3300025503_8 - 4 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

c00006_3300025.. (original name was: 3300025503.a:Ga0209012_1000012)

Region	Type	From	To	Most similar known cluster		Similarity
Region 6.1	NRPS,T1PKS	144,882	207,225

c00010_3300025.. (original name was: 3300025503.a:Ga0209012_1000036)

Region	Type	From	To	Most similar known cluster		Similarity
Region 10.1	betalactone	48,823	76,040

c00015_3300025.. (original name was: 3300025503.a:Ga0209012_1000251)

Region	Type	From	To	Most similar known cluster		Similarity
Region 15.1	bacteriocin	75,568	81,969

c00072_3300025.. (original name was: 3300025503.a:Ga0209012_1001598)

Region	Type	From	To	Most similar known cluster		Similarity
Region 72.1	T3PKS	1	22,684

Region	Type	From	To	Similarity
Region 6.1	NRPS,T1PKS	144,882	207,225
Region 10.1	betalactone	48,823	76,040
Region 15.1	bacteriocin	75,568	81,969
Region 72.1	T3PKS	1	22,684

No secondary metabolite regions were found in these records:: c00001_3300025.. (original name was: 3300025503.a:Ga0209012_1013185); c00002_3300025.. (original name was: 3300025503.a:Ga0209012_1010405); c00003_3300025.. (original name was: 3300025503.a:Ga0209012_1006318); c00004_3300025.. (original name was: 3300025503.a:Ga0209012_1004279); c00005_3300025.. (original name was: 3300025503.a:Ga0209012_1000368); c00007_3300025.. (original name was: 3300025503.a:Ga0209012_1001167); c00008_3300025.. (original name was: 3300025503.a:Ga0209012_1001562); c00009_3300025.. (original name was: 3300025503.a:Ga0209012_1011482); c00011_3300025.. (original name was: 3300025503.a:Ga0209012_1000538); c00012_3300025.. (original name was: 3300025503.a:Ga0209012_1001194); c00013_3300025.. (original name was: 3300025503.a:Ga0209012_1000515); c00014_3300025.. (original name was: 3300025503.a:Ga0209012_1005420); c00016_3300025.. (original name was: 3300025503.a:Ga0209012_1000238); c00017_3300025.. (original name was: 3300025503.a:Ga0209012_1003280); c00018_3300025.. (original name was: 3300025503.a:Ga0209012_1000176); c00019_3300025.. (original name was: 3300025503.a:Ga0209012_1000124); c00020_3300025.. (original name was: 3300025503.a:Ga0209012_1005110); c00021_3300025.. (original name was: 3300025503.a:Ga0209012_1008408); c00022_3300025.. (original name was: 3300025503.a:Ga0209012_1001487); c00023_3300025.. (original name was: 3300025503.a:Ga0209012_1002046); c00024_3300025.. (original name was: 3300025503.a:Ga0209012_1000203); c00025_3300025.. (original name was: 3300025503.a:Ga0209012_1000397); c00026_3300025.. (original name was: 3300025503.a:Ga0209012_1001043); c00027_3300025.. (original name was: 3300025503.a:Ga0209012_1010433); c00028_3300025.. (original name was: 3300025503.a:Ga0209012_1001315); c00029_3300025.. (original name was: 3300025503.a:Ga0209012_1000021); c00030_3300025.. (original name was: 3300025503.a:Ga0209012_1006908); c00031_3300025.. (original name was: 3300025503.a:Ga0209012_1000527); c00032_3300025.. (original name was: 3300025503.a:Ga0209012_1002689); c00033_3300025.. (original name was: 3300025503.a:Ga0209012_1000458); c00034_3300025.. (original name was: 3300025503.a:Ga0209012_1002291); c00035_3300025.. (original name was: 3300025503.a:Ga0209012_1000557); c00036_3300025.. (original name was: 3300025503.a:Ga0209012_1000072); c00037_3300025.. (original name was: 3300025503.a:Ga0209012_1000166); c00038_3300025.. (original name was: 3300025503.a:Ga0209012_1001524); c00039_3300025.. (original name was: 3300025503.a:Ga0209012_1011303); c00040_3300025.. (original name was: 3300025503.a:Ga0209012_1002088); c00041_3300025.. (original name was: 3300025503.a:Ga0209012_1013572); c00042_3300025.. (original name was: 3300025503.a:Ga0209012_1005394); c00043_3300025.. (original name was: 3300025503.a:Ga0209012_1000177); c00044_3300025.. (original name was: 3300025503.a:Ga0209012_1004944); c00045_3300025.. (original name was: 3300025503.a:Ga0209012_1000288); c00046_3300025.. (original name was: 3300025503.a:Ga0209012_1001258); c00047_3300025.. (original name was: 3300025503.a:Ga0209012_1000596); c00048_3300025.. (original name was: 3300025503.a:Ga0209012_1000693); c00049_3300025.. (original name was: 3300025503.a:Ga0209012_1000402); c00050_3300025.. (original name was: 3300025503.a:Ga0209012_1000040); c00051_3300025.. (original name was: 3300025503.a:Ga0209012_1005084); c00052_3300025.. (original name was: 3300025503.a:Ga0209012_1005666); c00053_3300025.. (original name was: 3300025503.a:Ga0209012_1008348); c00054_3300025.. (original name was: 3300025503.a:Ga0209012_1002625); c00055_3300025.. (original name was: 3300025503.a:Ga0209012_1000134); c00056_3300025.. (original name was: 3300025503.a:Ga0209012_1000164); c00057_3300025.. (original name was: 3300025503.a:Ga0209012_1008649); c00058_3300025.. (original name was: 3300025503.a:Ga0209012_1004302); c00059_3300025.. (original name was: 3300025503.a:Ga0209012_1001392); c00060_3300025.. (original name was: 3300025503.a:Ga0209012_1000213); c00061_3300025.. (original name was: 3300025503.a:Ga0209012_1008264); c00062_3300025.. (original name was: 3300025503.a:Ga0209012_1000735); c00063_3300025.. (original name was: 3300025503.a:Ga0209012_1000056); c00064_3300025.. (original name was: 3300025503.a:Ga0209012_1001311); c00065_3300025.. (original name was: 3300025503.a:Ga0209012_1001214); c00066_3300025.. (original name was: 3300025503.a:Ga0209012_1001117); c00067_3300025.. (original name was: 3300025503.a:Ga0209012_1000244); c00068_3300025.. (original name was: 3300025503.a:Ga0209012_1001666); c00069_3300025.. (original name was: 3300025503.a:Ga0209012_1003676); c00070_3300025.. (original name was: 3300025503.a:Ga0209012_1002512); c00071_3300025.. (original name was: 3300025503.a:Ga0209012_1014402); c00073_3300025.. (original name was: 3300025503.a:Ga0209012_1000841); c00074_3300025.. (original name was: 3300025503.a:Ga0209012_1006118); c00075_3300025.. (original name was: 3300025503.a:Ga0209012_1000048); c00076_3300025.. (original name was: 3300025503.a:Ga0209012_1002473); c00077_3300025.. (original name was: 3300025503.a:Ga0209012_1001794); c00078_3300025.. (original name was: 3300025503.a:Ga0209012_1000055); c00079_3300025.. (original name was: 3300025503.a:Ga0209012_1001725); c00080_3300025.. (original name was: 3300025503.a:Ga0209012_1013528); c00081_3300025.. (original name was: 3300025503.a:Ga0209012_1001209); c00082_3300025.. (original name was: 3300025503.a:Ga0209012_1012878); c00083_3300025.. (original name was: 3300025503.a:Ga0209012_1001238); c00084_3300025.. (original name was: 3300025503.a:Ga0209012_1008901); c00085_3300025.. (original name was: 3300025503.a:Ga0209012_1000559); c00086_3300025.. (original name was: 3300025503.a:Ga0209012_1001820); c00087_3300025.. (original name was: 3300025503.a:Ga0209012_1002545); c00088_3300025.. (original name was: 3300025503.a:Ga0209012_1009820); c00089_3300025.. (original name was: 3300025503.a:Ga0209012_1000964); c00090_3300025.. (original name was: 3300025503.a:Ga0209012_1001158); c00091_3300025.. (original name was: 3300025503.a:Ga0209012_1001475); c00092_3300025.. (original name was: 3300025503.a:Ga0209012_1000117); c00093_3300025.. (original name was: 3300025503.a:Ga0209012_1002348); c00094_3300025.. (original name was: 3300025503.a:Ga0209012_1000965); c00095_3300025.. (original name was: 3300025503.a:Ga0209012_1003002); c00096_3300025.. (original name was: 3300025503.a:Ga0209012_1000874)

Compact view

c00006_3300025.. - Region 1 - NRPS,T1PKS

Download region GenBank file

Location: 144,882 - 207,225 nt. (total: 62,344 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 144881 - 207225:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X) + (X) + (pk - ser - X) + (asn)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg6_173

Search NORINE for peptide: strict or relaxed

AMP-binding (459..864): asn

NRPSPredictor2: asn

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asp

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGhVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 90% (moderate)

ctg6_174

Search NORINE for peptide: strict or relaxed

PKS_AT (546..842): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; Methylmalonyl-CoA: 70.8%; Ethylmalonyl-CoA: 66.7%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 126.7
Malonyl-CoA: 118.1
Methoxymalonyl-CoA: 111.2
Isobutyryl-CoA: 103.7
Ethylmalonyl-CoA: 100.1
Benzoyl-CoA: 71.4
2-Methylbutyryl-CoA: 70.8
trans-1,2-CPDA: 69.3
Propionyl-CoA: 63.6
Acetyl-CoA: 55.2
inactive: 52.5
fatty_acid: 52.2
CHC-CoA: 44.2
3-Methylbutyryl-CoA: 34.0

AMP-binding (1538..1938): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHISLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

AMP-binding (2602..3005): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DaTKLGhcGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 70% (weak)

ctg6_175

Search NORINE for peptide: strict or relaxed

AMP-binding (11..415): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: gFfpfAqaiK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 30% (weak)

ctg6_176

Search NORINE for peptide: strict or relaxed

AMP-binding (506..909): X

NRPSPredictor2: asp, asn, glu, gln, aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DgedIGSIaK
Nearest Stachelhaus code:: orn
Stachelhaus code match:: 60% (weak)

c00010_3300025.. - Region 1 - betalactone

Download region GenBank file

Location: 48,823 - 76,040 nt. (total: 27,218 nt) Show pHMM detection rules used

betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

c00015_3300025.. - Region 1 - bacteriocin

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Location: 75,568 - 81,969 nt. (total: 6,402 nt) Show pHMM detection rules used

Region on contig edge.

bacteriocin: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

c00072_3300025.. - Region 1 - T3PKS

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Location: 1 - 22,684 nt. (total: 22,684 nt) Show pHMM detection rules used

Region on contig edge.

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it