LOCUS       c00376_3300026..        5044 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300026144.a:Ga0209954_1001192.
ACCESSION   c00376_3300026..
VERSION     c00376_3300026..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 13:43:48
            Original ID  :: 3300026144.a:Ga0209954_1001192
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5044
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5044
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3384:5043](-)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(3385..5043)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..5044
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5044
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             complement(67..1302)
                     /locus_tag="ctg376_1"
                     /transl_table=11
                     /translation="VSGAVGTPGQDTAGRDTAGRDTAGRDTAPGATAEGAARVPVADLD
                     RLMEAALERRGVPAEHRRMMVDGLLRASLRGIDTHGVRLFPTYLAELDGGRARAEPELT
                     WHGAGPDGQVAAAEEGAGQASEPARPVPGRAGRRLDAGGALGVIAGTLAAREAARLAGR
                     HGVGAVAVSNSNHFGAASVYTLEMADRGCLGLSFTNSDALVAPFGGSRPFFGTNPLSMA
                     VQGDGGEMLCIDMATSQVSYSKVKKARERGDALEPGWAVTADGRDAARGDLGAGDDLAL
                     QPLGGYKGECLSLIVEVLCSLLAGTPFDHELSHLYVAPFDEPRGVAHLFVAFDLAAFTD
                     PAAFRARLARLLHLLRDQPPAQPGGHVLAPGDLEAAAEAERREAGIPLDAAELERFRAI
                     DAEAPAGERLGL"
     CDS             complement(1299..2645)
                     /NRPS_PKS="Domain: Aminotran_1_2 (96-438). E-value:
                     4.1e-28. Score: 90.2. Matches aSDomain:
                     nrpspksdomains_ctg376_2_Aminotran_1_2.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 303.3; E-value:
                     4.3e-92)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg376_2"
                     /transl_table=11
                     /translation="MAVMTSNEADVKRATAGQGRVTTVAVRHSLAHPSLGVMNFLNEVV
                     SRYPQAISFAPGRPWEDLFDVEQALGGVGRWVDHRAAEEERPRGELLADLGQYGRTNGI
                     LGDAIARHLQADEGIDVAPSSIMVTCGCQEAMAILLMGLFEPGRDVLLVSNPTYIGITG
                     LARVLEVDVEPVPCGDDGLEPERVAEAAARVRAAGKRPRAIYDIPDFNNPLGTSLPLAS
                     RLRLLELAEEEDLLVFEDNPYRMFAYDQPARPTLKALDPYGRVVYLGSFSKTLFPGLRL
                     GYMVADQAVEGAAGTTLAEALSPVKSLVTVNTPAPMQAAAGGILVDEDFSLARLVGEKI
                     PFYRRNRDRMVAALEKSFGERDLLDRVRWNVPGGGFFLTLDLPFEFGEAAVAEAASGEA
                     GVIVCPLSFFSLTPGHEHQVRLSFSYVSPEEIDLGVERLAAFVAERCAA"
     aSDomain        complement(1332..2357)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg376_2_Aminotran_1_2.1"
                     /evalue="4.10E-28"
                     /label="ctg376_2_Aminotran_1_2.1"
                     /locus_tag="ctg376_2"
                     /protein_end="438"
                     /protein_start="96"
                     /score="90.2"
                     /tool="antismash"
                     /translation="QYGRTNGILGDAIARHLQADEGIDVAPSSIMVTCGCQEAMAILLM
                     GLFEPGRDVLLVSNPTYIGITGLARVLEVDVEPVPCGDDGLEPERVAEAAARVRAAGKR
                     PRAIYDIPDFNNPLGTSLPLASRLRLLELAEEEDLLVFEDNPYRMFAYDQPARPTLKAL
                     DPYGRVVYLGSFSKTLFPGLRLGYMVADQAVEGAAGTTLAEALSPVKSLVTVNTPAPMQ
                     AAAGGILVDEDFSLARLVGEKIPFYRRNRDRMVAALEKSFGERDLLDRVRWNVPGGGFF
                     LTLDLPFEFGEAAVAEAASGEAGVIVCPLSFFSLTPGHEHQVRLSFSYVSPEEIDLGVE
                     RLA"
     CDS             complement(2679..3185)
                     /locus_tag="ctg376_3"
                     /transl_table=11
                     /translation="MTTQTASVLADLAVGLDHVAIAVPDLEKAVVFYRDNLGFEVLERR
                     ETKGAFTGMTSAVIKAGPIVLVLVQGLSEESQVSKYVAEYGAGVQHIAFEVKDLPQVME
                     RLKESGVEFDTNLIQGAGIRQSFTHRDPASGMMYELIERQEKDGHFTDESVAELFRQLE
                     ESGSY"
     CDS             complement(3385..5043)
                     /NRPS_PKS="Domain: PCP (162-227). E-value: 1.7e-24. Score:
                     77.6. Matches aSDomain: nrpspksdomains_ctg376_4_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (254-528). E-value:
                     3.6e-32. Score: 104.3. Matches aSDomain:
                     nrpspksdomains_ctg376_4_Thioesterase.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 81.9;
                     E-value: 5.6e-25)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg376_4"
                     /sec_met_domain="AMP-binding (E-value: 2.8e-15, bitscore:
                     43.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.9e-14, bitscore:
                     42.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LVRWLPGGAAGSAQALLDTAQLDTALLDTAQLDTAQLDTALLDYL
                     GRLDHQVKVRGFRIELGEIETALLAHSAVREAAVLARDTADGKSLAAYVSAESGPGPDP
                     AELGRHLRASLPDYMVPSAWVVLDELPLTPNGKIDRRALAAIEPQRAAGGYTPPSTPLE
                     ETLAALFAEVLGVERVGVDDDFFLAGGHSLLAVRLVARLRQPVPLATLFQAPTVRLLAA
                     ELERRGDADDAGAAGDAGGCLVRLAPGASDAAPLVLVHPGGGDLLAYVPLVRELAGGRP
                     VWGLRDPALDGAAEPLARVEAMAAHYLEELGRARRDGRLPAGPLHLAGWSLGGLVAYEM
                     ARRLERQGAAPLSLSLIDAAPHSSASRGTASRRTASRDAASRDAASSNSMPEDDAGRLV
                     TLASFAQQMGAPLADVGLGGEAALRELAAATPSRALARYAEAGRESGLLSPELAAGLER
                     RWRVFRAHAEALESYRPEAYPGPVLLLDAAEALPGRPLPSAFWRPLLGDGLRVEAVPGD
                     HFSVLRDAPEKGAARVARLLDGQLRDGETGASEEP"
     aSDomain        complement(3460..4281)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg376_4_Thioesterase.1"
                     /evalue="3.60E-32"
                     /label="ctg376_4_Thioesterase.1"
                     /locus_tag="ctg376_4"
                     /protein_end="528"
                     /protein_start="254"
                     /score="104.3"
                     /tool="antismash"
                     /translation="PLVLVHPGGGDLLAYVPLVRELAGGRPVWGLRDPALDGAAEPLAR
                     VEAMAAHYLEELGRARRDGRLPAGPLHLAGWSLGGLVAYEMARRLERQGAAPLSLSLID
                     AAPHSSASRGTASRRTASRDAASRDAASSNSMPEDDAGRLVTLASFAQQMGAPLADVGL
                     GGEAALRELAAATPSRALARYAEAGRESGLLSPELAAGLERRWRVFRAHAEALESYRPE
                     AYPGPVLLLDAAEALPGRPLPSAFWRPLLGDGLRVEAVPGDHFSVLRDAPEKG"
     aSModule        3460..4557
                     /domains="nrpspksdomains_ctg376_4_PCP.1"
                     /domains="nrpspksdomains_ctg376_4_Thioesterase.1"
                     /final_module
                     /incomplete
                     /locus_tags="ctg376_4"
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       complement(4012..4083)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg376_4_0002"
                     /evalue="7.90E-14"
                     /label="NRPS-te1"
                     /locus_tag="ctg376_4"
                     /protein_end="344"
                     /protein_start="320"
                     /score="43.9"
                     /tool="antismash"
                     /translation="PAGPLHLAGWSLGGLVAYEMARRLE"
     aSDomain        complement(4363..4557)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg376_4_PCP.1"
                     /evalue="1.70E-24"
                     /label="ctg376_4_PCP.1"
                     /locus_tag="ctg376_4"
                     /protein_end="227"
                     /protein_start="162"
                     /score="77.6"
                     /tool="antismash"
                     /translation="EETLAALFAEVLGVERVGVDDDFFLAGGHSLLAVRLVARLRQPVP
                     LATLFQAPTVRLLAAELERRG"
     CDS_motif       complement(4849..4914)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg376_4_0001"
                     /evalue="6.80E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg376_4"
                     /protein_end="65"
                     /protein_start="43"
                     /score="40.4"
                     /tool="antismash"
                     /translation="YLGRLDHQVKVRGFRIELGEIET"
     misc_feature    complement(4921..4923)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(4996..4998)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 ggaggtggtc ggtgtgaagg cggtgccggc gggccgggtc cggctggcgg tcgcggggcg
       61 ggcgggttat agccccagcc gctcccccgc cggcgcttcg gcgtcgatgg cgcggaagcg
      121 ctccagctcg gcggcgtcca gcgggatgcc ggcctcgcgg cgctccgcct cggcggcggc
      181 ctccaggtcg ccgggggcga ggacgtggcc gccgggctgc gccggcggct ggtcgcgcag
      241 caggtggagc aggcgggcca gccgggcgcg gaaggccgcc gggtcggtga aggccgcaag
      301 gtcgaaggcg acgaagagat gggccacccc ccgcggctcg tcgaacggtg cgacgtagag
      361 gtgggacagc tcgtggtcga agggcgtgcc ggcgagcagc gagcagagaa cctcgacgat
      421 gagcgacagg cactccccct tgtaaccgcc cagcggttgc agggccagat cgtcgcccgc
      481 cccgaggtcg ccgcgggcgg cgtcccggcc gtcggcggtc accgcccagc ccggctccag
      541 ggcgtcgccc cgctcccggg ccttcttgac cttcgagtag gagacctggc tggtggccat
      601 gtcgatgcac agcatctcgc cgccgtcgcc ctgcaccgcc atggacagcg ggttggtgcc
      661 gaagaagggg cggctgccgc cgaagggggc gaccagggcg tcgctgttgg tgaaggacag
      721 gccgaggcag ccccggtccg ccatctccag ggtgtagacg gaggcggcgc cgaaatgatt
      781 ggagttggag acggcgacgg cgccgacgcc gtggcggccg gccagccgcg ccgcctcccg
      841 ggcggcgagg gtgccggcga tgacgcccaa ggcgccgcca gcgtcgaggc ggcggccggc
      901 gcggcccggg acggggcgcg ccggctccga cgcctgccct gccccctctt ctgccgccgc
      961 cacctgccca tccggccccg caccgtgcca ggtcagctcc ggctcggccc gggcccggcc
     1021 gccgtcaagc tccgccaggt aggtcgggaa gaggcggacg ccgtgggtgt cgatgccgcg
     1081 cagggaggcg cgcagcaggc catcgaccat catccgccgg tgctccgccg gcacgccccg
     1141 gcgctccagg gcggcctcca tcaggcggtc gagatcggcc accgggacgc gcgccgcgcc
     1201 ctccgccgtg gcgccggggg cggtgtcacg gcctgcggtg tcccggcctg cggtgtcccg
     1261 gcctgcggtg tcctgccccg gcgtgcccac cgccccgctc acgccgcgca ccgctcggcg
     1321 acgaacgccg ccagccgctc gacgcccaag tcgatctcct cgggggagac gtagctgaac
     1381 gacagccgca cctggtgctc gtggccgggg gtcagggaaa aaaacgacag cgggcagacg
     1441 atgaccccgg cctcgccgga ggcggcctcc gccaccgccg cctcgccgaa ctcgaacggc
     1501 aaatcgaggg tgaggaagaa gccgccgccg gggacgttcc agcgcacccg gtcgagcagg
     1561 tcgcgctcgc cgaagctctt ctccagcgcc gccaccatgc ggtcccggtt gcggcggtag
     1621 aaggggatct tctcccccac caggcgggcc agggagaagt cctcgtccac caggatgccg
     1681 ccggcggcgg cctgcatcgg cgccggggtg ttgacggtca ccaggctctt gaccggggac
     1741 agcgcctcgg ccagggtcgt gccggccgcg ccctccaccg cctggtccgc caccatgtag
     1801 cccagccgca ggccggggaa cagggtcttt gaaaagctgc ccaggtaaac cacccggccg
     1861 taggggtcca gcgccttcag ggtcgggcgg gccggctggt cgtaggcgaa catgcggtag
     1921 ggattgtcct cgaagaccag caggtcctcc tcctcggcca actccagcag gcgcagccgg
     1981 gaggccaggg ggaggctggt gcccagcggg ttgttgaagt cggggatgtc gtagatcgcc
     2041 cgcggccgct tgccggcggc acgcacccgg gcggcggcct cggcgacgcg ctccggctcc
     2101 aggccgtcgt cgccgcaggg caccggctcg acgtccacct ccagcacccg ggccaggccg
     2161 gtgatgccga tgtaggtggg gttgctgacc agcagcacgt cgcggcccgg ctcgaacagg
     2221 cccatcagca ggatcgccat cgcctcctgg caaccgcagg tcaccatgat ggaggagggc
     2281 gccacgtcga tcccctcgtc ggcctgcagg tggcgggcga tggcgtcgcc gaggatgccg
     2341 ttggtgcggc cgtactggcc gaggtcggcc agcagctcgc cccgggggcg ctcctcctcg
     2401 gcggcgcggt gatcgaccca gcggccgacc ccgcccagcg cctgctcgac gtcgaagagg
     2461 tcttcccagg ggcggcccgg ggcgaaggag atcgcctgcg ggtagcggga gaccacctcg
     2521 ttgaggaagt tcatgacgcc gagggagggg tgggccaggg agtggcgcac ggccaccgtg
     2581 gtcacccggc cctgccccgc cgtggcccgc ttcacatctg cctcattcga tgtcatgacc
     2641 gccattccat cacctcccac gacctgccgc gaccggcctc agtaggaacc gctctcctcc
     2701 aactggcgga acagctcggc gacgctctcg tcggtgaagt ggccgtcctt ctcctggcgc
     2761 tcgatgagct cgtacatcat gccggaggcg gggtcccggt gggtgaagga ctggcggatg
     2821 ccggcgccct ggatcaggtt ggtgtcgaac tcgacgccgc tctccttcag acgctccatg
     2881 acctggggca ggtccttgac ctcgaaggcg atgtgctgca cgccggcgcc gtactcggcg
     2941 acgtacttcg acacctggga ctcctcgctc aggccctgca ccaggaccag gacgatggga
     3001 ccggccttga tgacggcgga ggtcatgccg gtgaaggcgc ccttggtctc gcggcgctcc
     3061 agcacctcga agccgaggtt gtcgcggtag aagaccacgg ccttctccag gtcggggacg
     3121 gcgatggcga cgtgatcgag gcccacggcg aggtcggcga ggacggaagc ggtctgggtg
     3181 gtcatgacgg ggactccctt tggggattgt tgttcagtgc aaggttgatc gaaacaatgg
     3241 atcttctgga ggccgggcgg tagcccggaa ttgggggacg gctactgttc gagtgcggct
     3301 cgcgcccggc ggcgggactg ttcggggcca ccgaatgtga ataaaccttt ctctaaagtt
     3361 caccgaggct cactgatcga tggatcaagg ctcttccgag gcccccgtct ccccgtcgcg
     3421 gagctgaccg tcgagcagcc gggcgacgcg ggcggcgccc ttctccgggg catcccgcag
     3481 cacgctgaag tggtcccccg gcaccgcctc gacccgcagg ccgtcgccca ggagggggcg
     3541 ccagaaggcg ctgggcaggg ggcggccggg cagcgcctcg gcggcgtcca ggagcagcac
     3601 cggtcccggg tacgcctcgg ggcggtacga ctccagcgcc tcggcatggg cgcggaagac
     3661 gcgccagcgg cgctccaggc cggcggccaa ctcgggcgac agcaggccgc tctcccggcc
     3721 ggcctcggcg tagcgcgcca gggcccggga cggggtggcg gcggccagct cccgcagcgc
     3781 cgcctcgccg ccgaggccga cgtcggccag cggcgccccc atctgctggg cgaagctggc
     3841 cagggtcacc aaccggccgg cgtcgtcttc cggcatggag ttactagaag cggcgtccct
     3901 cgaagcggcg tccctcgaag cggtgcgcct cgaagcggtg ccccttgacg cgctgctgtg
     3961 gggcgcggcg tcgatcaggc tgagggagag gggggccgct ccctggcgct ccagccgtcg
     4021 ggccatctcg taggccacca ggccgcccag cgaccaaccc gccaggtgga gcggcccggc
     4081 ggggaggcga ccgtcccgcc gcgcccggcc caactcctcc aggtagtgcg ccgccatcgc
     4141 ctcgacccgc gccagcggct cggcggcgcc gtccagggcc gggtcccgca ggccccacac
     4201 cgggcgcccg ccggcaagct cccgcaccag cgggacgtag gcgaggaggt cgccgccgcc
     4261 ggggtggacg aggaccaagg gcgccgcgtc gctggcgccg ggagccaggc gcaccaggca
     4321 gccgccggca tccccggcag ccccggcgtc gtcagcgtcg ccgcggcgct ccagctcggc
     4381 ggccagcagg cgcaccgtgg gtgcctggaa cagggtcgcc agcggcaccg gctgccgcag
     4441 gcgggcgacc aggcgcaccg ccagcaggga gtggccaccg gcgaggaaga agtcgtcatc
     4501 gacccccacc cgctcgacgc ccagcacctc ggcgaacagc gccgccaggg tctcctccag
     4561 cggcgtcgat ggcggcgtgt acccaccggc ggcgcgctgc ggctcgatgg cggccagggc
     4621 gcggcggtcg atcttgccgt tgggggtcag gggcagctcg tccagcacga cccaggccga
     4681 cggcaccatg tagtccggca gcgaggcgcg caggtggcgg cccagctccg ccgggtcggg
     4741 gccgggcccc gactccgcgg acacgtaggc cgccaggctc ttgccgtcgg cggtgtccct
     4801 cgccagcacc gcggcctcgc gcaccgccga atgggccagc agcgccgtct cgatctcccc
     4861 cagctcgatg cggaagccgc gcaccttgac ctggtggtcg aggcggccca agtagtccag
     4921 taaagcagtg tcgagttgcg ccgtgtccag ttgcgctgtg tcgagtagcg ccgtgtcgag
     4981 ttgcgccgtg tcgagtaacg cctgggcgct cccggccgcc ccgcccggca gccagcgcac
     5041 cagg
//
