LOCUS       c00022_3300026..       22705 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300026518.a:Ga0256829_1000053.
ACCESSION   c00022_3300026..
VERSION     c00022_3300026..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 16:55:22
            Original ID  :: 3300026518.a:Ga0256829_1000053
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 99567
            Orig. end    :: 122272
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22705
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[109567:112272]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12705
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     cand_cluster    1..22705
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22705
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     CDS             complement(639..1862)
                     /gene_functions="transport (smcogs) SMCOG1282:extracellular
                     ligand-binding receptor (Score: 227.2; E-value: 4.6e-69)"
                     /gene_kind="transport"
                     /locus_tag="ctg22_94"
                     /transl_table=11
                     /translation="MTYMKKTLAASIAVAAASSMAISTAHAEISDGEVRIGYLADMSGT
                     YRDLAGPGGQTAMEMAVADFGGSVNGSPIVIFSADDRNSADVGANTVREWIDQRNVDMV
                     GGLVASSVSIAVTKVLQENNGLGIVSGSAASSITNEHCTPNHIHWVYDTYPLANGTAKA
                     VVELGGDSWFLLTADYAFGHALEADVTSVVEANGGEIVGGVRHPFPTSDFSSYILQAQG
                     SGAKIVGLANAGADTVNAITTASQFGLTQSGQQLAGLLIFLNDVHALGLEATQGLLLTT
                     GWYWDMDEESRAWSERYFEETGRMPTMVQAGIYSSTMHYLKAVEAAGTDDPETVRAKMA
                     EEPINDFFARNGSIREDGRMIHDMYLAQVKTPEESTGEWDLYEILSTIPAAEAYRPLSE
                     SQCSLVQN"
     CDS             complement(2010..2759)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 147.2; E-value:
                     1.1e-44)"
                     /gene_kind="transport"
                     /locus_tag="ctg22_95"
                     /transl_table=11
                     /translation="MNTAEVFESQEAPEHQTLEMLRVQDLHAFYGESHILHGVNFDVKR
                     GELVTLLGRNGAGRSTTLKAIMNMVGRRTGSIVINGNETLRMKPHHIPRLGIGYCPEER
                     GIFASLDVHENLLLPPTVRSGGMSLDEIYGMFPNLYERRKSQGTRLSGGEQQMLAMARI
                     LRTGARLLLLDEITEGLAPVIVQKLGEVLVQLKERGMTIVLVEQNFRFAAPLADRHFVM
                     DHGQIVEEITAEQLPSRREHLNSMLGV"
     CDS             complement(2756..3541)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 179.9; E-value:
                     1.1e-54)"
                     /gene_kind="transport"
                     /locus_tag="ctg22_96"
                     /transl_table=11
                     /translation="MRADEVTKGPVLETRGLTKEFCGFTAVDNVNLQVQEGHIHALIGP
                     NGAGKTTVFNLLTKFLPPTRGEILYRGQPITSKKSNEIAQLGLVRSFQISAVFAHMTAL
                     ENVRVALQRQLGTSFHFWKSEKTLDHLNDRALALLDEVGLREYADTLTVEMPYGRKRAL
                     EVATTLALDPSMMLLDEPTQGMGAEDVDRIVALIKRVSQGRTVLMVEHNLSVVSRLCDR
                     ITVLARGAVLAEGDYDTVSRNPLVREAYMGSEAAEEAAV"
     CDS             3853..4257
                     /gene_functions="regulatory (smcogs)
                     SMCOG1171:transcriptional regulator, MerR family (Score:
                     81.9; E-value: 1.2e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg22_97"
                     /transl_table=11
                     /translation="MSKTYSISELASEFDVTTRSIRFYEDQELLHPTRRGQTRIYSSKD
                     RVRLKLTLRGKRLGFSLAEIRELFELWDETRSGSEKQLHLMLSKISERKAALEQQMKDI
                     TMVQLELESAEIRCRQALEELNEKHPATAK"
     CDS             4307..5476
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 401.9; E-value:
                     4.7e-122)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_98"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 8.3e-39, bitscore:
                     126.0, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 5.1e-30, bitscore:
                     96.9, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.7e-44, bitscore:
                     144.9, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFSHYSELNFGLDDELNMLREQVNAFAASEIAPRAAEIDHNNEFP
                     NDLWKKFGDMGLLGITVPEEDGGSGMGYLAHCIAMEEISRASASVGLSYGAHSNLCVNQ
                     LKINASAEQKAKYLPKLMSGDHVGALAMSEPGAGSDVVSMQLRAKEDGDHYILNGNKMW
                     ITNGPDADVLVVYAKTDPDAGSKGITAFIIEKGMPGFSTAQKLDKLGMRGSNTCELVFQ
                     DCRVPAENVLGEVGKGVRVLMSGLDYERTVLAAGPIGIMQAAMDIVIPYIHERKQFNQS
                     IGEFQLVQGKVADMYTTLNACRAYLYAVAAACDRGQTSRKDAAGVILYCAEKATQVALD
                     AIQLLGGNGYINEYPTGRLLRDAKLYEIGAGTSEIRRMLIGRELFTESL"
     CDS             5499..7106
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059:acetyl-CoA carboxylase, carboxyl transferase,
                     (Score: 515.9; E-value: 2.2e-156)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_99"
                     /transl_table=11
                     /translation="MSTLSTQINPRSDVFQANEAAMLGEVNKLRELTAAIAQGGGEKAR
                     ARHESRGKLYVRDRIDHLIDEGSPFLEFSALAAHHVYDSEVPAAGVITGIGRVSGVECV
                     IVANDATVKGGTYFPLTVKKHLRAQEIARKHRLPCIYLVDSGGAFLPRQDEVFPDRDHF
                     GRIFYNQATMSAEGIPQIAVVMGSCTAGGAYVPAMADESIIVKEQGTIFLGGPPLVKAA
                     TGESISAEDLGGADVHAKVSGVADHYAENDAHALQLARACVSRLNWQKRGQLAMQPPRP
                     PKLDPSELYGIVGTDLKKPYDVREVIGRIVDGSDFDEFKRYYGDTLVTGFAHIHGYPVG
                     IVANNGVLFSESAVKGAHFIELCAQRKIPLVFLQNITGFMVGSKYEHEGIAKHGAKLVT
                     AVACANVPKYTVLIGGSFGAGNYGMCGRAYDPNLLFMWPNARISVMGGEQAAGVLSQVK
                     REQYEREGREWSKEDEEAFKKPTRDQYEHQGHPYYASARLWDDGVIDPLQTRDVLGLSL
                     AAAMNAEVKETRFGVFRM"
     CDS             7119..7943
                     /NRPS_PKS="Domain: ECH (7-252). E-value: 1.2e-44. Score:
                     144.1. Matches aSDomain: nrpspksdomains_ctg22_100_ECH.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023:enoyl-CoA hydratase (Score: 207.5; E-value:
                     3.1e-63)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_100"
                     /transl_table=11
                     /translation="MAYSTLVIEAGIARLTLNRPEVHNAFDDSLIAELNAHLEKLHGLV
                     SAGDVRVVVLGSEGKSFSAGADLNWMKRMVDYDLEDNLADSRKLAALMHGLDTLPCPTI
                     CRVQGAAFGGAVGLAACCDIVVASEKAKFCLSEVNIGLSPAVISPYVQRALGQRQMRRY
                     ALTAEVMDAPTALSLGLAHQVVEHDALDNAVDSMIATLVKGSPQAQRATKALLATVAQA
                     PDADATREHTCQVIAKLRVSQEGQEGLASFLDKRRPAWTSPEEHNNAAEPRS"
     aSDomain        7140..7874
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg22_100_ECH.1"
                     /evalue="1.20E-44"
                     /label="ctg22_100_ECH.1"
                     /locus_tag="ctg22_100"
                     /protein_end="252"
                     /protein_start="7"
                     /score="144.1"
                     /tool="antismash"
                     /translation="IEAGIARLTLNRPEVHNAFDDSLIAELNAHLEKLHGLVSAGDVRV
                     VVLGSEGKSFSAGADLNWMKRMVDYDLEDNLADSRKLAALMHGLDTLPCPTICRVQGAA
                     FGGAVGLAACCDIVVASEKAKFCLSEVNIGLSPAVISPYVQRALGQRQMRRYALTAEVM
                     DAPTALSLGLAHQVVEHDALDNAVDSMIATLVKGSPQAQRATKALLATVAQAPDADATR
                     EHTCQVIAKLRVSQEGQEGLASFL"
     CDS             7940..9991
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090:acetyl-CoA carboxylase biotin carboxylase (Score:
                     706.7; E-value: 5.5e-214)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_101"
                     /sec_met_domain="ATP-grasp (E-value: 2.2e-10, bitscore:
                     33.6, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFTPTKFDTLLVANRGEIACRVMRTALRMGLKTVAVYSDADATS
                     RHVREADEAVRLGPAAARESYLNVDAVIEAAQRTGTGAIHPGYGFLSENGTFVKALEQA
                     GITFVGPPASAIAAMGDKSAAKARMANAGVPLVPGYHGDDQGDALLRSEADKIGYPVML
                     KASAGGGGKGMRVVESGEGFQAALDGCRRESKAAFGDDRMLLEKYLVQPRHVEVQVFCD
                     RYGNGVYLFERDCSVQRRHQKVIEEAPAPGMTTELRAAMGDAAVRAAQEIGYVGAGTVE
                     FLLDSSPGQDGAFYFMEMNTRLQVEHPVTEMITGQDLVEWQLRVAMGEPLPCRQDELTI
                     TGHSFEARIYAEDPEQDFLPATGLLTRFALDLEGAGLGADQVRLDSGVESGDTVSMHYD
                     PMLAKLIVHGVDRDAALATLNRALASLDVQGVVTNRAFLQRLANHPGFKNVELDTRFIE
                     RNEATLFAPRQFSTEDYASAALIGLHQLAQECESDSPWGRHDGFRLNAPHTIRIALCDP
                     ASAQAADNDSAVVVVEGKRATLDTQWQLTIGNSTLTASLQPLEGDAVAVTLNGHRRRLQ
                     AYKDGHVVVMAEPSGETRLFWRRIDAIDHGHHETESTLTAPMNGTVVALLVEPGAQVEK
                     GMPLMVMEAMKMEHTMTAPADGSVETFHFQAGDTVSQGAVLLDFAPSE"
     CDS             10001..10918
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 215.7;
                     E-value: 2.1e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_102"
                     /sec_met_domain="HMGL-like (E-value: 2.6e-58, bitscore:
                     190.8, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALPTSIKLFEMAPRDGLQNEPGTLVPTATKIELIERLANAGIRH
                     IEAASFVSPKWVPQMGDAAEVMRGIQRQHGVVYSALTPNLKGLEGALEAGVEEVAVFGA
                     ASEAFSQKNINCSIAESLARFEPVLSRANEVGVRVRGYVSCVLGCPYEGDIAPHKVADV
                     AKALYEMGCYEVSLGDTIGVGTPLATKRMIEATRQQVPIEKLAAHFHDTYGMAIANLYA
                     VLEEGVSVIDAATAGLGGCPYAKGASGNVATEDVLYLLEGLGIDTGIDLQVVIGTGYWI
                     TRQLGRQPSAKVALARGCTQRTPG"
     CDS             10993..12705
                     /NRPS_PKS="Domain: AMP-binding (31-465). E-value: 7.4e-109.
                     Score: 355.7. Matches aSDomain:
                     nrpspksdomains_ctg22_103_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 413;
                     E-value: 2.4e-125)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_103"
                     /sec_met_domain="AMP-binding (E-value: 4.5e-117, bitscore:
                     384.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASSAPLSSALPSYTSSTADKPLLGMTIGDKFDQIAAQYPDNDAL
                     IALHQNIHWSYRELQQEVNRCARALLAIGVQKGDRVGIWAPNCSEWTLTQFATAKIGAI
                     LVNINPSYRTHELEYALNQSGARFLVTANQFKSSDYTAMLFELAPELNNCAEGQLKSQK
                     LPELECVINLSADKHSGMWRWADFIAEADKVSQTDVDDLQATLQFDDPINIQYTSGTTG
                     FPKGATLSHHNILNNGFFVAESMGFTSEDRLVIPVPLYHCFGMVMGNLGCVTHGAAMIY
                     PDEGFDPGKVLKAVHEQKATALYGVPTMFIAELEHPDFASTDFSTLRTGIMAGSICPAE
                     IMKQVINKMNMKGVQIAYGMTETSPVSTQTGANDTIEKRVSTVGRTQPHLESKIVDPGN
                     GGILPRGEIGELCTRGYSVMLKYWNNDKATAEAIDETGWMHTGDLATMDDEGYIQIVGR
                     IKDMVIRGGENVYPKEIEEFLYAHPAISEVQVTGVPDKKYGEELIAWVKLNSTAGEITG
                     EDLREYCKGKITHFKIPRYFKFVDEFPMTVTGKIQKFKMREISIKELGLEDQK"
     aSDomain        11086..12387
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg22_103_AMP-binding.1"
                     /evalue="7.40E-109"
                     /label="ctg22_103_AMP-binding.1"
                     /locus_tag="ctg22_103"
                     /protein_end="465"
                     /protein_start="31"
                     /score="355.7"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FDQIAAQYPDNDALIALHQNIHWSYRELQQEVNRCARALLAIGVQ
                     KGDRVGIWAPNCSEWTLTQFATAKIGAILVNINPSYRTHELEYALNQSGARFLVTANQF
                     KSSDYTAMLFELAPELNNCAEGQLKSQKLPELECVINLSADKHSGMWRWADFIAEADKV
                     SQTDVDDLQATLQFDDPINIQYTSGTTGFPKGATLSHHNILNNGFFVAESMGFTSEDRL
                     VIPVPLYHCFGMVMGNLGCVTHGAAMIYPDEGFDPGKVLKAVHEQKATALYGVPTMFIA
                     ELEHPDFASTDFSTLRTGIMAGSICPAEIMKQVINKMNMKGVQIAYGMTETSPVSTQTG
                     ANDTIEKRVSTVGRTQPHLESKIVDPGNGGILPRGEIGELCTRGYSVMLKYWNNDKATA
                     EAIDETGWMHTGDLATMDDEGYIQIVGRIKDMVIRG"
     aSModule        11086..12387
                     /domains="nrpspksdomains_ctg22_103_AMP-binding.1"
                     /incomplete
                     /locus_tags="ctg22_103"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       11632..11685
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_103_0001"
                     /evalue="1.40E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg22_103"
                     /protein_end="231"
                     /protein_start="213"
                     /score="17.8"
                     /tool="antismash"
                     /translation="IQYTSGTTGFPKGATLSHH"
     CDS_motif       12202..12288
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_103_0002"
                     /evalue="6.30E-07"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg22_103"
                     /protein_end="432"
                     /protein_start="403"
                     /score="21.8"
                     /tool="antismash"
                     /translation="PRGEIGELCTRGYSVMLKYWNNDKATAEAI"
     CDS_motif       12358..12420
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_103_0003"
                     /evalue="6.60E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg22_103"
                     /protein_end="476"
                     /protein_start="455"
                     /score="12.5"
                     /tool="antismash"
                     /translation="VGRIKDMVIRGGENVYPKEIEE"
     CDS             12816..13646
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 95.4; E-value:
                     6.2e-29)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_104"
                     /transl_table=11
                     /translation="MPTSLAHHYHQALRDQDILNQLSSHYPDGPTLHQLAPLDQLHIGG
                     IAASKRLLDLLDQSAPMALDIGAGLGGLMRQGAALGFHLTGLDITHRFNVLNQAISELA
                     MTQPPNDSSAGTLRCVTGDACALPFSDASFDAVLFQHSLMNMPDPARVLAECRRVLRPG
                     GQLVMHEVVSGPHCEALRFPVPWAEGPTHSHLLTLAALTQRLQTAGFDIRHCEDWSHTA
                     LKWRQRQRQKEQPPRTGVLSPQWVFGERFMCMGKHLLENLANGAINVVEISARC"
     CDS             13691..14260
                     /locus_tag="ctg22_105"
                     /transl_table=11
                     /translation="MNRLASTLLLSLFGTLLPLEATLADDDAPALSYAAPNSEWMRLDN
                     GVVLEGSDLSSLDTNTTGFRLTAGFSPEQLPRLDIGAEIAYRESEEVPITSQMNPLLMD
                     TLSLGGALVAGVRMGAVSIYAKSGFTEWRGEAYQPQTDDGGTALLQGFGATMTINRLIS
                     RFEYERIDAATLSHLNMLSASLHLPF"
     CDS             14376..14645
                     /locus_tag="ctg22_106"
                     /transl_table=11
                     /translation="MPLSPSHYQTELVRHLVAIETPEAMDAALASLLTPAEYQEISKRL
                     QIFKLLNEGMPHRKIADTLGVGIATVSRGSRALNQSSSSRNAPL"
     CDS             14642..16063
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018:isochorismate synthase (Score: 271.2; E-value:
                     3.7e-82)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_107"
                     /transl_table=11
                     /translation="MSTHTQANTPGPTPFTLPRKPHYVTLAADCDFFALFQKIERRFDT
                     CYMLESLGEDSHMARHSIIGFDPEYTLYANGHTLTIENRDGQAEQYTSENPYELLRSLI
                     PQNIISRKYAGGLSGYLGYDAMQYFEPSLTLKASDDFDTFRFGLYKDGLILDKMTGEVT
                     YFYYDNSRYAFLQTLIDADDEPAGPLHITALGDTMSKAEHAAAVAKVKQDIIDGKVFQC
                     EVGFKKRFRIQGDTLALYDQLRTINPSPQMYYVKFGEQKLIGASPELLFRLRQGEMETF
                     PLAGTTLRGQTPQEDTQLARALLNDPKEIAEHNMIVDLHRNDIGRVAQFGTVKVRSLMD
                     IKRFSHVQHISSEIVGIIAESEDMFTALASNFPAGTLTGAPKIEAMKIIDDLETDGRGP
                     YGGAVGQFSFNGDCTFAIPIRTVFVNGERAYVQTCGGNVYDSNAEDEYEEIRRKFAGTR
                     KALAPFMDTETESPA"
     CDS             16060..16734
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1249:carbamoyl phosphate synthase small subunit
                     (Score: 119.4; E-value: 2.6e-36)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_108"
                     /transl_table=11
                     /translation="MKVLIIDNYDSFTYNLYQFIGEILTTEKNRGELPHFEIMVKRNNQ
                     IDFKAIEAMAPDRIIISPGPGSPDDPRYFGVCAEVIEKLGKTTPLLGVCLGMQGIVHVF
                     GGKVVKAPLPMHGKISPINHNNQSVFNGVPDQLEVMRYHSLIADAATLPECLEVTATVG
                     ALTADNFAERGRWQAAGEFELMGVKHRDYPIHGIQFHPESFATEGGKELIANFLFAPNA
                     AA"
     CDS             complement(16718..16993)
                     /locus_tag="ctg22_109"
                     /transl_table=11
                     /translation="MSYLLAWYATASVITYVLYAWDKRAAIKQRQRVSEKTLHWLALLG
                     GWPGAWCAQQQLRHKTQKTSFRRVYWATVLLNIAVLGGFVAVMPLR"
     CDS             complement(17021..18097)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1154:Pseudouridine synthase (Score: 291.5; E-value:
                     5.4e-89)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_110"
                     /transl_table=11
                     /translation="MSLRKSTRINKYISESGLCSRREADRFVEQGNVWINGRRATTGDQ
                     VVAGDRVKVNGQEIEPQEEEDLVLIALNKPVGIVSTTESAEKDNIVEFVKHGTRIFPIG
                     RLDKDSQGLIFLTNNGDLVNKILRANNNHEKEYVVTVDKPITNEFIAGIQGGVPILGQM
                     TKKCQVVKESTFVFNITLVQGLNRQIRRMCEYFGYEVTQLVRTRIMNVSLKGLALGDWR
                     DLTPKEIETIVALTETSDVAPEKKTSEKKAPEKKKIARPNYSGGRSSAQDKKTAAKRAS
                     SGAGAGNKARKDPKAKGAAAGKSGGKGAVSAGRPATKGKGRPGSHSSGKPGARKGAIKG
                     GRPSGGKAASGKPPSRRK"
     CDS             complement(18124..18321)
                     /locus_tag="ctg22_111"
                     /transl_table=11
                     /translation="MTTDAQAVLAFWFQELSPAQWFKKDAQIDQQIIDRFGRYPHRNAV
                     LGRASTPEEVEFLKQPGSSF"
     CDS             complement(18398..21046)
                     /locus_tag="ctg22_112"
                     /transl_table=11
                     /translation="MSHDLHESLRDNVRILGDSLGRTIADDLGQSFVDKIETIRAHAKR
                     GRQGDSLQQRQLIEYLRQLPERDLLPVTRAFNQFLNLANIAEQHYRARFRRVEDYKPGS
                     QPALGELLARAQQVGNSPRKLVETLANMRVELVLTAHPTEVIRRTLIQKYDAIDECLTA
                     IESSEDYPERGARAQGRLEELISQAWHTDEIRHERPTPVDEAKWGFAVIENSLWQAVPD
                     FHRDLDNLLLDTAGERLPLDAAPIRYASWMGGDRDGNPNVTAKVTQEVLLLGRWMAADL
                     YLRDLEQLKTELSMWKANSALKAEVGDVAEPYRELLKRLLTKMEATRDWAKAQLDGRNY
                     DGGPIIETRDQIYAPLLACYRSLCDVGLDTIANGALLDTLRRVAVFGVTLTKLDLRQEA
                     SRHAQVMEELTSSLGLGHYQEWSETQRQEFLLAELESRRPLIPRRWECSAESREVIDTF
                     KVIAQEHAEALGTYIISMAAEPSDVLTVALLMKEVGGQVTLPIAPLFETLNDLDHAGDV
                     VDQLLALPGYRALTKDRQEVMIGYSDSAKDAGQLAAAWAQYRAQEALVNVCEKHGVDLT
                     LFHGRGGTVGRGGGPAHAAILSQPPGSVNGSLRVTEQGEMIRFKFGQPDIALRSMEIYA
                     CAVLEATLLPPPAPEPHWREEMDQLAKVAHAAYVGVVREDPDFVPYFRAVTPEGALGRL
                     PLGSRPTKRRQDGGVETLRAIPWIFAWTQIRLMLPAWLGSGEAFSRRLEQPGGREVLQE
                     MRTQWPFFGTYLDMLEMLLAKADVAIAAYYEHRLVDEPSLKALGKKLRERFERLEDVVL
                     DILQQEKLLENTPLIRQAIDVRNPYIDPLHGLQAELLQRNRDADGAISPDLSRALMVTM
                     AGIAAGLRNTG"
     CDS             complement(21088..21915)
                     /locus_tag="ctg22_113"
                     /transl_table=11
                     /translation="MRHTLDDLLTLMAVLRDREQGCPWDIQQDWDSIVPHTLEEAYEVA
                     DAIERRAFDELPGELGDLLFQVVYYAQFGAEEQRFDFHDIVDTLTAKMLRRHPHVFPDG
                     TLASRRPTGVSADEVKTQQVNSRWEALKADERAKRATQPPSVLDDVPRTLPALSRAAKL
                     SKRAARVGFDWSNAEGVLAKIREELEEVEEALAAGDRQHAQEEVGDLLFAVTNLARTLG
                     ADPEQCLRNTNTKFERRFRYVERALAEAERPLSEASLDEMEGHWQAAKAQEQR"
ORIGIN
        1 gaatagacac atggccagcg ccgccactaa cacccaagca cggtaggtag gtaagaacat
       61 aaagcccaga ttaaggccgc cctgcagaat ttcaggggta gcgtagcgcg ccccagaaac
      121 gccgaataag ttaattaatg tgccttcgaa aatcagcgcc aacccgaagg tcagcagcag
      181 cccgtagagg tggtcgaggt gggcaatgcg acgcagcaga aagcgctcca tcagcatgcc
      241 gcaaccaccc accaccagcg ggactaaaat cagtgctagc caatagttaa tgcccaggta
      301 gcgaaagcct agcagcgcgg cgaaggctcc cagcatgtac tgcgccccgt gggcaaagtt
      361 gacgatcttc agtaggccga agatgaccgc caggcccaaa ctaagcagtg cgtaaaaggc
      421 accgttcaca agcccaagcg ttagctggcc catgaacacg gccattggca cgccgaatat
      481 catcgtcatg gtatgactct cctcgccgct aagcgggcag ccctatgggg ctgccccagc
      541 gcgttgctta ttgttagaaa cgcctttcat cacgccttta cggcttgctt ggcccaggcc
      601 aaggcagcag atgcctgagc ctggagcgcg tcagcagatc agttctgtac cagtgagcac
      661 tggctttcag acagcggacg gtaggcttct gcggcgggaa tggtgctaag gatctcgtag
      721 aggtcccact caccggtaga ctcttccggc gtttttacct gggctaggta catatcgtga
      781 atcatacggc catcttcacg aatgctgccg ttacgggcga agaagtcgtt gatcggctct
      841 tcggccattt tcgcgcgcac ggtttcgggg tcatcggtgc cagcggcttc cacggctttc
      901 aggtagtgca tagtgctgga gtagataccg gcttgcacca tggtgggcat acggccggtt
      961 tcttcaaagt agcgctcaga ccaagcgcgg gactcttcat ccatgtccca gtaccagccg
     1021 gtggtcagca gcagcccttg ggtggcttct agccccagcg cgtgtacgtc gttgaggaag
     1081 atcagcaggc ctgctaattg ctggccgctt tgggtcagac caaactggct ggcagtggta
     1141 atggcgttga ccgtgtcggc accggcattg gcgaggccaa cgattttcgc gccagaaccc
     1201 tgcgcctgaa gaatgtagga ggagaagtcg ctggtgggga acgggtgacg cacgccgccg
     1261 acaatttcac cgccattggc ttctaccacg ctagtcacgt cggcttccag tgcatggccg
     1321 aaggcgtaat ccgcagtgag cagaaaccag ctatcgccgc ccagctcaac gacggccttc
     1381 gcggtgccgt tggccagcgg ataggtgtca tacacccagt gaatatggtt cggagtgcag
     1441 tgttcgttgg taatgctaga cgccgccgag ccggagacga tgcccaggcc gttgttctct
     1501 tgcaacactt tggtcacggc gatagacaca gacgacgcca ctaagccgcc aaccatatcg
     1561 acgttacgct ggtcgatcca ctcgcgcacg gtgttggcac ccacgtcagc actgttgcgg
     1621 tcatcggcgc tgaaaatcac aatgggcgag ccgttcacgc tgccgccaaa atcggccacc
     1681 gccatttcca tcgcagtttg gccacctggg ccagccaaat cacggtaggt gccggacata
     1741 tcggctaagt agccaatacg cacttcacca tcgctgatct cggcgtgggc ggtcgagatc
     1801 gccatgctgg aggcagcggc aacggcgatg ctggcggcca gcgttttctt catataggtc
     1861 atgttcgtct cctggccctc agggcctttg tttttatgat gcggacgttc agttatagcg
     1921 tttgtgtgtg tggagcgctt gtgtatggaa cgtaagtgtt gcgtttgttg ttctttaagg
     1981 ccgtgcttac agtttagatg gtgtgcgatt tataccccca gcatgctgtt taaatgttcc
     2041 cgccgggaag gcaactgctc agcggtgatc tcctcaacaa tttggccgtg atccatcaca
     2101 aagtggcggt cagccagcgg ggcagcaaag cggaagttct gctcaaccag cacgatggtc
     2161 atgccgcgct cttttagctg caccaatacc tcgcccagct tttgcacgat gaccggcgcc
     2221 aagccttcgg tgatttcatc cagcagcagc aagcgcgcac cggtacgcag aatgcgcgcc
     2281 atggccagca tctgctgttc gccgccggag agccgcgtgc cctggctttt gcgacgctcg
     2341 tagaggttcg ggaacatgcc gtagatttca tccaagctca ttccgcctga acgcacagtg
     2401 ggtggcagca gcaggttttc gtgaacatct aagctcgcaa aaataccgcg ctcttccggg
     2461 cagtagccaa tgcctaaccg gggaatatgg tgcggcttca tgcgcagggt ttcattgcca
     2521 ttaatgacaa tcgaaccggt gcgccgcccg accatattca taatcgcttt tagcgtggtg
     2581 ctgcggcccg cgccgttgcg gcccagcagg gtcaccagct cgccacgctt cacgtcgaaa
     2641 ttcaccccat gcagaatgtg cgattcgcca tagaaggcgt gcaggtcttg cactcgcagc
     2701 atctctaggg tctggtgttc tggggcttct tggctctcga atacttctgc ggtattcata
     2761 cggcagcctc ctcagccgct tcgctgccca tataagcttc acgcactaag gggttgcggg
     2821 aaaccgtgtc gtaatcccct tctgccagca ccgcgccccg cgccaatacg gtaatacggt
     2881 cacacaagcg gctgaccacg ctcaggttgt gctccaccat caacaccgtg cggccttggg
     2941 aaacccgttt gatcagcgcc acgatgcggt caacgtcttc cgcgcccatg ccctgggtcg
     3001 gctcgtctag cagcatcatg ctggggtcca gcgccagcgt ggtggccact tctaaggcgc
     3061 gcttgcggcc atagggcatt tccacagtga gcgtatcggc gtattcgcgc agacccactt
     3121 catcgagcag cgctagagcg cggtcgttga ggtggtccag cgttttttcc gatttccaga
     3181 agtggaacga cgtgcccagc tggcgctgaa gcgctacgcg cacgttttcc agtgcagtca
     3241 tgtgggcaaa caccgctgaa atctgaaacg aacgcactaa gccaagctgg gcgatctcgt
     3301 tggatttttt gctggtgatg ggttggccgc gatagagaat ctcgccccgc gtagggggca
     3361 aaaacttggt taacaggtta aagaccgtcg ttttccctgc accgtttggg ccaatcaggg
     3421 catgaatatg cccctcctgc acctggaggt ttacgttatc cacggcggta aagccgcaaa
     3481 actctttggt cagccctcga gtttcgagca ctggcccctt ggtcacttcg tctgcacgca
     3541 tgaggtagga cgcctcttgt tgttcttgta cggtgggaag cgaaactcgt tagccagcaa
     3601 cgcatcctta cctgaacgta aggtgtaagt gcaaactagc aaccccacac agggtattac
     3661 aattacaact ttggtctacg caccactctg atgcaccaaa ttaaagctta aaagccttta
     3721 tttatcagtt attttttaaa attcaacggt aactcactca ttgcaatctc agctttacgt
     3781 taacgtaaac ttgttttagc ctcatggtca gtgttccata gggacatccc cctatcgacg
     3841 agaataacga tcatgagcaa aacctactcg atcagcgaac tggccagcga gtttgatgtg
     3901 accacgcgta gcatccgctt ttatgaagat caggagctac tgcatcccac ccgccggggc
     3961 cagacacgta tttacagcag taaagatcgc gtacggctaa agctgacact gcgcggcaaa
     4021 cgcctggggt tttcgctggc ggaaatccgc gagctgtttg agctgtggga tgagacccgc
     4081 agcggcagcg aaaagcagct acacctgatg ctgagcaaaa tcagcgagcg taaagccgcg
     4141 ctggaacagc agatgaaaga catcacgatg gtgcagttgg agcttgaaag cgctgagatt
     4201 cgctgccgcc aagccctcga agagcttaac gagaaacatc cggccaccgc gaaataaaca
     4261 acctcaacga ataacgaccc gattaacaac gacaaggtga ttgaccatgt tttcccacta
     4321 ttcagaacta aatttcggtc ttgacgatga actgaacatg ctgcgtgagc aggtcaacgc
     4381 ctttgccgcc agtgagattg ccccacgcgc cgccgagatc gaccacaaca atgagtttcc
     4441 caacgacctg tggaagaaat tcggcgatat gggcctgctg ggcattaccg taccggaaga
     4501 agatggcggc agcggtatgg gctacttggc ccactgtatc gccatggagg agatctcccg
     4561 ggccagtgct tccgtcgggc tctcctacgg cgcgcactcc aacctgtgcg ttaaccagct
     4621 caagatcaac gcctccgccg agcaaaaagc caaatacctg cccaagctaa tgagcggcga
     4681 ccacgtgggc gcgctggcga tgtcagagcc cggcgctggc tccgatgtgg tctccatgca
     4741 gctgcgcgcc aaagaggatg gcgaccacta cattctcaac ggcaacaaaa tgtggatcac
     4801 caacggtccc gatgccgatg tgctggtggt gtacgccaaa accgacccgg atgccggctc
     4861 caaaggcatc accgccttta ttatcgaaaa aggcatgccg ggcttttcca ccgcccagaa
     4921 gctcgacaag ctgggcatgc gtggctccaa cacctgcgag ctggtcttcc aggattgccg
     4981 cgtacccgcc gagaacgtgc tgggcgaagt aggcaaaggc gttcgcgtat tgatgagcgg
     5041 cctggattac gagcgcaccg ttctggccgc tggccccatt ggcatcatgc aagccgccat
     5101 ggacatcgtc attccttaca tccatgagcg taagcagttc aatcaatcca tcggtgagtt
     5161 ccaactggtg cagggcaagg tggcggatat gtacaccacc ctaaacgcct gccgcgctta
     5221 tttatacgcc gtcgcggccg cctgcgaccg tggccaaact tctcgtaaag atgccgctgg
     5281 tgtcatcctc tactgcgctg aaaaagccac ccaggtcgcg ctggatgcca tccagctact
     5341 gggcggcaac ggttatatca acgagtaccc caccggccgc ttgctgcgcg acgcgaagct
     5401 ttacgaaatt ggcgcgggca ccagcgagat tcgccggatg ctgattggcc gcgaactttt
     5461 caccgaaagc ctttaacaaa aattagcagg ggcgcgccat gagcacactc tccacacaga
     5521 tcaacccgcg cagcgatgtg tttcaggcca acgaggccgc catgctgggg gaagtcaaca
     5581 aactccgtga actcactgcg gccattgcac aaggaggcgg tgagaaagcc cgcgcccgcc
     5641 atgagagccg tggcaagctg tacgtgcgtg accgcatcga ccatttgatt gatgaaggct
     5701 cgccgtttct ggagttttcc gcgctggcgg cgcatcacgt ttacgacagt gaggtacctg
     5761 ccgcaggcgt gatcaccggg attggtcggg tgtctggcgt tgagtgcgtg attgtggcca
     5821 acgacgccac ggtaaaaggc ggcacctatt tcccacttac ggtgaaaaag cacctgcgtg
     5881 cccaggaaat tgcccgcaag caccgcctgc cgtgcatcta cttggtggat tctggcggtg
     5941 ccttcctgcc ccgccaggac gaagtcttcc ccgaccgcga ccacttcggg cgtattttct
     6001 acaaccaggc cacgatgtcc gctgaaggca ttccacagat cgccgtggtg atgggctcct
     6061 gtaccgcagg gggtgcatat gtgcctgcca tggcggatga gtccatcatt gtcaaagagc
     6121 aaggcacgat cttcctgggt ggcccaccgc tggtaaaagc cgccacgggg gagagcatca
     6181 gcgccgagga cttgggcggt gcggatgttc acgccaaagt gagcggtgta gccgaccact
     6241 acgccgaaaa tgacgcccat gcgctgcagc ttgcccgcgc ctgcgtatcg cgtctgaact
     6301 ggcaaaagcg cggccagctg gccatgcagc cgcctaggcc gcccaagctc gacccttcag
     6361 agctttatgg catcgtcggc accgacctga aaaagcccta cgacgtgcgc gaagtgatcg
     6421 gccgcatcgt cgatggctcc gactttgacg agttcaaacg ctactacggt gacacgctgg
     6481 tgaccggctt tgcccatatt cacggctacc cggtggggat cgtggcgaat aacggcgtgc
     6541 tgttttctga gagcgcagta aaaggcgcgc actttattga gctgtgcgcc cagcgcaaaa
     6601 tcccgctggt gttcctgcag aacatcaccg gctttatggt tggctccaag tacgagcatg
     6661 aaggcattgc caagcacggc gccaaactcg tcaccgccgt ggcctgcgcc aacgtgccga
     6721 aatacaccgt gctgattggc ggcagcttcg gcgcgggtaa ctacggtatg tgtgggcgcg
     6781 cttacgaccc caacctgctg tttatgtggc ccaacgcgcg tatttcggtg atgggcggcg
     6841 aacaggcggc gggcgtactt tcccaggtaa aacgcgagca gtacgagcgc gaaggccgag
     6901 aatggagcaa agaggacgaa gaagcgttca aaaagcccac ccgcgaccag tacgagcatc
     6961 agggccaccc ctactacgcc agcgcccgcc tgtgggatga cggcgtgatc gacccgctgc
     7021 aaacccgcga tgtgctgggg ctgtcactgg ccgccgcgat gaatgccgaa gtcaaagaga
     7081 cgcgcttcgg cgtgttccgg atgtaagggg cgaacatcat ggcttactca acattagtca
     7141 tcgaggcggg tatcgctcgc ctaaccttaa accgcccaga ggtgcataac gcctttgacg
     7201 atagcctgat tgccgagcta aacgcgcacc tggaaaagct ccacggcttg gtaagtgcag
     7261 gcgacgtacg ggtggtggtg ctcggctctg aaggcaaaag cttctcggcg ggcgcggacc
     7321 tgaactggat gaagcgcatg gtcgattacg acctggaaga taatctggct gattcccgta
     7381 aacttgcggc gctgatgcac ggcctggata ccctgccctg cccgaccatc tgccgcgtac
     7441 agggggcggc gtttggtggc gcggtgggct tagccgcctg ctgcgatatc gtcgtggcgt
     7501 ccgaaaaagc caagttttgc ctgtcggaag tcaatattgg cctgtcgcct gcggtgatta
     7561 gtccttacgt tcagcgcgcc cttggtcagc gccaaatgcg ccgctacgcg ctgaccgccg
     7621 aagtgatgga tgcgcccacc gcgctcagcc tgggtttggc ccatcaggta gtggagcacg
     7681 atgccttgga taacgcggtg gacagcatga tcgccacgct ggttaaaggc tctccccagg
     7741 cacagcgggc taccaaggca ctattagcca ccgtggccca agctccagat gccgatgcta
     7801 ctcgtgagca cacctgccaa gtgattgcca agctgcgggt gagccaagag ggccaagagg
     7861 gcctcgccag ctttttggac aagcgtcgcc ccgcctggac atctcctgaa gaacacaata
     7921 acgctgcgga gccacgctca tgacgtttac cccgaccaaa ttcgatacgc tcctggtggc
     7981 caaccgcggc gaaatcgcct gccgcgtgat gcgcaccgcc ctccgcatgg ggttaaaaac
     8041 cgtggcggtt tattccgatg ccgacgccac ctcccgccac gtgcgtgaag ccgatgaagc
     8101 cgtgcgcctc ggccctgccg ccgcccggga aagctactta aacgttgacg cggtgattga
     8161 ggccgcccaa cgcaccggca ccggcgcgat tcaccccggc tatggcttcc tgtctgaaaa
     8221 cggcaccttt gttaaagcgc tagagcaagc gggcattact tttgttggcc cgcccgcttc
     8281 cgccattgcc gccatgggcg acaagtctgc cgccaaagcg cgtatggcga atgcgggcgt
     8341 gccgctggtg cccggctacc acggcgacga ccaaggcgat gccctgctgc gttccgaggc
     8401 cgataagatc ggctaccccg tcatgctaaa agccagcgcc ggtggcggcg gtaaaggcat
     8461 gcgcgtggta gagagcggtg aaggcttcca ggccgcgctg gacggctgcc gccgggagtc
     8521 taaagccgcg tttggcgatg accgcatgct gctcgagaag tatttggtac agccccgcca
     8581 tgtggaagta caggtattct gcgaccgtta cggcaacggc gtgtatctgt tcgagcggga
     8641 ctgcagcgtg cagcgccgac atcaaaaagt gattgaagaa gcccccgccc ccggcatgac
     8701 gactgaactg cgcgccgcca tgggcgatgc cgccgttcgc gccgcccagg agattggcta
     8761 cgtgggtgcg ggcacggtgg agtttctgct ggactcttca ccaggtcagg acggcgcttt
     8821 ctatttcatg gagatgaaca cccgcctgca ggtcgagcat cccgttaccg agatgattac
     8881 cggtcaagac ctggtggagt ggcaactaag agtcgctatg ggcgagccgc tgccctgccg
     8941 ccaggacgag ctgaccatta ccggccacag ctttgaagcg cgcatttatg ccgaagatcc
     9001 ggagcaggac ttccttcccg ccaccggcct cctcactcgc ttcgcgctgg acttggaagg
     9061 cgcagggcta ggcgctgatc aagtccgcct agatagcggc gtggagagcg gcgatacggt
     9121 ctcgatgcac tacgacccga tgctcgccaa gctgattgtg catggcgttg accgtgacgc
     9181 tgcgctggca accctcaacc gggcgctggc gtcgctggat gtgcagggcg tggtcaccaa
     9241 ccgcgccttc ttgcagcgct tagccaatca ccctggcttt aagaacgtcg agctggatac
     9301 ccgctttatc gagcgcaacg aagcgaccct gtttgctccg cgtcagtttt ctacagaaga
     9361 ctatgccagc gccgcgctga ttggcttgca tcaattagcc caggagtgcg aaagcgactc
     9421 cccttggggc cgccacgatg gtttccggct caacgccccg cacaccattc gcattgcgct
     9481 gtgtgacccg gcaagcgctc aagccgcgga taatgacagc gcagtggtcg tggtagaggg
     9541 caagcgcgcc accttggata cccagtggca gctcaccatt ggcaacagca cactgactgc
     9601 cagcctacag ccgctggaag gcgatgccgt ggccgtcaca ctcaacggtc accgccgccg
     9661 cttacaggcg tataaagatg gtcatgtagt ggtgatggcc gaacccagcg gtgaaacccg
     9721 cctgttctgg cggcgcatcg acgccatcga ccacggccac cacgaaacgg aatctactct
     9781 caccgcgccg atgaatggca cggtggtggc actgctagtg gaaccgggtg ctcaggttga
     9841 aaaaggcatg ccgctgatgg tgatggaagc catgaagatg gagcacacca tgaccgcccc
     9901 cgccgatggc agcgtagaga ccttccactt ccaggcaggc gatacggtaa gccagggcgc
     9961 tgtgctgctc gactttgccc ccagcgaata ggagccacac atggcactgc ctacgtctat
    10021 caagctattt gaaatggccc cccgcgacgg gctgcagaac gagccgggca ccctggtgcc
    10081 caccgccacc aaaatcgagc tgattgagcg gctggcgaat gcgggcattc gccacattga
    10141 agcggccagc tttgtctcgc ccaaatgggt gccgcaaatg ggcgatgccg ctgaggtgat
    10201 gcgcggtatt cagcgccagc acggcgtggt gtattccgcg ctaacgccta acctcaaagg
    10261 attagaaggc gccctggagg caggcgttga ggaagtcgcg gtattcggtg cggcatcgga
    10321 agcgttctcc cagaagaaca tcaactgctc aattgccgag tcgctggcgc gctttgagcc
    10381 ggtgctttcc cgcgccaacg aggtaggcgt gagggtgcgg ggctacgtct cctgcgtgct
    10441 gggctgccct tacgagggcg acattgcccc ccataaagta gcggatgtcg ccaaagcgct
    10501 gtatgagatg ggctgctatg aagtttccct gggcgacacc attggcgtgg gtacgccgct
    10561 ggccactaag cgaatgatcg aagccactcg ccaacaggtg ccgattgaga aactggccgc
    10621 tcacttccac gacacttacg gcatggcgat tgccaacctg tacgccgtgc tggaagaagg
    10681 cgtgagcgtg atcgatgccg ccacggcagg cctgggtggc tgcccctacg ctaagggcgc
    10741 atcgggcaac gtggccaccg aagacgtgct ctatttattg gaagggctgg gcatcgatac
    10801 cggcatcgac cttcaggtag tgatcggtac cggctactgg atcacgcggc agttgggccg
    10861 ccagcccagc gccaaagtag cgctggccag agggtgcaca cagcgcactc ccggctagta
    10921 cggcccggcc ctaataatta aaaacgcttc acttcccgtt cagacaacaa aaagatttcg
    10981 gagagactca ccatggcatc atctgcaccg ctttccagcg ccctgcccag ctacactagc
    11041 agcaccgccg acaaaccctt gctgggcatg accattggcg ataaattcga ccaaattgcc
    11101 gcccagtatc cggataacga cgcgctgatt gcgctacacc agaatattca ctggagctac
    11161 cgcgagcttc agcaggaagt gaaccgctgc gcccgcgccc tgctcgcgat tggtgtacaa
    11221 aaaggcgacc gcgtgggcat ttgggcaccc aactgcagcg agtggacgtt gacccagttt
    11281 gccaccgcta aaattggcgc aattctcgtg aacatcaacc cgtcttaccg aacccacgag
    11341 ctggagtacg cgctgaacca gtccggcgcg cgctttttag tcaccgccaa ccaattcaaa
    11401 agctccgact acacggcgat gctgttcgag ctggcgccag agctcaacaa ctgcgcggaa
    11461 ggtcaactaa aatcacagaa gctgcccgag cttgagtgcg tgattaattt aagcgccgac
    11521 aagcacagcg gcatgtggcg ctgggcagat ttcatcgccg aagccgacaa ggtgagccaa
    11581 accgacgtgg acgacctaca ggccacgctg cagttcgatg atccgatcaa tatccagtac
    11641 acctctggca ccaccggctt tcccaaaggg gccacgctct ctcaccacaa cattcttaac
    11701 aacggctttt ttgtggccga aagcatgggc tttaccagcg aagaccgctt ggtgattccc
    11761 gtaccgctct accactgctt tggcatggta atgggcaacc tgggctgcgt gacccacggc
    11821 gcggcgatga tctacccaga tgaaggcttc gaccccggta aagtgctgaa agccgttcat
    11881 gagcagaaag ccactgcgtt gtatggtgtt cctaccatgt tcatcgccga gcttgagcac
    11941 ccggatttcg ccagcaccga tttttcgacg ctgcgcaccg gcattatggc gggctccatt
    12001 tgcccggcag agatcatgaa gcaggtcatc aacaagatga acatgaaggg cgtgcaaatc
    12061 gcctacggca tgaccgaaac cagcccggtc tccacgcaaa ccggcgcgaa cgacaccatt
    12121 gaaaagcgcg tttccaccgt gggccgcacc cagccccacc tggagagcaa gattgtcgac
    12181 cccggcaacg gcggtattct accccgtggc gaaatcggcg agctgtgtac ccgtggctac
    12241 agcgtgatgc tgaagtattg gaacaacgac aaagccactg ctgaggccat cgacgagaca
    12301 ggctggatgc acaccggcga cttggccacc atggatgacg agggctacat ccagatcgtc
    12361 ggtcgcatca aagacatggt gattcgcggc ggcgaaaacg tctacccgaa agagatcgaa
    12421 gagttcttgt acgctcaccc ggcgatttcc gaagtacagg tcaccggcgt gccagataaa
    12481 aagtacggcg aagagctgat tgcctgggtg aagctcaaca gcacggcggg cgaaattacc
    12541 ggggaagacc tgcgcgaata ctgcaaaggc aaaatcaccc acttcaagat cccgcgctac
    12601 ttcaagttcg tggatgagtt cccgatgacc gtgaccggca aaattcagaa attcaaaatg
    12661 cgcgaaatct cgattaaaga gctggggctg gaagaccaaa agtaaaaggg atcgaagctg
    12721 ttacaacgat caactgtcga tcagaacaac ccgtagcggc ggccttcgcc agggttgttc
    12781 tgatcctgag acgctagccc caaccgaggc tccccatgcc cacttccctc gcccaccact
    12841 accatcaagc gctgcgcgac caggatatcc ttaaccaact gagctcccac taccccgatg
    12901 gccccacgct gcatcaatta gcaccgctcg accagctgca tattggcggt atcgccgcat
    12961 caaaaaggct cttggatttg ctcgatcaga gcgcccctat ggcgctggat attggcgcag
    13021 ggctgggggg attgatgcgc cagggggccg cattgggttt tcatctcacc ggactggata
    13081 ttacccaccg ctttaacgtg ctgaatcaag ccatcagcga actggcaatg acacagcctc
    13141 ctaacgattc atcagcgggc actctgcgct gtgtgacggg agatgcctgc gcactgccgt
    13201 ttagtgatgc cagcttcgat gctgtgctgt tccaacacag cctgatgaat atgcccgatc
    13261 ctgcacgcgt actggccgag tgccgccgcg tgctgcgccc cggcgggcag ctggtgatgc
    13321 atgaggtggt cagcggccct cactgcgagg cactgcgttt tccggtgccc tgggcagaag
    13381 ggccgacaca ctcgcatttg ctgacgttgg cggcattgac acagcgactg caaacggcgg
    13441 gcttcgatat tcgacactgc gaagactgga gccacaccgc gcttaaatgg cgccagcgcc
    13501 agcgtcaaaa agagcagccc ccgcgtaccg gtgtgctctc cccgcagtgg gtgtttggcg
    13561 aacggtttat gtgcatgggt aaacatttat tggaaaactt ggcgaatggt gcaattaacg
    13621 tggtggaaat cagcgcccgt tgctagtctg ttagggataa cgtcaacaag aaaggacaag
    13681 aggaacgcca atgaaccgct tggcaagcac cctgctcttg agtctgttcg gcacgctcct
    13741 acccctagaa gccaccttgg ccgatgatga cgctcctgct ctctcctatg cagcccccaa
    13801 tagcgaatgg atgcgcctcg ataacggtgt ggtgctggaa ggcagcgacc tgagcagcct
    13861 ggacaccaac accaccggct ttcggctgac cgcgggattc agccccgaac agctgccccg
    13921 gctggatatc ggtgccgaga tcgcctatcg cgaaagtgaa gaagtcccca ttacttccca
    13981 gatgaacccg ctgctcatgg acaccctgag cctgggtggc gccttggtgg caggcgtgcg
    14041 catgggcgcc gtcagcattt atgccaagtc cggcttcacc gagtggcgtg gtgaagcgta
    14101 ccagccccag accgatgatg gcggcacggc gctactgcaa ggcttcggcg ccaccatgac
    14161 catcaaccgg ttgatcagcc gtttcgagta cgagcgtatc gatgcagcca cgctcagcca
    14221 cctcaatatg ctcagcgctt cgctacacct gccgttttaa tcccagtttt cgatgctgcc
    14281 agccgagatg tctcttgact cggcgtttat ccgtgttaat gtactagcgt actagtacat
    14341 taacacggat tacatcgacc gctggtgact cactcatgcc cctctctccg tcacactatc
    14401 agactgagct ggtacgccat ctggtggcca tcgagacccc cgaggccatg gacgctgcgc
    14461 tggcaagcct tctgacccca gcggagtacc aggaaatcag caagcgcctg cagattttca
    14521 agctgctcaa cgaagggatg ccccaccgca agattgccga caccctcggg gtcggtattg
    14581 ccacggtatc caggggctct cgcgcactga accagtcatc ttcatcacgg aacgcccctt
    14641 tatgagcact cacactcagg ccaacacccc tggcccaacg ccgtttacac tgccccgtaa
    14701 accccactac gtcacgctgg cggcagactg cgacttcttc gccctgtttc agaaaatcga
    14761 gcggcgcttc gatacctgct acatgcttga gtcactaggc gaagatagcc acatggcgcg
    14821 ccactcgatc attggtttcg accccgaata tacgctgtac gccaatggcc acacgctgac
    14881 catcgaaaac cgcgacggtc aggccgagca gtacaccagc gagaacccct acgagctgct
    14941 gcgcagcctg attccgcaga acatcatttc ccgcaagtac gccggcggcc tcagcggcta
    15001 tctgggctac gacgccatgc agtacttcga gccttcgctg acgctgaaag ccagcgacga
    15061 cttcgatacg ttccgctttg ggctgtacaa agacggcctg attctcgaca agatgaccgg
    15121 ggaagtcact tacttctatt acgataatag ccgttacgcg tttctgcaga cgctgatcga
    15181 cgccgacgac gagccagcag gcccgctgca cattaccgcg ctgggcgaca ccatgagcaa
    15241 agccgagcat gccgcagcgg tcgccaaggt gaagcaggac attatcgacg gtaaggtttt
    15301 ccagtgcgaa gtgggcttta aaaagcgctt tcgcattcag ggcgacaccc tggcgcttta
    15361 cgaccaactg cgtaccatca acccctcgcc gcagatgtac tacgtgaagt ttggcgaaca
    15421 gaagttgatt ggcgcgagcc ccgagctgct gttccgcctg cgccagggcg agatggagac
    15481 gttcccgctg gcaggcacta ccctgcgcgg ccaaacgccc caggaagata cccagcttgc
    15541 ccgcgcgctg ctcaacgacc ccaaagagat cgccgagcac aatatgattg tggacctgca
    15601 ccgcaacgat attggtcgag tggcgcagtt tgggacggtc aaagtgcgca gcctgatgga
    15661 tatcaagcgc ttcagccacg tacagcacat ttcgagcgag atcgtcggca ttatagccga
    15721 gagcgaagac atgttcaccg cgctggccag caacttcccg gcaggcacgc tcaccggagc
    15781 gcccaaaatc gaggcgatga aaatcatcga cgatctggaa accgatgggc gcggccccta
    15841 cggcggcgcg gtgggccagt tctctttcaa cggcgactgc acctttgcga tcccgatccg
    15901 tacggtgttt gtcaacggcg agcgcgccta cgtacaaacc tgtggcggca acgtgtacga
    15961 cagcaacgcc gaggatgagt acgaagagat tcgccgcaaa ttcgccggca ctcgcaaggc
    16021 cttggccccc tttatggata cggaaacgga gagccccgca tgaaggtgct gatcatcgat
    16081 aactacgact ccttcaccta taacctttac cagtttattg gtgagattct gaccacggag
    16141 aagaatcgcg gcgagctgcc tcattttgag atcatggtga agcgcaataa ccagattgat
    16201 tttaaagcga ttgaagccat ggcgccggat cgcattatta tctcgcctgg cccaggctcg
    16261 ccggatgacc cgcgctactt tggcgtatgt gccgaggtga ttgagaagct gggcaaaacc
    16321 acgccactgc tgggggtttg cttaggcatg caagggattg tgcatgtgtt tggcggcaag
    16381 gtggtcaaag cgccgctgcc aatgcacggt aaaatcagcc ccattaatca caataaccaa
    16441 tcggtattca acggcgtgcc cgaccagctt gaagtgatgc gctaccactc actgattgcc
    16501 gatgcggcga cacttccaga gtgcctagaa gtgaccgcca cagtaggtgc actcaccgcc
    16561 gacaactttg ctgaacgcgg ccgctggcag gcagcgggtg agtttgagct gatgggcgtg
    16621 aagcaccgtg actacccgat tcacggcatt cagtttcacc cggagtcgtt tgccaccgag
    16681 ggcggcaaag agttaattgc taacttccta tttgccccta acgcagcggc ataaccgcga
    16741 cgaaaccgcc taacactgca atattgagca gcaccgtggc ccaataaacg cgtcgaaagc
    16801 tggttttttg ggtcttgtgg cgcagctgct gctgcgcgca ccatgccccc ggccaaccgc
    16861 ctagcagcgc cagccagtgc agcgttttct cactcacccg ctggcgctgt ttaatcgcgg
    16921 cccgcttatc ccacgcatag agaacgtagg taatcacgct ggccgtcgca taccacgcca
    16981 gtaggtaact catataagtt ggcatctctg tcatggagaa ctacttgcgc cgggaaggcg
    17041 gcttaccgga ggcagcttta cccccgctgg ggcgtccgcc ctttatcgcg cccttacgcg
    17101 cgcccggttt gccgctagag tggctcccgg gcctcccctt tcctttagtg gccggtcttc
    17161 ccgctgacac tgctcctttg ccgcctgact taccagcagc ggcccctttt gccttgggat
    17221 ccttgcgggc tttgttaccc gcgccggcac ctgaagaggc ccgttttgct gccgtctttt
    17281 tatcctgcgc gctacttcta ccgccgctgt agttgggtcg ggcgattttt ttcttctcag
    17341 gtgctttctt ctcagatgtt ttcttctcag gcgctacatc tgaggtttcg gtgagggcaa
    17401 caatggtctc gatctctttg ggcgtcaggt cacgccaatc ccccagcgcc agccctttca
    17461 gcgagacgtt catgatgcgc gtacgtacca gttgcgtcac ttcgtagcca aagtattcgc
    17521 acatacggcg aatttggcgg ttgagcccct gcactagcgt gatattgaac acaaaggtgg
    17581 actctttaac cacctgacac tttttggtca tctgcccaag gatcggcacg ccgccctgta
    17641 taccggcaat aaactcgttg gtgatcggtt tatcgaccgt caccacgtac tctttttcgt
    17701 ggttgttgtt ggcgcgcagg attttgttga ccaagtcgcc gttgttggtg agaaagatca
    17761 acccctggga gtctttatct aagcgcccaa tggggaaaat acgcgtgccg tgcttcacaa
    17821 actcaacgat attgtctttt tctgccgact ccgtggtgct gacaatcccc accggtttgt
    17881 tgagcgcgat cagtactaaa tcctcctctt cctgcggctc aatctcctgg ccgttgacct
    17941 ttacccgatc ccccgcgacc acttggtcac cagtggttgc ccggcggccg ttgatccaca
    18001 cattgccctg ctcgacaaag cggtccgcct cccggcggga gcagaggccg ctttcgctga
    18061 tgtatttatt gatacgggta gattttcgta acgacataaa tcgccatata gcctaaataa
    18121 acgttaaaaa gaggagccgg gctgcttgag gaactcgacc tcttccggag tcgaggctct
    18181 gcccaagacc gcattgcgat gcgggtagcg cccaaagcga tcgataatct gttggtcgat
    18241 ttgggcatct ttcttaaacc actgggctgg cgacaactcc tgaaaccaga atgccagcac
    18301 ggcctgagcg tctgtggtca tgtttctgcc tccaacactg gacataaaga aaagcgccgc
    18361 cacccatcgg tagcggcgct ggtgggctgt cttcagctta gccggtgtta cgcaggccag
    18421 ccgcaatacc cgccatggtg accattaacg cgcgggagag atctgggcta atcgccccat
    18481 cagcatcccg gttacgctgc aaaagctcgg cttgcaggcc atgcagcggg tcgatgtagg
    18541 ggttgcgcac gtcaatcgcc tgacgaatca gtggcgtgtt ctccagcagt ttctcctgct
    18601 gcaggatatc taacaccaca tcttccagac gctcgaagcg ctcacggagt tttttgccca
    18661 gcgcttttag cgacggctcg tccaccaagc ggtgctcgta gtaggcggca atcgccacgt
    18721 ctgctttggc tagcagcatc tctaacatat ccaggtaggt gccaaagaag ggccactggg
    18781 tgcgcatttc ttgcagcact tcacggccgc cgggctgctc cagacggcgg gagaaggctt
    18841 cgccactgcc aagccaagcg ggcagcatca ggcggatctg cgtccaggca aaaatccagg
    18901 ggatcgccct cagggtttcc acaccaccat cctggcgacg cttggtcggc cgcgagccta
    18961 gcggcagcct acccagcgcg ccctccggcg tcaccgcacg gaaatagggg acgaagtcgg
    19021 gatcttcccg tacaacaccc acgtaagccg catgggccac cttggccagt tgatccatct
    19081 cttcgcgcca gtggggttcc ggcgcgggcg gtggcaatag cgtggcttcc agcaccgcac
    19141 aggcgtagat ctccatggaa cgcagcgcga tatccggctg gccgaactta aagcgaatca
    19201 tctcgccctg ctcggtcacc cgcaggctgc cgttcacgga gccaggcggc tgagacagaa
    19261 tcgccgcgtg agccgggccg ccaccacggc caacggtgcc gccacggccg tggaacagcg
    19321 ttaggtccac accatgtttc tcacacacgt tcaccagcgc ttcctgggcg cggtactgtg
    19381 cccaagcggc ggcgagctga ccggcatctt tggcggagtc ggagtagccg atcatcactt
    19441 cttggcggtc tttcgtcagg gcgcggtagc ccggcagcgc cagcagctga tcaaccacat
    19501 cccccgcgtg gtccaggtcg ttgagggtct cgaacagcgg cgcgatgggc agcgttactt
    19561 gcccacccac ttccttcatc aacagtgcca cggtgagcac atcagagggc tcggcggcca
    19621 tggagataat gtaagtaccc agcgcttccg cgtgctcctg ggcgatcacc ttgaaggtat
    19681 cgatgacttc ccgggactct gccgaacact cccagcggcg gggaatcagc gggcggcgag
    19741 actcaagctc cgccagcaaa aactcctgac gctgggtttc gctccactcc tggtaatggc
    19801 ctagccccag ggagctggtg agttcttcca ttacttgggc gtggcggctg gcttcctggc
    19861 gaaggtcgag cttggtcagc gtgacgccga acacggccac gcggcgcagg gtatccagca
    19921 gcgcaccgtt ggcaatggta tccagcccca cgtcgcacag cgagcggtag caggccagca
    19981 gcggcgcgta aatttggtcg cgggtttcaa taatcggccc gccatcgtag ttgcggccat
    20041 ccagctgcgc ttttgcccag tcgcgggtgg cttccatttt ggttagtaac cgtttgagca
    20101 gctcccggta gggttccgcc acatcgccca cttcggcttt tagggcgctg ttggctttcc
    20161 acatggagag ctcggttttg agctgttcta aatcgcgcag atagagatcc gctgccatcc
    20221 agcggcctag cagcagcact tcctgggtga ctttggcggt gacattcggg ttgccgtcgc
    20281 ggtcgccacc catccaggag gcgtagcgaa tcggcgcggc atccagcggc aggcgctcgc
    20341 ccgcagtgtc cagcagcagg ttatccaggt cgcggtggaa atccggcacc gcctgccaca
    20401 gcgagttctc gatcaccgca aagccccact tcgcctcatc caccggcgtt gggcgttcgt
    20461 gacgaatctc gtcggtatgc cacgcctgac taatcagctc ttccaagcgg ccttgggcgc
    20521 gggcgccgcg ttcggggtaa tcttccgaac tctcaatcgc ggtcaagcac tcatcaatgg
    20581 cgtcgtactt ctgaatcagc gtgcggcgga taacttcggt ggggtgggcg gtcaatacca
    20641 gctcgacgcg catattggct agagtttcca ccagtttacg gggcgagtta ccgacctgct
    20701 gagcacgtgc taacaactct cctagcgctg gctgcgagcc gggtttgtag tcctcgaccc
    20761 ggcgaaaccg cgcccgatag tgctgctcgg caatgttagc caggttcaaa aactggttaa
    20821 aggcgcgggt aacgggtaag aggtcgcgct cgggaagctg gcgcaggtac tctatcaact
    20881 ggcgctgctg cagtgagtcg ccctggcgac cccgcttggc atgggcacga atggtttcga
    20941 ttttatcgac aaacgactgg cctaaatcgt cggcaatggt tcttcccagg ctatcgccta
    21001 ggatacgcac gttgtcgcgc agggattcgt gtaaatcatg actcatgggc gtggcctcct
    21061 tgcggggtcg cgttgatgat tttgaaatta gcgttgttct tgggctttag cggcttgcca
    21121 gtggccttcc atttcgtcca gcgaggcctc gcttagcggg cgctctgcct cggcaagcgc
    21181 gcgttccaca tagcgaaagc ggcgctcaaa ttttgtattg gtgttacgca ggcactgttc
    21241 ggggtcggcc ccgagggtgc gggctaaatt ggtgacggca aacagcaggt cgccgacctc
    21301 ctcctgggcg tgctgacgat cccccgccgc cagcgcctct tcgacctcct ccagttcctc
    21361 gcgaattttg gccagtacgc cctcggcatt cgaccaatca aagcctacgc gggcggcccg
    21421 cttcgagagc ttggcggcgc ggcttaacgc aggcagcgtt cggggcacat cgtccagcac
    21481 cgaaggaggt tgcgtagcac gcttggcgcg ttcgtcggct ttgagcgctt cccagcggct
    21541 attcacctgc tgggtcttta cttcatcggc actcacgccg gtcgggcgac gggacgccag
    21601 cgttccgtct gggaacacat ggggatgacg gcgcagcatc ttggcggtca gcgtatcgac
    21661 gatatcgtga aaatcgaagc gctgctcttc tgcgccaaat tgggcgtaat agaccacttg
    21721 aaaaagcagg tcgccgagct cgccgggcag ttcatcgaag gcgcgacgct cgatggcgtc
    21781 ggccacttcg taagcctctt ccagggtgtg gggcacgatg ctgtcccaat cctgctggat
    21841 atcccacggg cagccctgct cccggtcgcg caatacggcc attagggtga gcaaatcatc
    21901 cagggtgtgg cgcatcaggc ccctcctttg cgggcacttt tttcggggtc ggcattacgc
    21961 aggcggcgca cttcggtcac gttgggtagc tgctggatgc gcgagaacag cctgccgaga
    22021 gattccagac cgtccacttc cagggtaatc ctcaggcggg caatgccttc gtcagtgtcg
    22081 gttaaggtat tcaccgccag cacgttgacc ttctcgttgc ccagcaagcc cgtcacatcg
    22141 cgtagcaggc ccgagcggtc ccaggcttga atctcgatgg tcaccgggta acgggtgtgg
    22201 gcccgctcgc cccactccac ctcgataatg cgctggggct cttccatgcg caattggaga
    22261 atgttgggac agtcctggcg atgaacggtc acgccgcgcc cttgggtaat aaagccgaca
    22321 atcggctcgc cgggtaccgg gcggcagcag ttggccatgc tggttttcag gttgcccacg
    22381 cccagcacgg tgatgtcgct ttgggtcgcc ttgctgggct ggcggcgggg tttggctagc
    22441 aggcgatcga gctgctcttg gtcgtcggtt tcaccaaaca gttgctgggc ctggtgcagc
    22501 acttgaccaa ttcgcaggtc gcccgccccc agcgccgcgt acatatcgtc ggcgttttgg
    22561 tagttgacgg ctttggcgag cttagcaagg tccagccctt ccacatccag gcggcgcatt
    22621 tcacgctcaa acagcgtgcg cccttcgtcc aggttctggt cgcgggcctg atgcttaaac
    22681 cacgcctgaa tttttgcccg ggcgc
//
