LOCUS       c00021_3300026..        4738 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300026116.a:Ga0207674_10041819.
ACCESSION   c00021_3300026..
VERSION     c00021_3300026..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 11:00:59
            Original ID  :: 3300026116.a:Ga0207674_10041819
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4738
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1446
                     /NRPS_PKS="Domain: PCP (1-53). E-value: 6.1e-08. Score:
                     24.5. Matches aSDomain: nrpspksdomains_ctg21_1_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (69-348). E-value:
                     1.4e-42. Score: 137.5. Matches aSDomain:
                     nrpspksdomains_ctg21_1_Condensation_LCL.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     174.3; E-value: 8.2e-53)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_1"
                     /sec_met_domain="Condensation (E-value: 2.9e-39, bitscore:
                     122.5, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="DISVDKTLFELGGGVVEAARLMLSIRESMGITVWLDQVFNRCSVK
                     QLAALLVNKGAKDASLIPASAHSAYYPTSPVQEKIYNQRRSADRVRRHVVICLGDWPGK
                     VDPVRLERALRTLIKIQDVLRTGFIKIGNRLFQYVRDAADVALPELQKYDATEAAVRAM
                     EKPFDDAVPGLIRVGWVEQEQGGNIVLVAADTLVCDEDSICMLLNELRDVYEGRILPPL
                     PLRYVDYAVWQDGRTGSSEEQTAFWMKQRAWQWPELALPTITVSHPTDMRPMESMSFAP
                     DQAMERKIAELAQSARTSPFCIFLSCFYILLSGVTLEDHIIIDVEIDGRIQRKLKKVAG
                     VFRDTLPIGMVVGQDACFRSFLQSLSRFIPEAAVNQRMSYDGILAAMGKSERCQAFFTC
                     HDLTDITGLIGRGMPVERYQLGMVVSQREGSHHIELLFERQLFDSDTIRQFRGYYLDVL
                     TAVLEDPLKTIESIEFIHSLGKV"
     protocluster    1..4738
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:4736]"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..4736
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..4738
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..4738
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     aSDomain        4..159
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_1_PCP.1"
                     /evalue="6.10E-08"
                     /label="ctg21_1_PCP.1"
                     /locus_tag="ctg21_1"
                     /protein_end="53"
                     /protein_start="1"
                     /score="24.5"
                     /tool="antismash"
                     /translation="ISVDKTLFELGGGVVEAARLMLSIRESMGITVWLDQVFNRCSVKQ
                     LAALLVNK"
     aSModule        4..159
                     /domains="nrpspksdomains_ctg21_1_PCP.1"
                     /incomplete
                     /locus_tags="ctg21_1"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        208..1044
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_1_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="1.40E-42"
                     /label="ctg21_1_Condensation_LCL.1"
                     /locus_tag="ctg21_1"
                     /protein_end="348"
                     /protein_start="69"
                     /score="137.5"
                     /tool="antismash"
                     /translation="YYPTSPVQEKIYNQRRSADRVRRHVVICLGDWPGKVDPVRLERAL
                     RTLIKIQDVLRTGFIKIGNRLFQYVRDAADVALPELQKYDATEAAVRAMEKPFDDAVPG
                     LIRVGWVEQEQGGNIVLVAADTLVCDEDSICMLLNELRDVYEGRILPPLPLRYVDYAVW
                     QDGRTGSSEEQTAFWMKQRAWQWPELALPTITVSHPTDMRPMESMSFAPDQAMERKIAE
                     LAQSARTSPFCIFLSCFYILLSGVTLEDHIIIDVEIDGRIQRKLKKVAGVFRDTLPIG"
     aSModule        208..1044
                     /domains="nrpspksdomains_ctg21_1_Condensation_LCL.1"
                     /incomplete
                     /locus_tags="ctg21_1"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       307..384
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0001"
                     /evalue="9.60E-07"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg21_1"
                     /protein_end="128"
                     /protein_start="102"
                     /score="21.2"
                     /tool="antismash"
                     /translation="GKVDPVRLERALRTLIKIQDVLRTGFI"
     CDS_motif       676..702
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0002"
                     /evalue="1.00E-03"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg21_1"
                     /protein_end="234"
                     /protein_start="225"
                     /score="11.8"
                     /tool="antismash"
                     /translation="YVDYAVWQDG"
     CDS             1433..3379
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 584.4; E-value: 4.5e-177)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_2"
                     /sec_met_domain="Asn_synthase (E-value: 1.3e-67, bitscore:
                     216.6, seeds: 78, tool: rule-based-clusters)"
                     /sec_met_domain="GATase_7 (E-value: 3.8e-45, bitscore:
                     140.6, seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LEKYNKNIVMCGICGFVKFDGPATVEDHNIIRNMNVKLIHRGPDA
                     QDTLVSENLAFGFCRLSIIGLNNGMQPIFNEDESLILICNGEIFNYIELREKLKKDGHV
                     FRTGSDVEVILHLYEDHGMDFLNSLNGQFAFALYDRRNRLLFCARDHMGIVPFYYTLAR
                     DTFIFGSEIKAVLQHPLVERQVDLVGLDQVLTFPGLISPRTMFKNVKSLENGHYLCVNE
                     RGEIRDREYWDLIYPEEEVKLNGATEKYYIDALEDLFNASIKLRLRADVPSGLYLSGGL
                     DSSMITMKVSQMHPGVRKEAFSIDFAESAISETPYQVLVAGESRSILNKKTFFFKDISE
                     RLRQAIYHCECPLKETYNTASLSLSESTRSKGIKVILSGEGSDELFAGYVGYRFDKMRM
                     MNLVQNASSLAEQDIRERIWGDRGYFYETNFLDLEKIKRALYSREVNESFDDINCLNHH
                     VINRERLINRDVLSRRSYIDYKLRLVDHLVCDHGDKMALANAVEVRYPFLDKDFIQFST
                     RVPPELKLKDFTEKYVLKRMAERFVPKKIIEREKFGFVAPGSPYLLQNNIEYVNDLLSY
                     DRIKKQGYFNPDQVEKLKNIYKQKGFALNIPFESDLLITVITFGILLEEFFPRASDHSQ
                     HKINDNVFSKETN"
     aSDomain        3432..4595
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_3_AMP-binding.1"
                     /evalue="1.30E-76"
                     /label="ctg21_3_AMP-binding.1"
                     /locus_tag="ctg21_3"
                     /protein_end="388"
                     /protein_start="0"
                     /score="249.5"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="MSYAELLDQCRRTAVFLRRKQLAARTIVGIMTGDRALIIPAMAGI
                     MNAGAVVVPLDGELPDQRLEAMIRDMGLEHVISSRQDRLPAALERCGVKHYFHEDILAA
                     VTPGEAAGYVCPEQDEDESLYIYFTSGSTGTPKGIVGRNISLLQFLEWEIREFRIDEHT
                     RVSQLISPYFDAYLRDIFIALLAGGTICIPPAEEDIFSPEKLTAWIQDSRINLIHCVPS
                     VFRVINNGALAPGMFPDLKLVLLSGEKIIPSELTSWYSTMGDRIQLVNFYGATESTMIR
                     SFYRIRPGDAGLPKIPIGVPIDDTELLIARKDLKPCNTLVPGDLYIVSKYVSKGYLNAP
                     ELTAERFLPFETEKLGKVTAFRTGDKGRKLPDGSIELLGREDRQVKIRG"
     aSModule        3432..4595
                     /domains="nrpspksdomains_ctg21_3_AMP-binding.1"
                     /incomplete
                     /locus_tags="ctg21_3"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS             3432..4736
                     /NRPS_PKS="Domain: AMP-binding (0-388). E-value: 1.3e-76.
                     Score: 249.5. Matches aSDomain:
                     nrpspksdomains_ctg21_3_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 244;
                     E-value: 4.1e-74)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_3"
                     /sec_met_domain="AMP-binding (E-value: 4.5e-92, bitscore:
                     296.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYAELLDQCRRTAVFLRRKQLAARTIVGIMTGDRALIIPAMAGI
                     MNAGAVVVPLDGELPDQRLEAMIRDMGLEHVISSRQDRLPAALERCGVKHYFHEDILAA
                     VTPGEAAGYVCPEQDEDESLYIYFTSGSTGTPKGIVGRNISLLQFLEWEIREFRIDEHT
                     RVSQLISPYFDAYLRDIFIALLAGGTICIPPAEEDIFSPEKLTAWIQDSRINLIHCVPS
                     VFRVINNGALAPGMFPDLKLVLLSGEKIIPSELTSWYSTMGDRIQLVNFYGATESTMIR
                     SFYRIRPGDAGLPKIPIGVPIDDTELLIARKDLKPCNTLVPGDLYIVSKYVSKGYLNAP
                     ELTAERFLPFETEKLGKVTAFRTGDKGRKLPDGSIELLGREDRQVKIRGVRVELDEIEA
                     ILHRSGLLRQAAVVAQTDEKENVSLTAFVIAAEEAV"
     CDS_motif       3804..3851
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_3_0001"
                     /evalue="2.00E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg21_3"
                     /protein_end="140"
                     /protein_start="124"
                     /score="23.4"
                     /tool="antismash"
                     /translation="YIYFTSGSTGTPKGIVG"
     CDS_motif       4392..4472
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_3_0002"
                     /evalue="2.20E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg21_3"
                     /protein_end="347"
                     /protein_start="320"
                     /score="29.6"
                     /tool="antismash"
                     /translation="VPGDLYIVSKYVSKGYLNAPELTAERFL"
     CDS_motif       4563..4625
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_3_0003"
                     /evalue="3.30E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg21_3"
                     /protein_end="398"
                     /protein_start="377"
                     /score="32.0"
                     /tool="antismash"
                     /translation="LGREDRQVKIRGVRVELDEIEA"
ORIGIN
        1 gatatcagcg tcgacaaaac tctctttgag ctggggggcg gggttgtgga ggctgccagg
       61 ctgatgttgt ccatacggga gagcatgggt attaccgtat ggctggatca ggtgttcaat
      121 cgttgctcgg tgaagcagct ggcagccctg cttgtgaaca agggggcaaa agatgccagc
      181 ctgatacctg cgtcggcgca cagcgcttat tatcccacct ccccggtgca ggaaaagata
      241 tataaccaac ggcgatcagc ggatagggtt cgccggcatg tggttatctg tttgggcgat
      301 tggccgggta aggtggatcc ggtaaggctg gagcgtgctc tgcggacgct gataaaaata
      361 caggacgtgc tgcgaacggg ttttataaag ataggcaaca ggttgttcca gtatgtccgg
      421 gacgcggcgg atgtagcgct cccggaactt caaaaatacg atgctacaga ggcggctgtc
      481 agggcgatgg aaaagccttt cgatgatgca gtccccggcc tgatacgagt gggatgggta
      541 gagcaggagc aaggcgggaa tatagtgctg gtggcggctg atacgctggt atgcgatgaa
      601 gattccatct gcatgctgct gaatgagctg cgggacgtct atgaaggacg gatattgccc
      661 ccgctgccat tgagatatgt agattacgcc gtatggcagg atggccgtac cggaagctcc
      721 gaagagcaga ctgctttttg gatgaaacaa agagcctggc aatggcccga actggcgctg
      781 ccgaccataa cggtctctca tcctacggac atgcggccga tggaaagcat gtcttttgca
      841 cctgatcagg caatggagag aaagatcgca gagctggcgc agagcgcccg cacaagccct
      901 ttttgtatct tcttatcctg cttttacatc ctgctgtcgg gagtaacgct agaggaccat
      961 ataatcatcg atgtggagat agacgggcgt atccaacgga aactgaagaa ggtggcaggt
     1021 gtatttcggg atacgctccc catcgggatg gtagtcggac aggacgcgtg ctttcgtagt
     1081 tttttgcagt cattgagcag gtttattccc gaggcagcgg tgaatcagcg tatgtcttat
     1141 gacgggatcc tggcggcgat gggtaagagt gaacgctgtc aggccttttt cacctgccac
     1201 gatcttacgg atatcacggg cctcatcggc cggggaatgc cggtggaaag atatcagctg
     1261 ggaatggtcg tcagccaaag agaaggcagc caccatattg aattgctttt tgaaaggcag
     1321 ttatttgaca gcgatacgat caggcagttc aggggatact atctggatgt gctgaccgcc
     1381 gtcctcgaag acccactgaa gacaatagaa agcattgaat ttattcactc acttggaaaa
     1441 gtataataaa aacatcgtta tgtgcggcat ttgcggtttt gtaaaatttg acggtcctgc
     1501 caccgtagaa gatcacaaca ttatccggaa tatgaatgtg aagctgatcc acagggggcc
     1561 ggacgcccag gacacgctgg tgtcggagaa cctggcattc ggtttttgcc ggctcagcat
     1621 catcggcctc aacaatggta tgcagcctat cttcaatgaa gacgagtcgc tgatattgat
     1681 ctgtaacggg gaaatattca attatatcga gctgcgggaa aagctgaaga aagatggcca
     1741 tgtattcagg accggcagcg acgttgaagt gatcctgcat ttatatgaag accatggcat
     1801 ggacttcctg aacagtctga atggtcagtt cgcctttgcg ttgtacgaca ggaggaacag
     1861 gttgctgttc tgcgcaagag accatatggg gatcgttccc ttttattata ctcttgcaag
     1921 ggacactttc attttcgggt ccgagataaa ggccgttctt caacatccgt tggtggaacg
     1981 gcaggtagac ctggtaggtc tcgaccaggt attgacgttc ccgggtctca tcagcccccg
     2041 gacgatgttc aaaaacgtca aaagcctcga gaacggacat tatttatgtg taaatgaaag
     2101 aggggagatc agggaccggg aatattggga cctcatttat ccggaggagg aggtaaagct
     2161 aaatggtgcg accgagaaat attacatcga tgcgctggag gatctattca acgcatccat
     2221 aaagctcaga ttaagagccg acgtgccttc gggattatat ctcagcggcg gactggattc
     2281 ctcaatgatc acgatgaagg tgagccagat gcatcccgga gtaaggaagg aggccttttc
     2341 catcgacttt gccgagtcgg cgatatccga aactccgtac caggtcctgg tggcggggga
     2401 aagccgctcc atcctgaata aaaagacatt ctttttcaag gacatcagcg agaggctgcg
     2461 acaggctatc taccactgtg aatgcccatt gaaagaaacc tataatacgg cctccctatc
     2521 attgtccgag tccacacggt cgaaagggat aaaggtgata ttgtcgggcg aaggttccga
     2581 cgagctgttt gcaggttatg tgggctacag gttcgacaag atgaggatga tgaacctggt
     2641 gcagaatgcg tccagccttg cggaacaaga catcagagag cggatatggg gggaccgcgg
     2701 gtatttttat gagaccaatt tcctggatct cgaaaaaata aaaagagcgt tgtattcccg
     2761 ggaggtcaat gagtcgtttg acgacatcaa ctgtctgaat caccatgtga tcaatagaga
     2821 aaggctgatc aacagggatg tattgagccg gcggtcgtac atcgactaca agctgaggct
     2881 tgtagatcat ctcgtctgcg atcacggaga taagatggct ttagccaatg ccgtcgaagt
     2941 gcggtatcct tttttggata aagattttat acagttctct acacgggtgc cgccggaatt
     3001 gaagctaaag gatttcaccg aaaagtatgt tttaaagcgg atggcggaaa gatttgttcc
     3061 gaaaaaaatc atcgagcggg aaaaattcgg ttttgtagcg ccgggcagtc cttatctgct
     3121 gcagaataat atcgaatatg tcaacgatct gctgtcttat gaccggatca aaaagcaggg
     3181 ttatttcaac cctgatcagg tggaaaagct taagaatatc tataagcaga aaggctttgc
     3241 gctaaatata ccttttgaga gcgaccttct gatcaccgtc atcaccttcg gcattctgct
     3301 ggaagaattc ttccctcggg cttccgatca ttctcagcat aaaatcaatg acaatgtatt
     3361 ttcaaaagaa actaattgac agcctgaaaa aatatggcga aaagacagct gttgaaaaca
     3421 acggacggac gatgtcctat gcggagctgc tggaccagtg tagaaggacg gccgtttttc
     3481 tccggcgaaa gcagcttgct gccagaacca tcgtggggat catgaccggg gacagagcgc
     3541 ttatcatacc ggcgatggcg gggatcatga atgccggcgc agtggtcgtg cctctcgacg
     3601 gggaactgcc ggatcagcgg cttgaagcga tgatccggga catggggctg gaacatgtca
     3661 tatcatcccg gcaggacagg ctgcctgcag cgcttgaaag atgcggggtg aagcattatt
     3721 tccatgaaga tatcctggcg gctgtcactc ccggggaggc ggccggctat gtgtgccctg
     3781 aacaggatga ggatgaaagc ctttatatat attttacttc aggcagcacg ggaacaccta
     3841 agggcatcgt gggcagaaat ataagtttat tgcagttcct ggaatgggag ataagggagt
     3901 tcaggataga tgagcatacg cgggtgagcc agctgatcag tccctatttt gatgcttatc
     3961 tcagggatat attcattgcc ttgctggccg gtggaacgat ctgtataccg ccggcggaag
     4021 aggatatctt ttctcccgaa aaattaactg cctggataca ggacagccgt atcaatctta
     4081 tccactgtgt gccaagtgta ttccgggtga tcaataacgg cgcccttgcg cccggtatgt
     4141 tccctgatct taaattggtg ctgctgtccg gtgagaagat aattccatcc gagctgacga
     4201 gctggtatag tacgatgggc gaccgtatcc agcttgtaaa cttctatggc gccaccgaat
     4261 ctaccatgat ccggtcgttc tacaggatca gacccgggga tgcggggctg ccgaagatac
     4321 ccatcggcgt tcccatcgat gatacggagc tcctgattgc caggaaagat ctcaagccat
     4381 gcaatacgct tgtgcccgga gacctgtata tcgtgtcaaa atacgtttcg aaggggtatc
     4441 tgaatgctcc ggaattgacc gccgagcgat ttctgccttt cgagacggag aagctgggga
     4501 aggtgacggc gttcaggacc ggggataagg gccggaaact tccggatggc agtatcgagc
     4561 tgcttgggag agaggaccgg caggtgaaga tcaggggtgt cagagtagag ctggatgaga
     4621 tagaagctat tctgcaccgg agtggtctgc tgcggcaggc cgccgtggtt gcccagactg
     4681 acgaaaagga aaatgtatct ctaacggctt ttgtaatcgc agcagaagag gcggtccc
//
