LOCUS       c00454_3300025..        4686 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300025797.a:Ga0210062_1003112.
ACCESSION   c00454_3300025..
VERSION     c00454_3300025..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 13:23:28
            Original ID  :: 3300025797.a:Ga0210062_1003112
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4686
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..3015
                     /NRPS_PKS="Domain: Condensation_LCL (9-233). E-value:
                     1e-79. Score: 259.4. Matches aSDomain:
                     nrpspksdomains_ctg454_1_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (398-809). E-value:
                     9.8e-104. Score: 338.9. Matches aSDomain:
                     nrpspksdomains_ctg454_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (914-981). E-value: 1.7e-24. Score:
                     77.6. Matches aSDomain: nrpspksdomains_ctg454_1_PCP.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     374.8; E-value: 9e-114)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg454_1"
                     /sec_met_domain="Condensation (E-value: 5.8e-55, bitscore:
                     173.5, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 5.5e-116, bitscore:
                     374.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.5e-18, bitscore:
                     53.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPVIDLSALPEPVRGAESRRLVADDVHRPFDLAEPPLLRTTLLRL
                     APGVAPGSGGAEPEHLLMLSVHHIVFDGWSLGILTTELGELYDALGAGRPPGLPSLEVQ
                     YADFAYWQRTWLAGEILDEQLRYWRSRLEGAPPLLALPTDRARPAVQSYRAGSETFTLP
                     SALADRLRRLASGEGSTLFMVLLAVFELLLYRYTGQSDFNVGTFVANRRWQEIEKLVGF
                     FVNTLVLRGDLSGAPSFRELLGRVRETTLEAFEHQELPFERLLEEVDTHRDLSRTPLFQ
                     VMFGLQNFAVPTACAGALKIESVDLFEEGRANADLALWMWEEDGGLSGWLQYNSDLFDA
                     TTAQRVSGHLRGVLEGLASDPDLCPSDVPLLSAAEHHQVLVEQGGWRAPSPGAEVLGEF
                     LRRAADAPDAAALVCGGATLSYGALERRSRRAARRLAASGVAPERVVGICLERGIDQIV
                     ALLGILRAGGAYLPLDPEVPAERLAFVLDDAGAVALIARPELARRLEGFAGARLAPEEL
                     VGGAVSEEPATALEEPARGPAGSLAYVIYTSGSTGTPKGVQVDRRSLGTFTATTVAAYG
                     LEPRDRILQFGNLSFDASVEEIFPAFAAGATLVLRGEEMLASARRFLDDCARHRVSVVD
                     LPTAYWHELAAQVDARADLPRSLRLVIIGGEAALPERVAGWLDAVGPEPALVNTYGPTE
                     ATVVATSSRLERDGSDRAVAIGRTLDGVLAYVLDRDLRPLPVGVPGELLLGGAGLARGY
                     LGHPRATAERFVPDPFAGRSDGEGGGRLYRTGDLVRRRPDGELEFVGRIDHQVKIRGFR
                     IEPDEIAAVLCRHPGVREAVVVVGRDGLGGDRLAAYMAASPQVSAVALRERLRDELPAY
                     MVPADLVFLDVLPLTSTGKVDRDALPEPERGADEEYVPPETPSEELIAEIWCSLLGVDR
                     VGVHDDFFDLGGHSLLAPQVVARIGEELGIEPPLRLLLEAPTVARLALAVEELLLEQIE
                     GMSEDEAQRLVGQSA"
     protocluster    1..4686
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:3015](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..3015
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..4686
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..4686
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     aSDomain        28..699
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg454_1_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="1.00E-79"
                     /label="ctg454_1_Condensation_LCL.1"
                     /locus_tag="ctg454_1"
                     /protein_end="233"
                     /protein_start="9"
                     /score="259.4"
                     /tool="antismash"
                     /translation="PEPVRGAESRRLVADDVHRPFDLAEPPLLRTTLLRLAPGVAPGSG
                     GAEPEHLLMLSVHHIVFDGWSLGILTTELGELYDALGAGRPPGLPSLEVQYADFAYWQR
                     TWLAGEILDEQLRYWRSRLEGAPPLLALPTDRARPAVQSYRAGSETFTLPSALADRLRR
                     LASGEGSTLFMVLLAVFELLLYRYTGQSDFNVGTFVANRRWQEIEKLVGFFVNTLVLRG
                     DLS"
     aSModule        28..2943
                     /complete
                     /domains="nrpspksdomains_ctg454_1_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg454_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg454_1_PCP.1"
                     /locus_tags="ctg454_1"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       196..261
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_1_0001"
                     /evalue="3.30E-11"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg454_1"
                     /protein_end="87"
                     /protein_start="65"
                     /score="35.6"
                     /tool="antismash"
                     /translation="VHHIVFDGWSLGILTTELGELYD"
     CDS_motif       310..348
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_1_0002"
                     /evalue="1.60E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg454_1"
                     /protein_end="116"
                     /protein_start="103"
                     /score="17.4"
                     /tool="antismash"
                     /translation="QYADFAYWQRTWLA"
     CDS_motif       610..690
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_1_0003"
                     /evalue="8.40E-13"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg454_1"
                     /protein_end="230"
                     /protein_start="203"
                     /score="40.7"
                     /tool="antismash"
                     /translation="VGTFVANRRWQEIEKLVGFFVNTLVLRG"
     CDS_motif       739..858
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_1_0004"
                     /evalue="1.20E-21"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg454_1"
                     /protein_end="286"
                     /protein_start="246"
                     /score="69.1"
                     /tool="antismash"
                     /translation="RETTLEAFEHQELPFERLLEEVDTHRDLSRTPLFQVMFGLQ"
     aSDomain        1195..2427
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg454_1_AMP-binding.1"
                     /evalue="9.80E-104"
                     /label="ctg454_1_AMP-binding.1"
                     /locus_tag="ctg454_1"
                     /protein_end="809"
                     /protein_start="398"
                     /score="338.9"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FLRRAADAPDAAALVCGGATLSYGALERRSRRAARRLAASGVAPE
                     RVVGICLERGIDQIVALLGILRAGGAYLPLDPEVPAERLAFVLDDAGAVALIARPELAR
                     RLEGFAGARLAPEELVGGAVSEEPATALEEPARGPAGSLAYVIYTSGSTGTPKGVQVDR
                     RSLGTFTATTVAAYGLEPRDRILQFGNLSFDASVEEIFPAFAAGATLVLRGEEMLASAR
                     RFLDDCARHRVSVVDLPTAYWHELAAQVDARADLPRSLRLVIIGGEAALPERVAGWLDA
                     VGPEPALVNTYGPTEATVVATSSRLERDGSDRAVAIGRTLDGVLAYVLDRDLRPLPVGV
                     PGELLLGGAGLARGYLGHPRATAERFVPDPFAGRSDGEGGGRLYRTGDLVRRRPDGELE
                     FVGRIDHQVKIRG"
     CDS_motif       1381..1422
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_1_0005"
                     /evalue="3.90E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg454_1"
                     /protein_end="474"
                     /protein_start="460"
                     /score="16.9"
                     /tool="antismash"
                     /translation="LGILRAGGAYLPLDP"
     CDS_motif       1624..1680
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_1_0006"
                     /evalue="1.20E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg454_1"
                     /protein_end="560"
                     /protein_start="541"
                     /score="30.1"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGTPKGVQVDR"
     CDS_motif       2203..2292
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_1_0007"
                     /evalue="2.20E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg454_1"
                     /protein_end="764"
                     /protein_start="734"
                     /score="48.7"
                     /tool="antismash"
                     /translation="PVGVPGELLLGGAGLARGYLGHPRATAERFV"
     CDS_motif       2392..2454
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_1_0008"
                     /evalue="2.30E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg454_1"
                     /protein_end="818"
                     /protein_start="797"
                     /score="35.7"
                     /tool="antismash"
                     /translation="FVGRIDHQVKIRGFRIEPDEIA"
     aSDomain        2743..2943
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg454_1_PCP.1"
                     /evalue="1.70E-24"
                     /label="ctg454_1_PCP.1"
                     /locus_tag="ctg454_1"
                     /protein_end="981"
                     /protein_start="914"
                     /score="77.6"
                     /tool="antismash"
                     /translation="EELIAEIWCSLLGVDRVGVHDDFFDLGGHSLLAPQVVARIGEELG
                     IEPPLRLLLEAPTVARLALAVEE"
     CDS             3044..4660
                     /locus_tag="ctg454_2"
                     /transl_table=11
                     /translation="MDVLWRDVRIGLRQLARSRGFTLATIFALTLGIGATSAMVTVTEG
                     VLLQTLPYDEPDRIVLLTGTLDQGADQEDAPISYPDFADWRERSESFESLAAFTTEPFS
                     FNLLGEQDAERVSVEFVSAAYFPLLGVEPAVGRLFTPEEDRELLAHPVVVLSHSFWSRR
                     FGADPGVIGRTLDLSRKSYQVVGVTEEGFDGLTDDAEIFFPVMMPPGPDYIKLRRFRWL
                     SAVGRLAPGVSPRQAESEMATLTAALEAEHPEENEGIGVRLEVLKEAWFGKLRYGLFFL
                     LGGASILLVIACINVANLLLVRAVERQRTIAIRTALGADRWRLVRQLLTESALLALIGC
                     AFGLALASWATRILVVASRVDFKSFTEIAVDPFVVGVSVAVALACGLLFGLVPVWVTLK
                     SDLSKTLQQEGRSPGREAGRQRFQGAVVVAQVALTLVLLFTPVASGLPNSYFEWFDKVV
                     HFGLFVGVAGLGYWTVPSPTFAIALGVGLAGGTELFQGLLPYRSTELWDFLAGGSGSVA
                     GTWAAMRLKRALRGPSVDRDG"
ORIGIN
        1 ctgccggtga tcgacctctc cgcccttccg gagccggtgc gcggggcgga gagccggagg
       61 ttggtggccg acgacgtcca ccggccgttc gacctggcgg agccgccgct gctgcggacg
      121 acgctcctac ggctcgcacc cggtgtcgct ccaggttctg ggggggccga gcccgagcac
      181 ctgctgatgt tgagcgtcca ccacatcgtg ttcgacggct ggtcgctggg cattctcacc
      241 accgagctcg gcgagctgta cgacgccctc ggcgccggac ggccgcccgg gctgccgagc
      301 ctggaagtcc agtacgcgga cttcgcctac tggcagcgga cctggctcgc cggcgaaatc
      361 ctggacgagc agctccgcta ctggcgctcc cgcctggagg gggcgccgcc gctcctcgcc
      421 ctgcccaccg accgggcacg ccccgccgtc cagagctacc gggcgggctc ggagacgttc
      481 accctgccct ccgccctcgc cgatcgtctc cggcgactcg cctcgggcga aggctcgacg
      541 ctgttcatgg tgctgctggc ggtcttcgag ctcctgctct accgctacac cgggcagagt
      601 gatttcaacg tcggcacttt cgtcgccaac cgccggtggc aggagatcga gaagctcgtc
      661 gggttcttcg tcaacaccct cgtgctccgc ggagacctgt cgggcgcgcc gagcttccgc
      721 gagctgctgg gccgggtgcg ggagaccacc ttggaggcgt tcgagcacca ggagcttccg
      781 ttcgagcgcc tgctggagga ggtggacacc catcgggacc tgtcgcggac ccccctcttc
      841 caggtcatgt tcgggctcca gaacttcgcc gtgcccacgg cgtgcgccgg cgcgctgaag
      901 atcgagtcgg tcgacctgtt cgaggagggt cgggccaacg cggacctggc gctctggatg
      961 tgggaggagg atgggggatt gtcgggttgg ctgcagtaca acagcgacct gttcgacgcc
     1021 accaccgccc agcgtgtgag cggccacctc cgcggggtgc tcgaaggcct ggcctccgat
     1081 cccgacctct gcccgtcgga cgtgcctttg ctgtccgcgg ccgagcatca ccaggtgctg
     1141 gtggagcagg gcgggtggcg cgcgccctct ccgggtgccg aggtgctcgg ggagttcctc
     1201 cgacgcgcgg ccgatgctcc ggacgccgcg gccctggtct gcggaggcgc gacgctctcc
     1261 tacggcgccc tcgagcggcg gagccggcga gccgcgcgtc ggctcgcggc ctctggcgtg
     1321 gcgccggaga gggtggtcgg gatctgtctg gagcgcggga tcgaccagat cgtggcgctc
     1381 ctgggcatcc tccgcgcggg gggggcgtac ctgcccctcg acccggaggt gcccgcggag
     1441 cggctcgcgt tcgttctcga cgacgcgggg gccgtggcgt tgatcgcccg gcccgagctg
     1501 gcgcggcggc tcgagggctt cgccggagcc cggctcgcgc ccgaggagct cgtgggcggc
     1561 gcggtgtccg aggaacccgc cacggcgctc gaagaacctg ctagggggcc ggccggctcc
     1621 ctcgcctacg tcatctacac ctccgggtcg accggcacgc ccaagggcgt ccaggtcgac
     1681 cggcggtccc tgggtacgtt cacggcgacg acggtggcgg cgtacggcct ggagccccgg
     1741 gatcggatcc tccagttcgg caacctctcc ttcgacgcca gcgtggaaga gatcttcccg
     1801 gcgttcgcgg ccggggccac gctggtgctc cggggtgagg agatgctcgc ctctgcccgg
     1861 cgcttcctcg acgactgtgc ccgccaccgg gtgagcgtcg tcgacctgcc gaccgcctat
     1921 tggcacgagc tggcggcgca ggtggacgcc agggccgatc tgccgcgctc cctgcggctc
     1981 gtgatcatcg gcggcgaggc cgcgttgccc gagagggtgg ccggatggct cgatgcggtg
     2041 gggcccgagc ccgcgctggt caacacctac gggccgacgg aggcgacggt ggtggcgacg
     2101 tcctcccggc tcgagcgcga cgggtccgat cgggcggtgg ccatcgggcg gaccctcgac
     2161 ggggtcctcg cgtacgtcct cgaccgcgat ctccgcccgc tgcccgtggg cgttcccgga
     2221 gagctcctcc tgggcggagc cggcctggcc cgcggctacc tgggccaccc gcgggcgacg
     2281 gcggagcgct tcgtgcccga ccccttcgcc gggcgatcgg acggggaggg aggcggccgt
     2341 ctctaccgca ccggggacct ggtccgccgg cggccggacg gcgagctgga gttcgtcggc
     2401 cgcatcgacc accaggtcaa gatccgcggc ttccgcatcg agccggacga gatcgccgcg
     2461 gtcctctgtc gccatcccgg cgtgcgggag gcggtcgtcg tagtgggccg ggacggcctc
     2521 ggcggtgacc gtctggcggc ctatatggcg gcgtcgccgc aggtgtccgc cgtcgcgctt
     2581 cgagaacgcc tgcgtgacga gctgcccgcc tacatggtgc ccgccgacct ggtgtttctc
     2641 gacgtcctgc cgctgacctc caccggaaag gtcgaccgcg atgccttgcc ggagccggag
     2701 cgcggggcgg acgaagagta tgtgcccccc gagaccccct cggaggagct catcgccgag
     2761 atctggtgct cgctcctcgg cgtcgatcgc gtgggggtgc acgacgactt cttcgacctg
     2821 ggcggccatt cgctcctcgc tcctcaggtc gtggcacgga tcggagagga gctcggcatc
     2881 gagccgccgc tccgtctcct gctcgaggca ccgaccgtcg cccggctggc gcttgcggtc
     2941 gaggagctgc tgctcgaaca gatcgaaggg atgagcgagg acgaggccca gcgactcgtg
     3001 gggcagagcg cctgagggcg cacgacaacg ggaggacgac tgcatggacg tgctgtggag
     3061 agacgtgagg atcgggcttc ggcaactggc gaggagccgt ggattcaccc tggcgacgat
     3121 cttcgccctg accctgggga tcggtgcgac gagcgccatg gtcacggtga cggagggggt
     3181 gcttctccag acgcttccct atgacgagcc ggaccggatc gtcctgctga cggggaccct
     3241 cgaccagggt gccgaccagg aggatgcgcc gatctcctat cccgacttcg ccgattggcg
     3301 cgagcgctcg gagagcttcg agtccctggc ggccttcacc accgagccct tctcgttcaa
     3361 cctgctcggc gagcaggacg ccgaacgggt gagtgtggag ttcgtctcgg ctgcgtactt
     3421 cccattgctc ggcgtggagc cggcggtggg gaggctcttc accccggagg aggaccggga
     3481 gctcctggcc catccggtcg tggtgctcag tcactccttc tggtcccggc ggttcggggc
     3541 ggaccccggc gtcatcggcc ggaccctgga tctgagccgc aagtcctacc aggtggtggg
     3601 tgtgacagag gaggggttcg acgggctgac cgacgacgcc gagatcttct tccccgtgat
     3661 gatgcccccg gggccggact acatcaagct gcggcgcttt cgctggctct ccgcggtcgg
     3721 gcgtctggcg ccgggcgtca gcccccgcca ggcagagagc gagatggcca ccctcacggc
     3781 ggccctcgag gcggagcacc cggaagagaa cgaagggatc ggcgtccggc tcgaagtgct
     3841 caaggaagcc tggttcggca agctccgcta cggcttgttc tttctcctcg gaggggcgtc
     3901 gatcctgctc gtcatcgcct gcatcaacgt ggcgaacctg ctgctggtgc gcgccgtcga
     3961 acgccagcgc acgatcgcca tccgcaccgc cctgggggcc gaccggtggc gcctggtgcg
     4021 ccagctcctg accgagagcg ccctgctggc gctgatcggg tgcgccttcg gcctggcgct
     4081 ggcgtcatgg gccacgcgca tcctggtcgt cgcgagccgc gtcgatttca agagcttcac
     4141 cgagatcgcc gtcgaccctt tcgtggtcgg ggtcagtgtg gccgtggcgc tcgcttgcgg
     4201 cctcctgttc gggctcgtgc cggtctgggt gacgctcaag agcgacctca gcaagacgct
     4261 gcaacaggag gggcgctcgc ccggacgaga ggcggggcga cagcggttcc agggtgcggt
     4321 ggtggtcgcc caggtcgccc tgaccctggt cctcctgttc acccccgtcg ccagcgggct
     4381 cccgaacagc tacttcgagt ggttcgacaa ggtggtgcat ttcgggctgt tcgtgggggt
     4441 cgccggcctg ggctactgga cggtcccgtc tccgacgttt gccatcgcgc tgggcgtggg
     4501 gctggccggg ggcaccgagc tgttccaagg cctgctcccc taccgcagca cggaactgtg
     4561 ggattttctg gcggggggaa gcggctccgt cgccgggacc tgggccgcca tgcgactcaa
     4621 gcgcgcgctg cgggggccgt cagtcgaccg tgatggttga gatgtcgaac gacggctcgg
     4681 ggaagc
//
