LOCUS       c00020_3300026..        4614 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300026116.a:Ga0207674_10043776.
ACCESSION   c00020_3300026..
VERSION     c00020_3300026..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 11:00:59
            Original ID  :: 3300026116.a:Ga0207674_10043776
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4614
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4614
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[270:4614](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      271..4614
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..4614
                     /SMILES="NC(CO)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..4614
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             2..274
                     /NRPS_PKS="Domain: PCP (1-70). E-value: 6.6e-21. Score:
                     66.1. Matches aSDomain: nrpspksdomains_ctg20_1_PCP.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_1"
                     /sec_met_domain="PP-binding (E-value: 4e-20, bitscore:
                     59.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VERRLVEIWSEVLKVDSHLISTTRSFFELGGHSLKVLSLIDRIKR
                     EYKIGMSLKDIFDKKSVRSLANYLTTVGRTDNPQKNNPEIIEIVI"
     aSDomain        5..211
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg20_1_PCP.1"
                     /evalue="6.60E-21"
                     /label="ctg20_1_PCP.1"
                     /locus_tag="ctg20_1"
                     /protein_end="70"
                     /protein_start="1"
                     /score="66.1"
                     /tool="antismash"
                     /translation="ERRLVEIWSEVLKVDSHLISTTRSFFELGGHSLKVLSLIDRIKRE
                     YKIGMSLKDIFDKKSVRSLANYLTT"
     aSModule        5..211
                     /domains="nrpspksdomains_ctg20_1_PCP.1"
                     /incomplete
                     /locus_tags="ctg20_1"
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       74..103
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg20_1_0001"
                     /evalue="3.70E-04"
                     /label="PCP_mC"
                     /locus_tag="ctg20_1"
                     /protein_end="34"
                     /protein_start="24"
                     /score="13.6"
                     /tool="antismash"
                     /translation="SFFELGGHSLK"
     CDS             271..4614
                     /NRPS_PKS="Domain: Condensation_LCL (56-342). E-value:
                     1.2e-93. Score: 305.1. Matches aSDomain:
                     nrpspksdomains_ctg20_2_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (507-913). E-value:
                     1.7e-107. Score: 351.3. Matches aSDomain:
                     nrpspksdomains_ctg20_2_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1017-1083). E-value: 4e-23. Score:
                     73.2. Matches aSDomain: nrpspksdomains_ctg20_2_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (1094-1389). E-value:
                     7e-105. Score: 343.1. Matches aSDomain:
                     nrpspksdomains_ctg20_2_Epimerization.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     337.7; E-value: 1.6e-102)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_2"
                     /sec_met_domain="Condensation (E-value: 1.5e-76, bitscore:
                     244.4, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 5.2e-117, bitscore:
                     377.9, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.1e-15, bitscore:
                     45.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIDEYITRLQKDREIFLTVQDGDISIRAREGSLTKDIVEDIRAR
                     KPEILAFFQAGPYLASPAQRRMFFLYELDNSSMAYNLSQTVRLQGALDKEKLAAAFRQL
                     LARHESLRTCFEVRDGEVYQKITDELLPELEHYVASEEEAPAVLKKFIKPFDLTKGPLI
                     RAGLIGISPLIYILMLDMHHSIADGISQDILMKDLMSLYREERLSPLPLQYKDYTAELY
                     ATRRQEKLAMQKEFWIKEFSGEISILQLPTDYGRPSVKSHEGGRVHFEIGEEQTRRLVK
                     TADRGDASLFMVMMAAYGILIHKLGNPDGIVIGVPAAGRNHPGLENMIGMFVNTLPVRT
                     HPKADQHFETYLSSLRSTVLACFENQDYTYDELVGDLRVQRDPGRNPLFDVMFVFQSHE
                     EPIPDLPGLEISLFPDPLSISKFDITLIARPTGKGLTLEMEYSTRLFKPSTIERMIGYF
                     QRIIAAVTDDPKIRIGDIEILSSVEKDLILHSFNDTTKDYPRQETIVSMFRRQVEKTPD
                     VPAIVGHGGTKTYRELQQMADKIAYWLYTAEGVRTGDKVGILLEREEWLIPSIFGILQA
                     GGVYVPIDPSYPSGRILSLVENAGLKALISRTRHLSTSLDGQMGIVDLDAMAGVISALE
                     CRKWDSGVEGSDLAYVIYTSGSTGRPKGVMIEHHSVVNRLVWMQKHYPIGKDDVLIQKT
                     PIVFDVSVWELFWWSFTGASLCMLPAGAEKDPAALIDAISRHSVTTIHFVPSMLGAFFS
                     FVKQAAAGRLLSSLRQVFASGEALKTEQVNLFNKVLRRDTGARLINLYGPTEATVDVSY
                     YECGPDVEGGAVPIGKPIDNIKLYVLYEGGALCPIGVPGELVIAGAGVSKGYLNNEALT
                     AERFVHFPMTGERIYRTGDLVKWSEDGNLLFLGRIDNQIKLRGYRIEPGEIESLLTSHE
                     QVEEAVVLLLDRDGDKQLAAYYVSHAFPGQQDLRAFLAKKLPDHMVPAYFVRLNKLPVT
                     SNGKLDRKALPEPEVNTGRGYIAPRRPEESLLAAVWSEVLGRTEIGIDDNFFSMGGDSI
                     KSIQISARMRGLGYDVSVKDIFACQTIGALSPLLRSLGSRSDQSSVEGEIALTPVQRWF
                     WEGALKYKHHFNQSVALYYPAGISRDEIKIIFEKIQDHHDALRIVFRQEEGRVVQWNRG
                     TGVEVALREVDTKEGQDPDALFREMAIEMQSGIVLESGPLLQLGLMHHQEGSRLLIVVH
                     HLVIDGISWRILLEDIETLHRQIKDGRPLQLPDKTDAYRSWSRKLGEYIKSGAYLRARS
                     YWERMTERPAVRIPRDHPGGRHLWKDSCREDLIMGERETRALLAGGQNLPMNDILLTGL
                     LLAIERQYGMGHMQIDMEGHGREPMGMGEDISRTIGWFTSLYPVWFEKKGSSLEEAVKQ
                     VKETLRRVPNKGLDHLLYRYGAGEENVAPVIVPWEPSSICFNYLGQ"
     aSDomain        439..1296
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg20_2_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="1.20E-93"
                     /label="ctg20_2_Condensation_LCL.1"
                     /locus_tag="ctg20_2"
                     /protein_end="342"
                     /protein_start="56"
                     /score="305.1"
                     /tool="antismash"
                     /translation="PYLASPAQRRMFFLYELDNSSMAYNLSQTVRLQGALDKEKLAAAF
                     RQLLARHESLRTCFEVRDGEVYQKITDELLPELEHYVASEEEAPAVLKKFIKPFDLTKG
                     PLIRAGLIGISPLIYILMLDMHHSIADGISQDILMKDLMSLYREERLSPLPLQYKDYTA
                     ELYATRRQEKLAMQKEFWIKEFSGEISILQLPTDYGRPSVKSHEGGRVHFEIGEEQTRR
                     LVKTADRGDASLFMVMMAAYGILIHKLGNPDGIVIGVPAAGRNHPGLENMIGMFVNTLP
                     VRTHPK"
     aSModule        439..4437
                     /complete
                     /domains="nrpspksdomains_ctg20_2_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg20_2_AMP-binding.1"
                     /domains="nrpspksdomains_ctg20_2_PCP.1"
                     /domains="nrpspksdomains_ctg20_2_Epimerization.1"
                     /locus_tags="ctg20_2"
                     /monomer_pairings="ser -> D-ser"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       451..474
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg20_2_0001"
                     /evalue="4.10E+00"
                     /label="NRPS-E1"
                     /locus_tag="ctg20_2"
                     /protein_end="68"
                     /protein_start="60"
                     /score="1.6"
                     /tool="antismash"
                     /translation="SPAQRRMFF"
     CDS_motif       505..615
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg20_2_0002"
                     /evalue="3.10E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg20_2"
                     /protein_end="115"
                     /protein_start="78"
                     /score="48.5"
                     /tool="antismash"
                     /translation="AYNLSQTVRLQGALDKEKLAAAFRQLLARHESLRTCFE"
     CDS_motif       811..876
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg20_2_0003"
                     /evalue="3.70E-07"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg20_2"
                     /protein_end="202"
                     /protein_start="180"
                     /score="22.7"
                     /tool="antismash"
                     /translation="MHHSIADGISQDILMKDLMSLYR"
     CDS_motif       1201..1287
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg20_2_0004"
                     /evalue="2.60E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg20_2"
                     /protein_end="339"
                     /protein_start="310"
                     /score="51.9"
                     /tool="antismash"
                     /translation="IVIGVPAAGRNHPGLENMIGMFVNTLPVRT"
     CDS_motif       1336..1455
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg20_2_0005"
                     /evalue="1.80E-16"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg20_2"
                     /protein_end="395"
                     /protein_start="355"
                     /score="52.5"
                     /tool="antismash"
                     /translation="RSTVLACFENQDYTYDELVGDLRVQRDPGRNPLFDVMFVFQ"
     aSDomain        1792..3009
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg20_2_AMP-binding.1"
                     /evalue="1.70E-107"
                     /label="ctg20_2_AMP-binding.1"
                     /locus_tag="ctg20_2"
                     /protein_end="913"
                     /protein_start="507"
                     /score="351.3"
                     /specificity="consensus: ser"
                     /tool="antismash"
                     /translation="FRRQVEKTPDVPAIVGHGGTKTYRELQQMADKIAYWLYTAEGVRT
                     GDKVGILLEREEWLIPSIFGILQAGGVYVPIDPSYPSGRILSLVENAGLKALISRTRHL
                     STSLDGQMGIVDLDAMAGVISALECRKWDSGVEGSDLAYVIYTSGSTGRPKGVMIEHHS
                     VVNRLVWMQKHYPIGKDDVLIQKTPIVFDVSVWELFWWSFTGASLCMLPAGAEKDPAAL
                     IDAISRHSVTTIHFVPSMLGAFFSFVKQAAAGRLLSSLRQVFASGEALKTEQVNLFNKV
                     LRRDTGARLINLYGPTEATVDVSYYECGPDVEGGAVPIGKPIDNIKLYVLYEGGALCPI
                     GVPGELVIAGAGVSKGYLNNEALTAERFVHFPMTGERIYRTGDLVKWSEDGNLLFLGRI
                     DNQIKLRG"
     CDS_motif       1981..2022
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg20_2_0006"
                     /evalue="5.50E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg20_2"
                     /protein_end="584"
                     /protein_start="570"
                     /score="13.4"
                     /tool="antismash"
                     /translation="FGILQAGGVYVPIDP"
     CDS_motif       2215..2274
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg20_2_0007"
                     /evalue="1.20E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg20_2"
                     /protein_end="668"
                     /protein_start="648"
                     /score="36.2"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVMIEHH"
     CDS_motif       2806..2895
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg20_2_0008"
                     /evalue="6.00E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg20_2"
                     /protein_end="875"
                     /protein_start="845"
                     /score="50.5"
                     /tool="antismash"
                     /translation="PIGVPGELVIAGAGVSKGYLNNEALTAERFV"
     CDS_motif       2974..3039
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg20_2_0009"
                     /evalue="9.60E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg20_2"
                     /protein_end="923"
                     /protein_start="901"
                     /score="36.8"
                     /tool="antismash"
                     /translation="FLGRIDNQIKLRGYRIEPGEIES"
     aSDomain        3322..3519
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg20_2_PCP.1"
                     /evalue="4.00E-23"
                     /label="ctg20_2_PCP.1"
                     /locus_tag="ctg20_2"
                     /protein_end="1083"
                     /protein_start="1017"
                     /score="73.2"
                     /tool="antismash"
                     /translation="ESLLAAVWSEVLGRTEIGIDDNFFSMGGDSIKSIQISARMRGLGY
                     DVSVKDIFACQTIGALSPLLRS"
     aSDomain        3553..4437
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg20_2_Epimerization.1"
                     /evalue="7.00E-105"
                     /label="ctg20_2_Epimerization.1"
                     /locus_tag="ctg20_2"
                     /protein_end="1389"
                     /protein_start="1094"
                     /score="343.1"
                     /tool="antismash"
                     /translation="EGEIALTPVQRWFWEGALKYKHHFNQSVALYYPAGISRDEIKIIF
                     EKIQDHHDALRIVFRQEEGRVVQWNRGTGVEVALREVDTKEGQDPDALFREMAIEMQSG
                     IVLESGPLLQLGLMHHQEGSRLLIVVHHLVIDGISWRILLEDIETLHRQIKDGRPLQLP
                     DKTDAYRSWSRKLGEYIKSGAYLRARSYWERMTERPAVRIPRDHPGGRHLWKDSCREDL
                     IMGERETRALLAGGQNLPMNDILLTGLLLAIERQYGMGHMQIDMEGHGREPMGMGEDIS
                     RTIGWFTSLYPVWFE"
     CDS_motif       3568..3597
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg20_2_0010"
                     /evalue="6.20E-03"
                     /label="NRPS-E1"
                     /locus_tag="ctg20_2"
                     /protein_end="1109"
                     /protein_start="1099"
                     /score="9.8"
                     /tool="antismash"
                     /translation="LTPVQRWFWEG"
     CDS_motif       3700..3735
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg20_2_0011"
                     /evalue="1.20E-02"
                     /label="Cy2"
                     /locus_tag="ctg20_2"
                     /protein_end="1155"
                     /protein_start="1143"
                     /score="8.5"
                     /tool="antismash"
                     /translation="DHHDALRIVFRQE"
     CDS_motif       3928..3993
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg20_2_0012"
                     /evalue="1.90E-10"
                     /label="NRPS-E2"
                     /locus_tag="ctg20_2"
                     /protein_end="1241"
                     /protein_start="1219"
                     /score="32.9"
                     /tool="antismash"
                     /translation="LLIVVHHLVIDGISWRILLEDIE"
     CDS_motif       4387..4434
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg20_2_0013"
                     /evalue="1.90E-08"
                     /label="NRPS-E5"
                     /locus_tag="ctg20_2"
                     /protein_end="1388"
                     /protein_start="1372"
                     /score="26.3"
                     /tool="antismash"
                     /translation="DISRTIGWFTSLYPVWF"
     CDS_motif       4477..4536
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg20_2_0014"
                     /evalue="4.90E-07"
                     /label="NRPS-E6"
                     /locus_tag="ctg20_2"
                     /protein_end="1422"
                     /protein_start="1402"
                     /score="22.2"
                     /tool="antismash"
                     /translation="VKETLRRVPNKGLDHLLYRYG"
ORIGIN
        1 ggtggagcgg cggctggtag agatctggtc ggaggtattg aaggtggaca gccacctgat
       61 cagcactacc cgaagcttct tcgagctggg cggccactca ttgaaggtcc tgtcattgat
      121 tgacaggatc aaaagagaat ataaaatagg aatgtcttta aaagacatat ttgataaaaa
      181 aagcgtccgc agtttagcca attatctcac taccgtcggg cggaccgaca atcctcaaaa
      241 aaataatcct gaaattatag agatcgtcat atgaaaatag atgaatacat tacccgtctg
      301 caaaaagaca gggagatctt tctgacagtg caggacggtg acatcagcat acgagcaagg
      361 gaaggctctt tgacaaagga tattgtcgaa gatataaggg ccaggaagcc ggagatactt
      421 gcctttttcc aggccgggcc ttacctggct tctcccgcgc agcgtcgtat gttcttcctg
      481 tatgaactcg acaattcttc catggcgtat aatctttcgc aaaccgtgcg gttgcagggc
      541 gcgctggata aggaaaagct ggctgcagcg ttccggcagc tgctggcaag acatgaaagt
      601 ctgcgaacct gctttgaggt cagggatgga gaggtgtatc agaagataac cgatgagctg
      661 ctgccggaac tggagcatta cgtggcatct gaagaagaag cgcctgcggt gctcaaaaaa
      721 tttataaaac ccttcgacct tacaaaaggg ccgctgataa gagcaggact tatagggata
      781 tctcccctga tatatatcct gatgctggac atgcatcatt ccattgcgga cgggatatcc
      841 caggacatcc tgatgaaaga cctgatgtca ttgtaccgtg aagagcgcct gtctcctttg
      901 cccctgcaat acaaagacta tacggcagag ttgtatgcca cccggcggca ggaaaagctg
      961 gcgatgcaaa aagaattctg gataaaggaa ttttccggcg agatcagcat attgcagctg
     1021 ccaacggatt atggaaggcc ttccgtgaag agccatgaag gaggcagggt gcattttgaa
     1081 ataggtgaag aacagacccg gcgcctggta aagacagcgg atagaggaga tgcatccctg
     1141 ttcatggtga tgatggccgc ttatgggata ttgatacata agctaggcaa tccggatggc
     1201 atcgtgatag gcgtaccggc ggcgggaagg aatcatcccg gcctggagaa tatgatcggc
     1261 atgttcgtta atacgctgcc cgtgcggacc catccaaaag cggatcaaca ttttgaaaca
     1321 tatttatcct ctctaagatc gaccgtgctg gcctgctttg agaaccagga ctatacttat
     1381 gacgagcttg tcggcgacct gcgggtgcag cgtgatccag gccgcaatcc cctgttcgat
     1441 gtcatgttcg tcttccagag ccatgaagag ccgatacccg acctgcccgg tctggagata
     1501 tctctcttcc ctgatccttt gtctatatcc aagttcgata ttacgctgat cgccagaccc
     1561 acgggtaagg gcttgacgct ggaaatggaa tattccacca ggctgttcaa accgtccacg
     1621 atagaaagga tgatcgggta ttttcaaagg atcatagcag cggtgacgga cgacccgaaa
     1681 atcaggatag gagatatcga gatcctatcg tctgtagaaa aggatctcat attacattct
     1741 ttcaacgata cgacaaagga ttatcccagg caggaaacca ttgtctcgat gttccggcgg
     1801 caggtggaga aaacacccga tgttcctgcc attgtcggac atggagggac aaagacctat
     1861 cgcgagctgc agcaaatggc agacaagatc gcctattggc tgtatacggc ggagggtgtg
     1921 cgtacgggtg ataaggtagg aattttgctg gagcgtgaag aatggctgat cccctccatc
     1981 ttcggcatat tgcaggccgg aggagtatat gtgcccatcg atccgtccta tccgtccggg
     2041 cgcatcctgt ccctggtaga gaatgcaggt ctgaaggcgc tgataagcag gaccagacat
     2101 ctttctacct ccctggacgg acagatgggc attgtcgatc tggatgctat ggcaggagtc
     2161 atcagcgcgc ttgaatgcag gaaatgggac agtggcgtcg aaggaagcga tcttgcctat
     2221 gtcatatata cttcgggctc caccggtcgc cccaaagggg taatgatcga acatcattcc
     2281 gtggtaaacc gtcttgtatg gatgcaaaag cattatccca ttggaaagga cgatgtcctt
     2341 attcaaaaaa cgccgatcgt tttcgacgta tctgtatggg agctgttctg gtggtccttt
     2401 acgggggcgt cgctatgcat gctgccggcg ggcgcggaga aagatcccgc tgccctcatc
     2461 gatgccataa gcagacattc ggtgacgacc attcattttg tgccgtccat gctgggagct
     2521 tttttttcct ttgtgaagca ggcagccgcg ggccggctgt tgtcaagcct gcggcaggtg
     2581 tttgccagcg gagaggcgct taagaccgag caggtgaacc tgttcaataa agtactgcgc
     2641 agggatactg gcgcgcggct tatcaatttg tatggaccta cggaagccac cgtcgatgtc
     2701 tcttactacg aatgcggtcc ggatgtcgaa ggaggagcgg tgccgatagg gaagccgata
     2761 gacaatatta aactgtatgt cctttatgaa ggaggcgcct tgtgtcctat aggtgttccc
     2821 ggagaattgg tgattgcggg cgccggcgta tcaaaagggt atcttaataa cgaagcattg
     2881 acggcagaac gttttgtgca tttcccgatg acgggagaaa gaatatacag gacaggggac
     2941 cttgtcaagt ggtcggaaga cgggaacctc ctttttctgg gccggataga taaccagata
     3001 aaactgcggg gttacaggat cgagccggga gaaatagaaa gcctgctgac ctcgcatgaa
     3061 caggtggaag aagccgttgt gctgctgctg gacagggacg gcgataaaca gcttgctgcg
     3121 tactatgtat cccatgcatt tcccgggcag caggatctgc gggccttcct ggccaaaaag
     3181 ctgcccgatc acatggtgcc agcctatttt gtgcggctca ataagctccc tgtgacctcc
     3241 aatggcaagc tggaccgtaa ggcgctgccg gagccggaag taaataccgg caggggttac
     3301 attgcacccc gccggcctga agaatcttta ctggccgctg tgtggtcgga ggtattggga
     3361 aggacagaga taggtatcga tgacaacttc ttttcgatgg gcggagattc gatcaagtcg
     3421 atccagatca gcgcccgaat gcgggggctg ggatatgacg tatctgtaaa ggatattttt
     3481 gcctgccaga cgattggcgc tttatcaccc ctgttgaggt cattgggaag caggagcgat
     3541 caatcatctg tcgagggaga aatagcgctg acgcctgtgc aacggtggtt ttgggaagga
     3601 gcgctgaagt ataaacatca ttttaatcaa tctgtggccc tctattatcc tgccgggatc
     3661 agccgtgatg aaataaagat catatttgaa aagatacagg atcatcacga tgcgctgcgg
     3721 atcgttttca gacaggaaga gggaagggtt gtgcagtgga acaggggtac gggagtggaa
     3781 gtagcattac gggaagtcga tacgaaggaa ggccaggacc cggatgccct gttcagggag
     3841 atggctattg aaatgcagtc gggtattgtg ctggagagcg ggcccctgct gcaattggga
     3901 ctgatgcatc atcaggaagg cagccggctt ctgatcgtgg tccatcacct tgtgatagat
     3961 ggcatatcct ggcggatatt gctggaggat atcgaaacac tgcaccgtca gattaaagac
     4021 ggacgaccgt tgcagctgcc ggacaagacg gatgcatacc gcagctggtc ccggaagctg
     4081 ggagaatata taaagagtgg ggcgtatctg cgtgcaagat cgtattggga acgcatgaca
     4141 gagcggcctg ccgtcaggat accccgtgat catcccggag ggcgtcatct ttggaaggac
     4201 agttgccggg aggatcttat catgggagag agggaaacga gggctttgct ggcgggcggg
     4261 caaaacctgc cgatgaatga tattttgctc acggggttgt tgctggccat cgagcgccag
     4321 tacgggatgg gacatatgca gatagatatg gaggggcacg ggagagagcc gatgggaatg
     4381 ggagaggata tcagcaggac cattggatgg ttcaccagcc tgtatcccgt gtggtttgaa
     4441 aagaagggca gcagcctcga agaagctgtg aaacaggtga aagaaacatt gaggagagtg
     4501 cccaataaag gactggatca tctactctac cggtatggcg ccggagaaga gaatgttgca
     4561 ccggtgatag taccatggga gccttcctcc atttgcttca attatcttgg ccag
//
