEGSHKLSGLPQLLS
                     ARDYDDVYVYNGDFAWDNQSGFFSSQGMTNFIGRNDFVNPVFSDPTWGVSDQDMFDRGL
                     IELKARENGKPFYALLQTLSNHTPYALPTPLPVERVTDRGSLNEHLTAMRYADWALGQF
                     FEKARKEPYFKETLFVVVGDHGFGNERQITEMDLGRFNVPMLLIGPGIQEKFGQRNHTV
                     GTQVDIVPTIMGRIGGQVRNQCWGRDLLNLPQGDPGFGVIKPSGSEQTTAIIRDDQILV
                     LPKEKEMAPKMYRYELGANPHAEIIPDAADTAQMKLKLESFLQTATKSLLDNTAGVVDG
                     KPD"
     CDS             complement(2580..2732)
                     /locus_tag="ctg15_262"
                     /transl_table=11
                     /translation="MGTILIIILILLLIGGLPVFPHSRSWGYGPSGIIGVVLVVLLVLL
                     LLGKI"
     CDS             3022..3837
                     /NRPS_PKS="Domain: PKS_KR (4-163). E-value: 1.3e-10. Score:
                     33.2. Matches aSDomain: nrpspksdomains_ctg15_263_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     194.4; E-value: 3.7e-59)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg15_263"
                     /sec_met_domain="adh_short (E-value: 5e-34, bitscore:
                     113.7, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQNRMMITGAGSGLGREIALRWAREGWRLALSDVSEPGLVETLKL
                     VRAAGGDGFTQRCDVRDYSQLTAFAQACEEKLGGIDIIVNNAGVASGGFFSELSLEDWD
                     WQIAINLMGVVKGCKAFLPLLEKSRGKIINIASMAALMQGPAMSNYNVAKAGVVALSES
                     LLVELAQQEIGVHVVCPSFFQTNLLDSFRGPTPAMKAQVGKLLESSPISAADIADYIYQ
                     QVAQGQFMILPHEQGRMAWALKQKNPQLLYDEMTVMADKMRAKARQNLN"
     aSDomain        3034..3510
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg15_263_PKS_KR.1"
                     /evalue="1.30E-10"
                     /label="ctg15_263_PKS_KR.1"
                     /locus_tag="ctg15_263"
                     /protein_end="163"
                     /protein_start="4"
                     /score="33.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="MMITGAGSGLGREIALRWAREGWRLALSDVSEPGLVETLKLVRAA
                     GGDGFTQRCDVRDYSQLTAFAQACEEKLGGIDIIVNNAGVASGGFFSELSLEDWDWQIA
                     INLMGVVKGCKAFLPLLEKSRGKIINIASMAALMQGPAMSNYNVAKAGVVALSESL"
     aSModule        3034..3510
                     /domains="nrpspksdomains_ctg15_263_PKS_KR.1"
                     /incomplete
                     /locus_tags="ctg15_263"
                     /tool="antismash"
                     /type="unknown"
     CDS             3895..4227
                     /locus_tag="ctg15_264"
                     /transl_table=11
                     /translation="MLNYLWFFLAALFEIAGCYAFWLWLRQGKSAWWIVPALLSLTLFA
                     LLLTRIEATYAGRAYAAYGGIYIIASIGWLAMVERVRPLGSDWIGVALCVLGASVILFG
                     PRLSAP"
     CDS             4379..4579
                     /locus_tag="ctg15_265"
                     /transl_table=11
                     /translation="MLVLSRAVGELISIGDDISVRVLSVSGGTVRFGVEAPRHVDVHRS
                     EIYDKIQKRKAQATRKACSVE"
     CDS             complement(4568..4795)
                     /locus_tag="ctg15_266"
                     /transl_table=11
                     /translation="MLIPHDQLEVDTLTRLIEDFVTRDGTDNGDDTPLETRVLRVRQAL
                     TKGQALIVFDPESEQCQLMLKHDVPKHLFD"
     CDS             complement(5001..6191)
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     Peptidase_M42"
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     TIGR03106"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_267"
                     /sec_met_domain="TIGR03106 (E-value: 5e-177, bitscore:
                     583.6, seeds: 7, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_M42 (E-value: 2.5e-74, bitscore:
                     245.7, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISKIPEPDLEYLQKVLLEMLAIPSPTGFTDTIVRYVAERLEELG
                     IAFEMTRRGTIRATLKGRKSSPDRAVSAHLDTIGAAVRAIKDNGRLTLAPVGCWSSRFA
                     EGSRVSLFTDTGVIRGSVLPLMASGHAFNTAVDEMPISWDHIELRLDAYCATRADCESL
                     GVGIGDYVAFDPLPEFTESGHISARHLDDKAGVAALLAALKAIVDSGEELLIDCHPLFT
                     ITEETGSGAAAALPWDVSEFVGIDIAPVAPGQHSSEHAVSVAMQDSGGPYDYHLSRHLL
                     KLAKENEVPARRDLFRYYFSDAHSAITAGHDIRTALLAFGCDATHGYERTHIDSLAALS
                     RLLGAYILSPPVFASDAQPAQGSLDRFSHQIEHDAQMESDTRVPSVDSLVGQRSDS"
     CDS             complement(6370..8115)
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     TIGR03103"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_268"
                     /sec_met_domain="RimK (E-value: 2.9e-10, bitscore: 35.9,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03103 (E-value: 1.1e-269, bitscore:
                     891.3, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPYATVHNQRLLRGQAPSYERLQARLAEDGSELGADPIAVHCGW
                     GRLLIGHTFPDPASLARELLNEQPGERDIALYVAAPQQVLGLEPAQLFLDPSDTLRLWF
                     SDYRQATRVFRGFRIRRAQGETDWQAINQLYQARGMLPIDPQRLTPRHEGGPVYWLAED
                     DDTGAVIGSVMGLNHQKAFNDPENGSSLWCLAVDPQCQRPGVGEVLVRHLVEHFMSRGL
                     SYLDLSVLHDNRQAKNLYAKLGFRNLSTFAIKRKNGINQPLFLGPGPEAQFNPYARIIV
                     EEAHRRGIEVQVDDAEAGLFTLVHGSRRVRCRESLSDLTSAISMTLCQNKSLTHKVLKN
                     AGLNLPAQQLAGNADDNLAFLDEHERVVVKPLDGEQGQGVAVDLRTIEEVQSAIEAARR
                     FDSRVLLESFHEGLDLRILVIGFEVVAAAIRRPAEVIGDGRHTIGALIEAQSRRRQAAT
                     GGESKIPMDAETLRTLSTAGFDYDSVLPAGEHLFVRRTANLHTGGVLEDVTSILHPTLV
                     DAAVRAARALDIPMVGLDLLVPAADQPEYVFIEANERAGLANHEPQPTAERFVDLLFPH
                     SQAVA"
     CDS             complement(8119..9891)
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     TIGR03104"
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     Asn_synthase"
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 596.5; E-value: 9.4e-181)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_269"
                     /sec_met_domain="Asn_synthase (E-value: 1.1e-83, bitscore:
                     277.7, seeds: 78, tool: rule-based-clusters)"
                     /sec_met_domain="GATase_7 (E-value: 3.5e-43, bitscore:
                     142.3, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03104 (E-value: 1.8e-296, bitscore:
                     979.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGLAGELRFDQQPADLAAVERITHHLAPRGPDAWGFHSQGPIAL
                     GHRRLKIMDLSDGSAQPMIDNQLGLSLAFNGAIYNYPELRTELEGLGYTFYSGGDTEVL
                     LKGYHAWGEALLPKLNGMFAFAIWERDAKRLFIARDRLGVKPLYLSRTGQRLRFASALP
                     ALLKGGDINPVLDPVALNHYLNFHAVVPAPRTLLAGIEKMPPATWMRIEADGSTEQKTW
                     WTLPYGPRADEQHLNLEDWIDRVLDSTREAVAIRQRAAVDVGVLLSGGVDSSMLVGLLR
                     EVGVEDLSTFSIGFQDAGGERGDEFQYSDLIAKHYGTRHHQLRIDEKEIIEQLPAAFRA
                     MSEPMVSHDCIAFYLLSREVAKHCKVVQSGQGADELFAGYHWYPQVDGASDPYAAYRAA
                     FFDRSYEEYAATVQPKWLTANDAAGDFVKEHFAQPGANAAVDKALRLDSTVMLVDDPVK
                     RVDNMTMAWGLEARTPFLDYRLVELSARVPAKFKLPDGGKQVLKEAARRVIPSEVIDRK
                     KGYFPVPGLKHLEGNTLAWVRELLLDPSQDRGLFNPAMLDRLLTDPNGQLTPLRGSRLW
                     QLAALNLWLSEQGI"
     CDS             complement(10168..12150)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103:FAD dependent oxidoreductase (Score: 114.4;
                     E-value: 1.2e-34)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg15_270"
                     /transl_table=11
                     /translation="MTPIQQHAQLDWDDQGRPRSRVFDDVYFSDQSGLDETRYVFLEQN
                     NLAERFAALADDERLVIGETGFGTGLNFLCAWQLFEQCAPTGARLHFVSVEKYPLSPRD
                     LRRALELWPQLKHQAEQLLEQYVAVHQGFQRLTLAGGRVTLTLLIGDALEQLPQLDGQI
                     DAWFLDGFAPAKNPEMWTAELFAELARLAAPDATLSTFTSTGWVRRSLNAAGFKMKRTP
                     GIGHKWEILRGVFLGWPEQTPAPAPAKPWYARPTTLIGERRALVIGGGLAGCASAASLA
                     ARGWQVTLLERHAGLAEEASGNPQGVLYLKLSAHGTALSQMILSGFGYTRRVLEQLQRG
                     VDWDACGVLQLAFNGKEAERQAQLAEAFPRDLLHTLDQSEAQVRSGIDLACGGLFYPEG
                     GWVHPPALCRWQASQPGIDVQPHHEVLQLRRIDGQWQAWDGERCLASAPVAILASAAEI
                     KRFEPAAELPLKRIRGQITRLPQTTRSQSLATVVCAEGYVAPPRLGEHTLGASFDFNSD
                     DLTPTAAEHAGNLRMLEEISQDLVERLNAATLDPQHLEGRAAFRCTSPDYLPIVGPLAD
                     RQAFTEAYAALGKDARQVPDTPCPWLDGLYINSGHGSRGLITAPLSGELIAAWLDNEPL
                     PLPRSVAEACHPNRFALRALIRGKA"
     CDS             12301..13815
                     /locus_tag="ctg15_271"
                     /transl_table=11
                     /translation="MFESAEIGHAIDKDTFEAEVPALREALLEAQFELQQQGRFPVIVL
                     INGIEGAGKGETVKLLNEWMDPRLIEVRTFDQQTDEELARPPAWRYWRMLPAKGRMGIF
                     FGNWYSQMLQGRVHGEFKDPRLDQAIAGAERLEKMLCDEGALIFKFWFHLSKKQMKARL
                     KGLKDDPLHSWRISPLDWQQSQTYDKFVKYGERVLRRTSRDYAPWHVIEGMDSCYRSLT
                     VGRILLDGLRQALDRSKVKPQKVSVAPLPELDGQITLLDSLDMTRRLDKADYEEQLITE
                     QARFAGLLRDKRMRQHALVAVFEGNDAAGKGGAIRRVTAALDPRQYSIVPIAAPTEEER
                     AHPYMWRFWRHIPARGKFTMFDRSWYGRVLVERVEGFCSQADWLRAYGEINDFEEQLAD
                     AGVVVVKFWLAIDKETQLERFQEREDIPFKRFKITEDDWRNRDKWDAYRAAVCDMVDRT
                     STEISPWTLVEANDKRWARVKVLRTLNQALEAAFERSARQARKKKR"
ORIGIN
        1 tggaacaacg gttggagccg ttcagtcagc cccaatggcc catgggaaga caccaccatc
       61 gaaggtgtgc cggcgggctt ggggcggcaa ttccactaag cacgggcccc tggagccaga
      121 gggcatctgt gggagcaagc tttgctccca cagataaatc cttttgccac aatagcgttc
      181 ggctcaactt catcaatcgg ccgggctttt ttgtgtttcc ggatattctt tgaacgaaat
      241 tttcacaaaa tcttgcggac aatcccccgc gcttatatcg ccgccggtta tttaatggca
      301 atgccatagc cgttcgtgca acatttgcgc tctcgcgcaa gccccgaggc caggctttgg
      361 tcaacagagg gcgcgccgtt gtttcttttg tcactccaac tccaataggg tccttaaacg
      421 acatggcaat cccggacgcc ctgagtcagc agcgcaatac gcatcgcctg ctgcaaccga
      481 ccgtcaaatc gcacctggcc tatacgttgc tttgcgccct ggtgatgatg gtcatgttca
      541 gcctgctgcg cgtggcgctg ctggtctata accgcgagat gatcctcgac accccggcct
      601 cgaccttcgt tgaagcgttc gtcaacggcc tgcgtttcga cctgcgcctg gtggtctacc
      661 tctgcatccc gttgctgctg gcattgttca gcgccagggc catggcggcc cgtgggttct
      721 ttcgtttctg gctgaccgtc acctccagca tcgcgctgtt cctgggcttg atggagatgg
      781 atttctaccg tgaattccac cagcgcctca acggcctggt cttccagtat gtaaaggaag
      841 acccgaaaac cgtgatgagc atgctctggt acggtttccc ggtggtgcgc tacctgctgg
      901 cctgggtcgg cggcaccctc atcctgagcc ttgctttcaa gggcgctgac cgcgccactc
      961 ggccccgtgg gccgttcagt ggcggcacca tcggtacccg gcagatcgct ccgtggtatg
     1021 ggcgtgtcgc ggtgttcatg gtttgcctgc tggtggccgt ggccgctgca cgcggcaccc
     1081 tgcgccaagg cccgccgctg cgttggggtg acgtctacac caccgattcg aacttcgcca
     1141 accagttggg cctcaacggt acgttgtcgc tggtggcggc ggccaagagc cggatgtccg
     1201 aagaccgcga caacatctgg aaagccaccc ttgaacaacc gctggcacag cagaccgtgc
     1261 gggacatgct ggtgatgcct gacgataaac tcgtggacac cgagaccgcc gccgtgcgcc
     1321 gcgactacac gccgccagcg gacaagaccc tgccgatcaa gaacgtggtc gtgatcctca
     1381 tggaaagcat ggccggtcac tcggtgggcg ccctgggcgc accgggcaac atcacgccat
     1441 acctggacaa gctgtccaag gaaggcctgt tgttcgaccg tttcttctcc aacggcaccc
     1501 acacccacca aggcatgttc gccaccatgg cgtgcttccc gaacctgccg ggtttcgaat
     1561 acctgatgca gacgccggag ggcagccaca agctgtcggg cctgccgcaa ctgctcagcg
     1621 cccgtgacta cgacgacgtg tatgtctaca acggcgattt cgcctgggac aaccagtcgg
     1681 ggttcttcag cagccagggc atgaccaact tcatcgggcg taacgacttc gtgaacccgg
     1741 tgttctccga tccgacctgg ggcgtgtccg accaggacat gttcgatcgt ggcctgatcg
     1801 agctcaaggc gcgggaaaac ggcaagccgt tctatgcctt gctgcaaacc ctgtccaacc
     1861 acacgccgta tgctctgccg acaccgttgc ccgtggagcg ggtcaccgac cgcggcagcc
     1921 tgaacgaaca cctgaccgcc atgcgctacg ccgactgggc actgggccag ttcttcgaga
     1981 aggcccgcaa ggagccgtac ttcaaggaaa ccctgttcgt ggtggtcggc gatcatggtt
     2041 ttggcaacga acgccagatc accgaaatgg acctgggccg tttcaacgtg ccgatgctgc
     2101 tgatcggccc gggcatccag gaaaaattcg gccagcgtaa ccataccgtg ggcactcaag
     2161 tcgacatcgt gccgaccatc atgggccgca tcggcgggca agtgcgcaac cagtgctggg
     2221 gccgcgacct gctgaacctg ccgcaaggcg accctggttt tggtgtgatc aagccgtcgg
     2281 gcagcgaaca gaccacggcg atcatccgcg atgaccagat cctggtactg ccgaaggaga
     2341 aggaaatggc gccgaagatg tatcgctatg agctgggcgc caacccgcat gcggaaatca
     2401 tcccggatgc agcggatacc gcgcagatga aactcaagct cgaatcgttc ctgcaaacgg
     2461 cgaccaagag cctgttggat aacaccgctg gcgtcgttga cggcaagccg gattgataaa
     2521 acggcgagca taaaaaagag gcctctagag gcctcttttt tttgcactta cttggtggtt
     2581 tatatcttgc ccagtaatag caggaccaac agcaccacca acactacacc aatgataccg
     2641 gacggaccgt aaccccaact tctggagtgc gggaagaccg gaagaccacc gatcagcagg
     2701 aggatcagga taatgataag aattgtgccc attgtagatt tccttattgg tcagttctgg
     2761 ggtgatacaa ctttcaactg ccagcgcgca tgcgttaaat ccgggcggct taataagtcc
     2821 gaccgtaacg tcctgtaaaa aattcaaagt tttttgtggt cgtatgaaag tgcaattgtg
     2881 cagcccaata cccacaaagg gcgctcctcg atcaaaaccc attacggttt gccctcgcca
     2941 ttcagcaatc tgatggagcg tgggtccgca gaactccttc gttacactcg gcctatctct
     3001 cccggaacaa ggctgtttgc tatgcaaaat cgcatgatga tcactggtgc cggctccggc
     3061 ctgggtcgcg aaatcgcgct gcgctgggcc cgcgaaggct ggcgtctggc cttgtcggat
     3121 gtcagcgagc caggccttgt ggaaaccctc aagctggtgc gcgccgccgg tggcgacggc
     3181 ttcacccagc gttgcgatgt gcgcgactac agccaattga ctgcgttcgc ccaggcttgc
     3241 gaagagaagc tcggtggcat cgatatcatc gtcaacaatg ccggcgttgc ctcgggcggg
     3301 ttcttcagtg agctttccct ggaggattgg gactggcaga tcgcaatcaa cctgatgggc
     3361 gtggtcaagg gctgcaaggc gttcttgccg ctgctggaga aaagccgcgg caagatcatc
     3421 aacatcgcct ccatggcggc cctgatgcag gggcctgcca tgagcaacta caacgtggcc
     3481 aaggctggag tagtggcatt gtcggaaagc ctgttggtgg aactggcgca gcaggaaatt
     3541 ggcgtacacg tggtgtgccc gtcgttcttc cagaccaatc tgctggactc cttccgcggc
     3601 ccgaccccgg ccatgaaggc ccaggttggc aagttgctgg aaagctcacc gatcagcgcc
     3661 gcggatattg ccgactacat ctaccagcaa gtcgcccagg gccagttcat gatcctgcct
     3721 catgaacagg ggcgcatggc gtgggccctc aagcagaaga acccacaatt gctgtacgac
     3781 gaaatgaccg tcatggccga caagatgcgc gccaaggccc ggcaaaacct gaattgacct
     3841 ggctgcccga tgtcctcagg atggcgccat tcggccttcc tgatggacat ctgcatgctc
     3901 aattacctgt ggttttttct cgccgcgctg tttgagatcg cgggctgcta cgccttctgg
     3961 ttgtggctgc gccagggcaa gagcgcctgg tggatcgtcc cggcattgct cagcctcacg
     4021 ttgttcgccc tgttactgac ccgcatcgaa gcgacgtacg ccgggcgcgc ctacgccgcc
     4081 tatggcggta tctatatcat tgcctcgatc ggctggctgg ccatggtgga gcgggtgcgg
     4141 ccattgggtt ccgactggat tggcgtggcg ctctgcgtgt tgggggcgag tgtgattcta
     4201 ttcggcccac gactctcggc gccctgaaac cacctgcgat ccgacagggt tttgcaggaa
     4261 gtttccgtca gtcacaggag ctttgcttgt agggccttac tgaattctcg cgggtgtctt
     4321 gagaacagga aacaggccgg gcatggtcag ggtccagaca ttcttaagga caagaaccat
     4381 gcttgtacta agccgcgctg taggtgagtt gatttccatc ggtgacgata tttccgtccg
     4441 tgtgctgtcg gtcagcggtg gcaccgtgcg ttttggcgtg gaagcgccac ggcacgtcga
     4501 tgtccatcgc tccgaaatct acgacaagat ccagaagaga aaggcccaag ccactcgcaa
     4561 ggcctgttca gtcgaatagg tgcttgggca cgtcgtgctt gagcatcagt tggcactgtt
     4621 cactttcggg gtcgaagacg atcaacgcct ggcctttggt cagggcttgt ctgactcgta
     4681 gaacccgtgt ttccaggggc gtgtcgtcac cattgtcggt gccgtcgcgg gtcacgaaat
     4741 cttcgatcag gcgagtgagc gtgtcgactt cgagttggtc gtgggggatg agcatggggt
     4801 acctcggcta gacaatgagg cgatgctacg gccaatgggc ttttgcggct agcctgggtt
     4861 ttacggttgt ttgttccggc ctcatcgtcg gaacgccgcc cggagcaagc tccccccagg
     4921 gtttttgagt cgcactgaaa actcaatgtg ggagcgagcc tgctcgcgat ggcgatattc
     4981 caggctgtga aaatgctgga tcagctatcg gaacgctgcc ccacaaggct atccaccgac
     5041 ggtacccggg tatcgctttc catctgtgca tcgtgctcga tctggtggct gaagcggtcc
     5101 agcgagccct gggccggttg tgcgtcgctg gcgaataccg gcgggctgag gatgtaggcg
     5161 ccgagcaggc ggctgagggc ggccaggctg tcgatgtggg tacgttcgta gccatgggtg
     5221 gcgtcgcagc cgaaggcgag cagggcggtg cggatgtcat ggccggcggt gatggccgaa
     5281 tgggcgtcgc tgaagtagta gcggaacagg tcgcggcgtg cgggtacctc gttttccttg
     5341 gccagtttca acaagtgtcg cgacaggtga tagtcgtaag ggcctccgga gtcttgcatc
     5401 gccacgctga ccgcatgttc gctcgaatgc tggccaggtg cgacgggcgc gatgtcgatg
     5461 ccgacgaatt cgctcacatc ccagggcagt gcagccgccg caccgctgcc ggtttcctcg
     5521 gtgatggtga acagggggtg acaatcgatc agcagttctt cgccgctgtc gacaatcgcc
     5581 ttgagcgccg ccagcagcgc cgcgaccccg gccttgtcat ccagatgccg ggcgctgata
     5641 tgaccgcttt cggtgaattc cggcaaggga tcgaaggcca cgtaatcgcc gatgcccacc
     5701 cccaggcttt cgcaatcggc gcgggtggcg caataggcgt ccaggcgcag ctcgatgtgg
     5761 tcccaactga tgggcatttc atccacggcg gtgttgaatg cgtgcccgga ggccatcaac
     5821 ggcaacacgc tgccccgaat cacgccggtg tcggtaaaca ggctgacccg gctgccttcg
     5881 gcaaaccgac tggaccagca acccaccggg gccagggtca ggcggccgtt gtccttgatg
     5941 gcccgcacgg cagcgccgat ggtgtccaag tgggccgata ctgctcggtc ggggctgctc
     6001 ttgcggccct tgagcgtggc gcggatcgtg ccgcggcggg tcatttcaaa agcgataccc
     6061 agctcttcga gtcgttcggc gacatagcgc acgatggtgt cggtgaatcc ggtggggctg
     6121 ggaatggcga gcatctccag caggaccttt tgcaggtatt cgagatccgg ttcgggaatt
     6181 ttgctgatca tggaaactcc tcacggaaca ttaaattgaa gtagggaacc tgtggcgagg
     6241 gagcttgctc ccgctggacc gcgcagcggt cccttttgag ctccaggtcg atgcaaaaac
     6301 ccggagggcc gcggagaagg gccgcttcgc agcccagcgg gagcaagctc cctcgccacg
     6361 gaagaagggc taggccaccg cctggctatg gggaaacaac aaatccacaa aacgctcggc
     6421 ggtgggttgt ggttcgtggt tggccaggcc tgcgcgttcg ttggcttcga tgaatacgta
     6481 ctcgggttga tcggccgccg gcaccagcag gtcgaggccg accatgggga tgtccagcgc
     6541 ccgcgcggcg cgcaccgccg catcgacaag ggtcggatgc aggatgctgg tgacatcctc
     6601 cagcacgcct ccggtatgaa ggttcgccgt gcgtcgtacg aacagatgct ccccggcggg
     6661 caacacgctg tcatagtcga accccgccgt gctgagcgtg cgcaaggttt cggcatccat
     6721 cgggattttg ctttcgccgc ccgtggccgc ttgccgtcgg cgactctggg cttcgatcaa
     6781 cgcgccgatg gtgtgccggc catcgccgat cacctccgcc gggcgccgga tcgctgccgc
     6841 caccacttca aaaccgatta ccaggatccg caggtccaat ccttcgtgga agctttccag
     6901 cagcacccgg ctgtcaaacc gccgagccgc ttcgatggcg ctttgcacct cctcgatggt
     6961 gcgcaggtcc actgccacgc cttggccttg ttcaccgtcc agcggcttga ccaccacccg
     7021 ttcgtgctcg tcgagaaacg ccaggttgtc atcggcattg cccgccaact gctgggccgg
     7081 caggttcagg ccggcattct tcagtacctt gtgggtcagg cttttgttct ggcaaagagt
     7141 catgctgatg gcgctggtca ggtcgctcag ggactcgcgg cagcgcaccc gacggctgcc
     7201 gtgaaccagg gtgaacaagc cggcctcggc atcgtctacc tgcacttcga tgccacgccg
     7261 gtgagcttct tcgacaatga ttcgcgcata aggattgaac tgcgcttcgg gacctggccc
     7321 gaggaacaac ggctggttga taccgttctt gcgtttgatg gcgaaggtcg agaggttgcg
     7381 aaagccgagt ttggcgtaga ggtttttcgc ctggcgattg tcatgcaaca ccgacaggtc
     7441 gaggtaactc aagccacggc tcatgaaatg ctcgacgagg tggcgcacca gcacttcgcc
     7501 aacaccgggc cgctgacatt gcggatcgac ggccaggcac cagaggctgc tgccgttttc
     7561 cgggtcgttg aaggccttct gatgattcag gcccatgacg ctgccgatca ccgcaccggt
     7621 gtcatcgtct tcggccaacc aatagaccgg gccgccttca tgacgtgggg tcagtcgctg
     7681 cgggtcgatg ggcagcatgc cccgggcctg gtagagctgg ttgatggcct gccaatcggt
     7741 ctcgccctgg gcccgacgga tgcggaaccc gcgaaacacc cgcgtggcct ggcgatagtc
     7801 gctaaaccac aggcgcaaag tgtcggatgg gtcgaggaac agttgcgccg gttccagccc
     7861 cagcacctgc tggggcgcgg cgacgtacaa ggcaatgtcg cgttcgccgg gttgttcgtt
     7921 gagcagttcc cgggccaggc tcgccgggtc cgggaaggtg tggccgatca gcagtcggcc
     7981 ccagccgcaa tgcaccgcga tcgggtcggc gcccaattcg ctgccgtctt cggccaggcg
     8041 cgcctgcagg cgttcgtagg acggtgcctg gccacgcaag aggcgttggt tgtgaacggt
     8101 tgcgtaaggt ttcatcgatc agattccttg ctcgctgagc cacaggttca gcgccgccaa
     8161 ctgccacagc cgcgacccgc gcaacggcgt gagctggccg ttggggtcgg tcagcaggcg
     8221 gtcgagcatg gctgggttga acaggccgcg atcctggctc ggatcgagca gcagttcgcg
     8281 gacccaggcc agcgtgttgc cttccaggtg cttgaggcca ggcaccggga aataaccctt
     8341 cttgcggtcg atcacctcgc tagggatcac ccgcctggcg gcttccttga gcacctgctt
     8401 gccgccatcg ggcagcttga atttcgccgg gacccgggcc gagagttcta ccaagcggta
     8461 atccaggaag ggcgtgcgcg cttccaggcc ccaggccatg gtcatgttgt cgacgcgttt
     8521 gaccgggtcg tccaccagca tcaccgtgct gtccaggcgc agggccttgt ccaccgccgc
     8581 attggcgccc ggctgggcga aatgctcctt gacgaaatca ccggcggcat cgttggccgt
     8641 cagccatttg ggttgcaccg tggcggcata ttcttcgtag ctgcgatcga agaaggcggc
     8701 gcgataggcc gcgtacggat cgctggcgcc atcgacctgc gggtaccagt ggtaaccggc
     8761 gaacagctcg tcggcgccct ggccgctttg caccactttg caatgcttgg ccacttcccg
     8821 tgacagcagg tagaaggcga tgcagtcgtg gctgaccatc ggctcgctca tggcacggaa
     8881 tgctgccggc agttgctcga tgatctcttt ctcgtcgatg cgcagttggt gatgacgggt
     8941 gccgtagtgc ttggcaatca ggtccgaata ttggaactcg tcaccgcgct cgccgccggc
     9001 atcctggaaa ccaatggaga acgtggacag gtcttcaaca ccaacttcgc gcaacagacc
     9061 caccagcatg ctcgaatcca ccccgccgga aagcagcacg ccgacatcca cggcggcgcg
     9121 ctggcgaatg gcgaccgctt cacgggtgct gtcgagcacg cggtcgatcc agtcttccag
     9181 gttcaggtgc tgttcgtcgg cccggggacc gtagggcagg gtccaccagg ttttctgctc
     9241 ggtgctgccg tcggcttcga tccgcatcca ggtggcgggc ggcatttttt caatgccggc
     9301 cagcaaggtg cgaggcgccg ggaccaccgc gtggaaattc aggtaatggt tgagcgccac
     9361 cgggtcgagt acggggttga tatcaccgcc cttgagcagt gccggcaacg ccgaggcgaa
     9421 acgcagccgc tggccggtgc gcgacaggta cagcggcttg acgccgaggc ggtcgcgggc
     9481 gatgaacagc cgcttggcat cgcgctccca gatggcgaac gcgaacatgc cgttgagctt
     9541 gggcagcagc gcttcgcccc aagcgtggta gcccttgagc agcacttcgg tgtcgccacc
     9601 ggaatagaag gtgtagccca ggccttcgag ttcagtgcgc agttcggggt agttgtagat
     9661 cgcgccgttg aaagccaggg acaggcccag ttgattgtcg atcatcggct gggccgagcc
     9721 gtccgacaga tccatgattt tcaggcgccg atggcccagg gcaatcggcc cctggctatg
     9781 aaagccccag gcgtcggggc cgcgtggggc caggtgatgg gtgattcgct ctacggccgc
     9841 aaggtccgca ggttgttgat cgaaacgtaa ctctccagct aatccgcaca taagtcctta
     9901 ccggtttttc cgttggggag gggtcaagca gcacgcgccg acatggcggg taccctgaaa
     9961 ctgaccgggg ggattgctgt gagttttaga tcgatgcgtt ataaggcgac gggtggcggc
    10021 cgcttggtct gccgtataac tcaaggatat gtgggagcga gcctgctcgc gatcgcagtg
    10081 tgtcagtcaa cccaggtacc atctgagcca ccgcgatcgc gagcaggctc gctcccacag
    10141 gatttgtggt gggagcaaaa atcggcgcta ggccttgccc cgaatcaatg cccgcaacgc
    10201 aaaccggttc ggatggcagg cctcggccac gctgcggggc agtggcagcg gttcgttgtc
    10261 cagccaggcg gcgatcagtt cgcccgatag gggcgcggtg atcaggccgc gggaaccgtg
    10321 accgctgttg atgtacaggc catcgagcca cggacagggg gtatccggca cctggcgggc
    10381 gtcctttccc agcgctgcat aagcctcggt aaaggcctgg cggtcggcca acggtccgac
    10441 gatcggcagg taatccgggc tggtgcaacg gaacgccgcg cggccttcga ggtgttgcgg
    10501 gtccagggtg gcggcgttca ggcgctccac caggtcttgg gaaatttctt cgagcatccg
    10561 caggttgccg gcgtgctcgg cggcggtggg ggtcaggtcg tcgctgttga agtcgaaact
    10621 ggcgcccaga gtgtgttcgc ccagccgtgg cggggccaca taaccttcgg cgcaaaccac
    10681 ggttgccagg ctctggctgc gggtggtttg cggcaggcgg gtgatttgcc cgcgaatgcg
    10741 cttgagcggc aactcggcgg ccggttcgaa acgcttgatc tcggccgcgc tggcgaggat
    10801 cgccaccggc gcactggcca ggcagcgttc gccgtcccat gcctgccatt ggccgtcgat
    10861 tcggcgcagt tgcagcactt catgatgggg ttgcacatca atccctggct gcgaggcttg
    10921 ccagcgacac aacgccggcg gatgcaccca accaccctcg ggataaaaca agccaccaca
    10981 ggccaggtcg atgccggacc gaacctgcgc ctctgactga tccagggtgt gcagcaaatc
    11041 ccttgggaac gcctcggcca gttgcgcctg acgctcggct tccttgccgt tgaaggccaa
    11101 ttgcaagacg ccgcaggcgt cccagtcaac gccgcgttgc agttgttcga gcacgcgccg
    11161 ggtgtagccg aagccgctga ggatcatctg cgataaagcg gtgccgtggg ccgacagctt
    11221 gaggtacagc acgccctggg ggttgccgga ggcttcctcg gccaacccgg catgacgctc
    11281 cagcagcgtc acctgccaac cgcgggcggc gaggctggcc gcgctggcgc aaccggccag
    11341 gccgccgccg atcaccagtg cccggcgctc gccgatcaga gtggtcgggc gggcgtacca
    11401 gggttttgcc ggggctggtg cgggtgtctg ctccggccag ccaagaaaca cgccacgaag
    11461 gatttcccat ttatggccga tgcctggcgt gcgcttcatc ttgaagcccg ccgcgttcag
    11521 cgatcgacgg acccaaccgg tgctggtgaa ggtgctgagg gtggcgtcgg gtgcggccag
    11581 ccgggccagt tcggcgaaca gctcggcggt ccacatctcg gggttcttcg ccggggcgaa
    11641 gccatccagg aaccaggcgt cgatctgccc gtccagttgc ggcaactgct ccagggcatc
    11701 gccgatcaac aaggtcagtg tcactcgtcc acccgccaaa gtcagccgct ggaagccctg
    11761 gtggaccgcg acgtactgct caagcaattg ttccgcctga tgcttgagtt gcggccacag
    11821 ttccagtgcc cggcgcaggt cccgggggct caggggatat ttttcgacgc tgacgaaatg
    11881 cagccgcgcc ccggtcggtg cgcactgctc gaacaactgc caggcgcaga ggaaattcaa
    11941 gccggtgcca aatccggttt cgccgatcac cagccgctcg tcatcggcca gggccgcgaa
    12001 gcgctcggcc agattgttct gctcaaggaa cacataacgg gtttcgtcca ggcccgactg
    12061 gtcggaaaaa tacacatcat cgaacacccg cgagcgcggg cgcccctggt catcccagtc
    12121 gagttgggcg tgttgctgga tgggcgtcat ggcaggctcg gtcaaaactg agcggccatt
    12181 ctagccgatc ggtatgggct tgcttgaccc atcgcaatag agcgcgcatc tggatggaat
    12241 ctgctgcaca gggccgcatc caatccgcta gtcttggccc atccccggaa ggagctgccc
    12301 atgtttgaat ccgctgaaat cggtcatgcc attgataaag acacctttga ggccgaggta
    12361 ccggccctgc gtgaggcgct gctggaggcg cagttcgagt tgcagcagca gggccggttt
    12421 ccggtcatcg tgctgatcaa cggcatcgaa ggcgcgggca agggcgagac ggtgaagttg
    12481 ctcaacgagt ggatggaccc gcggctgatc gaagtgcgca ccttcgacca gcagaccgac
    12541 gaggaactgg cgcggccacc ggcctggcgt tattggcgga tgctgccggc gaaggggcgc
    12601 atggggattt tcttcggcaa ctggtacagc cagatgctgc agggccgggt ccatggcgag
    12661 ttcaaggacc cgcggctcga ccaggcgatc gccggtgccg agcgcctgga aaaaatgctc
    12721 tgtgacgaag gcgcgctgat cttcaagttc tggttccacc tgtccaagaa acagatgaag
    12781 gcccggctca aggggctcaa ggatgatccg ctgcacagct ggcgcatcag cccgctggac
    12841 tggcagcagt cccagaccta cgacaagttc gtcaagtacg gtgagcgggt gctgcgccgc
    12901 accagtcgcg attacgcacc gtggcatgtg atcgaaggca tggacagttg ttatcgcagc
    12961 ctcaccgtcg gacggatcct gctcgacggc ttgcgccagg ccctggaccg gtcgaaggtc
    13021 aagccgcaaa aggtcagtgt ggcgccgctg ccggagttgg atggccagat caccttgctc
    13081 gacagcctgg acatgacccg gcgcctggac aaggccgact acgaagaaca gctgatcacc
    13141 gagcaggcgc gcttcgctgg cctgctgcgg gacaaacgca tgcgccagca tgccctggtg
    13201 gcggtgttcg aaggcaatga cgcggcgggc aagggcgggg cgatccgacg ggtcacggcg
    13261 gccctggacc cgcgccaata cagcatcgtg ccgattgccg cacccacgga agaagagcgc
    13321 gcccaccctt acatgtggcg attctggcgg catattcccg cgcgcggcaa gttcaccatg
    13381 ttcgaccgct cctggtacgg ccgggtgctg gtggagcggg tcgaaggctt ttgcagccag
    13441 gccgactggc tgcgggccta cggtgaaatc aacgacttcg aggagcagct tgccgatgcc
    13501 ggcgtggtgg tggtcaagtt ctggctggcc atcgacaagg aaacgcagct ggagcgtttc
    13561 caggagcgtg aggacatccc gttcaagcgt ttcaagatca ccgaggatga ctggcgcaac
    13621 cgcgacaagt gggacgccta ccgcgccgcg gtgtgcgaca tggtcgaccg caccagcact
    13681 gagatttccc cttggacatt ggtggaagcc aacgacaagc gctgggcgcg ggtcaaggtg
    13741 ttgcgcaccc tcaaccaggc gctggaggcg gctttcgagc gcagcgcacg acaggctcgc
    13801 aagaagaagc gctaggacga tgagcacgca tacgcgaggt gaatgattgt cgcggtcggt
    13861 tatgcagtgg atctatgctc gattcactct caaccgacta caacaatgag gtacagccat
    13921 gcgtgaagtg gtgatcgtcg acagcgtacg gaccggcctg gccaagtcct ttcgcggcaa
    13981 gttcaacatg acccgtccgg acgacatggc ggctcactgc gtcaacgccc tgctggcgcg
    14041 caatgacatc aacccggcca gtgtcgagga ctgcatcgtc ggggccgggt ccaatgaagg
    14101 cgcccagggt tacaacattg ggcgcaacgt ggcggtgctc tcgcaattgg gcatcggcac
    14161 cgccggcatg accctcaacc gtttctgttc ctcgggcctg caagccatcg ccatcgcggc
    14221 caaccagatc gcttccggtt gcagcgacat catcgtggcc ggcggcgtgg agtccatcag
    14281 cctgacgatg aaaagcgtca acaccgacaa cctgatcaac ccgctgctca aggagcaggt
    14341 gcccgggatc tatttcccca tgggccagac ggccgagatc gtcgcccgcc gttaccaggt
    14401 cagccgcgaa gagcaggacc gctacgcctt gcagagccag atgcgcaccg ccaaggccca
    14461 ggcggccggg ttgttcgatg acgaaatcat cccgatggcg gtcaaatacc gggtcgagga
    14521 caagcagacc ggcgcggtgc agattctcga tggcgtggtc gatcgcgatg attgcaaccg
    14581 cccggacacc acctacgaga gcctggccgg cctgaaaccg gtgtttgccg aagacggatc
    14641 ggtgacggcg ggcaactcgt cgcagttgtc cgacggggcc tcgatgacct tggtgatgag
    14701 cctggaaaaa gccttggcgc tggggctcaa gcccaaggcg tttttccgtg gtttcaccgt
    14761 ggccggttgc gagccggacg agatgggcat cggcccggtg ttttcagtgc ccaagctgct
    14821 caaggccaag ggcttgcaga ttgccgatat cgacctgtgg gaactcaacg aggcgtttgc
    14881 ctcccagtgc c
//
