LOCUS       c00495_3300026..       10977 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300026534.a:Ga0256841_1003906.
ACCESSION   c00495_3300026..
VERSION     c00495_3300026..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 13:02:17
            Original ID  :: 3300026534.a:Ga0256841_1003906
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10977
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10977
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6443:7484](+)"
                     /cutoff="20000"
                     /detection_rule="(LipM or LipV or LipU or ToyB or TunD or
                     pur6 or pur10 or nikJ or nikO or truD)"
                     /neighbourhood="10000"
                     /product="nucleoside"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6444..7484
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(LipM or LipV or LipU or ToyB or TunD or
                     pur6 or pur10 or nikJ or nikO or truD)"
                     /neighbourhood="10000"
                     /product="nucleoside"
                     /protocluster_number="1"
     cand_cluster    1..10977
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(LipM or LipV or LipU or ToyB or TunD or
                     pur6 or pur10 or nikJ or nikO or truD)"
                     /kind="single"
                     /product="nucleoside"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10977
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="nucleoside"
                     /region_number="1"
                     /rules="(LipM or LipV or LipU or ToyB or TunD or pur6 or
                     pur10 or nikJ or nikO or truD)"
                     /tool="antismash"
     CDS             complement(2..238)
                     /locus_tag="ctg495_1"
                     /transl_table=11
                     /translation="MAAKPVPERVQAIRLGPPLWRDGLFWLALALTLFAVAPFLLPGYF
                     WGANDARHHVYFLFEFDRVVQDGIWWPRWSPDFA"
     CDS             complement(228..1817)
                     /locus_tag="ctg495_2"
                     /transl_table=11
                     /translation="MNTIDTRPSSRLGLWTLLLLGVFAWAPTTYPGYWQALEGFVPVLN
                     AANPGPLADIATEPDLWRGVGGAAFLIARPLILFLGLAPVTAVRLTFALAFILASLGTY
                     VWLYPRLGDRGAALAGLLYALFPPFLATVYVRGSLGDALILALLPVALAGFTLYAGTRF
                     PGAAGVAVIATLWMWRTQAGLALLATLILLAYVLWVERDRLGGLVVLVTGLAGFLALLP
                     LWDQRAPASVPFQEHFLHVFQLLGNGWQVAPSQPGWQDGYPFQLGFPAIAFALILAWIL
                     WQNGRDPDWSGPLPPGGDPALVRLLGFGGLVVALSVLLSLAISEPIWRLTRGQRLLTYP
                     WQVLIFTAPFLALMAGSLPRLRPRLRCAGYWSGLLLLVLLSSYTYLAPNFVNYRPPARP
                     AAILGPHNDILLLEAKLTEESQPPQARLDVVWQPLRPIGFDYNVFFQALQPDPQSGQLQ
                     VVAQLDIQPLPDRPATTWQVGQVITATYRLELPADPAQADLRYYFGLYDWRDGSRLPVD
                     GGADDKVVLYGR"
     CDS             complement(1975..2442)
                     /locus_tag="ctg495_3"
                     /transl_table=11
                     /translation="MGVLDPIKKIAADFILERPVRGKSFAQLADKLALSGQILEDRIRR
                     ARDTERNRQILSHIIGIERWGQSRLRVFLGEPLALDEYDGYRPPQDAGWDELGQAFQAT
                     RRQTLALIQELASRDPGATTRVPHNQFGPLTARGWIRYLDFHANAESKKFR"
     CDS             complement(2510..3094)
                     /locus_tag="ctg495_4"
                     /transl_table=11
                     /translation="MPETLRLFVSATADLEPERAVIGRTLAELPVQIRAQIQRSPLSGI
                     AYADLFERVARCDRFYFLLGQDITAPAGAEWELAWRLERSVLPLRKVGPRTPAAQAFLS
                     WAPVQWIPFRSQAELARIVQLDLIDLLLHPANRYGLSLPELELLALRRRQIQEAQAEAG
                     DEPGGAEGGGVLLDQGRQEPLEGVEVGNVQG"
     CDS             complement(3190..3978)
                     /NRPS_PKS="Domain: Thioesterase (26-129). E-value: 5.3e-10.
                     Score: 31.8. Matches aSDomain:
                     nrpspksdomains_ctg495_5_Thioesterase.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036:alpha/beta hydrolase fold protein (Score: 100.7;
                     E-value: 2e-30)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg495_5"
                     /sec_met_domain="Abhydrolase_6 (E-value: 8.7e-29, bitscore:
                     91.3, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 1e-22, bitscore: 70.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTVDLHGETIFYGFSHTPGEGPPHPPLLLVHGSGGNHLHWPPQL
                     RRLPGGPVYALDMPGHGRSSGRPRPSIAEYREVVRAFAQALDLPPFVLAGHSMGGAIAL
                     DFALNYPERLRGMGLVGTGARLRVAPAILEGLLRDFQATTELITDWALAPSVDPKMRAT
                     VLARMRETPASVIHNDFAACDAFDVMGKLEQIHTPALIVCGAEDRLTPPKYSHYLHQHL
                     PDSRLVLAPDAGHMVMLEQPQAVTQAFQRFLDELAAQPRG"
     aSDomain        complement(3592..3900)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg495_5_Thioesterase.1"
                     /evalue="5.30E-10"
                     /label="ctg495_5_Thioesterase.1"
                     /locus_tag="ctg495_5"
                     /protein_end="129"
                     /protein_start="26"
                     /score="31.8"
                     /tool="antismash"
                     /translation="PLLLVHGSGGNHLHWPPQLRRLPGGPVYALDMPGHGRSSGRPRPS
                     IAEYREVVRAFAQALDLPPFVLAGHSMGGAIALDFALNYPERLRGMGLVGTGARLRVAP
                     "
     aSModule        3592..3900
                     /domains="nrpspksdomains_ctg495_5_Thioesterase.1"
                     /final_module
                     /incomplete
                     /locus_tags="ctg495_5"
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       complement(3658..3711)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg495_5_0001"
                     /evalue="2.60E-06"
                     /label="NRPS-te1"
                     /locus_tag="ctg495_5"
                     /protein_end="107"
                     /protein_start="89"
                     /score="19.9"
                     /tool="antismash"
                     /translation="PFVLAGHSMGGAIALDFAL"
     CDS             complement(4060..5049)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     273.3; E-value: 4.8e-83)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg495_6"
                     /sec_met_domain="RmlD_sub_bind (E-value: 2.5e-13, bitscore:
                     39.4, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTALITGVTGQDGSYLADFLLEKGYHVVGMVRRTSTINFDRIKH
                     IQGRIEIVQGDLLDQMSLISILQEYRPQEVYNLAAQSFVPTSFTQPVLTGEFTALGVTR
                     ILDAIRIVDPSIRFYQASSSEMFGKVREVPQSEKTPFHPRSPYGVAKVYGHWITVNYRE
                     SYDIFACSGILFNHESPRRGLEFVTHKITHAVASIKLGLAKELRLGNLDARRDWGYAPD
                     YVRAMWLMLQQDEPEDYVIATGETHSVREFVEEAFSYVGLDWQEFVVQDPRFYRPAEVD
                     LLVGDPSKAGEKLGWEPAVDFRQLVRIMVDADLEALRREQKALKAQQS"
     CDS             complement(5155..6117)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     258.2; E-value: 1.9e-78)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg495_7"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 2.3e-08,
                     bitscore: 23.1, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 7.6e-12, bitscore:
                     34.5, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRVLVTGIAGFAGSHLADFLLDETDAEVHGILHRHQWRIRHRLEQ
                     LHLHRGDLRNPLWVSQVVQAVQPDRTFHLAAWSDVGGSWRQPWNAYELNILAQLNLLEA
                     LQRTAPEQPVLVVTSNEVYGLVRPEDLPVDEETPFRPNSPYGVSKIAQDMMGLQYWNSH
                     RLPTVRARSFNHIGPRQSDDFVASAFARQIAAIEAGLQPPVLRVGNLDAVRDFTDVRDV
                     VRAYWLLLERGEAGQAYNVGSGQGRPIRWLLDTLLEMTPMAIHVELDPERLRPSDVPVS
                     ICDNRRLVAATGWQPRYDLRRTLQDLLDYWRREIALEGR"
     CDS             6444..7484
                     /NRPS_PKS="Domain: NAD_binding_4 (77-235). E-value:
                     1.8e-13. Score: 41.9. Matches aSDomain:
                     nrpspksdomains_ctg495_8_NAD_binding_4.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     nucleoside: TunD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     313.9; E-value: 2.1e-95)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg495_8"
                     /sec_met_domain="TunD (E-value: 4.5e-63, bitscore: 202.7,
                     seeds: 3, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 4.3e-14, bitscore:
                     41.9, seeds: 102, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 6.1e-17,
                     bitscore: 51.3, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 4.4e-17, bitscore:
                     51.7, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTMWRTLADKIRPGKKAMNILITGGAGFIGAHLANRLHRQGHHVR
                     VVDDLSSGDPSRLPSDIFFRRGDVRDVPNLWALLHDVDVVYHLAAKVSVPASILYPREY
                     NDVNVGGTVALLEACRDVGVGRVILASSATVYGDQQRQPVDEEARCRPGVPYAVSKLAA
                     EQYLFTMGRLSGFETVALRIFNAYGPGQPLPPSHAPIIPYAMRQIVQGGSVIVFGDGRQ
                     SRDFVYIDDVVDALVAAATASQVDQTIINVGSGRSTSINQLVELIGATVGRRPNLLHNR
                     EKSGGIHQLVADIRKAEQLLGYHPRVTLEQGLRRLLKEDPLFRDSGRPSSRDPLSTQPA
                     TDAPNQ"
     CDS_motif       6504..6566
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg495_8_0001"
                     /evalue="1.20E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg495_8"
                     /protein_end="41"
                     /protein_start="20"
                     /score="14.7"
                     /tool="antismash"
                     /translation="LITGGAGFIGAHLANRLHRQGH"
     aSDomain        6675..7148
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg495_8_NAD_binding_4.1"
                     /evalue="1.80E-13"
                     /label="ctg495_8_NAD_binding_4.1"
                     /locus_tag="ctg495_8"
                     /protein_end="235"
                     /protein_start="77"
                     /score="41.9"
                     /tool="antismash"
                     /translation="LLHDVDVVYHLAAKVSVPASILYPREYNDVNVGGTVALLEACRDV
                     GVGRVILASSATVYGDQQRQPVDEEARCRPGVPYAVSKLAAEQYLFTMGRLSGFETVAL
                     RIFNAYGPGQPLPPSHAPIIPYAMRQIVQGGSVIVFGDGRQSRDFVYIDDVVDAL"
     CDS             7468..8607
                     /locus_tag="ctg495_9"
                     /transl_table=11
                     /translation="MRPISEPAPQPRLPILALRAMALALLLGILAGALAGCSRSEMLAS
                     YLESHRDELQRPASMDQRPVRFVVEPGAPARAIAQELQAKGLIRDATLFEAYVRAQGVA
                     NRLEAGTFILSPSMSLVAIVEALQNAQAASITVTIPEGWRLEQTADFLSQADVLDGEEY
                     RRRAQLGDLTGLDVSEYGFLSARPAGASLEGYLFPDTYQLPAEGTTALDLLGRQLDNFG
                     VKVAPLHRQAVAEGATTLDLHAALTLASIVEREAVLPEERARIAGVYLNRLAAGMRLEA
                     DPTVQYAMGYQAESGQWWKTPVSLAEYSQVDSPYNTYLYPGLPPGPIASPGLESIRAVL
                     YPETHDFLYFVATPDGSGAHVFARTFQEHQENVARYLGR"
     CDS             complement(8972..9565)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M50"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg495_10"
                     /sec_met_domain="Peptidase_M50 (E-value: 3.9e-15, bitscore:
                     45.4, seeds: 56, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDWSASMAVSPIGFLTALLLVTIWHEAGHLLVARLVGIPVKLIAL
                     GLGPAVWKRSGDDGVNLVLRALPTGMSIGVPGRRDADGRLRRPIRHDILMAAGGPVASF
                     LLSLGLVGLAALIGPAAGIYPWLLATAALSTLMALLNLLPLPGLDGGHLLVLGIATLGF
                     QLSPQREVALHRYGLRLLALVVAVIAVVRMAGIF"
     CDS             10515..10691
                     /locus_tag="ctg495_11"
                     /transl_table=11
                     /translation="MFTLTHLLNWLSRNEEGQDLIEYALLIVLIVLVVAAVLPGVGSAI
                     STVFTDITTQLGG"
     CDS             10836..10976
                     /locus_tag="ctg495_12"
                     /transl_table=11
                     /translation="MKARIREERGSNLIEVALLIPLLFSLLIGVVDFGRAYHTYITMIN
                     AA"
ORIGIN
        1 aggcgaagtc cgggctccag cgaggccacc agatgccatc ctggaccacc cggtcgaact
       61 cgaagaggaa gtagacgtgg tggcgagcgt cgttggcccc ccagaaatag ccgggcagga
      121 ggaaaggagc caccgcgaag agggtcaacg ccagggccag ccagaagaga ccatcccgcc
      181 agaggggcgg gccgagccgg atggcctgga cgcgttcggg gacgggctta gcggccatag
      241 agcaccacct tgtcgtccgc gccgccgtcc acgggcaggc ggctgccgtc ccgccagtcg
      301 tagaggccga agtagtagcg gaggtctgcc tgggccgggt ctgcgggcag ctccagccga
      361 taggtggcgg tgatcacctg gcccacctgc caggtggtgg cggggcgatc tggcaggggc
      421 tggatgtcca gctgggccac cacctggagc tggccgctct ggggatccgg ctggagggcc
      481 tggaagaaga cgttgtagtc gaagccgatg gggcgcagag gctgccagac cacatccagc
      541 cgggcctggg gcggctggga ctcctcggtc agcttcgcct ccaggagcag gatgtcgttg
      601 tgcgggccca ggatggcggc aggacgcgcg ggaggccggt agttgacgaa gttcggggcc
      661 aggtaggtgt agctgctcag gaggaccagc aggagcaggc cgctccaata gccggcgcag
      721 cgcaggcggg gccgaagccg aggcaggctg ccagccatga gggccaggaa aggcgcggtg
      781 aagatcagca cctgccaggg gtaggtgaga aggcgttggc cccgggtcag gcgccagatg
      841 ggctcactga tcgccaggct gaggagaacg ctcagggcca ccacgagacc tccgaacccc
      901 aacagcctga cgagggctgg gtccccaccg gggggaagcg gcccggacca gtctgggtcc
      961 cgcccgttct gccagaggat ccaggccagg atcagggcga aggcgatggc ggggaagcca
     1021 agctggaagg ggtagccatc ctgccagccg ggctggctgg gcgccacctg ccagccgttg
     1081 cccaggagct ggaagacgtg gaggaagtgt tcctggaagg ggaccgaggc cggggcccgc
     1141 tgatcccaga ggggcaggag ggccaggaaa ccggccaggc ctgtgaccag gaccaccagc
     1201 ccgcccaggc ggtcccgctc cacccagagg acgtaggcca gaaggatgag ggtggccagg
     1261 agggccagac cggcctgggt gcgccacatc cagagggtgg cgatgacggc cacgccggcc
     1321 gcgccaggga agcgagtccc ggcgtagagg gtgaagccgg ccagggccac gggcagcagg
     1381 gccaggatca gggcgtcgcc caggctgccc cgaacgtaga ccgtggccag gaaaggggga
     1441 aagagggcgt agaggagacc ggccagagcc gcgccccggt cccccagccg ggggtagagc
     1501 cagacgtagg tccccaggct ggccaggatg aaggccaggg cgaaggtgag gcgcacggcg
     1561 gtcaccgggg ccaggcccag gaagaggatg agggggcggg cgatgaggaa agccgcgccg
     1621 ccgacccccc gccagaggtc tggctcggtg gcgatgtcgg ccagagggcc ggggttggca
     1681 gcgttgagga cggggacgaa gccctccagg gcctgccagt agccggggta ggtggtgggg
     1741 gcccaggcga agacgcccag gaggagcaag gtccacagcc ccaggcggct ggaaggccgg
     1801 gtgtcgatgg tgttcatggg ctgaattata gcgcgggagg gaggaaaggg ggaaaaggcg
     1861 gcaggcctag gaggttggtc gactggtcaa ttgggtggtt gtgggttagg acctgggagg
     1921 cgttccggag atccgcggag ggcagcgatg atccacggcc gctcgcctcc caccctagcg
     1981 gaatttcttg gactcggcgt tggcgtggaa gtccaggtag cggatccagc cccgggcggt
     2041 gagggggcca aactggttgt ggggcacgcg agtggtggct cctggatctc ggctggccag
     2101 ctcctggatc agggccaggg tctgcctccg ggtggcctgg aaagcctggc ccagctcgtc
     2161 ccagccggcg tcctggggcg gccggtagcc gtcgtactcg tccagggcga ggggttcccc
     2221 caggaagact cgcagccggg attgccccca gcgctcaatg ccgatgatgt ggctgaggat
     2281 ctggcggttg cgctctgtgt cccgggcccg gcggatgcgg tcctccagga tctgcccgga
     2341 gagggccagc ttgtcggcca gctgggcgaa gctcttgccc cggacggggc gctccaggat
     2401 gaaatctgcg gctattttct tgataggatc cagcacgccc atgggaaggt ccttgtctgt
     2461 gacatgtgat cttaccgatt cagcatcagg gtagcaacac cctcgcgctt cacccctgaa
     2521 cgttccccac ctccacccct tccaggggct cctgccggcc ctggtccagg aggacgccgc
     2581 ccccttccgc gccgccaggt tcgtccccgg cttctgcctg ggcttcctgg atctgcctgc
     2641 gccgcaaggc caacagctcc agctccggga ggctgaggcc gtagcggttg gccgggtgca
     2701 ggagcaggtc gatgaggtcc agctggacga tccgggccag ctcggcctgg ctgcggaagg
     2761 ggatccactg gaccggggcc cagctcagga aggcctgggc ggctggggtg cggggcccca
     2821 ccttgcgcag gggaaggacc gaacgctcca gacgccaggc cagctcccac tccgcgccgg
     2881 ccggcgcggt gatgtcctgg cccaagagga agtagaaacg gtcgcagcgg gccacccgct
     2941 cgaagagatc cgcgtaggcg atgccgctca gcgggctgcg ttggatctgg gcccggatct
     3001 ggacgggcag ctccgccagg gtgcggccga tgaccgcccg ctccggctcc aggtccgcgg
     3061 tggcgctgac gaagaggcgc agggtctcgg gcatggctgt tcctccgtcg acacaaccag
     3121 cactgccgct caactggctc tgccgctcaa ccggcatggc ggaccagcgg ccgaagcgct
     3181 tcgggtcgcc tatcccctgg gctgggccgc cagctcgtcc aggaaacgct ggaaggcctg
     3241 ggtcaccgcc tggggctgct ccagcatgac catgtggccg gcatcgggcg ccaggaccag
     3301 gcggctgtcc ggcaggtgct ggtggagata gtggctgtac ttgggcggcg tgagccggtc
     3361 ctccgctccg cagacgatga gtgcgggggt gtggatctgc tccagcttcc ccatgacgtc
     3421 gaaggcgtca caggcggcga agtcgttgtg gatcaccgag gccggcgtct ctcgcatgcg
     3481 ggccagcact gtggcgcgca tcttggggtc cacagagggg gccagggccc agtcggtgat
     3541 gagctccgtg gtggcctgga agtccctgag cagcccctcc aggatggccg gagccacccg
     3601 cagccgggct ccggtcccca ccaggcccat gccccggagc cgttccggat agttcagggc
     3661 gaagtccagg gcgatggccc cgcccatgga gtggccggcc aggacgaaag ggggcagatc
     3721 cagggcctgg gcgaaggccc ggaccacctc ccggtattcg gcgatggagg gccgagggcg
     3781 accgctggag cgaccgtggc cgggcatgtc cagggcgtag accgggccgc caggcaggcg
     3841 acgcagctgg ggcggccagt ggaggtggtt gccgccagag ccgtggacca ggagcagcgg
     3901 tgggtgcgga gggccttccc ctggggtgtg ggagaagccg tagaagatgg tttcgccgtg
     3961 caggtcaacg gtgggcatgg ctttcgctcc tcgctggaat cgagggggtg gacacgggga
     4021 gggtcccgtg cagggcgtcg gtgctttcgc tctggagatt caggactgct gggccttcag
     4081 ggccttctgc tcccggcgca gggcctccag gtccgcgtcc accatgatgc gcaccagctg
     4141 acggaagtcc acggccggct cccagcccag tttctccccg gccttggagg gatcccccac
     4201 cagcaggtcc acctccgcgg ggcggtagaa gcgcggatcc tggaccacga actcctgcca
     4261 gtccagcccc acgtagctga aggcctcctc cacgaactcc cggacgctgt gggtctcgcc
     4321 ggtggcgatg acgtagtcct cgggctcgtc ctgctgaagc atgagccaca tggcccggac
     4381 gtagtccggc gcgtagcccc agtcccggcg ggcgtccagg ttgcccaggc gcagttcctt
     4441 ggccaggccc agcttgatgc tggccaccgc gtgggtgatc ttgtgggtga cgaactccag
     4501 gccccggcgg gggctctcgt ggttgaagag gatccccgag caggcgaaga tgtcgtagct
     4561 ctcccggtag ttgacggtga tccagtggcc gtagaccttg gccacgccgt aggggctgcg
     4621 ggggtggaag ggggttttct cgctctgggg cacctctcgc accttaccga acatctcgct
     4681 gctggaggcc tggtagaagc ggatggaggg atccacgatg cggatggcgt ccaggatgcg
     4741 ggtgacgccc agggcggtga actccccagt gaggacgggc tgggtgaagc tggtgggcac
     4801 aaagctctgg gccgccaggt tgtagacctc ctgggggcgg tattcctgga ggatgctgat
     4861 caggctcatc tggtccagca gatccccctg gacgatctcg atccgcccct ggatgtgctt
     4921 gatgcggtcg aagttgatgg tgctggtccg gcgcaccatc cccaccacgt ggtagccctt
     4981 ctccaggagg aaatcggcca gatagctgcc gtcctgtcct gtgacaccgg tgatcaatgc
     5041 tgtgggcatg gtctactcct tcctcggttg aacttgggtt gggggaaagg gaggcggggc
     5101 ctggcaccag ctcaccccgc catcctgcga gccgctcccg gcctcctcat ctcgtcagcg
     5161 gccctccagg gcgatctctc ggcgccagta gtccaacaga tcctggaggg tgcggcgcag
     5221 atcgtagcgg ggctgccagc cggtggccgc caccagacgg cgattgtcgc agatgctcac
     5281 cggcacgtcg ctgggccgca ggcgctccgg gtccagctcc acgtggatgg ccatgggggt
     5341 catctccagc agggtgtcca gcagccagcg gatgggccgc ccctggccgc tgcccacgtt
     5401 gtaggcctgg cccgcctcac cgcgctccag gagcagccag taggcccgca ccacgtcccg
     5461 cacgtcggtg aaatcccgca ccgcgtccag gttccccacc cggagcaccg gcggctggag
     5521 accagcctcg atggccgcga tctgccgggc gaaggcgctg gccacgaaat cgtccgactg
     5581 gcgggggccg atgtggttga aactccgggc ccggaccgtg ggcaggcggt ggctgttcca
     5641 gtactggagc cccatcatgt cctgggcgat cttgctcacc ccgtaggggc tgttgggccg
     5701 aaagggcgtc tcctcgtcca cgggcagatc ctccggccga accaggccgt agacctcgtt
     5761 ggaggtcacc accagcaccg gctgctccgg tgcggttcgc tgcagggcct ccagcaggtt
     5821 gagctgggcc aggatgttca gctcgtaggc gttccacggc tggcgccagc tcccgcccac
     5881 atcgctccag gccgccaggt ggaaggtgcg gtccggctgc actgcctgga ccacctggct
     5941 cacccagagg ggattgcgca ggtcccctcg gtggaggtgg agctgttcca ggcgatggcg
     6001 gatgcgccac tggtgtcggt ggaggatgcc atggacctcc gcgtccgtct cgtccagcag
     6061 aaagtcggcc agatggctgc cggcgaaccc ggcgatcccc gtgaccagca cccgcacgtc
     6121 tcgctcctgt ctgtgatgcc tgggtcggtg acgccaccgc cacgaggccc cgggagagga
     6181 ccgactcccg gcgcttcgac ggagtccggt ggccgtgcaa aaaaggtcca acagtccgtt
     6241 cagtatagca gaaagccttt ttcatgggta aactgtcggc ctgagctttc tgaccgatcc
     6301 atttgctccg gctatcggcc agtgctatac tgcgcgggcg acacccaccg ccagggtcca
     6361 tctccttccg tgaccggatg acaatgcgac caggtggcaa tgcgaccgga taactgtgac
     6421 cggataaccg agaccggata accatgacca tgtggcgaac gcttgcggac aagatccgac
     6481 cgggaaagaa agccatgaac atactgatca ccggaggcgc gggcttcatc ggcgcccatc
     6541 tggccaatcg cctgcaccgc caggggcacc acgtgcgggt ggtggacgac ctgagcagcg
     6601 gggacccatc ccgcctgccc tcggacattt tcttccgccg gggggatgtg cgggacgtgc
     6661 ccaacctctg ggccctcctc cacgatgtgg atgtggtcta tcacctggcc gccaaggtga
     6721 gcgtccccgc ctctatcctt taccctcgcg agtacaacga cgtgaacgtg gggggcaccg
     6781 tggccctgct ggaggcctgc cgagatgtgg gggtgggccg ggtgatcctg gccagcagcg
     6841 ccacggtcta tggggaccag cagcggcagc ctgtggacga agaggcccga tgccggccgg
     6901 gcgtccccta cgcggtgagc aagctggccg cggagcagta cctcttcacc atgggccggc
     6961 tgagcggctt cgagacggtg gccttgcgca tcttcaacgc ctacgggccg ggccagccgc
     7021 tgccccccag ccatgcgccc atcatcccct acgccatgcg ccagatcgtc caggggggct
     7081 cggtcatcgt cttcggcgac ggtcgccagt cccgggattt cgtctacatc gatgatgtgg
     7141 tggacgccct ggtggccgcg gccacggcca gccaggtgga ccagaccatc atcaacgtgg
     7201 gctctggccg gagcacctcc atcaaccagc tggtcgagct catcggcgcc accgtgggcc
     7261 gccgccccaa tctgctccac aaccgggaga agagcggcgg catccaccag ctggtggcgg
     7321 acatccgcaa ggcggagcag ctgctgggct accaccctcg ggtgaccctg gagcaggggc
     7381 tgcgccgtct cctcaaggag gaccccctct tccgcgacag cggcagacct tcgtctcgag
     7441 atcccctgtc cacccagcca gccaccgatg cgcccaatca gtgaacccgc gccgcagccc
     7501 agactgccca tcctggccct gcgcgccatg gccctggccc tgctcctggg gatcctggcc
     7561 ggcgccctgg ccgggtgcag ccgaagcgag atgctggcca gctacctgga gagccaccga
     7621 gacgagctcc agcgcccagc cagcatggat caacggccgg tgcgcttcgt ggtggagcca
     7681 ggcgcccccg cccgagccat cgcccaggag ctccaggcca aagggctgat ccgagacgcc
     7741 actctcttcg aagcctacgt gcgggcgcaa ggggtggcca atcgcctgga ggccggcacc
     7801 ttcatcctta gccccagcat gtccctggtg gcgatcgtgg aggccctgca gaacgcccag
     7861 gccgccagca tcacggtgac catccccgag ggctggcggc tggagcagac ggccgatttc
     7921 ctgagccagg cggatgtgct ggacggggaa gagtaccgac gccgggccca gctgggggat
     7981 ctgaccggcc tggatgtgag cgagtacggc tttctctcgg ctcgaccggc cggggccagc
     8041 ctggagggct acctcttccc ggacacctac cagctccccg cggaggggac cacggccctg
     8101 gacctcctgg gccgccagct ggacaacttc ggggtcaagg tggcgccgct ccaccggcag
     8161 gcggtggcgg aaggcgccac gaccctggac ctccacgcgg ccctgaccct ggccagcatc
     8221 gtggagcggg aggcggtgct gccggaagag cgggcccgca ttgccggggt ctacctgaac
     8281 cgactggccg cgggcatgcg cctggaggcg gatcccacgg tccagtacgc catgggctac
     8341 caggccgaga gcggccagtg gtggaagacg ccggtctcct tggccgagta cagccaggtg
     8401 gatagcccct acaacaccta tctctacccc ggattgccgc ccgggcccat cgccagcccg
     8461 ggattggaga gcatccgagc cgtcctctac ccggagacgc acgacttcct ctacttcgtg
     8521 gccacgccgg acggcagcgg ggcccacgtc ttcgcccgca ccttccagga gcaccaggag
     8581 aacgtggccc gctatctggg ccgctgaagc tgggtagcga ggcttcggcc tggcccttcc
     8641 agggtcgctc cagacctggg agggcctcct gggaaagcga acgagacgca gattgacagc
     8701 cctatccggg ctggctacaa tgcggaagaa ggatccgggg agcgggtcgg tggcggaatg
     8761 gcagacgcgg cggacttaaa atccgctggg ggaaaccccg tgtgggttcg aatcccaccc
     8821 gacctaccac gcacagagat ccacagacaa gacagacgcg aagggaccgg cgctttcacg
     8881 ccggtccctt cgctcatggg gtatgggatg ggataagggg aggcataagt gcgggcagga
     8941 aaatcccttg aacagagccg cctgagcagt gctagaagat gccggccatg cgcaccaccg
     9001 cgatgacggc cacgaccagg gccagcaagc gcaggccgta acgatgcagc gccacctccc
     9061 gctggggcga gagctggaag cccagggtgg cgatccccag gaccaacaga tggccgccat
     9121 ccaggccggg caggggcagc aggttcagca gcgccatcaa ggtggaaagg gcagccgtgg
     9181 ccagaagcca ggggtagatc cctgcggcgg gtccgatgag agctgccagc cccaccaggc
     9241 ccagggagag gaggaagctg gccacaggcc ctcctgccgc catgaggata tcgtggcgga
     9301 tgggccgacg caggcgaccg tccgcgtccc ggcggccagg cacgccgatg gacatgcctg
     9361 tgggcagggc tcgcaacacc agatttacgc catcgtcccc ggagcgcttc cagacagcag
     9421 gccccagccc cagagcgatc agcttgaccg ggatgcccac caagcgggcc accagcaggt
     9481 gaccggcttc gtgccagatg gtcaccagca ggagagctgt cagaaatccg attggagaaa
     9541 ccgccatgct tgccgaccag tccatcgcac atctccctta gctacgctgt gaatcccttg
     9601 gcgacattgt aggcgacact gtaaacgatt cggtgtgatg aggggatggg gggacctcgt
     9661 ccgtccgagc ctgtctgaaa ttgccaaccc gtctatattg tcaacccgtc tatgcagatg
     9721 cgactacgtt tcctgcaaat ttctcctaca aatttcattg gctgcctgga gttggaggag
     9781 caacctgacc ggccaaatac gttttcgtca gccccggcct tacattatcg gccttcgttt
     9841 cctttcgata tagcctcttt gtgccattcg gtccagggaa ccagtttgta accttgttgt
     9901 aacttttgcg cccggtaaac ccgttgacag agctgctggc cgatgctaca ctggcaccga
     9961 agcaagcaga aagtactcct ctactcgagg caaacatcgt cgggacatca ttgtcacagg
    10021 ttgcctttcc tcacctggtt cactattccc agctgacaac ctgaagaaca aaaaccacat
    10081 atcgtgttcg acttgcttac ccccggcgag ttaaggaagc ttgcttgttg ctgtctcgta
    10141 ggccaggaac ccacaagtgg tcatgctcct tgcctgtgag agacggcgcc tgctggcgtc
    10201 gttcgatctg agaaatcgtt tcaagcagaa gccaagctgt accgcccaag ttgtactgtc
    10261 aaggaggcgc cctgcctgaa agatgtagcg tgacaatcgt tccagtggga tggcagcccc
    10321 catgtcccta ggatatccga acggtgtccg cgttcaaccc taagtactac gtctctatac
    10381 gtaatccatt attccgaaga cccgtgcttg tttgacctgt acaccctagc aaactgtcac
    10441 atcaacaccg tcacaccaac aacgcatcgc agaccatttt cgttcccagt ttcattccaa
    10501 ggaggagcaa catcatgttc acactcaccc acctgctcaa ctggctgtcc cgcaacgaag
    10561 agggccagga cctgatcgag tacgccctgc tcatcgtcct catcgtcctg gtcgtggccg
    10621 cggtcctgcc cggcgtgggc tccgccatca gcaccgtctt caccgacatc accacccagc
    10681 tgggcggcta agtcgccaag acgcttcaag ggcggtggcg gtgaccggtg acctgctggc
    10741 cgccactgcc ctcttctacg caccatgcct gtgcaccgca cacgaccgaa cgcatctgtg
    10801 aaacagagcg aaacgggttt cgaggagaga cggccatgaa agccagaatc cgtgaagaga
    10861 ggggctccaa cctcatcgag gtggccttgc tcattcccct cctgttttcg ctcctcatcg
    10921 gcgttgtgga cttcggcagg gcctaccaca cctacatcac catgatcaac gccgccc
//
