LOCUS       c00165_3300025..       13980 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300025961.a:Ga0207712_10001843.
ACCESSION   c00165_3300025..
VERSION     c00165_3300025..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-24 11:24:09
            Original ID  :: 3300025961.a:Ga0207712_10001843
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13980
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..927
                     /locus_tag="ctg165_1"
                     /transl_table=11
                     /translation="FMDGGSIRTGDAFMQIYDTATGQKIFEWEAKNIKHPTHFNSPVVW
                     LEDRYFLFPEDEEAQNFIVVNLPPVTPEVNPVTIQFPSRRDASGQPAPAGVRQEVWIPL
                     VPLTKQQAAKLTAPYDTEIAEVRVSQPPAGELMFVIKEETEHRRVSRQQRDGSGEYHLK
                     VIHSYYYAVSIENPTQTRFASKEEWERGQKVSSHVATSATAPAAEVVKGSNPPYRQFPK
                     TGTTWGSPPMLSAGEWIAVFSYSQDRLFVDVYDQRMGDKLLSTALPSTVAPNESFKNAM
                     WIEGGYILLPLNKSLDSFALWQLPGGV"
     protocluster    1..13980
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4356:7227](+)"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C) or cds(LANC_like and (Pkinase or DUF4135)))
                     and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4357..7227
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C) or cds(LANC_like and (Pkinase or DUF4135)))
                     and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..13980
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C) or cds(LANC_like and (Pkinase or DUF4135)))
                     and not (YcaO or TIGR03882))"
                     /kind="single"
                     /product="lanthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13980
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide"
                     /region_number="1"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C) or
                     cds(LANC_like and (Pkinase or DUF4135))) and not (YcaO or
                     TIGR03882))"
                     /tool="antismash"
     CDS             927..1538
                     /locus_tag="ctg165_2"
                     /transl_table=11
                     /translation="VFNVCPNCGEYRVDKMVLPEGPYAVCPVCEYRHKFVRLPLFVVTG
                     ASGAGKTTTCLTAAASTKDFVVMESDILYTDEFKQPERYRELWLRVCKNISQAGKPVIL
                     CGSCIPSQFESRVERRYFSDIHYLAMVCEDEALALRLRSRPDWRRTSDDEYIARHVEFN
                     RWLKENASSTEPPMTLLDTTEITVDESVERMLRWAGKIYS"
     CDS             complement(1535..2272)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 106.3; E-value: 3e-32)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg165_3"
                     /transl_table=11
                     /translation="MDYDSTKIPVGYDRGRDHGPEFLELWMKVVASCSGSQHLDTILDL
                     GCGTGRFSESLAAHFDAKVVGVDPSKKMLDQARRKLRDQRVQYETGCGEAIPFPNDSVD
                     LIFMSMSFHHFDDQTLAARECRRVLRDGGTTLLRTGTRDRIPSYPYVEFFPGSHPILET
                     VLPTAVSIREVFASAGFSTVSSDIVVQTIAPDYATYAEKLAAGGDSVLAQLSPADFQAG
                     IEAIRAYGGDKPVCEPIDVFVFR"
     CDS             2448..3335
                     /locus_tag="ctg165_4"
                     /transl_table=11
                     /translation="MERKSASDYPQELLDLFHEYQHGDIDRRTFLDSAAKFAVGGLTVA
                     TIFESLRPNYAWAQQVPADDKRIKVGYETVPSPEGNGSIKGYLARPAKSGKQPAVLVIH
                     ENRGLNPYIEDVARRLALANFIAFAPDGLTSVGGYPGSDEKGAEAFRKVDGKKMTEDFV
                     AAAKWLKARSDSTHKLGAVGFCFGGGMVNQLAVRLGPDLNAGVAFYGRQAGVDDVPKIS
                     APLLLQYAGNDQRINEGIPAYEAALKANNKVYQVYMYDGKQHGFHNDTTPRYDEEAAKL
                     AWSRTLEFFKKYLR"
     CDS             complement(3306..3749)
                     /locus_tag="ctg165_5"
                     /transl_table=11
                     /translation="MKVIGLTPILNVSSLSESFAWFEKLGWQKHWEWGDPPNFGAVISG
                     DTEIFLCQNCQGARGGPMPTEAWDNQAGSVWMSWWLKSPAEVDAVYELALHLGITAPFP
                     PTDMPWSVHECHIRHPDGHTFRVGANIECEEEPSSPQVLLEEL"
     CDS             complement(3765..4070)
                     /locus_tag="ctg165_6"
                     /transl_table=11
                     /translation="LVLSRTWSTASLDEKGWLYRAIEVTTPEGTYRVTYNGRGLGHESV
                     TVNGEFAAGRVSAMWFIPEFSFSVGSIPALLKVKVWPWFAIRSLELIIDGQSLYSE"
     CDS             4168..4350
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg165_7"
                     /transl_table=11
                     /translation="MNDTSDAAELVAQWRDHEQDNPAGPLFASGEFAEADIVNASAEYW
                     TCGTACSGSITRFCC"
     CDS_motif       4168..4290
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MNDTSDAAELVAQWRDHEQDNPAGPLFASGEFAEADIVNAS"
                     /tool="antismash"
                     /aSTool="lanthipeptides"
                     /locus_tag="ctg165_7"
     CDS_motif       4291..4350
                     /score="-3.60"
                     /core_sequence="AEYWTCGTACSGSITRFCC"
                     /alternative_weights="1987.2"
                     /molecular_weight="1969.2"
                     /tool="antismash"
                     /aSTool="lanthipeptides"
                     /leader_location="[4167:4290](+)"
                     /peptide="lanthipeptide"
                     /prepeptide="core"
                     /leader_sequence="MNDTSDAAELVAQWRDHEQDNPAGPLFASGEFAEADIVNAS
                     "
                     /locus_tag="ctg165_7"
                     /predicted_class="Class II"
                     /monoisotopic_mass="1967.8"
     CDS             4357..7227
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     686.2; E-value: 1.3e-207)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg165_8"
                     /sec_met_domain="LANC_like (E-value: 3e-47, bitscore:
                     150.9, seeds: 47, tool: rule-based-clusters)"
                     /sec_met_domain="DUF4135 (E-value: 3.5e-78, bitscore:
                     253.2, seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFRHFARSLGCLISPALDELATQLSFVEGLSASERDVIADATRE
                     SLYTVLHSKVSRLLVLELNAARVTGRLSGENSEERWQQFLELSSGQSFWNELANHYPSL
                     LSRVDAIVLRRCAATLRFAERWAADRRRLEELCTVEVGELHELTFGAGDSHRGGATVVI
                     VRGEGSRVVYKPRSLAIDIALRGFITELAGDHGSAPNVRVPKVMDRGDYGWVEFVAHRF
                     AAGNEELLSFYRGIGHLLALMRLLSGSDLHAENVIAQGGNPVVVDCETLFTPKIPPPPS
                     GYGGAFDRAGELIARTVLSVGLLPGRGNGLGWRGVDPSALGMLPGQQPMQQQQGILGAG
                     SDKAHVGPILVEAPMSQNHPSPHPALAEFWPEVLRGFDELTATLQRLDAAGKLRPRLRV
                     FEDCRVRVVVRATEVYAEIGRMLWHPVSLHNPEPARQRAFGLLQKMAANVSAAPSDPAV
                     INAEIDELLEGDVPYFFTVVRDGRLHGPGHTYWLPPRHLVEAALTDWRSADFALEKQVI
                     QASLVSAYINDGWTSQGTSILRTHGRGGDLEARRRRQAAQIIQSIVTNTIHESDGSVAW
                     IAPVFTTTGWSVQPLQHDLYNGISGLTLLLGAYLHETAAGRADAIPELEKVFAAALQTL
                     HLGEAKRERLGDEGLNVRPLPPGAYLGLGSQIWTYLVLSHWRLDGGDGLQRACKLAGQI
                     AGAVAVDDIYDLFSGSAGAVVPLLMLTSKTGDETYFRIASQLGDRLHERAKHRNGHAYW
                     PHPLAPEGIGGFAHGVTGIGWALAHLARATGSARYEQLAQEAFAFEDALFDEQEQNWLD
                     LRMLEGSKTAAAWCHGAVGIGLAHLNLDPTLTCSSTREFVRRAAAATWRLGMGWNHCAC
                     HGDLGAWELLDHAIAAGEAPKELNASYLLDVILTSLEQDGPSCGMGRNAFAPGLLPGLG
                     GVAYQLLRAHPEHDLPSILTPDGEGF"
     CDS             complement(7240..8868)
                     /locus_tag="ctg165_9"
                     /transl_table=11
                     /translation="MQILKIVALVIFLQVGANQVTRQETLRGSVTPEREWWDLQHYNLK
                     VEFLPETRRLKGSNEITFKTLKAGNKMQIDLQPPLAITKITHGDSQLKFDREGNVYWVT
                     FEKELAQGVEDKIEVFYEGVPVVSKNPPWVGGITWGRDDLGNHFIVTTCQGIGASIWWP
                     NKDHGADEPDRGMQISVTVPENLVAVSNGRLKKTDHDVEAKKKTYHWEVVNPINNYGVN
                     VNIGNYINFTEKYQGKGGVLDVNYWVLPHQKEAAQKQFKEVTRMLDAFEHWFGKYPFYE
                     DGYKLVTVSYPGMEHQSSVTYGNWFRNGYLARDPCACGVGFKFDFIIVHESAHEWFGNN
                     ISMKDAADMWIHEGFANYSENLFVEYHFGKKDAEDYVIGTRRSIRNDIPIIGVYGTNRQ
                     GSGDMYPKGGNMLHTIRQIINDDARWLSILRGLNADFWHQTVTTEQIESYITKKAGTDL
                     SKVFDQYLRTTNIPLLKYSMNGKTLSFSYDRVVPGFAMPIRVTINGQEKVITPTEAKQT
                     LQFPEDIKTFEVNRNFYIQAEKSDL"
     CDS             complement(8906..10972)
                     /locus_tag="ctg165_10"
                     /transl_table=11
                     /translation="MRELILTVLAAFLCHIQVTANPLARDVTIYRDTYGVPHVFGRTDA
                     STVFGFAYAQAEDNFWRVEENFISALGRSSEVYGEKSLDEDRLNHALEIPRLAREEYAR
                     LDKQMRSLCDAFAAGFNYYLERHTEVKPRLLTKIEPWYTLAFIRYNYFQNGFAHDPILR
                     RAGLQTAAIENDLKPHTGSNGWVVGPAKSASGHALLFINPHLPFFGPGQVYEGHVHSEE
                     GWNFTGYTRFGFPLPYVGHNDNGGWVSTDNAADLTDVYLETFDDPARPLAYKYDNGYRL
                     ATEHVEEIRVKTATGIETRKFTMRKTHHGPILAAREGKMLSLRMAKFESDGWLREWYDM
                     TRAKSLNELKRAITPLNMLFGNVMYADRQGNTWYLYNGAVPKRDPRFDWTKALDGSDPA
                     TEWQGYHTIDELPQLTNPGTGWMQNCNTSPFLLTSDGNPDPKRFPKYMVQEGDNPRGAI
                     SREILSSKTKFTFDEWTRLAFDTRVMSAGKELEPLLAALKQSNQARLREVYDVLARWDR
                     RSANDSIAMTIFSLYHERRMRDEKLEVLAALNDALNLLERDFGTWKVAWGELNRLQRID
                     ESRDQDFDDSKPSLAVSGVNGNDGAVFTFYATPERGQKRRYGVAGGTYISVVEFGPRVR
                     ALSVHTFGASGDPKSKHYTDQSVLYTRGEFKPAWLTLEDIRANLEKAYHPGEE"
     CDS             complement(11108..11563)
                     /locus_tag="ctg165_11"
                     /transl_table=11
                     /translation="LDLKREVLRHMVATVAYRGGLACVDAPESFASFRATSTTRTPGEI
                     LAHIGDLLEGSLHLVKGEMVYLTSTPLPWKEEVTRFFTAVKAFDVYLASDAPLACAVEK
                     LVQGPIGDALTHVGQIVMLRRMSGNPIRSAAYFTAEIVAGEVNQETF"
     CDS             11627..12145
                     /locus_tag="ctg165_12"
                     /transl_table=11
                     /translation="MRVFLLMLLITLPVFAQRDRQHDFDWEIGTWKTHLRRLQRPLSGS
                     TNWVEYDGASVVSKVLDGRANLVELKVKGPAGRIEGLSLRLYNPESRKWSLNFANISDG
                     QLTIPSVGEFKDGRGEFYNKDTYNGRAILVRFVIIKITDDQYRFEQSFSDDEGKTWELN
                     WIAVDTRVK"
     CDS             complement(12154..12558)
                     /locus_tag="ctg165_13"
                     /transl_table=11
                     /translation="MNLSLAFFHGEQALVALALGGLIVVVAVPLVFYVWLRRTNSSERT
                     LTYTYAVSTAVFCVLMAVTTYDELSLSHLTVATIAFILTLPWNVITLVAVSVAGNADIG
                     NREIIAAMLLGAGVNAWILFLIAKKAKGWR"
     CDS             complement(12598..13980)
                     /locus_tag="ctg165_14"
                     /transl_table=11
                     /translation="PAPAPAKASDKDEKPAPPAAQKDRFRGVRIFDITDIKNPKQVAAV
                     QTCRGSHTHTLVTDPNDKDNIYIYVSGTSFVRQNEELAGCSGEEPDKDPNTALFRIDVI
                     KVPLASPQDAKIVSSPRLFMDPATGKLNALSNGGSHGKNGPEKPEASNQCHDITAYSAI
                     GLAAGACSGNGILIDIKDPANPKRLDAVNDPNYAYWHSASFSNDGKKLVFTDEWGGGLG
                     ARCRPNDPIKWGADSIFHVNDNKMKFASYYKMPAAQGDSENCVAHNGSLVPIPGRDILV
                     QAWYQGGISVVDFTDAEHPVEIGYFDRGPINPNMLILGGDWSAYWYNGHIYSSEIARGL
                     DVFELTPTKFITQNEINAAKSVQVGELNVQNQQKIEWPRTLVVAKAYLDQLERSQALPA
                     DQIASVRAAIQGVENTQTNHATQNKLKDLASSLEASAGTAKSAADSNRLHRLAEILMNP
                     AR"
ORIGIN
        1 ttcatggatg gcggctccat acgcaccggt gacgccttca tgcagatcta cgacaccgcg
       61 acaggccaaa agattttcga atgggaagca aagaacatca agcacccaac acacttcaat
      121 agccccgtcg tctggctgga agatcgttac ttcctctttc cggaagatga ggaggcgcaa
      181 aacttcattg tcgttaactt gccgccggtc acccctgaag taaacccggt gacgatacag
      241 ttcccttcac gaagagatgc ttccggccaa ccggcgcctg ccggagtacg ccaggaagtg
      301 tggataccac tcgtcccgtt gactaaacag caggcggcaa aacttaccgc gccgtacgat
      361 acggagattg ctgaagtgcg cgtgtcgcag cctccagccg gagagctcat gttcgtgatc
      421 aaagaggaaa cggagcatcg cagagtcagt cgccaacaga gagatggctc gggcgaatat
      481 cacctcaaag tcatccacag ttactactac gcggtgtcaa tcgagaatcc aacgcaaact
      541 cgatttgcaa gcaaagagga atgggagcgc ggtcaaaagg tcagcagtca tgttgcaacg
      601 agcgcgacgg ctccagcggc agaggtagtg aagggaagta atccgcctta tcgtcaattc
      661 ccaaagaccg gcacaacgtg gggatcgcct ccaatgttga gtgcgggtga gtggattgcg
      721 gttttcagtt atagccagga tcgtctgttt gttgacgtct acgatcagcg aatgggcgat
      781 aagcttttgt ccacggcttt gccgtctaca gtcgcaccta acgaatcgtt caagaatgcg
      841 atgtggatcg agggtggcta cattctgttg ccgctgaaca agtcactcga ttcttttgcg
      901 ctctggcagt tgccaggagg cgtttagtgt ttaatgtctg ccccaattgt ggtgagtatc
      961 gcgtagacaa gatggtccta ccggaagggc cgtacgctgt ctgtccggtt tgtgagtacc
     1021 ggcataaatt tgttcgttta ccgctgttcg ttgttactgg cgcgagtggc gccggcaaaa
     1081 caactacatg cctcacagcc gctgccagta ccaaagactt tgtggtaatg gaaagcgata
     1141 ttctttacac cgacgagttc aaacagcctg aaagatatcg agagctgtgg ctgcgcgtct
     1201 gcaagaacat ttcgcaggcg ggcaagcccg tgatcctctg cggttcgtgc ataccgtcgc
     1261 agtttgagtc tcgtgtcgag cggcgatact tttcagatat tcattatctt gcgatggtct
     1321 gtgaagatga agcgcttgcg ttgcgtttgc gaagccgtcc tgactggcgc cgcacttcgg
     1381 atgatgaata tattgcaagg cacgtggagt tcaatcgctg gttgaaagag aacgcgagca
     1441 gtacagagcc accgatgact ctcctggata ccaccgagat tacagttgat gaaagcgtcg
     1501 agcggatgct gcgctgggca gggaagatct actcttagcg aaacacgaag acgtcaatcg
     1561 gctcgcatac cggcttgtcg ccgccgtagg cacgaatcgc ctctatgccg gcttggaaat
     1621 cggccgggga caattgagcg aggaccgagt caccgcctgc tgcaagcttc tcggcgtaag
     1681 tcgcgtaatc cggagctatc gtttgaacga cgatgtcgga gctaacagtg ctaaatcccg
     1741 ccgacgcgaa aacctcccgt atagacaccg cggtcggaag aacagtttcc agaatagggt
     1801 gacttccggg aaagaactcg acgtaaggat atgacggaat tcgatcgcgc gtaccagtgc
     1861 gcagcagcgt ggtcccacca tcgcgaagca cccggcggca ttcgcgcgcc gcaagcgtct
     1921 gatcgtcaaa gtgatggaaa gacatcgaca tgaagatcag atcgacagag tcgttaggaa
     1981 aaggtatcgc ttccccacag ccagtctcat actgcaccct ctgatcccgc agcttcctcc
     2041 tcgcctggtc cagcatcttt ttagacggat cgacgcctac aaccttcgca tcgaaatgcg
     2101 ccgcgagaga ttcggagaac cgccctgtgc cgcagcccag atcgaggatc gtgtcgaggt
     2161 gctgacttcc cgagcatgac gccacgacct tcatccagag ctccaaaaac tccggcccat
     2221 ggtcgcgccc acgatcgtag ccgacgggta tcttagtcga gtcgtagtcc atgtttgatt
     2281 ccagtggcaa ctgtaggggc ggccctccgt ggccgcccgt tccacaatca tatgttattt
     2341 cgaacaaacg ggcggacacg gatggccagt taatttttct ttgtgccgct gaatgtgata
     2401 tcagttaatg cacccactaa acatcaatca cgtaacgagg agcgagaatg gaacgaaaat
     2461 cagctagcga ttacccgcag gagttgttgg acctctttca cgaataccag cacggtgata
     2521 tcgaccgccg cactttcctc gatagcgccg ccaagttcgc tgttggtgga ctgactgtcg
     2581 cgacgatctt cgagagtctc aggcccaact acgcgtgggc gcagcaagta ccggcagacg
     2641 acaaacgcat caaggtcggt tacgagaccg tgccgtcgcc ggaagggaac ggctcgatca
     2701 aaggatacct cgcgcgcccg gcaaaaagtg gaaagcagcc ggctgtgctc gtcatccacg
     2761 agaaccgcgg tctcaatcca tacatcgaag acgtggcgcg acgactcgcg ctcgcgaact
     2821 tcatagcctt cgctccagac ggattgacgt cagtgggcgg ctatcccggc agcgacgaga
     2881 aaggcgccga agccttccgc aaagttgacg gaaagaagat gacagaagat ttcgtcgcgg
     2941 cggcgaagtg gctcaaagca cgttccgatt caacacacaa actcggcgcg gtaggttttt
     3001 gtttcggcgg cggaatggtg aatcaactag ccgtgcgact tggaccagat ctgaacgcgg
     3061 gagtcgcctt ctacggacgc caggcgggcg ttgatgacgt accgaagatt tctgcgccgc
     3121 tcctgttgca atacgcaggc aacgaccagc gcatcaacga aggcatcccg gcgtacgaag
     3181 cagcgctcaa ggccaacaac aaggtctacc aggtttacat gtacgacgga aaacaacacg
     3241 gcttccacaa cgacacaaca ccgcgttacg acgaagaagc ggcgaaactg gcgtggtcgc
     3301 gcacactaga gttcttcaag aagtacctgc ggtgacgacg gttcttcttc gcactcgata
     3361 ttggccccta cgcgaaatgt gtggccgtcg ggatgtcgaa tgtgacactc atgaacgctc
     3421 cacggcatgt cagtcggcgg aaacggagcg gtgataccga ggtgcaacgc gagctcgtac
     3481 acggcgtcta cctcggctgg tgactttaac caccagctca tccaaacgct gcctgcctgg
     3541 ttgtcccacg cctcagtcgg cattgggcca ccgcgcgcgc cctgacagtt ctggcagaga
     3601 aagatttcag tatcaccgga aataacggcg ccgaaattgg gcggatcgcc ccattcccaa
     3661 tgcttctgcc aacccagctt ctcaaaccac gcaaaacttt cgcttaggct cgaaacgttc
     3721 aatatcggag tcagacctat aaccttcatc ttacctccgg atcattattc agagtaaagg
     3781 gactgcccgt cgattattag ctctaatgag cgaattgcaa accagggcca cactttgact
     3841 ttcaacagcg ccggaattga gcccacagaa aacgagaact ccgggataaa ccacatcgct
     3901 gacactctgc ctgccgcgaa ctcaccgttg accgtaacac tctcatgccc cagacccctg
     3961 ccattgtagg taacgcggta agtaccttca ggcgttgtta cctcgatggc gcgatagagc
     4021 cagccttttt catccagact tgcagtggac catgttctcg aaaggaccaa cgtggaaatt
     4081 ctccgatctt ctttgcgtta agtatggctt tgacagacgt gcacagcgtt tccgttgtag
     4141 cttaaaaccg aaaggaggaa caatagcatg aatgacacat cagatgctgc ggagctggtt
     4201 gcccaatggc gcgatcacga acaggataat cctgcaggtc cgctatttgc ctctggggag
     4261 ttcgcagaag cagatatcgt taacgcaagt gccgagtatt ggacatgtgg caccgcgtgt
     4321 agcggctcga ttacgcgctt ctgctgctaa attgacatga cattccgtca cttcgccagg
     4381 tcgctgggtt gcctgatctc gcccgctctg gacgaacttg caacccagct ttccttcgtt
     4441 gaaggactga gcgcgagcga gcgtgacgtc atcgccgatg caacgcggga atcgctttac
     4501 acagtcctgc acagtaaagt cagccggttg ctcgttctcg agctcaacgc cgcacgtgta
     4561 accggtcgtc taagcggcga gaactccgaa gagcgttggc agcaattcct tgagctctca
     4621 tccgggcagt ccttctggaa cgaattagct aatcattatc cctctttatt gtcgcgagta
     4681 gacgcgatcg tgctgaggcg atgcgcggca acgctacgct tcgctgagcg ttgggccgca
     4741 gaccgtcgcc ggttagaaga gctgtgcacc gttgaggtgg gcgaactgca cgagctcacc
     4801 ttcggagccg gtgacagcca tcgcggcggg gcgaccgtgg taattgtgcg cggtgagggc
     4861 tcgcgtgttg tttacaagcc gcgttcattg gcaattgaca tcgctttgcg cggcttcatc
     4921 accgagcttg ccggcgatca tggcagtgcg ccgaatgtcc gcgtccccaa ggtcatggat
     4981 cgtggcgatt acggctgggt tgaatttgtg gcccatcgct tcgcggcagg aaacgaggaa
     5041 ctgcttagct tctatcgcgg catcgggcat ttactcgcat taatgcgttt gctcagcggg
     5101 agcgatctac acgctgaaaa tgtaattgcc cagggcggaa accccgtggt agtcgactgt
     5161 gaaacccttt ttacgcccaa aatcccaccg ccgccatccg gctacggagg ggcgtttgac
     5221 cgcgccggcg aattgatagc tcgaacagta ctgagtgtag gcttgttacc gggccgcgga
     5281 aatggtctgg gttggcgcgg cgttgatcct tccgctttgg gaatgcttcc tggacagcag
     5341 cccatgcagc agcagcaagg aatcctcggc gcgggttcgg acaaagcgca tgtcggacca
     5401 atccttgttg aagcgccaat gtcgcaaaat catcccagcc ctcaccctgc gctcgctgaa
     5461 ttctggccag aggtactgcg tgggtttgat gaattaacgg ccacgctcca gcgcctggat
     5521 gctgccggca agttgcgacc gcggctgcgg gtgttcgagg attgccgcgt ccgcgtggtg
     5581 gtgcgtgcga ccgaggtcta tgccgagatc ggccggatgc tatggcatcc tgtatcgctg
     5641 cataaccctg aaccggcacg gcagcgcgcc ttcggcttat tgcagaaaat ggccgcgaac
     5701 gtctccgcgg cgccgagcga tccggcggtc atcaatgccg agatcgacga attgctggag
     5761 ggcgatgtcc cttacttttt cactgtggtg cgggacggtc gcttgcacgg gccggggcac
     5821 acatattggc ttccaccccg tcatttagtt gaagccgcgc tcacggattg gcgtagtgcg
     5881 gatttcgctc tcgagaaaca agtcatccag gcatcgttgg taagcgctta catcaacgac
     5941 ggctggacgt ctcagggaac atcgatatta cggacgcatg gacgcggcgg cgatctggaa
     6001 gcccgtcgcc gccggcaagc cgcgcaaatc attcaatcga tagtgacaaa tacgattcat
     6061 gagagcgacg gcagcgtggc ttggattgca ccggtgttta caacaacggg ctggtcagtg
     6121 cagcccttgc agcacgattt gtacaacggg atctcgggac tcacgttatt gcttggcgct
     6181 tatctgcacg aaacagcagc cgggcgcgcc gatgccattc ctgaacttga aaaagtgttt
     6241 gcagcggctt tgcaaacgtt acacctgggt gaggccaagc gtgaacgtct gggcgacgaa
     6301 gggctgaacg tcaggcccct tccacccggc gcgtatctcg gacttggttc gcaaatctgg
     6361 acctaccttg tgttgtcgca ttggcggttg gacggcggtg atggtttgca gcgcgcctgc
     6421 aaattggccg gccagattgc cggagcggtt gcagtggacg acatttacga tttgttttcc
     6481 ggaagcgcag gcgctgtggt tccattgctg atgcttacca gcaagacagg tgatgagact
     6541 tatttccgca tcgcttcgca acttggtgac cggttgcatg agcgcgcaaa acatcggaac
     6601 ggacatgctt actggcccca tcccctcgcg ccggaaggaa taggcggctt tgcacatggc
     6661 gtaaccggca tcggctgggc cctggcccac cttgcacgcg caaccggcag cgcgcgttac
     6721 gagcaactgg cacaagaggc gtttgccttc gaagatgctc tttttgacga gcaggagcag
     6781 aactggcttg accttcgcat gctcgaaggc tccaagaccg cagcagcgtg gtgtcacggc
     6841 gctgttggaa tcggcctggc acatctgaat ctggatccaa cgcttacatg tagctcgaca
     6901 cgtgaattcg tccggcgcgc tgcagcagca acctggcggc tggggatggg ttggaatcat
     6961 tgcgcgtgtc acggcgatct cggcgcatgg gaattactgg accacgcgat cgccgccgga
     7021 gaggcgccga aagagttaaa cgcctcgtac ctgctcgacg taatcctgac cagtctggag
     7081 caagatggac catcctgcgg catgggccga aatgccttcg cgcccggcct gttgcctgga
     7141 cttggaggag ttgcttacca attgctgcgg gctcatcccg aacatgattt gccttcgatc
     7201 ctgactcctg atggagaggg gttctgaaca agtcttcggt tagagatcac tcttctctgc
     7261 ttgaatgtag aagttgcgat tgacttcgaa cgttttgatg tcttcaggga attgaagcgt
     7321 ctgttttgct tcggtcggtg ttattacttt ctcctgaccg ttgatcgtta cgcggatcgg
     7381 catggcgaag cctgggacga ctcgatcgta gctgaatgag agcgtctttc cattcatgct
     7441 gtatttcaat aatggaatgt tggtcgtgcg caggtattga tcgaagactt tactcagatc
     7501 ggtgccggcc ttcttcgtga tgtacgactc gatctgttct gtggtgacgg tctgatgcca
     7561 aaaatctgca ttgaggccgc gcaggatcga gagccacctc gcgtcgtcgt tgatgatctg
     7621 gcgaatcgtg tggagcatgt ttccgccttt gggatacatg tctcctgacc cttgccggtt
     7681 ggtgccgtaa acgccgatga tcggaatgtc gtttcttatc gagcgacgag tgccgatcac
     7741 gtagtcttcc gcgtctttct tcccgaaatg atattcgacg aaaagatttt ccgagtaatt
     7801 cgcgaagcct tcgtgaatcc acatgtcggc cgcgtctttc atcgagatgt tgttgccgaa
     7861 ccactcatgc gccgactcgt gaacgatgat gaagtcgaat ttgaagccaa ctccgcacgc
     7921 gcaagggtcg cgagccagat agccgttgcg aaaccagttg ccgtaagtga ctgagctttg
     7981 atgctccatg ccgggataag aaaccgtcac cagcttgtaa ccgtcttcgt aaaaaggata
     8041 ctttccaaac cagtgttcga aggcgtcgag catgcgcgtt acttccttga attgcttttg
     8101 tgcggcttct ttctggtgcg gcaggaccca gtagttcacg tccagcacgc cacctttgcc
     8161 ctggtatttt tcagtaaagt tgatgtagtt gccgatgttt acgttgacgc cgtagttatt
     8221 gatggggttc acgacttccc agtgataggt tttcttcttc gcttcgacgt catggtccgt
     8281 ctttttcaag cgaccgtttg agacggcgac gagattctcg ggcacggtta cgctgatctg
     8341 catgccgcga tcgggttcgt cagcgccgtg atctttattg ggccaccaga tgctcgcgcc
     8401 gatcccctgg cacgtggtca cgatgaaatg atttccgaga tcgtctcggc cccaggtgat
     8461 cccgccaacc cacggcggat tcttactcac aaccggaacg ccttcgtaaa acacttcgat
     8521 cttgtcttcg actccctgcg cgagttcctt ctcaaacgtt acccagtaga cattgccttc
     8581 gcgatcgaat ttgagttgcg agtcgccgtg cgtgatcttg gtgatggcta gcggtggttg
     8641 cagatcgatt tgcattttgt tgccggcttt tagagtcttg aaggttatct cgttggagcc
     8701 tttcagacgc cgggtttcag ggaggaattc gactttcaga ttgtagtgct gtaagtccca
     8761 ccattcgcgt tccggagtta ctgatccgcg caatgtttcc tggcgcgtta cctgattggc
     8821 gccgacctgt aggaagatta cgagtgcaac gatttttaat atctgcatca agactcccat
     8881 tacttaacag aaatctaacc cgtggttact cttcgccggg atggtacgcc ttttcgaggt
     8941 tcgcgcggat gtcttcgagt gtgagccagg ctggtttgaa ctcaccgcgc gtgtagagca
     9001 cggactggtc cgtgtagtgc ttactctttg gatcgccgct ggcgccgaag gtgtggaccg
     9061 agagggcgcg gacgcgtggt ccaaactcga ctacgctgat gtaggttcca cctgcgacgc
     9121 cgtagcgccg tttttgtccg cgctcgggcg tagcgtaaaa cgtgaacacc gcgccgtcgt
     9181 taccattcac accgctcacc gcgaggctcg gcttggaatc gtcaaaatcc tggtcgcggc
     9241 tctcatcgat acgttgcagg cgattgagct cgccccacgc aactttccac gtgccgaaat
     9301 cgcgctccag taaattgaga gcgtcgttaa gcgcggcgag gacttccagc ttttcgtctc
     9361 tcatccggcg ctcgtgatac aagctgaaga tggtcatcgc gatcgagtcg ttagcgcttc
     9421 gtcgatccca acgagcgagt acgtcatata cttcgcgtaa ccgtgcctga ttagattgtt
     9481 tcagtgcagc aagcaacggt tccagctctt tgccggcgct catcacgcgc gtgtcaaacg
     9541 ccagccgcgt ccattcatcg aacgtgaatt tcgttttact cgaaagaatc tctctcgaga
     9601 tcgcgccgcg agggttgtcg ccttcctgga ccatgtattt gggaaaccgt ttcggatcag
     9661 gattgccatc actcgtcaaa aggaaaggac tggtgttgca gttttgcatc cagccggttc
     9721 cggggtttgt gagttgcggc aactcgtcga tcgtgtgata gccctgccat tcagtcgccg
     9781 gatcactgcc gtctaaagcc ttggtccagt cgaagcgtgg atcgcgtttc ggcaccgcgc
     9841 cgttgtagag ataccacgtg ttgccttgtc gatcggcata catcacgttg ccgaagagca
     9901 tattgagcgg cgttatcgca cgcttcagct cgttcagcga tttcgcgcgc gtcatgtcgt
     9961 accactcgcg cagccatccg tccgactcga actttgccat ccgcagcgaa agcatcttgc
    10021 cctcacgcgc ggcgaggatt gggccgtggt gcgttttgcg catcgtgaat ttgcgcgtct
    10081 cgatgccggt cgccgtcttg actcggatct cctcaacgtg ctcggtggca aggcggtatc
    10141 cattgtcgta cttgtaagcg agtggacgag cgggatcgtc gaacgtttcg aggtagacgt
    10201 cggttaagtc ggctgcgttg tcagtgctga cccaaccgcc gttgtcgttg tgtccgacgt
    10261 acggcagggg aaaaccgaaa cgtgtataac cggtgaagtt ccaaccttct tcgctatgaa
    10321 catggccttc gtaaacctgg cccggaccaa agaacggcag atgaggattg atgaaaagca
    10381 gcgcgtggcc ggaagcactc tttgctgggc caacgaccca gccgttcgag ccggtgtgtg
    10441 gtttgagatc gttctcgatc gcggcggttt ggagtccggc gcgtcgcagg attggatcgt
    10501 gcgcgaagcc gttctgaaag tagttgtaac ggatgaaggc gagtgtgtac cacggctcga
    10561 tcttcgtcag caggcgcggt ttcacttccg tgtgacgttc gagatagtag ttgaagccgg
    10621 cggcgaaggc gtcgcataag gagcgcatct gtttgtccag acgtgcgtat tcctcgcggg
    10681 ctaatctcgg tatctctaat gcatgattga gtcgatcttc atccagcgac ttctcgccgt
    10741 aaacttcgga cgagcggccg agggcgctga tgaagttttc ctcgacgcgc cagaagttgt
    10801 cttcagcttg agcgtaagca aagccgaaca ccgtactggc gtcggtccgg ccaaagacgt
    10861 gcgggacgcc gtaagtgtcg cgatagatcg tgacgtcgcg agcaagtggg tttgccgtta
    10921 cctgaatgtg acacaaaaaa gccgccaata ctgttaggat cagttcgcgc atggaacgga
    10981 tgatgccaca aagaggcgca aaaagtgagg tcttttcgtt cagagttcaa gctttagctt
    11041 gcgtgatcga cgtctagtaa cgttgaagtt gtttacgctg caagctaaag cttgaactct
    11101 gaacaagtca gaaggtttcc tggttgacct cgcccgcgac tatctcggcg gtgaagtacg
    11161 ctgccgagcg aatgggattt cctgacatac gccgcaacat cacgatctgg ccgacgtgcg
    11221 tgagcgcatc accgatcggg ccttgcacga gtttctcaac cgcacaggcg agcggagcgt
    11281 ccgatgccag gtacacgtcg aacgctttga cagcggtgaa gaatcgggtg acttcttcct
    11341 tccagggcag gggagtggac gttaagtaga ccatctcgcc tttaacgaga tgaagcgagc
    11401 cctcgagtag atcgccgatg tgcgcgagaa tttctccggg agtgcgtgtc gttgacgtgg
    11461 cacgaaacga ggcgaagctc tccggcgcat ccacgcaagc aagaccgccg cgatacgcta
    11521 ccgtcgcaac catgtgacgc aacacttcac gttttaagtc caatcgcgta gttacctcca
    11581 ggtaccttat tgactcaagc tttgccggga gcttaatttc aatggcatga gagtttttct
    11641 tctaatgctg ttaattacgt tgccggtctt cgcgcagaga gacaggcagc acgatttcga
    11701 ctgggagatc ggcacctgga agacccactt gcgtcgcttg cagcgtcctt taagcggctc
    11761 gacgaactgg gtcgagtatg acggcgcgtc ggtcgtgagt aaagttctgg atggtcgcgc
    11821 caatctcgtc gagttgaagg ttaagggtcc agccggccgt atagaaggac tgagcttgcg
    11881 tttatataat ccggagtcgc gcaagtggag tctcaatttc gcgaacatca gcgacggcca
    11941 actgactatt ccctcggttg gggagttcaa ggatggacgc ggcgaattct ataataagga
    12001 cacctacaac ggtcgtgcga tactggtgag atttgtgatc ataaagatca cggatgatca
    12061 ataccggttt gagcaatcat tctcggacga tgagggaaag acgtgggagc taaactggat
    12121 tgcggtcgat acgcgcgtga agtgatcgct tcatcatctc cagcccttcg ccttcttcgc
    12181 gattaaaaac aagatccatg cattgacgcc ggcgccgagc aacatcgctg ctatgatctc
    12241 gcggttacct atatctgcgt taccggccac actgaccgct acgagtgtga tgacattcca
    12301 tggcagggtg agaataaaag ctatagtagc cactgtaaga tgagacaacg acagttcgtc
    12361 atacgtggtt acagccatca aaacgcaaaa gacagccgtt gatactgcat aggtatatgt
    12421 gagtgttcgc tccgatgagt tcgtgcgccg gagccagacg tagaatacca acgggacggc
    12481 gaccacaacg atgagaccac ccagagcaag ggccacgagc gcctgctcac catgaaagaa
    12541 tgccagagac aaattcattt ggaatccatc ctcacggtga gcagggctac gtgcaactta
    12601 acgtgcggga ttcatcagga tctccgccag tctatgcagg cgatttgaat ctgccgcgct
    12661 cttcgccgtg ccggcgctcg cttccagcga cgacgcgagg tctttcagtt tattctgtgt
    12721 ggcatggttc gtttgcgtgt tttcgacacc ttgaatcgca gcccgcaccg atgcgatttg
    12781 atctgccggc aacgcttgtg agcgctccag ttgatccagg tacgccttcg ccactaccaa
    12841 cgttcgtggc cactcgatct tctgctggtt ctgcacgttc aactcaccga cttgaacgga
    12901 cttcgcagca ttgatctcgt tttgcgtaat aaacttcgtc ggcgtcagct caaaaacgtc
    12961 caaaccgcgt gcgatttcgg aactgtagat atggccgttg taccagtaag ccgaccagtc
    13021 gccgccaagg atgagcatgt ttggattgat tggtccacga tcgaagtagc cgatctcaac
    13081 cggatgctcc gcgtcggtga agtctacgac cgagatgccg ccctgatacc acgcttgcac
    13141 taagatatcg cgaccgggaa tcggaacgag cgaaccgttg tgggccacac agttttcact
    13201 gtctccctgc gctgcgggca tcttgtagta gctcgcaaat ttcatcttgt tgtcgttcac
    13261 atggaaaatc gaatccgcgc cccacttgat cgggtcgttc ggacggcagc gagcgccgag
    13321 tccaccgccc cactcatccg tgaacacgag tttctttccg tcattcgaaa acgacgccga
    13381 atgccagtat gcgtaattcg gatcgttcac tgcgtcgagg cgcttcggat tcgcgggatc
    13441 tttaatgtcg atcaggattc cgtttccaga gcacgcgccg gcagcgagac cgattgctga
    13501 gtacgccgtg atgtcgtgac actggttact agcctcgggc ttttccggcc cgttctttcc
    13561 atgcgagccc ccgttactca aagcattcag cttgccggtg gccggatcca taaacaaacg
    13621 cggactcgag acgatcttcg catcctgcgg cgacgccagc ggcaccttga tcacgtcgat
    13681 gcgaaacagc gccgtgttcg gatctttgtc gggctcttca cccgaacacc ctgccagctc
    13741 ttcgttttgg cgtacgaaag acgttcccga aacgtagatg tagatgttgt ccttatcgtt
    13801 cggatcggta acgagcgtat gagtgtgtga gccgcggcac gtttgcaccg ctgcgacttg
    13861 cttcgggttt ttaatgtcgg tgatgtcaaa gattcgcaca ccgcggaagc gatctttctg
    13921 cgctgccgga ggcgcgggtt tctcgtcttt gtcagacgcc ttcgcaggag cgggcgcagg
//
