LOCUS       c00308_3300026..        6168 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300026144.a:Ga0209954_1000779.
ACCESSION   c00308_3300026..
VERSION     c00308_3300026..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 13:43:48
            Original ID  :: 3300026144.a:Ga0209954_1000779
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6168
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6168
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[235:6166](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      236..6166
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..6168
                     /SMILES="NC(CO)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6168
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     aSDomain        3..152
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg308_1_PP-binding.1"
                     /evalue="1.20E-07"
                     /label="ctg308_1_PP-binding.1"
                     /locus_tag="ctg308_1"
                     /protein_end="50"
                     /protein_start="0"
                     /score="23.9"
                     /tool="antismash"
                     /translation="LGGHSLLATRLLGRLRRDGSRSGEELPAGGELPLATFFEGPTVSE
                     MAEALE"
     aSModule        3..152
                     /domains="nrpspksdomains_ctg308_1_PP-binding.1"
                     /incomplete
                     /locus_tags="ctg308_1"
                     /tool="antismash"
                     /type="unknown"
     CDS             3..239
                     /NRPS_PKS="Domain: PP-binding (0-50). E-value: 1.2e-07.
                     Score: 23.9. Matches aSDomain:
                     nrpspksdomains_ctg308_1_PP-binding.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg308_1"
                     /sec_met_domain="PP-binding (E-value: 4.9e-09, bitscore:
                     23.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LGGHSLLATRLLGRLRRDGSRSGEELPAGGELPLATFFEGPTVSE
                     MAEALEVLDWAAGTAGGDSAVDDEGVEMEEGEL"
     CDS             236..6166
                     /NRPS_PKS="Domain: Condensation_LCL (517-822). E-value:
                     1.8e-111. Score: 363.7. Matches aSDomain:
                     nrpspksdomains_ctg308_2_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (989-1434). E-value:
                     1.2e-101. Score: 332.0. Matches aSDomain:
                     nrpspksdomains_ctg308_2_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1551-1622). E-value: 3.9e-20.
                     Score: 63.6. Matches aSDomain:
                     nrpspksdomains_ctg308_2_PCP.1"
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (1651-1976). E-value:
                     1.3e-109. Score: 358.7. Matches aSDomain:
                     nrpspksdomains_ctg308_2_PKS_KS.1"
                     /NRPS_PKS="type: Hybrid PKS-NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) hyb_KS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 177.7; E-value:
                     6.6e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg308_2"
                     /sec_met_domain="Condensation (E-value: 2.4e-68, bitscore:
                     217.4, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.9e-113, bitscore:
                     365.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.8e-20, bitscore:
                     59.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 3.9e-116, bitscore:
                     375.4, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VTVTDSQHGATGLATPTGRAAEILRRGERAAAAFGHPEAELTLLA
                     DSVTSTLRLETADGARYVLRLYAPGSGAGAGERARLRSEQAWLEHLAAAGLGVPAPVTA
                     PDGEPVVVLPPGEGADEAGDAASLAALFTWVEGSFIDRDELTAGAYRAVGAFLARMHRA
                     AEDFEPPAGFDLQSWPVTDLEARLSALEALSGTAGETGSGSENWARRDLPVIRAAARHV
                     AAVAAEVAPTPATWGVIHSDFQPDNFLFTDPAAPADGDVRAIDFADCGEGYFLYDVASS
                     LLRVAHRPDFAELRDAFLAGYRSQRELPAADAAGACDPKLTSSREREGARGRKAQGEST
                     PQAYPEYVEDGDRSATQQTRAPSRSQQMSGWDRRLEDFLVARALYVLAWVAEHWGEASA
                     RRHGREIAPYLLAQVRGYAERRLGRGALEEATREAGLGGLTTVGFLAHLREAGIELYLE
                     APAAGDEKLRFRAPKGALTAELKAEIRQRKAELMDFLRQAAAPAGDSAPAVTRRPEGEA
                     RELSFAQRRMWFFDRLEPGSPAYNIPPAVRLEGPLDVPVLHACLGEITRRHEVLRSTYP
                     TVDGKPRVVVAPRLDLALPLTDLSALPAGRRQAEGRRLTRLEARRPFDLGAGPLIRAGL
                     VRLATGSARAGESHLALVTFHHIVSDGWSGGVLVRELVALYAAFRRGAASPLPELPIQY
                     ADYAAWQREWLQGGVRQRQLDWWTETLAGAPEVLPLPTDRPAPAVQGYRGDKTVFRWSA
                     ALSRRVEEIARDAGATSFMALLALFQTLLARYSRQGDVTVGTPVANRVRPELEPLIGFF
                     VNTLALRTRVEPDLGFGELLRRVRRVTLGAFDHQDLPLDHLIEALRPSRDLAHQPLFQV
                     LFVLQNQPMPELSAEGLAFRPEVPKTGTATFDLTLSMRATGDGFAGSLAYRTDLFDAAT
                     MERFLGHLERLAEAAVAEPGQPLAELPILAPAERRQIVAGWNDTAKAYKGGGETLTALL
                     ARQAAATPGAVAAVFAGDGETYEERTYADLFAAASRLAHHLRTLGVGPESRVGVMAERS
                     FELVEGLLAVLLAGGAYVPLDPGYPAERLEFMAGDADLAVLLTQEALAERLPASGADIV
                     RLDADRERWANLPAEPPAVDLAPGNAAYVIYTSGSTGRPKGAVNPHRAIVNRLLWMQDA
                     FGLDASDTGGGDRVLQKTPFSFDVSVWEFFWPLVTGCALVLAKPEGHKDPVYLARLIAE
                     TGVTTLHFVPPMLAGFLGQSGLERTCRGVRRVICSGEALPRDLVERFFQRMPAATQLHN
                     LYGPTEAAIDVTWWPCFAGDPRPTVPIGRPIANLRVHVLDRRGAPTPAGVAGELHIGGV
                     GLARGYWNRPALTAERFVPDPLATDFAEAGARLYRTGDLARHLAREYVEDGDRPATQQT
                     RADSDSQQMPGEKSGLGEVEFLGRLDHQVKVRGFRIELGEVEAALADLPEVGEAVVVAR
                     DGRLVGYVTAARGGNVGDLDPAALADALGTRLPEYMVPGALVALDELPLSPNGKVDRKA
                     LPEPRRSAPGAAAGLEAGPEAPPAAPPRGEVERELASVWRRVLKLPEDAPLGRRDNFFD
                     LGGHSLMVVEVQAAIERRLGVSLEVLELFQHPTLESLGRHVAAARAGGDAAVEAAPAVR
                     RRTTASGHAGSADVAIVAVAGRFPGAADVDVFWDRLRAGEEGVRRLTRDEMLADGAPLE
                     MVDRPEWVAARGALDGVERFDAAFFGLSPREAEILDPQHRLFLETAWEVLERAGHDPAT
                     AAGRVGVWAGSTMSSYALFNLLGDRELMKNVGLYQAMLGNDKDYLATRTAYMLDLKGPA
                     ISVQTACSTSLVAAAMARRALIDGECDIALAGGSAVSARQRAGYLFQPGHINSPDGHCR
                     AFDAAAQGTVSGSGVALVAMKRLDDALADGDRVLAVVKGAAVNNDGALKIGFTAPSVQG
                     QSQVIAEAWAEAGLAPASAGYVEAHGTATPLGDPIEVAALNRAF"
     aSDomain        1787..2701
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg308_2_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="1.80E-111"
                     /label="ctg308_2_Condensation_LCL.1"
                     /locus_tag="ctg308_2"
                     /protein_end="822"
                     /protein_start="517"
                     /score="363.7"
                     /tool="antismash"
                     /translation="RELSFAQRRMWFFDRLEPGSPAYNIPPAVRLEGPLDVPVLHACLG
                     EITRRHEVLRSTYPTVDGKPRVVVAPRLDLALPLTDLSALPAGRRQAEGRRLTRLEARR
                     PFDLGAGPLIRAGLVRLATGSARAGESHLALVTFHHIVSDGWSGGVLVRELVALYAAFR
                     RGAASPLPELPIQYADYAAWQREWLQGGVRQRQLDWWTETLAGAPEVLPLPTDRPAPAV
                     QGYRGDKTVFRWSAALSRRVEEIARDAGATSFMALLALFQTLLARYSRQGDVTVGTPVA
                     NRVRPELEPLIGFFVNTLALRTRVE"
     aSModule        1787..5101
                     /complete
                     /domains="nrpspksdomains_ctg308_2_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg308_2_AMP-binding.1"
                     /domains="nrpspksdomains_ctg308_2_PCP.1"
                     /locus_tags="ctg308_2"
                     /monomer_pairings="ser -> ser"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       1847..1963
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg308_2_0001"
                     /evalue="2.70E-16"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg308_2"
                     /protein_end="576"
                     /protein_start="537"
                     /score="51.9"
                     /tool="antismash"
                     /translation="PAYNIPPAVRLEGPLDVPVLHACLGEITRRHEVLRSTYPT"
     CDS_motif       2198..2263
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg308_2_0002"
                     /evalue="3.60E-12"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg308_2"
                     /protein_end="676"
                     /protein_start="654"
                     /score="38.6"
                     /tool="antismash"
                     /translation="FHHIVSDGWSGGVLVRELVALYA"
     CDS_motif       2312..2350
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg308_2_0003"
                     /evalue="4.70E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg308_2"
                     /protein_end="705"
                     /protein_start="692"
                     /score="19.0"
                     /tool="antismash"
                     /translation="QYADYAAWQREWLQ"
     CDS_motif       2603..2692
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg308_2_0004"
                     /evalue="5.30E-17"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg308_2"
                     /protein_end="819"
                     /protein_start="789"
                     /score="54.1"
                     /tool="antismash"
                     /translation="DVTVGTPVANRVRPELEPLIGFFVNTLALRT"
     CDS_motif       2741..2860
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg308_2_0005"
                     /evalue="4.80E-20"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg308_2"
                     /protein_end="875"
                     /protein_start="835"
                     /score="64.0"
                     /tool="antismash"
                     /translation="RRVTLGAFDHQDLPLDHLIEALRPSRDLAHQPLFQVLFVLQ"
     aSDomain        3203..4537
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg308_2_AMP-binding.1"
                     /evalue="1.20E-101"
                     /label="ctg308_2_AMP-binding.1"
                     /locus_tag="ctg308_2"
                     /protein_end="1434"
                     /protein_start="989"
                     /score="332.0"
                     /specificity="consensus: ser"
                     /tool="antismash"
                     /translation="ARQAAATPGAVAAVFAGDGETYEERTYADLFAAASRLAHHLRTLG
                     VGPESRVGVMAERSFELVEGLLAVLLAGGAYVPLDPGYPAERLEFMAGDADLAVLLTQE
                     ALAERLPASGADIVRLDADRERWANLPAEPPAVDLAPGNAAYVIYTSGSTGRPKGAVNP
                     HRAIVNRLLWMQDAFGLDASDTGGGDRVLQKTPFSFDVSVWEFFWPLVTGCALVLAKPE
                     GHKDPVYLARLIAETGVTTLHFVPPMLAGFLGQSGLERTCRGVRRVICSGEALPRDLVE
                     RFFQRMPAATQLHNLYGPTEAAIDVTWWPCFAGDPRPTVPIGRPIANLRVHVLDRRGAP
                     TPAGVAGELHIGGVGLARGYWNRPALTAERFVPDPLATDFAEAGARLYRTGDLARHLAR
                     EYVEDGDRPATQQTRADSDSQQMPGEKSGLGEVEFLGRLDHQVKVRG"
     CDS_motif       3401..3442
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg308_2_0006"
                     /evalue="9.20E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg308_2"
                     /protein_end="1069"
                     /protein_start="1055"
                     /score="15.7"
                     /tool="antismash"
                     /translation="LAVLLAGGAYVPLDP"
     CDS_motif       3635..3694
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg308_2_0007"
                     /evalue="5.00E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg308_2"
                     /protein_end="1153"
                     /protein_start="1133"
                     /score="28.2"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGAVNPHR"
     CDS_motif       4226..4315
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg308_2_0008"
                     /evalue="3.00E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg308_2"
                     /protein_end="1360"
                     /protein_start="1330"
                     /score="57.8"
                     /tool="antismash"
                     /translation="PAGVAGELHIGGVGLARGYWNRPALTAERFV"
     CDS_motif       4502..4567
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg308_2_0009"
                     /evalue="7.70E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg308_2"
                     /protein_end="1444"
                     /protein_start="1422"
                     /score="37.1"
                     /tool="antismash"
                     /translation="FLGRLDHQVKVRGFRIELGEVEA"
     aSDomain        4889..5101
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg308_2_PCP.1"
                     /evalue="3.90E-20"
                     /label="ctg308_2_PCP.1"
                     /locus_tag="ctg308_2"
                     /protein_end="1622"
                     /protein_start="1551"
                     /score="63.6"
                     /tool="antismash"
                     /translation="ERELASVWRRVLKLPEDAPLGRRDNFFDLGGHSLMVVEVQAAIER
                     RLGVSLEVLELFQHPTLESLGRHVAAA"
     aSDomain        5189..6163
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg308_2_PKS_KS.1"
                     /evalue="1.30E-109"
                     /label="ctg308_2_PKS_KS.1"
                     /locus_tag="ctg308_2"
                     /protein_end="1976"
                     /protein_start="1651"
                     /score="358.7"
                     /tool="antismash"
                     /translation="VAIVAVAGRFPGAADVDVFWDRLRAGEEGVRRLTRDEMLADGAPL
                     EMVDRPEWVAARGALDGVERFDAAFFGLSPREAEILDPQHRLFLETAWEVLERAGHDPA
                     TAAGRVGVWAGSTMSSYALFNLLGDRELMKNVGLYQAMLGNDKDYLATRTAYMLDLKGP
                     AISVQTACSTSLVAAAMARRALIDGECDIALAGGSAVSARQRAGYLFQPGHINSPDGHC
                     RAFDAAAQGTVSGSGVALVAMKRLDDALADGDRVLAVVKGAAVNNDGALKIGFTAPSVQ
                     GQSQVIAEAWAEAGLAPASAGYVEAHGTATPLGDPIEVAALNRAF"
     aSModule        5189..6163
                     /domains="nrpspksdomains_ctg308_2_PKS_KS.1"
                     /incomplete
                     /locus_tags="ctg308_2"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       5672..5719
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg308_2_0010"
                     /evalue="2.90E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="ctg308_2"
                     /protein_end="1828"
                     /protein_start="1812"
                     /score="16.3"
                     /tool="antismash"
                     /translation="GPAISVQTACSTSLVAA"
     CDS_motif       6095..6142
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg308_2_0011"
                     /evalue="9.90E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="ctg308_2"
                     /protein_end="1969"
                     /protein_start="1953"
                     /score="11.6"
                     /tool="antismash"
                     /translation="YVEAHGTATPLGDPIEV"
ORIGIN
        1 acctcggcgg ccactccctc ctcgccaccc gcctgctggg ccgcctgcgc cgcgacggct
       61 cgcgcagtgg tgaagagctg cccgccgggg gcgagctgcc cctggccacc ttcttcgagg
      121 ggccgacggt tagcgagatg gcggaggcgc tggaggtgct ggactgggcg gcgggaaccg
      181 ctggcggcga ctccgcggtg gacgacgagg gcgtggagat ggaggagggc gagctgtgac
      241 cgtcaccgac tcccagcacg gcgccaccgg cctcgccacg cccaccggcc gcgccgcgga
      301 aatcctgcgc cgaggcgagc gggcggcggc ggctttcggc cacccggagg cggagctgac
      361 cctgctcgcc gactcggtga cctccaccct ccgcctggag acggcggacg gtgcccgcta
      421 tgtcctccgc ctctacgccc ccggctccgg cgccggggct ggtgagcggg cccgcctgcg
      481 ctccgagcag gcgtggctgg agcacctggc ggcggcgggc ctcggcgtcc ccgcgccggt
      541 gacggcgccg gacggcgagc cggtggtcgt cctgccgccc ggggagggcg ccgatgaggc
      601 tggggacgcc gccagcctgg ccgccctctt cacctgggtc gagggcagct tcatcgaccg
      661 cgacgagctg accgccggtg cctaccgcgc cgtcggcgcc ttcctggcgc ggatgcaccg
      721 ggcggcggag gacttcgagc cccccgccgg cttcgacctt cagagctggc cggtcaccga
      781 cctggaggcg cggttgtctg cgctggaggc cctgagcggt acggccggag agacgggaag
      841 cggttcagag aactgggcgc gcagagacct gccggtgatc cgcgccgccg cccgccacgt
      901 cgccgccgtg gccgccgagg tggcgcccac cccggccacc tggggcgtca tccacagcga
      961 cttccagccc gacaacttcc tcttcaccga ccccgcggcg ccggctgacg gagacgtgcg
     1021 ggccatcgac ttcgccgact gcggcgaggg ctacttcctc tacgacgtcg cctcgtccct
     1081 gctccgcgtc gcccaccgcc ccgacttcgc cgagctgcgc gacgccttcc tcgccggcta
     1141 ccgctcccag cgcgaactgc ccgccgccga cgcggcggga gcctgcgatc ccaagctgac
     1201 atcgtcgcga gagcgtgaag gtgcccgtgg acgcaaggcg cagggcgagt cgaccccgca
     1261 ggcgtaccct gagtacgtcg aggacggcga ccggtctgca acgcagcaga cgcgggcacc
     1321 ttcgcgctcg cagcagatgt caggttggga tcgcaggctt gaggacttcc tggtcgcccg
     1381 ggcgctgtac gtcctggcct gggtggcgga gcactggggc gaggcgtcgg cgcggcgcca
     1441 cggccgggag atcgccccct acctgctggc ccaggtgcgg ggctacgccg agcgccggct
     1501 gggccgcggc gccctggagg aggcgacccg ggaggcgggg ttgggcggcc tgaccaccgt
     1561 cggcttcctg gcccatctgc gggaagccgg catcgagctg tatctcgaag ctcccgccgc
     1621 tggcgatgag aaactgcgct tccgcgctcc caagggcgcc ctgaccgccg agctgaaagc
     1681 cgagatccgc cagcgcaagg cggagctgat ggacttcctg cgccaggccg ccgctcccgc
     1741 cggcgactcc gccccggcgg tgacccggcg ccccgagggg gaggcccggg agctttcctt
     1801 cgcccagcgc cgcatgtggt tcttcgaccg cctggagccg ggcagcccgg cctacaacat
     1861 cccgccggcg gtgcgcctgg aagggccgct ggacgtaccc gtgctccacg cctgcctggg
     1921 cgaaatcacc cgccgccacg aggtcctgcg cagcacctac ccgacggtgg acggcaagcc
     1981 ccgggtggtg gtggcgcccc ggctggacct cgccctgccg ctgaccgacc tcagcgccct
     2041 gccggcgggc cgccgccagg ccgagggccg ccgcctgacc cggttggagg cgcgccgccc
     2101 cttcgacctc ggcgccggcc cgctgatccg cgccggcctg gtgcggctgg cgacggggag
     2161 cgcccgggcg ggcgagtccc acctggcgct ggtgaccttc caccacatcg tctccgacgg
     2221 ttggtccggc ggcgtcctgg tgcgcgagct ggtggccctc tacgccgcct tccgccgcgg
     2281 cgccgcctcg cccctgccgg agctgccgat ccagtacgcc gactacgccg cctggcaacg
     2341 cgaatggctg caaggcggcg tgcgtcaacg ccagctcgac tggtggaccg agaccctggc
     2401 cggcgcgccg gaggtgctgc ccctgcccac cgaccgcccg gcgccggcgg tccagggcta
     2461 ccgcggcgac aagaccgttt tccgctggtc ggcggccctg tcgcgccgcg tcgaggagat
     2521 cgcccgggac gccggcgcca cctccttcat ggcgctgctg gccctcttcc agacgctcct
     2581 ggcccgctac tcgcggcagg gcgacgtcac cgtcggcacg ccggtggcca accgggtgcg
     2641 gccggagctg gagcccctca tcggcttctt cgtcaacacc ctggcgctgc gcacccgggt
     2701 ggagccggac ctgggcttcg gcgagctgct gcgccgcgtg cgccgggtca ccctgggcgc
     2761 cttcgaccac caggacctgc cgctggacca cctcatcgag gcgctgcggc cgagccgcga
     2821 cctggcccac cagcccctct tccaggtgct cttcgtgctc cagaaccagc ccatgccgga
     2881 gctttccgcg gagggcctgg ccttccgccc ggaagtgccc aagaccggca ccgccacctt
     2941 cgacctgacc ctgtccatgc gcgccaccgg cgacggcttc gccggctccc tggcctaccg
     3001 caccgatctc ttcgacgccg cgaccatgga gcgcttcctg gggcacctgg agcggctggc
     3061 ggaggcggcg gtggcggagc cgggccagcc tctggccgag ctgccgatcc tggcgccggc
     3121 ggagcgccgg cagatcgtcg ccggctggaa cgacacggcg aaggcgtaca agggtggcgg
     3181 cgagacgctg accgctcttc tggcccgcca ggcggcggcg acgccgggcg cggtggccgc
     3241 cgtcttcgcc ggtgacggtg agacctacga ggagcgcacc tacgccgacc tcttcgccgc
     3301 cgccagccgc ctggcccacc acctgcgcac cctgggcgtc ggcccggaga gccgggtcgg
     3361 ggtgatggcg gagcgctcct tcgagctggt ggagggcctg ctggcggtgc tcctggccgg
     3421 cggcgcctac gtgccgctgg acccgggcta cccggcggag cggctggagt tcatggccgg
     3481 cgacgccgac ctggcggtgc tcctcaccca ggaagccctg gccgaacggc tgcccgccag
     3541 cggcgccgac atcgttcgcc tggacgccga tcgggagcgc tgggcgaacc tgccggcgga
     3601 accgccggcg gtggacctgg cgccgggcaa cgccgcctac gtcatctaca cctccggctc
     3661 caccggccgc cccaagggcg cggtgaaccc ccaccgggcc atcgtcaacc ggctgctctg
     3721 gatgcaggac gccttcggcc tggatgcgtc cgacaccggg ggcggtgacc gtgtgttgca
     3781 gaagaccccg ttcagctttg acgtctcggt gtgggagttc ttctggccgc tggtcaccgg
     3841 ctgcgccctg gtgctggcca agccggaggg gcacaaggac ccggtgtacc tggcccgcct
     3901 catcgccgag accggggtca ccaccctcca cttcgtgccc cccatgctgg ccggcttcct
     3961 cggccagtcg gggttggagc ggacctgccg cggcgtgcgg cgggtgatct gctccggcga
     4021 ggcgctgccc cgggacctgg tggagcgctt cttccagcgc atgccggcgg ccactcaact
     4081 ccacaacctc tacggcccca ccgaggccgc catcgacgtc acctggtggc cctgcttcgc
     4141 cggcgacccg cggccgacgg tgcccatcgg ccggcccatc gccaacctgc gggtgcatgt
     4201 gctcgaccgc cgcggcgcgc cgacgccggc gggggtggcg ggggagctgc acatcggcgg
     4261 cgtcggcctg gcccggggct actggaaccg cccggcgctg accgccgagc gcttcgtccc
     4321 cgacccgctg gcgaccgatt tcgccgaggc cggcgcccgc ctgtaccgca ccggcgacct
     4381 ggcgcgccac ctggctcgtg agtacgtcga ggacggcgat cggcctgcaa cgcagcagac
     4441 gcgggcagat tcggactcgc agcagatgcc tggcgagaag tccgggctag gcgaggtgga
     4501 gttcctgggg cgcctggacc accaggtcaa ggtgcgcggc ttccgcatcg agctgggcga
     4561 ggtcgaagcc gccctggccg acctgcccga ggtgggggag gcggtggtgg tggcccggga
     4621 cggccgcctg gtgggctacg tcaccgccgc ccggggcggc aacgtcggcg acctcgatcc
     4681 cgccgccctg gccgacgccc tgggcacccg cctgcccgag tacatggtgc ccggcgccct
     4741 ggtggccctg gacgagctgc ccctgtcgcc caacggcaag gtggatcgca aggcgctgcc
     4801 ggagccgcgg cggtcagccc cgggggcggc ggcggggctc gaagccgggc ccgaagcgcc
     4861 gcccgcggcg ccgccccggg gcgaggtgga gcgcgagctg gccagcgtct ggcgccgggt
     4921 gctgaagctg ccggaggacg cccccttggg tcgccgcgac aacttcttcg acctcggcgg
     4981 ccactccctg atggtggtgg aggtgcaggc cgccatcgag cgccgcctgg gggtctccct
     5041 ggaggtgctg gagctgttcc agcacccgac cctggaatcc ctcggccgcc acgtcgccgc
     5101 cgcccgggcc ggcggtgatg ctgccgtcga ggccgccccc gcggtgcgcc ggcgcaccac
     5161 cgcctccggc cacgccggca gcgccgacgt cgccatcgtc gccgtggcgg gccgcttccc
     5221 cggcgccgcc gacgtcgacg tcttctggga ccggctgcgc gccggcgagg agggggtgcg
     5281 ccgcctgacc cgggacgaga tgctggccga cggcgcgccg ctggagatgg tggaccgccc
     5341 cgagtgggtc gccgcccgcg gcgccctgga cggcgtcgag cgcttcgacg ccgccttctt
     5401 cggcctgtcg ccgcgggagg cggagatcct cgacccccag caccgcctgt tcctggagac
     5461 cgcctgggag gtgctggagc gggccggcca cgaccccgcc accgccgccg gccgggtcgg
     5521 tgtctgggcc ggctccacca tgtccagcta cgccctgttc aacctgctgg gggaccggga
     5581 gctgatgaag aacgtcggcc tgtaccaggc gatgctggga aacgacaagg actacctggc
     5641 gacccgcacc gcctacatgc tcgacctcaa ggggccggcg atcagcgtcc agaccgcgtg
     5701 ctccacctcg ctggtggccg ccgccatggc gcgccgggcg ctgatcgacg gtgagtgcga
     5761 catcgccctg gccggcggct cggcggtgtc ggcgcggcag cgcgccggct acctcttcca
     5821 gcccggccac atcaactcgc cggacggcca ctgccgcgcc ttcgacgcgg cagcccaggg
     5881 gacggtcagc ggcagcggcg tcgccctggt ggcgatgaag cggctggacg acgccctggc
     5941 cgacggcgac cgggtgctgg cggtggtcaa gggcgcggcg gtgaacaacg acggcgccct
     6001 caagatcggc ttcaccgcgc ccagcgtcca gggccagtcc caggtcatcg ccgaggcgtg
     6061 ggccgaggcc ggcctggcgc cggccagcgc cggctacgtc gaggcccacg gcaccgccac
     6121 ccccctcggg gaccccatcg aggtggcggc cctgaaccgc gccttcgc
//
