LOCUS       c00106_3300025..       11401 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300025528.a:Ga0207867_1002161.
ACCESSION   c00106_3300025..
VERSION     c00106_3300025..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 11:18:56
            Original ID  :: 3300025528.a:Ga0207867_1002161
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11401
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11401
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6146:11399](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6147..11399
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..11401
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11401
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     CDS             complement(3..992)
                     /locus_tag="ctg106_1"
                     /transl_table=11
                     /translation="MKLTRMARGLVLGAIAVLVTGLAMVVVDRTVPASAHGSVTNPPSR
                     NYGCWERWGHDHLNPAMAEIDPMCWQAWQANPNTMWNWNGLYRENVGGNHQAVIPDGQL
                     CSGGLTQGGLYASLDAVGPWTAKPMPNVFTLTLTDGARHGADYLLIYITKQGFDPTTQP
                     LTWDSLELVLRTGSYPPTGLYEAQVDAGNRTGRHVVYTIWQASHLDQPYYLCSDVIFGG
                     GGTPPTTPPTTPPTTPPTTPPTTPPTTPPTTPPTTPPAGAGCTATYRTTSQWPGGFNAE
                     VTVQAGNAAISGWTVTWTWPDGQSISSSWNASITTNGSTVTATNVGYNG"
     CDS             1390..3306
                     /gene_functions="other (smcogs) SMCOG1037:heavy metal
                     translocating P-type ATPase (Score: 469.9; E-value:
                     2.5e-142)"
                     /gene_kind="other"
                     /locus_tag="ctg106_2"
                     /transl_table=11
                     /translation="VGRFGGGATGRWRRWRVAAPLVVLTVVVLVGAGLWLAGQRREAYG
                     SWAAVAVATLVVTLRWLVRSVRHHRIGVDVIATLAMISSLVAREYLAAAVVALMLATGH
                     TLESYAQGRAVRDLRALLARAPRTARRRDPGGGTQVVDADLVRRGDRLLVGPGDVVPVD
                     GLAEEPATLDESVVTGESRLVQRRPGERVASGVVNAGAAFGLRAAATAGESTYAGIVRL
                     AEAANTARAPTVRLADRYAAAFVPFTLALAAIAWGLSGQFVRAVAVLVVATPCPLLLAT
                     PVAIVSGLSRAARHGVLVRDGGSLESLGRARTLLLDKTGTLTAGRPEVADVVTPAGGDR
                     DELLRLAASVEQLSSHVLAAAVVRAAGERDLRLAVPERVTEEAGRGVSGRVEGRLVRVG
                     QHTAGLPDWAVREQRHAESDGLSVVWVGLDGALAGAVLLRDPVRPDAGETVRRLRAAGF
                     SRVVMLTGDRPEVAERVARVVGVDDVVARCSPQEKVARVRAESERAVTVMVGDGINDAP
                     ALAAAGVGVALGATGARASAEVADAVLSVDRLGRLADAVEIARRSRRIAVHGAVAGMGM
                     AGVAMVVAAFGLLPPVAGAFLQEGIDVAVILNALRALGGGRAPGWRRRATGRPPGDRSS
                     DRG"
     misc_feature    2419..2421
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             3436..4599
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 357.4; E-value:
                     1.6e-108)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg106_3"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 6.4e-35, bitscore:
                     108.8, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 8.4e-29, bitscore:
                     88.2, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.5e-33, bitscore:
                     104.6, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDPMELLAVDSLFTEEERDIRDTVRRFAAERIRPYVAEWYAAGE
                     LPARDLARECGRLGLLGMHLEGYGCAGVGAVAYGLACFELEAADSGVRSLVSVQGSLAM
                     YAIRTFGSEEQRQRWLPAMAAGEAIGCFGLTEPDAGSDPGAMRTSARRDGDDWILNGEK
                     MWITNAAVADVAVVWARTDEGIRGFAVPMDTPGVSTPPVGHKLSLRASVTSALVLQDVR
                     LPGDALLPGAIGLRAPLRCLTEARLGIAFGALGAGYDCLRAALDYAGSREAFGRPIAGF
                     QLTQEKLAEMTRGLVSGLLLAVHVGRLREAGAVTPAQVSLAKLNSCETAIGIARTARTI
                     LGANGVTLEYPVLRHANNLEAVLTYEGTSEVHKLVVGQALTGHAAFR"
     CDS             complement(4679..5533)
                     /locus_tag="ctg106_4"
                     /transl_table=11
                     /translation="MRRVPLALLALAVLLAPATPATASERAVPVPPDRATTVAEVRTAG
                     TTWGPDPATGRMVLTVDESVDETHVRALRAVADRSGALFRREPGRLRPLIAGGQGIYGN
                     VGVRCSLGANVRTGNTYYFVTAGHCANAADVWYADSGRTTLLGLRAGSSFPGNDYGIVR
                     HTGTTSHPGAVYTHPGLLPITGVGTPYVGQAVCRSGATTGVRCGAVTGLNVTVNYAQGT
                     VTGLIRTNICAEPGDSGGPLYSPATGTLFGILSGGSGNCSTGGTTYYQPILEILAAYGV
                     TLA"
     CDS             6147..11399
                     /NRPS_PKS="Domain: PKS_KS(Trans-AT-KS) (658-1104). E-value:
                     1.2e-128. Score: 421.3. Matches aSDomain:
                     nrpspksdomains_ctg106_5_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (1216-1506). E-value: 4.2e-64.
                     Score: 208.5. Matches aSDomain:
                     nrpspksdomains_ctg106_5_PKS_AT.1"
                     /NRPS_PKS="type: PKS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 263.6; E-value:
                     5.4e-80)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg106_5"
                     /sec_met_domain="PKS_KS (E-value: 1.2e-129, bitscore:
                     421.3, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 4.1e-65, bitscore: 208.5,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPALNPRDLVIAISGGGLLEPSPRVVAAARRGGGIGVLDLGRGD
                     TWALTALAQAAESAASVGVRVPAGCAATADDVDRAGRGRVDLVVAPLDTPWPLREIVTR
                     YRVLAEVTSLDEAREAVAAGVHGLVARGMESGGRVSELSSFVLLQQLAAADGLDLPIWV
                     AGGIGPRTAVACLVGGAAGVVLDSQLALMPESETPEDVRNTIRRLDGSETVVVDGHRGV
                     RRGGPRDTDGELLPIGQDGWLAAVFADRWPDTAAAVRALRAVLCEAAEAQQGASEALAE
                     GGPLAEALGIRIPVAQGPMTRVSDEAAFAEAVAADGALPFVALALANADQSRRILGETA
                     ARLGDRPWGVGVLGFAPDEVRTAQLEVIRDIRPACAIIAGGRPPQARALEQEGISTFLH
                     VPSPGLLSQFLRSGARRFVFEGAECGGHVGPRASFPLWEAQLDVLDTYLTDNPDDATEL
                     QVFFAGGIHDARSAAMVAAMAAPLTRRGVRIGILMGTAYLFTEEAVTHEAITPLFHHKV
                     VAATRTALLETAPGHTTRCLPSPFVDDFHALRAELEAAGAENRQIWEQLEVLNVGRLRI
                     ASKGVRRQGDQLVTVDEQTQAAEGLYMAGQVAVLRNAPTTVAALHAEVTSGAGTYHRER
                     VAVLREALAPPAVPAPEPPAPLDVAIIGMSCILPGSPDLDSYWSTILDGVDAITEVPAD
                     RWDVATYYAPEVGPGQAGRISVSKWGGFLDPVPFDAIGYGIPPAALSSIDPTQLLALEA
                     ARRALVDAGYPHDRPGIDHRRTGVVFGAEAGSDMGHAQTLRTMLPAYLGEVPAELEDQL
                     PTVSEDSFPGVLANVIAGRVANRLDLGGPNYTVDAACASSLAALDAACKELVAGDSDLM
                     ICGGADLHNGINDYLMFTSAHALSPTGRCRTFDSTGDGIALGEGVACLVLKRLADAERD
                     GDRIYAVIRGIGASSDGRALGLTAPRAEGQRLALERAYRRSGISPRQVGLVEAHGTGTV
                     VGDRTELETLTRLFDSFGAEPGSCVLGSVKSQIGHTKCAAGLAGVIKATLALHTGIAPP
                     TIHLSRPNPAWNPERSPFVFHTSPRPWLTPAAERHAGVSAFGFGGTNFHAVLSAYPGEE
                     PRHARRVWPAELFCFRGTDRAAAHARIRRTVELLASRDELGRPWPLRDLAAAVPDVSDH
                     RAGPVRVAVVARNHDELATLLRRALAGEHDPAGGLVQPPDDDPGPGRVAFLFPGQGSQR
                     PGALAELFVTFPELRHYLRLGRRWADLLLPPTAFDPDTKRQQEQRVRDTRVAQPVLGIG
                     GLAVDHLLRRLGVRPDLAGGHSYGELVALCVAGALDPADLLELSAERAEAILAAAGDDP
                     GTMAAVSAGAAEVERLLAEAGLAGQVVVANQNAPTQVVISGPTAAVEAAVTALRGKGLS
                     ARQIPVACAFHSPVVAEATDRFAAALAARPVRRPAIDVWSNQTAEPYDGDPDEVRRRLA
                     AQIGAPVRFVDQIESMYAAGARIFVEAGPGQVLTKLVRAVLGDRPHLAVAVEPRPEEGL
                     YGFLLCLAQLACAGVPVQPGWLYHGRVTTPAAILARSDDAARRPMWTVNGQLVRDQFGN
                     TLPGGMTPPRRIKELSMTASNGTAAGGRDSRDELLSEFLRTSRDLIAAQRDVMLAYLGG
                     GREVWSATQQYPPVALPVGNGSAVLTAPASPVIPTSPAVPAPPAGPVSPAPAAAPTSPA
                     PLATPSVLTAAPAHPAPSAPADQPVAAALPDFETAIREVISERTGYPADLIDLD"
     aSDomain        8121..9458
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg106_5_PKS_KS.1"
                     /evalue="1.20E-128"
                     /label="ctg106_5_PKS_KS.1"
                     /locus_tag="ctg106_5"
                     /protein_end="1104"
                     /protein_start="658"
                     /score="421.3"
                     /tool="antismash"
                     /translation="VAIIGMSCILPGSPDLDSYWSTILDGVDAITEVPADRWDVATYYA
                     PEVGPGQAGRISVSKWGGFLDPVPFDAIGYGIPPAALSSIDPTQLLALEAARRALVDAG
                     YPHDRPGIDHRRTGVVFGAEAGSDMGHAQTLRTMLPAYLGEVPAELEDQLPTVSEDSFP
                     GVLANVIAGRVANRLDLGGPNYTVDAACASSLAALDAACKELVAGDSDLMICGGADLHN
                     GINDYLMFTSAHALSPTGRCRTFDSTGDGIALGEGVACLVLKRLADAERDGDRIYAVIR
                     GIGASSDGRALGLTAPRAEGQRLALERAYRRSGISPRQVGLVEAHGTGTVVGDRTELET
                     LTRLFDSFGAEPGSCVLGSVKSQIGHTKCAAGLAGVIKATLALHTGIAPPTIHLSRPNP
                     AWNPERSPFVFHTSPRPWLTPAAERHAGVSAFGFGGTNFHAVLSAYPG"
     aSModule        8121..10664
                     /domains="nrpspksdomains_ctg106_5_PKS_KS.1"
                     /domains="nrpspksdomains_ctg106_5_PKS_AT.1"
                     /incomplete
                     /locus_tags="ctg106_5"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       8664..8711
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg106_5_0001"
                     /evalue="4.50E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="ctg106_5"
                     /protein_end="855"
                     /protein_start="839"
                     /score="15.7"
                     /tool="antismash"
                     /translation="GPNYTVDAACASSLAAL"
     CDS_motif       9087..9131
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg106_5_0002"
                     /evalue="2.00E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="ctg106_5"
                     /protein_end="995"
                     /protein_start="980"
                     /score="10.7"
                     /tool="antismash"
                     /translation="VEAHGTGTVVGDRTEL"
     CDS_motif       9192..9236
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg106_5_0003"
                     /evalue="4.50E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="ctg106_5"
                     /protein_end="1030"
                     /protein_start="1015"
                     /score="9.9"
                     /tool="antismash"
                     /translation="GSVKSQIGHTKCAAGL"
     CDS_motif       9792..9842
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg106_5_0004"
                     /evalue="4.60E-04"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="ctg106_5"
                     /protein_end="1232"
                     /protein_start="1215"
                     /score="12.9"
                     /tool="antismash"
                     /translation="FLFPGQGSQRPGALAELF"
     aSDomain        9795..10664
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg106_5_PKS_AT.1"
                     /evalue="4.20E-64"
                     /label="ctg106_5_PKS_AT.1"
                     /locus_tag="ctg106_5"
                     /protein_end="1506"
                     /protein_start="1216"
                     /score="208.5"
                     /specificity="Minowa: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="consensus: mal"
                     /tool="antismash"
                     /translation="LFPGQGSQRPGALAELFVTFPELRHYLRLGRRWADLLLPPTAFDP
                     DTKRQQEQRVRDTRVAQPVLGIGGLAVDHLLRRLGVRPDLAGGHSYGELVALCVAGALD
                     PADLLELSAERAEAILAAAGDDPGTMAAVSAGAAEVERLLAEAGLAGQVVVANQNAPTQ
                     VVISGPTAAVEAAVTALRGKGLSARQIPVACAFHSPVVAEATDRFAAALAARPVRRPAI
                     DVWSNQTAEPYDGDPDEVRRRLAAQIGAPVRFVDQIESMYAAGARIFVEAGPGQVLTKL
                     VRAVLGDRPH"
     CDS_motif       10032..10148
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg106_5_0005"
                     /evalue="2.50E-10"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ctg106_5"
                     /protein_end="1334"
                     /protein_start="1295"
                     /score="32.3"
                     /tool="antismash"
                     /translation="GVRPDLAGGHSYGELVALCVAGALDPADLLELSAERAEAI"
ORIGIN
        1 gcgccgttgt aaccgacgtt cgtggcggtc acggtcgatc cgttcgtggt gatcgaggcg
       61 ttccacgagc tggagatgct ctggccgtcg ggccaggtcc aggtcaccgt ccacccggag
      121 atggcggcgt tgccggcctg gaccgtgacc tcggcgttga agccgccggg ccactggctc
      181 gtcgtccggt acgtcgcggt gcagccggcg ccggccggcg gggtcgtcgg aggcgtcgtc
      241 ggcggggtgg tgggcggagt ggtgggcggg gtggtgggcg gagtggtggg cggggtcgtg
      301 ggcggagtgg tgggcggggt gccgccgcca ccgaagatca cgtcactgca caggtagtac
      361 ggctggtcga ggtggctggc ctgccagatg gtgtagacga cgtgccgccc ggtgcggttg
      421 cccgcgtcca cctgggcctc gtacagcccg gtgggcgggt agctgccggt gcgcagcacc
      481 aactcgaggc tgtcccaggt gagcggctgg gtggtcgggt cgaagccctg cttggtgatg
      541 tagatcagca ggtagtcggc accgtgccga gccccgtcgg tcagggtcag cgtgaagacg
      601 ttcggcatcg gcttcgccgt ccagggaccg accgcgtcga gcgaggcgta cagcccgccc
      661 tgggtgaggc cgccgctgca gagctgcccg tccgggatga ccgcctggtg gttgccaccg
      721 acgttctcgc ggtacaggcc gttccagttc cacatcgtgt tcgggttggc ctgccaggcc
      781 tgccaacaca tcgggtcgat ctcggccatg gcggggttga ggtgatcgtg accccagcgc
      841 tcccagcatc cgtagtttcg ggagggcggg ttggtgaccg acccgtgcgc cgaggcggga
      901 acggtccggt cgacgacgac catcgcgagc ccggtgacga ggaccgcgat cgcgccgagc
      961 acgaggccgc gcgccattcg tgtgagcttc atcgatactc cagcattccg tcgacgacgg
     1021 tgccgctcga cgggatgccc aggcccgcga ggaacacacg ccggtcgaca tgaaggacct
     1081 cggacacgtg ggcagcatgt ggtgctgccc cgcggcggca tggcggctcc cgcgaccatg
     1141 ctactcactc agatccaccg atgtgaattc gccggtggtg cggcccacac ccggtgctca
     1201 cccggtcgtg acgtcctgcg ggtcgacgga tcggcggatc ggcccacgcc gggcgtggcg
     1261 tggtggggac gctggtgggt acgggcctgt cggacgagag cctgccggtg cgcctccggc
     1321 ccggtgcgga tcccactccg cgtgaacccg tcggcacacc gggggcgacg tcgaacgggg
     1381 ggagagaacg tgggccgctt cggtggtggc gcgacgggac gctggcgtcg gtggcgtgtc
     1441 gccgccccgt tggtggtact gacggtggtg gtgctggtcg gcgccggcct gtggctcgcc
     1501 ggacagcggc gcgaggcgta cggatcgtgg gccgcggttg cggtggcgac actggtggtg
     1561 acgctgcgct ggctggtccg gtcggtgcgg caccaccgga tcggcgtcga cgtgatcgcc
     1621 accctggcca tgatcagctc cctggtggcg cgggagtacc tggccgcggc ggtggtggcg
     1681 ctcatgctgg ccaccgggca cacgctggag tcgtacgccc agggcagggc cgtccgggat
     1741 ctgcgtgcgc tgctggcgcg ggcgccccgg acggcgcggc gccgcgaccc gggcggaggg
     1801 acccaggttg tggacgccga cctggtgcgg cgcggtgatc ggctgctcgt gggcccgggt
     1861 gacgtcgtcc cggtggacgg cctcgccgag gagccggcga cgctggacga gtccgtggtg
     1921 accggtgagt cccggttggt gcagcggcgg cccggggaga gggtggccag cggcgtggtc
     1981 aacgcggggg cggcgttcgg cctgcgggcc gcggcgacgg cgggcgagag cacgtacgcc
     2041 ggcatcgtcc ggctggcgga ggcggcgaac acggcgaggg caccgacggt gcggctggcc
     2101 gaccggtacg cggcggcgtt cgtgccgttc accctggccc tggccgcgat cgcgtggggg
     2161 ttgtccggac agttcgtacg ggcggtggcg gtgctggtgg tggcgacgcc gtgtcccctg
     2221 ctgctggcca ccccggtcgc gatcgtctcc ggcctgtccc gggcggcgcg gcacggggtg
     2281 ctggttcgcg acggtggttc gctggagtcg ctgggccgcg cccggaccct gctgctggac
     2341 aagaccggga cgttgacggc cggccgcccg gaggtggccg acgtggtgac cccggcggga
     2401 ggcgaccgcg acgagctgtt acggctggcc gcgtcggtcg agcagttgtc gtcgcacgtg
     2461 ctcgcggcgg cggtcgtacg ggccgccggc gagcgggacc tgcggctggc ggtaccggag
     2521 cgggtgacgg aggaggccgg acggggggtg tccggccggg tcgagggccg gctggtgcgg
     2581 gtggggcaac acactgccgg gttgccggac tgggccgtac gcgagcagcg gcacgcggag
     2641 tcggacggcc tgtcggtggt gtgggtgggc ctggacgggg cgcttgccgg ggcggtgttg
     2701 ctgcgggatc cggtgcggcc ggacgccggg gagacggtac ggcggctccg cgcggccggg
     2761 ttctcccggg tggtcatgct gaccggggac cgtccggagg tcgccgaacg ggtggccagg
     2821 gtggtcgggg tggacgacgt ggtcgcccgg tgctccccgc aggagaaggt cgccagggtc
     2881 cgggcggagt ccgaacgtgc ggtgacggtg atggtcgggg acgggatcaa cgacgcgccc
     2941 gctctggcgg cggccggggt gggggtggcg ctgggcgcca ccggcgcacg ggcgtcggcc
     3001 gaggtcgccg acgccgtgct gtcggtggac cggctgggcc ggctggccga cgcggtggag
     3061 atcgcccgcc gctcccggcg gatcgcggtg cacggcgcgg tcgccgggat gggcatggcg
     3121 ggggttgcca tggtcgtggc cgcgttcggg ctcctccctc cggtggccgg ggcgttcctg
     3181 caggagggca tcgacgtggc cgtgatcctc aacgcgctac gcgctctcgg cggtggtcgg
     3241 gctccggggt ggagacgccg ggcgaccggc cggcctccgg gcgaccgctc ttccgaccgg
     3301 ggataggcgg gacgccgcgg ccggcacggc aggtggccga tcccagtacc ctgtcccgga
     3361 caccatcacc caccaccgcc caccaccgaa acccggcgag cccccgcaca ccgccgagtc
     3421 ctctggagat ccctgatgac cgacccgatg gaactcctcg ctgtcgacag tctcttcacc
     3481 gaggaggagc gcgacatccg ggacaccgta cgccggttcg ccgccgaacg gatccggccg
     3541 tacgtcgccg agtggtacgc cgccggcgag ctgcccgccc gggacctggc ccgggagtgc
     3601 ggccggctcg gcctgctcgg catgcacctg gagggttacg gctgtgccgg cgtcggggcg
     3661 gtcgcctacg gcctggcctg cttcgagctg gaggcggccg actccggtgt ccgcagcctg
     3721 gtgtcggtgc agggctcgtt ggccatgtac gccatccgga ccttcggcag cgaggaacag
     3781 cgccagcggt ggctgccggc gatggcggcc ggcgaggcga tcggctgttt cgggctgacc
     3841 gagccggacg ccggctccga cccgggcgcg atgcgcacct cggctcgccg cgacggggac
     3901 gactggatcc tcaacggcga gaagatgtgg atcaccaatg cggcggtggc cgacgtggcg
     3961 gtggtgtggg cccggaccga cgagggtatc cgcggtttcg ccgtaccgat ggacactccc
     4021 ggggtgagca ccccgccggt cgggcacaag ctgtccctgc gggcctcggt gacctcggcc
     4081 ctggtgctgc aggacgtccg gctgcccggc gacgccctcc tgcccggggc gatcggccta
     4141 cgcgcgcccc tgcggtgcct caccgaggca cggctcggca tcgccttcgg cgctctcggc
     4201 gccgggtacg actgcctgcg cgccgcgctc gactacgccg gcagccggga ggcgttcggg
     4261 cggccgatcg ccggcttcca gctcacccag gagaagctgg ccgagatgac ccggggactg
     4321 gtcagcgggc tgctgttggc cgtccacgtc ggacggctcc gggaggcggg cgccgtgacc
     4381 ccggcccagg tcagcctcgc caagctgaac agctgcgaga ccgcgatcgg catcgcccgc
     4441 accgcccgga cgatcctcgg cgccaacggg gtgacgctgg agtacccggt gctgcggcac
     4501 gccaacaacc tggaggcggt gctgacctac gagggcacca gcgaggtgca caagctggtc
     4561 gtcgggcagg ccctgaccgg gcacgccgcc ttccgctgac cgcccgcggc ggctcgggac
     4621 cggtgaccgg ccacccgcgg cggccgacac cagggttacc ggccgcccgc ggcggccttc
     4681 acgcgagggt gacgccgtac gccgccagga tctccaggat cggctggtag tacgtggtcc
     4741 cgccggtgct gcagttgccg ctgccgccgg acaggatgcc gaagagcgtc ccggtcgccg
     4801 gcgagtagag cggcccgccg ctgtcccccg gttccgcgca gatgttggtg cggatgagcc
     4861 cggtgacggt gccctgggcg tagttcaccg tcacgttcag cccggtcacc gcgccgcagc
     4921 gtacgccggt ggtggcgccg ctgcggcaga cggcctgacc gacgtacggg gtgccgacgc
     4981 cggtgatcgg gagcaggccg gggtgggtgt acaccgcgcc ggggtggctc gtggtgccgg
     5041 tgtggcgcac gatgccgtag tcgttgccgg ggaagctgct gccggcgcgg aggcccagca
     5101 gggtggttcg gccgctgtcg gcgtaccaga cgtcggcggc gttggcgcag tgcccggcgg
     5161 tgacgaagta gtacgtgttc ccggtgcgga cgttcgcccc gagggaacag cgcaccccga
     5221 cgttgccgta gatgccctgt ccgcccgcga tgagcggccg caggcggccg ggctcccggc
     5281 ggaacagtgc cccggaccgg tcggcgaccg cgcgcagtgc ccggacgtgg gtttcgtcga
     5341 cggactcgtc gacggtgagc accattcggc cggtcgccgg atccggtccc cacgtggtgc
     5401 cggcggtacg cacctcggcc acggtggtgg cgcggtcggg cgggacgggg acggcgcgct
     5461 cggacgcggt ggccggggtg gccggcgcca gcagcacggc gagcgcgagg agggcaaggg
     5521 gtacccggcg cataccagac gctcccaatc gttggtggtc gatgtatgtg ccagcatccg
     5581 ccctcgccgg aggcgtttca atccccaacc cgaccggccg ccggcgtcgg gccggccgac
     5641 ccggggtgcg gtcgccctcc gacccgccga gcccggtgca ccggacgagg acggcgcgac
     5701 ccgggagcag atccgaatca attcatactt tggagatagg aatacttctt cgccgggttc
     5761 tgggcccacc agaatgattc cacgttcacc accacgaaag agatagtgac gattgtcact
     5821 cacttagtca tcgttaacat ccgcgtaatg aaaatgcagc gcgaattaac cggtgacacc
     5881 cttcgccgtt cgccgaacgc atcgcccatg atcgggttcg gcaggacgtg gtcctgggca
     5941 cgaaagaagc ttcgcaggtc agccgcacac tgaaaccagg gccatgatca attcagtgaa
     6001 ccgcgacgga tttaactgtg tcgtaacgcg gctcccttac gttattccgg aatccgaaat
     6061 cgaccagtga caatgcgtcg atcctgctct ccgttgttct gaccacctcg gcgatccgag
     6121 accaccgctc acgaagtggg agtccgatga atcctgcact gaacccgcgc gacctggtta
     6181 tcgccatcag cggcggcggc ctgctggagc caagtccccg ggtcgtcgcc gcggcgcgac
     6241 ggggcggcgg aatcggcgta ctcgacctcg gccgcggcga cacctgggca ctcaccgctc
     6301 tcgcccaggc ggcggagtcg gccgcatccg tcggggtacg cgtccccgcc ggatgcgccg
     6361 ccaccgcgga cgacgtcgac cgggccggcc gcggccgggt cgacctcgtc gtcgcgccgc
     6421 tggacacccc ctggccacta cgcgagatcg tcacccgcta ccgggtgctg gccgaggtca
     6481 ccagtctgga cgaggcccgc gaggcggttg cggcgggcgt gcacgggctc gtcgcccggg
     6541 gcatggagtc cggcggacgg gtcagcgagc tcagctcgtt cgtcctgctc cagcagctcg
     6601 ccgcggccga cgggctcgac ctgccgatct gggtggccgg cggcatcgga ccgcgtaccg
     6661 ccgtggcctg cctcgtcggc ggcgccgccg gggtggtgct ggacagccag ctcgccctga
     6721 tgcccgaatc cgagacaccg gaggacgtcc ggaacaccat ccgacgactg gacggctccg
     6781 agaccgtggt cgtcgacggc caccgggggg tacgccgcgg cggcccgcgc gacaccgacg
     6841 gcgaactcct gcccatcggc caggacggct ggctcgccgc cgtcttcgcc gaccgctggc
     6901 ccgacaccgc cgccgcggtc cgcgccctcc gagccgtcct gtgcgaggcg gccgaggcgc
     6961 aacagggcgc gagcgaggcg ctggccgagg gcggcccgct cgccgaggcc ctgggcatcc
     7021 gcataccggt ggcacaggga cccatgaccc gggtcagcga cgaggcggcc ttcgccgagg
     7081 ccgtcgccgc cgacggcgcc ctgccgttcg tcgcgctcgc cctcgccaac gccgaccagt
     7141 cccgccggat cctcggcgag accgccgccc ggctcgggga ccggccctgg ggggttggcg
     7201 tactcggctt cgcacccgac gaggtacgga ccgcccagct ggaggtgatc cgggacatca
     7261 ggcccgcctg cgcgatcatc gccgggggcc ggccgcccca ggcccgggcg ctggagcagg
     7321 aggggatcag caccttcctc cacgtaccct ccccgggact gctgagtcag ttcctccgct
     7381 ccggcgcccg caggttcgtc ttcgaggggg ccgagtgcgg cggccacgtc ggcccccggg
     7441 cgagcttccc gctctgggag gcccagctcg acgtcctcga cacgtacctg accgacaacc
     7501 cggacgacgc caccgagctg caggtcttct tcgcgggcgg gatccacgac gcccggtcgg
     7561 ccgccatggt cgcggcgatg gccgccccgc tcacccgacg cggcgtccgg atcggaatcc
     7621 tgatgggcac cgcctacctc ttcaccgagg aggcggtgac gcacgaggcg atcaccccgc
     7681 tcttccacca caaggtcgtc gccgccaccc ggaccgcgct gctggagacc gcccccgggc
     7741 acaccacccg gtgcctgccc agcccgttcg tcgacgactt ccacgcgctg cgcgcggagc
     7801 tggaggcggc cggggcggag aaccggcaga tctgggagca gctggaggtc ctcaacgtcg
     7861 ggcggctgcg gatcgccagc aagggcgtac gccggcaggg cgaccaactc gtcaccgtgg
     7921 acgagcagac ccaggccgcc gagggtctct acatggccgg ccaggtcgcc gtcctccgga
     7981 acgccccgac caccgtcgcc gcactgcacg ccgaggtgac cagcggggcg ggtacgtacc
     8041 accgcgagcg cgtcgccgtg ctgcgcgagg cgctcgcccc accggccgta cccgcacccg
     8101 agccgccggc cccgctggac gtcgccatca tcgggatgtc ctgcatcctg cccggatccc
     8161 cggacctcga cagctactgg agcaccatcc tcgacggtgt cgacgcgatc accgaggttc
     8221 ccgccgaccg gtgggacgtg gcgacgtact acgccccgga ggtcgggccc gggcaggcgg
     8281 gccggatcag cgtctccaag tggggcggct tcctcgaccc ggtgccgttc gacgcgatcg
     8341 ggtacggcat cccaccagcg gcactgagca gcatcgaccc gacccagctc ctcgccctgg
     8401 aagcggcgcg ccgcgccctg gtcgacgccg ggtaccccca cgaccgcccg gggatcgacc
     8461 accgccggac cggggtggtc ttcggcgccg aggcgggcag cgacatggga cacgcccaga
     8521 ccctgcgcac catgctcccc gcctacctcg gtgaggtgcc ggcggagctc gaggaccagc
     8581 ttcccaccgt cagcgaggac agcttcccgg gggtactggc caacgtcatc gccggccggg
     8641 tcgccaaccg gctcgacctg ggcggcccca actacaccgt cgacgccgcc tgcgcctcct
     8701 ccctggccgc gctcgacgcg gcctgcaagg agctcgtcgc cggtgacagc gacctgatga
     8761 tctgcggcgg cgccgacctg cacaacggca tcaacgacta cctgatgttc acctccgcac
     8821 acgcgctgag cccgaccggg cggtgccgga ccttcgacag caccggcgac ggcatcgccc
     8881 tcggggaggg ggtggcctgt ctggtgctca agcggctggc cgacgccgag cgggacggcg
     8941 accggatcta cgcggtgatc agggggatcg gcgcctccag cgacgggcgg gccctcggcc
     9001 tgaccgcgcc gcgggccgag gggcagcgcc tggcgctgga gcgggcgtac cggcgcagcg
     9061 gcatctcgcc ccggcaggtc ggcctcgtcg aggcgcacgg caccggcacg gtcgtcggcg
     9121 accgcaccga gctggagacg ctgaccaggc tcttcgactc cttcggcgcg gagccgggaa
     9181 gctgcgtcct cggttcggtg aagtcgcaga tcgggcacac caagtgcgcg gccggactgg
     9241 ccggagtgat caaggcgacc ctggcgctgc acaccgggat cgcacccccc acaatccacc
     9301 tcagccgccc gaacccggcc tggaaccccg aacgcagccc gttcgtcttc cacaccagcc
     9361 cccggccgtg gctgaccccc gccgccgagc gccacgccgg agtcagcgcg ttcggcttcg
     9421 gcggcaccaa cttccacgcc gtactcagcg cctaccccgg cgaggagcca cggcacgccc
     9481 gccgggtctg gccggccgag ttgttctgct tccggggcac cgaccgggcc gccgcgcacg
     9541 cccggatccg gcgtaccgtc gagctgctcg ccagccggga cgaactgggc cggccgtggc
     9601 cgctccggga cctggcggcg gccgtacccg acgtgtcgga ccaccgcgcc ggcccggtac
     9661 gggtcgccgt cgtcgcccgc aaccacgacg agctcgccac cctgctgcgt cgggccctgg
     9721 ccggcgagca cgatccggcc gggggtctgg tccagccgcc ggacgacgat cccggcccgg
     9781 gccgggtggc gttcctgttc cccggtcagg gcagtcaacg tccgggcgcc ctcgccgagc
     9841 tcttcgtcac cttccccgaa ctgcgccact acctgcgtct cggccggcgg tgggcggacc
     9901 tgctcctccc gccgaccgcg ttcgacccgg acaccaagcg gcagcaggag cagcgggtcc
     9961 gggacacccg ggtcgcccag ccggtcctcg gcatcggcgg gctcgccgtc gaccacctgc
    10021 tgcgccgact cggcgtccgg cccgacctgg ccggcgggca cagctacggc gaactcgtcg
    10081 cgctctgcgt cgccggcgcc ctcgacccgg cggacctgct cgaactcagt gccgaacgcg
    10141 ccgaggcgat cctcgccgcg gccggggacg acccgggcac catggcggcg gtctcggcgg
    10201 gcgcggccga ggtcgagcgg ctgctggccg aggccgggct ggccggtcag gtggtcgtcg
    10261 ccaaccagaa cgccccgacc caggtggtga tctccgggcc gacggcggcg gtggaggccg
    10321 cggtcaccgc gctgcgcggc aaggggctct ccgcccggca gattcccgtc gcctgcgcct
    10381 tccacagccc ggtggtggcc gaggccaccg accggttcgc cgcggcactc gcggcccgtc
    10441 cggtacgccg gcccgccatc gacgtctggt cgaaccagac cgccgagccg tacgacggcg
    10501 accccgacga ggtacggcgg cggctcgccg cacagatcgg ggcgccggtg cggttcgtcg
    10561 accagatcga gtcgatgtac gccgccggtg cccggatctt cgtcgaggcc ggcccgggtc
    10621 aggttctcac caagctcgtc cgggccgtgc tcggcgaccg gccccacctg gcggtggcgg
    10681 tcgaaccccg tcccgaggag gggctgtacg ggttcctcct ctgcctcgcc cagctcgcct
    10741 gcgccggtgt tccggtccag cccggctggc tgtaccacgg gcgggtcacg accccggccg
    10801 cgatcctggc ccgctcggac gacgccgcac gccgcccgat gtggacggtg aacggccagc
    10861 ttgtccgcga ccagttcgga aacaccctgc ccggtgggat gacgcccccg cgacgcatca
    10921 aggagttgtc gatgaccgca tcgaacggca ccgccgccgg tggccgggac agccgggacg
    10981 agctgctcag cgagttcctg cggaccagcc gggacctcat cgccgcccag cgcgacgtga
    11041 tgctcgccta cctcggcggc ggccgcgagg tctggtcggc cacccagcag tacccgccgg
    11101 tcgccctgcc ggtcggcaac ggctcggcgg tgctgaccgc accggcctcg ccggtgatcc
    11161 ccaccagccc ggcggtgccg gcgccgcccg ccggcccggt gtccccggca cccgcggcgg
    11221 cccccacctc gccggctccc ctggcgaccc cgtcggtcct caccgccgca ccggcccacc
    11281 ccgctccgtc ggcccccgcc gaccagcccg tcgcggcggc gctgcccgac ttcgagacgg
    11341 cgatccgcga ggtgatcagc gagcgcaccg gataccccgc cgacctcatc gacctcgacc
    11401 t
//
