LOCUS       c00146_3300025..        7251 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300025547.a:Ga0209556_1003285.
ACCESSION   c00146_3300025..
VERSION     c00146_3300025..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 12:30:36
            Original ID  :: 3300025547.a:Ga0209556_1003285
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7251
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..7251
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2157:5649](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2158..5649
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..7251
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or
                     TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or
                     TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692
                     or TIGR01193)"
                     /kind="neighbouring"
                     /product="NRPS"
                     /product="bacteriocin"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..7251
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="bacteriocin"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or
                     TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or
                     TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or
                     TIGR01193)"
                     /tool="antismash"
     protocluster    1..6880
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1640:1880](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or
                     TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or
                     TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692
                     or TIGR01193)"
                     /neighbourhood="5000"
                     /product="bacteriocin"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      1641..1880
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or
                     TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or
                     TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692
                     or TIGR01193)"
                     /neighbourhood="5000"
                     /product="bacteriocin"
                     /protocluster_number="2"
     cand_cluster    1..6880
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or
                     TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or
                     TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692
                     or TIGR01193)"
                     /kind="single"
                     /product="bacteriocin"
                     /protoclusters="2"
                     /tool="antismash"
     CDS             2..115
                     /locus_tag="ctg146_1"
                     /transl_table=11
                     /translation="FIVNDGEHGAREAGRLRLEGKDYVLSDGDIMHFRFNV"
     CDS             complement(566..874)
                     /locus_tag="ctg146_2"
                     /transl_table=11
                     /translation="MSSYYLSRNTNDIQGFVAIGMGATQKDSDVNSSISLKTINIPVLD
                     LYGTDDLPGVLETAELRKQAAAHNPQYSQKVIQGANHFFDEMNDELVVAVADWSQQF"
     CDS             complement(983..1324)
                     /locus_tag="ctg146_3"
                     /transl_table=11
                     /translation="MGKKYIVLILGIALVAPGFASDLGKEQRWREQVADSIMDGEEVDV
                     MVDGRGVFGIYTEATNGSNKGMIVVHGTGIHPDWQQVVQPIRVAMTEYGWHTLSIQMPI
                     LHNDAKYEE"
     CDS             1641..1880
                     /gene_functions="biosynthetic (rule-based-clusters)
                     bacteriocin: TIGR03798"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg146_4"
                     /sec_met_domain="TIGR03798 (E-value: 2.7e-09, bitscore:
                     26.1, seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNAFQSFRNAVLEDDDLQEQVISIVNTATANGSGLGDGIATLAK
                     NHGYSITSEEVYAHADFLGQDGDLTDFELEMISG"
     CDS             2158..5649
                     /NRPS_PKS="Domain: CAL_domain (164-481). E-value: 6.7e-90.
                     Score: 293.2. Matches aSDomain:
                     nrpspksdomains_ctg146_5_CAL_domain.1"
                     /NRPS_PKS="Domain: ACP (617-663). E-value: 1.4e-07. Score:
                     23.5. Matches aSDomain: nrpspksdomains_ctg146_5_ACP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (729-906). E-value:
                     2e-14. Score: 45.0. Matches aSDomain:
                     nrpspksdomains_ctg146_5_Condensation_LCL.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     348.4; E-value: 9.3e-106)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg146_5"
                     /sec_met_domain="Condensation (E-value: 2.1e-23, bitscore:
                     71.7, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.9e-83, bitscore:
                     268.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.6e-08, bitscore:
                     23.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTLAEALVCRADNAPSDPAFSFIENDEGQISQLSNAELASWAWC
                     AAQALTEKTRAGQRIVLLAPEGLDFIAGFYACILSGRVVVPTYPPNSSRITRATTRLNL
                     LIRDADPDAILTTQALAARITALVREFGWRHIPVLTVKERPDSACRETAESMLNNIQPR
                     SPAIIQYTSGSTSQPKGVVLSHHNLVNNARGMQAHGAFDSTSVGFSWLPPYHDMGLISG
                     LTLPVCVGYHSVLCAPSRFLGRPASWLESIDRFSATITGGPNFAFDLCVDKIKDQEIEG
                     ISLSSLKAVFNGAEPVRSFTLARFVARFKSFGFNPDSFSPVYGLAETTLMAAGIRAGEP
                     AVARAFDKESLSSGVALPPTGGNPTVSLVSCGTPLVEHAITIHDSESSEPLGPGVVGEI
                     YVEGPSIASGYFRSGDADAPTAFCLSQRYPGEMQFQTGDLGFILDDHLFITGRIKDLII
                     VRGKNLYPQDIELSAADAHPAIDHYRVCAFSIDDGMCEQLAIVCEIKRTHRRNLETTTV
                     TRLIRKAVTQEHNVTPAVVSLVKPGTIPLTTSGKIRRHACRDLFFAKGWNPIYQHATNE
                     GEKNPDSDVLISAGYQRGRSQNLTRQKLKGLSHEDQTQAIKDYLATVVSSLLNLSPQAV
                     VHDRPLIESGVDSLSLVELGHRIRRDLDCAVGLFIEKDLSLDDLVHEILVQLSHDPVSE
                     GLTGVDRGNASNRDIPMSPIHLELLDSGADLERQIVTVYIRLPPQADQNVVKRILSHVL
                     AQHGVFYLRKNSERQHWRFVPSETTSLFSFAVLKAIDLEEEQVKRFSKELDSLVCEPFD
                     LIQGPLVHAVFVDKGPGESGMLVLSFSHTVVDAISLWILSNELEQVWTQRSDTAEIHSP
                     VLDQSGLDWNCYLHAHAQSRVAGQQTHYWMDIKKKINGSLVDLQPRGNREESSLRAISR
                     PHQHPGRLNPFLSLALSDRFASLREQHDVFLTAFLRAWYQASGNALCAVSLESHGRQQM
                     GQWGISGMPVGWFTMHFPVVFELDPSDSIWSSCDKITTAINNVPEGGSGFGLLRYLCCD
                     PEIQTLFSKFPAPLIRFVYRGKMDQRFRDRDAFKILDASVQRPYKAGPSSSDSNEILVF
                     VRHEVGGFSWNIESTPGTRTDWKMPPEEQLVSLMEQALNDGLRPFDKMSAKVAEPR"
     aSDomain        2650..3600
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg146_5_CAL_domain.1"
                     /evalue="6.70E-90"
                     /label="ctg146_5_CAL_domain.1"
                     /locus_tag="ctg146_5"
                     /protein_end="481"
                     /protein_start="164"
                     /score="293.2"
                     /specificity="Minowa: NH2"
                     /tool="antismash"
                     /translation="PAIIQYTSGSTSQPKGVVLSHHNLVNNARGMQAHGAFDSTSVGFS
                     WLPPYHDMGLISGLTLPVCVGYHSVLCAPSRFLGRPASWLESIDRFSATITGGPNFAFD
                     LCVDKIKDQEIEGISLSSLKAVFNGAEPVRSFTLARFVARFKSFGFNPDSFSPVYGLAE
                     TTLMAAGIRAGEPAVARAFDKESLSSGVALPPTGGNPTVSLVSCGTPLVEHAITIHDSE
                     SSEPLGPGVVGEIYVEGPSIASGYFRSGDADAPTAFCLSQRYPGEMQFQTGDLGFILDD
                     HLFITGRIKDLIIVRGKNLYPQDIELSAADAHPAIDH"
     aSModule        2650..4146
                     /domains="nrpspksdomains_ctg146_5_CAL_domain.1"
                     /domains="nrpspksdomains_ctg146_5_ACP.1"
                     /incomplete
                     /locus_tags="ctg146_5"
                     /starter_module
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       2653..2712
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg146_5_0001"
                     /evalue="1.50E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg146_5"
                     /protein_end="185"
                     /protein_start="165"
                     /score="23.8"
                     /tool="antismash"
                     /translation="AIIQYTSGSTSQPKGVVLSHH"
     CDS_motif       3334..3393
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg146_5_0002"
                     /evalue="7.30E-08"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg146_5"
                     /protein_end="412"
                     /protein_start="392"
                     /score="24.8"
                     /tool="antismash"
                     /translation="PGVVGEIYVEGPSIASGYFRS"
     CDS_motif       3505..3567
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg146_5_0003"
                     /evalue="1.10E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg146_5"
                     /protein_end="470"
                     /protein_start="449"
                     /score="14.9"
                     /tool="antismash"
                     /translation="TGRIKDLIIVRGKNLYPQDIEL"
     aSDomain        4009..4146
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg146_5_ACP.1"
                     /evalue="1.40E-07"
                     /label="ctg146_5_ACP.1"
                     /locus_tag="ctg146_5"
                     /protein_end="663"
                     /protein_start="617"
                     /score="23.5"
                     /tool="antismash"
                     /translation="DYLATVVSSLLNLSPQAVVHDRPLIESGVDSLSLVELGHRIRRDL
                     DC"
     aSDomain        4345..4875
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg146_5_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="2.00E-14"
                     /label="ctg146_5_Condensation_LCL.1"
                     /locus_tag="ctg146_5"
                     /protein_end="906"
                     /protein_start="729"
                     /score="45.0"
                     /tool="antismash"
                     /translation="VTVYIRLPPQADQNVVKRILSHVLAQHGVFYLRKNSERQHWRFVP
                     SETTSLFSFAVLKAIDLEEEQVKRFSKELDSLVCEPFDLIQGPLVHAVFVDKGPGESGM
                     LVLSFSHTVVDAISLWILSNELEQVWTQRSDTAEIHSPVLDQSGLDWNCYLHAHAQSRV
                     AGQQTHYWMDIKKKI"
     aSModule        4345..4875
                     /domains="nrpspksdomains_ctg146_5_Condensation_LCL.1"
                     /incomplete
                     /locus_tags="ctg146_5"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       5152..5184
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg146_5_0004"
                     /evalue="3.70E-03"
                     /label="NRPS-E5"
                     /locus_tag="ctg146_5"
                     /protein_end="1009"
                     /protein_start="998"
                     /score="10.2"
                     /tool="antismash"
                     /translation="VGWFTMHFPVVF"
     CDS_motif       5248..5292
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg146_5_0005"
                     /evalue="7.30E-04"
                     /label="NRPS-E6"
                     /locus_tag="ctg146_5"
                     /protein_end="1045"
                     /protein_start="1030"
                     /score="12.2"
                     /tool="antismash"
                     /translation="NVPEGGSGFGLLRYLC"
     CDS             5730..6281
                     /locus_tag="ctg146_6"
                     /transl_table=11
                     /translation="VRAVLYFLGCLSDLDIKWLVSSGRALSFDEGETLVVAGTPLTDVF
                     FLMEGELSVRVGTSGDQEVNRMKYGEFFGEISFLDSRPPSATIVAVTPVRVLAMDRDDI
                     EGKLDRDAEFGARFFRGIGVLLANRIRGLIQHVDESKELDLYADEVAGELDPDLLDTIN
                     LAGRRFDLMLDLFRDSLSRG"
     CDS             6283..7251
                     /locus_tag="ctg146_7"
                     /transl_table=11
                     /translation="LAWKLERGEMSEEKNKASPKPRSIFRAEALDQLSSPEQLEQLLQV
                     TGRKSWITLGTIGVLLGAVLVWSIFGRIPVTVSGTGILIYPRHVMPFQASTAGQLASLN
                     FAVGDRVQAGQVIATISVPEIAQRLEQEITRLERMKARHSTITDLQNQRLSLETEALHR
                     KRAMLKDRIDTAKAMAQALRTKNETYMAKQHTVLNDYLKAQTELEETLGKRYQSFKRLL
                     ESQLTSDEMVLQAYQKLVDVRIKKSDLELEAQQLELKKLETEEAYAEQKNRIAEFTAQL
                     QEISIDETRLKQKGFEEAAELDIQIQDALRNIARLEKSLKKG"
ORIGIN
        1 ctttatcgtc aacgacggag agcacggtgc acgtgaagcg ggcaggttac ggctggaggg
       61 aaaagactac gtcctaagtg atggcgacat catgcatttt cgttttaacg tctgaatcaa
      121 acgtgagcgc gaccggaata tccgggtaag tacgagagcg caacgctcag gctgaccacc
      181 tttgaacagg ccggcctttt caaggtgata tgtcgtacgc ttgaggcgcg gccacgcgtt
      241 tttagcccgt tttaatggtc tttaccttgt tctggaggag atttcgcgct acattcgcgc
      301 acccaccgtg gctatgtagc tcagctggtt agagcacggc attcataatg ccggggtcgg
      361 tggttcaagt ccacccatag ccaccatcct ttcagttagt tatgcctgtt gcgccatgtg
      421 ggcaatgttc cgtggcacaa atatggcaca gcagattccc gcagaccctg gttgaccgga
      481 taaccgtccc accagtgtca cagtcgcatc aggtttggga aactaccgct gctcccgttc
      541 actccgatgt tttgcgcaaa cccgactaaa actgctggct ccagtctgcc accgccacga
      601 ctaactcgtc attcatctcg tcaaaaaagt ggtttgcacc ttggatcacc ttttgactgt
      661 actgcggatt atgtgctgca gcctgttttc gaagttcggc cgtttcgagt acaccgggaa
      721 ggtcatctgt accgtaaaga tccagcaccg gaatatttat ggttttcagt gaaatcgagc
      781 tgttgacgtc gctatctttc tgcgtcgcgc ccataccgat cgcgacaaag ccctggatgt
      841 cgttggtatt acgcgagagg taatagctcg acatcgtggc gccttggctg tgggcaacga
      901 tgaccaaggt ttttacaccc ttttgcttaa ggaagcgctc agccgccttc aggcgcggtg
      961 gaacctcagg gtacagcggc acctattctt cgtacttcgc atcgttgtgc aatatcggca
     1021 tctggatcga cagcgtatgc cagccatact ccgtcatcgc cacgcggatc ggctgcacga
     1081 cctgctgcca gtcggggtgg atgccggtgc catggacaac gatcatgccc ttgttggaac
     1141 cattggtagc ttcggtgtaa ataccgaaca cgccgcggcc atcaaccatg acatcgactt
     1201 cctcgccatc catgatcgaa tcggcgacct gctcgcgcca gcgttgctcc ttgccaaggt
     1261 cggaagcaaa gccaggcgca accagagcaa tacccagaat caacacgatg tatttcttgc
     1321 ccatttccgt tagctcctat cgcgtttctc agagaaaaac taacataagt gactcgcgtg
     1381 cgcactcagc aggtgcgcag gttaagctga ctggtctaga ctatcgacta accgcggatg
     1441 ctaactcgct cattcatctc aaccgcctca ccaacccccc caacaatttg gaggctaccg
     1501 gtggtggcca aatctatcgt tgctgtaatg ctggtgctgt tgctgacagg ttgcgctagt
     1561 atccctgatg gaatgaacgt ccaattcggc atcgacttca acccatcaaa ataacccttc
     1621 cgaaaaaatt tgaggacaac atgatgaacg cctttcaatc cttccgtaac gccgtccttg
     1681 aagatgatga cttacaagaa caggttatct ctatcgtaaa tacagcaact gccaatggct
     1741 caggacttgg cgacggcatt gctaccttgg ccaagaatca tggttacagc attacctcag
     1801 aagaagtcta tgctcatgct gatttcttag gacaagacgg tgacctgact gattttgagt
     1861 tagagatgat tagtggttga atggccagtg atactttggg cggcggtaaa agttaactcc
     1921 ctcattcatt ccaacctctt caccaaatcc tccgccctta aatgggtata gcgcatcagc
     1981 acacgcggat ctttacgcgc taagtgtgcg ttgtcttaag aagcgtgtga gcgtttcaca
     2041 gtcattcagc agtagccact tctactaaac gtatctatta ttgacctcac agctgaagga
     2101 gctctgggta aaaaggtgct cgacttgaac tcaactgatt acgagatttg acctgctatg
     2161 aagactctgg ccgaggcgct tgtatgccgg gctgataacg ctcccagcga cccggcattt
     2221 tcgtttattg aaaacgacga agggcagatc agccagttaa gtaatgctga gctcgcatcc
     2281 tgggcatggt gcgctgcaca ggcgctcacg gagaagactc gcgcaggcca gcggatcgtg
     2341 cttttggccc cggaaggtct tgacttcata gccggctttt atgcatgcat tctttctggc
     2401 cgggttgtgg ttcccaccta cccgccgaac agttcccgga ttacacgggc gactacaaga
     2461 ctgaatttgc tgattcgaga tgcagatcca gatgccattc tcacaacgca ggccttggcc
     2521 gcgcgcatca cagcactggt gcgcgagttt ggatggcggc acataccggt attaaccgtt
     2581 aaagagcgcc ctgatagtgc ctgtcgcgag acggcggaat cgatgcttaa caatattcag
     2641 ccaaggtctc cggcgatcat tcagtacacc tcgggctcga ccagtcaacc gaagggcgtg
     2701 gtgttgtcgc atcacaatct cgttaacaat gcacgaggaa tgcaggccca tggcgctttc
     2761 gatagtactt cagtgggctt ctcgtggctg ccgccctatc acgacatggg cctgatcagc
     2821 ggccttactc tgccagtttg tgttgggtat cactcggtgt tgtgtgctcc cagtcgcttc
     2881 ctcggcaggc cagcgtcctg gcttgaatct atcgaccgtt tcagtgccac gatcaccgga
     2941 ggccctaatt tcgctttcga cctatgcgta gacaaaataa aagatcaaga gatagagggt
     3001 atcagtctgt ccagcctcaa ggcggtattt aatggggccg aaccggtccg cagcttcacc
     3061 ttggcgcgct ttgttgcacg ctttaagtct tttggcttta acccagattc gttttcgcca
     3121 gtctatgggt tggcggagac cacccttatg gcggccggta ttcgggcagg ggagcccgca
     3181 gtggcgcgcg cctttgataa agaatcgctt tcttcaggtg ttgcgcttcc gccaaccggc
     3241 gggaacccaa cagtatcgtt ggtcagttgc ggcacgccgt tggtagaaca tgcgatcacg
     3301 atacatgatt cagagtcatc ggaaccactt ggcccaggcg tggtaggcga gatatacgta
     3361 gagggtccaa gtattgcatc gggatacttc agatcgggtg atgctgatgc gccgaccgct
     3421 ttttgtttaa gccaacgtta cccaggtgag atgcagtttc aaacaggcga cctgggtttc
     3481 attcttgatg accatttatt tattacaggt cggataaaag atttgatcat cgttcggggc
     3541 aaaaatcttt atccgcagga tatagagctt tcagccgcag atgcacatcc tgcaatagat
     3601 cactatcgcg tctgtgcatt ttcaattgat gatggcatgt gcgaacaact cgcgattgtc
     3661 tgcgagatta aaagaacaca taggcgcaat cttgaaacta ctacggtcac gcgattgata
     3721 cgaaaggcag ttactcagga gcataatgtg acccctgctg ttgtcagttt agttaagccc
     3781 ggaacgatcc cccttaccac aagcggaaaa attcgacgac acgcctgtcg agatttgttt
     3841 ttcgcaaagg ggtggaatcc gatttaccag cacgcgacaa acgaaggtga aaagaatcct
     3901 gattcggatg tgttgatctc agcaggctat caaaggggtc gatcgcagaa cctgacgcga
     3961 caaaaactaa aaggtttatc gcacgaggat cagacacagg caatcaaaga ttatcttgcg
     4021 acagttgtta gttcgcttct caatctatcg ccccaggcag tggtgcatga caggccgctg
     4081 atcgagtcgg gtgtggactc tctttctctg gtggagttag gccaccgaat ccggcgtgat
     4141 cttgattgtg ctgtgggctt gttcatcgaa aaagatctgt cgcttgatga cttggttcac
     4201 gagattcttg ttcaattgag tcatgatccg gtcagcgaag ggctcacagg cgtagacaga
     4261 ggcaacgcta gcaaccggga tattcccatg agtccgatac accttgagtt gctggactcg
     4321 ggtgctgacc ttgagaggca gatcgtcacc gtatacatcc ggttaccacc acaggcggac
     4381 cagaatgtcg ttaagcgaat tctgtctcac gtactcgccc agcacggcgt cttttatctt
     4441 cgcaagaact ccgagagaca acactggcga tttgttccgt cagaaaccac gagcctcttt
     4501 tcttttgccg tgctaaaagc aatcgatttg gaagaggagc aagtaaaaag gttttctaag
     4561 gagttggact ccctcgtatg tgagccattt gacttaatac aaggcccgtt ggtccatgca
     4621 gtgtttgtcg ataaagggcc aggtgagagt gggatgctgg tactgtcttt ttcccacacc
     4681 gtcgttgatg ccatatcgct atggatactt tctaacgaac tagagcaggt ctggactcag
     4741 cgaagcgata cggcagagat tcactcccca gttctggatc aatcaggtct cgattggaac
     4801 tgctaccttc acgcccacgc ccaaagtcgt gtggcaggcc agcagacgca ctattggatg
     4861 gatatcaaga aaaagatcaa tggctcactt gttgatttac agccccgtgg caatcgcgaa
     4921 gaaagttcgt tgcgggcgat atctagacct caccaacatc ctgggcggtt gaacccgttt
     4981 ctcagtttgg ccttgtctga tcgctttgca tcgttgagag agcagcatga tgtattcctt
     5041 acggcatttt tacgggcctg gtatcaggcg tctggcaatg cactctgtgc ggttagcttg
     5101 gagtcgcacg ggcggcaaca aatgggtcag tggggcataa gtggtatgcc ggttgggtgg
     5161 ttcactatgc atttccctgt tgtgtttgaa ttggatccaa gtgattccat ttggtcatcc
     5221 tgtgacaaga ttacaactgc gattaataac gtccctgaag gtggatcggg ttttgggctc
     5281 ttacggtatc tgtgttgcga cccagaaatt caaaccctgt tctcgaagtt tccggctccg
     5341 ctgatacgtt ttgtgtaccg gggaaaaatg gatcaacgct ttcgtgaccg cgatgcgttc
     5401 aagattctcg acgccagcgt tcagcgtcct tataaggcgg gccccagctc ttctgactca
     5461 aatgagatac tggtttttgt gcgccacgaa gtaggtgggt tttcatggaa tatcgagtca
     5521 acaccgggta cccgtaccga ctggaaaatg cctcctgaag aacaactggt tagcctcatg
     5581 gagcaagctc tgaatgacgg cctcaggcct ttcgataaga tgtcggcaaa agtcgctgaa
     5641 ccacggtaaa tagcaggctg gccttaatcg agtcaaaaat gtgttaaaaa gatcggttca
     5701 tattggctaa aaccagttgg gagagagttg tgagagccgt actatatttc ttgggatgtc
     5761 tcagcgatct tgatatcaaa tggctggtat ccagcggcag ggcattatcc tttgatgaag
     5821 gagagacgct ggtcgttgct ggtactcctc ttaccgacgt tttttttctg atggaaggag
     5881 agctctcagt ccgggtgggc acaagcggcg accaggaagt gaaccgcatg aaatatggag
     5941 agttctttgg agagatctct ttcctggata gccggcctcc cagtgctact attgttgcgg
     6001 tcacgccggt acgtgtgctc gcgatggatc gcgacgatat cgagggcaag ttagaccgcg
     6061 acgcggaatt tggtgcgcgc ttttttcgcg gtattggggt gttactcgca aaccggatac
     6121 gcggtctgat tcagcatgta gatgaatcaa aagaattaga cctttatgcc gatgaagtgg
     6181 caggagaact tgatcctgat cttctcgata caattaatct tgccggtcga cgttttgatt
     6241 taatgctgga tttattccga gattcattat cccgaggcta gattggcttg gaaacttgag
     6301 cgcggtgaaa tgagcgaaga gaaaaataaa gccagtccaa agcccagaag tatttttcgg
     6361 gccgaagcgc tcgaccaact tagttctccc gagcaacttg aacagctttt gcaggtgacc
     6421 ggccgcaagt cctggatcac actcgggacg attggtgtat tactcggtgc tgttctggtt
     6481 tggagtatct ttggtcggat tcctgttacg gtaagcggca ctgggattct catctatcca
     6541 aggcatgtga tgccttttca ggcttcaacg gcgggtcaat tggcttcatt aaattttgct
     6601 gttggtgacc gggttcaggc cgggcaggtc attgctacga taagtgttcc ggagatcgcc
     6661 caacgtttgg agcaggaaat cacacgactc gagcgcatga aagcgcgaca ctccacgatc
     6721 acggacctcc aaaaccaacg tttaagcctc gagacagaag cgttgcatcg caagcgcgca
     6781 atgcttaagg accgaatcga cacggccaag gcgatggccc aggcgctgcg aacgaaaaac
     6841 gaaacctaca tggcgaagca gcatacggta ctcaatgact acctgaaagc acaaactgag
     6901 ctagaggaaa cactgggtaa gcgataccaa agctttaaac ggttgcttga gtcgcagctt
     6961 acctcagacg agatggtcct tcaggcctat cagaaattag ttgatgtgcg aattaagaaa
     7021 tcagatcttg agctggaggc gcaacagctt gagctaaaga aactcgagac agaggaggcc
     7081 tacgcggaac agaaaaatcg gatagcagag tttactgcac agctgcaaga aatatctatt
     7141 gatgagacca ggctgaagca aaagggattt gaagaagccg cagaattgga tattcaaatc
     7201 caggatgcgc ttaggaatat agctcgactt gagaaatcat tgaagaaagg a
//
