LOCUS       c00453_3300026..        3880 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300026534.a:Ga0256841_1018846.
ACCESSION   c00453_3300026..
VERSION     c00453_3300026..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 13:02:17
            Original ID  :: 3300026534.a:Ga0256841_1018846
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3880
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..3879)
                     /NRPS_PKS="Domain: AMP-binding (95-532). E-value: 5.4e-109.
                     Score: 356.2. Matches aSDomain:
                     nrpspksdomains_ctg453_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (671-738). E-value: 1.7e-26. Score:
                     84.0. Matches aSDomain: nrpspksdomains_ctg453_1_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (759-1059). E-value:
                     4.4e-123. Score: 401.8. Matches aSDomain:
                     nrpspksdomains_ctg453_1_Condensation_LCL.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     503.5; E-value: 1e-152)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg453_1"
                     /sec_met_domain="Condensation (E-value: 9.4e-88, bitscore:
                     280.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.1e-120, bitscore:
                     388.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.1e-19, bitscore:
                     55.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="DVDPGTATFDLTLSLAEEADGMDASMEFNTDLFDRATVERMLGHF
                     ENLLRAIVADPAQPVDQLELLDPAEKRQILVEWNDTARNFPLDRCVHQLIQEQVERTPH
                     ALAVVAGDEQLTYAELNARANQLAHFLRQQGVGPEERVAIALERSVHLIVAVLGVLKAG
                     GAYLPLDPTHPAERLNFMLQDASPRILLTQESLADQLPIAHLQAPIPVVKLDADWPAIA
                     QQPTENPGIPVQPDNLVYTIYTSGSTGQAKGVLVEHRNLVNMFFAWKEAYGLEQVSSHL
                     QMANFAFDVFSGDLVRALCSGGKLVLAPREWLLEPAKLYELMRREQVECAEFVPPVLRQ
                     LIQHLEQTGQRLDFMRVLACGSDSWYVEEYRSFLAYCGPETRLINSFGLTEATIDSTYF
                     ESSQLELSEGQIVPIGRPFANVQTFILDRRRQPVPIGVPGELYIGGAGVARGYLNRPEL
                     TAERFVPVEELEFVGQGVTSEGVRSKELEDGATSDSLLMTPSSSRLYRTGDLARYLPDG
                     NIEFLGRADHQIKIRGYRVEPGEIEAVLTRFPQVQEAVVLARTNPAGQKQLVAYFVPTD
                     GAAEEGDPTLHASRSTDEATEAGPETNLTPSTSLIPDLRAFLKEHLPEYMVPAYLVPLE
                     RIPLTPNGKLDRRNLPEPDWSQRQLEGAVVPPRTATEEVLAGIWSQVLGVAELSVFDNF
                     FELGGHSLLATQVISRIREAFQVELPLRTLFMAPTIAEQAEQVEIALRNEAGTQAPPIE
                     PVPRDGPMPVSFAQQRLWFLDQLEPDSPFYNIPESVRLQGRLDVSTLEKAFNEIIRRHE
                     ILRTTIDTVDGRPVQRIHPEFTLELPVTDLTHLSQEEQEELIPRLAAEEAQKPFKLDRL
                     PLLRARLLRLGPEDHVILLTIHHIIGDDWSTGVLIQEIAVLYEAFLAGRPSPLPELPIQ
                     YADFAHWQRHWLQGDVLEQHIRYWKEQLADAPPLLELPTDRPRPPVQTFRGDYEKFVLP
                     PKLSQAILELSRQEGATLFMTLLAAFQVLLHRYSGQEDIVVGSPIANRNRAEIENLIGF
                     FVNTLVLRTDLSGEPSFRELVKRVREVALGAYAHQDLPFEMVVEAVQPERNLSHSPLFQ
                     VMFVIQNTPVQAQKLPELLLAPVEAHSGTAKFDLTLFVLEEEGQLAGAFEYNTDLFDRE
                     TIQRMVGHFRTLLEAITADPDQPITRLELLTLEEKRRILVEWNDTAHPFPQDRCVHELI
                     QEQVERTPHALALVAGDEQLTYAELNARANQLAHFLRQQGIGPDDLVALSLTRSANLLV
                     AILAVLKAG"
     protocluster    1..3880
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:3879](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(1..3879)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..3880
                     /SMILES="NC(CCCN)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3880
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS_motif       complement(547..663)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg453_1_0011"
                     /evalue="9.10E-27"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg453_1"
                     /protein_end="1111"
                     /protein_start="1072"
                     /score="85.6"
                     /tool="antismash"
                     /translation="REVALGAYAHQDLPFEMVVEAVQPERNLSHSPLFQVMFVI"
     aSDomain        complement(703..1602)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg453_1_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="4.40E-123"
                     /label="ctg453_1_Condensation_LCL.1"
                     /locus_tag="ctg453_1"
                     /protein_end="1059"
                     /protein_start="759"
                     /score="401.8"
                     /tool="antismash"
                     /translation="PMPVSFAQQRLWFLDQLEPDSPFYNIPESVRLQGRLDVSTLEKAF
                     NEIIRRHEILRTTIDTVDGRPVQRIHPEFTLELPVTDLTHLSQEEQEELIPRLAAEEAQ
                     KPFKLDRLPLLRARLLRLGPEDHVILLTIHHIIGDDWSTGVLIQEIAVLYEAFLAGRPS
                     PLPELPIQYADFAHWQRHWLQGDVLEQHIRYWKEQLADAPPLLELPTDRPRPPVQTFRG
                     DYEKFVLPPKLSQAILELSRQEGATLFMTLLAAFQVLLHRYSGQEDIVVGSPIANRNRA
                     EIENLIGFFVNTLVLRTDLS"
     aSModule        703..1602
                     /domains="nrpspksdomains_ctg453_1_Condensation_LCL.1"
                     /incomplete
                     /locus_tags="ctg453_1"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(712..801)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg453_1_0010"
                     /evalue="5.10E-19"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg453_1"
                     /protein_end="1056"
                     /protein_start="1026"
                     /score="60.6"
                     /tool="antismash"
                     /translation="DIVVGSPIANRNRAEIENLIGFFVNTLVLRT"
     CDS_motif       complement(1054..1092)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg453_1_0009"
                     /evalue="3.40E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg453_1"
                     /protein_end="942"
                     /protein_start="929"
                     /score="19.5"
                     /tool="antismash"
                     /translation="QYADFAHWQRHWLQ"
     CDS_motif       complement(1141..1206)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg453_1_0008"
                     /evalue="1.50E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg453_1"
                     /protein_end="913"
                     /protein_start="891"
                     /score="30.3"
                     /tool="antismash"
                     /translation="IHHIIGDDWSTGVLIQEIAVLYE"
     CDS_motif       complement(1426..1539)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg453_1_0007"
                     /evalue="5.20E-19"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg453_1"
                     /protein_end="818"
                     /protein_start="780"
                     /score="60.6"
                     /tool="antismash"
                     /translation="PFYNIPESVRLQGRLDVSTLEKAFNEIIRRHEILRTTID"
     CDS_motif       complement(1558..1590)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg453_1_0006"
                     /evalue="2.20E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="ctg453_1"
                     /protein_end="774"
                     /protein_start="763"
                     /score="10.5"
                     /tool="antismash"
                     /translation="SFAQQRLWFLDQ"
     aSDomain        complement(1666..1866)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg453_1_PCP.1"
                     /evalue="1.70E-26"
                     /label="ctg453_1_PCP.1"
                     /locus_tag="ctg453_1"
                     /protein_end="738"
                     /protein_start="671"
                     /score="84.0"
                     /tool="antismash"
                     /translation="EEVLAGIWSQVLGVAELSVFDNFFELGGHSLLATQVISRIREAFQ
                     VELPLRTLFMAPTIAEQAEQVEI"
     aSModule        1666..3594
                     /complete
                     /domains="nrpspksdomains_ctg453_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg453_1_PCP.1"
                     /locus_tags="ctg453_1"
                     /monomer_pairings="orn -> orn"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(2161..2217)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg453_1_0005"
                     /evalue="4.80E+00"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg453_1"
                     /protein_end="573"
                     /protein_start="554"
                     /score="-0.1"
                     /tool="antismash"
                     /translation="VVLARTNPAGQKQLVAYFVP"
     CDS_motif       complement(2254..2319)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg453_1_0004"
                     /evalue="2.20E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg453_1"
                     /protein_end="542"
                     /protein_start="520"
                     /score="38.8"
                     /tool="antismash"
                     /translation="FLGRADHQIKIRGYRVEPGEIEA"
     aSDomain        complement(2284..3594)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg453_1_AMP-binding.1"
                     /evalue="5.40E-109"
                     /label="ctg453_1_AMP-binding.1"
                     /locus_tag="ctg453_1"
                     /protein_end="532"
                     /protein_start="95"
                     /score="356.2"
                     /specificity="consensus: orn"
                     /tool="antismash"
                     /translation="QEQVERTPHALAVVAGDEQLTYAELNARANQLAHFLRQQGVGPEE
                     RVAIALERSVHLIVAVLGVLKAGGAYLPLDPTHPAERLNFMLQDASPRILLTQESLADQ
                     LPIAHLQAPIPVVKLDADWPAIAQQPTENPGIPVQPDNLVYTIYTSGSTGQAKGVLVEH
                     RNLVNMFFAWKEAYGLEQVSSHLQMANFAFDVFSGDLVRALCSGGKLVLAPREWLLEPA
                     KLYELMRREQVECAEFVPPVLRQLIQHLEQTGQRLDFMRVLACGSDSWYVEEYRSFLAY
                     CGPETRLINSFGLTEATIDSTYFESSQLELSEGQIVPIGRPFANVQTFILDRRRQPVPI
                     GVPGELYIGGAGVARGYLNRPELTAERFVPVEELEFVGQGVTSEGVRSKELEDGATSDS
                     LLMTPSSSRLYRTGDLARYLPDGNIEFLGRADHQIKIRG"
     misc_feature    complement(2395..2397)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS_motif       complement(2491..2580)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg453_1_0003"
                     /evalue="3.00E-20"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg453_1"
                     /protein_end="463"
                     /protein_start="433"
                     /score="64.2"
                     /tool="antismash"
                     /translation="PIGVPGELYIGGAGVARGYLNRPELTAERFV"
     CDS_motif       complement(3106..3162)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg453_1_0002"
                     /evalue="4.70E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg453_1"
                     /protein_end="258"
                     /protein_start="239"
                     /score="25.3"
                     /tool="antismash"
                     /translation="YTIYTSGSTGQAKGVLVEHR"
     CDS_motif       complement(3370..3411)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg453_1_0001"
                     /evalue="1.30E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg453_1"
                     /protein_end="170"
                     /protein_start="156"
                     /score="18.2"
                     /tool="antismash"
                     /translation="LGVLKAGGAYLPLDP"
ORIGIN
        1 gccggccttg aggacggcca ggatggccac caggaggttg gcggaacggg tcagggagag
       61 ggccaccagg tcgtctgggc cgatgccctg ctggcggagg aagtgggcca gctggttggc
      121 ccgggcgttg agctccgcgt aggtgagctg ttcgtcgccg gccaccaggg cgagggcgtg
      181 gggtgtgcgt tccacctgtt cctggatgag ctcatgcacg cagcggtcct gggggaaggg
      241 gtgggcggtg tcgttccact ccaccaggat gcgccgcttc tcctccaggg tgaggagctc
      301 cagccgggtg atgggctggt ccgggtcggc tgtgatggcc tccagcaggg tgcggaagtg
      361 gccgaccatg cgctggatgg tctctcggtc gaagaggtcg gtgttgtact cgaaggcccc
      421 ggccagctgc ccttcctcct ccaggacgaa gagggtgagg tcgaacttgg ccgtgccgct
      481 gtgggcctcc accggggcca gcagcagctc cggcagcttc tgcgcctgga ccggagtgtt
      541 ctggatcacg aacatgacct ggaagagggg ggagtggctc aggtttcgct ccggttgcac
      601 cgcctccacc accatctcga aggggaggtc ctggtgggcg taggcgccca gggccacctc
      661 ccgcacccgc ttgaccagct cccggaagga gggctccccg gagaggtccg tgcgcaggac
      721 cagggtgttg acgaagaagc cgatgaggtt ctcgatctca gcccggttgc ggttggcgat
      781 gggcgagccc accacgatgt cctcctggcc ggagtagcgg tggaggagga cctggaaggc
      841 ggccaggagg gtcatgaaga gggtggcccc ttcctgccgg ctcagctcca ggatggcctg
      901 ggagagcttc ggcggcagga cgaacttctc gtagtccccc cggaaggtct gcaccggcgg
      961 ccggggacgg tccgtgggca gctccaggag gggcggcgcg tcggccagct gctccttcca
     1021 gtagcggatg tgctgctcca gcacgtcgcc ctggagccag tgacgctgcc agtgggcgaa
     1081 gtcggcgtac tggatgggca gctcgggcag gggcgagggc cggccagcca ggaaggcctc
     1141 gtagaggacg gcgatctcct ggatgagcac tccggtggac cagtcgtccc cgatgatgtg
     1201 gtggatggtc aggaggatca cgtggtcctc cgggcccagg cgcaggaggc gggctcggag
     1261 caggggcagc cggtccagct tgaagggctt ctgggcttcc tccgcggcca ggcgggggat
     1321 gagctcctcc tgctcctcct gggagaggtg ggtcaggtcg gtgacgggca gctccagggt
     1381 gaactcgggg tggatgcgct ggacgggccg gccgtccact gtgtcgatgg tggtgcgcag
     1441 gatctcgtgg cggcggatga tctcgttgaa agccttctcc agggtggaca cgtccagtcg
     1501 gccctggagg cgcaccgact cggggatgtt gtagaagggg ctgtccggct ccagctggtc
     1561 caggaaccag agccgctgct gggcgaagga gacgggcatg gggccgtccc gggggacggg
     1621 ctcgatgggg ggtgcctggg tgcccgcctc gttgcgcagg gcgatctcca cctgctcggc
     1681 ctgctccgcg atggtggggg ccatgaagag ggtgcgcagg ggcagctcca cctggaaggc
     1741 ctctcggatg cgggagatca cctgggtggc caggagggaa tgcccgccca gttcaaagaa
     1801 attgtcgaag acgctcagct ccgccacccc caggacctgg ctccagatgc cggccagcac
     1861 ctcttccgtg gccgtgcgag gcggcaccac cgccccctcc agttgccgct ggctccagtc
     1921 cggctccggc aggttgcgcc ggtccagctt gccgttgggg gtgaggggga tgcgctccag
     1981 gggcacgagg taggccggga ccatgtactc gggcaggtgc tccttgagga aggcgcgcag
     2041 gtcggggatg agtgaggtgg agggagtcag gttggtctca gggccggcct cggtcgcctc
     2101 gtccgtggaa cgtgaagcgt gaagcgtggg gtcgccctct tctgccgccc cgtccgtggg
     2161 cacgaagtag gccaccagct gcttctgccc cgcggggttc gtccgggcca ggaccaccgc
     2221 ctcctggacc tgggggaaac gggtcaggac ggcctcgatc tccccgggct ccacccgata
     2281 gccccggatc ttgatctggt ggtccgcccg gcccaggaac tcgatgttgc cgtcgggcag
     2341 gtagcgggcc aggtcgccgg tgcggtagag gcgtgaggag gaaggagtca tgagtaagga
     2401 gtcggacgtg gcgccatctt ccaactcctt gctccttact ccttcgctcg tcacgccttg
     2461 cccgacaaat tctagctcct ccaccggcac aaaccgctcc gccgtcagct ccggccggtt
     2521 caggtagccc cgggccacgc ccgcgccgcc gatgtagagc tcgccgggga cgccgatggg
     2581 cacaggctgg cggcgcctgt ccaggatgaa ggtctggacg ttggcgaagg gacggccgat
     2641 gggcacgatc tggccctcgg acagctccag ctgactgctc tcgaaatagg tgctgtcgat
     2701 ggtggcctcg gtcaggccga aggagttgat gagccgggtc tccggcccac agtaggccag
     2761 gaaggagcgg tactcctcca cgtaccagct gtccgagccg caggccagca cccgcatgaa
     2821 gtccagccgc tggccggtct gctccaggtg ctggatcagc tggcgcagga ccggcggcac
     2881 gaactccgcg cactccacct gctcccggcg catgagctcg tagagcttgg ccggctccag
     2941 cagccactcc cgaggggcca ggaccagctt cccgccggag cagagggccc ggaccaggtc
     3001 cccggagaag acgtcgaagg cgaagttggc catctgcagg tgactgctca cctgctccag
     3061 cccgtaggcc tccttccagg cgaagaacat gttcaccagg ttgcggtgct ccaccaggac
     3121 gcccttggcc tggccggtgg agccagaggt gtagatggtg tagaccaggt tgtctggctg
     3181 cacagggatg cccgggttct ctgtgggctg ctgggcgatg gcgggccagt cggcgtccag
     3241 cttcaccacg gggatgggag cctggagatg ggcgatgggg agctggtcgg ccaggctctc
     3301 ctgggtgagg aggatccggg ggctggcgtc ctggagcatg aagttcaggc gttccgccgg
     3361 atgggttgga tccagaggca ggtaggcgcc tccggccttg agcacgccca ggacggccac
     3421 gatcaggtgc actgaacgct ccagggcgat ggccacccgc tcctcgggcc ccacgccctg
     3481 ctggcggagg aagtgggcca gctggttggc ccgggcgttg agctccgcgt aggtgagctg
     3541 ttcgtcgccg gccaccacgg cgagggcgtg gggcgtgcgc tccacctgct cctggatgag
     3601 ctggtgcacg cagcggtcca gggggaagtt ccgggccgtg tcgttccact ccaccagaat
     3661 ctgacgcttc tccgccgggt ccaggagctc gagctggtcc acaggctggg ctggatcggc
     3721 cacgatggcc cggagcaggt tctcgaagtg gcccagcatg cgctccaccg tggcccggtc
     3781 gaagaggtcg gtgttgaact ccatggaggc gtccatgccg tccgcctcct cggccagaga
     3841 gagggtgagg tcgaaggtgg ccgtgcccgg gtccacgtcg
//
